JPH08262034A - Autoanalyzer - Google Patents

Abstract

PURPOSE: To provide an autoanalyzer which does not have a bad influence on the acquisition of analytical data on a sample which his already been set when a sample is to be set. CONSTITUTION: A sample which has been put into a sample container 1 is set in a sample setting position on a sample disk 2. When the sample is to be set, the sample setting position in which the sample is to be set is displayed automatically on a CRT screen. As a result, it is sufficient to set the sample in the sample setting position which has been instructed. The sample which has been set is dispensed into a reaction container together with a reagent inside a reagent container 8 so as to be reacted. The sampe which has been reacted is measured by a luminous intensity system 16.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an automatic analyzer, and more particularly to an automatic analyzer suitable for setting and analyzing a plurality of specimens one after another.

[0002]

2. Description of the Related Art In an automatic analyzer, many sample set positions are provided on a sample disk, samples are sequentially set at the set positions, and the samples are sequentially sampled and analyzed. In this case, the operator inputs the sample set position where the sample is set to the computer memory every time when the sample is set at an empty sample set position for use as analysis ID information of the sample after setting. Is common.

[0003]

However, in such a method, an input error is likely to occur and the operator may not notice the input error. For example, if a sample set position number that has already been input is mistakenly input as the sample set position number of the sample that has just been set, it will be impossible to obtain analysis data for the sample with the already input sample set position number. A serious situation will occur.

The present invention has been made in view of such circumstances, and an object thereof is to provide an automatic analyzer which does not adversely affect acquisition of analysis data of a sample already set when the sample is set. To do.

[0005]

Means for solving the problems of the present invention are as follows.

1. An automatic analyzer, which comprises a sample holder having a plurality of sample set positions and setting and holding samples at those sample set positions, and means for sampling and analyzing the set samples An automatic analyzer comprising: when setting the sample to the plurality of sample set positions, among the plurality of sample set positions, an empty sample set position to which each of the samples should be set Is provided prior to each set of the specimens (claim 1).

2. In the automatic analyzer described in the problem solving means 1, when the designated sample set position has a plurality of vacant sample set positions, the waiting time until sampling is shortest. It is a sample set position (Claim 2).

3. The automatic analyzer of the problem solving means 1 or 2, wherein the sample set position indicating means has a display screen, and an empty sample set to which each of the samples is to be set among the plurality of sample set positions The position is displayed on the display screen (claim 3).

4. An automatic analyzer, which comprises a sample holder having a plurality of sample set positions and setting and holding samples at those sample set positions, and means for sampling and analyzing the set samples An automatic analyzer comprising: when setting the sample to the plurality of sample set positions, among the plurality of sample set positions, an empty sample set position to which each of the samples should be set Is provided prior to each set of the sample, and means for selecting an analysis item of the set sample (claim 4).

5. In the automatic analyzer of the problem solving means 4, the designated sample set position is the sample set position where the waiting time until sampling is shortest among a plurality of vacant sample set positions. (Claim 5).

6. The automatic analyzer of the problem solving means 4 or 5, wherein the sample set position indicating means has a display screen, and an empty sample set to which each of the samples is to be set among the plurality of sample set positions The position is displayed on the display screen (claim 6).

7. An automatic analyzer, which has a plurality of sample set positions, and a sample holding unit that sets and holds the samples at those sample set positions, and a sample set at the sample set position as a first sample Means for driving the sample holding means so as to move it to a position;
Inhaling the specimen that has moved to the position of
An automatic analyzer comprising means for discharging at the position of, and means for analyzing the discharged sample,
When setting the specimens to the plurality of specimen set positions, an empty specimen set position in which the respective specimens should be set among the plurality of specimen set positions is displayed prior to each set of the specimens. And a means for selecting an analysis item of the sample to be set (claim 7).

8. The automatic analyzer described in Problem Solving Means 7 is provided with means for displaying the operation stop of the sample holding means and the sample inhaling and discharging means during the operation stop time, and the display is issued. It is characterized in that the sample can be set during the operation (claim 8).

9. The automatic analyzer of the problem solving means 8 is characterized in that the operation stop display means is a luminous body, and the luminous body is arranged in the vicinity of the sample holding means (claim 9).

10. In the automatic analyzer according to any one of the problem solving means 7 to 9, when the designated sample set position has a plurality of empty sample set positions, the waiting time until the sample is inhaled is the shortest. It is characterized in that it is at a certain sample set position (claim 1
0).

[0016]

In the present invention, when a sample is set at a plurality of sample setting positions, among the plurality of sample setting positions,
An empty sample set position where each of the samples should be set is indicated prior to the setting of each of the samples. Therefore, when setting the sample, the operator is informed of the sample setting position at which the sample should be set, so the operator only has to set the sample at the specified sample setting position. become,
Therefore, when the sample is set, there is no adverse effect on the acquisition of the analysis data of the already set sample.

The designated sample set position is the sample set position where the waiting time until sampling is shortest among a plurality of vacant sample set positions. Therefore, the analysis waiting time can be shortened, and the analysis time as a whole can be shortened.

Further, a sample holding means having a plurality of sample set positions and setting and holding the samples at those sample set positions, and moving the sample set at the sample set position to the first position A means for driving the means for holding the sample, a means for inhaling the sample moved to the first position and discharging the inhaled sample at the second position, and a means for analyzing the discharged sample In the automatic analyzer comprising, when setting the sample to the plurality of sample set positions, among the plurality of sample set positions, the empty sample set position to set each of the samples A means for displaying prior to each set of samples, and means for displaying the stoppage of the sample holding means and the sample inhaling and discharging means during the stoppage time. , It is adapted to set the specimen while the display is issued. Therefore, according to this, in addition to the fact that when the sample is set, it does not adversely affect the analysis data acquisition of the sample that has already been set, it is safe even for laymen without risking the sample. Can be set to.

[0019]

FIG. 1 shows an embodiment of the present invention. In the figure, 1 is a sample container containing a sample to be analyzed, 2
Is a sample disc for mounting and holding the sample container 1,
A bar code reader 3 reads a sample identifying bar code 4 of a bar code label attached to the sample container 1.

The sample in the sample container 1 is the reaction disk 5
It is dispensed into the reaction container 6 of. This dispensing is performed by the sample dispensing device 7. Reference numeral 8 is a reagent container containing a reagent for reacting with a sample, 9 is a reagent disc holding the reagent container 8, and 10 is a bar code label bar code 11 attached to the reagent container 8 for identifying the reagent. Is a bar code reader for reading. Reference numeral 12 is a reagent dispensing device that dispenses the reagent in the reagent container 8 into the reaction container.

Reference numeral 13 denotes a sample syringe for sucking the sample in the sample container 1 to the sample dispensing device 7 and discharging it to the reaction container 6, and 14 denotes sucking the reagent to the reagent dispensing device 12 and discharging it to the reaction container 6. A reagent syringe 15 for performing the operation is an agitating device for agitating the sample and the reagent contained in the reaction container 6. Reference numeral 16 is a photometer for measuring the change in absorbance of the sample that has reacted with the reagent, 17 is a light source, 18 is a constant temperature bath for keeping the reaction container 6 at a constant temperature, 19 is a washing device for washing the reaction container 6 after analysis, and 20 is washing. This is a cleaning water supply device that supplies water to the device 19 and sucks waste liquid.

Reference numeral 21 is a computer for performing control processing and measurement signal processing. The computer 21 has a CPU.
Logarithmic amplifier (LOG amplifier) and AD via bus 22
A converter 23, a memory 24, a floppy disk drive 25, a printer 26, a keyboard 27 and a CRT display 28 are connected.

Reference numeral 29 is an external computer which has data relating to the sample and the reagent and which provides the data to the automatic analyzer. The identification code of the reagent and the sample obtained by the automatic analyzer is sent to this external computer 29,
Further, a communication device 30 and a communication line 31 for receiving data from an external computer and sending it to the automatic analyzer and a communication device 32 of the external computer are added.

To explain the general operation, during the analysis start, the bar code 4 for identifying the sample of the sample container 1 set on the sample disk 2 is first input by the input from the keyboard 27. Is read by the bar code reader 3. In addition, the reagent container 8 set in the reagent disk 9
The reagent identifying bar code 11 is read by the bar code reader 10. The read codes for identifying the reagent and the sample represented by these bar codes are read through the communication device 30, the communication line 31, and the communication device 32 for the external computer before the analysis. Sent to 29. The external computer 29 reads out various kinds of data corresponding to those identification codes from its own storage device, and similarly stores them in the communication device 30, the communication line 31, and the communication device 32 for external computer. Through automatic computer
Send it to computer 21. In the automatic analyzer, the data is used to calibrate with a standard sample, and then the sample is analyzed.

Further, not only during the analysis but also during the standby time when the analysis operation is not performed, the sample container 1 is operated by the input from the keyboard 27 in the same manner as during the start.
Of the sample identification bar code 4 is read by the bar code reader 3 and the reagent identification bar code of the reagent container 8 set on the reagent disk 9 is read by the bar code reader. Read by Da 10. The sample and reagent identification codes represented by these bar codes are used as the communication device 30 and the communication line 3.
1. Send to the external computer 29. External computer 2
9 reads various data corresponding to those identification codes from its own storage device, and similarly, automatically through the communication device 30, communication line 31, and communication device 29 for external computer. The data is sent to the computer 21 of the analyzer, and the computer 21 stores the sent data in the memory 24.
This data can also be used during analysis.

At the time of the next analysis start, the memory 2
4 is a code read from the bar code of the reagent and the sample as to whether or not the data has already been received from the external computer 21 at the time of the previous analysis start or at the request of the operator. It is also possible to check each code and make an inquiry to the external computer 21 only for those that are not in the memory.
FIG. 2 shows a schematic sample measurement time chart performed during one measurement cycle. When the start switch is turned on (A), the sample disk rotates and the sample to be sampled moves to the sampling position (sample suction position) (B), and the sample is sampled at that position ((A)). C).

Next, the position where the sampled sample should be discharged by rotating the reaction disk (sample discharge position)
And the sampled sample is discharged into the reaction container (D). Following this, the reagent disk rotates to move to the position where the desired reagent is to be sampled (E), where sampling of the reagent is performed, and the sampled reagent contains the sampled sample. (F). As a result, the reaction between the sample and the reagent is performed in the reaction container, and the reacted liquid is photometered (G).

The above steps are similarly performed for other specimens.

Reference numeral 33 is a stop indicator that indicates the stoppage of the sample disc 2 and the sample pipetting machine 7 while the automatic analyzer is operating. This emits, for example, blue light throughout the rest period,
The LE that blinks its blue light for a few seconds immediately before the startup starts
It is composed of a light-emitting body such as D (light emitting diode). This luminous body is arranged near the sample disk 2 as shown in FIG.

Here, the steps from the setting of the sample to the end of the analysis will be described with reference to FIGS. 4 and 5. As a premise of the description, the sample disk 2 is numbered in order at the position where the sample is set, and this is called the sample set position number.

First, it is determined whether or not the light emitter 33 is on (S1), and if it is not on, it waits until it is on (S2). If you confirm the lighting of the luminous body 33,
As shown in FIG. 5, the area 40 of the display screen of the CRT display 28 displays, for example, "Please set the sample to number 1", so after confirming the specified sample set position number ( S3), the sample is set at the position of the designated sample set position number (S4).
As the sample setting position where this sample should be set,
Among the vacant sample set positions of the sample disk 2, the one having the shortest waiting time until the sample sampling is selected. This is done by the computer 21.

Next, the operator is asked whether or not it is a fixed analysis item.
Judge (S5), and if the answer is Yes, CRT
The fixed analysis item input switch, which is arranged in the area 41 of the display 28 and has the fixed analysis item "GOT, GPT" written therein, is turned on (S6). Then, the fixed analysis item is stored in the memory 24 together with the sample set position number, and at the same time, the sample set position number "1" displayed in the area 40 is automatically incremented to set the next sample. The sample set position number is displayed instead. Also as the sample set position of the number displayed instead of this, one of the vacant sample set positions that has the shortest waiting time until sample sampling is selected.

After that, when the start switch written in the area 43, for example, "start" is turned on (S7), the set sample is analyzed (S7).
8) The process ends. This analysis is based on the time chart shown in FIG.
It is carried out according to G.

If the determination in step (S5) is No, the analysis item change switch placed in the area 42 and labeled as "item change" is turned on (S9), and the item to be changed, for example LDH, is selected. The key board 27 is operated to key in. As a result, the item is stored in the memory 24 together with the sample set position number. After that, the start switch is turned on (S7), and the analysis is performed according to the time chart shown in FIG. 2 (S8).
finish.

To set the samples one after another, it is sufficient to repeat the steps before step (S) and finally turn on the start switch.

As is apparent from the above, when the samples are set at a plurality of sample set positions, the empty sample set position to which each of the samples is to be set is the sample set position among the plurality of sample set positions. Be sure to instruct before each set of. Therefore, when setting the sample, the operator is informed of the sample setting position at which the sample should be set, so the operator only has to set the sample at the specified sample setting position. Therefore, when the sample is set, there is no adverse effect on the acquisition of the analytical data of the already set sample.

Further, the designated sample set position is the sample set position where the waiting time until sampling is shortest among a plurality of vacant sample set positions. Therefore, the analysis waiting time can be shortened, and the analysis time as a whole can be shortened.

Further, there is a means for instructing the stop of the operation of the sample holding means and the suction and discharge means of the sample so that the sample can be set while the instruction is issued. Therefore, even an amateur can safely set the sample without any danger.

[0039]

According to the present invention, there is provided an automatic analyzer which, when a sample is set, does not adversely affect the acquisition of the analytical data of the already set sample.

When there are a plurality of free sample set positions, the sample set position designated by the apparatus is the sample set position where the waiting time until sampling is the shortest. Shortening of
Therefore, the analysis time as a whole can be shortened.

Further, there is a means for displaying the operation stop of the sample holding means and the sample inhalation and discharge means during the operation stop time, and the sample can be set while the display is displayed. Even an amateur can safely set a sample without risk.

[Brief description of drawings]

FIG. 1 is a conceptual diagram of the overall configuration of an automatic analyzer according to an embodiment of the present invention.

FIG. 2 is a diagram showing a general time chart for sample measurement.

FIG. 3 is a schematic top view around the sample disc, reagent disc, and reaction disc of FIG.

FIG. 4 is a diagram showing an example flow chart showing steps from setting of a sample to the end of analysis according to the present invention.

5 is a diagram showing an example display screen of the CRT display of FIG.

[Explanation of symbols]

1: sample container, 2: sample disk, 5: reaction disk, 6: reaction container, 7 sample dispenser, 8: reagent container, 9: reagent disk, 28: CRT display, 3
3: stop indicator, 40: sample set position number display area,
41: analysis item input switch area, 42: analysis item change switch area, 43: start switch area.

Claims (10)

[Claims] 1. An automatic system comprising: a sample holder having a plurality of sample set positions and setting and holding the samples at those sample set positions; and means for sampling and analyzing the set samples. In the analyzer, when setting the samples at the plurality of sample setting positions, among the plurality of sample setting positions, the empty sample setting positions where the respective samples should be set are the respective sample setting positions. An automatic analyzer characterized in that it is provided with means for instructing prior to the setting. 2. The automatic analyzer according to claim 1, wherein the designated sample set position has the shortest waiting time until sampling among a plurality of vacant sample set positions. An automatic analyzer characterized in that the sample set position is where 3. The automatic analyzer according to claim 1 or 2, wherein the sample set position indicating means has a display screen, and sets each of the samples among the plurality of sample set positions. An automatic analyzer, characterized in that the vacant sample set position to be displayed is displayed on the display screen. 4. An automatic system comprising: a sample holder having a plurality of sample set positions and setting and holding samples at these sample set positions; and means for sampling and analyzing the set samples. In the analyzer, when setting the samples at the plurality of sample setting positions, among the plurality of sample setting positions, the empty sample setting positions where the respective samples should be set are the respective sample setting positions. 2. An automatic analyzer comprising: a means for displaying prior to the setting of 1. and a means for selecting an analysis item of the set sample. 5. The automatic analyzer according to claim 4, wherein the designated sample set position has the shortest waiting time until sampling among a plurality of vacant sample set positions. An automatic analyzer characterized in that the sample set position is where 6. The automatic analyzer according to claim 4, wherein the sample set position indicating means has a display screen, and sets each of the samples among the plurality of sample set positions. An automatic analyzer, characterized in that the vacant sample set position to be displayed is displayed on the display screen. 7. A sample holding unit having a plurality of sample setting positions and setting and holding the samples at those sample setting positions, and moving the sample set at the sample setting positions to a first position. And a means for driving the sample holding means, a means for inhaling the sample moved to the first position and ejecting the inhaled sample at the second position, and a means for analyzing the ejected sample. In the automatic analyzer, wherein when setting the sample at the plurality of sample set positions, among the plurality of sample set positions, the empty sample set positions where each of the samples should be set are An automatic analyzer characterized in that it comprises means for displaying prior to each set of specimens. 8. The automatic analyzer according to claim 7, further comprising means for displaying an operation stop of the sample holding means and the sample inhaling and discharging means during an operation stop time, and the display is issued. An automatic analyzer characterized in that the sample can be set while the apparatus is in operation. 9. The automatic analyzer according to claim 8, wherein the operation stop display means is a light emitter, and the light emitter is arranged in the vicinity of the sample holding means. Automatic analyzer to do. 10. The automatic analyzer according to claim 7, wherein the designated sample set position is a sample inhalation of a plurality of vacant sample set positions. An automatic analyzer characterized by being at the sample set position where the waiting time until is shortest.