JPS53104719A - Chimosine fraction 5 - Google Patents

Chimosine fraction 5

Info

Publication number: JPS53104719A
Authority: JP; Japan
Prior art keywords: fraction; thymosin fraction; reconstitution; permeate; phenolic type
Prior art date: 1977-02-22
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

JP1774678A

Other languages

English (en)

Other versions

JPS618806B2 (ja

Inventor

Kootonii Maguregaa Uerudon

Reon Niyuumaaku Harorudo

Haaman Rameru Aamin

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

F Hoffmann La Roche AG

Original Assignee

F Hoffmann La Roche AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-02-22

Filing date

1978-02-20

Publication date

1978-09-12

1978-02-20 Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG

1978-09-12 Publication of JPS53104719A publication Critical patent/JPS53104719A/ja

1986-03-18 Publication of JPS618806B2 publication Critical patent/JPS618806B2/ja

Status Granted legal-status Critical Current

Links

239000004599 antimicrobial Substances 0.000 abstract 2
239000006172 buffering agent Substances 0.000 abstract 2
239000012466 permeate Substances 0.000 abstract 2
ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 2
108700016958 thymosin fraction 5 Proteins 0.000 abstract 2
108010046075 Thymosin Proteins 0.000 abstract 1
102000007501 Thymosin Human genes 0.000 abstract 1
239000007864 aqueous solution Substances 0.000 abstract 1
239000000872 buffer Substances 0.000 abstract 1
239000002158 endotoxin Substances 0.000 abstract 1
239000012528 membrane Substances 0.000 abstract 1
239000002510 pyrogen Substances 0.000 abstract 1
239000007787 solid Substances 0.000 abstract 1
LCJVIYPJPCBWKS-NXPQJCNCSA-N thymosin Chemical compound SC[C@@H](N)C(=O)N[C@H](CO)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CO)C(=O)N[C@H](CO)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@H]([C@H](C)O)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](C(C)C)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@H](CCC(O)=O)C(O)=O LCJVIYPJPCBWKS-NXPQJCNCSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2292—Thymosin; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Emergency Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Endocrinology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Medicinal Preparation (AREA)

JP1774678A 1977-02-22 1978-02-20 Chimosine fraction 5 Granted JPS53104719A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US05/770,480 US4082737A (en)	1977-02-22	1977-02-22	Stabilized thymosin composition and method

Publications (2)

Publication Number	Publication Date
JPS53104719A true JPS53104719A (en)	1978-09-12
JPS618806B2 JPS618806B2 (ja)	1986-03-18

Family

ID=25088687

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP1774678A Granted JPS53104719A (en)	1977-02-22	1978-02-20	Chimosine fraction 5

Country Status (20)

Country	Link
US (1)	US4082737A (ja)
JP (1)	JPS53104719A (ja)
AT (1)	AT363177B (ja)
AU (1)	AU516946B2 (ja)
BE (1)	BE864139A (ja)
CA (1)	CA1099633A (ja)
CH (1)	CH632164A5 (ja)
DE (1)	DE2807202C2 (ja)
DK (1)	DK78378A (ja)
FR (1)	FR2380782A1 (ja)
GB (1)	GB1546027A (ja)
IE (1)	IE46409B1 (ja)
IL (1)	IL54063A0 (ja)
IT (1)	IT1092337B (ja)
LU (1)	LU79090A1 (ja)
NL (1)	NL189281C (ja)
NZ (1)	NZ186489A (ja)
PH (1)	PH13858A (ja)
SE (1)	SE444647B (ja)
ZA (1)	ZA78890B (ja)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2732587A1 (de) *	1976-09-22	1978-03-23	Bach Jean Francois	Polypeptid mit thymischer wirksamkeit
US4148788A (en) *	1978-01-23	1979-04-10	Hoffmann-La Roche Inc.	Synthesis of thymosin α1
US4239498A (en) *	1978-11-27	1980-12-16	Rule Allyn H	Method of preparing thymic factors and composition
US4264571A (en) *	1979-01-22	1981-04-28	George Washington University	Radioimmunoassay of thymosin α1
EP0057702A1 (en) *	1980-08-08	1982-08-18	Rak-A-Van Pty Limited	Improved racking
US4427783A (en)	1981-12-14	1984-01-24	Hoffmann-La Roche Inc.	Immunoassay of thymosin α1
US4389343A (en) *	1981-12-24	1983-06-21	Hoffmann-La Roche Inc.	Immunopotentiating peptides from thymus
US4388234A (en) *	1981-12-28	1983-06-14	Hoffmann-La Roche Inc.	Peptide isolation
US4614731A (en) *	1983-09-15	1986-09-30	Hoffmann-La Roche Inc.	Peptide having immunopotentiating activity similar to thymosin alpha1
US4659694A (en) *	1983-10-27	1987-04-21	Hoffmann-La Roche Inc.	Prothymosin alpha
US4814434A (en) *	1984-02-03	1989-03-21	Ventres Laboratories, Inc.	Inducer of T-suppressor cells
DE3633651A1 (de) *	1986-10-03	1988-04-14	Alfred Dr Dick	Verwendung von fraktionen aus thymus- und milzextrakten zur behandlung der psoriasis
US5273963A (en) *	1991-03-29	1993-12-28	The George Washington University	Compositions and methods for treating small cell and nonsmall cell lung cancers
JP4404866B2 (ja)	2006-03-03	2010-01-27	ゼライス株式会社	エンドトキシン含有量を低減したゼラチンの製造方法および低エンドトキシンゼラチン

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4002602A (en) *	1974-03-11	1977-01-11	Gideon Goldstein	Ubiquitous immunopoietic polypeptide (UBIP) and methods
US4010148A (en) *	1975-05-12	1977-03-01	Board Of Regents Of The University Of Texas System	Purified thymosin and process
US4002740A (en) *	1975-08-21	1977-01-11	Gideon Goldstein	Tridecapeptide compositions and methods

1977
- 1977-02-22 US US05/770,480 patent/US4082737A/en not_active Expired - Lifetime
1978
- 1978-01-18 CH CH51178A patent/CH632164A5/de not_active IP Right Cessation
- 1978-01-30 IT IT19791/78A patent/IT1092337B/it active
- 1978-02-06 CA CA296,326A patent/CA1099633A/en not_active Expired
- 1978-02-07 NL NLAANVRAGE7801422,A patent/NL189281C/xx not_active IP Right Cessation
- 1978-02-15 ZA ZA00780890A patent/ZA78890B/xx unknown
- 1978-02-15 NZ NZ186489A patent/NZ186489A/xx unknown
- 1978-02-16 IL IL54063A patent/IL54063A0/xx not_active IP Right Cessation
- 1978-02-16 IE IE335/78A patent/IE46409B1/en not_active IP Right Cessation
- 1978-02-16 AU AU33343/78A patent/AU516946B2/en not_active Expired
- 1978-02-20 DE DE2807202A patent/DE2807202C2/de not_active Expired
- 1978-02-20 LU LU79090A patent/LU79090A1/xx unknown
- 1978-02-20 JP JP1774678A patent/JPS53104719A/ja active Granted
- 1978-02-20 FR FR7804718A patent/FR2380782A1/fr active Granted
- 1978-02-21 SE SE7802014A patent/SE444647B/sv unknown
- 1978-02-21 PH PH20803A patent/PH13858A/en unknown
- 1978-02-21 DK DK78378A patent/DK78378A/da unknown
- 1978-02-21 AT AT0124578A patent/AT363177B/de not_active IP Right Cessation
- 1978-02-21 BE BE185321A patent/BE864139A/xx not_active IP Right Cessation
- 1978-02-21 GB GB6845/78A patent/GB1546027A/en not_active Expired

Also Published As

Publication number	Publication date
DK78378A (da)	1978-08-23
GB1546027A (en)	1979-05-16
DE2807202A1 (de)	1978-08-24
ATA124578A (de)	1980-12-15
NL7801422A (nl)	1978-08-24
NL189281B (nl)	1992-10-01
IT7819791A0 (it)	1978-01-30
LU79090A1 (fr)	1979-05-25
ZA78890B (en)	1979-01-31
BE864139A (fr)	1978-08-21
DE2807202C2 (de)	1987-04-02
CA1099633A (en)	1981-04-21
FR2380782A1 (fr)	1978-09-15
AT363177B (de)	1981-07-10
IT1092337B (it)	1985-07-06
IE46409B1 (en)	1983-06-01
JPS618806B2 (ja)	1986-03-18
CH632164A5 (de)	1982-09-30
PH13858A (en)	1980-10-22
FR2380782B1 (ja)	1980-01-18
US4082737A (en)	1978-04-04
AU516946B2 (en)	1981-07-02
AU3334378A (en)	1979-08-23
IL54063A0 (en)	1978-04-30
IE780335L (en)	1978-08-22
SE7802014L (sv)	1978-08-23
NL189281C (nl)	1993-03-01
SE444647B (sv)	1986-04-28
NZ186489A (en)	1981-01-23

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