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JPH03284264A - Injection needle made of ceramics - Google Patents

Injection needle made of ceramics

Info

Publication number
JPH03284264A
JPH03284264A JP2086788A JP8678890A JPH03284264A JP H03284264 A JPH03284264 A JP H03284264A JP 2086788 A JP2086788 A JP 2086788A JP 8678890 A JP8678890 A JP 8678890A JP H03284264 A JPH03284264 A JP H03284264A
Authority
JP
Japan
Prior art keywords
injection needle
ceramics
magnetic
ceramic
needle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2086788A
Other languages
Japanese (ja)
Inventor
Sadayuki Sakuma
佐久間 貞行
Yoshinari Kozuka
小塚 義成
Shuhei Toyoda
周平 豊田
Takashi Ota
隆 太田
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NGK Insulators Ltd
Original Assignee
NGK Insulators Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NGK Insulators Ltd filed Critical NGK Insulators Ltd
Priority to JP2086788A priority Critical patent/JPH03284264A/en
Publication of JPH03284264A publication Critical patent/JPH03284264A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B2017/00831Material properties
    • A61B2017/00902Material properties transparent or translucent
    • A61B2017/00911Material properties transparent or translucent for fields applied by a magnetic resonance imaging system

Landscapes

  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Materials For Medical Uses (AREA)

Abstract

PURPOSE:To suitably use the title injection needle in the medical action carried out in a magnetic field by constituting the injection needle of non-magnetic ceramics. CONSTITUTION:An injection needle 4 is constituted of non-magnetic ceramics. As the non-magnetic ceramics constituting this ceramics injection needle, one having strength of 100MPa and fracture toughness of 0.5MN/m<3/2> or more is suitably used from the aspect of physical properties. Further, the ceramics injection needle 4 desirably has such a shape that the angle alpha of inclination of the tip of a needle part is 14+ or -4 deg., an inner diameter dimension is 0.1mmphi or more and an outer diameter dimension is 2mmphi or less and the surface of the needle part is desirably set to surface roughness of 1mum or less. Ceramics is molded into a pipe shape by extrusion or injection molding to be fired and the obtained ceramics hollow body is cut into proper length and one end part of the cut one is cut and ground using a diamond cutter to be formed as a single taper part 2 having an inclined surface.

Description

【発明の詳細な説明】 (技術分野) 本発明は、注射針に係り、特に磁気を用いる医療技術系
等において好適に用いられるセラミックス製注射針に関
するものである。
DETAILED DESCRIPTION OF THE INVENTION (Technical Field) The present invention relates to an injection needle, and particularly to a ceramic injection needle that is suitably used in medical technology using magnetism.

(背景技術) 近年における医療分野の技術進歩は目覚ましいものがあ
り、その一つとして、MRI  (MagneticR
esonance Tmaging :磁気共鳴描画)
などの、磁気を用いて磁界中で治療や検査等を行なう技
術が開発されている。
(Background technology) Technological advances in the medical field in recent years have been remarkable, one of which is MRI (Magnetic®
esonance Tmaging: magnetic resonance imaging)
Technologies such as , which use magnetism to perform treatments, tests, etc. in a magnetic field have been developed.

ところが、かかるMHI装置等において、強力な磁界中
で医療行為を行なうに際しては、従来から用いられてい
る金属製の注射針を用いると、該注射針に磁気力が作用
し、また磁界を乱すこととなるために、その使用、延い
ては医療行為が著しく制約されてしまうといった、大き
な問題を内在していたのである。
However, when performing medical treatment in a strong magnetic field in such an MHI device, if a conventionally used metal injection needle is used, a magnetic force acts on the injection needle and may disturb the magnetic field. This posed a major problem: its use, and by extension, medical practice, was severely restricted.

(解決課題) ここにおいて、本発明は、上述の如き事情を背景として
為されたものであって、その解決課題とするところは、
磁界中で行なわれる医療行為に際しても好適に用いられ
得る注射針を提供することにある。
(Problem to be solved) Here, the present invention has been made against the background of the above-mentioned circumstances, and the problem to be solved is:
It is an object of the present invention to provide an injection needle that can be suitably used even in medical procedures performed in a magnetic field.

(解決手段) そして、かかる課題を解決するために、本発明にあって
は、注射針を、非磁性セラミックスにて構成せしめたこ
とを、その特徴とするものである。
(Solution Means) In order to solve this problem, the present invention is characterized in that the injection needle is made of non-magnetic ceramics.

また、かかるセラミックス製注射針を構成する非磁性セ
ラミックスとしては、物性的に、100MPa以上の強
度と、0.5 MN/m”2以上の破壊靭性を有してい
るものが、好適に用いられることとなる。
In addition, as the non-magnetic ceramic constituting such a ceramic injection needle, one having a physical strength of 100 MPa or more and a fracture toughness of 0.5 MN/m"2 or more is preferably used. That will happen.

さらに、かかるセラミックス製注射針は、形状的に、針
部の先端傾斜角度が14±4゜、内径寸法が0.1 m
mφ以上、外径寸法が2mmφ以下であることが望まし
く、また、針部の表面が、面粗さ(Ra):1μm以下
とされていることが望ましい。
Furthermore, such a ceramic injection needle has a shape such that the needle tip has an inclination angle of 14±4° and an inner diameter of 0.1 m.
It is preferable that the outer diameter is not less than mφ and not more than 2 mmφ, and that the surface roughness (Ra) of the needle portion is preferably not more than 1 μm.

また、かかるセラミックス製注射針を構成する非磁性セ
ラミックスとしては、組織乃至は構造的に、100μm
以下の結晶平均粒子径と、5%以下の気孔率を有してい
るものが、好適に用いられるのである。
In addition, the non-magnetic ceramic constituting such a ceramic injection needle has a structure or structure of 100 μm.
Those having the following average crystal particle diameter and porosity of 5% or less are preferably used.

そして、かかるセラミックス製注射針は、一般には、ジ
ルコニア、アルミナ、ムライト、窒化珪素、炭化珪素、
サイアロン、結晶化ガラスのうち、少なくとも一つの材
料にて形成されることとなる。
Such ceramic injection needles are generally made of zirconia, alumina, mullite, silicon nitride, silicon carbide,
It is made of at least one material selected from Sialon and crystallized glass.

(発明の具体的構成) 要するに、本発明は、従来から、専ら金属材料を用いて
形成されていた注射針とは異なる技術系において好適に
用いられる、非磁性セラミックスにて構成されてなる新
規な注射針を提供するものである。
(Specific Structure of the Invention) In short, the present invention provides a novel injection needle made of non-magnetic ceramics that is suitably used in a different technical system from injection needles that have conventionally been made exclusively of metal materials. It provides injection needles.

ところで、このようなセラミックス製注射針は、ジルコ
ニアやアルミナ等の適当なセラミックス粉末に対して、
公知の手法に従い、適当なバインダーや可塑剤等を混合
して混練することにより得られたセラミックススラリー
乃至はペーストを用いて、押出成形成いは射出成形によ
りパイプ状に成形し、それを焼成せしめることによって
、セラミックス製の中空物を形成せしめた後、更に、か
かる中空物を適当な長さに切断して、その一方の端部を
ダイヤモンドカッタ等を用いて切削、研磨することによ
り、傾斜面を有する片テーパ部と為すことによって、形
成されることとなる。なお、特に、セラミックススラリ
ーの成形に際しては、船釣な中空材の押出成形手法や、
或いは中心部に線条材が埋設された中実材を押し出した
後、該線条材を除去し、焼成することによって、中空材
を得る手法等が、好適に採用されることとなる。
By the way, such ceramic injection needles are made of suitable ceramic powder such as zirconia or alumina.
Using a ceramic slurry or paste obtained by mixing and kneading appropriate binders, plasticizers, etc. according to known methods, it is formed into a pipe shape by extrusion molding or injection molding, and then fired. After forming a ceramic hollow object, the hollow object is cut to an appropriate length, and one end of the hollow object is cut and polished using a diamond cutter or the like to form an inclined surface. It is formed by forming a one-sided tapered portion having a . In particular, when molding ceramic slurry, extrusion molding methods for hollow materials,
Alternatively, a method of obtaining a hollow material by extruding a solid material with a filament embedded in the center, removing the filament, and firing the filament is preferably employed.

そして、このような本発明に従う注射針としては、使用
中における破損を防止し得るだけの機械強度を有してい
る必要があり、そのためには、IQQMPa以上、好ま
しくは200MPa以上の強度と、0.5 MN/m”
”以上、好ましくは1.0 MN/m””以上の破壊靭
性とを有する非磁性セラミックスにて構成されているこ
とが望ましい。
The injection needle according to the present invention must have a mechanical strength sufficient to prevent breakage during use, and for this purpose, it must have a strength of IQQ MPa or more, preferably 200 MPa or more, and a .5 MN/m”
It is desirable that it be made of a non-magnetic ceramic having a fracture toughness of 1.0 MN/m or higher, preferably 1.0 MN/m or higher.

また、かかるセラミックス製注射針にあっては、特に医
療用として用いられる場合、その形状が、医療分野にお
ける実際の使用性等を充分に考慮して決定されることと
なり、特に、針部の先端傾斜角(所謂、先端テーパ角)
は、皮膚への刺入性と破損防止とを考慮して、通常、1
4±4°程度に設定されることとなる。また、針部先端
の血管への刺入を容易とするために、針部先端側に向か
って段階的に若しくは連続的に変化する先端傾斜角をも
って、針部先端を成形するようにしても良い。
In addition, when such a ceramic injection needle is used for medical purposes, its shape must be determined with due consideration to actual usability in the medical field, and in particular, the shape of the needle tip Inclination angle (so-called tip taper angle)
Usually, 1.
It will be set at about 4±4°. Further, in order to facilitate the insertion of the needle tip into a blood vessel, the needle tip may be formed with a tip inclination angle that changes stepwise or continuously toward the needle tip side. .

更にまた、このように医療用に用いられる場合、注射針
における内径寸法は、薬液等の良好なる流通性を確保す
るために、0.1 mmφ以上とすることが望ましく、
且つ、血管等を傷めないように、その外径寸法は、2n
+n+φ以下とすることが望ましい。
Furthermore, when used for medical purposes in this way, the inner diameter of the injection needle is preferably 0.1 mmφ or more in order to ensure good flowability of the drug solution, etc.
In addition, its outer diameter is 2n in order to avoid damaging blood vessels, etc.
It is desirable to set it to below +n+φ.

さらに、かかる注射針の外側表面の粗さは、その使用上
、小さい程好ましく、一般には、表面粗さ(Ra )が
1μm以下、好ましくは0.5μm以下とされる。
Furthermore, the roughness of the outer surface of such an injection needle is preferably as small as possible for its use, and the surface roughness (Ra) is generally 1 μm or less, preferably 0.5 μm or less.

また、このような注射針を構成する非磁性セラミックス
の結晶粒子径が余りにも大きいと、脱粒の恐れがあり、
表面粗さの劣化および靭性の低下に繋がることとなるた
めに、その結晶平均粒子径を100μm以下とすること
が望ましい。更に、かかる注射針を構成する非磁性セラ
ミックスにおける強度および靭性の低下を防止するため
に、その気孔率を5%以下とすることが望ましいのであ
る。
Additionally, if the crystal grain size of the non-magnetic ceramics that make up such injection needles is too large, there is a risk of grain shedding.
Since this leads to deterioration of surface roughness and reduction of toughness, it is desirable that the average crystal particle size is 100 μm or less. Furthermore, in order to prevent a decrease in strength and toughness of the non-magnetic ceramic constituting the injection needle, it is desirable that the porosity of the non-magnetic ceramic be 5% or less.

そして、上述の如き注射針を形成するセラミックス材料
としては、例えば、ジルコニア1アルミナ、ムライト、
窒化硅素、炭化珪素、サイアロン結晶化ガラスが、好適
に用いられることとなる。
Ceramic materials for forming the above-mentioned injection needles include, for example, zirconia-1-alumina, mullite,
Silicon nitride, silicon carbide, and Sialon crystallized glass are preferably used.

また、そこにおいて、これらジルコニア、アルミナ、ム
ライト、窒化珪素、炭化珪素、サイアロン結晶化ガラス
の少なくとも一つの材料にて、注射針の少なくとも一部
を構成せしめることも可能であり、部分的に異なる材料
から成る非磁性セラミックスにて、目的とする注射針を
構成するようにしても良い。
In addition, it is also possible to construct at least a part of the injection needle with at least one material of these zirconia, alumina, mullite, silicon nitride, silicon carbide, and sialon crystallized glass, and partially different materials. The desired injection needle may be made of non-magnetic ceramics consisting of.

(実施例) 以下に、本発明をより具体的に明らかにするために、本
発明の一実施例を示すが、本発明は、かかる実施例の記
載によって、また前述した構成の具体的説明によって、
何等制限的に解釈されるものでないことは、言うまでも
ないところである。
(Example) In order to clarify the present invention more specifically, an example of the present invention will be shown below. ,
It goes without saying that this should not be interpreted in any restrictive manner.

そして、本発明には、その主旨を逸脱しない限りにおい
て、当業者の知識に基づ、き、種々なる変更、修正、改
良等が加えられ得るものであり、本発明が、また、その
ような実施形態のものをも含むものであることが、理解
されるべきである。
Furthermore, without departing from the spirit of the present invention, various changes, modifications, improvements, etc. may be made to the present invention based on the knowledge of those skilled in the art, and the present invention is capable of making such modifications. It should be understood that this also includes embodiments.

先ず、通常の手法に従い、部分安定化ジルコニア(ps
z)粉末を主原料とする押出用組成物(セラミックスス
ラリー)を調製し、それを押出法にて成形することによ
ってパイプ状の成形体となした。そして、かかる成形体
を焼成し、焼結せしめることによって、外径が0.7 
mmφ、内径が0,4mmφの中空体を得た。その後、
更に、かかる中空体を適当な長さに切断し、その一端側
開口部をダイヤモンドカッタにて切削、研磨することに
より、テーパ部を形成せしめた。
First, partially stabilized zirconia (ps
z) An extrusion composition (ceramics slurry) containing powder as the main raw material was prepared, and it was molded by extrusion to form a pipe-shaped molded body. Then, by firing and sintering this molded body, the outer diameter becomes 0.7
A hollow body with an inner diameter of 0.4 mmφ was obtained. after that,
Further, the hollow body was cut to an appropriate length, and the opening at one end thereof was cut and polished using a diamond cutter to form a tapered portion.

このような手法により、第1図及び第2図に示されてい
る如き、長さ(n)が50mmで、先端テーパ部2の傾
斜角(α)が14°である、目的とする、非磁性材料に
て形成されて成る医療用注射針4を、良好に得ることが
出来た。なお、図中、6は、薬液等の流通路とされる内
孔である。
By such a method, as shown in FIGS. 1 and 2, a target non-contact material having a length (n) of 50 mm and an inclination angle (α) of the tip tapered portion 2 of 14° is obtained. A medical injection needle 4 made of a magnetic material was successfully obtained. In addition, in the figure, 6 is an inner hole used as a flow path for a chemical solution or the like.

そして、かかる医療用注射針4にあっては、強力な磁界
中においても磁化されることがなく、また磁界を乱すよ
うなこともなく、医療行為に対して有利に供され得るも
のであった。
The medical injection needle 4 is not magnetized even in a strong magnetic field and does not disturb the magnetic field, so it can be advantageously used for medical treatment. .

なお、本実施例では、医療用注射針の具体例を示したが
、医療用以外の用途に用いられる注射針に対しても、本
発明が適用され得るものであることは、言うまでもない
ところである。
Although this example shows a specific example of a medical injection needle, it goes without saying that the present invention can also be applied to injection needles used for purposes other than medical purposes. .

(発明の効果) 以上の説明から明らかなように、本発明に従えば、強力
な磁界中でも良好に使用され得る注射針が、有利に実現
され得るのであり、それによって、そのような磁界中に
おいて実施される各種の産業技術分野における操作や作
業等の範囲、特に医療行為の範囲が、極めて有利に拡大
され得ることとなるのである。
(Effects of the Invention) As is clear from the above description, according to the present invention, an injection needle that can be used satisfactorily even in a strong magnetic field can be advantageously realized. The scope of operations and work performed in various industrial technology fields, especially the scope of medical practice, can be expanded extremely advantageously.

また、本発明に係る注射針にあっては、非磁性材料とし
て、特に、セラミックスを用いたことから、従来から用
いられている金属製の注射針に比して、充分な機械的強
度および良好なる取扱性を確保しつつ、安定した非磁性
特性が得られると共に、特に医療分野に用いられる注射
針に適用した場合、人体に対してなじみ性が良く、患者
等に与える苦痛を増大させるようなこともないという、
実用上の大きな利点を有しているのである。
In addition, since the injection needle according to the present invention uses ceramics as the non-magnetic material, it has sufficient mechanical strength and good properties compared to conventionally used metal injection needles. It provides stable non-magnetic properties while ensuring easy handling, and is particularly compatible with the human body when applied to injection needles used in the medical field, making it difficult to avoid causing pain to patients. There is no such thing as
It has great practical advantages.

【図面の簡単な説明】[Brief explanation of the drawing]

第1図は、本発明に係る医療用セラミックス製注射針の
一具体例を示す説明図であり、第2図は、第1図におけ
る■−■断面図である。 2:先端テーパ部    4:注射針 6:内孔 ■
FIG. 1 is an explanatory view showing a specific example of a medical ceramic injection needle according to the present invention, and FIG. 2 is a cross-sectional view taken along the line -■ in FIG. 2: Tapered tip 4: Syringe needle 6: Inner hole ■

Claims (6)

【特許請求の範囲】[Claims] (1)非磁性セラミックスにて構成されていることを特
徴とするセラミックス製注射針。
(1) A ceramic injection needle characterized by being made of non-magnetic ceramics.
(2)前記非磁性セラミックスが、100MPa以上の
強度と、0.5MN/m^3^/^2以上の破壊靭性を
有している請求項(1)記載のセラミックス製注射針。
(2) The ceramic injection needle according to claim (1), wherein the non-magnetic ceramic has a strength of 100 MPa or more and a fracture toughness of 0.5 MN/m^3^/^2 or more.
(3)針部の先端傾斜角度が14±4゜、内径寸法が0
.1mmφ以上、外径寸法が2mmφ以下である請求項
(1)又は(2)に記載のセラミックス製注射針。
(3) The tip angle of the needle is 14±4°, and the inner diameter is 0.
.. The ceramic injection needle according to claim (1) or (2), which has an outer diameter of 1 mmφ or more and 2 mmφ or less.
(4)針部の表面が、面粗さ(Ra):1μm以下とさ
れている請求項(1)乃至(3)の何れかに記載のセラ
ミックス製注射針。
(4) The ceramic injection needle according to any one of claims (1) to (3), wherein the surface of the needle portion has a surface roughness (Ra) of 1 μm or less.
(5)前記非磁性セラミックスが、100μm以下の結
晶平均粒子径と、5%以下の気孔率を有している請求項
(1)乃至(4)の何れかに記載のセラミックス製注射
針。
(5) The ceramic injection needle according to any one of claims (1) to (4), wherein the non-magnetic ceramic has an average crystal grain size of 100 μm or less and a porosity of 5% or less.
(6)ジルコニア、アルミナ、ムライト、窒化珪素、炭
化珪素、サイアロン、結晶化ガラスのうち、少なくとも
一つの材料にて形成されている請求項(1)乃至(5)
の何れかに記載のセラミックス製注射針。
(6) Claims (1) to (5) made of at least one material selected from zirconia, alumina, mullite, silicon nitride, silicon carbide, sialon, and crystallized glass.
The ceramic injection needle according to any of the above.
JP2086788A 1990-03-30 1990-03-30 Injection needle made of ceramics Pending JPH03284264A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2086788A JPH03284264A (en) 1990-03-30 1990-03-30 Injection needle made of ceramics

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2086788A JPH03284264A (en) 1990-03-30 1990-03-30 Injection needle made of ceramics

Publications (1)

Publication Number Publication Date
JPH03284264A true JPH03284264A (en) 1991-12-13

Family

ID=13896503

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2086788A Pending JPH03284264A (en) 1990-03-30 1990-03-30 Injection needle made of ceramics

Country Status (1)

Country Link
JP (1) JPH03284264A (en)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0716297A (en) * 1993-06-30 1995-01-20 Kazuji Takemoto Medical needle
EP0747333A1 (en) * 1995-06-06 1996-12-11 Ngk Insulators, Ltd. Method for producing cylindrical ceramic body
GB2304580A (en) * 1995-08-31 1997-03-26 Jocelyn Asher Simon Brookes Magnetic resonance-compatible needle
US5730732A (en) * 1996-12-04 1998-03-24 Ethicon, Inc. Non-magnetic stainless steel surgical needle
JP2002085413A (en) * 2000-09-14 2002-03-26 Seitai Kagaku Kenkyusho:Kk Tissue nondestructive needle and apparatus for collecting tissue
US6883552B2 (en) * 2001-12-27 2005-04-26 Terumo Kabushiki Kaisha Metal tube and its production method
US6915821B2 (en) * 2001-10-31 2005-07-12 Terumo Kabushiki Kaisha Metal tube and its production method
WO2005115505A1 (en) * 2004-05-31 2005-12-08 Institute Of Whole Body Metabolism Hollow needle and indwelling needle using the hollow needle
WO2009047490A3 (en) * 2007-10-08 2009-11-26 Renishaw Plc Catheter
WO2010007664A1 (en) * 2008-07-15 2010-01-21 佐藤製薬株式会社 Injection needle for otological use
WO2017209311A1 (en) * 2016-06-03 2017-12-07 国立大学法人東北大学 Drug solution injection device

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JPS58130051A (en) * 1982-01-28 1983-08-03 中川 秀一 Syringe needle
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JPS58130049A (en) * 1982-01-28 1983-08-03 中川 秀一 Syringe needle
JPS58130051A (en) * 1982-01-28 1983-08-03 中川 秀一 Syringe needle
JPH03193061A (en) * 1989-12-22 1991-08-22 Takeda Chem Ind Ltd Piercing needle made of ceramics

Cited By (17)

* Cited by examiner, † Cited by third party
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JPH0716297A (en) * 1993-06-30 1995-01-20 Kazuji Takemoto Medical needle
EP0747333A1 (en) * 1995-06-06 1996-12-11 Ngk Insulators, Ltd. Method for producing cylindrical ceramic body
GB2304580A (en) * 1995-08-31 1997-03-26 Jocelyn Asher Simon Brookes Magnetic resonance-compatible needle
US5730732A (en) * 1996-12-04 1998-03-24 Ethicon, Inc. Non-magnetic stainless steel surgical needle
EP0846443A1 (en) 1996-12-04 1998-06-10 Ethicon, Inc. Non-magnetic stainless steel surgical needle
JP2002085413A (en) * 2000-09-14 2002-03-26 Seitai Kagaku Kenkyusho:Kk Tissue nondestructive needle and apparatus for collecting tissue
US7104103B2 (en) 2001-10-31 2006-09-12 Terumo Kabushiki Kaisha Method for producing a metal tube
US6915821B2 (en) * 2001-10-31 2005-07-12 Terumo Kabushiki Kaisha Metal tube and its production method
US6883552B2 (en) * 2001-12-27 2005-04-26 Terumo Kabushiki Kaisha Metal tube and its production method
US7082795B2 (en) 2001-12-27 2006-08-01 Terumo Kabushiki Kaisha Metal tube and its production method
WO2005115505A1 (en) * 2004-05-31 2005-12-08 Institute Of Whole Body Metabolism Hollow needle and indwelling needle using the hollow needle
JPWO2005115505A1 (en) * 2004-05-31 2008-03-27 株式会社生体科学研究所 Hollow needle and indwelling needle using the hollow needle
WO2009047490A3 (en) * 2007-10-08 2009-11-26 Renishaw Plc Catheter
WO2010007664A1 (en) * 2008-07-15 2010-01-21 佐藤製薬株式会社 Injection needle for otological use
JP5215394B2 (en) * 2008-07-15 2013-06-19 佐藤製薬株式会社 Otolaryngological needle
WO2017209311A1 (en) * 2016-06-03 2017-12-07 国立大学法人東北大学 Drug solution injection device
JPWO2017209311A1 (en) * 2016-06-03 2019-04-11 国立大学法人東北大学 Chemical injection device

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