JPH0584178B2 - - Google Patents

Description

Detailed Description of the Invention [Industrial Application Field] The present invention is an improvement in a drug solution injection tool that injects a drug solution press-fitted into a rubber-like elastic container into a patient's body by utilizing the contraction force of the container. Regarding.

[Conventional technology]

The applicant previously filed Japanese Patent Application No. 62-204791,
No. 294809, No. 63-160526, and No. 63-162271 propose a drug injection device that utilizes the force of contraction of a rubber-like elastic container.

For example, as shown in FIG.
An inner shaft 32 is slidably housed inside the inner shaft 1, and an inner shaft 32 is provided outside the shafts so as to cover both shafts. Balloon 3 made of elastic material tightly fixed
It has a balloon part a consisting of 3.

According to these liquid drug injection devices, the balloon is tightly fixed to the outer shaft and the inner shaft slidably inserted into the outer shaft, so that the balloon can be expanded not only in the radial direction but also in the axial direction. When the balloon is deflated, the inner shaft is guided by the outer shaft, and the balloon completely returns to its original state, which has the effect of extremely reducing the amount of drug remaining. It is.

[Problem to be solved by the invention]

However, the above-mentioned liquid injection device is
In the injection device of No. 62-204791, the rubber-like elastic container, that is, the balloon, is not housed in a sealed container, so there are problems such as the medical solution scattering when the balloon bursts, and problems such as three-way stopcocks, etc. Since the stopcock is used to inject and dispense the chemical solution into the balloon, there is a risk that the liquid may leak, even if only slightly, or the chemical solution may become cloudy at the stopcock, or the liquid may leak from the stopcock. There was a fear that bacteria and other substances could enter the drug solution. Also, patent applications No. 62-294809, No. 63-160526, No. 63-
In the injection tool of No. 162271, when injecting the drug solution, it is necessary to use a syringe to force the drug solution into the container from the injection port side against the force that tries to contract the container, and this type of injection tool has 1 sticker
Because of this, when the needle was removed, the liquid inside could temporarily squirt out due to internal pressure, which was a problem.

Moreover, since the chemicals used in these devices for continuously injecting chemicals in small amounts are often expensive, the squirting of chemicals is not only an economic loss;
For example, highly toxic substances such as anti-cancer drugs have been a problem since the handlers are exposed to danger.

The present invention has been made in view of these problems, and is a drug solution injection tool for injecting a drug solution press-fitted into a rubber-like elastic container into a patient's body using the contraction force of the container. To provide a drug solution injection tool that does not cause temporary ejection of drug solution when a subsequent injection needle is pulled out.

[Means to solve the problem]

In order to solve the above-mentioned problems, the present invention involves pressurizing a drug solution into an easily inflatable container made of a rubber-like elastic material, and utilizing the contracting force of the expanded container to press the drug into the container. In the device for discharging a medicinal solution and injecting it into the body, the container has a common passage for injecting and discharging the medicinal solution, and the common medicinal solution passage has an opening through which a syringe needle is inserted. The liquid medicine passage is sealed liquid-tightly with a stopper made of a rubber-like elastic material, and a means for obstructing the discharge of the medicine is provided in the part of the medicine passage inside the stopper.

[Effect]

According to the above configuration, the means for obstructing the ejection of the medicinal solution inside the stopper at the mouth of the medicinal solution passage resists the contraction force of the rubber-like elastic container and causes the medicinal solution to be ejected from the container. This prevents the contraction force of the container from being applied directly to the stopper at the mouth. Therefore, when the injection needle is removed from the stopper at the mouth after the medical solution has been press-fitted, the drug does not spray out from the stopper.

〔Example〕

Next, embodiments of the present invention will be described based on the drawings.

FIG. 1 is a plan view of one embodiment of the drug injection device of the present invention, showing a state in which the liquid guide needle is not inserted into the stopper, and FIG. 2 is a balloon portion of the injection device shown in FIG. 1. FIG. 3 to FIG. 5 are enlarged sectional views of main parts in other embodiments.

In FIGS. 1 and 2, reference numeral I denotes a chemical liquid injection tool according to an embodiment of the present invention, which is composed of a balloon part A, a housing B, a flow rate control part C, a chemical liquid injection tube D, and a connector E. There is.

The balloon part A is a part filled with a medicinal solution and a driving part that moves the medicinal solution to the injection site of the human body, and includes a cylindrical outer shaft 1 and an inner shaft slidably housed inside the outer shaft 1. 2 and a balloon 3 provided outside both of these shafts, the outer shaft being hollow in the axial direction and capable of fluid communication with a chemical liquid passage 7 of a housing B, which will be described later. The housing B prevents the balloon 3 from being damaged due to contact with a sharp object outside, and also prevents the chemical solution from scattering to the outside in the event that the balloon leaks due to a defect such as a pinhole in the balloon itself. A substantially cylindrical protrusion 5 is formed on the end surface 4 of the housing B coaxially with the outer axis. The hollow portion of the protruding portion 5 passes through the end surface 4 of the housing B, and is formed into a chemical liquid passage 7 that can communicate with the hollow portion of the outer shaft 1 of the burn portion A. The flow rate control section C at the rear of the housing B is a part that controls the flow rate of the chemical solution, and is provided with a pipe having at least one microscopic hole in the flow path of the chemical solution, and allows all the chemical solution to pass through the microscopic hole. The flow rate is controlled. A liquid guiding needle 13 is attached to one end of the flow rate control section C.

Hereinafter, the chemical liquid passage 7 portion will be explained in detail.

The chemical liquid passage 7 is a part formed so as to be able to communicate fluidly with the hollow part of the balloon part A and the flow rate control part C, and a mouth part plug 8 is provided at the mouth part of the medicine liquid passage 7.
A stopper 9 is provided in the inner part as a means for obstructing the discharge of the chemical solution. The mouth plug body 8 is made of a rubber-like elastic material through which an injection needle can be inserted, and seals the mouth of the drug solution passage 7 liquid-tightly.
The mouth plug body 8 is preferably fixed under pressure by a cap-like member 6 having an opening at the center of the top surface. Butyl rubber, silicone rubber, nitrile butadiene rubber, etc. are generally used as the rubber-like elastic body, and the same materials as the housing B can be used as the material for the cap member 6, such as polyvinyl chloride, polypropylene, polycarbonate, etc. Examples include polyethylene.

The means for obstructing the ejection of the drug solution is inserted and fixed in the drug solution passage 7 (including the end of the hollow part of the outer shaft 1 of the balloon part A on the drug solution passage side) inside the mouth plug 8. It has the role of preventing ejection and leakage of chemical liquid due to compression. In addition to the stopper 9 shown in FIG. 2, third to fifth means for obstructing the discharge of the chemical solution
Check valves 19, 29, 39 as shown in the figure can also be used.

The stopper 9 is made of a rubber-like elastic material that can be pierced with a needle like the mouth stopper 8, and the lid 10 of the stopper 9 has an annular groove formed by the step portions 11 and 12. It is fitted inside. When injecting and dispensing a medicinal solution, the opening is penetrated together with the mouth stopper 8 by a syringe needle. By providing this stopper 9, when the injection needle is pulled out from the rubber stoppers 8 and 9 after injecting the drug solution, when the needle is pulled out from the stopper 9, there is a space between the stopper 9 and the mouth stopper 8. There was almost no ejection of the chemical solution, and even if the ejection of the drug solution was observed, it was extremely small. And the plug body 9 and the mouth plug body 8
Since the pressure of the balloon 3 does not reach the space between them, when the injection needle is pulled out from the mouth stopper 8, there is no pressure that would cause the drug solution to be squirted out, and therefore the drug solution does not flow outside the mouth stopper 8. Since there is no leakage, the injection operation of the chemical solution can be performed safely.

The check valve prevents the flow of medical fluid from the balloon 3 toward the mouth plug 8.

The one in Figure 3 is of the so-called Duckbill type, and the closed end of the valve has a pointed shape like the beak of a platypus, and in the case of this type of check valve 19, its valve body 17 or the support body 18 that supports the valve body 17, there is a means for allowing the permeation of the chemical liquid, albeit a small amount, for example, on the valve body 17 or the support body 18.
There are formed fine holes and grooves that create a small distance between the support body 18 and the valve body 17. On the other hand, in the check valve 29 shown in FIG.
The balloon 3 is pressed against the balloon 3 to prevent the medical solution from being discharged from the balloon 3. Porous glass, sintered metals, polymer sintered bodies, etc. can be used as materials for forming the filter, and metals that are commonly sintered include iron, stainless steel, molybdenum,
Polypropylene, polyethylene, etc. are used as the polymer to be sintered, such as brass. Further, the check valve 39 shown in FIG. 5 is a so-called umbrella type check valve, and the valve body 37 is shaped like an umbrella.
The support body 38 that supports the valve body 37 is formed using a porous filter similar to the valve body 27 of the check valve 29 shown in FIG. In the case of a check valve that uses a porous filter for the valve body and/or support body as shown in FIGS. 4 and 5, the chemical solution does not spray out and slowly permeates into the mouth plug body 8 side. Not only that, but even if particulate foreign matter is contained in the medicinal solution, it will be filtered out by the filter, so there is no chance of the foreign matter being accidentally injected into the human body. In addition, when a check valve is used as a means to obstruct the discharge of the drug solution, when the drug solution is injected into the balloon 3 with a syringe or the like, even if the injection operation is stopped midway through, the drug solution will not be subject to back pressure. You won't receive it and be pushed back.

Next, a method of using the liquid drug injection device of the present invention will be described with reference to the case of the injection device shown in FIG. 2.

The drug solution is injected by inserting a syringe needle (not shown) from the mouth plug 8 side and penetrating the mouth plug 8 and the inner plug 9 with the needle. As the balloon 3 is filled with the medical solution, it expands not only in the radial direction but also in the axial direction. When a predetermined amount of the drug solution has been filled, the injection needle is removed from the stoppers 8 and 9. Next, the liquid guide needle 13 of the flow rate control section C is inserted from the mouth plug 8 side, and penetrates the mouth plug 8 and the inner plug 9. At this time, it is necessary to keep the mini clamp 14 in a closed state so that the chemical solution does not flow out toward the tube D.

After that, connect the connector E according to the actual chemical injection point.
The catheter is connected to an intravenous catheter or a balloon catheter having a winged needle through the catheter, and after predetermined operations such as air bleeding are performed, the medicinal solution is injected into the patient's body.

It should be noted that, since the drug solution injection tool of the present invention is characterized by the drug solution passage 7 portion, a detailed explanation of the portion other than the drug solution passage 7 portion will be omitted.

〔Effect of the invention〕

As explained above, the drug solution injection device of the present invention has the following advantages in addition to the effects of the drug solution injection device previously proposed by the applicant: (1) After the drug solution is press-fitted into the rubber-like elastic container, the injection needle When the drug is removed from the mouth stopper, the medicinal solution will not leak out of the mouth stopper.
Operators are not exposed to dangerous drugs such as anti-cancer drugs.

(2) If a stopper is also provided on the inside, there is less loss of drug yield and it is economical.

(3) When a check valve using a porous filter is provided inside, foreign substances such as fine particles in the chemical solution are filtered out, so foreign substances are not accidentally injected into the human body, and it is safe.

[Brief explanation of the drawing]

FIG. 1 is a plan view of one embodiment of the drug injection tool of the present invention, showing a state in which the liquid guide needle is not inserted into the stopper, and FIG. 2 is a balloon portion of the injection tool shown in FIG. 1. FIGS. 3 to 6 are enlarged sectional views of main parts in other embodiments. Moreover, FIG. 6 is a plan view showing an example of a conventional chemical liquid injection tool. [Explanation of main symbols], I: Liquid injection tool, A:
Balloon part, B: Housing, C: Flow rate control part,
D: Chemical injection tube, E: Connector, 1: Outer shaft,
2: Inner shaft, 3: Balloon, 7: Chemical liquid passage, 8: Mouth stopper, 9: Inner stopper, 19, 29, 39: Check valve.

Claims (1)

[Scope of Claims] 1. A drug solution is press-fitted into an easily inflatable container made of a rubber-like elastic material, and the drug solution press-fitted into the container is discharged using the contracting force of the expanded container. In the device for injecting into the body, the container has a common passage for injecting and discharging the drug solution, and the common drug solution channel has an opening made of a rubber-like elastic material through which a syringe needle can be inserted. 1. A drug solution injection device, characterized in that it is liquid-tightly sealed by a stopper, and a means for obstructing discharge of the drug solution is provided in a drug solution passage portion inside the stopper. 2. The means for obstructing the ejection of the drug solution is a stopper made of a rubber-like elastic material that can be penetrated by a syringe needle, and the injection and ejection of the drug solution are performed by the syringe needle inserted into the two stoppers of the drug solution passage. The drug solution injection device according to claim 1, which is used for injection. 3. The means for obstructing the discharge of the chemical solution is a check valve,
2. The drug solution injection device according to claim 1, wherein the check valve is configured to allow slight leakage from the valve body or a support portion that supports the valve body. 4. The valve body of the check valve is formed of a filter made of a sintered body of polymer powder or a sintered body of metal powder, and the valve body suppresses rapid discharge of the chemical liquid from the container and prevents the liquid from entering the chemical liquid. 2. The liquid drug injection device according to claim 1, wherein fine particles and the like are filtered out. 5. A claim in which the check valve is composed of a membrane-like valve body made of a rubber-like elastic material and its support, and at least a part of the support is formed of a filter made of a sintered body of polymer powder or metal powder. 1. The liquid drug injection tool according to 1.