[go: up one dir, main page]

JPH10512453A - ヒト インターロイキン−１ レセプター アクセサリータンパク質 - Google Patents

ヒト インターロイキン−１ レセプター アクセサリータンパク質

Info

Publication number
JPH10512453A
JPH10512453A JP8522598A JP52259896A JPH10512453A JP H10512453 A JPH10512453 A JP H10512453A JP 8522598 A JP8522598 A JP 8522598A JP 52259896 A JP52259896 A JP 52259896A JP H10512453 A JPH10512453 A JP H10512453A
Authority
JP
Japan
Prior art keywords
acp
cells
protein
human
receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP8522598A
Other languages
English (en)
Japanese (ja)
Inventor
アンソニー チゾニテ，リチャード
ウォン ユー，グレイス
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of JPH10512453A publication Critical patent/JPH10512453A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Emergency Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP8522598A 1995-01-23 1996-01-17 ヒト インターロイキン−１ レセプター アクセサリータンパク質 Pending JPH10512453A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37626895A 1995-01-23 1995-01-23
US08/376,268 1995-01-23
PCT/EP1996/000181 WO1996023067A1 (en) 1995-01-23 1996-01-17 Human interleukin-1 receptor accessory protein

Publications (1)

Publication Number Publication Date
JPH10512453A true JPH10512453A (ja) 1998-12-02

Family

ID=23484321

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8522598A Pending JPH10512453A (ja) 1995-01-23 1996-01-17 ヒト インターロイキン−１ レセプター アクセサリータンパク質

Country Status (19)

Country Link
EP (1) EP0808365A1 (es)
JP (1) JPH10512453A (es)
AR (1) AR003919A1 (es)
AU (1) AU4537096A (es)
BR (1) BR9606837A (es)
CA (1) CA2210724A1 (es)
CO (1) CO4480033A1 (es)
CZ (1) CZ208197A3 (es)
EA (1) EA199700265A1 (es)
FI (1) FI973089L (es)
HU (1) HUP9702458A2 (es)
IL (1) IL116796A0 (es)
MX (1) MX9705501A (es)
NO (1) NO973404L (es)
PE (1) PE64396A1 (es)
PL (1) PL321538A1 (es)
TR (1) TR199700652T1 (es)
WO (1) WO1996023067A1 (es)
ZA (1) ZA96333B (es)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013502403A (ja) * 2009-08-21 2013-01-24 カンタージア アクチエボラーグ 新規な薬剤及びその使用
JP2014511348A (ja) * 2011-01-19 2014-05-15 カンタージア アクチエボラーグ 抗ｉｌ−１ｒａｐ抗体及びヒトを処置するためのそれらの使用

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7011696A (en) * 1996-08-26 1998-03-19 Human Genome Sciences, Inc. Soluble interleukin-1 receptor accessory molecule
US6974682B1 (en) 1996-08-26 2005-12-13 Human Genome Sciences, Inc. Soluble interleukin-1 receptor accessory molecule
EP2002846B1 (en) 1996-12-06 2017-01-25 Amgen Inc. Combination therapy using an IL-1 inhibitor for treating IL-1 mediated diseases
US6294170B1 (en) 1997-08-08 2001-09-25 Amgen Inc. Composition and method for treating inflammatory diseases
WO1998049309A1 (en) 1997-04-30 1998-11-05 F. Hoffmann-La Roche Ag Rat st38.2 chemokine
US6280955B1 (en) * 1997-12-16 2001-08-28 Tularik Inc. Interleukin-1 receptor accessory proteins, nucleic acids and methods
JP2001526892A (ja) 1997-12-23 2001-12-25 イミュネックス・コーポレーション Ｓｉｇｉｒｒｄｎａおよびポリペプチド
US6808902B1 (en) 1999-11-12 2004-10-26 Amgen Inc. Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
WO2002064630A2 (en) * 2000-10-31 2002-08-22 Immunex Corporation Il-1 receptor accessory protein
GB2375604A (en) * 2001-05-18 2002-11-20 Warner Lambert Co Methods for screening using interleukin soluble trimolecular complex
PT2087908T (pt) 2001-06-26 2018-07-16 Amgen Inc Anticorpos contra opgl
KR100453877B1 (ko) 2001-07-26 2004-10-20 메덱스젠 주식회사 연쇄체화에 의한 면역 글로블린 융합 단백질의 제조 방법 및 이 방법에 의해 제조된 ＴＮＦＲ/Ｆｃ 융합 단백질, 상기 단백질을 코딩하는 ＤＮＡ, 상기 ＤＮＡ를 포함하는벡터, 및 상기 벡터에 의한 형질전환체
MXPA04001187A (es) * 2001-08-07 2004-07-08 Immunex Corp Receptores de interleucina-1 en el tratamiento de enfermedades.
EA033750B1 (ru) 2002-09-06 2019-11-21 Amgen Inc Изолированная молекула нуклеиновой кислоты, кодирующая антитело человека к рецептору интерлейкина-1, и ее применение
PT1729810T (pt) 2004-04-02 2018-11-22 Swedish Orphan Biovitrum Ab Publ Métodos de redução da agregação de il-ira
US8618054B2 (en) 2004-05-05 2013-12-31 Valorisation-Rechereche Société en Commandite Interleukin-1 receptor antagonists, compositions, and methods of treatment
WO2005105830A1 (en) * 2004-05-05 2005-11-10 Valorisation-Recherche, Societe En Commandite Interleukin-1 receptor antagonists, compositions, and methods of treatment
EP1885855A4 (en) * 2005-05-05 2009-03-04 Valorisation Hsj Soc En Comman CYTOKIN RECEPTOR MODULATORS AND USES THEREOF
US11111544B2 (en) 2005-07-29 2021-09-07 Natera, Inc. System and method for cleaning noisy genetic data and determining chromosome copy number
PE20070684A1 (es) 2005-11-14 2007-08-06 Amgen Inc MOLECULAS QUIMERICAS DE ANTICUERPO RANKL-PTH/PTHrP
US8709715B2 (en) 2008-03-26 2014-04-29 Cellerant Therapeutics, Inc. Cytokine receptors associated with myelogenous haematological proliferative disorders and uses thereof
EP2196476A1 (en) 2008-12-10 2010-06-16 Novartis Ag Antibody formulation
US12152275B2 (en) 2010-05-18 2024-11-26 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US11939634B2 (en) 2010-05-18 2024-03-26 Natera, Inc. Methods for simultaneous amplification of target loci
US20190010543A1 (en) 2010-05-18 2019-01-10 Natera, Inc. Methods for simultaneous amplification of target loci
US12221653B2 (en) 2010-05-18 2025-02-11 Natera, Inc. Methods for simultaneous amplification of target loci
AU2011358564B9 (en) 2011-02-09 2017-07-13 Natera, Inc Methods for non-invasive prenatal ploidy calling
CN103608030A (zh) * 2011-06-21 2014-02-26 昂科发克特公司 用于治疗和诊断癌症的组合物和方法
WO2013006490A2 (en) 2011-07-01 2013-01-10 Cellerant Therapeutics, Inc. Antibodies that specifically bind to tim3
US20140100126A1 (en) 2012-08-17 2014-04-10 Natera, Inc. Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data
GB201403875D0 (en) 2014-03-05 2014-04-16 Cantargia Ab Novel antibodies and uses thereof
US20180173846A1 (en) 2014-06-05 2018-06-21 Natera, Inc. Systems and Methods for Detection of Aneuploidy
GB201413913D0 (en) 2014-08-06 2014-09-17 Cantargia Ab Novel antibodies and uses thereof
EP3294906B1 (en) 2015-05-11 2024-07-10 Natera, Inc. Methods for determining ploidy
CN115505042A (zh) 2015-06-26 2022-12-23 赛诺菲生物技术公司 单克隆抗il-1racp抗体
AU2017249594B2 (en) 2016-04-15 2023-08-24 Natera, Inc. Methods for lung cancer detection
EP3241845A1 (en) 2016-05-06 2017-11-08 MAB Discovery GmbH Humanized anti-il-1r3 antibodies
WO2018022982A1 (en) 2016-07-29 2018-02-01 Trustees Of Boston University Age-associated clonal hematopoiesis accelerates cardio-metabolic disease development
EP3401332A1 (en) 2017-05-08 2018-11-14 MAB Discovery GmbH Anti-il-1r3 antibodies for use in inflammatory conditions
CA3067637A1 (en) 2017-06-20 2018-12-27 The Medical College Of Wisconsin, Inc. Assessing transplant complication risk with total cell-free dna
WO2019118926A1 (en) 2017-12-14 2019-06-20 Tai Diagnostics, Inc. Assessing graft suitability for transplantation
AU2019251504A1 (en) 2018-04-14 2020-08-13 Natera, Inc. Methods for cancer detection and monitoring by means of personalized detection of circulating tumor DNA
US12234509B2 (en) 2018-07-03 2025-02-25 Natera, Inc. Methods for detection of donor-derived cell-free DNA
TW202021618A (zh) 2018-08-17 2020-06-16 美商２３與我有限公司 抗ｉｌ１ｒａｐ抗體及其使用方法
US11931674B2 (en) 2019-04-04 2024-03-19 Natera, Inc. Materials and methods for processing blood samples
WO2021236962A1 (en) 2020-05-20 2021-11-25 The Medical College Of Wisconsin, Inc. Compositions and methods for inhibiting cytokine-release syndrome
US20240224961A1 (en) * 2021-05-28 2024-07-11 Biocytogen Jiangsu Co., Ltd. Genetically modified non-human animal with human or chimeric il1rap
AR130550A1 (es) 2022-09-21 2024-12-18 Sanofi Biotechnology Anticuerpo anti-il-1r3 humanizado y métodos de uso

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013502403A (ja) * 2009-08-21 2013-01-24 カンタージア アクチエボラーグ 新規な薬剤及びその使用
JP2014511348A (ja) * 2011-01-19 2014-05-15 カンタージア アクチエボラーグ 抗ｉｌ−１ｒａｐ抗体及びヒトを処置するためのそれらの使用

Also Published As

Publication number Publication date
BR9606837A (pt) 1998-05-26
EA199700265A1 (ru) 1998-04-30
PL321538A1 (en) 1997-12-08
CZ208197A3 (en) 1997-11-12
ZA96333B (en) 1996-07-23
IL116796A0 (en) 1996-05-14
NO973404D0 (no) 1997-07-23
CO4480033A1 (es) 1997-07-09
WO1996023067A1 (en) 1996-08-01
CA2210724A1 (en) 1996-08-01
EP0808365A1 (en) 1997-11-26
FI973089A0 (fi) 1997-07-22
AU4537096A (en) 1996-08-14
NO973404L (no) 1997-07-23
FI973089L (fi) 1997-07-22
PE64396A1 (es) 1997-01-28
TR199700652T1 (xx) 1998-02-21
AR003919A1 (es) 1998-09-30
HUP9702458A2 (hu) 1998-04-28
MX9705501A (es) 1997-10-31

Similar Documents

Publication Publication Date Title
JPH10512453A (ja) ヒト インターロイキン−１ レセプター アクセサリータンパク質
US6372899B1 (en) Purified genes encoding mammalian cell surface antigens; proteins and antibodies
JP3520272B2 (ja) リンパ球機能関連抗原３のｃｄ２結合ドメイン
WO1998055621A1 (en) Ntn-2 member of tnf ligand family
WO1998055620A1 (en) Ntn-2 member of tnf ligand family
JP2001157593A (ja) 哺乳動物ケモカインｃｃｆ１８およびレセプターｃｃｋｒ３
WO1994017184A1 (en) Modulation of physiological responses of lymphocytes by cd38 or antibodies thereto
WO1996029348A1 (en) Monoclonal antibody against human receptor protein 4-1bb and methods of its use for treatment of diseases
JP2001512017A (ja) 哺乳動物細胞膜タンパク質；関連試薬
CA2299619A1 (en) Human orphan receptor ntr-1
JP2001507219A (ja) 単離された哺乳動物単球細胞遺伝子；関連する試薬
JP2001501813A (ja) 分泌蛋白およびそれらをコードするポリヌクレオチド
JP2003523735A (ja) ヒトナチュラルキラー細胞によって媒介される天然細胞毒性に関連した新規トリガリングレセプターおよび同一の性質を有する抗体
JPH08510907A (ja) リンパ球化学誘引因子およびその用途
KR100676229B1 (ko) 신경영양성 인자 수용체
JPH09511387A (ja) 新規な細胞表面受容体、抗体組成物、及びこれらの使用方法
US5728548A (en) Retinoid receptor-1 (RR1) and DNA encoding RR1
WO1998009638A1 (en) INHIBITION OF MAST CELL ACTIVATION BY gp49-BASED MECHANISMS AND REAGENTS
KR20010043088A (ko) 신규인 폴리펩티드, 그 폴리펩티드를 코드화하는 ｃＤＮＡ및 그 용도
JP2000515726A (ja) 分泌蛋白をコードする成人ｐｂｍｃ由来のポリヌクレオチド
EP0795014B1 (en) Costimulatory T cell surface antigen SLAM
EP1027436A1 (en) Viral encoded semaphorin protein receptor dna and polypeptides
WO2000032633A1 (en) Novel adhesion molecule and methods of use
WO1995002611A1 (en) Cell surface protein present on nk (natural killer cells) named dx1
JP2000508908A (ja) 分泌蛋白およびそれらをコードしているポリヌクレオチド