JPH05142222A - Chromatograph data processor - Google Patents

Abstract

(57) [Abstract] [Purpose] To provide a data processing device for a chromatograph that performs an appropriate automatic analysis that matches the actual operating environment of the device. [Configuration] A data processing device for a chromatograph, which has a sample table in which a series of automatic analysis procedures are described, and which performs automatic analysis processing according to the description of the sample table, and which receives the actual operating environment of the chromatograph device. Environment input processing (ST2), analysis condition input processing (ST3) that reads the analysis conditions from the analysis condition file, the device environment that enables the analysis, and the initial setting conditions for operating each device, and ST2 Compare the received device operating environment with the device environment read in ST3,
An analysis selection process (ST4 to ST7) for automatically analyzing only items that meet the conditions is provided.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a data processing device for a chromatograph, and more particularly to a data processing device for performing automatic analysis according to the description of a sample table.

[0002]

2. Description of the Related Art Conventional chromatograph data processing apparatuses generally perform automatic analysis as follows.
That is, analysis conditions and device parameters are determined for each sample, and a plurality of these are prepared as analysis condition files.On the other hand, in the sample table, in addition to the sample name to be measured and the amount of the sample, the above Describe which analysis condition file is used for analysis.

Then, based on the description of the sample table, the analysis condition file is appropriately changed for each sample to automatically analyze the data.

[0004]

However, the above-mentioned analysis condition file does not describe the apparatus environment that enables the analysis. Therefore, if the specified contents of the analysis condition file do not match the operating environment of the device that is actually operating, the analysis operation will be performed on a device that does not exist, or random analysis will be performed. There is a problem.

The present invention has been made in view of this problem, and an object of the present invention is to provide a data processing device for a chromatograph which performs an appropriate automatic data analysis suitable for an actual operating environment of the device. ..

[0006]

In order to achieve the above object, a chromatographic data processing device according to the present invention is provided with a series of automatic analysis procedures such as vial number, sample name, sample amount, analysis condition file name. Having a sample table described for each sample, which is a chromatographic data processing device for performing automatic analysis processing according to the description of the sample table, a device environment input means for receiving the actual device operating environment of the chromatograph, An analysis condition input means for reading the contents of the analysis condition file which describes the analysis condition, the device environment enabling the analysis, and the initial setting condition for operating each device, and By comparing the device environment read by the analysis condition input means with the actual device operating environment received by the device environment input means, Has characteristically an analysis selection means for automatic analysis only match items.

[0007]

The chromatograph data processing apparatus according to the present invention is an apparatus for appropriately performing automatic data analysis in accordance with the description of the sample table created by the user. When the user instructs to start the automatic analysis after creating the sample table, the device environment input means first receives the actual device operating environment. Here, the device operating environment refers to, for example, data indicating the device name of the currently connected LC (liquid chromatogram device), the setting state of the pump, the autosampler, the degasser, and the like.

Next, the analysis condition input means reads the contents of the analysis condition file. The analysis selecting means judges whether or not the device environment described in the analysis condition file matches the device operating environment currently constructed. Suspend. On the other hand, if the currently established device operating environment is not perfect but can be analyzed, automatic analysis is performed only for the range that is possible in the current device operating environment.

[0009]

The present invention will be described in more detail based on the following examples. FIG. 1 is a schematic block diagram of a chromatographic data processing device according to an embodiment of the present invention. This apparatus receives an apparatus operating environment from the analysis apparatus 1 side, performs an appropriate automatic analysis, an apparatus main body 2, an external storage device 3 for storing an analysis file, and the like.
The keyboard 4 is used for creating a sample table and the like, and the CRT 5 for displaying analysis results and the like.

As the analyzer 1, for example, a solvent 6 and
Pump 7, autosampler 8, LC 9, and detector 1
0, the waste liquid processing unit 11, and the communication device 12 or the like that transmits the detection data of the detector 10 to the data processing device main body 2 are conceivable. As described above, this chromatograph data processing device is a device that performs automatic analysis according to the description of the “sample table” created by the user, and stores the contents of the “analysis condition file” stored in the external storage device 3. This is a data processing device that reads each sample and performs appropriate automatic analysis.

Here, in each row of the "sample table", in addition to the vial number (the number of the bottle containing the sample), the sample name, the amount of the sample, etc., various conditions for the analysis are defined. The file name of "file" is described. The “analysis condition file” defines the analysis conditions, the device environment, and the device parameters. For example, (i) how to quantify, (ii) how to make a calibration curve, and (iii) data in the column of analysis conditions. The file name, (iv) raw chromatographic file name, (v) how to output the report, etc. are set. It should be noted that (ii) how to make a calibration curve refers to commands such as at what point data is created, how an average value is obtained, and whether the calibration curve is a graph by the least squares method or a line graph.

The environment of the equipment which enables the above-mentioned analysis is set in the equipment environment column, and what kind of equipment is combined, for example, an autosampler, a pump, a liquid chromatogram equipment (LC), and a detection equipment. What to use as a container is specified. In addition, in the device parameter column, initial setting conditions for operating the device are described, and for example, for operating the autosampler normally specified in the device environment column, for the autosampler control device, Data (Move xcm in X direction,
Data that the needle comes to the position of the sample bottle when it is moved down ymm in the Y direction and then moved down zmm) is described.

Based on the above points, the operation of the chromatographic data processing device 2 shown in FIG. 1 will be described. 2 is a flowchart for explaining the operation of the data processing device 2, and FIG. 3 is a drawing schematically showing the contents of the memory of the data processing device 2. In FIG.
The device status storage unit 20 stores the device operating environment from the analyzer 1, and the analysis condition storage unit 21 expands the contents of the analysis condition file by the number of analysis samples, and the upper and lower limit check data unit 22. In, the data of the "upper and lower limit value file" is expanded. Further, the sample table 23 is created using the keyboard 4 or the like, and the simulation routine 24 performs the following processing shown in FIG.
(See FIGS. 2 and 3).

After the user creates the sample table,
When the start of the automatic analysis process is instructed, the operation of the data processing device 2 is started (step ST (hereinafter abbreviated as ST)).
1), the data processing device 2 acquires data indicating the actual device operating environment from the analysis device 1 side and stores it in the device state storage unit 20 (ST2). Specifically, for example,
Data indicating the types of currently connected autosamplers, pumps, LCs, detectors, the power ON / OFF state, the size of syringes of the autosampler, the size of racks, and the like are acquired.

Next, the data processing device 2 reads the analysis condition for one sample from the corresponding analysis condition file into the analysis condition storage unit 21 based on the description of the sample table 23 (ST3). Here, as a specific example, in the device environment column of the analysis condition file, the auto sampler is A,
Pump is B, liquid chromatogram device is C, detector is U
It is stated that a V detector and an RF detector are used.

Subsequently, the data processing device 2 receives the device operating environment stored in the device state storage section 20 in the process of ST2 and S
The consistency of the analysis conditions stored in the analysis condition storage unit 21 in the process of T3 is checked (ST4). Specifically, the column of the device environment of the analysis condition storage unit 21 is compared with the actual device operating environment, and if it does not match the device environment at all and cannot withstand the analysis, the process is interrupted. On the other hand, if the device environment is provisionally prepared, the process proceeds to the next step ST5.

In ST5, the "upper / lower limit value file" that matches the apparatus environment read in the process of ST3 is read from the external storage device 3 and stored in the upper / lower limit value checking data section 22 (ST5). In other words, the upper and lower limits of the operation of each device corresponding to the above device environment (A for autosampler, B for pump, C for liquid chromatogram device, VV detector and RF detector for detector) are described. The upper and lower limit value file is read (ST5).

Then, the values described in the sample table are
It is determined whether or not it is included in the range of the upper and lower limits (ST6). More specifically, for example, in the upper and lower limit value file, the sample injection amount of the autosampler A is 0 ml to 20 ml.
If it is 00 ml, it is judged whether or not the amount of the sample described in the sample table is within the range of the upper and lower limit values.
If there are too many samples in the sample table, the fact is displayed on the CRT 5 and the mode is returned to the sample table creation mode (ST6).

By the way, although the apparatus environment is compared in the processing of ST4, even if the apparatus environments do not completely match, the processing of ST4 to ST5 may be followed by the processing of ST7. However, in that case, only the part where the environment matches is analyzed (ST7). For example, it is stated that the UV detector and the RF detector are used in the column of the equipment environment in the analysis file, while the actual equipment environment is such that the UV detector is turned off. If so, only the data of the RF detector will be analyzed thereafter. Therefore, no analysis operation is performed on a device that does not exist.

Then, the processes of ST3 to ST7 are repeated according to the sample table until the automatic analysis is completed (ST8).

[0021]

As described above, in the chromatographic data processing device according to the present invention, since the device environment is described in the analysis condition file, it is determined whether or not it matches the actual device operating environment. It is possible to take necessary measures according to the judgment result. That is, the analyzer does not malfunction, and it is not necessary to interrupt the analysis unnecessarily.

Even if the device environment described in the analysis condition file and the actual device environment do not completely match, only the matching part can be analyzed. No need to rewrite.

[Brief description of drawings]

FIG. 1 is a schematic block diagram of a chromatographic data processing device according to an embodiment of the present invention.

FIG. 2 is a flow chart for explaining the operation of the apparatus of FIG.

3 illustrates the memory contents when the device of FIG. 1 operates.

[Explanation of symbols]

 ST2 Device environment input means ST3 Analysis condition input means ST4 to ST7 Analysis selection means

Claims (1)

[Claims] 1. A sample table in which a series of automatic analysis procedures such as vial number, sample name, sample amount, and analysis condition file name are described for each sample, and automatic analysis processing is performed according to the description of this sample table. A data processing device for a chromatograph, which receives the actual device operating environment of the chromatograph, the device environment input means, the analysis conditions, the device environment that enables the analysis, and the initial settings for operating each device. From the analysis condition file describing the conditions, the analysis condition input means for reading the contents of the file, the device environment read by the analysis condition input means, and the actual device operating environment received by the device environment input means And a selection means for performing automatic analysis only on items that meet the conditions. Off for data processing equipment.