JPS5414593A - Preparation of cytidine diphosphate choline ester - Google Patents
Preparation of cytidine diphosphate choline esterInfo
- Publication number
- JPS5414593A JPS5414593A JP7775877A JP7775877A JPS5414593A JP S5414593 A JPS5414593 A JP S5414593A JP 7775877 A JP7775877 A JP 7775877A JP 7775877 A JP7775877 A JP 7775877A JP S5414593 A JPS5414593 A JP S5414593A
- Authority
- JP
- Japan
- Prior art keywords
- choline ester
- preparation
- cytidine diphosphate
- diphosphate choline
- ochbline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- RZZPDXZPRHQOCG-OJAKKHQRSA-O CDP-choline(1+) Chemical compound O[C@@H]1[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OCC[N+](C)(C)C)O[C@H]1N1C(=O)N=C(N)C=C1 RZZPDXZPRHQOCG-OJAKKHQRSA-O 0.000 title abstract 2
- OPTASPLRGRRNAP-UHFFFAOYSA-N cytosine Chemical compound NC=1C=CNC(=O)N=1 OPTASPLRGRRNAP-UHFFFAOYSA-N 0.000 abstract 2
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 abstract 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 210000004556 brain Anatomy 0.000 abstract 1
- 229940104302 cytosine Drugs 0.000 abstract 1
- 229940067606 lecithin Drugs 0.000 abstract 1
- 235000010445 lecithin Nutrition 0.000 abstract 1
- 239000000787 lecithin Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 150000003016 phosphoric acids Chemical class 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
PURPOSE: To prepare cytidine diphosphate choline ester useful as a precursor for the synthesis of lecithin and a remedy for brain troubles, economically, by treating yeast with a liquid containing cytosine, a sugar, ochbline, a phosphoric acid salt, and a surface active agent.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7775877A JPS599158B2 (en) | 1977-07-01 | 1977-07-01 | Production method of choline cytidine diphosphate |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7775877A JPS599158B2 (en) | 1977-07-01 | 1977-07-01 | Production method of choline cytidine diphosphate |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5414593A true JPS5414593A (en) | 1979-02-02 |
JPS599158B2 JPS599158B2 (en) | 1984-02-29 |
Family
ID=13642817
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP7775877A Expired JPS599158B2 (en) | 1977-07-01 | 1977-07-01 | Production method of choline cytidine diphosphate |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS599158B2 (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58189001A (en) * | 1982-04-15 | 1983-11-04 | シエル・インタ−ナシヨナル・リサ−チ・マ−トスハツペイ・ベ−・ヴエ− | Liquid-gas contact device |
EP0553821A1 (en) | 1992-01-30 | 1993-08-04 | Kyowa Hakko Kogyo Co., Ltd. | Process for producing cytidine diphosphate choline |
JP2013132270A (en) * | 2011-12-27 | 2013-07-08 | Meiji Co Ltd | Yeast and mold detector |
CN111647636A (en) * | 2020-06-28 | 2020-09-11 | 南京同凯兆业生物技术有限责任公司 | Method for catalytically synthesizing citicoline by using yeast whole cells |
-
1977
- 1977-07-01 JP JP7775877A patent/JPS599158B2/en not_active Expired
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58189001A (en) * | 1982-04-15 | 1983-11-04 | シエル・インタ−ナシヨナル・リサ−チ・マ−トスハツペイ・ベ−・ヴエ− | Liquid-gas contact device |
EP0553821A1 (en) | 1992-01-30 | 1993-08-04 | Kyowa Hakko Kogyo Co., Ltd. | Process for producing cytidine diphosphate choline |
CN1060215C (en) * | 1992-01-30 | 2001-01-03 | 协和发酵工业株式会社 | Process for producing cytidine diphosphate choline |
JP2013132270A (en) * | 2011-12-27 | 2013-07-08 | Meiji Co Ltd | Yeast and mold detector |
CN111647636A (en) * | 2020-06-28 | 2020-09-11 | 南京同凯兆业生物技术有限责任公司 | Method for catalytically synthesizing citicoline by using yeast whole cells |
CN111647636B (en) * | 2020-06-28 | 2022-04-29 | 南京同凯兆业生物技术有限责任公司 | Method for catalytically synthesizing citicoline by using yeast whole cells |
Also Published As
Publication number | Publication date |
---|---|
JPS599158B2 (en) | 1984-02-29 |
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