JPH09255560A - Gel-like emulsified composition - Google Patents
Gel-like emulsified compositionInfo
- Publication number
- JPH09255560A JPH09255560A JP6656396A JP6656396A JPH09255560A JP H09255560 A JPH09255560 A JP H09255560A JP 6656396 A JP6656396 A JP 6656396A JP 6656396 A JP6656396 A JP 6656396A JP H09255560 A JPH09255560 A JP H09255560A
- Authority
- JP
- Japan
- Prior art keywords
- powder
- water
- polysaccharide
- present
- emulsified composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 107
- 239000000843 powder Substances 0.000 claims abstract description 85
- 150000004676 glycans Chemical class 0.000 claims abstract description 53
- 229920001282 polysaccharide Polymers 0.000 claims abstract description 53
- 239000005017 polysaccharide Substances 0.000 claims abstract description 53
- 239000002537 cosmetic Substances 0.000 claims abstract description 51
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 claims abstract description 30
- 239000003814 drug Substances 0.000 claims abstract description 22
- 241000589516 Pseudomonas Species 0.000 claims abstract description 16
- 229940079593 drug Drugs 0.000 claims abstract description 15
- SHZGCJCMOBCMKK-UHFFFAOYSA-N D-mannomethylose Natural products CC1OC(O)C(O)C(O)C1O SHZGCJCMOBCMKK-UHFFFAOYSA-N 0.000 claims abstract description 11
- SHZGCJCMOBCMKK-JFNONXLTSA-N L-rhamnopyranose Chemical compound C[C@@H]1OC(O)[C@H](O)[C@H](O)[C@H]1O SHZGCJCMOBCMKK-JFNONXLTSA-N 0.000 claims abstract description 11
- PNNNRSAQSRJVSB-UHFFFAOYSA-N L-rhamnose Natural products CC(O)C(O)C(O)C(O)C=O PNNNRSAQSRJVSB-UHFFFAOYSA-N 0.000 claims abstract description 11
- IAJILQKETJEXLJ-UHFFFAOYSA-N Galacturonsaeure Natural products O=CC(O)C(O)C(O)C(O)C(O)=O IAJILQKETJEXLJ-UHFFFAOYSA-N 0.000 claims abstract description 9
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims abstract description 9
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims abstract description 9
- 239000008103 glucose Substances 0.000 claims abstract description 9
- 229940097043 glucuronic acid Drugs 0.000 claims abstract description 9
- 239000000470 constituent Substances 0.000 claims abstract description 8
- 239000004205 dimethyl polysiloxane Substances 0.000 claims abstract description 8
- 235000013870 dimethyl polysiloxane Nutrition 0.000 claims abstract description 8
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims abstract description 8
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims abstract description 6
- 238000009835 boiling Methods 0.000 claims abstract description 4
- AEMOLEFTQBMNLQ-AQKNRBDQSA-N D-glucopyranuronic acid Chemical compound OC1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O AEMOLEFTQBMNLQ-AQKNRBDQSA-N 0.000 claims abstract 2
- 239000000839 emulsion Substances 0.000 claims description 48
- 239000003795 chemical substances by application Substances 0.000 claims description 42
- 239000000341 volatile oil Substances 0.000 claims description 35
- 229920003176 water-insoluble polymer Polymers 0.000 claims description 30
- 150000002148 esters Chemical class 0.000 claims description 7
- 229930195733 hydrocarbon Natural products 0.000 claims description 7
- 150000002430 hydrocarbons Chemical class 0.000 claims description 7
- 235000000346 sugar Nutrition 0.000 claims description 7
- 125000004432 carbon atom Chemical group C* 0.000 claims description 6
- 108090000623 proteins and genes Proteins 0.000 claims description 6
- 102000004169 proteins and genes Human genes 0.000 claims description 6
- 229920000178 Acrylic resin Polymers 0.000 claims description 4
- 239000004925 Acrylic resin Substances 0.000 claims description 4
- 239000004215 Carbon black (E152) Substances 0.000 claims description 4
- 239000004952 Polyamide Substances 0.000 claims description 4
- 229920002647 polyamide Polymers 0.000 claims description 4
- 125000004122 cyclic group Chemical group 0.000 claims description 3
- 239000013638 trimer Substances 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 abstract description 42
- 238000002360 preparation method Methods 0.000 abstract description 17
- 239000004615 ingredient Substances 0.000 abstract description 6
- 238000009472 formulation Methods 0.000 abstract description 5
- 244000005700 microbiome Species 0.000 abstract description 4
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 239000000314 lubricant Substances 0.000 abstract 1
- 230000009885 systemic effect Effects 0.000 abstract 1
- 239000006071 cream Substances 0.000 description 76
- 230000000052 comparative effect Effects 0.000 description 33
- 239000003921 oil Substances 0.000 description 16
- 235000019198 oils Nutrition 0.000 description 14
- 239000012071 phase Substances 0.000 description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 12
- 229940121375 antifungal agent Drugs 0.000 description 10
- 238000012360 testing method Methods 0.000 description 10
- 238000011156 evaluation Methods 0.000 description 9
- 230000000843 anti-fungal effect Effects 0.000 description 8
- 230000014759 maintenance of location Effects 0.000 description 8
- 238000002156 mixing Methods 0.000 description 8
- IAJILQKETJEXLJ-QTBDOELSSA-N aldehydo-D-glucuronic acid Chemical compound O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)C(O)=O IAJILQKETJEXLJ-QTBDOELSSA-N 0.000 description 7
- 239000003349 gelling agent Substances 0.000 description 7
- 238000000034 method Methods 0.000 description 7
- 229920000642 polymer Polymers 0.000 description 7
- -1 polysiloxanes Polymers 0.000 description 7
- 239000000047 product Substances 0.000 description 7
- 229920001817 Agar Polymers 0.000 description 6
- 239000008272 agar Substances 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- 229920000620 organic polymer Polymers 0.000 description 6
- 108010010803 Gelatin Proteins 0.000 description 5
- 239000008346 aqueous phase Substances 0.000 description 5
- 238000004140 cleaning Methods 0.000 description 5
- 229920001577 copolymer Polymers 0.000 description 5
- 239000008273 gelatin Substances 0.000 description 5
- 229920000159 gelatin Polymers 0.000 description 5
- 235000019322 gelatine Nutrition 0.000 description 5
- 235000011852 gelatine desserts Nutrition 0.000 description 5
- 229940057995 liquid paraffin Drugs 0.000 description 5
- 238000004519 manufacturing process Methods 0.000 description 5
- 238000003756 stirring Methods 0.000 description 5
- 239000002562 thickening agent Substances 0.000 description 5
- 239000004677 Nylon Substances 0.000 description 4
- 150000001298 alcohols Chemical class 0.000 description 4
- 239000002260 anti-inflammatory agent Substances 0.000 description 4
- 239000003599 detergent Substances 0.000 description 4
- 238000004945 emulsification Methods 0.000 description 4
- 239000003995 emulsifying agent Substances 0.000 description 4
- 238000000855 fermentation Methods 0.000 description 4
- 230000004151 fermentation Effects 0.000 description 4
- 230000002045 lasting effect Effects 0.000 description 4
- 229920001778 nylon Polymers 0.000 description 4
- 230000000149 penetrating effect Effects 0.000 description 4
- 229920001296 polysiloxane Polymers 0.000 description 4
- SGVYKUFIHHTIFL-UHFFFAOYSA-N 2-methylnonane Chemical compound CCCCCCCC(C)C SGVYKUFIHHTIFL-UHFFFAOYSA-N 0.000 description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 3
- 241001082081 Elodia Species 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 229940121363 anti-inflammatory agent Drugs 0.000 description 3
- 229910052799 carbon Inorganic materials 0.000 description 3
- 238000013329 compounding Methods 0.000 description 3
- 230000006866 deterioration Effects 0.000 description 3
- 235000014113 dietary fatty acids Nutrition 0.000 description 3
- 239000000194 fatty acid Substances 0.000 description 3
- 229930195729 fatty acid Natural products 0.000 description 3
- 150000004665 fatty acids Chemical class 0.000 description 3
- 230000007794 irritation Effects 0.000 description 3
- 229920000058 polyacrylate Polymers 0.000 description 3
- 150000008163 sugars Chemical class 0.000 description 3
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 2
- OCAPBUJLXMYKEJ-UHFFFAOYSA-N 1-[biphenyl-4-yl(phenyl)methyl]imidazole Chemical compound C1=NC=CN1C(C=1C=CC(=CC=1)C=1C=CC=CC=1)C1=CC=CC=C1 OCAPBUJLXMYKEJ-UHFFFAOYSA-N 0.000 description 2
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 description 2
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 2
- CNPVJWYWYZMPDS-UHFFFAOYSA-N 2-methyldecane Chemical compound CCCCCCCCC(C)C CNPVJWYWYZMPDS-UHFFFAOYSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 description 2
- BAPJBEWLBFYGME-UHFFFAOYSA-N Methyl acrylate Chemical compound COC(=O)C=C BAPJBEWLBFYGME-UHFFFAOYSA-N 0.000 description 2
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 description 2
- 229920002472 Starch Polymers 0.000 description 2
- 239000006096 absorbing agent Substances 0.000 description 2
- 239000003242 anti bacterial agent Substances 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 239000003429 antifungal agent Substances 0.000 description 2
- 239000000739 antihistaminic agent Substances 0.000 description 2
- 239000003963 antioxidant agent Substances 0.000 description 2
- 229960002206 bifonazole Drugs 0.000 description 2
- 239000002738 chelating agent Substances 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 230000002542 deteriorative effect Effects 0.000 description 2
- 239000002552 dosage form Substances 0.000 description 2
- 239000000499 gel Substances 0.000 description 2
- ZUBZATZOEPUUQF-UHFFFAOYSA-N isononane Chemical compound CCCCCCC(C)C ZUBZATZOEPUUQF-UHFFFAOYSA-N 0.000 description 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 2
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 description 2
- 230000035515 penetration Effects 0.000 description 2
- 239000003755 preservative agent Substances 0.000 description 2
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 description 2
- 239000008107 starch Substances 0.000 description 2
- 235000019698 starch Nutrition 0.000 description 2
- 239000003270 steroid hormone Substances 0.000 description 2
- 150000005846 sugar alcohols Polymers 0.000 description 2
- 150000003626 triacylglycerols Chemical class 0.000 description 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 1
- ALSTYHKOOCGGFT-KTKRTIGZSA-N (9Z)-octadecen-1-ol Chemical compound CCCCCCCC\C=C/CCCCCCCCO ALSTYHKOOCGGFT-KTKRTIGZSA-N 0.000 description 1
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 1
- FFJCNSLCJOQHKM-CLFAGFIQSA-N (z)-1-[(z)-octadec-9-enoxy]octadec-9-ene Chemical compound CCCCCCCC\C=C/CCCCCCCCOCCCCCCCC\C=C/CCCCCCCC FFJCNSLCJOQHKM-CLFAGFIQSA-N 0.000 description 1
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 description 1
- AXTGDCSMTYGJND-UHFFFAOYSA-N 1-dodecylazepan-2-one Chemical compound CCCCCCCCCCCCN1CCCCCC1=O AXTGDCSMTYGJND-UHFFFAOYSA-N 0.000 description 1
- LEEDMQGKBNGPDN-UHFFFAOYSA-N 2-methylnonadecane Chemical compound CCCCCCCCCCCCCCCCCC(C)C LEEDMQGKBNGPDN-UHFFFAOYSA-N 0.000 description 1
- GTJOHISYCKPIMT-UHFFFAOYSA-N 2-methylundecane Chemical compound CCCCCCCCCC(C)C GTJOHISYCKPIMT-UHFFFAOYSA-N 0.000 description 1
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- ALYNCZNDIQEVRV-UHFFFAOYSA-N 4-aminobenzoic acid Chemical class NC1=CC=C(C(O)=O)C=C1 ALYNCZNDIQEVRV-UHFFFAOYSA-N 0.000 description 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N 4-hydroxybenzoic acid Chemical compound OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 1
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- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 description 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 1
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- VIZORQUEIQEFRT-UHFFFAOYSA-N Diethyl adipate Chemical compound CCOC(=O)CCCCC(=O)OCC VIZORQUEIQEFRT-UHFFFAOYSA-N 0.000 description 1
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- BIVBRWYINDPWKA-VLQRKCJKSA-L Glycyrrhizinate dipotassium Chemical compound [K+].[K+].O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@H]1CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@](C)(CC[C@@]5(CC[C@@]4(C)[C@]3(C)CC[C@H]2C1(C)C)C)C(O)=O)C([O-])=O)[C@@H]1O[C@H](C([O-])=O)[C@@H](O)[C@H](O)[C@H]1O BIVBRWYINDPWKA-VLQRKCJKSA-L 0.000 description 1
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- 235000019808 microcrystalline wax Nutrition 0.000 description 1
- 230000001333 moisturizer Effects 0.000 description 1
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 description 1
- GOQYKNQRPGWPLP-UHFFFAOYSA-N n-heptadecyl alcohol Natural products CCCCCCCCCCCCCCCCCO GOQYKNQRPGWPLP-UHFFFAOYSA-N 0.000 description 1
- 239000002736 nonionic surfactant Substances 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- WWZKQHOCKIZLMA-UHFFFAOYSA-M octanoate Chemical compound CCCCCCCC([O-])=O WWZKQHOCKIZLMA-UHFFFAOYSA-M 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 229940055577 oleyl alcohol Drugs 0.000 description 1
- XMLQWXUVTXCDDL-UHFFFAOYSA-N oleyl alcohol Natural products CCCCCCC=CCCCCCCCCCCO XMLQWXUVTXCDDL-UHFFFAOYSA-N 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- PNJWIWWMYCMZRO-UHFFFAOYSA-N pent‐4‐en‐2‐one Natural products CC(=O)CC=C PNJWIWWMYCMZRO-UHFFFAOYSA-N 0.000 description 1
- 229940066842 petrolatum Drugs 0.000 description 1
- 235000019271 petrolatum Nutrition 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 230000003169 placental effect Effects 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 230000001953 sensory effect Effects 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- 229940032094 squalane Drugs 0.000 description 1
- 238000010186 staining Methods 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 229940012831 stearyl alcohol Drugs 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- 239000011550 stock solution Substances 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 239000003760 tallow Substances 0.000 description 1
- BWMISRWJRUSYEX-SZKNIZGXSA-N terbinafine hydrochloride Chemical compound Cl.C1=CC=C2C(CN(C\C=C\C#CC(C)(C)C)C)=CC=CC2=C1 BWMISRWJRUSYEX-SZKNIZGXSA-N 0.000 description 1
- 201000004647 tinea pedis Diseases 0.000 description 1
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 description 1
- 229960001295 tocopherol Drugs 0.000 description 1
- 229930003799 tocopherol Natural products 0.000 description 1
- 235000010384 tocopherol Nutrition 0.000 description 1
- 239000011732 tocopherol Substances 0.000 description 1
- 239000007762 w/o emulsion Substances 0.000 description 1
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1
Landscapes
- Cosmetics (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
【０００１】[0001]
【発明の属する技術分野】本発明は、乳化組成物に関
し、詳しくは、界面活性剤の配合量が軽減された化粧料
あるいは医薬品に好適な乳化組成物に関する。TECHNICAL FIELD The present invention relates to an emulsified composition, and more particularly to an emulsified composition containing a reduced amount of a surfactant and suitable for cosmetics or pharmaceuticals.
【０００２】[0002]
【従来の技術】化粧料や皮膚外用医薬品において界面活
性剤は、水と油性成分を乳化あるいは可溶化させたり、
粉体成分を基剤に安定に分散させたりするために、ま
た、化粧落とし料においては、汚れを溶解・分散・脱離
させるために配合される必要不可欠な成分であった。し
かしながら、その一方で界面活性剤は、上記化粧料や皮
膚外用医薬品に配合する際に安全性上好ましい成分とは
言えなかった。これは、界面活性剤の有する界面活性作
用が上記の様に有用に作用すると同時に皮膚に対しては
刺激を発現させ易いためである。また、界面活性剤は、
親油性と親水性の両方の性質を兼ね備えているために、
メークアップ化粧料の化粧持ちにもあまり良い影響を与
えないと言われている。さらに、クレンジング料の様な
化粧落とし料では、拭き取りきれずに皮膚上に残存する
界面活性剤による刺激と拭き取りの際の摩擦による刺激
の相乗作用から発赤等を起こすこともあった。BACKGROUND OF THE INVENTION In cosmetics and external medicines for skin, surfactants are used to emulsify or solubilize water and oily ingredients,
It was an indispensable component that was blended in order to stably disperse the powder component in the base material and in the makeup remover to dissolve, disperse, and remove stains. On the other hand, however, the surfactant cannot be said to be a preferable component in terms of safety when incorporated into the above cosmetics or skin external medicine. This is because the surface-active effect of the surface-active agent acts usefully as described above, and at the same time, irritation is easily exerted on the skin. In addition, the surfactant is
Because it has both lipophilic and hydrophilic properties,
It is said that it does not affect the makeup retention of makeup cosmetics very well. Further, makeup removers such as cleansing agents sometimes cause redness due to a synergistic effect of irritation caused by a surfactant remaining on the skin without being wiped off and irritation caused by friction during wiping.
【０００３】この様な状況を反映して、これまでに化粧
料や皮膚外用医薬品に配合する界面活性剤量の減量を目
的として様々な方法が試みられてきた。前記方法の例と
して、ベントナイト−水のゲル中に油性成分を均一分散
した剤形や糖−ポリグリセリンエステル−炭化水素から
なる油性ゲル中に多量の水相を内包させた高内相Ｗ／Ｏ
エマルジョン、長鎖アルキルアクリル酸エステルポリマ
ー等の自己乳化型増粘剤による乳化等が挙げられる。Reflecting such a situation, various methods have been attempted so far for the purpose of reducing the amount of the surfactant compounded in the cosmetics and the skin external medicine. As an example of the method, a high internal phase W / O in which a large amount of an aqueous phase is encapsulated in an oily gel composed of bentonite-water gel in which an oily component is uniformly dispersed or sugar-polyglycerin ester-hydrocarbon
Examples thereof include emulsification with a self-emulsifying thickener such as an emulsion and a long-chain alkyl acrylate polymer.
【０００４】これらの方法によって、界面活性剤によら
ない乳化や配合界面活性剤量を著しく減少させた乳化が
可能となったが、ベントナイト系についてはゲル化が止
まらず数年で乳化物が固化してしまうという問題があ
り、高内相Ｗ／Ｏエマルジョンについては処方成分の自
由度が少ないという問題があり、また、自己乳化型増粘
剤による乳化は増粘剤の影響で粉体が凝集し易くなるこ
とからファンデーション系では使いにくいという問題が
あった。These methods have made it possible to emulsify without using a surfactant or to significantly reduce the amount of the compounded surfactant, but for the bentonite type, gelation does not stop and the emulsion solidifies within a few years. There is a problem that the degree of freedom of prescription components is low for high internal phase W / O emulsions. Also, emulsification with self-emulsifying thickeners causes the powder to aggregate due to the effect of the thickeners. There is a problem that it is difficult to use in a foundation system because it is easy to do.
【０００５】また、有機高分子ゲル化剤を用いた乳化で
は、寒天やゼラチンを用いてこの中に油性成分を分散し
て乳化する技術が知られていたが、寒天やゼラチンを用
いた乳化物では、潤いのあるしっとりとしたあるいはさ
っぱりとした好ましい使用感が得られるものの、界面活
性剤が少ない分、洗浄機能や浸透作用等の機能が損なわ
れるという問題があった。さらに、寒天やゼラチンを用
いた乳化物では、手に取ったときにボロボロ感があり使
用性に問題があった。そこで、化粧料や皮膚外用医薬品
等に利用される乳化組成物において、乳化剤形を維持し
つつ、使用性や乳化組成物が本来的に有する洗浄作用、
浸透作用等の機能を損なうことなく、界面活性剤の配合
量を減量する方法が求められていた。Further, in the emulsification using an organic polymer gelling agent, a technique has been known in which an agar component or gelatin is used to disperse an oily component therein to emulsify. However, an emulsion using agar or gelatin is known. However, although a moist, moist or refreshing feeling of use can be obtained, there is a problem that functions such as a cleaning function and a penetrating action are impaired due to the small amount of the surfactant. Further, an emulsion using agar or gelatin has a tattered feeling when picked up and has a problem in usability. Therefore, in the emulsified composition used for cosmetics and skin external medicine, while maintaining the emulsifier form, the usability and the cleaning action originally possessed by the emulsified composition,
There has been a demand for a method of reducing the compounding amount of the surfactant without impairing functions such as penetrating action.
【０００６】一方、シュードモナス・エロディア等の微
生物が産生しうる後述の一般式（Ｉ）で表される様なグ
ルコース、グルクロン酸及びラムノースを構成糖とする
多糖類については、ゲル化剤として食品等に用いられる
ことは知られていたが、乳化組成物に使用して使用性や
乳化性に問題のない乳化組成物が得られたという報告は
ない。On the other hand, with regard to polysaccharides composed of glucose, glucuronic acid and rhamnose represented by the following general formula (I) which can be produced by microorganisms such as Pseudomonas erodia, foods etc. can be used as gelling agents. However, there is no report that an emulsified composition having no problem in usability and emulsifying property was obtained by using it in an emulsified composition.
【０００７】[0007]
【発明が解決しようとする課題】本発明は上記観点から
なされたものであり、使用感に優れ、使用性や乳化組成
物が本来的に有する機能を損なわずに界面活性剤の配合
量が減量された化粧料、皮膚外用医薬品等の乳化組成物
を提供することを課題とする。SUMMARY OF THE INVENTION The present invention has been made from the above point of view, is excellent in usability, and can reduce the amount of the surfactant blended without impairing the usability and the inherent function of the emulsion composition. It is an object of the present invention to provide an emulsified composition such as a cosmetic or a skin external drug.
【０００８】[0008]
【課題を解決するための手段】本発明者らは、上記課題
を解決するために鋭意研究を行った結果、乳化組成物に
(1)シュードモナス・エロディアが産生する特定の多糖
類と、(2)揮発性油剤と、(3)カルボニル基を有する水不
溶性高分子粉末と、を配合することで、好ましい使用感
が得られ、且つ乳化剤形を維持しつつも使用性や乳化組
成物が本来的に有する洗浄作用、浸透作用等の機能を損
なうことなく、界面活性剤の配合量を減量できることを
見出し、本発明を完成させた。Means for Solving the Problems As a result of intensive studies to solve the above problems, the present inventors have found that an emulsion composition is obtained.
(1) A specific polysaccharide produced by Pseudomonas erodia, (2) a volatile oil, and (3) a water-insoluble polymer powder having a carbonyl group, by blending, a preferred feeling of use is obtained, And, while maintaining the emulsifier form, it was found that the compounding amount of the surfactant can be reduced without impairing the functions such as the cleaning action and the penetrating action originally possessed by the emulsified composition, and the present invention was completed. .
【０００９】すなわち本発明は、(1)シュードモナス・
エロディアが産生するグルコース、グルクロン酸及びラ
ムノースを構成糖とする多糖類と、(2)揮発性油剤と、
(3)カルボニル基を有する水不溶性高分子粉末と、を含
有する乳化組成物である。That is, the present invention provides (1) Pseudomonas
Glucose produced by Elodia, a polysaccharide having glucuronic acid and rhamnose as constituent sugars, and (2) a volatile oil agent,
(3) A water-insoluble polymer powder having a carbonyl group, which is an emulsion composition.
【００１０】ここで、本発明に用いるシュードモナス・
エロディアが産生する前記多糖類とは、シュードモナス
・エロディアにより産生されうる多糖類を意味する。つ
まり、本発明に用いる前記多糖類は、シュードモナス・
エロディアが産生した多糖類に限定されるものではな
く、シュードモナス・エロディア以外の微生物によって
生産された前記多糖類と同様の多糖類も本発明に用いる
ことが可能である。Here, Pseudomonas used in the present invention
The polysaccharide produced by Elodia means a polysaccharide that can be produced by Pseudomonas erodia. That is, the polysaccharide used in the present invention is Pseudomonas
It is not limited to the polysaccharide produced by Elodia, and the same polysaccharides as the above-mentioned polysaccharide produced by microorganisms other than Pseudomonas erodia can also be used in the present invention.
【００１１】本発明の乳化組成物が含有する上記多糖類
として、具体的には、下記一般式（Ｉ）に示される［→
３）−β−D−グルコース（１→４）−β−D−グルクロ
ン酸（１→４）−β−D−グルコース（１→４）−α−L
−ラムノース（１→］を繰り返し単位とする多糖類を挙
げることができる。The polysaccharide contained in the emulsion composition of the present invention is specifically represented by the following general formula (I) [→
3) -β-D-glucose (1 → 4) -β-D-glucuronic acid (1 → 4) -β-D-glucose (1 → 4) -α-L
There may be mentioned polysaccharides having rhamnose (1 →) as a repeating unit.
【００１２】[0012]
【化２】 Embedded image
【００１３】（但し、ｎは整数を表す。） 本発明に用いる上記一般式（Ｉ）で示される多糖類にお
いて、式中のｎは整数を表すが、本発明において好まし
い多糖類のｎの数は、２〜４０００であり、１０〜１０
００であることがより好ましく、さらに好ましくは２０
〜５００である。(However, n represents an integer.) In the polysaccharide represented by the above general formula (I) used in the present invention, n in the formula represents an integer, but the number of n in the polysaccharide which is preferable in the present invention. Is 2 to 4000, and 10 to 10
It is more preferably 00, further preferably 20
~ 500.
【００１４】本発明の乳化組成物に用いる揮発性油剤と
しては、水と任意の割合で混合しない液体すなわち油剤
であって、室温で揮散する性質を有する油剤であれば特
に制限されずに挙げることができる。具体的には、大気
圧下における沸点が２００℃未満である油剤を挙げるこ
とができ、より具体的には、粘度０．１〜１０センチス
トークスのジメチルポリシロキサン、３〜６量体の環状
ジメチルポリシロキサン、炭素数２０未満の分岐の炭化
水素及び総炭素数１２未満のエステル等を挙げることが
できる。さらに、これらの揮発性油剤は１種が単独で又
は２種以上が混合物として本発明の乳化組成物に用いら
れる。The volatile oil agent used in the emulsified composition of the present invention is not particularly limited as long as it is a liquid which is not mixed with water at an arbitrary ratio, that is, an oil agent which has a property of volatilizing at room temperature. You can Specific examples thereof include an oil agent having a boiling point of less than 200 ° C. under atmospheric pressure, and more specifically, a dimethylpolysiloxane having a viscosity of 0.1 to 10 centistokes and a cyclic dimethyl of 3 to 6 mer. Examples thereof include polysiloxanes, branched hydrocarbons having less than 20 carbon atoms and esters having less than 12 total carbon atoms. Furthermore, one kind of these volatile oil agents is used alone or two or more kinds thereof are used as a mixture in the emulsion composition of the present invention.
【００１５】本発明の乳化組成物に用いるカルボニル基
を有する水不溶性高分子粉末としては、分子構造中にカ
ルボニル基を有する高分子化合物であって水に不溶性の
粉末であれば特に制限されないが、具体的には、セルロ
ース粉末、デンプン粉末等の水不溶性多糖類粉末、シル
クパウダー、牛皮革粉末等の水不溶性タンパク質粉末、
ナイロンパウダー等のポリアミド粉末、アクリル酸、メ
タアクリル酸及びこれらのエステルのポリマー粉末やこ
れらの共重合体粉末等のアクリル樹脂粉末等を挙げるこ
とができる。これらのカルボニル基を有する水不溶性高
分子粉末は、１種が単独で又は２種以上が混合物として
本発明の乳化組成物に用いられる。また、これらのうち
でもセルロース粉末、シルクパウダー、牛皮革粉末等が
本発明の乳化組成物において好ましく用いられる。The water-insoluble polymer powder having a carbonyl group used in the emulsion composition of the present invention is not particularly limited as long as it is a polymer compound having a carbonyl group in its molecular structure and is a water-insoluble powder. Specifically, cellulose powder, water-insoluble polysaccharide powder such as starch powder, silk powder, water-insoluble protein powder such as cowhide powder,
Examples thereof include polyamide powder such as nylon powder, polymer powder of acrylic acid, methacrylic acid and their esters, and acrylic resin powder such as copolymer powder of these. These water-insoluble polymer powders having a carbonyl group are used singly or as a mixture of two or more kinds in the emulsion composition of the present invention. Of these, cellulose powder, silk powder, cowhide powder and the like are preferably used in the emulsion composition of the present invention.
【００１６】本発明の乳化組成物における上記多糖類、
揮発性油剤、並びにカルボニル基を有する水不溶性高分
子粉末の含有量であるが、多糖類については組成物全量
に対して０．１〜５重量％であることが好ましく、揮発
性油剤については組成物全量に対して１〜９０重量％で
あることが好ましく、また、カルボニル基を有する水不
溶性高分子粉末については組成物全量に対して０．１〜
２０重量％であることが好ましい。The above-mentioned polysaccharide in the emulsion composition of the present invention,
The content of the volatile oil agent and the water-insoluble polymer powder having a carbonyl group is preferably 0.1 to 5% by weight based on the total amount of the composition for the polysaccharide and the composition for the volatile oil agent. The amount is preferably 1 to 90% by weight based on the total amount of the composition, and the water-insoluble polymer powder having a carbonyl group is 0.1 to 90% by weight based on the total amount of the composition.
Preferably it is 20% by weight.
【００１７】本発明の乳化組成物は、上記多糖類と揮発
性油剤とカルボニル基を有する水不溶性高分子粉末とと
もに、通常の乳化組成物が含有する基剤成分を含有し、
さらに、界面活性剤や各種用途、目的等にあわせて適宜
選択される各種成分を任意に含有する。通常の乳化組成
物において基剤成分は水相成分と油相成分とからなる
が、本発明の乳化組成物においてはこの油相成分を上記
揮発性油剤とそれ以外の油剤で構成することが可能であ
り、また上記揮発性油剤のみで構成することも可能であ
る。この様な本発明の乳化組成物は、上記多糖類を水相
成分に揮発性油剤を油相成分に、また、カルボニル基を
有する水不溶性高分子粉末をそのどちらかに、それぞれ
配合する以外は、通常の乳化組成物と同様にして製造す
ることができる。The emulsified composition of the present invention contains the above-mentioned polysaccharide, volatile oil agent, and water-insoluble polymer powder having a carbonyl group, and a base component contained in a usual emulsified composition,
Further, it optionally contains a surfactant and various components appropriately selected according to various uses and purposes. In the usual emulsified composition, the base component consists of an aqueous phase component and an oil phase component, but in the emulsified composition of the present invention, this oil phase component can be composed of the above volatile oil agent and other oil agents. It is also possible to use only the above volatile oil agent. Such an emulsion composition of the present invention, except that the above-mentioned polysaccharide is added to the water phase component, the volatile oil agent is added to the oil phase component, and the water-insoluble polymer powder having a carbonyl group is added to either of them. It can be produced in the same manner as an ordinary emulsion composition.
【００１８】本発明の乳化組成物として具体的には、化
粧料や皮膚外用医薬品等を挙げることができる。本発明
の乳化組成物は、上記のようにシュードモナス・エロデ
ィアが産生するグルコース、グルクロン酸及びラムノー
スを構成糖とする多糖類と、揮発性油剤と、カルボニル
基を有する水不溶性高分子粉末と、を含有するものであ
って、これらを含有することで、組成物に潤いのあるし
っとりとしたあるいはさっぱりとした好ましい使用感を
付与することができ、さらに、乳化組成物が本来的に有
する洗浄作用や浸透作用等の機能を損なうことなく組成
物中の界面活性剤の含有量を少なくすることができる。
また、従来の有機高分子ゲル化剤を用いた乳化組成物で
問題とされていたボロボロ感を改善して使用性をよくす
ることも可能である。なお、本発明の乳化組成物におい
てはこれら成分を含有することで乳化剤形に支障を与え
ることもない。Specific examples of the emulsified composition of the present invention include cosmetics and skin external medicines. The emulsified composition of the present invention comprises glucose produced by Pseudomonas erodia as described above, a polysaccharide having glucuronic acid and rhamnose as a constituent sugar, a volatile oil agent, and a water-insoluble polymer powder having a carbonyl group. What is contained, by containing these, it is possible to impart a moist or moist or refreshing preferred use feeling to the composition, and further, the cleaning action originally possessed by the emulsion composition or The content of the surfactant in the composition can be reduced without impairing the functions such as the penetration effect.
Further, it is possible to improve the usability by improving the tattered feeling which has been a problem in the conventional emulsified composition using the organic polymer gelling agent. The emulsified composition of the present invention does not hinder the emulsifier form by containing these components.
【００１９】上記のようにして乳化組成物中の界面活性
剤の配合量を少なくすることが可能となれば、化粧料に
おいては界面活性剤に由来する化粧崩れや安全性の低下
などの問題を、また、皮膚外用医薬品においては界面活
性剤に由来する皮膚内貯留性の損失、安全性の低下等の
問題を、それぞれの乳化組成物の有する本来的な機能や
使用性を低下させることなく有効に解決することが可能
となる。If it is possible to reduce the amount of the surfactant incorporated in the emulsion composition as described above, cosmetics may suffer from problems such as makeup deterioration and safety deterioration due to the surfactant. In addition, in the external drug for skin, it is effective against the problems such as the loss of storability in the skin due to the surfactant and the decrease in safety without deteriorating the intrinsic function and usability of each emulsion composition. Can be solved.
【００２０】[0020]
【発明の実施の形態】以下に本発明の実施の形態を説明
する。 （１）本発明の乳化組成物 本発明の乳化組成物は、(1)シュードモナス・エロディ
アが産生するグルコース、グルクロン酸及びラムノース
を構成糖とする多糖類と、(2)揮発性油剤と、(3)カルボ
ニル基を有する水不溶性高分子粉末と、を含有すること
を特徴とする。Embodiments of the present invention will be described below. (1) Emulsified composition of the present invention The emulsified composition of the present invention comprises (1) a polysaccharide produced by Pseudomonas erodia, which has glucose, glucuronic acid and rhamnose as a constituent sugar, and (2) a volatile oil agent. 3) A water-insoluble polymer powder having a carbonyl group.
【００２１】本発明に用いるシュードモナス・エロディ
アが産生するグルコース、グルクロン酸及びラムノース
を構成糖とする多糖類については上述した通りである。
この様な本発明に用いる多糖類を得るためには、例え
ば、前記多糖類を産生する能力を有する微生物を培養し
その培養物から目的とする多糖類を分離精製すればよ
い。より具体的には、シュードモナス・エロディア等を
一般的な発酵原液に接種し通常の発酵を行い、得られる
発酵産物より上記多糖類を遠心分離やクロマトグラフィ
ー等の通常の方法により分離精製することで上記多糖類
を製造することができる。本発明には、上記多糖類を含
有する培養物あるいは精製途中の粗製物等を用いること
も可能である。また、上記多糖類は製品として市販され
ているものも多いのでこれらを本発明に用いることも可
能である。例えば、本発明に好ましく用いられる上記一
般式（Ｉ）に表される多糖類としては、シュードモナス
・エロディアの発酵産物であるジェランガムが、米国メ
ルク社よりケルコゲルの商品名で市販されている。The polysaccharide produced by Pseudomonas erodia used in the present invention, which has glucose, glucuronic acid and rhamnose as constituent sugars, is as described above.
In order to obtain such a polysaccharide used in the present invention, for example, a microorganism having the ability to produce the above-mentioned polysaccharide may be cultured and the desired polysaccharide may be separated and purified from the culture. More specifically, Pseudomonas erodia etc. is inoculated into a general fermentation stock solution to carry out ordinary fermentation, and the above-mentioned polysaccharide is separated and purified from the obtained fermentation product by a usual method such as centrifugation or chromatography. The above-mentioned polysaccharide can be produced. In the present invention, it is also possible to use a culture containing the above-mentioned polysaccharide or a crude product in the process of purification. Since many of the above-mentioned polysaccharides are commercially available as products, these can be used in the present invention. For example, gellan gum, which is a fermentation product of Pseudomonas erodia, is commercially available from Merck & Co., Inc. under the trade name of Kelcogel as a polysaccharide represented by the above general formula (I) and preferably used in the present invention.
【００２２】上記多糖類の本発明の乳化組成物における
好ましい含有量は０．１〜５重量％であり、０．５〜４
重量％の含有量とすることがより好ましく、１〜３重量
％の含有量とすることがさらに好ましい。The preferred content of the above-mentioned polysaccharide in the emulsion composition of the present invention is 0.1 to 5% by weight, and 0.5 to 4
The content is more preferably the content by weight, and further preferably the content is 1 to 3% by weight.
【００２３】本発明の乳化組成物に用いる揮発性油剤と
しては、上述のように室温で揮散する性質を有する油剤
であれば特に制限されずに挙げることができる。室温で
揮散する油剤として、具体的には、大気圧下における沸
点が２００℃未満である油剤を挙げることができる。こ
の様な揮発性油剤は、化粧料や皮膚外用医薬品に一般に
用いられており、これらを本発明に用いることが可能で
ある。The volatile oil agent used in the emulsified composition of the present invention is not particularly limited as long as it is an oil agent having a property of volatilizing at room temperature as described above. Specific examples of the oil agent that evaporates at room temperature include an oil agent having a boiling point of less than 200 ° C. under atmospheric pressure. Such a volatile oil agent is generally used in cosmetics and external medicines for skin, and these can be used in the present invention.
【００２４】上記揮発性油剤として、より具体的には、
粘度０．１〜１０センチストークスのジメチルポリシロ
キサン、３〜６量体の環状ジメチルポリシロキサン、炭
素数２０未満の分岐の炭化水素及び総炭素数１２未満の
エステル等を挙げることができる。さらに、炭素数２０
未満の分岐炭化水素としては、イソノナン、イソデカ
ン、イソウンデカン、イソドデカン、炭素数２０未満の
ポリイソブテンやこれらの数種の混合物である軽質流動
イソパラフィン等を、総炭素数１２未満のエステルとし
ては、エチルイソオクタネート、メチルイソオクタネー
ト、アジピン酸ジエチル等を挙げることができる。本発
明の乳化組成物は、これらの１種を単独で又は２種以上
を混合物として含有することができる。More specifically, as the volatile oil agent,
Examples thereof include dimethylpolysiloxane having a viscosity of 0.1 to 10 centistokes, cyclic dimethylpolysiloxane having a hexamer to hexamer, branched hydrocarbon having less than 20 carbon atoms, and ester having less than 12 total carbon atoms. Furthermore, carbon number 20
Examples of branched hydrocarbons having a carbon number of less than are isononane, isodecane, isoundecane, isododecane, polyisobutene having a carbon number of less than 20, and light liquid isoparaffin which is a mixture of several types thereof. Octanoate, methyl isooctanoate, diethyl adipate and the like can be mentioned. The emulsified composition of the present invention can contain one of these alone or two or more as a mixture.
【００２５】これらの揮発性油剤は通常の製造方法に従
って製造することも可能であるが、製品として市販され
ているものも多いのでこれらを本発明に用いることも可
能である。この様な市販品としては、例えば、粘度０．
１〜１０センチストークスのジメチルポリシロキサンと
してシリコーンＫＦ９６−１ｃ．ｓ．（信越化学株式会
社製）等を、３〜６量体の環状ジメチルポリシロキサン
としてシリコーンＤＣ３４５（東レ・ダウ・コーニング
株式会社製）等を、炭素数が２０未満程度の分岐の炭化
水素では軽質流動イソパラフィンとしてシェルソル７１
（松本製薬株式会社製）、アイソパーＧ（エクソン化学
株式会社製）等を挙げることができる。These volatile oil agents can be produced by a usual production method, but since many of them are commercially available, they can be used in the present invention. As such a commercial product, for example, a viscosity of 0.
Silicone KF96-1c.as dimethylpolysiloxane of 1 to 10 centistokes. s. (Manufactured by Shin-Etsu Chemical Co., Ltd.), etc. as a 3 to 6-mer cyclic dimethyl polysiloxane such as Silicone DC345 (manufactured by Toray Dow Corning Co., Ltd.), etc. Shell Sol 71 as isoparaffin
(Made by Matsumoto Pharmaceutical Co., Ltd.), Isopar G (made by Exxon Chemical Co., Ltd.) and the like.
【００２６】本発明の乳化組成物における、上記揮発性
油剤の好ましい含有量は、１〜９０重量％であり、５〜
８０重量％の含有量とすることがより好ましく、１０〜
７０重量％の含有量とすることがさらに好ましい。In the emulsion composition of the present invention, the content of the volatile oil agent is preferably 1 to 90% by weight,
The content is more preferably 80% by weight,
More preferably, the content is 70% by weight.
【００２７】本発明の乳化組成物に用いるカルボニル基
を有する水不溶性高分子粉末としては、分子構造中にカ
ルボニル基を有する高分子化合物であって水に不溶性の
粉末であれば特に制限されないが、具体的には、水不溶
性多糖類粉末、水不溶性タンパク質粉末、ポリアミド粉
末、アクリル樹脂粉末等を挙げることができる。これら
のカルボニル基を有する水不溶性高分子粉末は、１種が
単独で又は２種以上が混合物として本発明の乳化組成物
に用いられる。The water-insoluble polymer powder having a carbonyl group used in the emulsion composition of the present invention is not particularly limited as long as it is a polymer compound having a carbonyl group in its molecular structure and is a water-insoluble powder. Specifically, water-insoluble polysaccharide powder, water-insoluble protein powder, polyamide powder, acrylic resin powder and the like can be mentioned. These water-insoluble polymer powders having a carbonyl group are used singly or as a mixture of two or more kinds in the emulsion composition of the present invention.
【００２８】また、上記カルボニル基を有する水不溶性
高分子粉末として、より具体的には水不溶性多糖類粉末
として、セルロース粉末、デンプン粉末等を、水不溶性
タンパク質粉末として、シルクパウダー、牛皮革粉末等
を、ポリアミド粉末としてナイロンパウダー等をアクリ
ル樹脂粉末として、アクリル酸、メタアクリル酸及びこ
れらのエステルのポリマー粉末やこれらの共重合体粉
末、例えば、メチルアクリレートポリマー、エチルアク
リレートポリマー、メチルメタアクリレートポリマー、
エチルメタアクリレートポリマー、アクリル酸メチル−
メタアクリル酸メチルコポリマー、メタアクリル酸メチ
ル−エチレングリコールジメタアクリレートコポリマー
等の粉末を挙げることができる。Further, as the above-mentioned water-insoluble polymer powder having a carbonyl group, more specifically, as water-insoluble polysaccharide powder, cellulose powder, starch powder, etc., as water-insoluble protein powder, silk powder, cowhide powder, etc. The polyamide powder, nylon powder or the like as acrylic resin powder, acrylic acid, methacrylic acid and polymer powders of these esters and copolymer powders thereof, for example, methyl acrylate polymer, ethyl acrylate polymer, methyl methacrylate polymer,
Ethyl methacrylate polymer, methyl acrylate-
Powders such as a methyl methacrylate copolymer and a methyl methacrylate-ethylene glycol dimethacrylate copolymer can be mentioned.
【００２９】さらに、これらのうちでもセルロース粉
末、シルクパウダー、牛皮革粉末等が本発明の乳化組成
物においてより好ましく用いられる。上記本発明に用い
るカルボニル基を有する水不溶性高分子粉末は、通常の
製造方法に従って製造することも可能であるが、製品と
して市販されているものも多いのでこれらを本発明に用
いることも可能である。この様な市販品としては、例え
ば、シルクパウダーとしてシルクパウダー（絹開発研究
所製）等を、牛皮革粉末としてプロテインパウダー（出
光石油化学（株）製）等を、ナイロンパウダーとして東
レナイロンパウダーＳＰ−５００（東レ（株）製）等
を、メチルメタアクリレートポリマーとしてジュリマー
ＭＢ−１（日本純薬製）等を、メタアクリル酸メチル−
エチレングリコールジメタアクリレートコポリマーとし
てチュウクウビーズ（松本油脂製薬製）等を挙げること
ができる。Furthermore, among these, cellulose powder, silk powder, cowhide powder and the like are more preferably used in the emulsified composition of the present invention. The water-insoluble polymer powder having a carbonyl group used in the present invention can be produced according to a usual production method, but since many of them are commercially available as products, they can be used in the present invention. is there. Examples of such commercially available products include silk powder (made by Silk Development Laboratory) as silk powder, protein powder (made by Idemitsu Petrochemical Co., Ltd.) as cowhide powder, and Toray nylon powder SP as nylon powder. -500 (manufactured by Toray Industries, Inc.) and the like, methyl methacrylate polymer such as Julimer MB-1 (manufactured by Nippon Pure Chemical Co., Ltd.), and methyl methacrylate-
Examples of ethylene glycol dimethacrylate copolymers include Cyukyu beads (Matsumoto Yushi-Seiyaku Co., Ltd.).
【００３０】本発明の乳化組成物における上記カルボニ
ル基を有する水不溶性高分子粉末の好ましい含有量は、
０．１〜２０重量％であり、１〜１５重量％の含有量で
あることがより好ましく、３〜１０重量％の含有量であ
ることがさらに好ましい。The preferred content of the above water-insoluble polymer powder having a carbonyl group in the emulsion composition of the present invention is
The content is from 0.1 to 20% by weight, more preferably from 1 to 15% by weight, even more preferably from 3 to 10% by weight.
【００３１】本発明の乳化組成物は、上記多糖類、揮発
性油剤、カルボニル基を有する水不溶性高分子粉末とと
もに、通常の乳化組成物が含有する基剤成分を含有し、
さらに、界面活性剤や各種用途、目的等にあわせて適宜
選択される各種成分を任意に含有する。これら多糖類、
揮発性油剤、カルボニル基を有する水不溶性高分子粉末
以外の各種成分については、本発明の乳化組成物の用
途、目的等により様々であり、これらの詳細な説明は後
述の化粧料、皮膚外用医薬品の各組成物毎に行うことと
する。また、これら各種成分は、本発明の効果を損なわ
ない範囲の含有量で本発明の乳化組成物に含有すること
が可能である。なお、本発明の乳化組成物における基剤
成分は通常の乳化組成物の基剤成分と同様に水相成分と
油相成分とからなるが、本発明の乳化組成物においては
この油相成分を上記揮発性油剤のみで構成してもよい
し、あるいは上記揮発性油剤とそれ以外の油剤との組み
合わせで構成してもよい。The emulsion composition of the present invention contains the above-mentioned polysaccharide, volatile oil agent, water-insoluble polymer powder having a carbonyl group, and a base component which is contained in a usual emulsion composition,
Further, it optionally contains a surfactant and various components appropriately selected according to various uses and purposes. These polysaccharides,
The volatile oil agent, various components other than the water-insoluble polymer powder having a carbonyl group, various depending on the use, purpose, etc. of the emulsion composition of the present invention, a detailed description of these cosmetics, skin external drug The above is performed for each composition. In addition, these various components can be contained in the emulsion composition of the present invention in a content within a range that does not impair the effects of the present invention. The base component in the emulsified composition of the present invention is composed of an aqueous phase component and an oil phase component like the base component of a usual emulsified composition, but in the emulsified composition of the present invention, the oil phase component is It may be composed only of the above volatile oil agent, or may be composed of a combination of the above volatile oil agent and other oil agents.
【００３２】また、本発明の乳化組成物において界面活
性剤の配合は上述のように任意であり、本発明において
は上記多糖類、揮発性油剤、カルボニル基を有する水不
溶性高分子粉末を含有することで通常の乳化組成物より
少ない量の界面活性剤の配合で良好な乳化物を得ること
ができる。さらに、本発明においては必要に応じて界面
活性剤を含有しない乳化組成物を作製することも可能で
ある。In the emulsion composition of the present invention, the compounding of the surfactant is optional as described above, and in the present invention, the polysaccharide, the volatile oil agent and the water-insoluble polymer powder having a carbonyl group are contained. As a result, a good emulsion can be obtained by blending a smaller amount of the surfactant than the usual emulsion composition. Further, in the present invention, it is possible to prepare an emulsion composition containing no surfactant, if necessary.
【００３３】この様な本発明の乳化組成物は、上記多糖
類を水相成分に、揮発性油剤を油相成分に、また、カル
ボニル基を有する水不溶性高分子粉末をそのどちらか
に、それぞれ配合する以外は、通常の乳化組成物と同様
にして、例えば、揮発性油剤を配合した油相成分と上記
多糖類を配合した水相成分とをそれぞれ７０〜９０℃程
度に加熱し、このどちらかにカルボニル基を有する水不
溶性高分子粉末を分散させ、これらを混合し撹拌乳化さ
せ、その後、冷却する等の方法で製造することができ
る。In such an emulsion composition of the present invention, the above-mentioned polysaccharide is used as an aqueous phase component, a volatile oil agent is used as an oil phase component, and a water-insoluble polymer powder having a carbonyl group is added to either of them. Except for blending, in the same manner as a usual emulsion composition, for example, an oil phase component blended with a volatile oil agent and an aqueous phase component blended with the above-mentioned polysaccharide are heated to about 70 to 90 ° C., respectively. A water-insoluble polymer powder having a crab carbonyl group is dispersed, these are mixed, emulsified with stirring, and then cooled.
【００３４】この様な本発明の乳化組成物として、具体
的には、化粧料や皮膚外用医薬品等を挙げることができ
る。以下、本発明の化粧料、皮膚外用医薬品の順にそれ
ぞれ実施の形態を説明する。Specific examples of such an emulsified composition of the present invention include cosmetics and external medicines for skin. The embodiments will be described below in the order of the cosmetic of the present invention and the external skin drug.
【００３５】（２）本発明の化粧料 本発明の乳化組成物が適用可能な化粧料としては、乳化
型の剤形が適用できる化粧料であれば特に制限されるも
のではなく、例えば、クリーム等の基礎化粧品、ファン
デーション等のメークアップ化粧料、ヘアクリーム等の
頭髪化粧料、ボディークリーム等の全身用化粧料を挙げ
ることが可能である。(2) Cosmetic of the present invention The cosmetic to which the emulsion composition of the present invention is applicable is not particularly limited as long as it is a cosmetic to which an emulsion type dosage form can be applied. Examples thereof include basic cosmetics such as, makeup cosmetics such as foundations, hair cosmetics such as hair creams, and whole-body cosmetics such as body creams.
【００３６】上述のように本発明の化粧料においては、
通常より少ない量の界面活性剤の配合であるいは界面活
性剤を配合せずに良好な乳化物が得られるが、これによ
り従来の乳化型化粧料において問題とされていた界面活
性剤に由来する化粧崩れや安全性の低下などを解決する
ことができる。また、本発明の化粧料はさっぱりした使
用感を有しており、従来の有機高分子ゲル化剤を用いた
乳化組成物で問題とされていた手に取ったときのボロボ
ロ感も改善され使用性がよくなっている。As described above, in the cosmetic of the present invention,
A good emulsion can be obtained by adding a surfactant in an amount smaller than usual or without adding a surfactant, which results in a cosmetic derived from a surfactant which has been a problem in conventional emulsified cosmetics. It is possible to solve a collapse and a decrease in safety. In addition, the cosmetic of the present invention has a refreshing feeling of use, and the tattered feeling when taken by hand, which has been a problem in the emulsified composition using the conventional organic polymer gelling agent, is improved and used. I'm getting better.
【００３７】本発明の化粧料を基礎化粧料として用いれ
ば、クレンジング料等では界面活性剤が減量されている
にもかかわらず従来のものと遜色のない化粧料落とし作
用を発揮することができる。ファンデーションとして用
いれば、パウダー等での化粧抑えのいらない、いわゆる
オールインワンファンデーションが化粧持ちのよいもの
として提供できる。また、頭髪化粧料として用いれば、
べとつき感のない整髪料が提供できる。この様な本発明
の化粧料のうち、本発明の乳化組成物がより好ましく適
用されるのはクレンジング料等の化粧落とし料である。When the cosmetic of the present invention is used as a basic cosmetic, a cleansing agent or the like can exhibit a cosmetic-removing effect comparable to the conventional one, even though the amount of the surfactant is reduced. When used as a foundation, a so-called all-in-one foundation, which does not require makeup control with powder or the like, can be provided as a makeup-retaining product. If used as a hair cosmetic,
It is possible to provide a hair styling product that is not sticky. Among such cosmetics of the present invention, the emulsified composition of the present invention is more preferably applied to makeup removers such as cleansing agents.
【００３８】また、本発明の化粧料は、上記多糖類、揮
発性油剤、カルボニル基を有する水不溶性高分子粉末
と、以下に挙げるそれ以外の各種成分とを用いて通常の
化粧料の製造方法に従って製造することができる。Further, the cosmetic of the present invention comprises the above-mentioned polysaccharide, volatile oil agent, water-insoluble polymer powder having a carbonyl group, and various other ingredients listed below, which are conventional methods for producing cosmetics. Can be manufactured according to.
【００３９】本発明の化粧料に、上記多糖類、揮発性油
剤、カルボニル基を有する水不溶性高分子粉末以外に配
合される成分としては、通常、化粧料に配合される水；
ワセリン、スクワラン、マイクロクリスタリンワックス
等の炭化水素類、ホホバ油、ゲイロウ、カルナウバワッ
クス等のエステル類；オリーブ油、牛脂等のトリグリセ
ライド類；セタノール、オレイルアルコール、ステアリ
ルアルコール等の高級アルコール類；ステアリン酸、オ
レイン酸等の高級脂肪酸類；グリセリン、プロピレング
リコール、１，３−ブタンジオール等の多価アルコール
類；エタノール、プロパノール等の低級アルコール類；
不揮発性のシリコーン；脂肪酸モノグリセライド、ポオ
キシエチレン硬化ヒマシ油等のノニオン界面活性剤；ラ
ウリル硫酸ナトリウム、アルキルスルホコハク酸エステ
ル等のアニオン界面活性剤；４級アルキルアミン塩等の
カチオン界面活性剤；アルキルベタイン等の両性界面活
性剤；アラビアゴム、カルボキシビニルポリマー等の増
粘剤；パラベン、グルコン酸クロルヘキシジン等の防腐
剤；タルク、シリカゲル、酸化チタン等の粉体類；トコ
フェロール、ブチルヒドロキシトルエン等の抗酸化剤；
パラアミノ安息香酸誘導体、ベンゾフェノン誘導体等の
紫外線吸収剤；ポリエチレングリコール、ヒアルロン酸
等の保湿剤；グリチルリチン酸ジカリウム等の抗炎症
剤；クエン酸塩、酢酸塩等のｐＨ調整剤；キレート剤；
香料；色素；胎盤抽出物、朝鮮人参エキス、ステロール
配糖体等の各種目的に応じた薬効成分などが挙げられ
る。As the components to be added to the cosmetic of the present invention other than the above-mentioned polysaccharide, volatile oil agent and water-insoluble polymer powder having a carbonyl group, water usually added to cosmetics;
Hydrocarbons such as petrolatum, squalane, microcrystalline wax, etc., esters such as jojoba oil, gaylow, carnauba wax; triglycerides such as olive oil, beef tallow; higher alcohols such as cetanol, oleyl alcohol, stearyl alcohol; stearic acid, Higher fatty acids such as oleic acid; polyhydric alcohols such as glycerin, propylene glycol and 1,3-butanediol; lower alcohols such as ethanol and propanol;
Nonvolatile silicones; nonionic surfactants such as fatty acid monoglyceride and pooxyethylene hydrogenated castor oil; anionic surfactants such as sodium lauryl sulfate and alkyl sulfosuccinates; cationic surfactants such as quaternary alkylamine salts; alkyl betaines Amphoteric surfactants such as; gum arabic, thickeners such as carboxyvinyl polymer; preservatives such as paraben and chlorhexidine gluconate; powders such as talc, silica gel and titanium oxide; antioxidants such as tocopherol and butylhydroxytoluene Agent;
UV absorbers such as para-aminobenzoic acid derivatives and benzophenone derivatives; moisturizers such as polyethylene glycol and hyaluronic acid; anti-inflammatory agents such as dipotassium glycyrrhizinate; pH adjusters such as citrate and acetate; chelating agents;
Fragrances; pigments; placental extracts, ginseng extracts, sterol glycosides, and other medicinal components suitable for various purposes.
【００４０】（３）本発明の皮膚外用医薬品 本発明の乳化組成物が適用可能な皮膚外用医薬品として
は、乳化型の剤形が適用できる皮膚外用医薬品であれば
特に制限されるものではない。本発明の皮膚外用医薬品
においては、通常より少ない量の界面活性剤の配合であ
るいは界面活性剤を配合せずに良好な乳化物が得られる
が、これにより従来の乳化型の皮膚外用医薬品において
問題とされていた界面活性剤に由来する皮膚内貯留性の
損失、安全性の低下等を解決することができる。また、
界面活性剤を含有しない系とすれば、栓塞貼付下での安
全性が非常に大事な貼付剤等のマトリックスにも好適に
適用できる。さらに、上記化粧料と同様、使用性等の改
善もなされている。(3) External skin drug of the present invention The external skin drug to which the emulsion composition of the present invention can be applied is not particularly limited as long as it is an external skin drug to which an emulsion type dosage form can be applied. In the skin external preparation of the present invention, a good emulsion can be obtained by adding a surfactant in a smaller amount than usual or without adding a surfactant, but this causes a problem in conventional emulsification type skin external preparations. It is possible to solve the problems such as the loss of storability in the skin and the decrease in safety due to the said surfactants. Also,
If the system does not contain a surfactant, it can be suitably applied to a matrix such as a patch, which is very important in safety under application of a plug. Further, similar to the above cosmetics, the usability and the like have been improved.
【００４１】本発明の皮膚外用医薬品としては、例え
ば、抗ヒスタミン剤やステロイドホルモン等を配合した
痒み止め薬、殺菌剤や抗生物質を配合した化膿防止薬、
抗炎症剤を配合した抗炎症薬、抗真菌剤を配合した水虫
治療薬やタムシ治療薬などを挙げることができる。この
様に本発明の皮膚外用医薬品には、上記多糖類、揮発性
油剤、カルボニル基を有する水不溶性高分子粉末以外の
成分として、抗ヒスタミン剤、ステロイドホルモン、殺
菌剤、抗生物質、抗炎症剤、抗真菌剤等の各種薬効成分
が適宜選択されて配合される。Examples of the external skin drug of the present invention include an antipruritic drug containing an antihistamine, a steroid hormone and the like, an antipyretic drug containing a bactericide and an antibiotic,
An anti-inflammatory drug containing an anti-inflammatory agent, a remedy for athlete's foot or a beetle containing an anti-fungal agent, and the like can be mentioned. Thus, the skin external medicine of the present invention, the above-mentioned polysaccharides, volatile oil agents, as components other than water-insoluble polymer powder having a carbonyl group, antihistamines, steroid hormones, fungicides, antibiotics, anti-inflammatory agents, anti- Various medicinal ingredients such as fungal agents are appropriately selected and mixed.
【００４２】また、本発明の皮膚外用医薬品は、これら
の成分の他に通常皮膚外用医薬品に適宜配合されるエイ
ゾン等の経皮吸収促進剤や、上記化粧料の配合成分とし
て詳述した、水、炭化水素類、エステル類、トリグリセ
ライド類、高級アルコール類、高級脂肪酸類、多価アル
コール類、界面活性剤、低級アルコール類、増粘剤、防
腐剤、粉体類、抗酸化剤、紫外線吸収剤、ｐＨ調整剤、
キレート剤、色素等の各種成分を用いて通常の皮膚外用
医薬品の製造方法に従って製造することができる。In addition to these components, the external preparation for skin of the present invention contains, in addition to these components, a percutaneous absorption enhancer such as Azone, which is usually blended appropriately with external preparations for skin, and water, which has been described in detail as a blending component of the above cosmetics. , Hydrocarbons, esters, triglycerides, higher alcohols, higher fatty acids, polyhydric alcohols, surfactants, lower alcohols, thickeners, preservatives, powders, antioxidants, UV absorbers , PH adjuster,
It can be produced according to a usual method for producing a skin external medicine by using various components such as a chelating agent and a dye.
【００４３】[0043]
【実施例】以下に、本発明の実施例を説明する。まず、
化粧料の実施例について説明する。なお、化粧料の実施
例に用いる配合量は全て重量部である。また、以下の実
施例にはシュードモナス・エロディアが産生するグルコ
ース、グルクロン酸及びラムノースを構成糖とする多糖
類としてジュランガムを用いたが、これらは全てメルク
社製のケルコゲルであった。Embodiments of the present invention will be described below. First,
Examples of cosmetics will be described. The amounts of the cosmetics used in the examples are all parts by weight. Further, in the following examples, duran gum was used as a polysaccharide having glucose, glucuronic acid and rhamnose as constituent sugars produced by Pseudomonas erodia, but these were all kelcogels manufactured by Merck.
【００４４】[0044]
【実施例１〜４】 クリーム 表１の処方に基づいてクリームを作製した。すなわち、
表１に示すＡ成分、Ｂ成分をそれぞれ８０℃に加熱溶解
した後、Ｂ成分にＣ成分を分散させ、次いで撹拌しなが
らこれにＡ成分を徐々に加えて乳化し、冷却してクリー
ムを得た。Examples 1 to 4 Cream Creams were prepared based on the formulations shown in Table 1. That is,
Each of the components A and B shown in Table 1 was heated and dissolved at 80 ° C., then the component C was dispersed in the component B, and then the component A was gradually added to this while stirring to emulsify and cool to obtain a cream. It was
【００４５】また、比較のために、実施例２のクリーム
の配合成分中、ケルコゲルを寒天に置換したクリーム
（比較例１）、ケルコゲルをゼラチンに置換したクリー
ム（比較例２）、ケルコゲルをＰＯＥ（２０）オレイル
エーテルに置換したクリーム（比較例３）、ケルコゲル
を寒天に、結晶セルロースを水にそれぞれ置換したクリ
ーム（比較例４）、揮発性油剤を流動パラフィンに置換
したクリーム（比較例５）を、上記と同様の製造方法で
それぞれ作製した。For comparison, among the ingredients of the cream of Example 2, the cream in which the kercogel was replaced with agar (Comparative Example 1), the cream in which the kercogel was replaced with gelatin (Comparative Example 2), and the kelcogel with POE ( 20) A cream in which oleyl ether was substituted (Comparative Example 3), a cream in which Kercogel was replaced with agar and crystalline cellulose was substituted with water (Comparative Example 4), and a cream in which volatile oil was substituted with liquid paraffin (Comparative Example 5). Were manufactured by the same manufacturing method as described above.
【００４６】[0046]
【表１】 [Table 1]
【００４７】[0047]
【実施例５〜８】 クリーム 表２の処方に基づいてクリームを作製した。すなわち、
表２に示すＡ成分、Ｂ成分をそれぞれ８０℃に加熱溶解
した後、Ｂ成分にＣ成分を分散させ、次いで撹拌しなが
らこれにＡ成分を徐々に加えて乳化し、冷却してクリー
ムを得た。Examples 5 to 8 Cream Creams were prepared based on the formulations shown in Table 2. That is,
The components A and B shown in Table 2 are heated and dissolved at 80 ° C., respectively, and then the component C is dispersed in the component B, and then the component A is gradually added to this while stirring to emulsify and cool to obtain a cream. It was
【００４８】[0048]
【表２】 [Table 2]
【００４９】＜本発明のクリームの評価＞上記各実施例
及び各比較例で得られたクリームを用いて、使用性・使
用感の試験、化粧持ち試験及びクレンジング試験を行
い、本発明のクリームを評価した。<Evaluation of Cream of the Present Invention> Using the creams obtained in each of the above Examples and Comparative Examples, a usability / feeling test, a makeup retention test and a cleansing test were conducted to obtain the cream of the present invention. evaluated.
【００５０】（１）使用性・使用感の試験 上記実施例１〜８及び比較例１〜４で得られたクリーム
の使用性及び使用感についての官能評価を行った。専門
パネラー４名に、各クリームを使用してもらい、これら
のクリームについて、のびの良さ、取れ易さ（以上使用
性の評価項目）、しっとり感、さっぱり感（以上使用感
の評価項目）の４項目を非常によい（５点）〜非常に悪
い（１点）の５段階で評価してもらい、４人の平均値を
そのクリームの評点とした。結果を表３に示す。(1) Test of usability and usability The creams obtained in Examples 1 to 8 and Comparative Examples 1 to 4 were sensory evaluated for usability and usability. Four expert panelists use each cream, and these creams have good spreadability, ease of removal (evaluation items for usability), moist feeling, and refreshing feeling (evaluation items for usability). The item was evaluated on a scale of 5 from very good (5 points) to very bad (1 point), and the average value of 4 persons was used as the score of the cream. The results are shown in Table 3.
【００５１】[0051]
【表３】 [Table 3]
【００５２】この結果より、実施例のクリームは、比較
例で得られた本発明の乳化組成物の多糖類を従来の有機
高分子ゲル化剤や界面活性剤に置換したクリームやさら
に水不溶性高分子粉末を含有しないクリームに比べて、
使用性に優れていることが明らかである。また、使用感
に関していえば、実施例のクリームは、比較例で得られ
た本発明の乳化組成物の多糖類を界面活性剤に置換した
クリームや従来の有機高分子ゲル化剤を用いた界面活性
剤フリーのクリームに比べて優れており、本発明の乳化
組成物の多糖類を従来の有機高分子ゲル化剤に置換した
クリームに比べて同等かそれ以上に優れていることがわ
かる。From these results, it can be seen that the creams of the examples are creams in which the polysaccharide of the emulsion composition of the present invention obtained in the comparative example is replaced by a conventional organic polymer gelling agent or a surfactant, and further the water-insoluble high Compared to the cream that does not contain molecular powder,
It is clear that it is excellent in usability. Further, regarding the feeling of use, the creams of Examples are the ones obtained by replacing the polysaccharide of the emulsion composition of the present invention obtained in Comparative Example with a surfactant or an interface using a conventional organic polymer gelling agent. It can be seen that the cream is superior to the active agent-free cream and is equal to or superior to the cream in which the polysaccharide of the emulsion composition of the present invention is replaced with the conventional organic polymer gelling agent.
【００５３】（２）化粧持ち試験 上記実施例１〜８及び比較例１〜４で得られたクリーム
について、このクリームの上に塗布されるメークアップ
化粧料の化粧持ちに対する作用を調べた。すなわち、各
クリームを上腕部に塗り、その上に後述の比較例１０と
同様にして得られたクリームファンデーションを塗布し
て、流水下、流動パラフィン塗布下での擦りに対しての
崩れ難さを専門パネラー４名に評価してもらった。評価
は、化粧持ちが非常に良いを５点とし化粧持ちが非常に
悪いを１点とした５段階評価で、４人の平均値をそのク
リームの評点とした。結果を表４に示す。(2) Makeup lasting test With respect to the creams obtained in the above Examples 1 to 8 and Comparative Examples 1 to 4, the effect of the makeup cosmetics applied on the creams to makeup lasting was examined. That is, each cream was applied to the upper arm, and a cream foundation obtained in the same manner as in Comparative Example 10 described later was applied to the upper arm to make it hard to collapse under running water and rubbing under application of liquid paraffin. We had four specialist panelists evaluate us. The evaluation was carried out on a 5-point scale, with a very good make-up lasting 5 points and a very poor make-up lasting 1 point, and the average value of 4 persons was used as the score of the cream. The results are shown in Table 4.
【００５４】[0054]
【表４】 [Table 4]
【００５５】この結果から、界面活性剤を含有しない実
施例のクリームは、界面活性剤を含有する比較例３のク
リームに比べて化粧持ちが著しく改善されていることが
わかる。また、「のび」と「取れ易さ」が改善された実
施例のクリームでは密着性が優れるため、比較例１、
２、４で得られた本発明の乳化組成物の多糖類、水不溶
性高分子粉末等を含有しない界界面活性剤フリーのクリ
ームに比べてもより化粧持ちが向上していることもわか
る。From these results, it can be seen that the creams of Examples containing no surfactant have significantly improved makeup retention as compared with the cream of Comparative Example 3 containing a surfactant. Further, since the creams of Examples having improved "spread" and "easiness of removal" have excellent adhesiveness, Comparative Example 1,
It can also be seen that the longevity of the cosmetic composition is further improved as compared with the cream containing no surfactant and free of the polysaccharide and the water-insoluble polymer powder of the emulsion composition of the present invention obtained in Nos. 2 and 4.
【００５６】（３）クレンジング試験 上記実施例１〜８及び比較例５で得られたクリームのク
レンジング料としての評価を行った。すなわち、後述の
比較例１１と同様にして得られたクリームファンデーシ
ョンを上腕内側部に塗布し、その上に上記各クリームを
塗布して、クリームファンデーションの拭き取りを行っ
た。その際のクリームファンデーションの落ち具合を専
門パネラー４名に肉眼で、非常によく落ちている（５
点）〜ほとんど落ちていない（１点）の基準に従って５
段階に評価してもらい、４人の平均値をそのクリームの
クレンジング性の評点とした。(3) Cleansing Test The creams obtained in the above Examples 1 to 8 and Comparative Example 5 were evaluated as a cleansing agent. That is, the cream foundation obtained in the same manner as in Comparative Example 11 described below was applied to the inner side of the upper arm, and each of the above creams was applied thereon to wipe off the cream foundation. The degree of cream foundation loss at that time was visually well noticed by 4 specialized panelists (5
5) according to the criteria of (point) to almost no drop (1 point)
The cream was evaluated in stages, and the average value of the four persons was used as the cleansing score of the cream.
【００５７】また、クリームを拭き取った後、ぬるま湯
のみで洗浄してクリームの残り具合を、ほとんど残らな
い（５点）〜ほとんど落ちていない（１点）の基準に従
って５段階に評価してもらい、４人の平均値をそのクリ
ームのウォッシュオフ性の評点とした。結果を表５に示
す。After the cream was wiped off, the cream was washed only with lukewarm water, and the remaining condition of the cream was evaluated on a scale of 5 according to the criteria of almost no residue (5 points) to almost no residue (1 point). The average value of 4 persons was used as the score of the wash-off property of the cream. Table 5 shows the results.
【００５８】[0058]
【表５】 [Table 5]
【００５９】この結果から、実施例のクリームは、本発
明の乳化組成物の揮発性油剤を流動パラフィンに置換し
たクリームに比べて、クレンジング性に優れ、ウォッシ
ュオフ性については非常に優れていることがわかる。From these results, it can be seen that the creams of Examples have excellent cleansing properties and very excellent wash-off properties as compared with the creams of the emulsified composition of the present invention in which the volatile oil agent is replaced with liquid paraffin. I understand.
【００６０】[0060]
【実施例９〜１２】 クリームファンデーション 表６の処方に基づいてクリームファンデーションを作製
した。すなわち、表６に示すＡ成分、Ｂ成分をそれぞれ
８０℃に加熱溶解した後、Ｂ成分にＣ成分を分散させ、
次いで撹拌しながらこれにＡ成分を徐々に加えて乳化
し、冷却してクリームファンデーションを得た。なお、
表中の成分でプロテインパウダーとは、出光石油化学
（株）製の牛皮革粉末の商品名である。Examples 9 to 12 Cream Foundation Cream foundations were prepared based on the formulations shown in Table 6. That is, the components A and B shown in Table 6 are heated and dissolved at 80 ° C., respectively, and then the component C is dispersed in the component B,
Then, the component A was gradually added to this with stirring to emulsify it and cooled to obtain a cream foundation. In addition,
In the table, protein powder is a trade name of cowhide powder manufactured by Idemitsu Petrochemical Co., Ltd.
【００６１】また、比較のために、実施例９のクリーム
ファンデーションの配合成分中、ケルコゲルを寒天に置
換したクリームファンデーション（比較例６）、ケルコ
ゲルをゼラチンに置換したクリームファンデーション
（比較例７）、ケルコゲルを寒天に、シルクパウダーを
水にそれぞれ置換したクリームファンデーション（比較
例８）、揮発性油剤を流動パラフィンに置換したクリー
ムファンデーション（比較例９）を上記と同様の製造方
法でそれぞれ作製した。さらに、表７に配合成分を示す
従来の水中油ファンデーション（比較例１０）、表８に
配合成分を示す従来の高内相油中水ファンデーション
（比較例１１）を上記と同様の方法で作製して実施例の
クリームファンデーションと比較した。For comparison, among the components of the cream foundation of Example 9, the cream foundation in which the kercogel was replaced with agar (Comparative Example 6), the cream foundation in which the kercogel was replaced with gelatin (Comparative Example 7), and the kercogel A cream foundation (Comparative Example 8) in which silk powder was replaced with water (Comparative Example 8) and a cream foundation (Comparative Example 9) in which the volatile oil was replaced with liquid paraffin were prepared by the same manufacturing method as described above. Further, a conventional oil-in-water foundation having a blending component shown in Table 7 (Comparative Example 10) and a conventional high internal phase water-in-oil foundation having a blending component shown in Table 8 (Comparative Example 11) were prepared in the same manner as above. And compared with the cream foundation of the example.
【００６２】[0062]
【表６】 [Table 6]
【００６３】[0063]
【表７】 [Table 7]
【００６４】[0064]
【表８】 [Table 8]
【００６５】＜本発明のクリームファンデーションの評
価＞上記各実施例及び各比較例で得られたクリームファ
ンデーションを用いて、化粧持ち試験及びオールインワ
ンメークアップ化粧料としての使用性試験を行い、本発
明のクリームファンデーションを評価した。<Evaluation of Cream Foundation of the Present Invention> Using the cream foundations obtained in each of the above Examples and Comparative Examples, a makeup retention test and a usability test as an all-in-one make-up cosmetics were conducted, and the results of the present invention were evaluated. The cream foundation was evaluated.
【００６６】（１）化粧持ち試験 上記実施例９〜１２及び比較例６〜８、１０、１１で得
られたクリームファンデーションについて化粧持ちを調
べた。すなわち、各クリームファンデーションを上腕部
に塗布して、流水下、流動パラフィン塗布下での擦りに
対しての崩れ難さを専門パネラー４名に評価してもらっ
た。評価は、化粧持ちが非常に良いを５点とし化粧持ち
が非常に悪いを１点とした５段階評価で、４人の平均値
をそのクリームファンデーションの評点とした。結果を
表９に示す。(1) Makeup holding test The makeup holding of the cream foundations obtained in Examples 9 to 12 and Comparative Examples 6 to 8, 10 and 11 was examined. That is, each cream foundation was applied to the upper arm portion, and four specialized panelists evaluated the difficulty of breaking it against rubbing under running water and applying liquid paraffin. The evaluation was carried out on a 5-point scale, in which the makeup foundation was very good and the makeup makeup retention was very bad, and the average of 4 persons was used as the score of the cream foundation. Table 9 shows the results.
【００６７】[0067]
【表９】 [Table 9]
【００６８】この結果から、実施例のクリームファンデ
ーションは、界面活性剤を含有する比較例１０のクリー
ムファンデーションに比べて化粧持ちが著しく改善され
ているばかりでなく、比較例６〜８で得られた本発明の
乳化組成物の多糖類、水不溶性高分子粉末等を含有しな
い界面活性剤フリーのクリームファンデーションや比較
例１１の高内相油中水ファンデーションに比べてもより
化粧持ちが向上していることがわかる。From these results, the cream foundations of the examples are not only significantly improved in makeup retention as compared with the cream foundation of the comparative example 10 containing a surfactant but also obtained in the comparative examples 6-8. Compared to the surfactant-free cream foundation of the emulsion composition of the present invention which does not contain polysaccharides, water-insoluble polymer powder, etc. and the high internal phase water-in-oil foundation, the makeup retention is improved. I understand.
【００６９】（２）オールインワンメークアップ化粧料
としての使用性試験 上記実施例９〜１２及び比較例９〜１１で得られたクリ
ームファンデーションについてオールインワンメークア
ップ化粧料としての使用性を化粧仕上がりと化粧性の点
から評価した。すなわち、専門パネラー４名に、上記各
クリームファンデーションをそれぞれ用いて実際にメー
クアップを行った際の仕上がりを、触感と見た目の総合
評価として、化粧抑えのパウダーが全く必要ない（５
点）〜化粧抑えのパウダーが必要（１点）の基準に従っ
て５段階で評価してもらい、４人の平均値をそのクリー
ムファンデーションの化粧仕上がりの評点とした。ま
た、その際のクリームファンデーションの化粧のりやの
びより化粧性を、アンダーメークアップが全く必要ない
（５点）〜アンダーメークアップが必要（１点）の基準
に従って５段階で評価してもらい、４人の平均値をその
クリームファンデーションの化粧性の評点とした。結果
を表１０に示す。(2) Usability test as an all-in-one make-up cosmetic composition The cream foundations obtained in Examples 9 to 12 and Comparative Examples 9 to 11 described above were used as an all-in-one make-up cosmetic composition in terms of cosmetic finish and cosmetic properties. It was evaluated from the point of. That is, as a comprehensive evaluation of the feel and appearance of the finish when actually making up each of the above cream foundations for 4 expert panelists, no makeup-suppressing powder is required (5
(Point) -Evaluation of the makeup level of the cream foundation was made into an average value of four people who were evaluated by 5 grades according to the criteria that a powder for suppressing makeup was required (1 point). In addition, the makeup property of the cream foundation at that time, rather than the paste and spread, was evaluated on a scale of 5 according to the criteria that no undermakeup is required (5 points) to undermakeup (1 point). The average value of people was used as the score of the cosmetic properties of the cream foundation. Table 10 shows the results.
【００７０】[0070]
【表１０】 [Table 10]
【００７１】この結果から、実施例で得られたクリーム
ファンデーションを用いれば、比較例のクリームファン
デーションに比べて、パウダー感のある化粧仕上がりが
得られ、またアンダーメークアップを必要としない程化
粧性がよく、このクリームファンデーションがオールイ
ンワンファンデーションとしての使用性に優れることが
わかる。From these results, when the cream foundations obtained in the examples were used, compared to the cream foundations of the comparative examples, a cosmetic finish with a powdery feeling was obtained, and the makeup properties were so low that no under-makeup was required. It is well understood that this cream foundation has excellent usability as an all-in-one foundation.
【００７２】次に、皮膚外用医薬品の実施例について説
明する。なお、以下の実施例に用いる配合量は重量％で
ある。Next, examples of the external medicine for skin will be described. The blending amount used in the following examples is% by weight.
【００７３】[0073]
【実施例１３〜１６】 皮膚外用剤 表１１の処方に基づいて皮膚外用剤を作製した。すなわ
ち、表１１のＡ成分、Ｂ成分をそれぞれ８０℃に加熱溶
解した後、Ｂ成分にＣ成分を分散させ、次いで撹拌しな
がらこれにＡ成分を徐々に加えて乳化し、冷却して皮膚
外用剤を得た。Examples 13 to 16 Skin external preparations Skin external preparations were prepared based on the formulations in Table 11. That is, the components A and B in Table 11 were heated and dissolved at 80 ° C., respectively, and then the component C was dispersed in the component B, and then the component A was gradually added to this with stirring to emulsify and then cooled to be applied to the external skin. I got an agent.
【００７４】また、比較のために日本薬局方に記載の親
水軟膏と同様にして作製した親水軟にビフォナゾールを
１重量％混ぜて混練りした抗真菌皮膚外用剤（比較例１
２）を作製した。For comparison, an antifungal external preparation for skin (comparative example 1) was prepared by mixing 1% by weight of bifonazole with hydrophilic softener prepared in the same manner as the hydrophilic ointment described in Japanese Pharmacopoeia (Comparative Example 1).
2) was produced.
【００７５】[0075]
【表１１】 [Table 11]
【００７６】＜本発明の皮膚外用剤の評価＞上記実施例
１４で得られた抗真菌皮膚外用剤と比較例１２で得られ
た抗真菌皮膚外用剤を用いて殺菌作用についての試験を
行った。すなわち、前記各抗真菌皮膚外用剤をそれぞれ
１ｇずつ取り、このそれぞれにトリコフィトン・メンタ
グロファイトの分生子を２×１０5個ずつ植え付け、１
４日後に前記分生子の生存の様子を染色により判定し
た。<Evaluation of the external preparation for skin of the present invention> The antifungal external preparation obtained in Example 14 and the antifungal external preparation obtained in Comparative Example 12 were tested for bactericidal action. . That is, 1 g of each of the above antifungal external preparations was taken, and 2 × 10 5 conidia of Trichophyton mentaglophyte were planted in each of them.
After 4 days, the state of survival of the conidia was determined by staining.
【００７７】結果は、実施例１４の抗真菌皮膚外用剤中
に生存している菌体はほとんど認められなかったが、比
較例１２の抗真菌皮膚外用剤中では菌は僅かに生存して
いた。この結果より、実施例１４の抗真菌皮膚外用剤に
おいては、比較例１２の抗真菌皮膚外用剤に比べて、抗
真菌剤であるビフォナゾールを細胞膜を通して浸潤させ
る作用に優れることがわかる。このことから、実施例で
得られた皮膚外用剤は、乳化組成物が本来的に有する浸
透作用の機能を損なっていないと言える。As a result, few surviving cells were observed in the antifungal external preparation of Example 14, but a small amount of bacteria were alive in the antifungal external preparation of Comparative Example 12. . From these results, it can be seen that the antifungal external preparation of Example 14 is superior to the antifungal external preparation of Comparative Example 12 in the action of infiltrating the antifungal agent bifonazole through the cell membrane. From this, it can be said that the external preparations for skin obtained in Examples do not impair the function of the penetrating action originally possessed by the emulsified composition.
【００７８】[0078]
【発明の効果】本発明の乳化組成物においては、シュー
ドモナス・エロディアが産生するグルコース、グルクロ
ン酸及びラムノースを構成糖とする多糖類と、揮発性油
剤と、カルボニル基を有する水不溶性高分子粉末とを含
有することで、組成物に優れた使用感を付与することが
できるとともに、乳化組成物が本来的に有する洗浄作用
や浸透作用等の機能を損なうことなく、また、乳化剤形
に支障を与えることなく、組成物中の界面活性剤の含有
量を減量することが可能である。このようにして乳化組
成物中の界面活性剤の配合量を少なくすることが可能と
なれば、化粧料においては界面活性剤に由来する化粧崩
れや安全性の低下などの問題を、また、皮膚外用医薬品
においては界面活性剤に由来する皮膚内貯留性の損失、
安全性の低下等の問題を、それぞれの乳化組成物の有す
る本来的な機能を低下させることなく有効に解決するこ
とが可能となる。INDUSTRIAL APPLICABILITY In the emulsified composition of the present invention, a polysaccharide produced by Pseudomonas erodia containing glucose, glucuronic acid and rhamnose as a constituent sugar, a volatile oil agent, and a water-insoluble polymer powder having a carbonyl group. By containing, it is possible to give the composition an excellent feeling of use, without impairing the functions such as the cleaning action and the penetration action originally possessed by the emulsified composition, and also giving an obstacle to the emulsifier form. Without, it is possible to reduce the content of surfactants in the composition. If it becomes possible to reduce the content of the surfactant in the emulsified composition in this way, in cosmetics, problems such as makeup deterioration and reduced safety due to the surfactant may be caused. Loss of skin retention due to surfactants in external medicines,
It is possible to effectively solve problems such as a decrease in safety without deteriorating the intrinsic function of each emulsion composition.
───────────────────────────────────────────────────── フロントページの続き (51)Int.Cl.6 識別記号 庁内整理番号 ＦＩ 技術表示箇所 // Ｃ０８Ｂ 37/00 Ｃ０８Ｂ 37/00 Ｐ ─────────────────────────────────────────────────── ─── Continuation of the front page (51) Int.Cl. 6 Identification code Office reference number FI technical display location // C08B 37/00 C08B 37/00 P
Claims (9)
するグルコース、グルクロン酸及びラムノースを構成糖
とする多糖類と、(2)揮発性油剤と、(3)カルボニル基を
有する水不溶性高分子粉末と、を含有する乳化組成物。1. (1) A polysaccharide produced by Pseudomonas erodia and having glucose, glucuronic acid and rhamnose as a constituent sugar, (2) a volatile oil agent, and (3) a water-insoluble polymer powder having a carbonyl group. An emulsified composition containing a.
３）−β−D−グルコース（１→４）−β−D−グルクロ
ン酸（１→４）−β−D−グルコース（１→４）−α−L
−ラムノース（１→］を繰り返し単位とする多糖類であ
る請求項１記載の乳化組成物。 【化１】 （但し、ｎは整数を表す。）2. A polysaccharide is represented by the general formula (I) [→
3) -β-D-glucose (1 → 4) -β-D-glucuronic acid (1 → 4) -β-D-glucose (1 → 4) -α-L
An emulsified composition according to claim 1, which is a polysaccharide having rhamnose (1 →) as a repeating unit. (However, n represents an integer.)
００℃未満である請求項１又は２記載の乳化組成物。3. The boiling point of the volatile oil agent at atmospheric pressure is 2.
The emulsified composition according to claim 1 or 2, which has a temperature of less than 00 ° C.
ストークスのジメチルポリシロキサン、３〜６量体の環
状ジメチルポリシロキサン、炭素数２０未満の分岐の炭
化水素及び総炭素数１２未満のエステルから選ばれる１
種又は２種以上である請求項１〜３の何れか一項に記載
の乳化組成物。4. The volatile oil agent is a dimethylpolysiloxane having a viscosity of 0.1 to 10 centistokes, a cyclic dimethylpolysiloxane having a trimer of 3 to 6, a branched hydrocarbon having less than 20 carbon atoms and a total hydrocarbon having less than 12 carbon atoms. 1 selected from ester
The emulsion composition according to any one of claims 1 to 3, which is one kind or two or more kinds.
末が、水不溶性多糖類粉末、水不溶性タンパク質粉末、
ポリアミド粉末、アクリル樹脂粉末から選ばれる１種又
は２種以上である請求項１〜４の何れか一項に記載の乳
化組成物。5. A water-insoluble polymer powder having a carbonyl group, a water-insoluble polysaccharide powder, a water-insoluble protein powder,
The emulsified composition according to any one of claims 1 to 4, which is one kind or two or more kinds selected from polyamide powder and acrylic resin powder.
末が、セルロース粉末、シルクパウダー、牛皮革粉末か
ら選ばれる１種又は２種以上である請求項５記載の乳化
組成物。6. The emulsion composition according to claim 5, wherein the water-insoluble polymer powder having a carbonyl group is one or more selected from cellulose powder, silk powder and cowhide powder.
０．１〜５重量％であり、揮発性油剤の含有量が組成物
全量に対して１〜９０重量％であり、カルボニル基を有
する水不溶性高分子粉末の含有量が組成物全量に対して
０．１〜２０重量％である請求項１〜６の何れか一項に
記載の乳化組成物。7. The content of the polysaccharide is 0.1 to 5% by weight with respect to the total amount of the composition, and the content of the volatile oil agent is 1 to 90% by weight with respect to the total amount of the composition. The emulsified composition according to any one of claims 1 to 6, wherein the content of the water-insoluble polymer powder having a content of 0.1 to 20% by weight based on the total amount of the composition.
に記載の乳化組成物。8. The emulsified composition according to any one of claims 1 to 7, which is a cosmetic.
れか一項に記載の乳化組成物。9. The emulsion composition according to any one of claims 1 to 7, which is a skin external drug.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP06656396A JP3294758B2 (en) | 1996-03-22 | 1996-03-22 | Gel emulsion composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP06656396A JP3294758B2 (en) | 1996-03-22 | 1996-03-22 | Gel emulsion composition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH09255560A true JPH09255560A (en) | 1997-09-30 |
| JP3294758B2 JP3294758B2 (en) | 2002-06-24 |
Family
ID=13319548
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP06656396A Expired - Fee Related JP3294758B2 (en) | 1996-03-22 | 1996-03-22 | Gel emulsion composition |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP3294758B2 (en) |
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6960339B1 (en) | 1999-07-15 | 2005-11-01 | L'oreal S.A. | Compositions structured with at least one polymer and methods of using the same |
| US7008629B2 (en) | 2002-07-22 | 2006-03-07 | L'ORéAL S.A. | Compositions comprising at least one heteropolymer and fibers, and methods of using the same |
| US7008619B2 (en) | 2001-10-05 | 2006-03-07 | L'oreal S.A. | Methods of use and of making a mascara comprising at least one coloring agent and at least one polyamide polymer chosen from the ethylenediamine/stearyl dimer tallate copolymer |
| US7011823B2 (en) | 2000-12-12 | 2006-03-14 | L'oreal S.A. | Method of making a mascara composition comprising a polyamide polymer and at least one inert filler |
| US7025953B2 (en) | 2001-01-17 | 2006-04-11 | L'oreal S.A. | Nail polish composition comprising a polymer |
| US7030985B2 (en) | 2000-12-12 | 2006-04-18 | L'oréal | Colored transparent or translucent cosmetic composition |
| US7052681B2 (en) | 2001-01-17 | 2006-05-30 | L'ORéAL S.A. | Cosmetic composition containing a polymer and a fluoro oil |
| US7144582B1 (en) | 1999-07-15 | 2006-12-05 | L'ORéAL S.A. | Compositions structured with at least one polymer and methods of using the same |
| US7276547B2 (en) | 2000-12-12 | 2007-10-02 | L'oreal S.A. | Compositions comprising heteropolymers and at least one oil-soluble polymers chosen from alkyl celluloses and alkylated guar gums |
| US7314612B2 (en) | 2000-12-12 | 2008-01-01 | L'oreal S.A. | Cosmetic compositions containing at least one heteropolymer and at least one gelling agent and methods of using the same |
| US7351418B2 (en) | 2000-12-12 | 2008-04-01 | L'oreal S.A. | Cosmetic composition comprising a polymer blend |
| US7410636B2 (en) | 2000-12-12 | 2008-08-12 | L'oreal S.A. | Cosmetic composition comprising a polymer and fibres |
| US7491749B2 (en) | 2000-12-12 | 2009-02-17 | L'oreal | At least one polyamide polymer in a cosmetic composition comprising at least one solid substance having a melting point of 45 degrees C. or greater |
-
1996
- 1996-03-22 JP JP06656396A patent/JP3294758B2/en not_active Expired - Fee Related
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7144582B1 (en) | 1999-07-15 | 2006-12-05 | L'ORéAL S.A. | Compositions structured with at least one polymer and methods of using the same |
| US6960339B1 (en) | 1999-07-15 | 2005-11-01 | L'oreal S.A. | Compositions structured with at least one polymer and methods of using the same |
| US7314612B2 (en) | 2000-12-12 | 2008-01-01 | L'oreal S.A. | Cosmetic compositions containing at least one heteropolymer and at least one gelling agent and methods of using the same |
| US7011823B2 (en) | 2000-12-12 | 2006-03-14 | L'oreal S.A. | Method of making a mascara composition comprising a polyamide polymer and at least one inert filler |
| US7030985B2 (en) | 2000-12-12 | 2006-04-18 | L'oréal | Colored transparent or translucent cosmetic composition |
| US7276547B2 (en) | 2000-12-12 | 2007-10-02 | L'oreal S.A. | Compositions comprising heteropolymers and at least one oil-soluble polymers chosen from alkyl celluloses and alkylated guar gums |
| US7351418B2 (en) | 2000-12-12 | 2008-04-01 | L'oreal S.A. | Cosmetic composition comprising a polymer blend |
| US7410636B2 (en) | 2000-12-12 | 2008-08-12 | L'oreal S.A. | Cosmetic composition comprising a polymer and fibres |
| US7491749B2 (en) | 2000-12-12 | 2009-02-17 | L'oreal | At least one polyamide polymer in a cosmetic composition comprising at least one solid substance having a melting point of 45 degrees C. or greater |
| US7025953B2 (en) | 2001-01-17 | 2006-04-11 | L'oreal S.A. | Nail polish composition comprising a polymer |
| US7052681B2 (en) | 2001-01-17 | 2006-05-30 | L'ORéAL S.A. | Cosmetic composition containing a polymer and a fluoro oil |
| US7008619B2 (en) | 2001-10-05 | 2006-03-07 | L'oreal S.A. | Methods of use and of making a mascara comprising at least one coloring agent and at least one polyamide polymer chosen from the ethylenediamine/stearyl dimer tallate copolymer |
| US7008629B2 (en) | 2002-07-22 | 2006-03-07 | L'ORéAL S.A. | Compositions comprising at least one heteropolymer and fibers, and methods of using the same |
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