JPS55138394A - Production of androstane compound through fermentation process - Google Patents
Production of androstane compound through fermentation processInfo
- Publication number
- JPS55138394A JPS55138394A JP4494979A JP4494979A JPS55138394A JP S55138394 A JPS55138394 A JP S55138394A JP 4494979 A JP4494979 A JP 4494979A JP 4494979 A JP4494979 A JP 4494979A JP S55138394 A JPS55138394 A JP S55138394A
- Authority
- JP
- Japan
- Prior art keywords
- androstane
- sterol
- production
- mycobacterium
- fermentation process
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- -1 androstane compound Chemical class 0.000 title abstract 2
- 238000000855 fermentation Methods 0.000 title 1
- 230000004151 fermentation Effects 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 229930182558 Sterol Natural products 0.000 abstract 3
- 235000003702 sterols Nutrition 0.000 abstract 3
- QZLYKIGBANMMBK-UGCZWRCOSA-N 5α-Androstane Chemical compound C([C@@H]1CC2)CCC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CCC[C@@]2(C)CC1 QZLYKIGBANMMBK-UGCZWRCOSA-N 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 241000187912 Mycobacterium diernhoferi Species 0.000 abstract 2
- 150000003432 sterols Chemical class 0.000 abstract 2
- 239000000758 substrate Substances 0.000 abstract 2
- 241000186359 Mycobacterium Species 0.000 abstract 1
- 150000001441 androstanes Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 150000002170 ethers Chemical class 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
PURPOSE: A mutant from Mycobacterium microorganism is cultured in a medium containing sterol as the substrate to collect androstane compounds formed.
CONSTITUTION: A mutant that belongs to Mycobacterium diernhoferi and has lost the enzyme decomposing androstane or contains it in activity-reduced, form, which is included enzyme in the wild mold in high active form, e.g., Mycobacterium diernhoferi MCI-1298 and 1299 (FERM-4927 and 4928), is cultured in a substrate containing a sterol compound selected from sterol, its C-3 ester, and ether derivatives and their oxidative intermediates to produce androstane.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4494979A JPS55138394A (en) | 1979-04-13 | 1979-04-13 | Production of androstane compound through fermentation process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4494979A JPS55138394A (en) | 1979-04-13 | 1979-04-13 | Production of androstane compound through fermentation process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS55138394A true JPS55138394A (en) | 1980-10-29 |
Family
ID=12705730
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP4494979A Pending JPS55138394A (en) | 1979-04-13 | 1979-04-13 | Production of androstane compound through fermentation process |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS55138394A (en) |
-
1979
- 1979-04-13 JP JP4494979A patent/JPS55138394A/en active Pending
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