JPH038334Y2 - - Google Patents
Info
- Publication number
- JPH038334Y2 JPH038334Y2 JP1984011550U JP1155084U JPH038334Y2 JP H038334 Y2 JPH038334 Y2 JP H038334Y2 JP 1984011550 U JP1984011550 U JP 1984011550U JP 1155084 U JP1155084 U JP 1155084U JP H038334 Y2 JPH038334 Y2 JP H038334Y2
- Authority
- JP
- Japan
- Prior art keywords
- microporous film
- plastic sheet
- over
- filter
- laminate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002985 plastic film Substances 0.000 claims description 22
- 239000011148 porous material Substances 0.000 claims description 12
- 230000002209 hydrophobic effect Effects 0.000 claims description 8
- 238000003475 lamination Methods 0.000 claims description 4
- 238000000034 method Methods 0.000 description 6
- 238000012864 cross contamination Methods 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 238000012856 packing Methods 0.000 description 4
- 239000002904 solvent Substances 0.000 description 4
- 230000000694 effects Effects 0.000 description 3
- 239000004033 plastic Substances 0.000 description 3
- 229920003023 plastic Polymers 0.000 description 3
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 description 2
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 2
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 230000000740 bleeding effect Effects 0.000 description 2
- 239000004745 nonwoven fabric Substances 0.000 description 2
- 229920006255 plastic film Polymers 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 229920006284 nylon film Polymers 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000002787 reinforcement Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Landscapes
- Separation Using Semi-Permeable Membranes (AREA)
- Filtering Materials (AREA)
- Laminated Bodies (AREA)
Description
【考案の詳細な説明】
(産業上の利用分野)
本考案はマルチフイルター用微多孔性フイルム
積層体に関するものである。[Detailed Description of the Invention] (Industrial Application Field) The present invention relates to a microporous film laminate for a multi-filter.
(従来技術とその問題点)
微多孔性フイルムは精密過用材として広く
多方面で用いられている。特に最近、生化学方面
で蛋白、核酸等の各種微量試験において、一度に
数多くの試料を微量過する場合が極めて多くな
り、このため過材における過面積も当然極く
小さいものが用いられている。例えば直径3〜25
mm程度の過面積のもので、しかも数十ないしそ
れ以上の試料を一度に過する場合が多い。この
ような場合に、通常過開孔の多い過器、いわ
ゆるマルチフイルターが多く使用され、その際
過材としての微多孔性フイルムも、各過開孔毎
に寸法に合わせて1つ宛装着するのが面倒なの
で、各過開孔全多体を共通に覆うようなものが
屡々使用されている。このようにすると、過開
孔への過材の装着は、一枚の微多孔性フイルム
を装着すればすむので、著しく簡略化されたが、
他方、この微多孔性フイルム面を通しての過試
料の面方向の洩れ、にじみ(クロスコンタミネー
シヨン)が生じやすく、各過開孔を通つて過
される試料同志が混り合うという危険性がある。
このような現象を防止することは、とくに微量試
験の場合は極めて重要である。(Prior art and its problems) Microporous films are widely used in many fields as precision overuse materials. Particularly recently, in the field of biochemistry, it has become extremely common to pass a large number of samples in minute quantities at once in various micro-quantity tests for proteins, nucleic acids, etc., and for this reason, the overpass area of the overfill material is naturally extremely small. . For example, diameter 3-25
It has an overarea of about mm, and moreover, dozens or more samples are often passed through at once. In such cases, a filter with many over-open pores, so-called multi-filter, is often used, and at that time, a microporous film as a filter material is also attached to each over-open hole according to its size. Since it is troublesome to do so, a method that commonly covers all the over-open holes is often used. In this way, the installation of the overfill material into the overopen hole was only required by installing a single piece of microporous film, which greatly simplified the process.
On the other hand, leakage and smearing (cross-contamination) of excessive samples in the plane direction through the surface of this microporous film is likely to occur, and there is a risk that samples passing through each excessively open pore will mix with each other. .
Preventing such phenomena is extremely important, especially in the case of trace test.
前記した洩れやにじみの現象を防止するため
に、従来は個々の過開孔の片面又は両面にO−
リングあるいは平パツキンを装着して、より完全
なシールを行なうなど種々の対策が講じられてい
るが、微多孔性フイルム自体が多孔性でかつ親水
性を具備しているで、通常の締付圧力では、わき
洩れ、にじみ(クロスコンタミネーシヨン)は完
全には防止することができないという難点があ
る。 In order to prevent the above-mentioned leakage and bleeding phenomena, O-
Various measures have been taken, such as attaching a ring or flat seal to achieve a more complete seal, but the microporous film itself is porous and hydrophilic, so it cannot be used under normal tightening pressure. However, there is a problem in that leakage and bleeding (cross contamination) cannot be completely prevented.
(考案の目的)
本考案はこのようなクロスコンタミネーシヨン
を完全に防止しうるマルチフイルター用の微多孔
性フイルム積層体を提供することを目的とする。(Object of the invention) The object of the invention is to provide a microporous film laminate for a multi-filter that can completely prevent such cross-contamination.
(考案の構成・作用)
本考案の前記の目的は、微多孔性フイルム3の
片面又は両面に多数の過開孔2を有するプラス
チツクシート1を積層貼合し、この積層貼合によ
りプラスチツクシート1との貼合部分に位置する
微多孔性フイルム3の部分を疎水性となし、プラ
スチツクシート1の過開孔2に位置する微多孔
性フイルム3の部分は親水性を維持させたことを
特徴とするマルチフイルター用微多孔性フイルム
積層体によつて達成される。(Structure and operation of the invention) The above-mentioned object of the invention is to laminate a plastic sheet 1 having a large number of over-open pores 2 on one or both sides of a microporous film 3, and to form a plastic sheet 1 by this laminate and lamination. The part of the microporous film 3 located in the bonded part with the plastic sheet 1 is made hydrophobic, and the part of the microporous film 3 located in the overly open pores 2 of the plastic sheet 1 maintains hydrophilicity. This is achieved by a microporous film laminate for multi-filter.
本考案を図面に示す実施例にもとづいて説明す
る。第1図に本考案の過用微多孔性フイルム積
層体の斜視図、第2図に第1図のA−A線に沿う
断面図を示す。 The present invention will be explained based on embodiments shown in the drawings. FIG. 1 is a perspective view of the overused microporous film laminate of the present invention, and FIG. 2 is a sectional view taken along the line A--A in FIG. 1.
図において1は多数の過開孔2を有するプラ
スチツクシート、3はプラスチツクシート2の片
面に積層貼合された微多孔性フイルムである。 In the figure, 1 is a plastic sheet having a large number of over-open pores 2, and 3 is a microporous film laminated on one side of the plastic sheet 2.
プラスチツクシート1としては、アクリル、ポ
リスチレン、アクリルスチロール、その他のプラ
スチツクシートが用いられる。このプラスチツク
シート1自体が柔軟性でパツキン効果がある場合
にはパツキンとして兼用できるので好ましい。 As the plastic sheet 1, acrylic, polystyrene, acrylic styrene, or other plastic sheets are used. It is preferable that the plastic sheet 1 itself is flexible and has a packing effect, since it can also be used as a packing.
微多孔性フイルムとしては、例えばセルロース
系、ナイロン系等が用いられるが、勿論それ以外
でも使用可能である。 As the microporous film, for example, a cellulose film, a nylon film, etc. are used, but of course other films can also be used.
微多孔性フイルム3とプラスチツクシート1と
の積層貼合方法としては、熱接着(高周波、超音
波接着等を含む)又は接着剤による方法、あるい
はプラスチツクに対しては溶剤であるが、微多孔
性フイルムに対しては非溶剤である薬剤中に微多
孔性フイルムを浸漬し、そのままプラスチツクシ
ートに貼合する方法などがあげられる。之等何れ
の方法によるも、貼合せ部分が密着し、この部分
の微多孔性フイルム部分が疎水性になることが必
要であり、この微多孔性フイルム部分の微孔が消
失してもあるいは存在していても差支えない。 The microporous film 3 and the plastic sheet 1 can be laminated and laminated using thermal adhesion (including high frequency, ultrasonic adhesion, etc.) or adhesives, or for plastics, a solvent may be used. For films, there is a method in which a microporous film is immersed in a non-solvent chemical and then laminated directly onto a plastic sheet. In any of these methods, it is necessary that the bonded parts are in close contact and the microporous film part in this part becomes hydrophobic, and even if the micropores in this microporous film part disappear or do not exist. It doesn't matter if you do.
熱接着によるときは、元々疎水性のプラスチツ
クフイルムが親水性の微多孔性フイルムに一体的
に融合接着されるので、接着部分の微多孔性フイ
ルムは疎水性になる。接着剤を用いるときは、
過開孔部にある微多孔性フイルム部分の多孔性、
親水性が損なわれない様に留意し、一方、貼合部
に位置する微多孔性フイルムの部分は、貼合部の
みならずフイルムの表面まで疎水性になつている
ことが必要である。プラスチツクの溶剤(但し微
多孔性フイルムに対しては非溶剤)中に微多孔性
フイルムを浸漬して、プラスチツクフイルムに貼
合せるときは、プラスチツクが溶けて微多孔性フ
イルムへ浸透するで、貼合せ位置の微多孔性フイ
ルム部分は疎水性になる。第2図においては3′
は疎水性化された微多孔性フイルムの部分であ
る。 When thermal adhesion is used, the originally hydrophobic plastic film is integrally fused and bonded to the hydrophilic microporous film, so the microporous film at the bonded portion becomes hydrophobic. When using adhesive,
The porosity of the microporous film part in the over-open pore area,
Care must be taken not to impair hydrophilicity, and on the other hand, it is necessary that the part of the microporous film located at the bonding area is hydrophobic not only at the bonding area but also at the surface of the film. When a microporous film is dipped in a plastic solvent (but not a solvent for microporous films) and laminated to the plastic film, the plastic melts and penetrates into the microporous film, making the lamination process difficult. The microporous film portion at the position becomes hydrophobic. In Figure 2, 3'
is a portion of the microporous film that has been made hydrophobic.
プラスチツクシートの厚さは0.1〜3.0mmが適当
であるが、勿論之に限定されない。又過開孔寸
法及び形状は任意であるが、通常径3mm以上とす
る。必要に応じて例えば5mm×40mmの角型として
もよい。 The thickness of the plastic sheet is suitably 0.1 to 3.0 mm, but is not limited thereto. The size and shape of the over-open hole are arbitrary, but the diameter is usually 3 mm or more. If necessary, it may be made into a square shape of, for example, 5 mm x 40 mm.
本考案の微多孔性フイルム積層体をマルチフイ
ルターに装着して多数の過開孔により並列過
を実施する態様を第3図及び第4図により説明す
る。 A mode in which the microporous film laminate of the present invention is mounted on a multi-filter and parallel filtering is performed using a large number of over-open holes will be explained with reference to FIGS. 3 and 4.
第4図は多数の過開孔12有するプラスチツ
クシート11と微多孔性フイルム13とからなる
本考案の微多孔性フイルム積層体を、室22を有
する本体16と流通孔21を有する中間部18と
過開孔20有する上部17とからなるマルチフ
イルターに装着した状態を示す断面図、第5図は
同じく一部切欠斜視図である。なお図において1
4はパツキン、15は必要に応じて微多孔性フイ
ルム13の下面に補強及び水保留のために介在又
は接着される不織布である。この場合、自然状態
では過開孔に水溶液を保持した状態にしてお
き、必要時に加圧又は減圧すれば過することが
できる。又23は図示せざる真空ポンプに連通す
る導孔である。 FIG. 4 shows a microporous film laminate of the present invention consisting of a plastic sheet 11 having a large number of over-open pores 12 and a microporous film 13, and a main body 16 having chambers 22 and an intermediate portion 18 having flow holes 21. FIG. 5 is a sectional view showing a state where the multi-filter is attached to a multi-filter consisting of an upper part 17 having over-open holes 20, and a partially cutaway perspective view. In the figure, 1
4 is a packing, and 15 is a nonwoven fabric interposed or bonded to the lower surface of the microporous film 13 for reinforcement and water retention, if necessary. In this case, the aqueous solution is kept in the over-open pores in the natural state, and can be removed by pressurizing or reducing the pressure when necessary. Further, 23 is a guide hole communicating with a vacuum pump (not shown).
上記の如く、本考案の微多孔性フイルム積層体
をマルチフイルターに装着することにより、一度
に多数の試料を、各試料相互間でのクロスコンタ
ミネーシヨンを生ずることなしに過することが
可能になるという実用的効果が奏される。 As mentioned above, by attaching the microporous film laminate of the present invention to a multi-filter, it is possible to pass a large number of samples at once without causing cross-contamination between each sample. This has the practical effect of
なお、本考案の微多孔性フイルム積層体のプラ
スチツクシート開孔部を、通常のコロニー面積よ
りも小さくすることにより、従来のメンブラン法
による液体又は気体中の生菌数の測定がより簡易
になるという効果が奏せられる。 Furthermore, by making the plastic sheet openings of the microporous film laminate of the present invention smaller than the normal colony area, it becomes easier to measure the number of viable bacteria in liquid or gas using the conventional membrane method. This effect is achieved.
第1図は本考案の過用微多孔性フイルム積層
体の斜視図、第2図は第1図A−A線に沿う断面
図、第3図は本考案の過用微多孔性積層体をマ
ルチフイルターに装着した態様を示す断面図、第
4図は同上一部切欠斜視図である。
1:プラスチツクシート、2:過開孔、3:
微多孔性フイルム、11:プラスチツクシート、
12:過開孔、13:微多孔性フイルム、1
4:パツキン、15:不織布、16:マルチフイ
ルター本体、17:上部、18:中間部、20:
過開孔、21:流通孔、22:室、23:導
孔。
Figure 1 is a perspective view of the overused microporous film laminate of the present invention, Figure 2 is a sectional view taken along the line A-A in Figure 1, and Figure 3 is the overused microporous film laminate of the present invention. FIG. 4 is a cross-sectional view showing a state in which the multi-filter is mounted, and FIG. 4 is a partially cutaway perspective view of the same as above. 1: Plastic sheet, 2: Over-perforated, 3:
Microporous film, 11: plastic sheet,
12: Excessive pores, 13: Microporous film, 1
4: Packing, 15: Non-woven fabric, 16: Multi-filter body, 17: Upper part, 18: Middle part, 20:
Over-open pore, 21: Communication hole, 22: Chamber, 23: Guide hole.
Claims (1)
過開孔2を有するプラスチツクシート1を積層貼
合し、この積層貼合によりプラスチツクシート1
との貼合部分に位置する微多孔性フイルム3の部
分を疎水性となし、プラスチツクシート1の過
開孔2に位置する微多孔性フイルム3の部分は親
水性を維持させたことを特徴とするマルチフイル
ター用微多孔性フイルム積層体。 A plastic sheet 1 having a large number of over-open pores 2 is laminated on one or both sides of a microporous film 3, and the plastic sheet 1 is formed by this lamination and lamination.
The part of the microporous film 3 located in the bonded part with the plastic sheet 1 is made hydrophobic, and the part of the microporous film 3 located in the overly open pores 2 of the plastic sheet 1 maintains hydrophilicity. A microporous film laminate for multi-filters.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1155084U JPS60124619U (en) | 1984-01-30 | 1984-01-30 | Microporous film laminate for multi-filter |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1155084U JPS60124619U (en) | 1984-01-30 | 1984-01-30 | Microporous film laminate for multi-filter |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS60124619U JPS60124619U (en) | 1985-08-22 |
JPH038334Y2 true JPH038334Y2 (en) | 1991-02-28 |
Family
ID=30493772
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP1155084U Granted JPS60124619U (en) | 1984-01-30 | 1984-01-30 | Microporous film laminate for multi-filter |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS60124619U (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2004512155A (en) * | 1999-05-05 | 2004-04-22 | ミリポア・コーポレイション | Filtration equipment including wells |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5150467U (en) * | 1974-10-16 | 1976-04-16 |
-
1984
- 1984-01-30 JP JP1155084U patent/JPS60124619U/en active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2004512155A (en) * | 1999-05-05 | 2004-04-22 | ミリポア・コーポレイション | Filtration equipment including wells |
Also Published As
Publication number | Publication date |
---|---|
JPS60124619U (en) | 1985-08-22 |
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