JPH05192090A - Method for feeding vitamin b group to monogastric animals - Google Patents

Abstract

(57) [Summary] [Objective] To provide a method of feeding a vitamin B group to a monogastric animal such as a pig or a broiler for the purpose of reducing the body fat content. [Composition] Riboflamin (vitamin B2) belonging to the B vitamin group, nicotinic acid amide, and biotin were fortified in the feed, and due to the biochemical characteristics of nutrients, feed intake, body weight gain, and body protein It specifically reduces body fat content without affecting its content.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a vitamin B group feeding method for feeding a monogastric animal such as a pig or a broiler with a vitamin B group for the purpose of reducing body fat content. ..

[0002]

2. Description of the Related Art In recent years, excessive accumulation of fat in pigs and broilers has become an important issue that needs urgent solution. On the other hand, according to the recent Japanese National Nutrition Survey, the amount of fat intake of Japanese people has been increasing year by year.
More than one-third is occupied by animal fat. Since excessive intake of fats, especially animal fats, is a factor promoting hyperlipidemia and arteriosclerosis, it is desired to suppress the intake thereof.

[0003]

The amount of feed consumed for fat accumulation in pigs and broilers as described above requires about four times the amount of accumulated fat, which is necessary for the production of extra fat. Much of the feed is wasted. Against this background, if it is possible to reduce the amount of fat accumulated without suppressing the growth of livestock, it is possible to reduce the waste of the feed wasted for the production of excess fat and to improve the efficiency of meat production. At the same time, it has important significance for humans, such as preventing excessive fat intake. Conventionally, in order to achieve this object, quality and amount of feed, improvement of livestock breeding, utilization of β-adrenergic agonists (β-agonists) such as cimaterol and clenbuterol, growth hormone, and antibody administration to adipocytes Consideration is being made from the aspect. Unlike the conventional method, the present invention specifically reduces the body fat content by utilizing the biochemical properties of nutrients without affecting the feed intake, the weight gain and the body protein content. It was made for that purpose.

[0004]

[Means for Solving the Problems] In order to achieve the above object, the present invention uses three kinds of riboflamin (vitamin B2) belonging to the vitamin B group, nicotinic acid amide and biotin in order to reduce the body fat content. Characterized by fortification in feed.

[0005]

By the above means, the present invention utilizes the biochemical characteristics of nutrients by fortifying the diet with vitamins belonging to the three B-vitamin groups, thereby utilizing feed intake, weight gain and body The body fat content can be specifically reduced without affecting the protein content.

[0006]

[Examples] Many enzymes in the animal body require the participation of coenzymes in order to exhibit their activities, and many vitamins belonging to the vitamin B group are constituent components of various coenzymes, such as hydrogen, carbon dioxide, It has a biochemical property of transferring an aldehyde, an acyl group, a formyl group and the like to a substrate or receiving it from the substrate, and plays an important role in the metabolism of nutrients. In addition, the B vitamins are water soluble,
Even if ingested in a large amount to some extent, it is excreted out of the body relatively quickly, so that it has a property that its harmful effect is difficult to appear.

From the above viewpoints, the vitamin B group was taken up as a method for controlling lipid metabolism, and research was conducted according to the following procedure. Eight kinds of vitamins belonging to the B-vitamin group were individually added to several levels of each diet, and the rats were sacrificed after being fed to the rats for a certain period of time, and carcasses were analyzed, without lowering feed intake, weight gain and body protein content. , We squeezed vitamins that are effective for specifically reducing body fat content. Next, the combination effect was examined for the plurality of vitamins squeezed as described above, and the combination method of vitamins in which the decrease in body fat content was further enhanced was examined.

From the above studies, three types of riboflavin (vitamin B2), nicotinic acid amide and biotin were selected as the only effective vitamins for reducing body fat content. Further, it was found from the above-mentioned study that the maximum reduction in body fat content was observed when riboflavin (vitamin B2), nicotinic acid amide and biotin were simultaneously added to the feed. Furthermore, as a result of performing additional tests on this test result, it was confirmed that there is reproducibility,
The present invention has been completed.

Next, the contents of the present invention will be described in more detail with reference to experimental examples. [Experimental Example 1] (1) Test method A control feed mainly containing corn, soybean meal and fish meal so as to sufficiently contain nutrients necessary for rat growth, and riboflavin (vitamin B2) 0.07 in this feed.
5%, nicotinamide 0.5% or biotin 0.0
About 5% of any one of the total 5 kinds of feeds (see Table 1) to which 2 or 3 kinds were added externally was added.
Og male Wistar rats were fed and sacrificed on day 28 and carcass analysis was performed on these rats.

(2) Test Results The results of Experimental Example 1 are shown in Table 1. From Table 1, riboflavin (vitamin B2) 0.075% and nicotinic acid amide 0.5% were added externally to the feed, and 2 groups, and nicotinic acid amide 0.5% and biotin 0.05% were added to the feed. In addition, in the 4 groups added, the body fat content is reduced by about 2.5% compared to the 1 group (control group), but riboflavin (vitamin B
2) The body fat content of the 5th group in which three kinds of 0.075%, 0.5% of nicotinic acid amide and 0.05% of biotin were externally added to the feed was higher than that of the 1st group (control group). It dropped by 9%. However, riboflavin (vitamin B2) 0.07
In the 3 groups to which 5% and biotin 0.05% were added externally, the body fat content in the 1 group (control group) tended to increase somewhat.

From the above, the addition of riboflavin (vitamin B2), nicotinic acid amide and biotin at the prescribed levels to the feed significantly reduced the body fat content compared to the control group. It was discovered. Further, in this case, although the feed intake, the weight gain, the body protein content, and the ash content of the body were not different from those of the control group, the body water content was increased. From this, although the above three vitamins were added to the feed at the same time, the body fat content was reduced,
The reason why the increase in body weight was not inferior to that in the control group was that it was mainly due to the increase in body water content.

[Experimental Example 2] (1) Test Method In Experimental Example 2, an additional test was conducted in order to confirm the knowledge found in the 5 groups of Experimental Example 1. Weight at the beginning of the experiment is about 18
Using 0 g of male Wistar rats, fed a high-nutrition feed consisting mainly of cereals 46% and animal feed 32% 1
Two groups (control group) and two groups (test group) in which riboflavin (vitamin B2) 0.075%, nicotinic acid amide 0.5% and biotin 0.05% were externally added to this feed. It was installed (see Table 2) and tested for 29 days. After the end of the test, these rats were sacrificed and subjected to carcass analysis.

(2) Test Results The results of Experimental Example 2 are shown in Table 2. As shown in Table 2, feed intake and body weight gain were 1 group (control group).
No difference was observed between the 2nd plot and the 2nd plot (test plot). Regarding the composition of body components, however, the water content in the 2 groups (test group) fortified with 3 vitamins increased by 3.8% compared to 1 group (control group), and conversely, the body fat content was 4. A 4% reduction was observed. Also, in this case, the body protein content showed a tendency to increase to some extent, and the body ash content was 1
No difference was observed between the plot (control plot) and the plot 2 (test plot). The above-mentioned results of Experimental Example 2 indicate that the body fat content is remarkably reduced by fortifying the diet with the three types of riboflavin (vitamin B2), nicotinic acid amide and biotin observed in Experimental Example 1. It was supported and confirmed to be reproducible.

[Comparison with reduction of body fat content compared with the case of administration of other substances] Clenbuterol, which is one of β-adrenergic agonists (β-agonists) which has been recently studied in order to reduce body fat content Was added to the rat diet (Abe, H. and Saitoh,
M. , Jpn. J. Zoote-ch. Sci. , 5
9: 446-454, 1988) and in the case of antibody administration to rat adipocytes (Paton, D. et a.
l. , Am. J. Phys-iol. , 258: E98
5-E989, 1990) and the effects on the reduction of body fat content were compared with the effects on the reduction of body fat in the case of adding the above-mentioned three vitamins according to the present invention. To compare the effects on the reduction of body fat content, the ratio of reduction of body fat content by administration or addition of each substance to the control group was determined and investigated. The results are shown in Table 3.

From the results of Table 3, vitamin 3 according to the present invention
The reduction rate of the body fat content when the seeds (riboflavin, nicotinic acid amide and biotin) were added to the feed was measured in Experimental Example 1
The average of 2 and 2 was 25.6%, which is about 45% higher than 17.7% of simaterol administration, and it has an effect almost equal to 24.4% of antibody administration to adipocytes. Was regarded When comprehensively judged from the above experimental results, by fortifying three kinds of vitamins belonging to the B vitamin group of the present invention in the feed, the feed intake, the weight gain and the body protein content were not reduced. It was found that it is possible to effectively reduce the body fat content.

[0016]

As described above, according to the method for feeding a group of vitamins B to a monogastric animal of the present invention, as is clear from the experimental results, riboflavin (vitamin B).
2) It was possible to effectively reduce the body fat content by fortifying nicotinic acid amide and biotin at a predetermined level in the feed. By applying the present invention, it becomes possible to produce livestock meat having a low fat content, the efficiency of meat production is improved, and it is possible to contribute to the health promotion of humans who ingest these as meat. In recent years,
Obesity (fat excess accumulation) in the case of people who are particularly at issue
There is potential for application in the therapeutic aspect of As described above, the present invention has great significance in terms of industrial use.

[Table 1]

[Table 2]

[Table 3]

Claims (1)

[Claims] 1. A method for feeding a group of vitamins B to a monogastric animal, characterized in that riboflamin (vitamin B2) belonging to the group of vitamins B, nicotinamide and biotin are fortified in a feed.