JP7598212B2 - Electrospinning composition for deodorization - Google Patents

Description

The present invention relates to a deodorizing technology that utilizes fiber deposits produced by electrospinning.

Various methods for forming fiber deposits by electrospinning are known, and as a technology that utilizes such a method for deodorization, Patent Document 1 discloses an ultrafine fiber laminate in which a deodorant is exposed on the surface of ultrafine fibers or encapsulated within ultrafine fibers, which is produced by dispersing a deodorant in a water-soluble polymer aqueous solution and spraying it by an electrospinning method. Meanwhile, Patent Document 2 discloses a method for forming a coating containing fibers with excellent adhesion on the surface of the skin or nail by dissolving a water-insoluble polymer in a solvent of volatile alcohol or ketone and water, and electrospinning it directly onto human skin or nail.

JP 2019-44282 A JP 2018-177803 A

The technology described in the cited document 1 uses only water as a solvent and a water-soluble polymer, so when a textile laminate is formed on the surface of the human body, such as human skin, it takes a long time to dry and the textile laminate is dissolved by the moisture released from the human body due to sweating, etc., which is a problem. In addition, the technology described in the cited document 2 does not take into consideration its application to deodorizing technology, and does not suggest any conditions for incorporating a deodorant.

The present invention therefore relates to a composition and method for forming a fiber deposit using electrostatic spinning that has deodorizing properties and is not easily dissolved by moisture such as sweat when applied to the surface of the human body.

The inventors conducted various studies and discovered that by using a water-insoluble polymer, using a volatile alcohol or ketone and water as a solvent, containing a water-insoluble deodorant in a certain ratio, and discharging this composition from an electrostatic spinning device onto the surface of the human body to form a coating containing fibers, or by discharging the composition on a place other than the surface of the human body and applying the formed sheet containing fibers to the surface of the human body, it is possible to obtain a coating or sheet that is resistant to dissolution by moisture such as sweat, has good adhesion to the skin, etc., and has deodorizing properties, and thus completed the present invention.

The present invention provides a composition X used for producing a fiber deposit by being discharged from an electrostatic spinning apparatus, the composition X comprising the following components (a) to (d), in which the mass ratio (d)/(b) of component (d) to component (b) is 0.01 or more and 0.9 or less:
(a) One or more volatile substances selected from alcohols and ketones.
(b) a water-insoluble polymer that is soluble in component (a);
(c) Water
(d) one or more water-soluble deodorizing components selected from polyhydroxyamines, polyethyleneimines, alkanolamines, basic amino acids or their polymers, and alkali metal phosphates;

The present invention also provides a method for forming a fiber-containing coating on the surface of a human body by electrostatically spinning a composition X containing the following components (a) to (d) onto the surface of the human body, wherein the mass ratio (d)/(b) of component (d) to component (b) is 0.01 or more and 0.9 or less:
(a) One or more volatile substances selected from alcohols and ketones.
(b) a water-insoluble polymer that is soluble in component (a);
(c) Water
(d) one or more water-soluble deodorizing components selected from polyhydroxyamines, polyethyleneimines, alkanolamines, basic amino acids or their polymers, and alkali metal phosphates;

The present invention further provides a method for deodorizing malodor emitted from the human body by electrostatically spinning a composition X containing the following components (a) to (d) onto the surface of the human body to form a coating containing fibers on the surface of the human body, wherein the mass ratio (d)/(b) of component (d) to component (b) is 0.01 or more and 0.9 or less.
(a) One or more volatile substances selected from alcohols and ketones.
(b) a water-insoluble polymer that is soluble in component (a);
(c) Water
(d) one or more water-soluble deodorizing components selected from polyhydroxyamines, polyethyleneimines, alkanolamines, basic amino acids or their polymers, and alkali metal phosphates;

The present invention further relates to the following components (B) and (d):
(B) Water-insoluble polymer
(d) A sheet for application to the surface of the human body comprising fibers containing one or more water-soluble deodorizing components selected from polyhydroxyamine, polyethyleneimine, alkanolamine, basic amino acid or a polymer thereof, and alkali metal phosphate, wherein the mass ratio (d)/(B) of component (d) to component (B) is 0.01 or more and 0.9 or less, the basis weight is 0.05 g/m2 or ^more and 50 g/m2 ^or less, and the equivalent circle diameter of the fibers is 100 nm or more and 15,000 nm or less.

According to the present invention, by forming a coating containing fibers containing a deodorant on the surface of the human body using electrostatic spinning, or by applying a sheet containing fibers formed on a place other than the surface of the human body to the surface of the human body, the coating or sheet has good adhesion to the surface of the human body and has deodorizing properties, allowing the deodorizing properties to be sustained.

FIG. 1 is a schematic diagram showing the configuration of an electrospinning device preferably used in the present invention. FIG. 2 is a schematic diagram showing the configuration of another embodiment of an electrospinning apparatus suitably used in the present invention. 3 is a schematic diagram showing the structure of a cartridge unit and a main body unit provided in the electrospinning apparatus shown in FIG. 2. 3 is a schematic diagram showing another embodiment of the cartridge unit and the main body unit provided in the electrospinning apparatus shown in FIG. 2. FIG. 1 is a schematic diagram showing the configuration of yet another embodiment of an electrospinning apparatus used in the present invention. FIG. 6 is a schematic diagram showing the structure of a cartridge unit provided in the electrospinning apparatus shown in FIG. 5 . FIG. 1 is a schematic diagram showing a state in which an electrostatic spinning method is performed using an electrostatic spinning device.

[Component (a): Volatile substances]
The volatile substance of component (a) used in the composition X for electrostatic spinning of the present invention is one or more selected from alcohols and ketones, and is a substance that has volatility in a liquid state. After the composition X placed in an electric field is sufficiently charged, it is discharged from the tip of a nozzle toward a flat surface, and as the component (a) evaporates, the charge density of the composition X becomes excessive, and the component (a) further evaporates while being further finely divided by Coulomb repulsion, and finally a dry fiber deposit can be formed. For this purpose, the vapor pressure of the volatile substance at 20°C is preferably 0.01 kPa to 106.66 kPa, more preferably 0.13 kPa to 66.66 kPa, even more preferably 0.67 kPa to 40.00 kPa, and even more preferably 1.33 kPa to 40.00 kPa.

Of the volatile substances of component (a), suitable alcohols include, for example, monohydric chain aliphatic alcohols, monohydric cyclic aliphatic alcohols, and monohydric aromatic alcohols. As monohydric chain aliphatic alcohols, those having 1 to 6 carbon atoms are preferred, and examples thereof include ethanol, 1-propanol, 2-propanol, butanol, and pentanol. As monohydric cyclic aliphatic alcohols, those having 4 to 6 carbon atoms are preferred, and examples of monohydric aromatic alcohols include benzyl alcohol and phenylethyl alcohol.

Among the volatile substances of component (a), the ketone is preferably a dialkyl ketone in which the alkyl group has 1 to 4 carbon atoms, such as acetone, methyl ethyl ketone, and methyl isobutyl ketone.

The volatile substance of component (a) may be one or more of the following: more preferably one or more selected from ethanol, isopropyl alcohol, and butyl alcohol; even more preferably one or two selected from ethanol and butyl alcohol; and from the viewpoint of the feel of the formed fiber, it is even more preferable that it contains ethanol.

The content of component (a) in composition X is preferably 65% by mass or more, more preferably 67% by mass or more, even more preferably 68% by mass or more, and even more preferably 69% by mass or more. It is also preferably 90% by mass or less, more preferably 88% by mass or less, even more preferably 85% by mass or less, and even more preferably 80% by mass or less. The content of component (a) in composition X is preferably 65% by mass or more and 90% by mass or less, more preferably 67% by mass or more and 88% by mass or less, even more preferably 68% by mass or more and 85% by mass or less, and even more preferably 69% by mass or more and 80% by mass or less. By including component (a) in composition X in this ratio, component (a) can be sufficiently volatilized during electrostatic spinning, and a fiber deposit can be formed.

In addition, from the viewpoint of high volatility and the feel of the formed fiber, the amount of ethanol is preferably 50% by mass or more and 100% by mass or less, more preferably 65% by mass or more and 100% by mass or less, and even more preferably 80% by mass or more and 100% by mass or less, based on the total amount of volatile substances in component (a).

[Component (b): Water-insoluble polymer]
The water-insoluble polymer, component (b), is a substance that can be dissolved in the volatile substance, component (a). Here, "dissolved" means that the polymer is in a dispersed state at 20°C, and the dispersed state is visually uniform, preferably visually transparent or translucent.

As the water-insoluble polymer, an appropriate one is used depending on the properties of the volatile substance of component (a). Specifically, it is a polymer that is soluble in component (a) and insoluble in water, and has fiber-forming ability. In this specification, the term "water-soluble polymer" refers to a polymer that has the property that 1 g of the polymer is weighed out and immersed in 10 g of ion-exchanged water under an environment of 1 atmosphere and 23°C, and after 24 hours, 0.5 g or more of the immersed polymer dissolves in water. On the other hand, in this specification, the term "water-insoluble polymer" refers to a polymer that has the property that 1 g of the polymer is weighed out and immersed in 10 g of ion-exchanged water under an environment of 1 atmosphere and 23°C, and after 24 hours, 0.5 g or more of the immersed polymer does not dissolve, in other words, a polymer that has the property that the amount of dissolution is less than 0.5 g.

Examples of water-insoluble polymers capable of forming fibers include fully saponified polyvinyl alcohol, which can be insolubilized after the formation of fiber deposits, partially saponified polyvinyl alcohol, which can be crosslinked after the formation of fiber deposits by using a crosslinking agent in combination, oxazoline-modified silicones such as poly(N-propanoylethyleneimine) graft-dimethylsiloxane/γ-aminopropylmethylsiloxane copolymers, polyvinyl acetal diethylaminoacetate, zein (the main component of corn protein), polyesters, polylactic acid (PLA), acrylic resins such as polyacrylonitrile resins and polymethacrylic acid resins, polystyrene resins, polyvinyl butyral resins, polyethylene terephthalate resins, polybutylene terephthalate resins, polyurethane resins, polyamide resins, polyimide resins, and polyamideimide resins. One or more of these water-insoluble polymers can be used in combination. Of these water-insoluble polymers, it is preferable to use one or more selected from fully saponified polyvinyl alcohol, which can be insolubilized after the formation of a fiber deposit; partially saponified polyvinyl alcohol, which can be crosslinked after the formation of a fiber deposit by using a crosslinking agent in combination; acrylic resins such as polyvinyl butyral resin, polyurethane resin, and polymethacrylic acid resin; oxazoline-modified silicones such as poly(N-propanoylethyleneimine) graft-dimethylsiloxane/γ-aminopropylmethylsiloxane copolymer; polylactic acid (PLA); and zein.

Among these water-insoluble polymers, from the viewpoints of dispersibility in alcohol solvents and the feel of the fibers, one or more selected from partially saponified polyvinyl alcohol, fully saponified polyvinyl alcohol, polyvinyl butyral resin, polymethacrylic resin, and polyurethane resin are more preferable, and one or more selected from partially saponified polyvinyl alcohol, fully saponified polyvinyl alcohol, and polyvinyl butyral resin are even more preferable, and polyvinyl butyral resin is even more preferable from the viewpoints of the stable and efficient formation of fiber deposits, and the compatibility between the durability, formability, and conformability to the human body surface, etc., of the fiber deposits.

The content of component (b) in composition X is preferably 3% by mass or more, more preferably 4% by mass or more, even more preferably 5% by mass or more, and even more preferably 8% by mass or more. It is also preferably 25% by mass or less, more preferably 20% by mass or less, even more preferably 15% by mass or less, and even more preferably 12% by mass or less. The content of component (b) in composition X is preferably 3% by mass or more and 25% by mass or less, more preferably 4% by mass or more and 20% by mass or less, even more preferably 5% by mass or more and 15% by mass or less, and even more preferably 8% by mass or more and 12% by mass or less. By including component (b) in composition X in this ratio, a fiber deposit can be formed stably and efficiently.

The ratio (b)/(a) of the content of component (b) to component (a) in composition X is preferably 0.02 to 0.20, more preferably 0.03 to 0.18, even more preferably 0.04 to 0.16, and even more preferably 0.06 to 0.14, in order to sufficiently volatilize component (a) such as ethanol during electrostatic spinning and stably form fiber deposits. Note that, even when component (a) is ethanol only, the mass ratio (b)/(a) is similarly preferably 0.02 to 0.20, more preferably 0.03 to 0.18, even more preferably 0.04 to 0.16, and even more preferably 0.05 to 0.14.

[Component (c): Water]
Component (c) is water. Compared with non-ionizing solvents such as ethanol, water is ionized and charged, and therefore can impart electrical conductivity to composition X. Therefore, fiber deposits are stably formed by electrostatic spinning. In addition, water contributes to improving the adhesion of fiber deposits formed by electrostatic spinning to the surface of the human body, improving durability, and improving the appearance. From the viewpoint of obtaining these effects, the content of component (c) in composition X is preferably 6% by mass or more, more preferably 8% by mass or more, and even more preferably 10% by mass or more. In addition, the content of component (c) in composition X is preferably 24% by mass or less, more preferably 22% by mass or less, and from the viewpoint of ensuring the formability of fiber deposits even in summer or in a humid environment, it is preferably 20% by mass or less. The content of water in composition X is preferably 6% by mass or more and 24% by mass or less, more preferably 8% by mass or more and 22% by mass or less, and even more preferably 10% by mass or more and 20% by mass or less, from the viewpoint of forming fiber deposits even in a humid environment.

In addition, from the viewpoint of stably dissolving sufficient amounts of both the water-soluble deodorant component and the water-insoluble polymer in composition X, the mass ratio (b)/(c) of component (b) to component (c) is preferably 0.22 or more, more preferably 0.23 or more, and even more preferably 0.25 or more. The mass ratio (b)/(c) is preferably 3 or less, more preferably 2 or less, and even more preferably 1 or less. The range of the mass ratio (b)/(c) is preferably 0.22 or more and 3 or less, more preferably 0.23 or more and 2 or less, and even more preferably 0.25 or more and 1 or less.

In addition, from the viewpoint of obtaining a stable fiber deposit by electrostatic spinning of composition X, and improving the adhesion and durability of the obtained fiber deposit, the mass ratio (a)/(c) of component (a) to component (c) is preferably 3 or more, and more preferably 3.5 or more. The mass ratio (a)/(c) is preferably 10 or less, more preferably 9.0 or less, and even more preferably 8.0 or less. The range of the mass ratio (a)/(c) is preferably 3 or more and 10 or less, more preferably 3 or more and 9.0 or less, and even more preferably 3.5 or more and 8.0 or less. Similarly, when component (a) is ethanol, the mass ratio (a)/(c) of component (a) to component (c) is preferably 3 or more and 10 or less, more preferably 3 or more and 9.0 or less, and even more preferably 3.5 or more and 8.0 or less.

[Component (d): Water-soluble deodorant component]
Component (d) is a water-soluble deodorant component, which has a fiber-forming ability in combination with component (b). In this specification, "water-soluble" refers to the property that, in an environment of 1 atmospheric pressure and 23°C, 1 g of the component is weighed out and then immersed in 10 g of ion-exchanged water, and after 24 hours, 0.5 g or more of the immersed component dissolves in water.

The water-soluble deodorizing component of component (d) is selected from polyhydroxyamines, polyethyleneimines, alkanolamines, basic amino acids or their polymers, and alkali metal phosphates. Examples of polyhydroxyamines include tris(hydroxymethyl)aminomethane (also known as 2-amino-2-hydroxymethyl-1,3-propanediol), 2-amino-1,3-propanediol, 2-amino-2-methyl-1,3-propanediol, 2-amino-2-ethyl-1,3-propanediol, 2-amino-2-hydroxyethyl-1,3-propanediol, 4-amino-4-hydroxypropyl-1,7-heptanediol, 2-(N-ethyl)amino-1,3-propanediol, 2-(N-ethyl)amino-2-hydroxymethyl-1,3-propanediol, 2-(N-decyl)amino-1,3-propanediol, and 2-(N-decyl)amino-2-hydroxymethyl-1,3-propanediol. Examples of polyethyleneimines include those having a molecular weight of 300 to 100,000, preferably those having a molecular weight of 1,000 to 35,000, more preferably those having a molecular weight of 1,500 to 20,000, and even more preferably those having a molecular weight of 5,000 to 15,000. Examples of alkanolamines include monoethanolamine, isopropanolamine, 2-amino-2-methylpropanol, 2-aminobutanol, and trishydroxymethylaminomethane. Examples of basic amino acids or polymers thereof include arginine, histidine, lysine, ornithine, and polylysine. Examples of alkali metal phosphates include disodium hydrogen phosphate, dipotassium hydrogen phosphate, sodium dihydrogen phosphate, and potassium dihydrogen phosphate.

From the viewpoint of improving the deodorizing effect, the content of component (d) in composition X is preferably 0.1% by mass or more, more preferably 0.2% by mass or more, even more preferably 0.5% by mass or more, and even more preferably 1.0% by mass or more. From the viewpoint of the stability of the formed coating, it is preferably 10% by mass or less, more preferably 5% by mass or less, even more preferably 4% by mass or less, and even more preferably 3% by mass or less. The content of component (d) in composition X is preferably 0.1% by mass or more and 10% by mass or less, more preferably 0.2% by mass or more and 5% by mass or less, even more preferably 0.3% by mass or more and 4% by mass or less, and even more preferably 0.5% by mass or more and 3% by mass or less.

The mass ratio (d)/(b) of component (d) to component (b) is 0.01 or more, preferably 0.02 or more, more preferably 0.04 or more, and even more preferably 0.1 or more, from the viewpoint of improving the deodorizing effect, and from the viewpoint of ease of discharge from the electrostatic spinning device and suppressing adhesion between the formed fibers to form a laminated state with a high surface area, it is 0.9 or less, preferably 0.8 or less, more preferably 0.7 or less, and even more preferably 0.6 or less. Note that the lower this ratio, the easier it is to discharge from the electrostatic spinning device, the better the quality of the formed fibers, and the easier it is to laminate, but the deodorizing effect per discharge amount decreases. Therefore, when the mass ratio (d)/(b) is low, the amount of discharge onto the human body surface, etc. is increased, and the basis weight of the formed coating is increased, thereby achieving both ease of discharge and deodorizing effect.

The mass ratio (d)/(c) of component (d) to component (c) is preferably 0.02 or more, more preferably 0.05 or more, and even more preferably 0.1 or more, from the viewpoint of improving the deodorizing effect, and is preferably 1.0 or less, more preferably 0.3 or less, even more preferably 0.2 or less, and even more preferably 0.15 or less, from the viewpoint of the compounding stability of composition X.

[Optional components]
Composition X may contain only the above-mentioned components (a) to (d), or may contain other components in addition to components (a) to (d). Examples of other components include polyols, pH adjusters, surfactants, liquid oils, plasticizers for the polymer of component (b), conductivity control agents for composition X, water-soluble polymers, powders such as coloring pigments and extender pigments, dyes, water-insoluble deodorants such as porous powders, fragrances, repellents, antioxidants, stabilizers, antibacterial agents, preservatives, various vitamins, etc. When composition X contains other components, the content of the other components is preferably 0.1% by mass or more and 30% by mass or less, and more preferably 0.5% by mass or more and 20% by mass or less.

Polyol From the viewpoint of improving the deodorizing effect and dissolving the component (d), it is preferable that the composition X contains a polyol. Examples of the polyol include dihydric alcohols such as dipropylene glycol, 1,3-butylene glycol, 3-methyl-1,3-butanediol, isoprene glycol, polyethylene glycol, 1,2-pentanediol, 1,2-hexanediol, propylene glycol, polypropylene glycol, ethylene glycol, diethylene glycol, and neopentyl glycol; glycerols such as glycerin, diglycerin, triglycerin, and tetraglycerin; and sugar alcohols such as sorbitol, xylitol, maltitol, and erythritol. Among them, one or more selected from polyethylene glycols and polypropylene glycols having a molecular weight of 3000 or less are preferable.

The content of polyol in composition X is preferably 0.5% by mass or more, more preferably 1% by mass or more, from the viewpoint of improving the deodorizing effect and dissolving component (d), and is preferably 10% by mass or less, more preferably 5% by mass or less, from the viewpoint of stably forming a coating on the fiber.

pH adjuster Composition X may contain a pH adjuster for pH adjustment. As the pH adjuster, organic acids, inorganic acids and their salts may be used, and organic acids and their salts are particularly preferred. Organic acids include citric acid, glycolic acid, succinic acid, tartaric acid, lactic acid, fumaric acid, malic acid, levulinic acid, butyric acid, oxalic acid, etc., and inorganic acids include hydrochloric acid, phosphoric acid, sulfuric acid, nitric acid, etc.

Composition X may contain powders such as color pigments and extender pigments, but the content of powders with a particle size of 0.1 μm or more at 20°C is preferably 1% by mass or less, more preferably 0.1% by mass or less, and even more preferably 0.01% by mass or less, from the viewpoint of the ability to form a uniform coating and the durability and adhesion of the coating, and it is preferable that no powders are contained except in cases where they are unavoidably mixed in.

〔viscosity〕
The viscosity of composition X is preferably 2 to 3000 mPa·s at 25°C from the viewpoints of stably forming a fiber deposit, spinnability during electrostatic spinning, improving the durability of the fiber deposit, and improving the feel of the fiber deposit. The viscosity is preferably 10 mPa·s or more, more preferably 15 mPa·s or more, even more preferably 20 mPa·s or more, and even more preferably 30 mPa·s or more. The viscosity is preferably 1500 mPa·s or less, more preferably 1000 mPa·s or less, and even more preferably 800 mPa·s or less. The viscosity range is preferably 2 mPa·s or more and 3000 mPa·s or less, more preferably 10 mPa·s or more and 1500 mPa·s or less, even more preferably 15 mPa·s or more and 1000 mPa·s or less, and even more preferably 15 mPa·s or more and 800 mPa·s or less. The viscosity of composition X is measured at 25° C. using an E-type viscometer. For example, an E-type viscometer (VISCONIC EMD) manufactured by Tokyo Keiki Co., Ltd. can be used as the E-type viscometer. In this case, the measurement conditions are 25° C., a cone plate rotor No. 43, and a rotation speed appropriate for the viscosity, which is 5 rpm for a viscosity of 500 mPa·s or more, 10 rpm for a viscosity of 150 mPa·s or more but less than 500 mPa·s, and 20 rpm for a viscosity less than 150 mPa·s.

[Formation of fiber deposits, target of deodorization]
In the present invention, the fiber deposit may be formed on the surface of the human body (in this case, it becomes a coating containing fibers that covers the surface of the human body), or it may be formed at a location other than the surface of the human body. As for a location other than the surface of the human body, it may be formed on a base layer having a flat surface as described below so that it can be peeled off after formation and used as a sheet to be applied to the surface of the human body, or it may be formed on the following objects so that it can be used without peeling off after formation. Hereinafter, these may be collectively referred to as the "surface to be formed on".
・Undergarments, underwear, socks, stockings, and other clothing ・Sweat pads, sanitary products, urine pads, and other absorbent products ・Shoe insoles and inner soles
·mask

When the surface to be formed is the surface of the human body, the composition X is electrostatically spun directly onto the surface of the human body to form a coating containing fibers on the surface of the human body. More specifically, the composition X is applied to an electrostatic spinning device, preferably an electrostatic spinning device that can be held by hand, or an electrostatic spinning device having an operating unit equipped with a spray nozzle that can be held by hand, to form a coating made of fibers on the surface of the human body. In the present invention, the water-soluble deodorizing component of component (d) is contained in the formed coating, so that it is possible to deodorize the malodor released from the surface of the human body. Component (d) exerts a deodorizing effect by being gradually released from the coating into moisture such as sweat from the surface of the human body, and this deodorizing effect can be maintained.

The present invention deodorizes malodor-causing substances released from the surface of the human body by chemically bonding with the water-soluble deodorizing component of component (d) contained in the coating, or by neutralizing with the water-soluble deodorizing component of component (d), thereby converting the malodor-causing substances into a substance different from the original compound. In this way, the present invention deodorizes solely by acting on the malodor-causing substances after they have been released from the surface of the human body, and does not have any effect on the human body. Here, examples of the surface of the human body include skin, mucous membranes, wounds, etc., and among these, skin is preferred, and armpits, lower legs, and buttocks are more preferred.

The odors that are the subject of deodorization in the present invention include sweat odor, armpit odor, aging odor, and odors caused by tumors and bedsores. Among the substances that cause malodors, compounds that can be neutralized with component (d) and deodorized include acidic malodorous substances such as acetic acid, butyric acid, isovaleric acid, 3-hydroxy-3-methylhexanoic acid, 3-methyl-2-hexenoic acid, 4-methyl-3-hexenoic acid, and nonanoic acid, and basic malodorous substances such as ammonia and trimethylamine. Among the substances that cause malodors, compounds that can be chemically bonded with component (d) and deodorized include aldehyde-based malodorous substances such as nonanal and nonenal, and ketone-based malodorous substances such as acetoin and diacetyl.

[Electrostatic spinning device]
Composition X is discharged by electrostatic spinning directly onto the part of the human body surface on which a fiber deposit (coating) is to be formed, or onto other target surfaces. The electrostatic spinning method includes a step of electrostatically spinning composition X onto a target surface using an electrostatic spinning device. The electrostatic spinning device basically includes a container for containing the composition, a nozzle for discharging the composition, a supply device for supplying the composition contained in the container to the nozzle, and a power source for applying a voltage to the nozzle.

Figure 1 shows a schematic diagram of an electrostatic spinning apparatus suitable for use in the present invention. The electrostatic spinning apparatus 10 shown in the figure is equipped with a low-voltage power supply 11. The low-voltage power supply 11 is capable of generating a voltage of several volts to several tens of volts. In order to increase the portability of the electrostatic spinning apparatus 10, it is preferable that the low-voltage power supply 11 is made up of one or more batteries. In addition, using a battery as the low-voltage power supply 11 has the advantage that it can be easily replaced as needed. Instead of a battery, an AC adapter or the like can also be used as the low-voltage power supply 11.

The electrospinning apparatus 10 also includes a high-voltage power supply 12. The high-voltage power supply 12 is connected to the low-voltage power supply 11 and includes an electrical circuit (not shown) that boosts the voltage generated by the low-voltage power supply 11 to a high voltage. The boost electrical circuit is generally composed of a transformer, a capacitor, a semiconductor element, etc.

The electrostatic spinning apparatus 10 further includes an auxiliary electric circuit 13. The auxiliary electric circuit 13 is interposed between the low-voltage power supply 11 and the high-voltage power supply 12 described above, and has the function of adjusting the voltage of the low-voltage power supply 11 to stably operate the high-voltage power supply 12. The auxiliary electric circuit 13 also has the function of controlling the rotation speed of a motor included in a micro gear pump 15A described later. By controlling the rotation speed of the motor, the amount of composition X supplied from a container 15 for composition X described later to the micro gear pump 15A is controlled. A switch SW is installed between the auxiliary electric circuit 13 and the low-voltage power supply 11, and the electrostatic spinning apparatus 10 can be operated/stopped by turning the switch SW on and off.

The electrostatic spinning device 10 further includes a nozzle 15. The nozzle 15 is made of various conductive materials such as metals, or non-conductive materials such as plastics, rubber, and ceramics that surround the conductive materials, and has a shape that allows composition X to be discharged from its tip. A microspace through which composition X flows is formed in the nozzle 15 along the longitudinal direction of the nozzle 15. The cross-sectional size of this microspace is preferably 100 μm or more and 2000 μm or less, and more preferably 300 μm or more and 1400 μm or less, in terms of diameter. From the same viewpoint, the flow path length of the nozzle 15 is preferably 2 mm or more and 25 mm or less, and more preferably 4 mm or more and 15 mm or less.

The nozzle 15 is connected to the micro gear pump 15A via the conduit 15B. The conduit 15B may be conductive or non-conductive. The nozzle 15 is also electrically connected to the high voltage power supply 12. This allows a high voltage to be applied to the nozzle 15. In this case, in order to prevent an excessive current from flowing when the human body directly touches the nozzle 15, the nozzle 15 and the high voltage power supply 12 are electrically connected via a current limiting resistor 19. The nozzle 15 and the high voltage power supply 12 may also be electrically connected via a conductor (not shown) such as an electrode.

The micro gear pump 15A, which is connected to the nozzle 15 via the pipe 15B, functions as a supply device that supplies the composition X contained in the container 14 to the nozzle 15. The micro gear pump 15A operates by receiving power from the low voltage power supply 11. The micro gear pump 15A is also configured to supply a predetermined amount of the composition X to the nozzle 15 under the control of the auxiliary electric circuit 13.

The micro gear pump 15A is connected to the container 14 via a flexible pipe 15C. The container 14 contains the composition X. The container 14 is preferably in the form of a replaceable cartridge. This cartridge is more preferably a refill cartridge. This cartridge is preferably a refill cartridge, and the composition X is filled in this cartridge.

From the viewpoint of achieving both the ease of handling of the electrospinning apparatus 10 and good discharge of the composition X, the volume of the storage section 15 is preferably 1 mL or more, more preferably 1.5 mL or more, even more preferably 3 mL or more, and preferably 25 mL or less, more preferably 20 mL or less, and even more preferably 15 mL or less. Specifically, the volume of the storage section 15 is preferably 1 mL or more and 25 mL or less, more preferably 1.5 mL or more and 20 mL or less, and even more preferably 3 mL or more and 15 mL or less. By having the volume of the container 15 (also referred to as the storage section 15) in such a range, when the container 15 is in a replaceable cartridge form, it has the advantage of being small and easily replaceable.

Next, another embodiment of the electrospinning device used in the present invention will be described with reference to Figures 2 to 6. The electrospinning device 10 shown in Figures 2 to 6 differs from the electrospinning device shown in Figure 1 in that it is equipped with a cartridge unit and a main body unit. For the embodiment shown in Figures 2 to 6, the description of the embodiment shown in Figure 1 applies as appropriate to points that are not specifically described. In Figures 2 to 6, the same reference numerals are used for the same members as in Figure 1.

An electrostatic spinning apparatus 10 according to an embodiment shown in FIGS. 2 and 3 will now be described.
2 and 3, the electrospinning apparatus 10 is roughly divided into a cartridge section 10A and a main body section 10B. The cartridge section 10A is provided with a storage section 14, a gasket 141, a plunger 142, and a nozzle 15. The main body section 10B is provided with a low-voltage power supply 11, a high-voltage power supply 12, an auxiliary electric circuit 13, a power source 16 including a DC motor 160 and a motor reducer 161, and a power transmission section 17 including a screw shaft 171 and a feed screw 172.

The cartridge part 10A is detachable from the main body part 10B. Due to this, according to the electrospinning device 10 of this embodiment, the composition X can be easily refilled and the nozzle 15 can be kept clean. Examples of the form in which the cartridge part 10A can be detachable from the main body part 10B include, but are not limited to, a method in which a fitting part is formed in the plunger 142 and the feed screw 172 and the fitting is performed, or a method in which a thread is formed in the plunger 142 and the feed screw 172 and the thread is screwed together.

As shown in FIG. 3, the cartridge portion 10A has a cylindrical storage portion 14 capable of storing the composition X. One end of the storage portion 14 forms an opening. The other end of the storage portion 14 is provided with a nozzle 15. A gasket 141 is disposed inside the storage portion 14. The gasket 141 has a shape having the same contour as the cross-sectional shape of the storage portion 14. This allows the gasket 141 to slide inside the storage portion 14 while being in liquid-tight contact with the inner surface of the storage portion 14. The gasket 141 is connected to the front end of the plunger 142. The plunger 142 extends beyond the opening of the storage portion 14 to the outside of the storage portion 14. The rear end of the plunger 142 engages with the feed screw 172. The storage portion 14 may be conductive or non-conductive.

In this embodiment, the nozzle 15 communicates with the storage section 14. The nozzle 15 is electrically connected to the high-voltage power supply 12. This makes it possible to apply a high voltage to the nozzle 15. In this case, in order to prevent an excessive current from flowing when the human body directly touches the nozzle 15, the nozzle 15 and the high-voltage power supply 12 are electrically connected via a current-limiting resistor 19. The nozzle 15 and the high-voltage power supply 12 may be electrically connected via a conductor (not shown) such as an electrode.

The main body 10B is equipped with a low-voltage power supply 11. The low-voltage power supply 11 is capable of generating a voltage of several volts to several tens of volts. In order to increase the portability of the electrospinning device 10, it is preferable that the low-voltage power supply 11 is made up of one or more batteries. In addition, using a battery as the low-voltage power supply 11 has the advantage that it can be easily replaced as needed. Instead of a battery, an AC adapter or the like can also be used as the low-voltage power supply 11.

The main body 10B further includes a high-voltage power supply 12. The high-voltage power supply 12 is connected to the low-voltage power supply 11 and includes an electric circuit (not shown) that boosts the voltage generated by the low-voltage power supply 11 to a high voltage. The boost electric circuit is generally composed of a transformer, a capacitor, semiconductor elements, etc.

The main body 10B further includes an auxiliary electric circuit 13. The auxiliary electric circuit 13 is interposed between the low-voltage power supply 11 and the high-voltage power supply 12 described above, and has the function of adjusting the voltage of the low-voltage power supply 11 to stably operate the high-voltage power supply 12. Furthermore, the auxiliary electric circuit 13 has the function of controlling the rotation speed of a motor included in the power source 16 described below. By controlling the rotation speed of the motor, the amount of composition X supplied from the storage section 14 in which the composition X is stored to the nozzle 15 that discharges the composition X is controlled. A switch SW is attached between the auxiliary electric circuit 13 and the low-voltage power supply 11, and the electrostatic spinning apparatus 10 can be operated/stopped by turning the switch SW on and off.

The main body 10B further includes a power source 16 and a power transmission unit 17. The power source 16 generates power to eject the composition X contained in the storage unit 14 from the nozzle 15. The power source 16 receives power from the low-voltage power source 11 and operates under the control of the auxiliary electric circuit 13. The power generated by the power source 16 is transmitted to the cartridge unit 10A by the power transmission unit 17, and is configured to supply a predetermined amount of composition X from the storage unit 14 to the nozzle 15.

The main body 10B includes a power source 16 having a DC motor 160 and a motor reducer 161, and a power transmission unit 17 having a screw shaft 171 and a feed screw 172.

The DC motor 160 is connected to a motor reducer 161 that reduces and outputs the rotational power of the DC motor 160. The motor reducer 161 is connected to a rotatable screw shaft 171, and the rotational power generated by the DC motor 160 is transmitted to the screw shaft 171 via the motor reducer 161, causing the screw shaft 171 to rotate. The rotational power transmitted to the screw shaft 171 is converted by a feed screw 172 connected to the screw shaft 171 into linear power that moves the position of the feed screw 172 along the longitudinal direction X. The linearly moving feed screw 172 pushes the plunger 142 and the gasket 141 into the storage section 14, thereby enabling the composition X contained in the storage section 14 to be sprayed to the outside through the nozzle 15.

In FIG. 3, the feed screw 172 and plunger 142 are separate, and the plunger 142 and gasket 141 are integrated. However, the feed screw 172 and plunger 142 may be integrated, and the plunger 142 and gasket 141 may be separate, or the feed screw 172 and gasket 141 may be in direct contact with each other to transmit linear power to the gasket 141.

Due to the conductive nature of the composition X used in the present invention, the high voltage applied to the nozzle 15 may be applied to the power source 16 via the composition X contained in the storage unit 14 or the power transmission unit 17, causing damage to the electrostatic spinning device 10 or leakage of electric charge, resulting in failure to spray. Therefore, in order to ensure insulation during use of the electrostatic spinning device 10 and to prevent damage to the electrostatic spinning device 10, and in order to prevent leakage of current via the composition X and ensure the stability of spinning, it is preferable that the power transmission unit 17 electrically insulates the power source 16 from the cartridge unit 10A. This effectively prevents the high voltage applied to the nozzle 15 from being unintentionally applied to the power source 16. As a method for electrically insulating the power source 16 from the cartridge unit 10A, for example, a screw shaft 171 or a feed screw 172 made of a non-conductive material such as plastic or ceramic may be used as the power transmission unit 17. As long as the power transmission section 17 electrically insulates the power source 16 from the cartridge section 10A, the gasket 141 and the plunger 142 may be conductive or non-conductive.

An electrospinning apparatus 10 according to an embodiment shown in FIG. 4 will now be described.
Figure 4 shows another embodiment of the electrospinning apparatus 10 suitable for use in the present invention. For the embodiment shown in Figure 4, the explanation of the embodiment shown in Figures 2 and 3 applies as appropriate unless otherwise specified. In Figure 4, the same members as those in Figures 2 and 3 are denoted by the same reference numerals.

As shown in FIG. 4, the cartridge unit 10A includes a storage unit 14, a gasket 141, and a nozzle 15. Meanwhile, the main body unit 10B includes a power source 16 including a linear step motor 162, and a power transmission unit 17 including a screw shaft 171. With this configuration, the amount of composition X supplied from the storage unit 14 to the nozzle 15 can be precisely controlled, and the portability of the electrospinning device 10 can be further improved due to the miniaturization of the main body unit 10B.

The linear step motor 162 has a rotor (not shown) with a female thread inside. A male-threaded screw shaft 171 is screwed into the female thread of the rotor. The linear step motor 162 is fixed to a frame (not shown) of the main body 10B. When the rotor in the linear step motor 162 rotates, the screw shaft 171 screwed into the female thread of the rotor moves linearly along the longitudinal direction X. The linearly moving screw shaft 171 pushes the gasket 141 in contact with one end of the screw shaft 171 into the storage section 14, thereby enabling the composition X stored in the storage section 14 to be sprayed to the outside through the nozzle 15.

An electrostatic spinning apparatus 10 according to an embodiment shown in FIG. 5 will be described.
Another embodiment of the electrospinning apparatus is shown in Fig. 5. The electrospinning apparatus 10 shown in the figure is roughly divided into a cartridge section 10A and a main body section 10B. The cartridge section 10A is provided with a storage section 14, a nozzle 15, and a pump section 15P. The main body section 10B is provided with a low-voltage power supply 11, a high-voltage power supply 12, an auxiliary electric circuit 13, a power source 16, and a power transmission section 17.

The cartridge part 10A is detachable from the main body part 10B. As a result, the electrostatic spinning device 10 of this embodiment allows easy refilling of the composition X and keeps the nozzle 15 clean. Examples of a form in which the cartridge part 10A can be detachable from the main body part 10B include, but are not limited to, a method in which a fitting part is formed in the power transmission part 17 described below and the pump part 15P and the power source 16 are fitted together via the power transmission part 17.

The storage unit 14 is capable of storing the composition X and is detachable from the cartridge unit 10A. Due to this, the electrostatic spinning device 10 of this embodiment makes it easier to refill the composition X. Examples of a form in which the storage unit 14 can be detachable from the cartridge unit 10A include, but are not limited to, a method in which a fitting portion is formed in the storage unit 14 and the pump unit 15P and the fitting portions are fitted together.

A cartridge portion 10A according to an embodiment shown in FIG. 6 will now be described.
FIG. 6 shows the cartridge part 10A in this embodiment. The cartridge part 10A has a bag-shaped storage part 14. The storage part 14 is formed into a flat bag shape by overlapping two sheets made of a liquid-impermeable and flexible material such as polyethylene and joining the outer edges of the sheets liquid-tightly. This gives the storage part 14 a deformable structure and allows the composition X to be stored inside the storage part 14. The storage part 14 has an opening 14a at a part of its outer edge that can communicate with the pump part 15P in order to supply the composition X to the pump part 15P. The storage part 14 may be conductive or non-conductive.

In this embodiment, the nozzle 15 communicates with the pump section 15P. The nozzle 15 is also electrically connected to the high-voltage power supply 12. This allows a high voltage to be applied to the nozzle 15. In this case, in order to prevent an excessive current from flowing when the human body directly touches the nozzle 15, the nozzle 15 and the high-voltage power supply 12 are electrically connected via a current-limiting resistor 19. The nozzle 15 and the high-voltage power supply 12 may be electrically connected via a conductor (not shown) such as an electrode. The nozzle 15 may further have a conduit that communicates with the pump section 15P. The conduit may be a conductor or a non-conductor.

The cartridge section 10A includes a pump section 15P. The pump section 15P is interposed between the storage section 14 and the nozzle 15 and communicates with each of them. The pump section 15P has a connection section 15a with the opening 14a of the storage section 14. This allows the composition X stored in the storage section 14 to be supplied to the nozzle 15 while maintaining the liquid-tightness of the flow path between the storage section 14 and the pump section 15P. The pump section 15P is driven by the power of the power source 16, which will be described later, transmitted through the power transmission section 17. The pump section 15P shown in FIG. 6 is further provided with a rotatable power transmission recess 15b for transmitting the power of the power source 16 to an internal mechanism (not shown), such as a gear, in the pump section 15P through the power transmission section 17. A gear pump or the like is used as the pump section 15P from the viewpoint of improving the discharge quantitation of the composition X and from the viewpoint of improving the portability of the electrostatic spinning device 10. As a gear pump, for example, a micro gear pump as described in the embodiment shown in FIG. 1 can be used.

Due to the fluid-tightness of the flow path between the storage section 14 and the pump section 15P, when the pump section 15P operates to eject the composition X from the storage section 14 to the nozzle 15, the amount of composition X in the storage section 14 decreases as it is supplied to the nozzle 15, and the internal pressure in the storage section 14 decreases. As a result, the storage section 14, which is made of a flexible and deformable material, deforms in a shrinking manner in response to the internal pressure.

The main body 10B is equipped with a low-voltage power supply 11. The low-voltage power supply 11 is capable of generating a voltage of several volts to several tens of volts. In order to increase the portability of the electrospinning device 10, it is preferable that the low-voltage power supply 11 is made up of one or more batteries. In addition, using a battery as the low-voltage power supply 11 has the advantage that it can be easily replaced as needed. Instead of a battery, an AC adapter or the like can also be used as the low-voltage power supply 11.

The main body 10B is equipped with a high-voltage power supply 12. The high-voltage power supply 12 is connected to the low-voltage power supply 11 and is equipped with an electric circuit (not shown) that boosts the voltage generated by the low-voltage power supply 11 to a high voltage. The boost electric circuit is generally composed of a transformer, a capacitor, semiconductor elements, etc.

The main body 10B is provided with an auxiliary electric circuit 13. The auxiliary electric circuit 13 is interposed between the low-voltage power supply 11 and the high-voltage power supply 12 described above, and has the function of adjusting the voltage of the low-voltage power supply 11 to stably operate the high-voltage power supply 12. Furthermore, the auxiliary electric circuit 13 has the function of controlling the rotation speed of a motor provided in a power source 16 described later. By controlling the rotation speed of the motor, the amount of composition X supplied from the storage section 14 in which the composition X is stored to the nozzle 15 that discharges the composition X via the pump section 15P is controlled. A switch SW is attached between the auxiliary electric circuit 13 and the low-voltage power supply 11, and the electrostatic spinning apparatus 10 can be operated/stopped by turning the switch SW on and off.

The main body 10B further includes a power source 16 and a power transmission unit 17. The power source 17 in this embodiment generates power to eject the composition X contained in the storage unit 14 from the nozzle 15 via the pump unit 15P. The power source 16 in the present invention is provided with a motor or the like, receives power from the low-voltage power source 11, operates under the control of the auxiliary electric circuit 13, and generates power. The power generated by the power source 16 is configured to be supplied to the nozzle 15 from the storage unit 14 via the pump unit 15P by the power transmission unit 17, which transmits the power to the pump unit 15P.

The power transmission section 17 provided in the main body section 10B transmits the power generated from the power source 16, such as a motor, to the pump section 15P. This allows the composition X contained in the storage section 14 to be supplied to the nozzle 15 via the pump section 15P. There are no particular limitations on the method of transmitting the power from the power source 16 to the pump section 15P, but for example, a convex structure (not shown) can be formed on the tip of the power transmission section 17 made of a shaft, and the convex structure can be fitted into the power transmission recess 15b provided in the pump section 15P to transmit the rotational power of the motor in the power source 16 to the pump section 15P.

Because the composition X used in the present invention is conductive, the high voltage applied to the nozzle 15 may be applied to the power source 16 via the pump section 15P or the power transmission section 17, which may damage the electrostatic spinning device 10 or cause electric charge leakage and failure to spray. Therefore, from the viewpoint of ensuring insulation during use of the electrostatic spinning device 10 and preventing damage to the electrostatic spinning device 10, and from the viewpoint of preventing leakage of current via the composition X and ensuring stability of spinning, it is preferable that the power transmission section 17 electrically insulates the power source 16 from the cartridge section 10A. This effectively prevents the high voltage applied to the nozzle 15 from being unintentionally applied to the power source 16. As a method for electrically insulating the power source 16 from the cartridge section 10A, for example, a method of using a member made of a non-conductive material such as plastic or ceramic as the power transmission section 17 can be mentioned. As long as the power transmission section 17 electrically insulates the power source 16 from the cartridge section 10A, the other constituent materials may be conductive or non-conductive.

The above configuration allows precise control of the amount of composition X supplied from the storage section 14 to the nozzle 15, and the portability of the electrospinning device 10 can be further improved due to the miniaturization of the main body section 10B.

The manner of use of the electrospinning apparatus will be described with reference to FIG.
The electrospinning apparatus 10 having the configuration shown in the embodiment shown in Figures 1 to 6 can be used, for example, as shown in Figure 7. Figure 7 shows a handy type electrospinning apparatus 10 having a size that can be held with one hand. In the electrospinning apparatus 10 shown in the figure, all of the components shown in the configuration diagrams shown in Figures 1, 2, or 5 are housed in a cylindrical housing 20. Although the housing 20 shown in Figure 7 is cylindrical, the shape of the housing 20 is not particularly limited as long as it has a size that can be held with one hand and all of the components shown in Figure 1 are housed therein, and it may be a cylindrical shape such as an elliptical cylinder or a regular polygonal cylinder. The "size that can be held with one hand" means that the weight of the housing 20 in which the electrospinning apparatus 10 is housed is preferably 2 kg or less, the maximum length in the longitudinal direction of the housing 20 is preferably 40 cm or less, and the volume of the housing 20 is preferably 3000 cm ³ or less. A nozzle (not shown) is arranged at one end 10a in the longitudinal direction of the housing 20. The nozzle is arranged in the housing 20 so that the spray direction of the composition X coincides with the vertical direction of the housing 20 and is convex toward the skin. By arranging the nozzle tip so that it is convex toward the skin in the vertical direction of the housing 20, the composition X is less likely to adhere to the housing, and a coating can be stably formed.

[Formation of a film on the surface of the human body]
Next, the formation of a coating on the surface of the human body will be described.
When the electrospinning apparatus 10 is operated, a user, i.e., a person who forms a coating on a part of the human body surface where a coating is to be formed by electrospinning, holds the apparatus 10 by hand and directs one end 10a of the apparatus 10, where a nozzle (not shown) is located, to the application site where electrospinning is to be performed. FIG. 7 shows a state in which one end 10a of the electrospinning apparatus 10 is directed toward the inside of the forearm of the user. In this state, the switch of the apparatus 10 is turned on to perform electrospinning. When the power is turned on to the apparatus 10, an electric field is generated between the nozzle and the skin. In the embodiment shown in FIG. 7, a positive high voltage is applied to the nozzle, and the skin becomes the negative electrode. When an electric field is generated between the nozzle and the skin, the composition X at the tip of the nozzle is polarized by electrostatic induction, and the tip part becomes cone-shaped, and droplets of the charged composition X are ejected from the tip of the cone along the electric field into the air (atmosphere) toward the skin. When the solvent component (a) evaporates from the charged composition X discharged into space (air), the charge density on the surface of the composition X becomes excessive, and the composition X spreads into space while repeatedly being finely divided by Coulomb repulsion, and reaches the skin. In this case, by appropriately adjusting the viscosity of the composition X, the discharged composition can be made to reach the application site in the form of droplets. In addition, while being discharged into space, the volatile substance as the solvent is evaporated from the droplets, and the polymer having the film-forming ability as the solute is solidified, while being elongated and deformed by the potential difference to form fibers, and the fibers can be deposited on the application site. For example, by increasing the viscosity of the composition X, the composition can be easily deposited on the application site in the form of fibers. As a result, a porous coating, which is a fiber deposit, is formed on the surface of the application site. Such a porous coating, which is a fiber deposit, can also be formed by adjusting the distance between the nozzle and the skin or the voltage applied to the nozzle.

During electrospinning, a high potential difference occurs between the nozzle and the surface of the human body. However, because the impedance is very large, the current flowing through the human body is extremely small. For example, the inventors have confirmed that the current flowing through the human body during electrospinning is several orders of magnitude smaller than the current flowing through the human body due to static electricity generated in everyday life.

When a fiber deposit is formed by electrospinning, the thickness of the fiber, expressed as a circle equivalent diameter, is preferably 100 nm or more, more preferably 500 nm or more. Also, it is preferably 15,000 nm or less, more preferably 10,000 nm or less. The fiber thickness can be measured, for example, by observing the fiber at 10,000 times magnification using a scanning electron microscope (SEM), removing defects (fiber clumps, fiber intersections, and liquid droplets) from the two-dimensional image, arbitrarily selecting 10 fibers, drawing a line perpendicular to the longitudinal direction of the fiber, and directly reading the fiber diameter.

The coating, which is a fiber deposit formed by electrospinning, has moisture on the surface side of the constituent fibers. The surface side of the fiber means the surface, a part of the surface, or between the fibers. By changing the contents of components (b) and (c) in composition X, it is possible to improve the adhesion and transparency of the coating formed on the surface of the human body. In addition, the coating, which is a fiber deposit formed by electrospinning, may contain a component derived from composition X.

In the case of skin containing sweat and sebum, the fibers tend to swell or plasticize due to the water and oil being compounded in the fibers. For example, when the same composition is electrostatically spun for 5 seconds on a metal surface not containing water or oil and on a skin surface containing water and oil, such as the palm, to produce a thin film, the fiber electrostatically spun on the skin surface becomes larger in diameter over time due to swelling than the fiber electrostatically spun on the metal surface when the change in fiber diameter is observed over time. In this way, the fiber-containing coating formed by electrostatic spinning becomes softer due to plasticization by the oil and water in the skin, improving the ability of the fiber itself to follow the skin texture, and moisture bleeds out from the fiber and exists on the fiber surface or between the fibers, making the fiber-containing coating translucent or transparent, giving it a natural appearance. In the case of a coating-forming object containing sweat and sebum, the fiber diameter due to swelling satisfies the following formula (1).
(Fiber diameter after 30 seconds of spinning on skin) > (Fiber diameter after 30 seconds of spinning on metal plate) ... (1)

The contents of components (a), (b), (c) and (d) in composition X are measured as follows. Component (a), which is a volatile substance, is not present in the formed coating, or volatilizes even if present. Therefore, the measurement is performed in a state in which the formed coating contains only components (b), (c) and (d), and their contents are measured as follows.

<Method for measuring the contents of components (b), (c) and (d) in composition X>
There are methods for separation and identification in solution state using liquid chromatography (HPLC) and infrared spectroscopy (IR). With liquid chromatography, the components with larger molecular weights are eluted first, so it is possible to predict the molecular weight and identify the composition based on the elution position of the components. With IR analysis, it is also possible to assign and identify functional groups from individual absorbers, and generally identification is possible by comparing the IR chart of the component with the standard chart of commercially available additives.

<Method for measuring the contents of components (b), (c) and (d) in the formed coating>
A solvent capable of dissolving the coating is searched for, and after dissolving the coating in the solvent, it is separated and identified by liquid chromatography (HPLC) or by infrared spectroscopy (IR).

The fibers forming the coating are continuous fibers of infinite length in principle, but preferably have a length of at least 100 times the thickness of the fiber. In this specification, a fiber having a length of 100 times the thickness of the fiber is defined as a "continuous fiber". The coating produced by the electrospinning method is preferably a porous discontinuous coating that is a deposit of continuous fibers. A coating of this type is not only able to be handled as a single sheet as an assembly, but also has the advantage of being very soft, not easily falling apart even when shear force is applied to it, and having excellent followability to body movements. It also has the advantage that the coating can be easily removed completely. In contrast, a continuous coating that does not have pores is not easy to peel off, and has low sweat dissipation, so there is a risk of sweating on the skin, etc. In addition, a porous discontinuous coating made of an assembly of particles is difficult to completely remove without damaging the skin, etc., as it requires actions such as applying friction to the entire coating in order to completely remove the coating.

In the electrostatic spinning process using the electrostatic spinning device 10, the composition X that has been electrostatically spun into a fiber reaches the skin directly with the components (b), (c) and (d) charged while the component (a) evaporates. As described above, the skin is also charged, so the fibers adhere to the skin in the form of a single membrane due to electrostatic forces. Since the surface of the skin has fine irregularities such as texture, the fibers adhere to the surface of the skin in the form of a single membrane even more closely, coupled with the anchor effect of the irregularities. When electrostatic spinning is completed in this way, the power to the electrostatic spinning device 10 is turned off. This causes the electric field between the nozzle and the skin to disappear, and the charge is fixed on the surface of the skin. As a result, the adhesion of the coating in the form of a single membrane is further expressed, the coating is less likely to peel off from the edge during wear, and durability during use is improved. In addition, since the fibers that make up the coating contain moisture, the coating does not feel strange, and excellent moisturizing and softening effects are obtained, allowing the coating to adhere sufficiently to the skin. The reason for this is thought to be that the presence of moisture on the surface of the fibers or between the fibers softens the fibers themselves due to a plasticizing effect, improving their ability to conform to finely uneven surfaces, and moisture bleeds out onto the fiber surface, forming a liquid bridge between the fibers and the skin. Furthermore, since the coating has a moisture-bearing coating in which moisture is present between the fibers or on the surface of the fibers that make up the coating, the fibers that make up the coating are less likely to reflect light, and the coating tends to appear transparent, allowing the skin to be covered in a natural-looking state. These effects are further enhanced by the application of liquid agent Y, which will be described later.

The distance between the nozzle and the surface of the human body depends on the voltage applied to the nozzle, but in order to successfully form a coating, it is preferably 10 mm to 160 mm, more preferably 20 mm to 150 mm, and even more preferably 40 mm to 150 mm. The distance between the nozzle and the skin can be measured using a commonly used non-contact sensor, etc.

Regardless of whether the coating formed by electrospinning contains fibers or not, the basis weight of the coating is preferably 0.1 g/ ^m2 or more, more preferably 1 g/ ^m2 or more. Also, it is preferably 50 g/m2 ^or less, more preferably 40 g/ ^m2 or less. For example, the basis weight of the coating is preferably 0.1 g/ ^m2 or more and 50 g/ ^m2 or less, more preferably 1 g/ ^m2 or more and 40 g/m2 or ^less . By setting the basis weight of the coating in this way, the adhesion of the coating can be improved.

In the present invention, before or after the electrospinning step of forming a coating on the surface of the human body by electrospinning described above, a step of applying a liquid agent Y other than composition X, which contains one or more selected from a polyol that is liquid at 20°C and an oil that is liquid at 20°C, to the surface of the human body by a means other than electrospinning, for example, may be performed. By performing the step of applying liquid agent Y, the coating formed in the electrospinning step becomes more compatible with the application site, the coating can be highly adherent to the skin, and can also be made extremely transparent. For example, a step is less likely to occur between the end of the coating and the surface of the human body, thereby improving the adhesion between the coating and the surface of the human body. As a result, peeling or tearing of the coating is less likely to occur. In a more preferred embodiment, when the coating is a porous coating that is a deposit of fibers, the adhesion to the surface of the human body is high despite the high porosity, and a large capillary force is easily generated. Furthermore, when the fibers are fine, it is easy to increase the specific surface area of the porous coating.

In particular, by carrying out a liquid agent Y application process before or after forming a porous coating, which is a fiber deposit, in the electrostatic spinning process, a coating is formed in which the liquid agent Y is present between the fibers that form the porous coating and/or on the fiber surface. This improves the adhesion of the coating, and maintains or improves the transparency of the coating when viewed with the naked eye. In particular, when the coating is colorless and transparent or colored and transparent, the coating becomes more difficult to see, making it look like natural skin. Also, when the coating is colored and transparent, the coating appears transparent, making it look like part of the skin.

Examples of oils that are liquid at 20°C include linear or branched hydrocarbon oils such as liquid paraffin, light isoparaffin, liquid isoparaffin, squalane, and squalene; ester oils such as monoalcohol fatty acid esters, monoglycerin fatty acid esters, triglycerin fatty acid esters, and polyhydric alcohol fatty acid esters; silicone oils such as dimethylpolysiloxane, dimethylcyclopolysiloxane, methylphenylpolysiloxane, methylhydrogenpolysiloxane, and higher alcohol-modified organopolysiloxane; and higher alcohols. Among these, from the viewpoint of usability such as smoothness during application, one or more selected from hydrocarbon oils and ester oils are preferred. In addition, it is possible to contain vegetable oils such as olive oil and jojoba oil that contain multiple types of hydrocarbon oils and ester oils, and animal oils such as liquid lanolin, or one or more liquid oils selected from the above-mentioned oils that are liquid at 20°C can be used in combination.

Examples of the hydrocarbon oil include liquid paraffin, squalane, squalene, n-octane, n-heptane, cyclohexane, light isoparaffin, and liquid isoparaffin, and from the viewpoint of usability, one or more selected from liquid paraffin and squalane are preferred. From the viewpoint of adhering the electrostatically discharged coating to the skin, the viscosity of the hydrocarbon oil at 30° C. is preferably 10 mPa·s or more, more preferably 30 mPa·s or more. From this viewpoint, the total content of isododecane, isohexadecane, and hydrogenated polyisobutene, which have a viscosity of less than 10 mPa·s at 30° C., in the liquid agent Y is preferably 10% by mass or less, more preferably 5% by mass or less, even more preferably 1% by mass or less, and even more preferably 0.5% by mass or less, and may not be contained.
Similarly, from the viewpoint of allowing the electrostatically discharged coating to adhere to the skin, the viscosity of the ester oil and silicone oil at 30° C. is preferably 10 mPa·s or more, and more preferably 30 mPa·s or more. The viscosity here is measured at 30° C. using a BM type viscometer (manufactured by Tokimec Co., Ltd., measurement conditions: rotor No. 1, 60 rpm, 1 minute).

From the same viewpoint, the total content of ether oils such as cetyl-1,3-dimethylbutyl ether, dicapryl ether, dilauryl ether, and diisostearyl ether in liquid agent Y is preferably 10% by mass or less, more preferably 5% by mass or less, and even more preferably 1% by mass or less.

Examples of the ester oil include esters of linear or branched fatty acids and linear or branched alcohols or polyhydric alcohols. Specific examples include isopropyl myristate, cetyl octanoate, octyldodecyl myristate, isopropyl palmitate, butyl stearate, hexyl laurate, myristyl myristate, decyl oleate, hexyldecyl dimethyloctanoate, cetyl lactate, myristyl lactate, lanolin acetate, isocetyl stearate, isocetyl isostearate, cholesteryl 12-hydroxystearate, ethylene glycol di-2-ethylhexanoate, dipentaerythritol fatty acid esters, mono N-Alkyl glycol isostearate, neopentyl glycol dicaprate, diisostearyl malate, glycerin di-2-heptylundecanoate, trimethylolpropane tri-2-ethylhexanoate, trimethylolpropane triisostearate, pentaerythritol tetra-2-ethylhexanoate, glyceryl tri-2-ethylhexanoate, trimethylolpropane triisostearate, cetyl 2-ethylhexanoate, 2-ethylhexyl palmitate, diethyl naphthalene dicarboxylate hexyl, benzoate (carbon number 12-15) alkyl, cetearyl isononanoate, tri(caprylic/capric)glycerin, butylene glycol (dicaprylic/capric), glyceryl trilaurate, glyceryl trimyristate, glyceryl tripalmitate, glyceryl triisostearate, glyceryl tri-2-heptylundecanoate, glyceryl tribehenate, glyceryl tricocoate, methyl ester of castor oil fatty acids, oleyl oleate, 2-heptyl palmitate undecyl, diisobutyl adipate, N-lauroyl-L-glutamic acid-2-octyldodecyl ester, di-2-heptylundecyl adipate, ethyl laurate, di-2-ethylhexyl sebacate, 2-hexyldecyl myristate, 2-hexyldecyl palmitate, 2-hexyldecyl adipate, diisopropyl sebacate, di-2-ethylhexyl succinate, triethyl citrate, 2-ethylhexyl paramethoxycinnamate, tripropylene glycol dipivalate, etc.

Among these, from the viewpoint of adhering the electrostatically discharged coating to the skin and from the viewpoint of excellent sensation when applied to the skin, the following have been selected: octyldodecyl myristate, myristyl myristate, isocetyl stearate, isocetyl isostearate, cetearyl isononanoate, diisobutyl adipate, di-2-ethylhexyl sebacate, isopropyl myristate, isopropyl palmitate, diisostearyl malate, neopentyl glycol dicaprate, alkyl benzoate (carbon number 12-15), tri(capryl) At least one selected from isopropyl myristate, isopropyl palmitate, diisostearyl malate, neopentyl glycol dicaprate, alkyl benzoate (12-15 carbon atoms), and tri(caprylic acid/capric acid)glycerin is more preferred, and at least one selected from neopentyl glycol dicaprate, alkyl benzoate (12-15 carbon atoms), and tri(caprylic acid/capric acid)glycerin is even more preferred.

As the triglyceride, fatty acid triglycerides are preferred, and for example, those contained in natural oils such as olive oil, jojoba oil, macadamia nut oil, medfoam oil, castor oil, safflower oil, sunflower oil, avocado oil, canola oil, apricot kernel oil, rice germ oil, and rice bran oil may be contained as natural oils.

Examples of higher alcohols include liquid higher alcohols with 12 to 20 carbon atoms, such as isostearyl alcohol and oleyl alcohol.

Preservatives include phenoxyethanol, methyl parahydroxybenzoate, ethyl paraaminobenzoate, isobutyl parahydroxybenzoate, isopropyl parahydroxybenzoate, ethyl parahydroxybenzoate, butyl parahydroxybenzoate, propyl parahydroxybenzoate, benzyl parahydroxybenzoate, and ethylhexanediol.

Examples of silicone oils include dimethylpolysiloxane, dimethylcyclopolysiloxane, methylphenylpolysiloxane, methylhydrogenpolysiloxane, and higher alcohol-modified organopolysiloxane.
From the viewpoint of ensuring close adhesion of the electrostatically ejected coating to the skin, the kinetic viscosity of the silicone oil at 25°C is preferably 3 ^mm2 /s or more, more preferably 4 ^mm2 /s or more, even more preferably 5 ^mm2 /s or more, and is preferably 30 ^mm2 /s or less, more preferably 20 ^mm2 /s or less, and even more preferably 10 ^mm2 /s or less.
Among these, it is preferable to contain dimethylpolysiloxane from the viewpoint of adhering the electrostatically discharged coating to the skin.

The content of liquid oil in the liquid agent Y is preferably 0.1% by mass or more, more preferably 0.5% by mass or more, and even more preferably 5% by mass or more. It is also preferably 100% by mass or less. The content of liquid oil in the liquid agent Y is preferably 0.1% by mass or more and 100% by mass or less, and more preferably 0.5% by mass or more and 100% by mass or less.

The HLB value of the liquid oil is preferably 10 or less, more preferably 8 or less, and even more preferably 6 or less. The HLB value is an index showing the hydrophilic-lipophilic balance, and in the present invention, the value calculated by the following formula proposed by Oda and Teramura et al. is used.
HLB = (Σ inorganic value / Σ organic value) x 10

Examples of polyols that are liquid at 20°C and are used in liquid agent Y include alkylene glycols such as ethylene glycol, propylene glycol, 1,3-propanediol, and 1,3-butanediol; polyalkylene glycols such as diethylene glycol, dipropylene glycol, polyethylene glycols with a weight average molecular weight of 2000 or less, and polypropylene glycol; and glycerins such as glycerin, diglycerin, and triglycerin. Among these, from the viewpoint of usability such as smoothness during application, one or more selected from ethylene glycol, propylene glycol, 1,3-butanediol, dipropylene glycol, polyethylene glycols with a weight average molecular weight of 2000 or less, glycerin, and diglycerin are preferred, and one or more selected from propylene glycol, 1,3-butanediol, and glycerin are more preferred, and one or more selected from propylene glycol and 1,3-butanediol are even more preferred.

It is preferable that liquid Y has a viscosity of 5000 mPa·s or less at 25°C in order to improve adhesion between the coating formed by electrospinning and the application site. The method for measuring the viscosity of the liquid is as described above.

Various methods can be used to apply the liquid agent Y to the skin. For example, by applying the liquid agent Y to the skin by a method such as dripping or sprinkling, and providing a step of spreading the liquid agent Y, it becomes possible to blend the liquid agent Y with the skin or coating, and a thin layer of the liquid agent Y can be formed. The step of spreading the liquid agent Y can be, for example, a method such as rubbing with a tool such as the user's own finger or an applicator. The liquid agent Y may be simply dripped or sprinkled, but by providing a step of spreading the liquid agent Y, it becomes possible to blend the liquid agent Y with the skin or coating, and the adhesion of the coating can be sufficiently improved. Alternatively, the liquid agent Y can be ejected onto the skin to form a thin layer of the liquid agent Y. In this case, a separate spreading step is not particularly necessary, but the operation of spreading the liquid agent Y after ejection is not prevented. In addition, when applying liquid agent Y after forming the coating, a sufficient amount of liquid agent Y is applied to the skin, and excess liquid agent Y can be removed by a process of contacting the sheet material with the area where the liquid agent has been applied.

The amount of liquid agent Y applied to the skin should be a necessary and sufficient amount to improve the adhesion between the skin and the coating. When liquid agent Y contains liquid oil, in order to ensure the adhesion between the skin and the coating, the amount of liquid agent Y applied to the skin is such that the basis weight of the liquid oil is preferably 0.1 g/m ² or more, more preferably 0.2 g/m ² or more, and is preferably 40 g/m ² or less, and more preferably 35 g/m ² or less. For example, the amount of liquid agent Y applied to the skin is such that the basis weight of the liquid oil is preferably 0.1 g/m ² or more and 40 g/m ² or less, more preferably 0.2 g/m ² or more and 35 g/m ² or less.
The amount of Liquid Preparation Y applied to the skin or coating is preferably 5 g/ ^m2 or more, more preferably 10 g/ ^m2 or more, and even more preferably 15 g/m2 or more, and is preferably 50 g/ ^m2 or ^less , and more preferably 45 g/m2 ^{or less} , from the viewpoint of improving adhesion between the skin and the coating and improving transparency.

In the embodiment of the present invention described above, a person who wants to form a coating on his or her own skin holds the electrospinning device 10 and generates an electric field between the conductive nozzle of the device 10 and the person's skin. However, as long as an electric field is generated between the two, the person who wants to form a coating on his or her own skin does not need to hold the electrospinning device 10.

[Sheet for application to the surface of the human body]
The present invention further relates to the following components (B) and (d):
(B) Water-insoluble polymer
The present invention provides a sheet for application to the surface of the human body, which comprises fibers containing one or more water-soluble deodorizing components selected from (d) polyhydroxyamine, polyethyleneimine, alkanolamine, basic amino acid or a polymer thereof, and alkali metal phosphate, wherein the mass ratio (d)/(B) of component (d) to component (B) is 0.01 or more and 0.9 or less, the basis weight is 0.05 g/m2 or ^more and 50 g/m2 ^or less, and the equivalent circle diameter of the fibers is 100 nm or more and 15,000 nm or less.

The sheet for application to the human body surface of the present invention is formed by discharging the above-mentioned composition X from an electrostatic spinning device onto a location other than the human body surface, and depositing fibers containing components (B) and (d) in the form of a film. A flat substrate layer can be used for the location other than the human body surface to facilitate application to the human body surface. Examples of the flat substrate layer include chemical fiber cloth, and those with good releasability are preferred, such as synthetic resin films such as polyolefin, polyester, acrylic, rayon, and polyurethane, and natural cellulose fibers such as cotton, pulp, and paper.

The sheet for application to the human body surface of the present invention may be peeled off from the planar substrate layer after the volatile substances of the aforementioned component (a) have almost completely evaporated and the water of the component (c) has partially evaporated. The sheet can be peeled off and applied directly to the human body surface, or the sheet formed on the substrate layer can be pressed against the human body surface and applied to the human body surface, and used to deodorize malodors emitted from the human body surface.

The content of component (B) in the sheet for application to the human body surface is preferably 40% by mass or more, more preferably 50% by mass or more, and even more preferably 60% by mass or more. It is also preferably 98% by mass or less, more preferably 96% by mass or less, and even more preferably 95% by mass or less. The content of component (B) in the sheet for application to the human body surface is preferably 40% by mass or more and 98% by mass or less, more preferably 50% by mass or more and 96% by mass or less, and even more preferably 60% by mass or more and 95% by mass or less.

From the viewpoint of improving the deodorizing effect, the content of component (d) in the sheet for application to the human body surface is preferably 2% by mass or more, more preferably 3% by mass or more, even more preferably 4% by mass or more, and even more preferably 5% by mass or more. From the viewpoint of the stability of the sheet, it is preferably 40% by mass or less, more preferably 30% by mass or less, even more preferably 20% by mass or less, and even more preferably 15% by mass or less. The content of component (d) in the sheet for application to the human body surface is preferably 2% by mass or more and 40% by mass or less, more preferably 3% by mass or more and 30% by mass or less, even more preferably 4% by mass or more and 20% by mass or less, and even more preferably 5% by mass or more and 15% by mass or less.

The mass ratio (d)/(B) of component (d) to component (B) is 0.01 or more, preferably 0.02 or more, more preferably 0.04 or more, and even more preferably 0.1 or more, from the viewpoint of improving the deodorizing effect, and from the viewpoint of suppressing adhesion between the water-insoluble polymer fibers and maintaining a laminated state with a high surface area, it is 0.9 or less, preferably 0.8 or less, more preferably 0.7 or less, and even more preferably 0.6 or less. Note that the lower this ratio, the better the quality of the water-insoluble polymer fibers and the easier they are to laminate, but the deodorizing effect per sheet mass decreases. Therefore, when the mass ratio (d)/(B) is low, the basis weight can be increased to achieve both the quality of the water-insoluble polymer fibers and the deodorizing effect. In addition, the sheet for application to the human body surface of the present invention may contain a component derived from composition X in addition to the above components (B) and (d).

From the viewpoint of achieving both the quality of the water-insoluble polymer fiber and the deodorizing effect, the basis weight of the sheet for application to the human body surface is at least 0.05 g/ ^m2 , preferably at least 0.1 g/ ^m2 , ^more preferably at least 0.5 g/m2, even more preferably at ^least 1 g/m2, even more preferably at ^least 3 g/ ^m2 , and is at most 50 g/m2, preferably at ^most 40 g/m2, more preferably at most 30 g/ ^m2 , even more preferably at ^most 20 g/m2.

In the sheet for application to the human body surface, the equivalent circle diameter of the fibers containing components (B) and (d) is 100 nm or more and 15,000 nm or less, but is preferably 500 nm or more and 10,000 nm or less. The fiber thickness can be measured, for example, by observing the fibers at 10,000 times magnification using a scanning electron microscope (SEM), removing defects (fiber clumps, fiber intersections, and liquid droplets) from the two-dimensional image, arbitrarily selecting 10 fibers, drawing a line perpendicular to the longitudinal direction of the fibers, and directly reading the fiber diameter.

Examples 1 to 19, Comparative Examples 1 to 4
Composition X having the composition shown in Tables 1 to 3 was prepared, and a coating was formed using an electrostatic spinning device, and various evaluations were performed. Note that it was confirmed prior to the experiment that all of the water-soluble deodorant components used satisfied the above-mentioned conditions for water solubility.

Condition of Composition X Composition X prepared according to the recipe shown in Tables 1 to 3 was stirred at 60 rpm for 6 hours, allowed to stand overnight, and then visually observed for its condition and evaluated according to the following criteria.
×: Precipitation (cloudy precipitation, powdery precipitation) present ○: Transparent or almost uniformly dispersed

Coating Formation Method Composition X shown in Tables 1 to 3 was used to form a coating on a commercially available chemical fiber cloth as a skin model by electrospinning. Specifically, a plastic container 6.5 cm in diameter and 3.5 cm in height was covered with an 11 cm square piece of black chemical fiber cloth (40% by mass of acrylic fiber, 35% by mass of polyester, 22% by mass of rayon, 3% by mass of polyurethane), and a coating was formed from above by electrospinning under the following conditions.
The state of electrospinning was evaluated according to the following criteria.
×: Unable to spin (prescription solution cannot be discharged due to precipitation or sedimentation)
○: Can be spun (can be extruded and forms a film on the fabric)

<Electrostatic spinning conditions>
・Applied voltage: 10kV
・Distance between nozzle and skin model: 10cm
・ Discharge rate (flow rate) of composition X: 4 mL/h
Nozzle diameter: 0.8mm
Environment: 25℃, 40% RH

The thickness (circle equivalent diameter) of the fibers forming the coating was measured using the aforementioned scanning electron microscope (SEM) method, and was confirmed to be between 2000 nm and 10000 nm.

Method for measuring coating basis weight Each composition X shown in Tables 1 to 3 was prepared and a coating was formed on the black chemical fiber cloth on the cup under the same conditions, and used for mass calculation. After peeling off the coating with tweezers, it was dried at 70°C for 1 hour in an electric dryer and the mass was measured. The basis weight (g/ ^m2 ) was calculated from the mass and the area of the cup (area of a circle with a diameter of 6.5 cm). Using this method, it was confirmed that the basis weight of all coatings was approximately 5 g/ ^m2 .

Evaluation of film retention in a sweating model system In order to observe the film shape retention in a wet state with sweating, the film formed as described above was observed and evaluated in a sweating model system. Specifically, the cloth on which the film was formed was peeled off from the cup, and water was sprayed 20 times (total of 1.4 g) from the back side of the cloth to moisten it. After 20 minutes, the state of the film was observed to see if the film shape was maintained (whether it had dissolved).
×: The coating dissolves (a sticky feeling characteristic of polymers occurs)
○: The coating is not dissolved.

A cotton ball with a drop of malodor (5 μL of 1% by weight propylene glycol isovalerate solution) was placed inside the deodorization evaluation cup, and the cloth on which the coating was formed was placed over the cup again and secured with a rubber band. After 20 minutes, the odor emanating from the cloth was displayed according to the following 6-level odor intensity rating, and an overall rating of ◎, ○, △, or × was given. When there was no coating, the odor intensity was rated 3.

<Six-level odor intensity display>
0: Odorless 1: Barely detectable odor (detection threshold)
2: Weak odor that can be identified (cognitive threshold)
3: Easily detectable odor 4: Strong odor 5: Overpowering odor

◎: Very good deodorizing effect (isovaleric acid odor is 0 or 1)
○: Good deodorizing effect (odor of isovaleric acid is 2)
△: Deodorizing effect is somewhat good (smell of isovaleric acid is 2.5)
×: No deodorizing effect (smell of isovaleric acid is 3 or more)

Example 20
Using composition X of Example 10, a coating was formed on a commercially available chemical fiber fabric by electrostatic spinning under the same conditions as above.
A 40 mg coating was formed per piece (basis weight 10 g/m2) on a 20 ^cm2 area of the same chemical fiber cloth (40% by mass of acrylic fiber, 35% by mass of polyester, 22% by mass of rayon, ³ % by mass of polyurethane). The coating was peeled off from the chemical fiber cloth and attached to the depilated armpit.
After exercise during the day, the condition of the coating was maintained and a deodorizing effect on the armpits was also observed.

Example 21
Composition X of Example 4 was sprayed evenly directly onto half of the toe using an electrostatic spinning device (for about 30 seconds, application amount about 20 mg).
After exercise during the day, the condition of the coating was maintained and a deodorizing effect on the soles of the feet was also observed.

10. Electrostatic spinning device
11 Low voltage power supply
12 High voltage power supply
13 Auxiliary Electrical Circuits
14 Containers
15 Nozzles
15A Micro Gear Pump
15B Pipeline
15C Flexible Pipe
19 Current limiting resistor
20. Cabinet

Claims (13)

Composition X used to produce a fiber deposit upon discharge from an electrospinning apparatus, comprising:
Contains the following components (a) to (e) :
The content of component (b) is 4% by mass or more and 12% by mass or less,
The content of component (d) is 0.3% by mass or more and 5% by mass or less,
The content of component (e) is 1% by mass or more and 5% by mass or less,
The mass ratio (d)/(b) of the component (d) to the component (b) is 0.01 or more and 0.9 or less;
Composition X.
(a) one or more volatile substances selected from alcohols and ketones; and (b) a polyvinyl butyral resin .
(c) water; and (d) one or more water-soluble deodorizing components selected from polyhydroxyamines, polyethyleneimines, alkanolamines, basic amino acids or their polymers, and alkali metal phosphates.
(e) Polypropylene glycol Composition X according to claim 1, in which the content of component (c) is 6% by mass or more and 24% by mass or less. Composition X according to claim 1 or 2, in which the mass ratio (b)/(c) is 0.22 or more and 3 or less. Composition X according to any one of claims 1 to 3, in which the mass ratio (a)/(c) is 3 or more and 10 or less. Composition X according to any one of claims 1 to 4, in which the mass ratio (d)/(c) is 0.02 or more and 1 or less. Contains the following components (a) to (e) :
The content of component (b) is 4% by mass or more and 12% by mass or less,
The content of component (d) is 0.3% by mass or more and 5% by mass or less,
The content of component (e) is 1% by mass or more and 5% by mass or less,
The mass ratio (d)/(b) of the component (d) to the component (b) is 0.01 or more and 0.9 or less.
A method for forming a fiber-containing coating on a human body surface by electrostatically spinning composition X onto the human body surface .
(a) one or more volatile substances selected from alcohols and ketones; and (b) a polyvinyl butyral resin .
(c) water; and (d) one or more water-soluble deodorizing components selected from polyhydroxyamines, polyethyleneimines, alkanolamines, basic amino acids or their polymers, and alkali metal phosphates.
(e) Polypropylene glycol The coating forming method according to claim 6, wherein the human body surface is selected from the group consisting of skin, mucous membranes, and wounds. The coating formation method according to claim 6, wherein the surface of the human body is the skin of the armpits, lower legs, or buttocks. The method for forming a coating according to any one of claims 6 to 8, wherein the content of component (c) in composition X is 6% by mass or more and 24% by mass or less. The method for forming a coating according to any one of claims 6 to 9, wherein the mass ratio (b)/(c) in composition X is 0.22 or more and 3 or less. The method for forming a coating according to any one of claims 6 to 10, wherein the mass ratio (a)/(c) in composition X is 3 or more and 10 or less. The method for forming a coating according to any one of claims 6 to 11, wherein the mass ratio (d)/(c) in composition X is 0.02 or more and 1 or less. The following components (B) , (d) and (e):
(B) Polyvinyl butyral resin
(d) one or more water-soluble deodorizing components selected from polyhydroxyamines, polyethyleneimines, alkanolamines, basic amino acids or their polymers, and alkali metal phosphates;
(e) Polypropylene glycol
A sheet comprising fibers containing
The content of component (B) is 40% by mass or more and 98% by mass or less,
the mass ratio (d)/(B) of the component (d) to the component (B) is 0.01 or more and 0.9 or less;
The basis weight is 0.05 g/m2 or ^more and 50 g/m2 ^or less,
The equivalent circle diameter of the fiber is 100 nm or more and 15000 nm or less.
A sheet for application to the surface of the human body.

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