JPH04285909A - Cleaning composition for contact lens - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

[Detailed description of the invention]

0001

FIELD OF THE INVENTION This invention relates to contact lens cleaning compositions containing solid particles.

0002

2. Description of the Related Art Since contact lenses are worn directly on the eyes, proteins, lipids, etc., which are secretions from the eyes, may adhere to the lens surface, causing stains and clouding. Furthermore, if the lens is worn for a long period of time without removing this dirt, not only the wettability of the lens surface and the optical characteristics of the lens will be impaired, but also the eyeballs may be damaged. Therefore, contact lenses must be thoroughly cleaned before use.

[0003] Conventional hard contact lenses made of polymethyl methacrylate are chemically stable and can be used with a wide variety of cleaning agents.
Because they are easy to rinse, there are relatively few problems with dirt adhesion, but after years of use, dirt that is difficult to remove can accumulate. In addition, in recent years, contact lenses made of polymethyl methacrylate have been found to cause complications due to insufficient oxygen supply to the cornea of the eye, and lenses with high oxygen permeability containing organic silane compounds and fluorine compounds have been developed. Improvements are being made. However, in general, when worn for a long time, these lenses tend to get dirty and break more easily than conventional hard contact lenses made of polymethyl methacrylate, so they have the disadvantage that cleaning the lenses is difficult.

Conventionally, surfactant solutions or proteolytic enzymes have been used as cleaning agents for contact lenses, but depending on the lens material, these cleaning agents alone may not have a sufficient cleaning effect. Furthermore, proteolytic enzymes have the disadvantage that they have a low removal effect on stains other than proteins and require time to perform the work. Therefore, inorganic abrasives such as those disclosed in JP-A-63-146017 and JP-A-63-159821
A surfactant solution containing an organic abrasive as disclosed in JP-A-1-172815 or a mixed inorganic and organic abrasive as disclosed in JP-A-1-172815 is used to remove stains. Contact lens cleaning compositions have been proposed for physically removing .

[0005]

The abrasives contained in conventional contact lens cleaning agents are either inorganic or organic, or a mixture thereof. Although inorganic abrasives are hard and have abrasive power and are good at removing dirt, they have the risk of damaging and deforming lenses. On the other hand, organic abrasives are soft and have good shape retention without scratching the lens, but have weak cleaning power. Also, JP-A-1-17281
The simple mixture of inorganic and organic abrasives disclosed in Publication No. 5 does not compensate for the drawbacks of both and utilize their advantages.

Therefore, the present invention aims to solve the deficiencies by taking advantage of the drawbacks of both organic and inorganic abrasives. The objective is to provide a cleaning agent that does not cause lens deformation and has a high cleaning effect by mixing the cleaning agent with a polishing agent at a predetermined weight ratio.

[0007]

[Means for solving the problem] As a result of intensive research to achieve the above object, we have found that by limiting the composition and particle size of the solid particles contained within a predetermined range, dirt can be removed easily and lens deformation does not occur. It has been discovered that contact lens cleaning compositions can be formed.

That is, the contact lens cleaning composition of the present invention contains organic solid particles and inorganic solid particles in a cleaning liquid containing a surfactant in a weight ratio of organic solid particles:inorganic solid particles=80. 99:20 to 1.

Furthermore, the particle size of the solid particles used in the present invention is preferably 0.5 to 12 μm for organic solid particles, and 0.05 to 2.0 μm for inorganic solid particles.

The present invention will be explained in detail below.

Examples of the solid particles used in the present invention include inorganic particles such as silica, alumina, and calcium carbonate, and organic particles such as nylon powder, benzoguanamine resin, melamine resin, and polyethylene. Various organic polymers can be mentioned, such as resins.

In the present invention, the solid particles in the cleaning liquid have a weight ratio of organic solid particles:inorganic solid particles=80 to 99.
:20-1 is essential. This weight ratio is more preferably 85 to 95 parts of organic solid particles and 15 to 5 parts of inorganic solid particles. If the weight ratio of the organic solid particles is less than 80 parts (the weight ratio of the inorganic solid particles exceeds 20 parts), the risk of damaging the lens increases;
When the weight ratio of organic solid particles exceeds 99 parts (when the weight ratio of inorganic solid particles is less than 1 part), stain removal is insufficient.

Next, the particle size of the organic solid particles is 0.5 to 12
Although it is essential that it is 0.1 μm, more preferably 0.
The thickness is preferably 5 to 5 μm. If the particle size is smaller than 0.5 μm or exceeds 12 μm, stain removal becomes difficult and is not preferred.

[0014] The particle size of the inorganic solid particles is 0.05 to 2.0.
Although it is essential that it is 0.1 μm, more preferably 0.
The thickness is preferably 1 to 1.0 μm. When the particle size is smaller than 0.05 μm, stain removal is difficult, and the particle size is 2.0 μm.
If it exceeds 0 μm, it is not preferable because it will cause scratches on the contact lens.

[0015] In addition to these ingredients, specific surfactants and proteolytic enzymes may be added as detergents to remove lipid components, and preservatives may also be added to stabilize quality. Useful.

[0016]

[Function] There are many contact lens cleaning compositions that contain solid particles, but due to the difference in the physical cleaning effect of the solid particles, there have been problems with cleaning power, scratches, and lens shape retention. In the present invention, these problems can be alleviated by mixing inorganic solid particles and organic solid particles having a predetermined particle size at a predetermined weight ratio. Furthermore, the cleaning effect was improved by limiting the mixing ratio of organic solid particles and inorganic solid particles. Furthermore, by limiting the particle size of the solid particles, it was possible to improve the lens' shape retention and scratch resistance.

[0017]

[Examples] Examples of the present invention are shown below, but the present invention is not limited to these examples.

Characteristics of the cleaning composition in use The cleaning composition shown in Table 1 was used to evaluate the characteristics of the product of the present invention in use. This cleaning composition was prepared by adding purified water to an anionic surfactant, dissolving it in a hot bath at about 50 degrees, and then adding a predetermined amount of solid particles. The target lenses are high oxygen permeability hard contact lenses made of siloxanyl methacrylate, alkyl methacrylate, and fluoromethacrylate (
The following items 1 and 2 were evaluated using A) and a low oxygen permeable hard contact lens (B) made of siloxanyl methacrylate and alkyl methacrylate. The results are shown in Table 2.

1. Easy to scratch Hand cleaning (procedure): Apply 3 drops of cleaning composition to the lens and apply 1 drop with your fingers.
After washing for 0 minutes, rinse with running water. cleaning composition every 3 minutes
Add drop by drop. Repeat this cycle three times and use a slit lamp to check the extent of scratches on the lens surface before and after cleaning.

(Evaluation): - No scratches + Scratches 2. Cleanability (procedure): Clean the lenses with artificial dirt (proteins and lipid components in tear fluid) by hand.

○… Dirt is completely removed after 3 minutes of washing ×… 3
Dirt cannot be completely removed by washing for a few minutes.

[0022]

[Table 1]

[0023]

[Table 2]

[0024]

As described above, according to the present invention, organic solid particles having a particle size of 0.5 to 12 μm and inorganic solid particles having a particle size of 0.05 to 2.0 μm, which act as an abrasive, are mixed in a predetermined ratio. By mixing them, it is possible to take advantage of the advantages of inorganic solid particles and organic solid particles while compensating for their respective disadvantages. This has the effect of providing a contact lens cleaning composition with excellent cleaning effects.

Claims (2)

[Claims] Claim 1: A cleaning solution containing a surfactant contains organic solid particles and inorganic solid particles in a weight ratio of organic solid particles:inorganic solid particles = 80 to 99:20 to 1. A contact lens cleaning composition characterized by: 2. The particle size of the solid particles is 0.5 to 12 μm for organic solid particles and 0.05 μm for inorganic solid particles.
The contact lens cleaning composition according to claim 1, wherein the contact lens cleaning composition has a particle diameter of 2.0 μm.