JPS55131392A - Enzyme fixing membrane and its preparation - Google Patents
Enzyme fixing membrane and its preparationInfo
- Publication number
- JPS55131392A JPS55131392A JP3744079A JP3744079A JPS55131392A JP S55131392 A JPS55131392 A JP S55131392A JP 3744079 A JP3744079 A JP 3744079A JP 3744079 A JP3744079 A JP 3744079A JP S55131392 A JPS55131392 A JP S55131392A
- Authority
- JP
- Japan
- Prior art keywords
- membrane
- enzyme
- fixing
- microholes
- surface active
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000012528 membrane Substances 0.000 title abstract 6
- 108090000790 Enzymes Proteins 0.000 title abstract 5
- 102000004190 Enzymes Human genes 0.000 title abstract 5
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- 239000007864 aqueous solution Substances 0.000 abstract 2
- 239000004094 surface-active agent Substances 0.000 abstract 2
- 239000004809 Teflon Substances 0.000 abstract 1
- 229920006362 Teflon® Polymers 0.000 abstract 1
- 108010046334 Urease Proteins 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000001879 gelation Methods 0.000 abstract 1
- 230000007774 longterm Effects 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 239000011347 resin Substances 0.000 abstract 1
- 229920005989 resin Polymers 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Landscapes
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Abstract
PURPOSE: An enzyme fixing membrane capable of being made into extremely then, having a sufficient mechanical strength, obtained by filling communicating microholes of porous Teflon membrane with an oxygen-containing gel substance.
CONSTITUTION: A porous Teflon-membrane is treated with an organic solvent having offinity (e.g., methanol) and processed with a surface active agent-containing aqueous solution. Excess surface active agent is removed if necessary, and the membrane is immersed in an aqueous solution having an enzyme (e.g., urease) and a fixing agent (e.g., a photosensitive resin) so that the communicating microholes are impregnated with the solution, which is submitted to gelation. The resulting enzyme fixing membrane is applied to the indicated electrode to construct an enzyme electrode, which has sufficient functions as a sensor with respect to response speed and long-term stability and exhibits stable output power in blood serum and whole blood while being hardly polluted.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3744079A JPS55131392A (en) | 1979-03-29 | 1979-03-29 | Enzyme fixing membrane and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3744079A JPS55131392A (en) | 1979-03-29 | 1979-03-29 | Enzyme fixing membrane and its preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS55131392A true JPS55131392A (en) | 1980-10-13 |
JPS5741238B2 JPS5741238B2 (en) | 1982-09-02 |
Family
ID=12497562
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP3744079A Granted JPS55131392A (en) | 1979-03-29 | 1979-03-29 | Enzyme fixing membrane and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55131392A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5896246A (en) * | 1981-11-05 | 1983-06-08 | マイルス・ラボラトリ−ズ・インコ−ポレ−テツド | Method for producing enzyme membranes in which enzymes are protected and wrapped in capsules |
US4539294A (en) * | 1982-09-30 | 1985-09-03 | Akzona Incorporated | Immobilization of proteins on polymeric supports |
-
1979
- 1979-03-29 JP JP3744079A patent/JPS55131392A/en active Granted
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5896246A (en) * | 1981-11-05 | 1983-06-08 | マイルス・ラボラトリ−ズ・インコ−ポレ−テツド | Method for producing enzyme membranes in which enzymes are protected and wrapped in capsules |
US4539294A (en) * | 1982-09-30 | 1985-09-03 | Akzona Incorporated | Immobilization of proteins on polymeric supports |
Also Published As
Publication number | Publication date |
---|---|
JPS5741238B2 (en) | 1982-09-02 |
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