JPS55138389A - Preparation of amino alcohols - Google Patents
Preparation of amino alcoholsInfo
- Publication number
- JPS55138389A JPS55138389A JP4589979A JP4589979A JPS55138389A JP S55138389 A JPS55138389 A JP S55138389A JP 4589979 A JP4589979 A JP 4589979A JP 4589979 A JP4589979 A JP 4589979A JP S55138389 A JPS55138389 A JP S55138389A
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- hydrolyzing
- formula
- preparation
- amino alcohols
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001414 amino alcohols Chemical class 0.000 title abstract 2
- -1 2-substituted aziridines Chemical class 0.000 abstract 3
- 230000003301 hydrolyzing effect Effects 0.000 abstract 2
- 244000005700 microbiome Species 0.000 abstract 2
- 241000193830 Bacillus <bacterium> Species 0.000 abstract 1
- 244000063299 Bacillus subtilis Species 0.000 abstract 1
- 235000014469 Bacillus subtilis Nutrition 0.000 abstract 1
- 241000588698 Erwinia Species 0.000 abstract 1
- 241000588748 Klebsiella Species 0.000 abstract 1
- 241000588769 Proteus <enterobacteria> Species 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 1
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
PURPOSE: To prepare high purity amino alchols, by hydrolyzing 2-substituted aziridines with a material containing microorganisms.
CONSTITUTION: 2-Substituted aziridines of formula I [R is (un)substituted alkyl or aralkyl] are made to contact with microorganisms belonging to Bacillus, Proteus, Erwinia or Klebsiella genus and capable of opening and hydrolyzing the 2-substituted aziridine ring selectively, e.g. Bacillus subtilis No. 13 (FERM-P No.4760), culturing liquid, cells, or treated cells thereof, to obtain amino alcohol of formula II.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4589979A JPS55138389A (en) | 1979-04-14 | 1979-04-14 | Preparation of amino alcohols |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4589979A JPS55138389A (en) | 1979-04-14 | 1979-04-14 | Preparation of amino alcohols |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS55138389A true JPS55138389A (en) | 1980-10-29 |
| JPS5722556B2 JPS5722556B2 (en) | 1982-05-13 |
Family
ID=12732082
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP4589979A Granted JPS55138389A (en) | 1979-04-14 | 1979-04-14 | Preparation of amino alcohols |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS55138389A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4950606A (en) * | 1989-06-22 | 1990-08-21 | Celgene Corporation | Enantiomeric enrichment and stereoselective synthesis of chiral amines |
| JPH02256654A (en) * | 1988-10-07 | 1990-10-17 | Merrell Dow Pharmaceut Inc | Novel peptidase inhibitors |
| US5169780A (en) * | 1989-06-22 | 1992-12-08 | Celgene Corporation | Enantiomeric enrichment and stereoselective synthesis of chiral amines |
| US5300437A (en) * | 1989-06-22 | 1994-04-05 | Celgene Corporation | Enantiomeric enrichment and stereoselective synthesis of chiral amines |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4850739A (en) * | 1971-10-26 | 1973-07-17 | ||
| JPS5016555A (en) * | 1973-06-08 | 1975-02-21 | ||
| JPS53111750A (en) * | 1972-10-12 | 1978-09-29 | Rca Corp | Method of manufacturing information recording body |
-
1979
- 1979-04-14 JP JP4589979A patent/JPS55138389A/en active Granted
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4850739A (en) * | 1971-10-26 | 1973-07-17 | ||
| JPS53111750A (en) * | 1972-10-12 | 1978-09-29 | Rca Corp | Method of manufacturing information recording body |
| JPS5016555A (en) * | 1973-06-08 | 1975-02-21 |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02256654A (en) * | 1988-10-07 | 1990-10-17 | Merrell Dow Pharmaceut Inc | Novel peptidase inhibitors |
| US4950606A (en) * | 1989-06-22 | 1990-08-21 | Celgene Corporation | Enantiomeric enrichment and stereoselective synthesis of chiral amines |
| US5169780A (en) * | 1989-06-22 | 1992-12-08 | Celgene Corporation | Enantiomeric enrichment and stereoselective synthesis of chiral amines |
| US5300437A (en) * | 1989-06-22 | 1994-04-05 | Celgene Corporation | Enantiomeric enrichment and stereoselective synthesis of chiral amines |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5722556B2 (en) | 1982-05-13 |
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