JPS5233662A - Preparation of n2-naphthalenesulfonyl-alginamides and acid addition sa lts thereof - Google Patents
Preparation of n2-naphthalenesulfonyl-alginamides and acid addition sa lts thereofInfo
- Publication number
- JPS5233662A JPS5233662A JP50110242A JP11024275A JPS5233662A JP S5233662 A JPS5233662 A JP S5233662A JP 50110242 A JP50110242 A JP 50110242A JP 11024275 A JP11024275 A JP 11024275A JP S5233662 A JPS5233662 A JP S5233662A
- Authority
- JP
- Japan
- Prior art keywords
- alginamides
- naphthalenesulfonyl
- lts
- preparation
- acid addition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002253 acid Substances 0.000 title 1
- 239000003146 anticoagulant agent Substances 0.000 abstract 1
- 239000004019 antithrombin Substances 0.000 abstract 1
- 229960004676 antithrombotic agent Drugs 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000008030 elimination Effects 0.000 abstract 1
- 238000003379 elimination reaction Methods 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Landscapes
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Abstract
PURPOSE: Title compounds having anti-thrombin activity and useful as diagnastic reagent and antithrombotic agent are prepared by the elimination of the substituent groups of the corresponding NG-substd. derivatives.
COPYRIGHT: (C)1977,JPO&Japio
Priority Applications (22)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP50110242A JPS5913501B2 (en) | 1975-09-11 | 1975-09-11 | Method for producing N↑2-naphthalenesulfonylargininamides or acid addition salts thereof |
US05/703,704 US4069323A (en) | 1974-11-08 | 1976-07-08 | N2 -substituted-L-arginine derivatives and the pharmaceutically acceptable acid addition salts thereof |
CA257,283A CA1106851A (en) | 1975-08-08 | 1976-07-19 | N.sup.2-substituted-l-arginine derivatives and the pharmaceutically acceptable acid addition salts thereof |
CH996676A CH632243A5 (en) | 1975-08-08 | 1976-08-04 | Process for preparing N2-substituted L-arginine amides |
NL7608784A NL7608784A (en) | 1975-08-08 | 1976-08-06 | N2 SUBSTITUTED L-ARGININE DERIVATIVES AND METHOD OF PREPARATION. |
DK357876A DK357876A (en) | 1975-08-08 | 1976-08-06 | PROCEDURE FOR THE PREPARATION OF ARGIN INDIVIDUALS |
DE2635548A DE2635548C2 (en) | 1975-08-08 | 1976-08-06 | N → 2 → -substituted L-arginine esters and amides, their preparation and use |
GB32910/76A GB1530667A (en) | 1975-08-08 | 1976-08-06 | N2-substituted argininamides |
NO762744A NO762744L (en) | 1975-08-08 | 1976-08-06 | |
FR7624336A FR2320088A1 (en) | 1975-08-08 | 1976-08-09 | ARGININE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USES |
SE7608791A SE428014B (en) | 1975-08-08 | 1976-08-25 | ANALOGY PROCEDURE FOR PREPARING N? 722 SUBSTITUTED L-ARGIN INGREDIENTS |
US05/760,929 US4101653A (en) | 1974-11-08 | 1977-01-19 | N2 -arylsulfonyl-argininamides and the pharmaceutically acceptable salts thereof |
US05/760,745 US4066773A (en) | 1974-11-08 | 1977-01-19 | N2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof |
US05/776,195 US4097591A (en) | 1974-11-08 | 1977-03-10 | N2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof |
US05/804,368 US4131673A (en) | 1974-11-08 | 1977-06-07 | N2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof |
US05/819,872 US4133880A (en) | 1974-11-08 | 1977-07-28 | N2 -Substituted-L-arginine derivatives and the pharmaceutically acceptable acid addition salts thereof |
US05/844,188 US4117127A (en) | 1974-11-08 | 1977-10-21 | N2 -Arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof |
US05/902,855 US4173630A (en) | 1974-11-08 | 1978-05-04 | N2 Arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof |
US05/938,711 US4201863A (en) | 1974-11-08 | 1978-08-31 | N2 -Arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof |
UA2814248A UA8371A1 (en) | 1974-11-08 | 1979-08-30 | Process for the preparation of n2-arylsulfonyl-l-argininamides |
CH379781A CH628880A5 (en) | 1975-08-08 | 1981-06-10 | Process for the preparation of N2-substituted L-arginine esters and their salts with acids |
CH379881A CH629764A5 (en) | 1975-08-08 | 1981-06-10 | Process for the preparation of N2-substituted L-argininamides |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP50110242A JPS5913501B2 (en) | 1975-09-11 | 1975-09-11 | Method for producing N↑2-naphthalenesulfonylargininamides or acid addition salts thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5233662A true JPS5233662A (en) | 1977-03-14 |
JPS5913501B2 JPS5913501B2 (en) | 1984-03-30 |
Family
ID=14530699
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP50110242A Expired JPS5913501B2 (en) | 1974-11-08 | 1975-09-11 | Method for producing N↑2-naphthalenesulfonylargininamides or acid addition salts thereof |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5913501B2 (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4960376A (en) * | 1989-06-22 | 1990-10-02 | Container Corporation Of America | Apparatus for making a plastic container with integral handling ring |
US4992230A (en) * | 1988-07-21 | 1991-02-12 | Sabel Plastechs, Inc. | Method for making a hollow polyethylene terephthalate blow molded article with an integral external projection such as a handle |
US4993931A (en) * | 1988-07-21 | 1991-02-19 | Sabel Plastechs, Inc. | Apparatus for making a hollow polyethylene terephthalate blow molded article with an integral external projection such as a handle |
-
1975
- 1975-09-11 JP JP50110242A patent/JPS5913501B2/en not_active Expired
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4992230A (en) * | 1988-07-21 | 1991-02-12 | Sabel Plastechs, Inc. | Method for making a hollow polyethylene terephthalate blow molded article with an integral external projection such as a handle |
US4993931A (en) * | 1988-07-21 | 1991-02-19 | Sabel Plastechs, Inc. | Apparatus for making a hollow polyethylene terephthalate blow molded article with an integral external projection such as a handle |
US4960376A (en) * | 1989-06-22 | 1990-10-02 | Container Corporation Of America | Apparatus for making a plastic container with integral handling ring |
Also Published As
Publication number | Publication date |
---|---|
JPS5913501B2 (en) | 1984-03-30 |
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