JPS54154714A - Nitrosourea derivative and its preparation - Google Patents
Nitrosourea derivative and its preparationInfo
- Publication number
- JPS54154714A JPS54154714A JP6345978A JP6345978A JPS54154714A JP S54154714 A JPS54154714 A JP S54154714A JP 6345978 A JP6345978 A JP 6345978A JP 6345978 A JP6345978 A JP 6345978A JP S54154714 A JPS54154714 A JP S54154714A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- preparation
- aldohexopyranose
- nitrosation
- nitrosourea derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- OSTGTTZJOCZWJG-UHFFFAOYSA-N nitrosourea Chemical class NC(=O)N=NO OSTGTTZJOCZWJG-UHFFFAOYSA-N 0.000 title abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 230000009935 nitrosation Effects 0.000 abstract 2
- 238000007034 nitrosation reaction Methods 0.000 abstract 2
- IOVCWXUNBOPUCH-UHFFFAOYSA-N Nitrous acid Chemical compound ON=O IOVCWXUNBOPUCH-UHFFFAOYSA-N 0.000 abstract 1
- 125000003804 aldohexopyranosyl group Chemical class [H]OC([H])([H])C1([H])OC([H])(*)C([H])(O[H])C([H])(O[H])C1([H])O[H] 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 230000002622 anti-tumorigenesis Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
- 150000003672 ureas Chemical class 0.000 abstract 1
Landscapes
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (30)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6345978A JPS5919555B2 (ja) | 1978-05-26 | 1978-05-26 | ニトロソ尿素透導体及びその製法 |
US05/922,811 US4182757A (en) | 1977-07-29 | 1978-07-10 | Novel nitrosourea compounds and process for preparing the same |
FI782215A FI65439C (fi) | 1977-07-29 | 1978-07-11 | Foerfarande foer framstaellning av nitrosoureaderivat med anti-turmoeraktivitet |
MX10099078U MX5407E (es) | 1977-07-29 | 1978-07-20 | Procedimiento para preparar compuestos de nitrosourea |
DE2832127A DE2832127C2 (de) | 1977-07-29 | 1978-07-21 | 1-(2-Chloräthyl)-1-nitroso-3-substituierte-3-glycosylharnstoffe, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen |
DE2858078A DE2858078C2 (de) | 1977-07-29 | 1978-07-21 | 2-Chlorethylnitrosoharnstoffe, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen |
DE19782857911 DE2857911C2 (de) | 1977-07-29 | 1978-07-21 | 1-(2-Chloräthyl)-3-substituierte-3-glycosylharnstoffe, Verfahren zu deren Herstellung sowie deren Verwendung zur Herstellung von 1-(2-Chloräthyl)-1-nitroso-3-substituierten-3-glycosylharnstoffen |
CA307,987A CA1097624A (en) | 1977-07-29 | 1978-07-24 | Nitrosourea compounds and process for preparing the same |
PH21418A PH13936A (en) | 1977-07-29 | 1978-07-25 | Novel nitrosourea compounds and process for preparing the same |
DK331978A DK331978A (da) | 1977-07-29 | 1978-07-26 | Nitrosourinstofderivater og fremgangsmaade til femstilling deraf |
SE7808162A SE435501B (sv) | 1977-07-29 | 1978-07-26 | Nitrosokarbamidderivat samt farmakologisk komposition innehallande detta |
AT546178A AT360553B (de) | 1977-07-29 | 1978-07-27 | Verfahren zur herstellung neuer nitroso- harnstoffverbindungen |
HU78TA1491A HU176891B (en) | 1977-07-29 | 1978-07-27 | Process for preparing nitroso-carbamide derivatives |
CH809678A CH636626A5 (de) | 1977-07-29 | 1978-07-27 | Nitroso-harnstoffverbindungen und verfahren zu ihrer herstellung und verwendung derselben in therapeutischen mitteln. |
IT68797/78A IT1160450B (it) | 1977-07-29 | 1978-07-27 | Composti nitrosureici e procedimento per la loro preparazione |
PT68359A PT68359A (en) | 1977-07-29 | 1978-07-28 | Process for preparing novel nitrosourea derivatives |
BE189567A BE869352A (fr) | 1977-07-29 | 1978-07-28 | Nouvelles nitrosourees et leur application |
FR7822477A FR2403994A1 (fr) | 1977-07-29 | 1978-07-28 | Nouvelles 1-(2-chloroethyl)-1-nitrosourees utiles notamment comme agents antitumoraux et leur procede de preparation |
NL7808036A NL7808036A (nl) | 1977-07-29 | 1978-07-28 | Nitrosoureum derivaten. |
PL1978208701A PL111784B1 (en) | 1977-07-29 | 1978-07-28 | Method of manufacture of novel derivatives of nitrosourea |
AR273129A AR219331A1 (es) | 1977-07-29 | 1978-07-28 | Nuevo derivado de la urea,particularmente util como intermediario no farmacologico en la produccion de un compuesto nitrosourea y procedimiento para la preparacion del compuesto nitrosourea |
SU782643999A SU908247A3 (ru) | 1977-07-29 | 1978-07-28 | Способ получени производных нитрозомочевины |
EG46478A EG13375A (en) | 1977-07-29 | 1978-07-29 | Nitrosourea compounds and process for preparing the same |
AU38491/78A AU525239B2 (en) | 1977-07-29 | 1978-07-31 | Improvements in or relating to nitrosourea compounds |
GB8027528A GB2053918B (en) | 1977-07-29 | 1978-07-31 | Urea compounds |
CS785045A CS216918B2 (en) | 1977-07-29 | 1978-07-31 | Method of preparation of the nitrurea |
GB7831712A GB2002370B (en) | 1977-07-29 | 1978-07-31 | Nitrosourea compounds and process for preparing the same |
FR8105772A FR2475040B1 (ja) | 1977-07-29 | 1981-03-23 | |
FR8115054A FR2485541B1 (ja) | 1977-07-29 | 1981-08-03 | |
FR8205133A FR2499577A1 (fr) | 1977-07-29 | 1982-03-25 | Nouvelles 1-(2-chloroethyl)-1-nitrosourees-3-substituees par un reste de sucre, utiles notamment comme agents antitumoraux et leur procede de preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6345978A JPS5919555B2 (ja) | 1978-05-26 | 1978-05-26 | ニトロソ尿素透導体及びその製法 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS54154714A true JPS54154714A (en) | 1979-12-06 |
JPS5919555B2 JPS5919555B2 (ja) | 1984-05-07 |
Family
ID=13229834
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP6345978A Expired JPS5919555B2 (ja) | 1977-07-29 | 1978-05-26 | ニトロソ尿素透導体及びその製法 |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5919555B2 (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009139181A1 (ja) | 2008-05-15 | 2009-11-19 | 大正製薬株式会社 | 4員環構造を有する10a-アザライド化合物 |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0120301Y2 (ja) * | 1984-11-15 | 1989-06-15 |
-
1978
- 1978-05-26 JP JP6345978A patent/JPS5919555B2/ja not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009139181A1 (ja) | 2008-05-15 | 2009-11-19 | 大正製薬株式会社 | 4員環構造を有する10a-アザライド化合物 |
Also Published As
Publication number | Publication date |
---|---|
JPS5919555B2 (ja) | 1984-05-07 |
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