JPS5527140A - Novel 2-substituted imidazolecarboxamide derivative - Google Patents
Novel 2-substituted imidazolecarboxamide derivativeInfo
- Publication number
- JPS5527140A JPS5527140A JP9942178A JP9942178A JPS5527140A JP S5527140 A JPS5527140 A JP S5527140A JP 9942178 A JP9942178 A JP 9942178A JP 9942178 A JP9942178 A JP 9942178A JP S5527140 A JPS5527140 A JP S5527140A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- derivative
- remedy
- substituted
- novel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:An imidazole derivative of formula I: (X is O, S, or imino group), and its salts.
EXAMPLE: 2-(2-Furyl)-5-hydroxy-1H-imidazole-4-carboxamide.
USE: Carcinostatic and immunization enhancing actions. Useful as an immunotherapeutic agent for tumors, as a remedy for incurable diseases, e.g. collagenosis, and as a remedy for infection due to the viral, bacterial, and helminph pathogens.
PROCESS: An imidoester derivative of formula II: (A is formimidoyl having a substituent on the carbon atom) or its salt or an orthoester of formula III: (B is lower alkyl group) is reacted with aminomalonamide in the presence of an organic solvent, e.g. methanol, at 0W100°C to give the compound of formula I.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9942178A JPS5527140A (en) | 1978-08-14 | 1978-08-14 | Novel 2-substituted imidazolecarboxamide derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9942178A JPS5527140A (en) | 1978-08-14 | 1978-08-14 | Novel 2-substituted imidazolecarboxamide derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5527140A true JPS5527140A (en) | 1980-02-27 |
JPS6257633B2 JPS6257633B2 (en) | 1987-12-02 |
Family
ID=14246996
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP9942178A Granted JPS5527140A (en) | 1978-08-14 | 1978-08-14 | Novel 2-substituted imidazolecarboxamide derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5527140A (en) |
-
1978
- 1978-08-14 JP JP9942178A patent/JPS5527140A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS6257633B2 (en) | 1987-12-02 |
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