JPH04126556U - Infusion filter - Google Patents

Abstract

(57) [Summary] [Structure] Inside a cylindrical hollow body (1), a fixing member (in which a large number of permanent hydrophilic porous hollow fiber membranes (2) are bundled in a U-shape and both open ends are fixed) is installed. 3), the space inside the hollow body (1) is separated into the inlet side and the outlet side by the fixing member (3) and the membrane wall of the hollow fiber membrane (2), and the space outside the hollow fiber membrane (2) is An infusion filter that is provided so as to face the inlet side, and is characterized by having a pressurizing device (4) such as a rubber bulb for applying pressure to the liquid present in the space on the inlet side. filter. [Effect] Pressurizing device for infusion filter of the present invention (4)
By applying pressure to the stock solution and expelling unnecessary air within the hollow fibers, a sufficiently stable and high flow rate can be ensured even in the early stages of use of the filter.

Description

[Detailed explanation of the idea]

0001

[Industrial application field]

This invention uses a permanently hydrophilic porous hollow fiber membrane that is useful in various fields such as the medical field. Regarding infusion filters.

0002

[Conventional technology]

Conventional infusion filters generally use flat membranes. Also, this flat membrane It is also known that the filter itself is made more compact by using a porous hollow fiber membrane instead. It is. Porous hollow fiber membranes used in infusion filters are generally hydrophilic. always needed. In addition, when using this infusion filter for medical purposes, the membrane should be It is desirable that it be in a dry state. From this point of view, conventionally, porous hollow fiber membranes were used. The method used was to apply a water-soluble surfactant to the surface to make it hydrophilic. deer This method has some inconveniences, such as the need to clean the membrane surface before use. . Therefore, in order to eliminate this inconvenience, we developed a permanent hydrophilic porous hollow structure that does not use surfactants. There are products that use thread membranes for infusion filters.

0003

[Problem that the idea aims to solve]

Infusion filters must maintain a stable and desired flow rate in their fluid transport. is usually required. However, conventional transport using permanently hydrophilic porous hollow fiber membranes Liquid filters were still insufficient in this respect. For example, in a permanently hydrophilic porous medium The entire membrane of the empty fiber membrane is highly and uniformly hydrophilized, so it During this period, the entire membrane becomes wet rapidly, and air accumulates on the membrane surface, causing water to flow through the membrane. permeation may be obstructed and the flow rate may be insufficient. For example, generally hollow Thread membranes tend to trap air in the core of the thread, which may cause the flow rate to become unstable. be. On the other hand, unnecessary air inside the module of an infusion filter using a flat membrane is removed. One way to do this is to install an air permeable membrane at the top of the module (Utility Model Publication No. 60-21091). Publications, etc.) are known. However, this technology is related to filters using flat membranes. Therefore, even if it is applied to a filter using a hollow fiber membrane, it cannot be expected to be effective.

0004 This invention was devised to solve the above-mentioned problems, and its purpose is to This is an infusion filter using a hydrophilic porous hollow fiber membrane. Another object of the present invention is to provide an infusion filter that can ensure a stable and high flow rate.

[0005]

[Means to solve the problem]

The present invention has a hollow body having an inlet and an outlet, and has a permanent hydrophilic polyurethane inside the hollow body. It has a fixing member to which the open end of the porous hollow fiber membrane is fixed, and the fixing member and the hollow fiber membrane are connected together. A wall separates the interior of the hollow body into a space desired for the inlet and a space desired for the outlet. and an infusion filter provided such that the outside of the hollow fiber membrane faces the space desired for the inlet. router, which has a pressurizing device at the inlet for applying pressure to the liquid in the desired space. This is an infusion filter that is characterized by:

[0006]

[Effect]

Since the infusion filter of the present invention has the above-mentioned pressurizing device, it is necessary to Fill the inlet side with liquid, and use this pressurizing device to pump the liquid in the desired space at the inlet (i.e. By applying pressure to the undiluted solution, air in the hollow fiber membrane and the core of the fiber can be easily expelled. can. If the infusion is started after this, the flow rate will be sufficiently stable and high even in the early stages of use. quantity can be secured. In addition, the infusion filter of the present invention has a hollow fiber exterior. Since the filtration method uses a filtration method in which the liquid passes from the inside to the inside, it has a lower The filtration area is large. Furthermore, since the inside of the hollow fiber is less likely to be contaminated than the outside, A better filtrate with less contamination can be obtained compared to internal-to-external filtration methods. .

[0007]

【Example】

Hereinafter, embodiments of the present invention will be described in detail with reference to the drawings.

[0008] FIG. 1 is a schematic cross-section showing one embodiment of the infusion filter of the present invention. this The infusion filter shown in FIG. It has an inlet pipe 5 and an outlet pipe 6 on the lower side for extracting the filtrate. And this Inside the hollow body 1, a large number of permanent hydrophilic porous hollow fiber membranes 2 are bundled in a U-shape. A fixing member 3 is fixed to both open ends. This fixing member 3 and hollow fiber membrane 2 The space inside the hollow body 1 is separated into an inlet side and an outlet side by the membrane wall. Change In addition, a backflow prevention device 7 and a rubber bulb (pressure device 4) are installed in the middle of the inlet pipe 5 for the stock solution. Next, pressure is applied to the raw solution side by compressing the rubber bulb 4. The structure is as follows.

[0009] As the hollow fiber membrane 2, various conventionally known permanent hydrophilic porous hollow fiber membranes are used. I can be there. For example, a polyolefin porous membrane can be made permanent using a water-insoluble hydrophilic agent. Hollow fiber membranes obtained by making them hydrophilic have excellent durability and are capable of high-flow infusion. and is suitable for medical use. Examples of this water-insoluble hydrophilic agent include ethylene -Vinyl alcohol copolymer, ethylene-vinyl alcohol-vinyl acetate copolymer There are polymers, and conventionally known ones can be used without restriction.

[0010] As the pressurizing device 4, a flexible rubber pressurizing device as shown in Fig. 1 is preferable because it is simple, but it is not possible to apply pressure to the stock solution side to effectively remove unnecessary air. If so, there are no particular limitations. From the point of view of effective air removal, it is particularly preferable to use an apparatus that can generate a pressure of 0.2 kg/cm ² or more on the undiluted solution side.

[0011] The backflow prevention device 7 prevents the stock solution from flowing back when pressurized by the pressure device 2. In order to do this, valves etc. are provided as necessary. By also providing this backflow device, This enables even more efficient pressurization.

0012 Note that the pressurizing device 4 and the backflow prevention device 7 are not limited to the example shown in FIG. Any device that can be built into the structure and that can perform the specified function. I can't help it. In addition, hollow fiber membranes are used for the hollow body 1 and the fixing member 3. Various conventionally known components for infusion filters can be used without restriction. It is possible.

[0013] To use the infusion filter shown in Figure 1, first inject the stock solution through tube 5. The space on the inlet side of the hollow body 1 is filled with the stock solution. Next, compress the rubber bulb 4 to make the undiluted solution. Apply appropriate pressure. This makes it easy to remove air that has accumulated on the two sides of the hollow fiber membrane. If you start infusion after this, a stable high flow rate can be obtained from the beginning of use. It will be done.

[0014]

[Effect of the idea]

As explained above, the infusion filter of the present invention uses a pressurizing device to This allows you to easily expel unnecessary air from the It is possible to secure a stable and high flow rate. In addition, flow stability, filtration performance, Infusion filters are especially suitable for medical applications due to their excellent durability and durability. It is.

[Brief explanation of drawings]

FIG. 1 is a schematic cross section showing an embodiment of the present invention.

[Explanation of symbols]

1 Hollow body 2 Permanent hydrophilic porous hollow fiber membrane 3 Fixed member 4 Rubber ball (pressure device) 5 Inlet pipe 6 Outlet pipe 7 Backflow prevention device

Claims (1)

[Scope of utility model registration request] Claim 1: A fixing member (3) having a hollow body (1) having an inlet and an outlet, and having an open end of a permanent hydrophilic porous hollow fiber membrane (2) fixed inside the hollow body (1). The fixing member (3) and the membrane wall of the hollow fiber membrane (2) separate the interior of the hollow body (1) into a space desired for the inlet and a space desired for the outlet, and This infusion filter is provided so that the outside of the thread membrane (2) faces the space desired at the inlet, and is equipped with a pressurizing device (4) for applying pressure to the liquid present in the space desired at the inlet. An infusion filter comprising: