JPH05229904A - Disinfectant for pierced earring - Google Patents

Abstract

PURPOSE:To obtain the subject low-irritant disinfectant with stability and medici nal virtues secured, staying at local sites for a long time even in the case of its low application by formulating a non-ethanol-based benzalkonium chloride at low concentration as the chief ingredient with a thickening agent, solubilizing agent, preservative, etc., into a gel-like form. CONSTITUTION:The objective disinfectant can be obtained by formulating (A) benzalkonium chloride as the chief ingredient with (B) a thickening agent such as hydroxyethyl cellulose, (C) a solubilizing agent such as 1,3-butylene glycol, (D) a preservative such as methylparaben or benzoic acid, etc. This disinfectant, because of its gel-like form, stays at local sites for at least half a day or so in a single application, promising secured disinfecting effect in application twice a day. Besides, this disinfectant are completely free alcohols; and therefore irritant to injured skin, thus promising disinfecting effect.

Description

Detailed Description of the Invention

[0001]

FIELD OF THE INVENTION The present invention relates to a sterilizing disinfectant,
Specifically, a small hole is made in the ear lobe (hereinafter referred to as piercing) in order to put on a pierced earring (hereinafter referred to as piercing), but piercing dermatitis may occur until the small hole is completed. Disinfectant that protects and disinfects the skin to prevent

[0002]

[Prior Art] Earrings are still popular in Japan during the Kofun period, but since Buddhism and Confucianism were introduced from China, their habits have gradually diminished and most people do not use earrings until recently. did not exist. On the other hand, earrings are very popular ornaments in foreign countries, mainly in Europe, America and the Middle East,
More than 95% of women in the United States are said to have pierced piercing holes. Due to western lifestyles in recent years, the piercing epidemic has begun in Japan, and the number of piercing enthusiasts is rapidly increasing not only among young women but also among men.

[0003] However, piercing means artificially injuring a healthy ear lobe, and completion of an ostium means healing (epithelialization) of the wound without purulence. About 1 from piercing to completion of epithelialization
It is said that it takes months, and disinfection and treatment during that period are very important. However, in Japan, the history of piercing is short, and at accessory stores and jewelry stores that sell piercings, there is a tendency to easily recommend piercing, so complications such as contact dermatitis, cellulitis, and nodule formation (hereinafter, The rapid increase in the number of patients who suffer from pierce dermatitis has become commonplace in academic societies and the media.

[0004] In order to prevent piercing dermatitis, the quality of the piercing to be worn first is important, and at the same time, the disinfection control after piercing is very important. At the heart of its aftercare is the use of good quality disinfectants. Generally, the most familiar disinfectant is ethanol for disinfection, and it seems that many doctors and pharmacists actually recommend ethanol. In Europe and America, there are several kinds of gel-like disinfectants, all of which contain alcohol.

[0005]

The above-mentioned disinfectant ethanol is for disinfecting the skin of the surgical field (that is, suitable for disinfecting ear lobe before piercing), and disinfecting damaged skin immediately after piercing. Contraindicated due to its stimulating effect. In addition, since ethanol dries immediately after application, a large amount of ethanol is applied to the entire ear lobe frequently and in a wide area except around the small holes. Furthermore, it is said that it is necessary to be careful because repeated use at the same site may cause skin roughness due to degreasing and the like, and it is not appropriate to use ethanol as a disinfectant after piercing.

[0006] Topical dryness is one of the factors that impairs wound healing, and attention must be paid to prevent dryness of the wound. Therefore, generally, it is often practiced to disinfect the damaged skin, apply an appropriate ointment, and cover the wound with gauze or the like to treat the wound. However, in the case of piercing, one month is required even if it goes smoothly, and during that time, it can be said that the wound remains open without being covered with gauze or the like, and tends to be easily dried.

Therefore, the present invention has been made in view of the problems of the above-mentioned conventional techniques. The purpose of the present invention is to secure stability as a drug and efficacy without using alcohol, and The purpose of the present invention is to provide a hypoallergenic antiseptic for piercings that can be applied locally for a long time.

[0008]

[Means for Solving the Problems] The technical means taken by the present invention to achieve the above-mentioned object is a non-ethanol type low concentration benzalkonium chloride as a main component, and a thickener, It is characterized in that it is made into a gel by adding a solubilizer, a preservative and the like. Examples of the thickening agent that gels benzalkonium chloride as a main component include hydroxyethyl cellulose, examples of the solubilizing agent include 1.3 butylene glycol, and methyl paraben as a preservative.
Examples thereof include sodium benzoate. The disinfectant may be a cloudy opaque liquid or a colorless transparent liquid, but a coloring agent is added to make it a colored transparent liquid, for example, a pink transparent liquid, because many women in the age group who wear piercings are young. Of course it is possible.

[0009]

Since the disinfectant for pierce having the above-mentioned constitution is in the form of gel, it is considered that the disinfectant effect can be expected by applying it once and staying locally for about half a day.
And since this disinfectant contains no alcohol at all,
The disinfectant effect can be expected without irritation to the damaged skin.

[0010]

EXAMPLES Examples of the present invention will be shown below, but the present invention is not limited thereto. [Example 1] The components of the formulation liquid are as follows. Benzalkonium chloride 50% liquid 0.1 Hydroxyethyl cellulose (thickener) 2 Methylparaben (preservative) 1 Sodium benzoate (preservative) 9.15 1.3 Butylene glycol (solubilizer) 4 Aloe extract 1 Glycerin 6 Red No. 106 (0.25%) Liquid) (Colorant) 0.06 Purified water Suitable amount

The disinfectant shown in the above-mentioned Example 1 is a gel of pink emulsion, and discoloration and abnormality in PH were not observed in the accelerated test. Tables 1 and 2 show the results of the accelerated test for one month and two months. [Discussion] The disinfectant of Example 1 described above is a weakly acidic liquid.
Although a slight change in PH is recognized by the acceleration test, there is no change in appearance in the pink emulsion. However, although it is a transparent liquid in a heated state of 40 ° C. and 60 ° C., it becomes an opaque liquid at a liquid temperature of 20 ° C.

The results of the antibacterial activity test of Example 1 described above are shown in Table 3. [Discussion] The blocking circle of Example 1 was as large as 24 mm, while the blocking circle of 0.05% benzalkonium chloride solution was 17 mm. Therefore, it is considered that the antibacterial activity exerts a synergistic effect by the influence of other agents.

In addition, 19.5 ml of the above-mentioned formulation solution of Example 1 was placed in a test tube, and 0.5 ml of 10 ⁴ bacterial solution of pure water was cultured in the test tube.
After adding well and stirring well, put it in a thermostat at 25 ° C and incubate. Then, 1 week, 2 weeks, 3 weeks later, 1 ml was sampled, the number of bacteria was measured, and the antifungal effect of the prescription liquid was confirmed. In the latter case, the number was 0, and in the case after 3 weeks, the number was 0, and it is considered that the bacteria were killed by the action of the drug.

[0014]

EFFECTS OF THE INVENTION Since the piercing disinfectant of the present invention is constructed as described above, it is a disinfectant that does not cause irritation to damaged skin and can stay locally for a long time even with a small amount of application, and can maintain the disinfecting effect. Agents can be provided.

Claims (1)

[Claims] 1. A disinfectant for pierce, which comprises benzalkonium chloride as a main component and which is mixed with a thickener, a solubilizer, an antiseptic and the like to form a gel.