JPH08325111A - Agro-horticultural fungicide - Google Patents

Abstract

(57) [Summary] [Object] An object of the present invention is to provide a fungicide for agricultural and horticultural use, which has a high fungicidal activity, a high fungicidal spectrum, and is free from the risk of emergence of resistant bacteria. [Structure] The agricultural and horticultural germicide of the present invention comprises a copper salt and 2-cyano-N-[(ethylamino) carbonyl] -2- (methoxyimino) acetamide as active ingredients.

Description

Detailed Description of the Invention

[0001]

FIELD OF THE INVENTION The present invention relates to an agricultural and horticultural fungicide.

[0002]

2. Description of the Related Art Disease damage to agricultural crops such as rice, vegetables, fruit trees and flowers is very serious and causes a decrease in the amount of crops and a deterioration in quality, which is a serious problem. Therefore, in order to control these diseases, various agricultural and horticultural fungicides have been conventionally developed and used. For example, typical examples thereof include benzimidazole fungicides such as methyl-1-butylcarbamoyl-2-benzimidazole carbamate (generic name: benomyl), 1- (4-chlorophenoxy) -3,3-dimethyl-1. Ersosterol biosynthesis-inhibiting fungicides such as-(1,2,4-triazol-1-yl) -2-butanone (generic name: triadimefon), bis (dimethylthiocarbamoyl) disulfide (generic name:
Dithiocarbamate fungicides such as thiuram) and oxolinic acid. However, with these conventional bactericides, drug-resistant bacteria appear due to continuous use, and reduction of the bactericidal effect is unavoidable.

2-Cyano-N-[(ethylamino) carbonyl] -2- (methoxyimino) acetamide, which is known by the general name cimoxanil, is also used as an agent for controlling epidemics such as grapes and potatoes, but has a narrow bactericidal spectrum. However, it has a drawback that it does not have sufficient bactericidal activity and that a resistant bacterium may appear due to frequent use. Therefore, development of a new bactericidal agent which does not have these drawbacks is desired.

On the other hand, a copper bactericide containing a copper salt (copper agent) is a well-known bactericide, and for example, a bactericide containing cupric hydroxide, copper nonylphenyl sulfonate, etc. as an active ingredient is widely used. ing. The bactericide has a broad bactericidal spectrum,
It is known that the resistant bacterium may not appear even by heavy use, but the bactericidal effect is somewhat weak, and it is essential to use a high concentration in order to obtain a sufficient effect. Therefore, there is a concern that the chemical damage to crops and the adverse effect on the environment may occur.

[0005]

DISCLOSURE OF INVENTION Problems to be Solved by the Invention The present inventor has conducted research to obtain a bactericidal agent having a high bactericidal activity, a high bactericidal spectrum, and no risk of emergence of resistant bacteria, and is known as a food additive. A highly safe copper salt of aldonic acid such as cupric gluconate is a compound that meets the object of the present invention, and has a higher bactericidal activity than conventional copper agents, so that the amount used is small, and therefore They found that the phytotoxicity to crops was very low. The copper salt of aldonic acid is
As described above, although it is a very excellent bactericide, it is the current situation that development of a bactericide having higher bactericidal activity and less phytotoxicity is desired.

[0006]

Means for Solving the Problems As a result of intensive studies to solve the above-mentioned problems, the present inventor has found that the combination of a copper agent and a specific known fungicide, cimoxanil, results in an unexpected synergistic effect. It has a broad spectrum of bactericidal effects and exhibits outstanding bactericidal activity not only against general bacteria and filamentous fungi but also against drug-resistant bacteria. It has been found that an agricultural and horticultural fungicide can be obtained which is effective, has no phytotoxicity, and has no adverse effect on the environment. The present invention has been completed based on these findings.

That is, the present invention relates to a copper salt and 2-cyano-N-
The present invention relates to an agricultural and horticultural germicide containing [(ethylamino) carbonyl] -2- (methoxyimino) acetamide (simoxanil) as an active ingredient.

As the copper agent used in the present invention,
For example, inorganic copper used as a bactericide, copper terephthalate, copper nonylphenyl sulfonate, copper oxyquinoline, copper salts of aldonic acid and the like can be widely mentioned,
Preferably copper nonylphenyl sulfonate and copper salts of aldonic acid are used. The copper salt of aldonic acid is a copper salt of a compound in which the aldehyde group of a monosaccharide having an aldehyde group is oxidized to be a carboxyl group. Examples of monosaccharides having an aldehyde group include aldotrioses such as D-glyceraldehyde, aldetetroses such as D-erythrose, D-ribose, D-xylose and L.
-Aldopentoses such as arabinose, and aldohexoses such as D-glucose, D-galactose and D-mannose. Of the aldonic acid copper salts, cupric gluconate is preferred. Since cupric gluconate has a high bactericidal effect and is known as a food additive, it is extremely safe for the environment.

In the present invention, the use ratio of the copper salt and the cimoxanil is not particularly limited, but the copper salt in the disinfectant of the present invention is usually 0.5 to 80% by weight, preferably 5 to 60. % By weight, and cimoxanil is usually 0.5-
It is preferable to appropriately select the use ratio of both components so that the content is 50% by weight, preferably 5 to 40% by weight.

The bactericide of the present invention may be prepared by using a suitable carrier, surfactant, etc., as necessary, similarly to known bactericides, for example, sprays, wettable powders, emulsions, powders, granules and flowables. It can be prepared and used in a general formulation form such as an agent. Known carriers can be used, for example, clay, kaolin, bentonite, talc, acid clay, diatomaceous earth, calcium carbonate, potassium sulfate, potassium chloride, potassium nitrate, potassium dihydrogen phosphate, sodium sulfate,
Nitrocellulose, starch, gum arabic, carbon dioxide, freon, benzene, kerosene, alcohol, acetone, xylene, methylnaphthalene, cyclohexane,
Examples thereof include animal and plant fatty acid esters. Known surfactants can be used, for example, lecithin, sucrose fatty acid ester, sorbitan fatty acid ester, monoglyceride, polypropylene glycol fatty acid ester, soap, sulfuric acid ester of higher alcohol,
Examples thereof include alkyl sulfonate, quaternary ammonium salt, polyalkylene oxide, sodium lignin sulfonate, sodium alkylbenzene sulfonate, sodium dinaphthylmethane sulfonate, sodium lauryl alcohol sulfate, and polyoxyethylene alkylaryl ether.

In applying the fungicide of the present invention to disease control of crops, well-known methods can be widely adopted, but generally, methods such as seed dipping, foliar application and soil irrigation are used. When applied to rice, potatoes, etc., rice paddies and potatoes are soaked,
For application to vegetables and fruit trees, foliage spraying is applied, and for soil diseases of vegetables and flowers, soil irrigation is applied.

In applying the fungicide of the present invention to crops, the composition may be used as it is or diluted with water. The concentration of the active ingredient depends on the type of target disease,
It is appropriately selected from a wide range depending on the degree of growth of the target crop, the treatment method, the weather, etc., but preferably about 10-500 ppm of cimoxanil and 200-5000 pp of copper agent.
It may be about m (copper concentration is about 25 to 700 ppm).

The target crops and target diseases of the fungicide of the present invention are not particularly limited. Specific examples of the target crops include rice, vegetables, fruit trees, and flowers. Specific examples of the target disease include, for example, bacterial diseases, powdery mildew, downy mildew, epidemics and other filamentous fungi. The fungicide of the present invention is particularly effective against diseases of flower crops.

Diseases of various crops are as follows.

Rice: Bacterial blight, bacterial blight, brown streak, sapling, sesame leaf blight, blast cucumber: spot bacterial disease, downy mildew, powdery mildew tomato: plague, spot bacterial Disease, scabbing lettuce: spotted bacterial disease, soft rot, rot, downy mildew spinach: downy mildew onion, radish, Chinese cabbage: soft rot, black rot, downy mildew pepper: spotted bacterial disease, epidemic watermelon: epidemic strawberry : Powdery mildew Melon: Bacterial spot disease, downy mildew, powdery mildew Cabbage: Black rot, soft rot, downy mildew Carrot: Black leaf blight Potato: Plague, scab Citrus: Canker, yellow spot , Black spot disease Grapes: Downy mildew, rust, powdery mildew Kiwifruit: Bacterial bacterial rot, causal illness Cherry peach: Pore illness Plum: Kaiyou peach peach: Porous bacillus Tea: Red burn, anthracnose, net rice blast Disease, rice blast Hop: Mildew Rose: Powdery mildew.

[0016]

EFFECTS OF THE INVENTION The fungicide of the present invention exerts a synergistic effect by the combined use of two kinds of active ingredients, a copper salt and simoxanil. Not only bacteria but also drug-resistant bacteria exhibit an excellent bactericidal effect. Further, the use of the fungicide of the present invention makes it possible to reduce the amount of chemicals to be treated, so that there is no fear of phytotoxicity to crops or adverse effects on the environment.

[0017]

EXAMPLES The present invention will be specifically described below with reference to formulation examples and test examples. Hereinafter, "%" means "% by weight".

Formulation Example 1 (Preparation of wettable powder) 52 g of copper nonylphenyl sulfonate (60% content), 16 g of cimoxanil, 24 g of clay and 8 g of a surfactant (trade name: Agrisol W150, manufactured by Kao Corporation) are sufficient. And dried. This mixture is then well ground,
Copper nonylphenyl sulfonate 30% and Cimoxanil 1
A fungicide of the invention in the form of a wettable powder containing 5% was obtained.

Formulation Example 2 (Preparation of Wettable Powder) 32 g of copper gluconate, 16 g of cimoxanil, 51 g of sodium sulfate and a surfactant (trade name: Lebenol WZ,
1 g of Kao Corporation was thoroughly mixed. The mixture is then ground well, copper gluconate 30% and cimoxanil 1
A fungicide according to the invention in the form of a wettable powder containing 5% was obtained.

Test Example 1 (Rice Seedling Bacterial Disease Control Test) A 100 ml beaker was charged with the wettable powder prepared in Formulation Examples 1 and 2 and diluted 500 times with water to give 600 ppm of a copper agent.
A solution containing 300 ppm of cimoxanil was prepared, and 10 g of rice paddy before seeding contaminated with rice seedling wilting disease was soaked for 24 hours. The treated rice grain was soaked at 20 ° C. for 3 days, germinated at 32 ° C. for 1 day, and then seeded in a 12 × 12 cm plastic case. This was kept at a temperature of 32 ° C. for 2 days, then managed in a greenhouse, and after 2 weeks, the number of diseased seedlings was counted and the control value was calculated by the following formula.

[0021]

[Equation 1]

For comparison, copper nonylphenyl sulfonate, copper gluconate, simoxanil, and a commercially available fungicide (coside bordeaux: cupric hydroxide, stanna: oxolic acid) were also treated in the same manner. The results are shown in Table 1.

[0023]

[Table 1]

Test Example 2 (Cucumber Bacterial Spot Bacterial Disease Control Test) The wettable powders of Formulation Examples 1 and 2 were diluted 1000 times with water to prepare a solution containing 300 ppm of copper agent and 150 ppm of cimoxanil. 5 ml of this was sprayed on a cucumber seedling at the 1-leaf stage of a true leaf planted in a black vinyl pot, and after 5 hours, a bacterial disease of spot of cucumber was spray-inoculated. After being kept under high humidity at 25 ° C for 7 hours, the disease degree of the seedlings was investigated and the control value was calculated by the following formula.

[0025]

[Equation 2]

For comparison, copper nonylphenyl sulfonate, copper gluconate, simoxanil and a commercially available bactericide (coside bordeaux: cupric hydroxide) were also treated in the same manner. Table 2 shows the results.

[0027]

[Table 2]

Test Example 3 (Tomato epidemic control test) The wettable powders of Formulation Examples 1 and 2 were diluted 1000 times with water to prepare a solution containing 300 ppm of copper agent and 150 ppm of cimoxanil. 5 ml of this was sprayed on tomato seedlings at the 4-leaf stage of true leaves planted in a black vinyl pot, and after 5 hours, spores of Phytophthora infestans were spray-inoculated. After being kept under high humidity at 25 ° C. for 7 hours, the disease degree of the seedlings was investigated, and the control value was calculated in the same manner as in Test Example 2.

For comparison, copper nonylphenyl sulfonate, copper gluconate, simoxanil and a commercially available bactericide (coside bordeaux: cupric hydroxide) were also treated in the same manner. The results are shown in Table 3.

[0030]

[Table 3]

Test Example 4 (Cucumber Powdery Mildew Control Test) The wettable powders of Formulation Examples 1 and 2 were diluted 1000 times with water to prepare a solution containing 300 ppm of copper agent and 150 ppm of cimoxanil. 5 ml of this was sprayed on a cucumber seedling at the 1st leaf stage of a true leaf planted in a black vinyl pot, and after 5 hours, spores of bentore-resistant cucumber powdery mildew were spray-inoculated. After being kept in the greenhouse for 10 days, the degree of disease onset was investigated, and the control value was calculated in the same manner as in Test Example 2.

For comparison, copper nonylphenyl sulfonate, copper gluconate, simoxanil, and a commercially available bactericide (coside bordeaux: cupric hydroxide, bentrate: benomyl) were also treated in the same manner. The results are shown in Table 4.

[0033]

[Table 4]

 ─────────────────────────────────────────────────── ─── Continuation of the front page (72) Inventor Tomomi Komura, 615, Satoura-cho, Satoura-cho, Naruto-shi, Tokushima Prefecture, Naruto Laboratory, Otsuka Chemical Co., Ltd. (72) Kazumi Sagayama, 615, Satoura-cho, Satoura-cho, Naruto-shi, Tokushima Prefecture Otsuka Chemical Co., Ltd. Naruto Laboratory

Claims (4)

[Claims] 1. A fungicide for agriculture and horticulture, which comprises a copper salt and 2-cyano-N-[(ethylamino) carbonyl] -2- (methoxyimino) acetamide as active ingredients. 2. The copper salt is a copper salt of aldonic acid.
Agricultural and horticultural germicide described in. 3. The fungicide for agricultural and horticultural use according to claim 2, wherein the copper salt of aldonic acid is cupric gluconate. 4. The agricultural and horticultural fungicide according to claim 1, wherein the copper salt is copper nonylphenyl sulfonate.