JPH11123242A - Simplified fluid replacing device - Google Patents

Abstract

PROBLEM TO BE SOLVED: To replace fluid in a simple way while conducting blood dialysis. SOLUTION: A device comprises a blood circulation circuit to take blood of a patient out of his body to be circulated, and a fluid replacement circuit connected to the circulation circuit to replace fluid, the blood circulation circuit is connected to a conduit, it comprises a patient artery connection part 1, an artery side upstream part, a first liquid feed means, an artery side downstream part, a blood processing unit, a veneous part, and a patient vein connection part 9 disposed in blood flowing orders, the fluid replacement circuit comprises a replacing fluid container 10 and a second liquid feed means connected to each other by a conduit, the blood circulation circuit and the fluid replacement circuit are coupled with each other at a branch point provided at a desired position between the patient artery connection part 1 and the first liquid feed means, and replacing fluid flow quantity supplied from the fluid replacement circuit to the blood circulation circuit is changed based on a flow ratio between the first liquid feed means and the second liquid feed means.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a blood processing apparatus for performing extracorporeal blood circulation such as artificial dialysis, and more particularly to a simple rehydration apparatus for automatically rehydrating during extracorporeal blood circulation.

[0002]

2. Description of the Related Art Hemodialysis, which purifies a patient's blood through a semipermeable membrane, is generally performed on patients whose function of removing waste products or excess water in body fluids is impaired due to renal failure or the like. Have been done. In this device, it is necessary to efficiently remove waste and excess water in the body while properly maintaining the amount of blood circulating in the patient. Abrupt or excessive water removal can reduce the amount of blood circulating in the body of the patient below an appropriate level, and may cause a decrease in blood pressure, shock, imbalance syndrome and the like. In such cases, hemodialysis may be interrupted depending on the condition, and the patient may be given one
Measures are taken to replace the saline with a volume of 00-300 ml. Various devices have conventionally been devised in preparation for the above cases. For example, JP-B-64-5909 and JP-A-63-63470 each disclose a dialysis mode (a step of performing hemodialysis while performing extracorporeal blood circulation) and a fluid replacement mode (interruption of extracorporeal blood circulation). And a mode in which only fluid replacement is performed). The former is a device that measures the amount of fluid replenished to the patient by the control arithmetic circuit in the fluid replacement mode, and when the amount reaches a preset amount, instructs the switch to switch to return to the dialysis mode. The latter is a device that measures the weight of the replacement fluid in the replacement fluid container before and after the start of replacement fluid, and returns from the replacement fluid mode to the dialysis mode when the replacement fluid weight difference exceeds a preset amount. Each of the above devices requires a switch and a control device for operating the switch, and requires an arithmetic circuit and a means for measuring the replacement fluid for control. In addition, in these devices, the flow path of the extracorporeal blood circulation circuit is forcibly switched by the switch, so that only replacement fluid is performed in the replacement fluid mode, only hemodialysis is performed in the dialysis mode, and replacement fluid is performed while performing hemodialysis. I couldn't do that.

[0003]

SUMMARY OF THE INVENTION An object of the present invention is to solve the problems of the conventional rehydration device as described above. That is, the conventional device firstly required a switch, a control device, and other equipment, and the structure and mechanism were complicated. Second, in the replacement fluid mode or the dialysis mode, only the function in that mode could be performed. For example, it was not possible to perform hemodiafiltration (HDF) in which hemodialysis was performed while performing fluid replacement. Furthermore, it was not possible to precisely control the replacement fluid flow and the blood flow flowing through the extracorporeal circuit by a simple method and means.

[0004]

According to the present invention, there is provided a blood circulation circuit for taking out the patient's blood outside the body and circulating the blood, and a fluid replacement circuit connected to the blood circulation circuit for performing fluid replacement. The patient's arterial connection, arterial-side upstream, first fluid feeding means, arterial-side downstream, blood processor, vein, and patient vein connection are connected in the order of blood flow, and the fluid replacement circuit is an infusion container And the second liquid feeding means are connected by a conduit, and the blood circulation circuit and the rehydration circuit are connected at a branch point provided at an arbitrary position between the patient arterial connection part and the first liquid feeding means. The above problem has been solved by a simple rehydration device characterized in that the flow rate of the replacement fluid flowing from the replacement fluid circuit to the blood circulation circuit changes depending on the flow rate ratio between the first solution sending means and the second solution sending means.

[0005]

FIG. 1 shows an embodiment of the present invention in order to explain the present invention more specifically. FIG. 1 is an improvement of a general hemodialysis apparatus, which is characterized by a replenisher, which is a connection part of a rehydration circuit to a blood circulation circuit (hereinafter also referred to as a blood circuit) and a second fluid supply means provided in the rehydration circuit. A blood pump 5 which is a first liquid supply means provided in the blood circulation circuit downstream of the rehydration pump 11 and the rehydration circuit
By adjusting the amount of fluid supplied, the amount of replacement fluid flowing through the blood circulation circuit can be easily controlled.
That is, the flow path switching device and the flow rate integrating device for controlling the switching device are unnecessary in the device of the present invention. Furthermore, hemofiltration and dialysis, which performs blood circulation simultaneously with replacement fluid, which has been difficult in the past, can be realized with a simple device. Here, for convenience, the blood dialyzer 7 of the blood circuit is used as a boundary, and the upstream side is called an arterial blood circuit, and the downstream side is called a venous blood circuit. The arterial blood circuit includes, in the order of flow, the arterial connection part 1 of the patient, the blood removal part 3 of the circuit upstream of the branch part 2 of the fluid replacement circuit and the blood circulation circuit, the mixing part 4 of the circuit downstream of the branch part, and the mixing. It comprises a blood pump 5 and an artery chamber 6 provided in the section.
The venous blood circuit also includes a venous chamber 8, a patient vein-side connecting portion 9, and the like in the order of flow. The patient's arterial and venous connections 1, 9 are connected to the patient's blood vessels by a puncture needle for hemodialysis. The rehydration circuit is composed of the rehydration container 10 and
Are connected by a conduit, and a rehydration pump 11 is provided in the middle of the conduit. The amount of liquid sent in the mixing unit 4 is
Since the amount of fluid supplied from the blood removal unit 3 and the amount of fluid supplied from the rehydration circuit are added, the ratio of the flow rate of the rehydration pump 11 to the flow rate of the blood pump 5 is changed to allow the blood removal unit 3 The flowing blood flow can be changed. That is, by adjusting the flow ratio between the replacement fluid pump 11 and the blood pump 5, the replacement fluid flow rate flowing from the replacement fluid circuit to the blood circulation circuit can be changed.

The means for measuring the flow ratio of the blood pump and the replacement fluid pump is not particularly limited. Simply, it can be obtained by taking the ratio of the actual measurement value of each flow rate measured by the pump itself. Here, it is desirable to provide interlocking means between the pumps so that the rehydration pump and the blood pump can interlock. Further, it is convenient that this interlocking means is provided with control means for controlling the flow rate of the replacement fluid pump so as not to exceed the flow rate of the blood pump.

[0007]

For example, as shown in Table 1 below, the flow rate of the blood pump 5 was set to 200 while the replacement fluid pump 11 was stopped.
When the flow rate is set to ml / min, the liquid flowing from the mixing section 4 is occupied by the blood from the blood removal section 3 because there is no liquid supply from the rehydration circuit. This is a dialysis mode without replacement fluid. If the flow rate of the rehydration pump 11 is set to 200 ml / min while the flow rate of the blood pump 5 is set to 200 ml / min, on the contrary, all the liquid flowing through the mixing section 4 is occupied by the liquid from the rehydration circuit, and Blood will not flow to the mixing section 4. This is a rehydration mode in which blood circulation is not performed. Further, as shown in Table 1, the flow rate of the replacement fluid pump was set to 0 ml / m
from the flow rate of the blood pump (200 ml /
By changing the flow rate within the range up to min), hemofiltration dialysis in which dialysis is performed while supplementing an arbitrary amount of fluid to the blood circulation circuit becomes possible. However, at this time, if the flow rate of the rehydration pump exceeds the flow rate of the blood pump, the fluid from the rehydration circuit flows backward from the blood removal part to the patient's artery, and the internal pressure of the blood circuit increases, which is not preferable. For this reason, as shown in FIG. 2, interlocking means 12 is provided between both pumps, and control means 13 for controlling the flow rate of rehydration pump 11 so as not to exceed the flow rate of blood pump 5 while measuring the flow rates of both pumps. Is desirably provided.

[0008]

[Table 1]

[0009]

The simple fluid replacement device according to the present invention has the following effects. (1) As described above, the simple fluid replacement device of the present invention does not require a switch or a flow integrating device, and therefore has a simple structure.
Failures are also reduced. (2) By changing the flow ratio between the first liquid sending means and the second liquid sending means, it is possible to set both the fluid replacement mode and the dialysis mode. HDF). Furthermore, the flow rate of replacement fluid and the flow rate of blood flowing in the extracorporeal circuit can be finely controlled by a simple method and means.

[Brief description of the drawings]

FIG. 1 is a schematic view showing one embodiment of a simple fluid replacement device of the present invention.

FIG. 2 is a schematic view showing another embodiment of the simple rehydration device.

[Explanation of symbols]

 1. 1. Patient artery connection Branch part 3. Blood removal unit 4. Mixing section 5. Blood pump 6. 6. Arterial chamber Hemodialysis machine 8. Venous chamber 9. 9. Patient vein connection Refill container 11. Refill pump 12. Interlocking means 13. Control means

Claims (5)

[Claims] 1. A blood circulation circuit for taking out a patient's blood out of the body and circulating the blood, and a rehydration circuit connected to the circulation circuit for rehydrating the blood. The arterial connection section, blood removal section, first liquid supply means, mixing section, blood processor, vein section, and patient vein connection section are provided. The fluid replacement circuit connects the infusion container and the second liquid supply means by a conduit. The blood circulation circuit and the fluid replacement circuit are connected at a branch point provided at an arbitrary position between the patient artery connection part and the first fluid delivery means, and the first fluid delivery means and the second fluid delivery means are connected. A simple fluid replacement device characterized in that the fluid replacement flow rate flowing from the replacement fluid circuit to the blood circulation circuit changes depending on the flow rate ratio of the means. 2. The simple fluid replacement device according to claim 1, wherein the flow rate ratio between the first liquid sending means and the second liquid sending means is obtained by a flow rate ratio of a measured value of each liquid sending means. 3. The simple refilling device according to claim 2, wherein the flow rate of the second liquid sending means does not exceed the flow rate of the first liquid sending means. 4. An interlocking means for interlocking each liquid feeding means between the first liquid feeding means and the second liquid feeding means.
Or the simple rehydration device described in any one of the above items 3. 5. The interlocking means is provided with control means for controlling the flow rate of one of the liquid feeding means and the flow rate of the other of the liquid feeding means.
A simple fluid replacement device according to any one of the above items.