JPH1133117A - Nasal administration device - Google Patents

Abstract

(57) [Problem] To stably administer a drug powder to a patient by spraying the drug powder only when a spray nozzle is inserted into a nasal cavity. SOLUTION: A medicine spraying part 4 has a shutter 14 for opening and closing the medicine powder passage 6, a shutter moving part 15 for opening the shutter 14 by being pushed by a septum 18 between nasal cavities 17, and closing the shutter 14. A chemical powder passage opening / closing mechanism 12 including a return spring 16 biasing in the direction is provided. Therefore, when the spray nozzle 7 is not inserted into the nasal cavity 17, the shutter 1 is biased by the return spring 16.
4, the powder passage 6 can be blocked, while when the spray nozzle 7 is inserted into the nasal cavity 17, the nasal septum 1
8, the shutter moving section 15 is pushed and the shutter 14 is moved.
Can be opened to communicate the chemical powder passage 6.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a nasal administration device suitable for administering a medicine powder contained in a medicine chamber to a left and right nasal cavity of a patient.

[0002]

2. Description of the Related Art In general, for patients suffering from nasal allergy or the like, a method of spraying a medicine powder (powder medicine) into a nasal cavity is employed. Also, this treatment uses a special nebulizer,
The medicine powder chamber is filled with the medicine powder, and the medicine powder is administered into the nasal cavity.

[0003] Further, as a nebulizer used for this treatment, for example, Japanese Patent Application Laid-Open No. Hei 8-243163
(Referred to as prior art) is known.

[0004] The nasal administration device in this prior art is provided on one side of the holder with a medicine powder chamber for accommodating a medicine powder, and supplies air to the medicine powder chamber with the medicine powder chamber interposed therebetween. A pump and a medicine which is provided on the opposite side of the pump with the medicine powder chamber therebetween and sprays the medicine powder in the medicine powder chamber into the nasal cavity from the left and right spray nozzles through the left and right medicine passages. It is roughly composed of a powder spraying section.

In the nasal administration device according to the prior art configured as described above, the medicine powder chamber is filled with the medicine powder, and the left and right spray nozzles of the medicine powder spray unit are inserted into the left and right nasal cavities. In this state, the pump is pressed and air is supplied from the pump to the powder chamber, whereby the powder in the powder chamber is sprayed by the air through the left and right powder passages. Spray into the nasal cavity from the nozzle to administer the medicinal powder to the patient.

[0006]

In the above-described nasal administration device according to the prior art, since the pump, the medicine powder chamber, the medicine powder passage, and the medicine powder nozzle are always in communication, the medicine powder is supplied into the medicine chamber. If the pump is accidentally pressed in the filled state, the air supplied from the pump flows into the powder chamber,
The medicine powder in the medicine powder chamber is sprayed outside from the spray nozzle via the medicine powder passage.

As a result, not only is the medicinal powder wasted, but the dose of the medicinal powder to the patient becomes unstable, and it becomes impossible to administer the prescribed amount of the medicinal powder to the patient. This leads to a problem that the reliability is lowered.

[0008] In addition, if the medicine powder is mis-sprayed as described above, it is necessary to carefully handle the nasal administration device, and thus there is a problem that handling of the nasal administration device becomes troublesome.

SUMMARY OF THE INVENTION The present invention has been made in view of the above-mentioned problems of the prior art, and an object of the present invention is to spray a medicine powder only when a spray nozzle is inserted into a nasal cavity, thereby providing the medicine powder to a patient. An object of the present invention is to provide a nasal administration device capable of stably administering.

[0010]

A nasal administration device according to the present invention is provided on one side of a holder having a medicine powder chamber for accommodating medicine powder, and one side of the holder with the medicine powder chamber interposed therebetween. A pump for supplying air to the pump, and a pump provided on the opposite side of the powder chamber with the powder chamber interposed therebetween. A chemical powder spraying section for spraying the inside.

Then, in order to solve the above-mentioned problem,
A feature of the configuration adopted by the invention of claim 1 is that the medicine powder spraying section opens the left and right medicine powder passages only when the left and right spray nozzles are inserted into the nasal cavity. The opening and closing mechanism is provided.

With this configuration, each powder passage is opened and communicated by the powder passage opening / closing mechanism only when the left and right spray nozzles are inserted into the nasal cavity. By pressing, the medicine powder in the medicine powder chamber can be sprayed into the nasal cavity from the left and right medicine powder nozzles through the left and right medicine powder passages. In other states, the powder passage opening / closing mechanism closes the left and right powder passages to restrict the ejection of the powder.

According to a second aspect of the present invention, the chemical powder passage opening / closing mechanism comprises:
Left and right shutters for opening and closing the left and right powder passages,
A shutter moving unit provided between the right spray nozzles and moved by the nasal septum located between the left and right nasal cavities to move the respective shutters in the opening direction, and a return for urging the shutters in the closing direction; And a spring.

With this configuration, when the spray nozzle is not inserted into the nasal cavity, the left and right shutters are urged in the closing direction by the return springs. It shuts off and regulates spraying of chemical powder. On the other hand, when the left and right spray nozzles are inserted into the left and right nasal cavities of the patient, the shutter moving parts provided between the spray nozzles are pushed by the nasal septum between the nasal cavities. The medicine powder can be opened in opposition to allow the left and right medicine powder passages to communicate with each other, and the medicine powder can be sprayed into the nasal cavity from the spray nozzle.

According to a third aspect of the present invention, the left and right shutters
It comprises a block body slidably provided in the left and right directions to open and close the left and right powder passages, and a pin sliding hole formed in the block body in an oblique direction. , Which is provided to be movable downward,
A pusher disposed between the right spray nozzles, and left and right sliding pins fixed to the pusher and having leading ends inserted into pin sliding holes of left and right shutters, and a return spring is provided with the pusher. Are biased in a direction to separate them from the left and right shutters.

With this configuration, when the spray nozzle is not inserted into the nasal cavity, the pusher of the shutter moving unit is located at a position separated from the shutter by the return spring. The left and right sliding pins separate the blocks engaged via the pin sliding holes from each other. As a result, the left and right powder passages are respectively blocked and blocked by the block body,
Spraying of chemical powder is regulated.

On the other hand, when the left and right spray nozzles are inserted into the left and right nasal cavities, the pusher of the shutter moving portion is pushed by the nasal septum between the nasal cavities and approaches the shutter, so that the left and right sliding are performed. The pins cause the left and right shutters to approach each other. As a result, the shutoff of the powder passage by the shutter is released, and the powder passage is opened and communicated. It can be sprayed into the nasal cavity from the right spray nozzle.

[0018]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, a nasal administration device according to an embodiment of the present invention will be described in detail with reference to FIGS.

Reference numeral 1 denotes a capsule holder serving as a holder for forming a main body of a nasal administration device and holding a capsule K described later.
The capsule holder 1 defines a capsule accommodating chamber 5 between the capsule holder 1 and a medicine powder spraying section 4 described later. In the capsule holder 1, a first piercing pin (not shown) for locating an air inlet hole in the capsule K accommodated in the capsule accommodation chamber 5 is provided below the capsule accommodation chamber 5. ) Is provided.

Reference numeral 2 denotes a pump made of a rubber material or the like provided so as to cover the outer peripheral side of the capsule holder 1.
Is a cylindrical portion 2A whose upper end is fixed to the capsule holder 1.
And a bottom portion 2B that closes a lower opening of the cylindrical portion 2A to form a bottomed cylindrical shape. The pump 2 is provided with a suction valve 3 located at the center of the bottom portion 2B. The suction valve 3 closes when air is discharged from the pump 2, and sucks air into the pump 2 from outside. Sometimes the valve opens.

Numeral 4 denotes a chemical powder spraying section connected to the upper side of the capsule holder 1. The lower side of the chemical powder spraying section 4 on the side of the capsule holder 1 is a small diameter section 4A, and the upper side is a large diameter section 4B. It has become. As shown in FIG. 2, a capsule storage chamber 5 serving as a medicine powder chamber is formed between the small diameter portion 4A and the capsule holder 1. Further, the large-diameter portion 4B has left and right chemical powder passages 6 and 6 and spray nozzles 7 and 7 to be described later.
Is provided.

Reference numerals 6 and 6 denote left and right medicine powder passages formed in the medicine spraying section 4, respectively. Each of the medicine powder passages 6 includes a branch passage 6A branched from the capsule housing chamber 5 and a branch passage 6A. 6A and a straight passage portion 6B extending linearly toward the spray nozzle 7.

Numerals 7 and 7 denote left and right spray nozzles provided in the large diameter portion 4B of the chemical powder spraying section 4. The respective spray nozzles 7 are inserted into left and right nasal cavities 17 and 17 to be described later. That
The large-diameter portion 4B protrudes from the upper end surface and has a tapered shape whose tip end side is gradually reduced in diameter. Further, each spray nozzle 7 is located at the center thereof and communicates with the linear passage portion 6B of the medicine powder passage 6 to spray the medicine powder into the nasal cavity 17.
Are formed.

Reference numeral 8 denotes a second drilling pin provided on the chemical powder spraying section 4 so as to face the first drilling pin. The base end of the second drilling pin 8 is provided so as to be slidable in the vertical direction. The distal end side is extended so as to penetrate the seal rubber 10 and the distal end is formed sharp. In addition, the moving member 9 is provided with an operation plate 1 provided on an outer surface of the chemical powder spraying unit 4 for operating the second drilling pin 8.
1, 11 (shown in FIGS. 1 and 3). The second drilling pin 8 is moved downward together with the moving member 9 toward the capsule K by moving each operation plate 11 downward, and the leading end of the second drilling pin 8 causes the air outflow hole H to enter the capsule K. Is to be drilled.

Reference numeral 12 denotes a chemical powder passage opening / closing mechanism provided in the chemical powder spraying section 4. The chemical powder passage opening / closing mechanism 12 is generally constituted by a shutter 14, a shutter moving section 15, a return spring 16, and the like, which will be described later. .

Reference numeral 13 denotes a shutter sliding space formed in the large diameter portion 4B of the chemical powder spraying section 4. The shutter sliding space 13
As shown in FIG. 2 and FIG. 3, each of the left and right ends is defined as a long rectangular parallelepiped extending in the left and right directions. Has reached. Also,
Above the shutter sliding space 13, pin insertion grooves 13A, 13A are formed between the left and right spray nozzles 7, and through which sliding pins 15B, 15B described later are movably inserted. .

Reference numerals 14 and 14 denote left and right shutters slidably disposed in the shutter sliding space 13 in the left and right directions, respectively. A short rectangular parallelepiped block body 14A sliding on
A pin sliding hole 14 is formed in the block body 14A in an oblique direction so as to gradually separate from each other from the upper side to the lower side.
B in the pin sliding hole 14B.
5B is slidably inserted.

Reference numeral 15 denotes a shutter moving unit provided between the left and right spray nozzles 7, 7, which moves vertically between the left and right spray nozzles 7, 7. Flat pusher 1 that moves in the directions indicated by arrows A and B
Left and right sliding members 5A and 5A whose base end is fixed to the lower surface of the pusher 15A and whose front end extends obliquely so as to gradually separate from the left and right shutters 14 through the pin insertion grooves 13A. The pins 15B, 15B and the respective sliding pins 15
B and a positioning pin 15C extending downward from the lower surface of the pusher 15A. Further, the tip side of the positioning pin 15C is engaged with the chemical powder spraying part 4, thereby defining the height position of the shutter moving part 15 with respect to the chemical powder spraying part 4. Further, the left and right sliding pins 15B, 15B are formed with the same inclination angle as the pin sliding holes 14B, 14B of the left and right shutters 14, 14, and slide into the pin sliding holes 14B, 14B. Is inserted as possible.

Reference numeral 16 denotes a chemical powder spraying unit 4 and a pusher 15A which are located on the outer peripheral side of a positioning pin 15C of the shutter moving unit 15.
The return spring 16 urges the pusher 15A in the direction of separating the pusher 15A from the left and right shutters 14, 14, that is, the shutter moving unit 15 in the direction of arrow A. . In this way, the return spring 16 is
5 is urged in the direction of arrow A, so that the left and right sliding pins 1
The left and right shutters 14, 14 are urged in the direction of arrow C, which is the closing direction, via 5B, 15B.

When the left and right spray nozzles 7, 7 are not inserted into the nasal cavity 17, the chemical powder passage opening / closing mechanism 12 configured as described above uses a return spring 16 as shown in FIG. The moving unit 15 has been moved in the direction of arrow A. As a result, the sliding pins 15B of the shutter moving unit 15 are moved through the pin sliding holes 14B to the left and right shutters 1B.
4 and 14 are moved in the direction of the arrow C away from each other.
6 is closed and shut off.

On the other hand, as shown in FIG. 4, when the left and right spray nozzles 7, 7 are inserted into the nasal cavity 17,
The nasal septum 18 located between the abutments 7 contacts the pusher 15A of the shutter moving unit 15, and pushes the pusher 15A in the direction of arrow B. As a result, the left and right sliding pins 15B are inserted deeply into the pin sliding holes 14B of the left and right shutters 14 together with the pushers 15A.
14 move in the direction of arrow D so as to approach each other. As a result, the left and right shutters 14 and 14 are separated from the left and right powder passages 6 and 6 to release the cutoff of the respective powder passages 6 and open and communicate the powder passages 6.

The dispenser for nasal cavity according to the present embodiment has the above-described configuration. Next, the operation of the dispenser will be described.

First, a description will be given of a preparation operation until the air inflow hole and the air outflow hole H are formed in the capsule K. First, the capsule K is mounted on the capsule holder 1 and an air inflow hole is formed below the capsule K with a first piercing pin. An air outflow hole H is formed on the upper side of the capsule K by the piercing pin 8.

In this state, since the left and right spray nozzles 7 are not inserted into the nasal cavity 17, the left and right powder passages 6 and 6 are closed and blocked by the respective shutters 14. For this reason, even if the patient presses the pump 2 by mistake, the medicine powder in the capsule K can be prevented from being sprayed from each spray nozzle 7.

Next, a medication operation for spraying the medicine powder in the perforated capsule K into the left and right nasal cavities 17, 17 of the patient will be described.

First, as shown in FIG. 4, when the left and right spray nozzles 7, 7 are inserted into the left and right nasal cavities 17, 17 of the patient, a shutter moving section 15 provided between the spray nozzles 7 is provided.
Abuts on the nasal septum 18 between the nasal cavities 17 and is pushed in the direction of arrow B. As a result, the left and right shutters 14 and 14 move in the direction of arrow D, and the cutoff of the left and right powder passages 6 is released, so that the respective powder passages 6 are opened and communicated. be able to.

Then, by crushing the pump 2 in this state, an air flow is generated from the pump 2, and this air flows into the capsule K into the capsule storage chamber 5. As a result, the air that has flowed into the capsule K becomes the air mixed with the chemical powder by stirring the chemical powder, so that the air mixed with the chemical powder is passed through the air outflow hole H and the left and right chemical powder passages 6,6. By spraying from the spray ports 7A of the left and right spray nozzles 7, 7, the medicine powder can be simultaneously administered to the left and right nasal cavities 17, 17 of the patient.

Therefore, according to the present embodiment, the spray nozzle 7
2 is not inserted into the nasal cavity 17, as shown in FIG.
4, the left and right powder passages 6, 6 can be closed and blocked. Therefore, even if the pump 2 is erroneously pressed after forming the air outflow hole H or the like in the capsule K,
It is possible to restrict the chemical powder in the capsule K from being ejected from the spray nozzle 7 to the outside.

On the other hand, the left and right spray nozzles 7,
When the shutter 14 is inserted into the shutters 7 and 17, the shutter moving section 15 is pushed by the nasal septum 18 so that the shutter 14 is moved.
Of the powder passage 6 is released, and the respective powder passages 6 can be opened and communicated. Therefore, by pressing the pump 2, the powder in the capsule K is sprayed from the left and right powder nozzles 7, 7 into the nasal cavity 17, 17 through the left and right powder passages 6, 6. Can be.

As a result, the medicine powder in the capsule K can be prevented from being unnecessarily ejected during the preparation operation, and the medicine powder can be sprayed from the spray nozzle 7 when the spray nozzle 7 is inserted into the nasal cavity 17. The medicine powder in the capsule K can be stably supplied to the patient. As a result, the prescribed amount of the medicinal powder can be administered to the patient, so that the efficacy of the medicinal powder can be enhanced, and the reliability of the nasal administration device can be improved.

Further, since the medicine powder in the capsule K can be prevented from being ejected to the outside, the pump 2 and the like can be easily grasped when the nasal administration device is held by hand, and the nasal administration device can be easily held. Can be easily handled.

Further, a shutter moving portion 15 is provided between the left and right spray nozzles 7, 7, and the medicine moving passage 6 is moved by pushing the shutter moving portion 15 by a septum 18 located between the nasal cavities 17. I am trying to open it. Therefore, only when the spray nozzle 7 is inserted sufficiently deep into the nasal cavity 17, the medicine powder passage 6 can be opened and the medicine powder can be sprayed, so that the efficiency of sucking the medicine powder can be increased.

In this embodiment, the chemical powder passage opening / closing mechanism 12 is used.
Block body 1 that can slide left and right shutters 14
4A and the like, and the powder powder passage 6 is opened and closed by bringing each block body 14A closer to and away from each other. However, the present invention is not limited to this, and other members such as a flap valve body may be used. It is good also as a structure which opens and closes a chemical | medical powder channel | path by using.

Further, in the embodiment, the capsule accommodation chamber 5 for accommodating the capsule K filled with the medicine powder has been described as an example of the medicine powder chamber. It may be configured to fill directly.

[0045]

As described in detail above, according to the first aspect of the present invention, the left and right powder passages are opened and closed by the powder passage opening / closing mechanism only when the left and right spray nozzles are inserted into the nasal cavity. Since the pump can be opened and connected, the powder in the powder chamber is sprayed into the nasal cavity from the left and right powder nozzles through the left and right powder passages by pressing the pump in this state. Can be. In other states, the left and right powder passages can be closed by the powder passage opening / closing mechanism to restrict the ejection of the powder.

This prevents the powder from being ejected to the outside, makes it possible to stably supply the powder in the powder chamber to the patient, and to administer a prescribed amount of the powder to the patient. Therefore, the efficacy of the medicinal powder can be enhanced, and the reliability of the nasal administration device can be improved. Further, handling of the nasal administration device can be facilitated.

According to the second aspect of the present invention, when the spray nozzle is not inserted into the nasal cavity, the return spring is used to move the spray nozzle to the left and right.
Since the right shutter is biased in the closing direction, the left and right medicine powder passages can be shut off by the respective shutters, and the spraying of the medicine powder can be restricted. On the other hand, when the left and right spray nozzles are inserted into the left and right nasal cavities of the patient, the nasal septum is used by pushing the shutter moving part provided between the spray nozzles by the nasal septum between the nasal cavities. The medicine powder passage can communicate with the medicine powder, and the medicine powder can be sprayed into the nasal cavity from the left and right spray nozzles. Therefore, the medicine powder passage can be opened and closed without performing a special operation, and handling can be facilitated.

According to the third aspect of the present invention, when the spray nozzle is not inserted into the nasal cavity, the pusher of the shutter moving unit is disposed at a position separated from the shutter by the return spring, so that it is provided in the shutter moving unit. The left and right shutters can be separated from each other through the pin sliding holes by the left and right sliding pins. Thereby, the left and right chemical powder passages can be respectively closed and blocked by the shutter, and the spraying of the chemical powder can be regulated.

On the other hand, when the left and right spray nozzles are inserted into the left and right nasal cavities, the pusher of the shutter moving section is pushed by the septum of the nose to approach the shutter.
The right shutter can be brought closer to each other by the left and right sliding pins. Thus, the shutter of the powder passage by the shutter can be released, and the powder passage can be opened and communicated. By pressing the pump in this state, the powder in the powder chamber can be left and right. Through the powder passage, it can be sprayed into the nasal cavity from the left and right spray nozzles.

[Brief description of the drawings]

FIG. 1 is an external view showing a nasal administration device according to an embodiment of the present invention.

FIG. 2 is an enlarged vertical sectional view of a main part showing a chemical powder spraying unit.

FIG. 3 is a cross-sectional view of the chemical powder spraying section as viewed from a direction indicated by arrows III-III in FIG.

FIG. 4 is a longitudinal sectional view showing a state in which the left and right spray nozzles are inserted into the left and right nasal cavities to spray the medicinal powder in the capsule.

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 1 Capsule holder (holder) 2 Pump 4 Chemical powder spraying part 5 Capsule accommodation hole (chemical powder chamber) 6 Chemical powder passage 7 Spray nozzle 12 Chemical powder passage opening / closing mechanism 14 Shutter 14A Block body 14B Pin sliding hole 15 Shutter moving part 15A Pusher 15B sliding pin 16 return spring 17 nasal cavity 18 nasal septum

Continued on the front page (72) Inventor Shigemi Nakamura 1370 Onna, Atsugi-shi, Kanagawa Prefecture Inside Unisia Gex Co., Ltd. ) Inventor Akira Yanagawa 5-3 Fujimigaoka, Tsuzuki-ku, Yokohama-shi, Kanagawa

Claims (3)

[Claims] 1. A holder having a medicine powder chamber for accommodating medicine powder, a pump provided on one side of the holder with the medicine powder chamber interposed therebetween, and supplying air to the medicine powder chamber, It is provided on the opposite side of the pump with the powder in it,
A nasal cavity dispenser comprising: a right and left spray nozzle for spraying into the nasal cavity from a left and right spray nozzle via a right powder passage; A drug delivery device for nasal cavity, characterized in that a medicine powder passage opening / closing mechanism for opening the left and right medicine powder passages only when inserted into the nasal cavity is provided. 2. The medicine passage opening / closing mechanism is provided between left and right shutters for opening and closing the left and right medicine passages, and left and right spray nozzles, and is located between the left and right nasal cavities. 2. The nasal cavity dispenser according to claim 1, further comprising a shutter moving unit that moves each of the shutters in the opening direction by being pushed by the nasal septum, and a return spring that urges the shutters in the closing direction. 3. The left and right shutters are provided so as to be slidable in the left and right directions and open and close the left and right chemical powder passages, and a pin slide penetrating the block body in an oblique direction. A moving hole, wherein the shutter moving portion is provided movably upward and downward, and is disposed between the left and right spray nozzles so as to contact the nasal septum; The left and right sliding pins are inserted into the pin sliding holes of the left and right shutters, and the return spring is disposed so as to bias the pusher in a direction for separating the pushers from the left and right shutters. The nasal administration device according to claim 2, which is configured.