JPH06327764A - Attaching and detaching mechanism of artificial heart - Google Patents

Abstract

PURPOSE:To provide the attaching and detaching mechanism of the artificial heart which is constituted to eliminate repetition of incision and suture of the apex part of the viable heart, to facilitate mounting and removing for exchanging of the artificial heart body, to permit rapid exchange, to prevent extrusion of the blood in the heart to the outside and to close the open part of the apex part by mounting a hole plug after removal of the artificial heart body and has high efficiency in mounting of the artificial heart body to the apex part. CONSTITUTION:The parts of this attaching and detaching mechanism of the artificial heart which are to be mounted in the apex part are composed of a sawing cuff, apex part ring 12, a sealing member 18 and a packing member. The mechanism is constituted to permit the easy mounting and removing of the mechanism for the purpose of exchanging the artificial heart body and to permit the rapid exchange by such means as pressing of the sealing member by a lock nut, pressing of the sealing member by an eccentric lever for tightening, using a shape memory alloy for the apex part ring, using of a balloon for the sealing member and using of a one easy step joint.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an attachment / detachment mechanism for an implantable auxiliary artificial heart which is used by being embedded in a ventricle of a human heart, that is, a left ventricle or a right ventricle.

[0002]

2. Description of the Related Art Conventional artificial hearts include various types such as a diaphragm type, a sack type, an axisymmetric type, a centrifugal type, and a pusher plate type, all of which are used in place of or in place of the human heart. It is a form of sending blood by bypassing. By the way, recently, an auxiliary artificial heart has been developed which is buried in the ventricle of the human heart and sends blood in the ventricle into the aorta from the tip of a nozzle that penetrates the aortic valve or the like. FIG. 3 is an enlarged cross-sectional view showing an embodiment in which the artificial heart is attached to the left ventricle of the human heart.
In FIG. 3, A is the heart, B is the left ventricle, C is the apex, D is the left atrium, E is the mitral valve, F is the aortic valve, G is the aorta, and 1 is an artificial heart embedded in the left ventricle B. Is. The artificial heart 1 is composed of an apex ring 2 embedded in an apex C of a human heart A and an artificial heart body 3, and the apex ring 2 has a short cylindrical shape having a collar portion. Heart A
The apex portion C is incised and penetrated through the apex portion C to be implanted. The artificial heart main body 3 includes a pump unit 4, a nozzle unit 6 provided at the tip of the pump unit 4, and a drive unit 5 provided at the base end of the pump unit 4.
The nozzle portion 6 is inserted into the left ventricle B through the apex ring 2, and the nozzle portion 6 is further inserted into the aorta G through the central portion of the aortic valve F. Further, liquid tightness is secured between the apex ring 2 and the artificial heart body 3 by an ordinary sealing mechanism, for example, a sealing member 8. Such an artificial heart does not impair the function of the heart even if it is embedded, and is configured to send the blood, which is insufficient only by the beating of the heart, to the artery. In addition, since blood is sent by the heartbeat, even if the artificial heart stops, blood is sent by the heartbeat, so there is an advantage that the safety is high and the burden on the patient is small. . The auxiliary artificial heart embedded in the ventricle of the above heart is used for recovery of ventricular function on the premise of withdrawal, bridge use up to transplantation without presumption of withdrawal, and permanent implantation use. It is embedded in the ventricle for the purpose of which it must be secured in some way by providing an insertion hole in the apex of the heart. Further, if the heart function is restored after the attachment, it is necessary to remove the artificial heart and close the opening part by some method. In addition to bridge use without permanent removal and permanent burial, even for short-term burial use until recovery of cardiac function assuming removal, several units are required based on the current degree of perfection of the artificial heart. Treatment must be continued while exchanging.

[0003]

However, since it is medically unfavorable to repeatedly incise and suture the apex wall of the heart every time the artificial heart is replaced, this attachment part is used for replacing the artificial heart. Easy to install and remove
In addition, it is necessary to have a mechanism that can reliably and reliably prevent blood in the ventricle from being pushed out by the heartbeat. There is also a method of suturing the opening after removal,
In order to reduce the number of sutures even once, and in case it becomes necessary to reattach it, keep the hole closed with a removable stopper without affecting the natural movement of the living body or heart. There is a need. To deal with such situations,
It is easy to attach and detach the auxiliary artificial heart to the living heart,
It can be replaced quickly, and also prevents the blood in the heart from being pushed out by the contraction pressure of the heart.
Until now, no mechanism has been put into practical use in which the opening after removal is closed with a plug.

[0004]

The attachment / detachment mechanism for an artificial heart according to the present invention is an auxiliary artificial heart that is used by inserting it into the ventricle of the human heart, and incises the apex of the human heart. A tubular apex ring that is embedded and fixed in the lever apex, and an artificial heart body having a drive unit are provided, and the apex to which the artificial heart body is attached has an incised apex. A circular sewing cuff that is fixed by suture, a tubular apex ring that engages with the sewing cuff and is embedded and fixed in the apex, and the apex ring that is locked to the proximal end side of the artificial heart body. A seal member that engages with, a drive unit side packing that is mounted between the neck and the apex ring on the drive unit side of the artificial heart body, and the seal member and the apex ring on the ventricle side. A ventricular packing to be mounted between A closed hole plug for closing the apex ring after taking out the engineered heart body, fixing the apex ring and the seal member by screwing, and mounting the artificial heart body on the apex Let Further, a closed hole plug having a screw to be engaged with the apex ring is attached to the apex of the artificial heart body after removal.
Further, the artificial heart body has a screw formed on the neck portion on the drive unit side, a tightening nut screwed with the screw, and the seal member using an elastic packing, and the seal member is formed by the tightening nut. Compress and attach the artificial heart body to the apex. Further, at the apex portion of the artificial heart main body after removal, a closing plug having a tightening ring and a tightening eccentric lever actuates the tightening eccentric lever to press the seal member to compress and fix it to the apex ring. Further, a balloon connected to a conduit having an injection part is used as the sealing member, and the artificial heart body is attached to the apex. Further, a closed-hole plug using a balloon connected to a conduit having an injection portion is locked to the apex ring at the apex after removal of the artificial heart body. The artificial heart body is attached to the apex by using a shape memory member for the apex ring or a ring-shaped shape memory member arranged at a plurality of locations as the seal member. Further, the apex ring provided with an opening for engaging with the artificial heart body, a collet chuck and a release bush fixed to the apex ring, and locked to the neck portion on the drive side of the artificial heart body. A sealing member, and a tightening packing sandwiched between the artificial heart body and the tip of the collet chuck, the seal member is coupled and fixed to the collet chuck, and the artificial heart body is attached to the apex. It is characterized by being attached.

[0005]

[Function] By fixing the apex ring and the seal member by screwing, and by making the closed hole plug after removal into a screw type, the artificial heart body can be easily attached and detached for replacement,
And it can be done reliably. Further, a screw formed on the neck portion on the drive side of the artificial heart body, a tightening nut, and a seal member are provided, the seal member is compressed and fixed by the tightening nut, and a tightening ring is attached to the closed hole plug after removal. An eccentric lever for tightening is provided, and the seal member is compressed and fixed by the eccentric lever for tightening, whereby the artificial heart main body can be easily attached and detached for replacement. Further, by using a balloon connected to a conduit having an injection portion as a seal member, the balloon is connected to the apex ring, and the closed hole plug after removal is filled with the balloon connected to the conduit having an injection portion. The attachment and detachment of the artificial heart body for replacement can be performed easily and reliably. Further, by using a shape memory member as the seal member or disposing ring-shaped shape memory members at a plurality of locations, the artificial heart body can be easily attached and detached. In addition, an apical ring having an opening, a collet chuck, a release bush, and a tightening packing are provided, and the release bush is coupled and fixed to the collet chuck, so that the artificial heart body can be easily attached and detached. be able to.

[0006]

Embodiments of the present invention will be described with reference to the drawings.
FIG. 1 is a partially enlarged cross-sectional view showing a state in which an artificial heart is attached to the left ventricle of the human heart according to the first embodiment of the present invention. In FIG. 1, B is the left ventricle, C is the apex of the heart, 3 is an artificial heart body inserted into the left ventricle B, and 5 is a drive unit of the artificial heart body 3, which contains a motor. Reference numeral 11 denotes a circular sewing cuff that is sutured and fixed to the incised apex C, 12 is a tubular apex ring that engages with the sewing cuff 11 and is embedded and fixed in the apex C and has a threaded portion formed in a tubular shape, 18 Is a seal member having a threaded portion that is engaged with the neck portion of the artificial heart body 3 on the drive portion side and is screwed with the threaded portion of the apex ring 12, and 14 is between the apex ring 12 and the seal member 18. The ventricle-side packing 15 is mounted, and the reference numeral 15 is a drive unit-side packing mounted on the drive unit 5 side of the artificial heart body 3. The sewing cuff 11, the apex ring 12, and the ventricle-side packing 14 are formed as one assembled part, and are sewn and fixed together with the sewing cuff 11 to the apex C previously cut. In addition, the outer peripheral portion of the apex ring 12 on the left ventricle B side is flared in a brim shape, and is difficult to come off after being sutured to the apex C. By fitting the artificial heart body 3 to the human heart by screwing together the apex ring 12 and the threaded portion of the seal member 18, the ventricle side packing 14 and the drive section side packing 15 are pressed and the airtightness of the threaded portion is maintained. Therefore, even when the heart beats, blood in the ventricle is not pushed out and body fluid does not enter the screw part. In addition, each part is made of a material and shape having excellent biocompatibility, and the apex ring 12 and the threaded portion of the seal member 18 are made of a material having a heat insulating effect and a vibration absorbing effect. After mounting, heat or vibration generated by the motor built in the drive unit 5 is not transmitted to the apex C. FIG. 2 shows the first of the present invention.
FIG. 7 is a partial enlarged cross-sectional view showing a state in which a closed hole plug is attached after the artificial heart in the embodiment of FIG. In FIG. 2, after the artificial heart body 3 is detached, the closure plug 17 is quickly inserted into the apex ring 12 to close the opened apex. The closed-hole plug packing 16 is assembled in advance to the closed-hole plug 17, and the closed-hole plug 17 is formed with a threaded portion to be screwed into the threaded portion of the apex ring 12. By screwing the closure plug 17 to the apex ring 12, it is possible to quickly attach the artificial heart after detachment, and after tightening, air tightness can be secured by the ventricle side packing 14 and the closure plug packing 16. According to this mechanism, the artificial heart body and the closed hole plug can be quickly and reliably attached and detached.

FIG. 4 is a partially enlarged sectional view showing a state in which an artificial heart is attached to the left ventricle of the human heart according to the second embodiment of the present invention. In FIG. 4, B is the left ventricle, C is the apex of the heart, 3 is an artificial heart body inserted into the left ventricle with a screw formed on the neck of the drive side, and 5 is the drive section of the artificial heart body 3 and the motor is It is built in. Reference numeral 21 is a circular sewing cuff that is sutured and fixed to the incised apex C, 22 is a tubular apex ring that is engaged with the sewing cuff 21 and is embedded and fixed in the apex C, and 28 is the artificial heart body 3 and the apex. A sealing member made of an elastic packing that engages with the partial ring 22, and 24 is a tightening nut that is screwed with a threaded portion formed in the artificial heart body 3. The apex ring 22 is sewn together with the sewing cuff 21 to the apex C previously cut,
Fixed. The artificial heart body 3 inserted into the ventricle through the apex ring 22 can be attached to the apex ring 22 by compressing the seal member 28 by tightening the tightening nut 24. Also, the apex ring 2
The inner central part of 2 is expanded in a drum shape, and the ends on both sides are also expanded in a trumpet shape, and the seal member 28 is compressed following the shape of the apex ring 22. 3 can be fixed so that it does not come off even when the heart beats. Since the material of the seal member 28 has heat resistance and elasticity, it can keep the ventricle airtight as a packing function and also absorbs vibrations and heat generated by the motor and does not transmit them to the apex. FIG. 5 shows the second aspect of the present invention.
FIG. 7 is a partial enlarged cross-sectional view showing a state in which a closed hole plug is attached after the artificial heart in the embodiment of FIG. In FIG. 5, after the artificial heart body 3 is detached, a closure plug 27 is quickly inserted into the apex ring 22 to close the opened apex. The closing plug 27 including the seal member 28, the tightening ring 25 and the tightening eccentric lever 29 is preassembled, and the outer diameter of the seal member 28 is made slightly smaller than the inner diameter of the apex ring 22 as described above. It can be easily inserted into the apex ring 22 due to its presence. When inserting into the apex ring 22, the tightening ring 25 and the tightening eccentric lever 29 are free, and after inserting, the tightening eccentric lever 29 is tilted as shown in the drawing to press the tightening ring 25 and the sealing member. Two
It can be attached by compressing 8. The sealing member 28 may be compressed by the tightening nut structure as shown in FIG.
The same effect can be obtained by other methods that can be performed speedily.

FIG. 6 is a partially enlarged sectional view showing a state in which an artificial heart is attached to the left ventricle of the human heart according to the third embodiment of the present invention. In FIG. 6, B is the left ventricle, C is the apex, 3 is the artificial heart body, and 5 is the drive unit of the artificial heart body 3, and the motor is built in. Reference numeral 31 is a circular sewing cuff that is sutured and fixed to the incised apex C, 32 is a tubular apex ring that engages with the sewing cuff 31 and is embedded and fixed in the apex C, and the apex ring 32 is previously incised. The sewing cuff 31 is sutured and fixed to the apex C of the heart. 38 is a seal member using a balloon in which the conduit 33 and the injection part 34 are connected, and is assembled to the artificial heart body 3. The conduit 33 is a tube through which a filler for inflating the balloon passes, and the filler is injected from the injection part 34. After attaching the artificial heart body 3 to the apex ring 32, the injection part 34
The filler is injected through the conduit 33 to a predetermined pressure with a more puncture needle-shaped nozzle, and the seal member 38 using a balloon is inflated to be fixed. After filling, when the puncture needle-shaped nozzle is pulled out, the injection part is closed and the filler does not leak. Further, both ends of the apex ring 32 are jaw-shaped, and if the seal member 38 using a balloon is inflated, the artificial heart body 3 will not come off even when the heart beats. Furthermore, due to the packing effect of the seal member 38, blood is not pushed out, and it is also possible to block heat, vibration, etc. from the drive unit 5. When detaching the artificial heart body 3, the conduit 33 may be cut off, and the filler can be released at once so that the detachment can be done quickly.
The filler may be gas or liquid and is preferably harmless to the human body. FIG. 7 is a partially enlarged cross-sectional view showing a state in which a closed hole plug is attached after the artificial heart according to the third embodiment of the present invention is detached. In FIG.
37 is a closed-hole plug using a balloon in which a conduit 35 and an injection part 36 are connected, and is attached to the apex ring 32 after detaching the artificial heart body 3. The apex ring 32 can be closed by inserting the closure plug 37 into the apex ring 32 and expanding it in the same manner as described above. When removing the closed plug 37, the conduit 35 may be cut and the filler may be removed in the same manner as described above.

FIG. 8 is a partially enlarged sectional view showing a state in which an artificial heart is attached to the left ventricle of the human heart according to the fourth embodiment of the present invention. In FIG. 8, B is the left ventricle, C is the apex, 3 is the artificial heart body, and 5 is the drive unit of the artificial heart body 3, and the motor is built in. Reference numeral 41 is a circular sewing cuff that is sutured and fixed to the incised apex C, and 42 is a tubular apex ring made of a shape memory alloy that is engaged with the sewing cuff 41 and embedded and fixed in the apex C. The apex ring 42 is sewn and fixed together with the sewing cuff 41 to the apex C that has been incised in advance. A seal member 48 is fixed to the apex ring 42 and engages with the artificial heart body 3. Since the apex ring 42 has a diameter slightly larger than the outer diameter of the artificial heart body 3 except for the body temperature, the artificial heart body 3 can be attached to the apex ring 42. After the artificial heart body 3 is attached, if the temperature of the apex ring 42 is returned to the same temperature as the body temperature, the apex ring 42 contracts to a small diameter, and the artificial heart body 3 is clamped and fixed via the seal member 48. To do. The engaging portion of the artificial heart body 3 with the apex ring 42 has a small diameter, and is difficult to be removed after being fixed to the apex ring 42. Moreover, the blood in the ventricle B is not pushed out by the seal member 48, and the vibration and heat of the drive unit 5 are not transmitted to the apex C. Although the shape memory alloy is used for the apex ring 42 in the embodiment of FIG. 8, a shape memory alloy may be used for the artificial heart body 3.
The material is not limited to this as long as it has a shape memory function.

FIG. 9 is a partially enlarged sectional view showing a state in which an artificial heart is attached to the left ventricle of the human heart according to the fifth embodiment of the present invention. In FIG. 9, B is the left ventricle, C is the apex of the heart, 3 is the artificial heart main body, and 5 is the drive unit of the artificial heart main body 3, which has a built-in motor. Reference numeral 51 is a circular sewing cuff that is sutured and fixed to the incised apex C, 52 is a tubular apex ring that engages with the sewing cuff 51 and is embedded and fixed in the apex C, and the apex ring 52 is previously incised. It is sutured and fixed together with the sewing cuff 51 to the apex C of the heart. Reference numeral 58 is a seal member disposed at two positions of the artificial heart body 3, and shape memory alloys 58a and 58b formed in a wire shape are incorporated therein. Sealing member 58
The tip portion of is smaller in diameter than the inner diameter of the apex ring 52 at a temperature other than the body temperature and can be inserted into the apex ring 52. When the seal member 58 is reheated to the same temperature as the body temperature after mounting the artificial heart body 3, the shape memory alloy 58
The dimensions of a and 58b are expanded, and the seal member 58 is pressed against the groove of the apex ring 52 to mount and fix the artificial heart body 3. In this state, the blood in the ventricle B is not pushed out by the seal member 58, and the vibration and heat of the drive unit 5 are not transmitted to the apex C. The shape memory alloys 58a, 58b
The material is not limited to this as long as it has a shape memory function, and it may be at two or more locations.

FIG. 10 is a partially enlarged sectional view showing a state in which an artificial heart is attached to the left ventricle of the human heart according to the sixth embodiment of the present invention. In FIG. 10, B is the left ventricle and C
Is an apex of the heart, 3 is a main body of the artificial heart, and 5 is a drive unit of the main body 3 of the artificial heart, in which a motor is incorporated. Reference numeral 61 is a circular sewing cuff that is sutured and fixed to the incised apex C, and 62 is a tubular apex ring that engages with the sewing cuff 61 and is embedded and fixed in the apex C.
Is sewn and fixed together with the sewing cuff 61. 63 is a release bush incorporated in the apex ring 62, 64
Is a collet chuck incorporated in the apex ring 62, 6
Reference numeral 5 denotes a tightening packing that is sandwiched between the apex ring 62 and the tip of the collet chuck 64. Further, a taper is formed on the base end of the artificial heart main body 3 on the drive side and the release bush 63. A seal member 68 is fixed to the artificial heart body 3, and is made of an elastic material having a heat insulating effect and a vibration absorbing effect. To attach the artificial heart body 3 to the apex ring 62, push it into the apex ring 62,
It suffices to pull back a little, and by pulling back a little, one end of the collet chuck 64 is bite and fixed to the seal member 68 fixed to the outer periphery of the artificial heart body 3, and the other end is tightened via the tightening packing 65. The seal member 68 is pressed and fixed. This maintains airtightness. Further, the taper of the proximal end of the artificial heart does not pull the artificial heart toward the ventricle. Also,
When detaching, the release bush 63 is pushed in, and if the bite of the collet chuck 64 is released, the artificial heart body 3
Can be pulled out. Although the illustration of the closure plugs for the apex ring closure in the fourth, fifth, and sixth embodiments of the present invention is omitted, the same idea as in the first, second, and third embodiments is considered. It goes without saying that a closure plug having the same shape and size as the engaging portion of the artificial heart body with the apex ring of the artificial heart body may be prepared based on the above. In addition to the above, the present invention can be applied to the joining of the heart and the blood vessel, the joining of the blood vessel and the blood vessel, the joining of the heart and other devices, and the same effects can be obtained.

[0012]

As described in detail above, according to the present invention, the operation of attaching, detaching the artificial heart body to the apex and closing the apex after the detachment can be performed easily and quickly. You can In addition, since it can be securely fixed, the heartbeat does not cause disengagement and the blood in the ventricle is not pushed out. The apex ring is attached to the apex by cutting and suturing the apex, but once attached, the artificial heart body and the closure plug can be attached to and removed from the apex ring any number of times. Only one incision and suturing of the apex wall is required.
This is surgically favorable. Further, since each part and each part forming them are formed in a size, shape and material in which biocompatibility is taken into consideration, hemolysis and thrombus are not generated, and movement of the living heart is not disturbed. Further, since the number of constituent parts is small and the structure is simple, it is possible to provide a highly reliable artificial heart attachment mechanism for a long period of time.

[Brief description of drawings]

FIG. 1 is a partially enlarged cross-sectional view showing a state in which an artificial heart is attached to the left ventricle of the human heart according to the first embodiment of the present invention.

FIG. 2 is a partially enlarged cross-sectional view showing a state in which a closure plug is attached after the artificial heart according to the first embodiment of the present invention is detached.

FIG. 3 is an enlarged cross-sectional view showing an embodiment in which an artificial heart is attached to the left ventricle of the human heart.

FIG. 4 is a partially enlarged cross-sectional view showing a state in which an artificial heart is attached to the left ventricle of the human heart according to the second embodiment of the present invention.

FIG. 5 is a partially enlarged cross-sectional view showing a state in which a closed hole plug is attached after the artificial heart according to the second embodiment of the present invention is detached.

FIG. 6 is a partially enlarged cross-sectional view showing a state in which an artificial heart is attached to the left ventricle of the human heart according to the third embodiment of the present invention.

FIG. 7 is a partially enlarged cross-sectional view showing a state in which a closed hole plug is attached after the artificial heart according to the third embodiment of the present invention is detached.

FIG. 8 is a partially enlarged cross-sectional view showing a state in which an artificial heart is attached to the left ventricle of the human heart according to the fourth embodiment of the present invention.

FIG. 9 is a partially enlarged cross-sectional view showing a state in which an artificial heart is attached to the left ventricle of the human heart according to the fifth embodiment of the present invention.

FIG. 10 is a partially enlarged cross-sectional view showing a state in which an artificial heart is attached to the left ventricle of the human heart according to the sixth embodiment of the present invention.

[Explanation of symbols]

1 ... Artificial heart, 2, 12, 22, 32, 42, 52, 62 ... Apex ring, 3 ... Artificial heart body, 4 ... Pump section, 5 ... Drive section, 6 ... Nozzle part, 8, 18, 28, 38, 48, 58, 68 ... Sealing member, 11, 21, 31, 41, 51, 61 ... Sewing cuff, 14 ... Ventricular side packing, 15 ... Drive side packing, 16 ... Closure plug packing, 17, 27, 37 ... Closure plug, 24 ... Tightening nut, 25 ... Tightening ring, 29 ... Tightening Eccentric lever for attachment, 33, 35 ... Conduit, 34, 36 ... Injection part, 58a, 58b ... Shape memory alloy, 63 ... Release bush, 64 ... Collet chuck, 65 ... Tightening packing, A ... Heart, ... the left ventricle, C ··· apex

Claims (10)

[Claims] 1. A supplementary artificial heart which is used by inserting it into a ventricle of a human heart, and is a tube which is incised by incising the apex of the human heart and embedded and fixed in the apex. A heart-shaped apex ring, and an artificial heart body having a drive unit, wherein the apex portion to which the artificial heart body is attached, a circular sewing cuff that is sutured and fixed to the incised apex portion, A tubular apex ring that engages with the sewing cuff and is embedded and fixed in the apex; a seal member that is locked to the proximal end side of the artificial heart body and that engages with the apex ring; A drive unit side packing mounted between the neck of the drive unit side of the heart body and the apex ring, and a ventricle side packing mounted between the seal member and the apex ring on the ventricle side, The apex ring after removal of the artificial heart body Detaching mechanism of the artificial heart which is characterized by comprising and a closed porosity plug to closed pores. 2. The artificial heart according to claim 1, wherein the apex ring and the seal member are fixed by screwing, and the artificial heart body is attached to the apex. 3. An artificial heart body comprising a screw portion formed on a neck portion on a drive portion side, a tightening nut screwed with the screw portion, and the seal member using an elastic packing. Compress the sealing member with a tightening nut,
The artificial heart according to claim 1, wherein the artificial heart body is attached to the apex. 4. The artificial heart according to claim 1, wherein a balloon connected to a conduit having an injection portion is used as the sealing member, and the artificial heart body is attached to the apex. 5. A shape memory member is used for the apex ring,
The artificial heart according to claim 1, wherein the artificial heart body to which the seal member is attached is attached to the apex. 6. The artificial heart according to claim 1, wherein ring-shaped shape memory members are arranged at a plurality of positions as the seal member, and the artificial heart body is attached to the apex. 7. The apex ring provided with an opening for engagement with the artificial heart body, a collet chuck and a release bush fixed to the apex ring, and a neck portion of the artificial heart body on the side of a drive unit. And a tightening packing that is sandwiched between the artificial heart body and the tip of the collet chuck. The artificial heart body is coupled and fixed to the collet chuck. The artificial heart according to claim 1, which is characterized in that. 8. The artificial heart according to claim 2, wherein the closure plug is formed with a screw that is locked to the apex ring. 9. The artificial body according to claim 3, wherein the closed hole plug comprises a tightening ring and a tightening eccentric lever, and the seal member is compressed and fixed by the tightening eccentric lever. heart. 10. The artificial heart according to claim 4, wherein the closure plug is locked to the apex ring by using a balloon connected to a conduit having an injection part.