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JPH0246565B2 - - Google Patents

Info

Publication number
JPH0246565B2
JPH0246565B2 JP61154285A JP15428586A JPH0246565B2 JP H0246565 B2 JPH0246565 B2 JP H0246565B2 JP 61154285 A JP61154285 A JP 61154285A JP 15428586 A JP15428586 A JP 15428586A JP H0246565 B2 JPH0246565 B2 JP H0246565B2
Authority
JP
Japan
Prior art keywords
compound
acid
water
thiazolyl
whole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP61154285A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6226222A (ja
Inventor
Eemu Rune
Ryutsutsu Andore
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of JPS6226222A publication Critical patent/JPS6226222A/ja
Publication of JPH0246565B2 publication Critical patent/JPH0246565B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Paints Or Removers (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP61154285A 1976-01-23 1986-07-02 細菌性感染症治療剤 Granted JPS6226222A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR76-01834 1976-01-23
FR7601834A FR2346014A1 (fr) 1976-01-23 1976-01-23 Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR76-17743 1976-06-11
FR76-25051 1976-08-18

Publications (2)

Publication Number Publication Date
JPS6226222A JPS6226222A (ja) 1987-02-04
JPH0246565B2 true JPH0246565B2 (pl) 1990-10-16

Family

ID=9168296

Family Applications (7)

Application Number Title Priority Date Filing Date
JP3097080A Granted JPS55147290A (en) 1976-01-23 1980-03-13 Novel oxime derivative of 77aminothiazolylacetamidocephalosporanic acid* its manufacture and pharmaceutic composition
JP56119432A Granted JPS5762288A (en) 1976-01-23 1981-07-31 Novel oxime derivative of 7-aminothiazolylacetamidocephalosporanic acid, manufacture and pharmaceutical composition
JP59202156A Pending JPS60105670A (ja) 1976-01-23 1984-09-28 アミノチアゾリル酢酸の新規なオキシム誘導体
JP61154285A Granted JPS6226222A (ja) 1976-01-23 1986-07-02 細菌性感染症治療剤
JP61154284A Granted JPS6230787A (ja) 1976-01-23 1986-07-02 ７−アミノチアゾリルアセトアミドセフアロスポラン酸の新規なオキシム誘導体
JP62005195A Pending JPS62181248A (ja) 1976-01-23 1987-01-14 ２−（２−アミノチアゾリル）−２−ヒドロキシイミノ酢酸誘導体及びその製造法
JP62130077A Granted JPS6339869A (ja) 1976-01-23 1987-05-28 アミノチアゾリル酢酸の新規なオキシム誘導体及びその製造法

Family Applications Before (3)

Application Number Title Priority Date Filing Date
JP3097080A Granted JPS55147290A (en) 1976-01-23 1980-03-13 Novel oxime derivative of 77aminothiazolylacetamidocephalosporanic acid* its manufacture and pharmaceutic composition
JP56119432A Granted JPS5762288A (en) 1976-01-23 1981-07-31 Novel oxime derivative of 7-aminothiazolylacetamidocephalosporanic acid, manufacture and pharmaceutical composition
JP59202156A Pending JPS60105670A (ja) 1976-01-23 1984-09-28 アミノチアゾリル酢酸の新規なオキシム誘導体

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP61154284A Granted JPS6230787A (ja) 1976-01-23 1986-07-02 ７−アミノチアゾリルアセトアミドセフアロスポラン酸の新規なオキシム誘導体
JP62005195A Pending JPS62181248A (ja) 1976-01-23 1987-01-14 ２−（２−アミノチアゾリル）−２−ヒドロキシイミノ酢酸誘導体及びその製造法
JP62130077A Granted JPS6339869A (ja) 1976-01-23 1987-05-28 アミノチアゾリル酢酸の新規なオキシム誘導体及びその製造法

Country Status (5)

Country Link
JP (7) JPS55147290A (pl)
FR (1) FR2346014A1 (pl)
GT (1) GT198172848A (pl)
PL (1) PL122968B1 (pl)
ZA (1) ZA77136B (pl)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2408613A2 (fr) * 1977-07-19 1979-06-08 Roussel Uclaf Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
DK162391C (da) * 1976-04-12 1992-03-09 Fujisawa Pharmaceutical Co Analogifremgangsmaade til fremstilling af syn-isomerer af 3,7-disubstituerede 3-cephem-4-carboxylsyreforbindelser
DE2760484C2 (pl) * 1976-04-14 1992-12-03 Takeda Chemical Industries, Ltd., Osaka, Jp
JPS6011713B2 (ja) * 1976-09-08 1985-03-27 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
FR2399418A1 (fr) * 1977-03-14 1979-03-02 Fujisawa Pharmaceutical Co Procede de preparation d'acides iminoacetiques et nouveaux produits ainsi obtenus, utilises pour la synthese d'acides cepham- ou cephem-carboxyliques
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
FR2444032A2 (fr) * 1978-12-13 1980-07-11 Roussel Uclaf Nouveaux produits derives de l'acide 2-(2-tritylamino-4-thiazolyl) acetique et leur procede de preparation
FR2445830A1 (fr) * 1979-01-05 1980-08-01 Roussel Uclaf Nouveaux derives de l'acide (4-thiazolyl) acetique procede de preparation
FR2475545A1 (fr) * 1980-02-12 1981-08-14 Rhone Poulenc Ind Nouveaux thioloesters, leur preparation et leur utilisation en synthese
FR2475043A2 (fr) * 1980-02-06 1981-08-07 Roussel Uclaf Nouvelles oximes derivees de l'acide 2-(2-amino protege 4-thiazolyl) acetique, leur procede de preparation et leur application
NL8100539A (nl) 1980-02-12 1981-09-01 Rhone Poulenc Ind Nieuwe thiolesters, de bereiding daarvan en hun gebruik bij syntheses.
FR2482594A2 (fr) * 1980-05-13 1981-11-20 Rhone Poulenc Ind Nouveaux thioloesters, leur preparation et leur utilisation en synthese
IL63965A (en) * 1980-10-10 1985-01-31 Sparamedica Ag 7-(2-(2-amino-4-selenazoyl)acetamido)cephalosporin derivatives,and intermediates therefor,their preparation and pharmaceutical compositions containing them
JPS61171464A (ja) * 1985-01-23 1986-08-02 Dai Ichi Seiyaku Co Ltd オキシイミノ酪酸誘導体の製法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1536281A (en) * 1975-06-09 1978-12-20 Takeda Chemical Industries Ltd Cephem compounds

Also Published As

Publication number Publication date
JPS60105670A (ja) 1985-06-11
JPS55147290A (en) 1980-11-17
JPH0246596B2 (pl) 1990-10-16
JPS6226222A (ja) 1987-02-04
JPS62181248A (ja) 1987-08-08
GT198172848A (es) 1983-06-08
JPS638107B2 (pl) 1988-02-19
ZA77136B (en) 1978-02-22
JPS5762288A (en) 1982-04-15
JPS6230787A (ja) 1987-02-09
JPH0419229B2 (pl) 1992-03-30
FR2346014A1 (fr) 1977-10-28
FR2346014B1 (pl) 1979-10-05
PL122968B1 (en) 1982-09-30
JPS6339869A (ja) 1988-02-20
JPS638117B2 (pl) 1988-02-19

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