JPS56166116A - Carcinostatic agent - Google Patents
Carcinostatic agentInfo
- Publication number
- JPS56166116A JPS56166116A JP6884080A JP6884080A JPS56166116A JP S56166116 A JPS56166116 A JP S56166116A JP 6884080 A JP6884080 A JP 6884080A JP 6884080 A JP6884080 A JP 6884080A JP S56166116 A JPS56166116 A JP S56166116A
- Authority
- JP
- Japan
- Prior art keywords
- carcinostatic agent
- cancers
- phenothiazine
- active constituent
- phenothiazine derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000003327 cancerostatic effect Effects 0.000 title abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 4
- 239000000470 constituent Substances 0.000 abstract 2
- 150000002990 phenothiazines Chemical class 0.000 abstract 2
- WJFKNYWRSNBZNX-UHFFFAOYSA-N 10H-phenothiazine Chemical compound C1=CC=C2NC3=CC=CC=C3SC2=C1 WJFKNYWRSNBZNX-UHFFFAOYSA-N 0.000 abstract 1
- YQTCQNIPQMJNTI-UHFFFAOYSA-N 2,2-dimethylpropan-1-one Chemical group CC(C)(C)[C]=O YQTCQNIPQMJNTI-UHFFFAOYSA-N 0.000 abstract 1
- 241000232901 Nephroma Species 0.000 abstract 1
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
- 210000000941 bile Anatomy 0.000 abstract 1
- 210000000013 bile duct Anatomy 0.000 abstract 1
- 210000000481 breast Anatomy 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 210000003238 esophagus Anatomy 0.000 abstract 1
- 210000000232 gallbladder Anatomy 0.000 abstract 1
- 210000000214 mouth Anatomy 0.000 abstract 1
- 208000025351 nephroma Diseases 0.000 abstract 1
- 210000000496 pancreas Anatomy 0.000 abstract 1
- 229950000688 phenothiazine Drugs 0.000 abstract 1
- 210000000664 rectum Anatomy 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 210000002784 stomach Anatomy 0.000 abstract 1
- 210000004291 uterus Anatomy 0.000 abstract 1
Landscapes
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE: A safe carcinostatic agent, containing a phenothiazine derivative as an active constituent, and capable of acting of tumors specifically without side effects.
CONSTITUTION: A carcinostatic agent containing a phenothiazine derivative of the formula (Y is H, lower alkanoyl other than pivaloyl or benzoyl), e.g. phenothiazine, 10-acethyphenothiazine or 10-propionylphenothizaine, as an active constituent. The pharmaceutical is characterized by a powerful action on solid cancers and effective against various cancers, e.g. cancers of the stomach, rectum, breast, uterus, oral cavity, esophagus, gallbladder, bile duct, bile passages and pancreas and nephroma.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6884080A JPS56166116A (en) | 1980-05-26 | 1980-05-26 | Carcinostatic agent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6884080A JPS56166116A (en) | 1980-05-26 | 1980-05-26 | Carcinostatic agent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS56166116A true JPS56166116A (en) | 1981-12-21 |
Family
ID=13385286
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP6884080A Pending JPS56166116A (en) | 1980-05-26 | 1980-05-26 | Carcinostatic agent |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS56166116A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5371081A (en) * | 1991-08-12 | 1994-12-06 | St. Jude Children's Research Hospital | N-substituted phenoxazines for treating multidrug resistant cancer cells |
| JP2014534953A (en) * | 2011-09-26 | 2014-12-25 | ポハン ユニバーシティー オブ サイエンス アンド テクノロジー インダストリー アカデミー コーペレーション コープス | Α-type zinc phthalocyanine nanowire having improved water solubility and water dispersibility, α-type zinc phthalocyanine nanowire / phenothiazine composite, and method for producing the same |
| WO2019093379A1 (en) * | 2017-11-07 | 2019-05-16 | 学校法人自治医科大学 | Agent for improving mitochondrial dysfunction, preventative or therapeutic agent for diseases or symptoms caused by mitochondrial dysfunction, and applications therefor |
-
1980
- 1980-05-26 JP JP6884080A patent/JPS56166116A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5371081A (en) * | 1991-08-12 | 1994-12-06 | St. Jude Children's Research Hospital | N-substituted phenoxazines for treating multidrug resistant cancer cells |
| JP2014534953A (en) * | 2011-09-26 | 2014-12-25 | ポハン ユニバーシティー オブ サイエンス アンド テクノロジー インダストリー アカデミー コーペレーション コープス | Α-type zinc phthalocyanine nanowire having improved water solubility and water dispersibility, α-type zinc phthalocyanine nanowire / phenothiazine composite, and method for producing the same |
| WO2019093379A1 (en) * | 2017-11-07 | 2019-05-16 | 学校法人自治医科大学 | Agent for improving mitochondrial dysfunction, preventative or therapeutic agent for diseases or symptoms caused by mitochondrial dysfunction, and applications therefor |
| US11369615B2 (en) | 2017-11-07 | 2022-06-28 | Jichi Medical University | Agent for improving mitochondrial dysfunction, preventative or therapeutic agent for diseases or symptoms caused by mitochondrial dysfunction, and applications therefor |
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