JPH0875752A - Reagent stirring method - Google Patents

Abstract

(57) [Summary] [Purpose] Rotate and vertically move the stirrer that stirs the reagent, and detect the liquid surface state of the stirred reagent.
To control the rotation of a rotating stirrer so that a reagent can be made to have a uniform concentration in a short time. [Structure] A stirrer 3 having a rotating mechanism 5 and an up-and-down mechanism 4
Is immersed in the container 1 of the reagent solution 2, and the stirrer 3 and the up-and-down mechanism 4 are simultaneously operated by the operation mechanism 6 to stir the reagent solution 2. Further, the operation control unit 6 controls the rotation speed of the stirrer 3 to stir the reagent liquid 2, and at the same time, the liquid surface state of the reagent liquid 2 is monitored by the liquid surface state detection unit, and the detection signal is sent to the detection signal processing unit. By supplying, the operation control unit 6 outputs a control signal to the rotating mechanism 5.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a reagent stirring method for an automatic analyzer used in medical equipment.

[0002]

2. Description of the Related Art Conventionally, a precipitating liquid reagent for an analyzer is
Since it is necessary to make the concentration uniform during the analysis, the reagent containing the precipitating substance is manually stirred to make the concentration of the reagent uniform and then used for the analysis.

Although there is an example of stirring a reagent as in Japanese Patent Laid-Open No. 5-322721, the method of stirring the reagent by simultaneously rotating and rotating the stirrer, which is the object of the present invention, is described. I haven't touched it.

[0004]

In the conventional method, the reagent concentration was made uniform by manually stirring the reagent. Therefore, due to the variation of the stirring time, the quantitative uniformity of the concentration could not be obtained, which affected the analysis results. Further, the generation of bubbles on the liquid surface of the reagent due to excessive stirring has a problem of affecting the dispensing means when dispensing the reagent. Furthermore, since the amount of work is increased, it is considered to be a cause of impeding the time reduction.

An object of the present invention is to provide a stirring method capable of uniformly stirring the concentration of a reagent solution containing a sedimentable substance in a short time.

[0006]

[Means for Solving the Problems] In a reagent container,
Immerse a stirrer with rotation and up-and-down mechanism in the reagent,
The stirrer is rotated and moved up and down to stir the reagent. Further, by controlling the rotation speed of the stirrer stirring the reagent, and simultaneously monitoring the liquid surface state of the reagent stirred in the container and supplying the information to the rotation speed controlling means, Can solve problems.

[0007]

With the above mechanism and means, the concentration of the reagent can be made uniform in a short time. In addition, the reproducibility of the measurement result is ensured with the constant concentration of the reagent.

Furthermore, it becomes possible to prevent the generation of bubbles, which is a problem during reagent dispensing, and it is possible to accurately detect the liquid surface of the reagent during reagent dispensing.

[0009]

Embodiments of the present invention will be described below with reference to the drawings.

A container 1 for containing a reagent solution 2 containing a sedimentable substance, a rotating mechanism 5 for rotating a stirrer 3, a vertical mechanism 4 for vertically moving a stirrer 3 and a rotating mechanism 5, a rotating mechanism 5, and a vertical mechanism 4 FIG. 1 shows a first embodiment configured by an operation control unit 6 for controlling the operations of and. An agitator 3 having a rotating mechanism 5 and an up-and-down mechanism 4 is immersed in the reagent solution 2 up to the vicinity of the bottom of the container 1 by controlling the operation controller 6, and the agitator 3 is rotated by the rotating mechanism 5 to agitate the reagent solution 2. . Further, the operation control unit 6 controls the up-and-down mechanism 4 for vertically moving the agitator 3 rotating by the rotating mechanism 5 from the container bottom to the vicinity of the liquid surface. These operations are performed by the operation control unit 6.
By simultaneously controlling and stirring the reagent solution 2, it becomes possible to make the dispersed concentration of the sedimentable substance in the reagent solution 2 uniform in a short time.

In addition, a second embodiment constructed by adding a liquid level state detecting section 7 for detecting a liquid level state and a detection signal processing section 8 for processing a liquid level state detection signal to the configuration of FIG. Shown in. Further, FIG. 3 shows a rotation speed control state of the rotation mechanism 5. Rotation mechanism 5 for rotating the stirrer 3 in the container 1
The operation control unit 6 stirs the reagent solution 2 while controlling the rotation speed of the stirrer 3 as shown in FIG. Further, the liquid surface state detection unit 7 monitors the liquid surface state of the reagent liquid 2 stirred by the stirrer 3. The liquid surface state detection unit 7 that detects the state of the liquid surface supplies the detection signal 9 immediately before the bubble of the reagent liquid 2 is generated to the detection signal processing unit 8 and outputs the control signal to the operation control unit 6. Thereby, the rotation speed of the rotation mechanism 5 is controlled to a constant rotation speed as shown in FIG. As a result, the reagent solution 2
Can make the concentration of the reagent solution 2 uniform in a short time. Further, since the reagent solution 2 is stirred by the stirrer 3 at the optimum rotation speed, it becomes possible to prevent the generation of bubbles.

Further, a third embodiment will be described in the configuration of FIG. The rotation speed of the rotating mechanism 5 for rotating the stirrer 3 is set so as to rotate at high speed when the stirrer 3 is moved to the vicinity of the bottom of the container 1 by the vertical movement mechanism 4, and to rotate at low speed when it is moved near the liquid surface. The concentration of the reagent solution 2 can be made uniform in a short time by controlling and stirring by the operation control unit 6.

[0013]

According to the present invention, the concentration of the reagent can be made uniform in a short time by the method described above. Further, since it becomes possible to prevent the generation of bubbles, it is possible to contribute to the improvement of the processing speed of the apparatus and the reduction of the liquid level erroneous detection.

[Brief description of drawings]

FIG. 1 is a schematic diagram showing a reagent stirring mechanism according to a first embodiment of the present invention.

FIG. 2 is a schematic diagram showing a reagent stirring mechanism according to second and third embodiments of the present invention.

FIG. 3 is a graph schematically showing a change in rotation speed of a rotation mechanism.

[Explanation of symbols]

1 ... Container, 2 ... Reagent liquid, 3 ... Stirrer, 4 ... Vertical mechanism, 5
... Rotation mechanism, 6 ... Operation control section, 7 ... Liquid level state detection section, 8
... detection signal processing unit, 9 ... detection signal.

─────────────────────────────────────────────────── ─── Continuation of the front page (51) Int.Cl. ⁶ Identification code Office reference number FI technical display area // G01N 1/36

Claims (3)

[Claims] 1. A method for stirring a reagent for an analyzer, comprising means for controlling the rotating operation and rotation speed of the stirrer, and means for vertically moving the stirrer, wherein the two means are simultaneously operated. A method for stirring a reagent, which comprises operating and stirring. 2. The reagent stirring method according to claim 1, further comprising means for detecting the liquid level state of the reagent or the density of the reagent,
A reagent stirring method characterized in that the number of rotations of the stirrer with respect to the reagent is found by detecting the liquid level state or the density of the reagent stirred by this means. 3. The reagent agitation method according to claim 2, wherein the rotation speed and the up and down movement of the agitator for agitating the reagent by rotating and vertically moving the reagent enable high speed operation near the bottom of the container. , A reagent stirring method characterized in that the reagent is stirred so as to operate at a low speed near the liquid surface.