JPH11147803A - Composition for preventing pine wilt - Google Patents

Abstract

(57) Abstract: Composition for preventing pine wilt [Solution] 5-chloro-N- [2- {2,3-dimethyl-4- (2-ethoxyethyl) phenoxy} ethyl]
This is a composition containing -6-ethyl-4-pyrimidinamine (common name: pyrimidifen) as an active ingredient. The surfactant is added to improve solubilization in water and promote the effect of the active ingredient. Composition.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

TECHNICAL FIELD The present invention relates to a composition for controlling pine wilt by controlling pine wood nematodes.

[0002]

2. Description of the Related Art At present, pine is polluted by so-called "pine worms" in most areas except Hokkaido and a part of Tohoku, and pine wilt is severe, so it is necessary to take measures to prevent it. ing. As a result of elucidating the cause of such pine wilt, it was revealed that pine wilt is a dwarf disease caused by the proliferation of pine wood nematodes, which are vector insects of the pine sawyer. Therefore,
On the other hand, aerial spraying of insecticides has been carried out on a large scale in order to control pine wood pest beetles, the vector insect, P. japonicus, which is achieving some success in preventing pine wilt. However, it is necessary to carry out such aerial application of pesticides in consideration of problems such as human toxicity and environmental pollution, and such practice requires caution. Therefore, separately from such collective control, in order to control the pine wood nematode that invades the pine tree body and inflicts on each tree, an effective chemical is embedded in the pine tree trunk, injected, or absorbed from the root. Development of so-called single tree control technology has also been attempted. So far, compounds such as transmorantel tartrate and mesulfenphos have been shown to be effective in inhibiting the growth of pine wood nematodes.

[0003]

DISCLOSURE OF THE INVENTION The present invention seeks to find a compound which is more excellent in controlling pine wood nematodes under the present circumstances where the development of a drug for preventing pine wilt as described above has been demanded, and makes the compound effective. An object of the present invention is to develop a composition for preventing pine wilt used as a component.

[0004]

Means for Solving the Problems The present inventors have conducted intensive studies in order to solve the above-mentioned problems, and as a result, have found that a composition containing a compound having insecticidal and acaricidal activity as an active ingredient in agricultural and horticultural medicine situations. Thus, the present invention was found to be effective in preventing pine wilt, and completed the present invention. This will be described in detail below.

As an active ingredient of the composition for preventing pine wilt of the present invention, the following formula (I)

[0006]

Embedded image Can be mentioned.

The compound represented by the formula (I) is a compound of the formula 5-chloro-N- [2- {2,3-dimethyl-4- (2-ethoxyethyl) phenoxy} ethyl] -6-ethyl-4-pyri Midinamine (common name: pyrimidifen).

BEST MODE FOR CARRYING OUT THE INVENTION The compound represented by the above formula (I) is known as a compound having an excellent insecticidal and acaricidal activity ("The Pesticide Manual". Tenth Edition 1994. Briiti).
sh Crop Protection Council, The Royal Society of
Chemistry).

The compound represented by the formula (I) is disclosed in
-67.

The method of using the above compound in the present invention is as follows:
Although it is possible to use it alone, it is usually blended with a solid carrier, a solvent, a surfactant, an auxiliary agent, etc. by a conventional method to prepare a liquid such as an emulsion, a solution, an emulsion, an aqueous or oily suspension. Formulation into solids such as powders, powders, granules, tablets, wedges, wires, spheres, almonds, dice, cylinders, prisms, etc. It is preferable to use them.

[0010] Among these various dosage forms, the above-mentioned compounds, particularly preferred forms of use, include (1) a method of dissolving pyrimidifen and a nonionic surfactant and / or an anionic surfactant in a solvent and then adding water. Therefore, a composition for preventing pine wilt which has improved solubility of pyrimidifen in water and has excellent dispersibility in a tree, and (2) pyrimidifen, a nonionic surfactant and / or an anionic surfactant are required. A composition for preventing pine wilt which is excellent in dispersibility in a tree and has improved solubility in water of pyrimidifen dissolved in a solvent and mixed with a solid carrier.

According to claim 3 and (2), "pyrimidifen and a nonionic surfactant and / or anionic surfactant are dissolved in a solvent if necessary and mixed with a solid carrier to prevent dying. The term “mixed with a solid carrier” as used in the term “composition for solid” refers not only to mixing, but also to mixing the solid into various forms such as granules, tablets, wettable powders, etc. It includes molding into a mold and dissolving it in a very small amount of water such as sap to prepare a formulation in which pyrimidifen is rapidly dispersed in the tree.

The components of the composition of the present invention are preferably 0.01 to 20 parts by weight, more preferably 0.1 to 10 parts by weight, and 0.5 to 30 parts by weight of a surfactant, preferably the active ingredient. Has 1
10 to 10 parts by weight, 5 to 95 parts by weight of a solvent, preferably 10 to 10 parts by weight.
To 80 parts by weight, water is 0 to 95 parts by weight, preferably 20 to
80 parts by weight may be arbitrarily combined or the active ingredient may be used in an amount of 0.01 to 20 parts by weight, preferably 0.1 to 10 parts by weight, and a surfactant of 1 to 50 parts by weight, suitably 10 to 10 parts by weight. 3
0 parts by weight, 5 to 90 parts by weight of solid carrier, preferably 10 parts by weight
７０70 parts by weight are arbitrarily combined.

As the surfactant, any of generally known anionic surfactants, cationic surfactants, nonionic surfactants and amphoteric surfactants may be used. Alternatively, nonionic surfactants are preferred. Examples of the anionic surfactant include dialkyl sulfosuccinate salts, alkyl sulfate salts, alkane sulfonic acid salts, alkyl benzene sulfonic acid salts, alkyl phosphate ester salts, N-acyl sarcosine salts and N- Acylalanine salts can be mentioned. Examples of nonionic surfactants include polyoxyethylene alkylamides, polyoxyethylene alkylamines, polyoxyethylene aryl aryl ethers, condensates of polyoxyethylene polyoxypropylene, polyoxyethylene castor oils, and polyoxyethylene cured castors. Oils, polyoxyethylene alkyl ethers, polyoxyethylene alkyl aryl ethers, polyoxyethylene alkyl aryl ether formaldehyde condensates, polyethylene glycol fatty acid esters, polyoxyethylene polyoxypropylene alkyl ethers, sorbitan fatty acid esters, poly Oxyethylene sorbitan fatty acid esters, glycerin fatty acid esters, sucrose fatty acid esters, and propylene glycol monofatty acid esters Mention may be made of Le acids.

As the solvent, methanol, ethanol,
Alcohols such as propyl alcohol, isopropyl alcohol and n-hexanol; ethylene glycol, propylene glycol, diethylene glycol,
Glycols such as 1,3-butylene glycol and isoprene glycol; ketones such as acetone, cyclohexanone and isophorone; nitriles such as acetonitrile; ethers such as tetrahydrofuran, dioxane and isopropyl ether; toluene, xylene and methyl Aromatic hydrocarbons such as naphthalene; N-
N such as methylpyrrolidone, N-octylpyrrolidone
-Alkylpyrrolidones; amides such as dimethylformamide and dimethylacetamide; sulfoxides such as dimethylsulfoxide; halogenated hydrocarbons such as chloroform, carbon tetrachloride, perchloroethylene and trichloroethane; kerosene, mineral oil, animal and vegetable oils And hydrocarbons such as ethyl acetate, ethylene glycol acetate, dibutyl maleate, and the like, preferably alcohols, glycols, ketones, N-alkylpyrrolidones, amides, or the like. Aromatic hydrocarbons.

Examples of the solid carrier include sugars such as galactose, glucose, sugar and lactose; starch derivatives such as dextrin and α-starch; celluloses such as soda salt of carboxymethylcellulose and soda salt of carboxypropylcellulose. Derivatives; polymers such as polyvinyl alcohol, polyvinylpyrrolidone and sodium polyacrylate; glycols such as polyethylene glycol and polypropylene glycol; gums such as gum arabic and xanthan gum; lignins such as lignin and sodium ligninsulfonate; talc,
Minerals such as bentonite, clay, kaolin, diatomaceous earth, white carbon, vermiculite, slaked lime, silica sand; inorganic substances such as ammonium sulfate, potassium chloride, potassium iodide, sodium carbonate, sodium hydrogen carbonate; or urea Organic substances and the like can be mentioned.

Examples of auxiliary agents include ordinary agricultural chemicals such as potency enhancers such as piperonyl butoxide and triphenyl phosphate, various ultraviolet inhibitors, stabilizers such as pH regulators and antioxidants, and dye binders. Those which can be blended therein.

When applied to pine, the application rate of the composition of the present invention can be appropriately changed depending on the purpose, timing, age, damage situation and the like. For application, a method can be employed in which a hole is made in the pine tree trunk by injection or boring, and the composition of the present invention is embedded in the hole, or natural injection and / or pressure injection is performed.

Next, the present invention will be described more specifically with reference to Reference Examples and Examples.

[0019]

Examples and Comparative Examples:
4. The pine wood nematode agent of Comparative Example 1 (2%) was prepared. Hereinafter, parts by weight are shown.

Active ingredient (active ingredient) 10.0 Cyclohexanone 70.0 NE2609 ^* 20.0 Water 400.0 Total 500.0 *: Polyoxyethylene tristyryl phenyl ether; manufactured by Nippon Emulsifier Co., Ltd. (Preparation method) The active ingredient was dissolved in cyclohexanone with stirring, and then NE2609 was added and mixed to obtain an emulsified stock solution (10%). A predetermined amount of water was weighed in a separate container, and the obtained emulsified stock solution was added thereto while stirring with a stirrer to obtain a pine wood nematode agent (2%).

The active ingredient was charged as an active ingredient in a pine wood nematode agent by converting it to a purity of 2%, and the remainder was corrected with cyclohexanone. The active ingredients contained in the preparations of the respective examples are shown in Table 1. Next, the present invention will be described more specifically with reference to examples.

Efficacy against pine wood nematode in the chemical immersion method Botrytis cinerea (Botr) in potato dextrose medium
After cultivating the pine wood nematode cultivated with ytis cinerea) as a feed, 10 ml of sterilized water is added thereto, and the pine wood nematode is scraped off.
1 was adjusted. 3 ml of this nematode suspension
Into a vial, so that the drug has a predetermined concentration in it,
1 ml of a drug diluent was added and mixed. Predetermined time 25 ℃
After standing, the writhing rate was determined by the following formula using a microscope.

[0023] i) No effect: Living normally ii) Death: Transparent or no movement iii) Agony: Tuna rolled, tail swirled, deformed Result Are shown in Table 1.

(As a comparative example, the activity of morantel oxalate is mentioned.)

[0025]

[Table 1] Efficacy test results for pine wood nematodes One day later Compound concentration (ppm) Agony insect (%) Example 1 5-chloro-N- [2- {2,3 10.0 100-dimethyl-4- (2-ethoxy1.0100 ethyl) phenoxy} ethyl] -0.1100 6-ethyl-4- Pyrimidinami 0.01 75 (generic name: pyrimidifen) Comparative Example 1 Oxalic acid Morantel 10.0 90 1.0 30

[0026]

The compound which is the active ingredient of the composition of the present invention exhibits excellent anti-pinewood nematode activity at a low dose, and the composition of the present invention containing the active ingredient is prepared by adding a surfactant. The effect of the active ingredient is promoted by improving the solubility in water, and is extremely effective as an agent for preventing pine wilt of pine trees.

 ──────────────────────────────────────────────────の Continued on the front page (72) Inventor Reiji Ichinose 1041 Yasu, Yasu-cho, Yasu-gun, Shiga Prefecture Sankyo Stock Company In-house

Claims (7)

[Claims] (1) 5-chloro-N- [2- {2,3-dimethyl-4- (2-ethoxyethyl) phenoxy} ethyl]
A composition for preventing pine wilt which contains -6-ethyl-4-pyrimidinamine (pyrimidifen) as an active ingredient. 2. The compound of claim 1 and a nonionic surfactant and / or an anionic surfactant are dissolved in a solvent, and then water is added to improve the solubility of the compound in water. A composition for preventing pine wilt which is excellent in dispersibility in a tree. 3. The dispersibility of the compound according to claim 1 and a nonionic surfactant and / or anionic surfactant dissolved in a solvent if necessary and mixed with a solid carrier in a tree. Excellent pine wilt prevention composition. 4. Nonionic surfactants such as polyoxyethylene alkylamides, polyoxyethylene alkylamines, polyoxyethylene aryl aryl ethers, condensates of polyoxyethylene polyoxypropylene, polyoxyethylene castor oils and polyoxyethylene Ethylene hydrogenated castor oils, polyoxyethylene alkyl ethers,
Polyoxyethylene alkyl aryl ethers, polyoxyethylene alkyl aryl ether formaldehyde condensates, polyethylene glycol fatty acid esters, polyoxyethylene polyoxypropylene alkyl ethers, sorbitan fatty acid esters, polyoxyethylene sorbitan fatty acid esters, glycerin fatty acid esters 4. The composition according to claim 2 or 3, comprising at least one selected from the group consisting of sucrose fatty acid esters, propylene glycol monofatty acid esters, and the polyalkylene oxide-based surfactant. A composition for preventing pine wilt. 5. Salts of dialkyl sulfosuccinates, salts of alkyl sulfates as anionic surfactants,
Claims: It contains at least one or more selected from the group consisting of salts of alkanesulfonic acid, salts of alkylbenzenesulfonic acid, salts of alkylphosphate esters, N-acylsarcosine salts and N-acylalanine salts. The composition for preventing pine wilt according to claim 2 or 3. 6. An alcohol as a solvent; a glycol;
Ketones; nitriles; ethers; aromatic hydrocarbons; amides; sulfoxides; halogenated hydrocarbons; hydrocarbons; esters; and at least one member selected from the group consisting of N-alkylpyrrolidone. The composition for preventing pine wilt according to claim 2 or 3, which comprises: 7. As a solid carrier, at least one selected from the group consisting of sugars, starch derivatives, cellulose derivatives, water-soluble polymers, glycols, gums, lignins, mineral substances, inorganic substances, and organic substances. The composition for preventing pine wilt according to claim 3, comprising: