JPS5225768A - Preparation of novel pentapeptides - Google Patents
Preparation of novel pentapeptidesInfo
- Publication number
- JPS5225768A JPS5225768A JP51103464A JP10346476A JPS5225768A JP S5225768 A JPS5225768 A JP S5225768A JP 51103464 A JP51103464 A JP 51103464A JP 10346476 A JP10346476 A JP 10346476A JP S5225768 A JPS5225768 A JP S5225768A
- Authority
- JP
- Japan
- Prior art keywords
- preparation
- residue
- pentapeptides
- glycine
- novel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000003630 glycyl group Chemical group [H]N([H])C([H])([H])C(*)=O 0.000 abstract 3
- KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 abstract 2
- QDGAVODICPCDMU-UHFFFAOYSA-N 2-amino-3-[3-[bis(2-chloroethyl)amino]phenyl]propanoic acid Chemical compound OC(=O)C(N)CC1=CC=CC(N(CCCl)CCCl)=C1 QDGAVODICPCDMU-UHFFFAOYSA-N 0.000 abstract 1
- 239000004471 Glycine Substances 0.000 abstract 1
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Natural products NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 1
- AGPKZVBTJJNPAG-WHFBIAKZSA-N L-isoleucine Chemical compound CC[C@H](C)[C@H](N)C(O)=O AGPKZVBTJJNPAG-WHFBIAKZSA-N 0.000 abstract 1
- 229930182844 L-isoleucine Natural products 0.000 abstract 1
- 125000002435 L-phenylalanyl group Chemical group O=C([*])[C@](N([H])[H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000000174 L-prolyl group Chemical group [H]N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(*)=O 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 229960000310 isoleucine Drugs 0.000 abstract 1
- WPLOVIFNBMNBPD-ATHMIXSHSA-N subtilin Chemical compound CC1SCC(NC2=O)C(=O)NC(CC(N)=O)C(=O)NC(C(=O)NC(CCCCN)C(=O)NC(C(C)CC)C(=O)NC(=C)C(=O)NC(CCCCN)C(O)=O)CSC(C)C2NC(=O)C(CC(C)C)NC(=O)C1NC(=O)C(CCC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C1NC(=O)C(=C/C)/NC(=O)C(CCC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C2NC(=O)CNC(=O)C3CCCN3C(=O)C(NC(=O)C3NC(=O)C(CC(C)C)NC(=O)C(=C)NC(=O)C(CCC(O)=O)NC(=O)C(NC(=O)C(CCCCN)NC(=O)C(N)CC=4C5=CC=CC=C5NC=4)CSC3)C(C)SC2)C(C)C)C(C)SC1)CC1=CC=CC=C1 WPLOVIFNBMNBPD-ATHMIXSHSA-N 0.000 abstract 1
- 229960004295 valine Drugs 0.000 abstract 1
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
PURPOSE: Pentapeptides of formula I(B is glycine residue with the amino group as its terminal radical;C is L-proline residue;D is L-isoleucine, L-valine, L-phenylalanine, L-lysine, or glycine residue;E is glycine or L-phenylalanine residue).
COPYRIGHT: (C)1977,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP51103464A JPS5225768A (en) | 1976-08-30 | 1976-08-30 | Preparation of novel pentapeptides |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP51103464A JPS5225768A (en) | 1976-08-30 | 1976-08-30 | Preparation of novel pentapeptides |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP48093696A Division JPS5229740B2 (en) | 1973-08-21 | 1973-08-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5225768A true JPS5225768A (en) | 1977-02-25 |
| JPS5327273B2 JPS5327273B2 (en) | 1978-08-07 |
Family
ID=14354727
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP51103464A Granted JPS5225768A (en) | 1976-08-30 | 1976-08-30 | Preparation of novel pentapeptides |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5225768A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5132119A (en) * | 1989-07-31 | 1992-07-21 | Massachusetts Institute Of Technology | Treatment of hypertrophic wound healing disorders with calcium channel blockers |
| US5569678A (en) * | 1989-07-31 | 1996-10-29 | Massachusetts Institute Of Technology | Control of wound scar production |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6218574U (en) * | 1985-07-13 | 1987-02-04 |
-
1976
- 1976-08-30 JP JP51103464A patent/JPS5225768A/en active Granted
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5132119A (en) * | 1989-07-31 | 1992-07-21 | Massachusetts Institute Of Technology | Treatment of hypertrophic wound healing disorders with calcium channel blockers |
| US5569678A (en) * | 1989-07-31 | 1996-10-29 | Massachusetts Institute Of Technology | Control of wound scar production |
| US5902609A (en) * | 1989-07-31 | 1999-05-11 | Massachusetts Institute Of Technology | Composition for the control of wound scar production |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5327273B2 (en) | 1978-08-07 |
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