JPS55124797A - Phosphorylation of nucleotide - Google Patents
Phosphorylation of nucleotideInfo
- Publication number
- JPS55124797A JPS55124797A JP3355879A JP3355879A JPS55124797A JP S55124797 A JPS55124797 A JP S55124797A JP 3355879 A JP3355879 A JP 3355879A JP 3355879 A JP3355879 A JP 3355879A JP S55124797 A JPS55124797 A JP S55124797A
- Authority
- JP
- Japan
- Prior art keywords
- nucleotide
- captured
- agent
- salt
- long
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002773 nucleotide Substances 0.000 title abstract 5
- 125000003729 nucleotide group Chemical group 0.000 title abstract 5
- 230000026731 phosphorylation Effects 0.000 title 1
- 238000006366 phosphorylation reaction Methods 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- XHXFXVLFKHQFAL-UHFFFAOYSA-N phosphoryl trichloride Chemical compound ClP(Cl)(Cl)=O XHXFXVLFKHQFAL-UHFFFAOYSA-N 0.000 abstract 2
- 229920000642 polymer Polymers 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 229910019213 POCl3 Inorganic materials 0.000 abstract 1
- 150000003863 ammonium salts Chemical class 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000012024 dehydrating agents Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 230000000865 phosphorylative effect Effects 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
- IMNIMPAHZVJRPE-UHFFFAOYSA-N triethylenediamine Chemical compound C1CN2CCN1CC2 IMNIMPAHZVJRPE-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Saccharide Compounds (AREA)
Abstract
PURPOSE: To oxidize a nucleotide in one stage without requiring a dehydrating agent, by using the nucleotide captured in a specific organic ammonium salt as a raw material.
CONSTITUTION: A nucleotide is brought into contact with and captured in an insoluble aromatic high polymer bonded to an N,N'-di long-chain alkyl or alkenyl diammonium salt or N-long-chain alkyl or alkenylammonium salt of 1,4-diazobicyclo[2.2.2]-octane. A compound of formula I or II (R1 and R2 are 8W22C alkyl or alkenyl groups; P is insoluble aromatic high polymer; X1 - and X2 - are anions) may be used as the agent. The captured nucleotide in then phosphorylated with a phosphorylating agent, e.g. POCl3, in an organic solvent.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3355879A JPS55124797A (en) | 1979-03-22 | 1979-03-22 | Phosphorylation of nucleotide |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3355879A JPS55124797A (en) | 1979-03-22 | 1979-03-22 | Phosphorylation of nucleotide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS55124797A true JPS55124797A (en) | 1980-09-26 |
Family
ID=12389873
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP3355879A Pending JPS55124797A (en) | 1979-03-22 | 1979-03-22 | Phosphorylation of nucleotide |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS55124797A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59152398A (en) * | 1983-02-18 | 1984-08-31 | Res Dev Corp Of Japan | Synthesis of nucleotide derivative |
-
1979
- 1979-03-22 JP JP3355879A patent/JPS55124797A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59152398A (en) * | 1983-02-18 | 1984-08-31 | Res Dev Corp Of Japan | Synthesis of nucleotide derivative |
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