JPH05115547A - Monitoring device for blood flow state in shunt forming part - Google Patents
Monitoring device for blood flow state in shunt forming partInfo
- Publication number
- JPH05115547A JPH05115547A JP3309896A JP30989691A JPH05115547A JP H05115547 A JPH05115547 A JP H05115547A JP 3309896 A JP3309896 A JP 3309896A JP 30989691 A JP30989691 A JP 30989691A JP H05115547 A JPH05115547 A JP H05115547A
- Authority
- JP
- Japan
- Prior art keywords
- shunt
- blood
- microphone
- blood flow
- sound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000017531 blood circulation Effects 0.000 title claims abstract description 27
- 238000012806 monitoring device Methods 0.000 title description 4
- 239000008280 blood Substances 0.000 claims abstract description 18
- 210000004369 blood Anatomy 0.000 claims abstract description 18
- 238000001514 detection method Methods 0.000 claims abstract description 13
- 230000006866 deterioration Effects 0.000 claims abstract description 6
- 230000015572 biosynthetic process Effects 0.000 claims description 15
- 230000004087 circulation Effects 0.000 claims description 8
- 230000007423 decrease Effects 0.000 claims description 3
- 238000012544 monitoring process Methods 0.000 claims 1
- 208000007536 Thrombosis Diseases 0.000 abstract description 8
- 210000000707 wrist Anatomy 0.000 abstract description 3
- 210000003462 vein Anatomy 0.000 description 8
- 238000002555 auscultation Methods 0.000 description 6
- 210000001367 artery Anatomy 0.000 description 5
- 239000003527 fibrinolytic agent Substances 0.000 description 5
- 229960000103 thrombolytic agent Drugs 0.000 description 5
- 230000023555 blood coagulation Effects 0.000 description 4
- 238000001356 surgical procedure Methods 0.000 description 4
- 230000009471 action Effects 0.000 description 3
- 210000004204 blood vessel Anatomy 0.000 description 3
- 230000003203 everyday effect Effects 0.000 description 3
- 238000001914 filtration Methods 0.000 description 3
- 238000001631 haemodialysis Methods 0.000 description 3
- 230000000322 hemodialysis Effects 0.000 description 3
- 238000000746 purification Methods 0.000 description 3
- 238000002560 therapeutic procedure Methods 0.000 description 3
- 230000005856 abnormality Effects 0.000 description 2
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 239000003146 anticoagulant agent Substances 0.000 description 2
- 229940127219 anticoagulant drug Drugs 0.000 description 2
- 239000003130 blood coagulation factor inhibitor Substances 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 241001631457 Cannula Species 0.000 description 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
- 102000013566 Plasminogen Human genes 0.000 description 1
- 108010051456 Plasminogen Proteins 0.000 description 1
- 208000001647 Renal Insufficiency Diseases 0.000 description 1
- 102000003990 Urokinase-type plasminogen activator Human genes 0.000 description 1
- 108090000435 Urokinase-type plasminogen activator Proteins 0.000 description 1
- 239000012190 activator Substances 0.000 description 1
- 230000004397 blinking Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000004020 conductor Substances 0.000 description 1
- 238000000502 dialysis Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 229960002897 heparin Drugs 0.000 description 1
- 229920000669 heparin Polymers 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 201000006370 kidney failure Diseases 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 230000003908 liver function Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 210000000689 upper leg Anatomy 0.000 description 1
- 229960005356 urokinase Drugs 0.000 description 1
- 230000002618 waking effect Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Landscapes
- External Artificial Organs (AREA)
Abstract
Description
【０００１】[0001]
【技術分野】本発明は、人工臓器を用いた血液透析乃至
は濾過療法において、生体からの血液の取出部位となる
シャント形成部位における血液の流通状態をモニターす
ることにより、同部位における血栓の発生を早期に発見
するためのモニター装置に関する。TECHNICAL FIELD The present invention, in hemodialysis or filtration therapy using an artificial organ, monitors the circulation state of blood at a shunt formation site, which is a site for extracting blood from a living body, to thereby generate a thrombus at the site. The present invention relates to a monitor device for early detection.
【０００２】[0002]
【背景技術】近年、一旦体外に取り出した生体の血液
を、半透膜を収容した函体内に流通せしめて、該半透膜
を介しての透析作用や濾過作用により、かかる血液に対
して所定の浄化作用を施し、更には除水により、その量
的調節を行なった後、再び生体内に戻すことによって、
腎機能や肝機能が人工的に奏せしめられるようにした、
所謂人工臓器を用いた血液浄化療法が、一般に採用され
てきており、その顕著な効果が認められている。例え
ば、腎不全患者に対して適用される、所謂人工腎臓を用
いた血液透析乃至は濾過療法は、その代表的なものであ
る。BACKGROUND ART In recent years, blood of a living body once taken out of the body is circulated in a box containing a semipermeable membrane, and dialysis action or filtration action through the semipermeable membrane causes a predetermined amount to be applied to the blood. By performing the purification action of, and further by removing the water, after adjusting the quantity, by returning to the living body again,
I made it possible to artificially perform renal function and liver function,
Blood purification therapy using so-called artificial organs has been generally adopted, and its remarkable effect has been recognized. For example, hemodialysis or filtration therapy using a so-called artificial kidney, which is applied to patients with renal failure, is a typical one.
【０００３】ところで、人工腎臓によって血液浄化を行
なうに際しては、体外循環に必要な血流量を確保するた
めに、所謂シャントと呼ばれる手術が為されることとな
り、腕部や大腿部等に外シャント若しくは内シャントが
形成される。そのうち、外シャントは、よく知られてい
るように、例えば腕などの部位において、動脈及び静脈
のそれぞれに挿入された二本のカニューレを体外で連結
し、体外循環させるものである。一方、内シャントは、
例えば腕などの部位において、体表面側に位置する静脈
に、体の深部に位置する動脈のうちの一本を結合して、
バイパスさせ、静脈側の血流量を増加させるものであ
り、血液を体外へ取り出す場合には、シャント部分（動
脈化された静脈部分）に対して針を刺して、血液ポンプ
で引きながら行なう。このようにして、外シャント若し
くは内シャント形成部位より、血液を体外へ取り出すこ
とにより、体外循環に必要な２００〜８００ml／min 程
度の血流量が確保されている。By the way, when performing blood purification with an artificial kidney, a so-called shunt is operated in order to secure the blood flow necessary for extracorporeal circulation, and an external shunt is applied to the arm or thigh. Or an inner shunt is formed. As is well known, the outer shunt is a device for connecting two cannulas, which are inserted into an artery and a vein, to the outside of the body to circulate the body, for example, at a site such as an arm. On the other hand, the inner shunt is
For example, in a region such as an arm, one of the arteries located deep in the body is connected to a vein located on the body surface side,
This is to bypass and increase the blood flow on the venous side. When taking blood out of the body, the shunt portion (arterialized vein portion) is pierced with a needle and pulled by a blood pump. In this way, the blood is taken out of the body from the site where the outer shunt or the inner shunt is formed, so that a blood flow of about 200 to 800 ml / min necessary for extracorporeal circulation is secured.
【０００４】然るに、かかるシャント形成部位において
は、何等かの原因で、血液の凝固が惹起され易く、しば
しば、血栓が生じるという問題が発生する。そして、血
栓が生じた場合には、それが早期に発見されたならば、
血液凝固阻止剤や血栓溶解剤を投与して、生じた血栓を
溶かす等して、除去することができるが、時間が経過す
ると、最早、それを溶かすことが困難となるため、手術
によって血栓を除去しなければならなくなる。しかも、
この手術を数時間のうちに行なわなければ、その部分の
血管が使えなくなるため、改めて、もう少し心臓に近い
ところで、再度、シャントを形成しなければならないと
いった事態を招くこととなる。However, at such a shunt formation site, there is a problem that blood coagulation is apt to be caused for some reason and a thrombus often occurs. And if a blood clot occurs, if it is discovered early,
It can be removed by administering a blood coagulation inhibitor or a thrombolytic agent to dissolve the resulting thrombus, but over time, it will be difficult to dissolve it anymore. Will have to be removed. Moreover,
If this operation is not performed within a few hours, the blood vessels in that part will become unusable, which will lead to a situation in which a shunt must be formed again nearer to the heart.
【０００５】このため、従来から、患者は、毎日起床時
及び就寝時などにシャント音（シャント形成部位におけ
る血液の流動音）を聴診器で聞いて、血液の流通状態を
確認しているのであり、シャント音が小さくなって聞こ
えなくなったら、病院へ連絡し、直ちに血液凝固阻止剤
や血栓溶解剤の投与を受けたり、状況に応じて手術を受
けるようになっている。しかしながら、毎日、何度もシ
ャント音の確認をしなければならないことは、患者にと
って非常に面倒で、苦痛なものであり、また、患者がシ
ャント音の異常を発見した時には、通常、血液凝固阻止
剤や血栓溶解剤の投与により、シャント形成部位におけ
る血液の流通状態を回復させるには、既に手遅れであ
り、手術により、血栓を除去したり、或いはシャントを
再形成せざるを得ないのが現状である。For this reason, conventionally, a patient listens to a shunt sound (flowing sound of blood at the shunt formation site) with a stethoscope every day when waking up, going to bed, etc., to confirm the blood circulation state. If the shunt sound becomes too weak to hear, contact a hospital to receive anticoagulants or thrombolytic agents immediately, or to have surgery depending on the situation. However, having to check the shunt sound many times every day is very troublesome and painful for the patient, and when the patient discovers an abnormality in the shunt sound, it usually prevents blood coagulation. It is already too late to restore the blood circulation at the shunt formation site by the administration of an agent or thrombolytic agent, and the current situation is that surgery is required to remove the thrombus or recreate the shunt. Is.
【０００６】[0006]
【解決課題】本発明は、このような事情を背景として為
されたものであり、その解決課題とするところは、シャ
ント形成部位における血液の流通状態を、継続して自動
的に監視し得るようにして、患者の聴診の手間を軽減す
ると共に、血液の流通状態の悪化を早期に発見できるよ
うにすることにある。The present invention has been made in view of such circumstances, and a problem to be solved is to continuously and automatically monitor a blood circulation state at a shunt formation site. In addition, it is possible to reduce the trouble of auscultation of the patient and to detect the deterioration of the blood circulation state at an early stage.
【０００７】[0007]
【解決手段】そして、上記の課題を解決するため、本発
明にあっては、シャント形成部位に近接して配置され、
かかるシャント形成部位における血液の流通に対応した
シャント音を継続して検知するための少なくとも一つの
マイクロフォンと、血流状態の悪化によるシャント音の
低下に従って変化する該マイクロフォンにおける検出値
を、予め設定された下限値と比較するための判断回路
と、検出値が設定値を下回った場合に信号を発する制御
回路と、該制御回路の発した信号に基づいて作動せしめ
られる警報発生手段とを含んで構成されるシャント形成
部位における血流状態のモニター装置を、その要旨とす
るものである。In order to solve the above problems, in the present invention, the shunt forming portion is disposed in proximity to
At least one microphone for continuously detecting a shunt sound corresponding to the circulation of blood in the shunt formation site, and a detection value of the microphone that changes according to a decrease in the shunt sound due to the deterioration of the blood flow state are preset. And a lower limit value, a control circuit for issuing a signal when the detected value is lower than a set value, and an alarm generating means which is activated based on the signal issued by the control circuit. The gist of the invention is a monitoring device for the blood flow state at the shunt formation site.
【０００８】[0008]
【発明の効果】要するに、このようなモニター装置で
は、マイクロフォンによるシャント音の検知によって、
シャント形成部位の血流状態が継続して自動的に監視さ
れ得るのであり、シャント形成部位の血管が詰まりかけ
て、血流状態が悪化した場合には、シャント音の検出値
の変化に基づいて、警報発生手段が自動的に作動せしめ
られ、早期に患者に異状を知らせることができる。従っ
て、患者は血流状態を監視するために聴診を行なう必要
がなく、面倒な手間やその苦痛から完全に解放される。
そして、かかるモニター装置では、従来の聴診のように
血流状態の確認を忘れる心配がなく、また、数時間の間
隔をおいて行なわれる聴診と異なり、血栓の発生の発見
が遅れることがないため、安全性が高くなり、多くの場
合において、血液凝固阻止剤や血栓溶解剤等の投与によ
って血流状態を回復させることができ、手術に至る割合
を効果的に低減することが可能となる。In summary, in such a monitor device, detection of the shunt sound by the microphone enables
The blood flow condition at the shunt formation site can be continuously and automatically monitored.If the blood flow condition at the shunt formation site becomes clogged and the blood flow condition deteriorates, based on the change in the detected value of the shunt sound. The alarm generating means is automatically activated, and the abnormality can be notified to the patient at an early stage. Therefore, the patient does not need to perform auscultation to monitor the blood flow state, and is completely free from troublesome labor and its pain.
With such a monitor device, there is no need to worry about forgetting to check the blood flow state as in conventional auscultation, and unlike auscultation performed at intervals of several hours, there is no delay in the detection of the occurrence of a blood clot. Further, the safety is enhanced, and in many cases, the blood flow state can be restored by administration of a blood coagulation inhibitor, a thrombolytic agent, or the like, and the rate of surgery can be effectively reduced.
【０００９】[0009]
【実施例】以下に、本発明をより具体的に明らかにする
ために、本発明の代表的な実施例を、図面に基づいて、
詳細に説明する。EXAMPLES In order to clarify the present invention more specifically, typical examples of the present invention will be described below with reference to the drawings.
The details will be described.
【００１０】先ず、図１には、内シャントが従来と同様
に形成されている腕部に対して、血液の流通に対応した
シャント音を継続的に検知するマイクロフォン１０が、
絆創膏８を用いて装着された状態が示されており、ま
た、手首には着脱可能なベルト９により警報装置１４が
装着され、それらマイクロフォン１０と警報装置１４
が、導線（図示していない）によって結ばれ、マイクロ
フォン１０にて継続的に検知されるシャント音は、電気
信号に変換されて警報装置１４に伝えられるようになっ
ている。なお、内シャントは、手首からやや心臓よりの
部位で、身体の深部にある動脈２のうちの一本と体表面
側にある静脈４とが結合されて、形成されており、その
結合部６で血流がバイパスされ、静脈４の血流量が増加
せしめられている。従って、血液透析を行なう際には、
このシャント部分、即ち動脈化された静脈部分に対して
穿刺針を刺し、更に血液ポンプで引くことによって、２
００〜８００ml／min 程度の血流量で血液を体外へ取り
出すことができ、以て体外循環を良好に行なうことがで
きるようになっている。First, in FIG. 1, there is shown a microphone 10 for continuously detecting a shunt sound corresponding to the circulation of blood in an arm portion in which an inner shunt is formed as in the conventional case.
A state in which the bandage 8 is used for wearing is shown, and an alarm device 14 is attached to the wrist by a detachable belt 9, and the microphone 10 and the alarm device 14 are attached.
However, a shunt sound continuously connected by a conductor (not shown) and continuously detected by the microphone 10 is converted into an electric signal and transmitted to the alarm device 14. The inner shunt is formed by connecting one of the arteries 2 in the deep part of the body and the vein 4 on the body surface side at a part slightly from the wrist to the heart, and the connecting part 6 thereof. The blood flow is bypassed by and the blood flow in the vein 4 is increased. Therefore, when performing hemodialysis,
By puncturing the shunt portion, that is, the arterialized vein portion with a puncture needle and further pulling with a blood pump, 2
Blood can be taken out of the body at a blood flow rate of about 00 to 800 ml / min, so that the extracorporeal circulation can be performed well.
【００１１】そして、前記マイクロフォン１０は、かか
るシャント形成部位に近接して、シャント音が良好に検
知され得る位置に合わせて装着される。図１では、動脈
２と静脈４の結合部６からやや心臓よりの血管上に位置
して固定されている。なお、そのようなシャント音が良
好に検知され得る位置は、患者によって異なるため、マ
イクロフォン１０を装着する際には、予め聴診によって
最適な位置が確認される。Then, the microphone 10 is mounted in close proximity to the shunt forming portion in accordance with a position where the shunt sound can be favorably detected. In FIG. 1, the joint 2 between the artery 2 and the vein 4 is located and fixed slightly above the blood vessel from the heart. Since the position where such a shunt sound can be favorably detected differs depending on the patient, the optimum position is confirmed by auscultation in advance when the microphone 10 is attached.
【００１２】ところで、警報装置１４は、図２に示され
る如き系統図に従って、電源１２、判断回路１６、制御
回路１８、ブザー２０が接続されて、構成されている。
そして、マイクロフォン１０がシャント形成部位におけ
る血液の流通に対応して継続的に検知したシャント音の
検出値は、判断回路１６に入力されるようになってい
る。また、かかる判断回路１６では、継続して入力され
る検出値が、予め設定された下限値と比較されるように
なっており、その検出値が下限値を下回って、許容範囲
を外れた場合には、その情報を制御回路１８に入力せし
めるようになっている。それ故、血栓にて血管が詰まり
始めて、血流状態が悪化し、それに伴ってシャント音が
低下し、マイクロフォン１０における検出値が変化する
と、所定の段階で制御回路１８にその情報が送られるの
であり、更にその情報を受けて、警報発生手段たるブザ
ー２０に作動信号が送られ、警報音が発生せしめられる
ようになっている。The alarm device 14 is constructed by connecting the power supply 12, the judgment circuit 16, the control circuit 18, and the buzzer 20 according to the system diagram as shown in FIG.
Then, the detection value of the shunt sound continuously detected by the microphone 10 in response to the circulation of blood in the shunt formation site is input to the determination circuit 16. Further, in the determination circuit 16, the continuously input detection value is compared with a preset lower limit value, and when the detection value falls below the lower limit value and is outside the allowable range. The information is input to the control circuit 18. Therefore, when the blood vessel starts to be clogged by the thrombus, the blood flow state deteriorates, the shunt noise decreases accordingly, and the detection value in the microphone 10 changes, the information is sent to the control circuit 18 at a predetermined stage. In addition, upon receiving the information, an operation signal is sent to the buzzer 20 which is an alarm generation means, and an alarm sound is generated.
【００１３】それ故、患者は、毎日何度も聴診を行なわ
なくても、血流状態の悪化を警報音によって早期に知る
ことができるのであり、直ちに病院へ連絡して、早急に
処置を受けることが可能となる。そして、多くの場合に
おいて、注射や点滴等によって、ヘパリン等の血液凝固
阻止剤や、ウロキナーゼ、プラスミノーゲン・アクチベ
ター等の血栓溶解剤の投与を受けることによって、血流
状態を早期に回復させることができ、手術に至る割合が
効果的に低減される。Therefore, the patient can know the deterioration of the blood flow at an early stage by an alarm sound without conducting auscultation many times every day. Immediately contact the hospital for immediate treatment. It becomes possible. In many cases, the blood flow state is recovered early by receiving an anticoagulant such as heparin or a thrombolytic agent such as urokinase or plasminogen / activator by injection or infusion. And the rate of surgery is effectively reduced.
【００１４】以上、本発明の代表的な実施例について詳
細に説明してきたが、本発明が、上記の実施例の記載に
よって、何等の制約をも受けるものでないことは、言う
までもないところである。また、本発明には、本発明の
趣旨を逸脱しない限りにおいて、当業者の知識に基づい
て種々なる変更、修正、改良等を加え得るものであるこ
とが、理解されるべきである。Although the representative embodiments of the present invention have been described in detail above, it goes without saying that the present invention is not restricted by the description of the above embodiments. Further, it should be understood that various changes, modifications, improvements and the like can be added to the present invention based on the knowledge of those skilled in the art without departing from the spirit of the present invention.
【００１５】例えば、上記の実施例では、内シャント形
成部位における血流状態のモニター装置について説明し
たが、本発明が外シャント形成部位に対しても良好に適
用され得ることは言うまでもないところである。また、
マイクロフォン１０は、上記の実施例では、絆創膏８に
て腕部に固定されていたが、ベルトを用いて、固定する
こともでき、更に、通常は、一つのマイクロフォン１０
にて良好にシャント音を検知することができるが、必要
に応じて、複数個のマイクロフォン１０を設けて、シャ
ント音をより確実に検知し得るようにすることも可能で
ある。そして、また、前記実施例では、警報発生手段と
してブザーのみが使用されていたが、ランプの点滅等を
併用するようにしても何等差し支えない。For example, in the above-mentioned embodiment, the blood flow condition monitoring device at the inner shunt formation site has been described, but it goes without saying that the present invention can be well applied to the outer shunt formation site. Also,
Although the microphone 10 is fixed to the arm portion with the adhesive bandage 8 in the above-described embodiment, it can be fixed using a belt, and normally, one microphone 10 is used.
Although it is possible to detect the shunt sound satisfactorily, it is possible to provide a plurality of microphones 10 as necessary so that the shunt sound can be detected more reliably. Further, in the above-described embodiment, only the buzzer is used as the alarm generating means, but it does not matter even if the blinking of the lamp is used together.
【図１】内シャントが形成されている腕部に対して、本
発明に従う血流状態のモニター装置が装着されている状
態を示す説明図である。FIG. 1 is an explanatory view showing a state in which a blood flow state monitoring device according to the present invention is attached to an arm portion in which an inner shunt is formed.
【図２】図１のモニター装置の系統図である。FIG. 2 is a system diagram of the monitor device of FIG.
２ 動脈 ４ 静脈 ６ 結合部 ８ 絆創膏 ９ ベルト １０ マイクロフォン １２ 電源 １４ 警報装置 １６ 判断回路 １８ 制御回路 ２０ ブザー 2 arteries 4 veins 6 connection parts 8 adhesive bandages 9 belts 10 microphones 12 power supply 14 alarm device 16 judgment circuit 18 control circuit 20 buzzer
Claims (1)
かかるシャント形成部位における血液の流通に対応した
シャント音を継続して検知するための少なくとも一つの
マイクロフォンと、血流状態の悪化によるシャント音の
低下に従って変化する該マイクロフォンにおける検出値
を、予め設定された下限値と比較するための判断回路
と、検出値が設定値を下回った場合に信号を発する制御
回路と、該制御回路の発した信号に基づいて作動せしめ
られる警報発生手段とを含んで構成されるシャント形成
部位における血流状態のモニター装置。1. A device is disposed in proximity to a shunt formation site,
At least one microphone for continuously detecting a shunt sound corresponding to the circulation of blood in the shunt formation site, and a detection value of the microphone that changes according to a decrease in the shunt sound due to the deterioration of the blood flow state are preset. And a lower limit value, a control circuit for issuing a signal when the detected value is lower than a set value, and an alarm generating means which is activated based on the signal issued by the control circuit. Device for monitoring blood flow at the shunt formation site.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP03309896A JP3083378B2 (en) | 1991-10-28 | 1991-10-28 | Monitoring device for blood flow status at shunt formation site |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP03309896A JP3083378B2 (en) | 1991-10-28 | 1991-10-28 | Monitoring device for blood flow status at shunt formation site |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH05115547A true JPH05115547A (en) | 1993-05-14 |
| JP3083378B2 JP3083378B2 (en) | 2000-09-04 |
Family
ID=17998630
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP03309896A Expired - Lifetime JP3083378B2 (en) | 1991-10-28 | 1991-10-28 | Monitoring device for blood flow status at shunt formation site |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP3083378B2 (en) |
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