JP7074475B2 - Dosing mechanism - Google Patents

Description

Cross-reference of related applications

This application claims priority based on Japanese Patent Application No. 2015-128966 and is incorporated herein by reference.

The present invention relates to a dosing mechanism for administering a liquid drug filled in a drug container to a patient.

As a dosing mechanism for administering a liquid drug (drug solution) filled in a drug container to a patient, for example, there is an infusion pump device described in Patent Document 1. This infusion pump device is configured so that the pump unit can be attached to and detached from the main body (“power supply unit” in Patent Document 1) that drives the pump.

The pump unit described in Patent Document 1 is attached so as to be fitted into the main body. However, the pump unit may come off from the main body due to an impact or vibration from the outside, such as when something collides with the dosing mechanism. In that case, the medication could be interrupted.

Japanese Patent Application Laid-Open No. 2005-168958

Therefore, it is an object of the present invention to provide a dosing mechanism capable of reliably arranging the pump unit in the main body.

The present invention is a dosing mechanism for administering a liquid drug filled in a drug container to a patient, the one-side unit and the other-side unit superposed on the one-side unit when the dosing mechanism is used. The pump unit is provided with a main body having a main body and a pump unit that can be attached to and detached from the main body, and the pump unit is provided with a pump that sucks a drug from the drug container and discharges the drug to the patient. It is a dosing mechanism characterized in that it is held between one side unit and the other side unit.

Then, the pump unit can be held by pressure welding between the one-side unit and the other-side unit in a state of being mounted on the main body.

Then, the pump unit is held by pressure welding between the one-side unit and the other-side unit in a state of being mounted on the main body, so that conduction of driving power between the pump and the main body is ensured. be able to.

The pump unit includes a plurality of electrical contacts electrically connected to the main body, and the plurality of electrical contacts are used to confirm the contact to which drive power is supplied to the pump, the contact for grounding, and the continuity. Can include contacts.

It is a schematic diagram which shows the administration route of one Embodiment in this invention. The main body and the pump unit of the dosing mechanism of this embodiment are shown, and it is a schematic plan view of the state where the lid unit is opened with respect to the base unit. The main body and the pump unit of the dosing mechanism of this embodiment are shown, and it is a schematic vertical sectional view in a state where the lid unit is opened with respect to the base unit. The main body and the pump unit of the dosing mechanism of this embodiment are shown, and it is a schematic vertical sectional view in a state where the lid unit is closed with respect to the base unit. It is a front view which shows the base unit and the pump unit in the main body of the dosing mechanism of this embodiment. It is a right side view which shows the base unit and the pump unit in the main body of the dosing mechanism of this embodiment. FIG. 3 is a vertical cross-sectional view taken along the line AA of FIG. 3A showing a base unit and a pump unit in the main body of the dosing mechanism of the present embodiment. It is a rear view which shows the base unit and the pump unit in the main body of the dosing mechanism of this embodiment. It is a schematic diagram which shows the electric connection between the main body of the dosing mechanism of this embodiment, and a pump unit. The main body and the pump unit of another embodiment in this invention are shown, and it is the schematic of the vertical sectional view in the state which the lid unit is opened with respect to the base unit. The main body and the pump unit of another embodiment in this invention are shown, and it is the schematic of the vertical sectional view in the state which the lid unit is closed with respect to the base unit. The pump unit of another embodiment in this invention and the main body to which this pump unit is attached are shown. The pump unit of another embodiment in this invention and the main body to which this pump unit is attached are shown. The pump unit of another embodiment in this invention and the main body to which this pump unit is attached are shown. The pump unit of another embodiment in this invention and the main body to which this pump unit is attached are shown.

Next, the present invention will be described by taking up one embodiment. The dosing mechanism 1 of the present embodiment includes a main body 2 and a pump unit 3 that can be attached to and detached from the main body 2. As shown in FIG. 1, the dosing mechanism 1 is attached in the middle of the dosing route F from the drug container F1 such as an infusion bag to the patient P.

As shown in FIGS. 2A to 2C, the main body 2 is a part for holding the pump unit 3 and performing various detections, controls, and managements. As shown in FIG. 1, the drug container side tube F2 and the patient side tube F5 are connected to the pump unit 3 held by the main body 2. Since the main body 2 and the pump unit 3 are schematically shown in FIGS. 2A to 2C, the morphology shown in FIGS. 2A to 2C may not match the morphology shown in FIGS. 3A to 3D. ..

As shown in FIGS. 2A to 2C, the main body 2 includes a base unit 211 as a one-side unit and a lid unit 212 as the other-side unit. The base unit 211 is a part that detects by a sensor and controls the pump unit 3. The lid unit 212 is a portion where the user operates and various information is displayed. Therefore, although not shown, an operation button and a display unit are provided on the outer surface of the lid unit 212. Various display means such as a liquid crystal panel can be used for the display unit. Further, by using a touch panel, the operation buttons and the display unit can be integrated.

In this embodiment, the pump unit 3 is fitted into the base unit 211. The base unit 211 and the lid unit 212 have a hollow box shape, and the plan view is substantially rectangular. The base unit 211 and the lid unit 212 are rotatably connected to each other via hinges 213 and 213 provided so as to connect one side of both units 211 and 212 in a plan view. The open state of both units 211 and 212 is shown in FIGS. 2A and 2B, and the closed state is shown in FIG. 2C. When the dosing mechanism 1 is used, the base unit 211 and the lid unit 212 are overlapped and closed with the pump unit 3 fitted in the base unit 211. In this closed state, the inner surface 2111 of the base unit 211 and the inner surface 2121 of the lid unit 212 face each other and come into contact with each other. Each inner surface 211, 2121 is a flat surface in this embodiment. In order to maintain the closed state of both units 211 and 212, a lock portion 214 which can fix both units 211 and 212 in the closed state is provided on the side opposite to the side where the hinge 213 is provided.

The inner surface 2121 of the lid unit 212 comes into contact with the side surfaces of the suction side tube 33 and the discharge side tube 34 of the pump unit 3 when the base unit 211 and the lid unit 212 are closed. Further, a rubber pressing pad 2122 is attached to the inner surface 2121 of the lid unit 212. The pressing pad 2122 comes into contact with the case 37 of the pump unit 3 when the base unit 211 and the lid unit 212 are closed. By this contact, the case 37 is pushed toward the bottom surface side of the pump unit arrangement recess 22 formed in the base unit 211. Therefore, the conduction between the main body side electric contacts 27M, 27C, 27G shown in FIG. 4 and the pump unit side electric contacts 38M, 38C, 38G is ensured.

As shown in FIGS. 3A to 3D, the base unit 211 of the main body 2 includes a pump unit placement recess 22 which is a recess into which the pump unit 3 is fitted. The upper side shown in FIGS. 3A to 3D is the drug container F1 side (suction side) when the medication mechanism 1 is used, and the lower side is the patient P side (discharge side) when the medication mechanism 1 is used. In this embodiment, the pump unit placement recess 22 is provided only in the base unit 211. However, the present invention is not limited to this, and as shown in FIGS. 5A and 5B, the pump unit arrangement recess 22 may be provided in both the base unit 211 and the lid unit 212.

As shown in FIG. 4, a plurality of main body side electric contacts 27M, 27C, 27G are provided on the bottom surface of the pump unit arrangement recess 22. A plurality of electric contacts 27M, 27C, 27G on the main body side are provided corresponding to the electric contacts 38M, 38C, 38G on the pump unit side. In this embodiment, three are provided. However, the number may be four or more.

When the pump unit 3 is fitted in the pump unit arrangement recess 22, the electric contacts 27M, 27C, 27G on the main body side and the electric contacts 38M, 38C, 38G on the pump unit side are electrically connected to each other. As a result, the driving power for driving the pump 31 can be supplied from the main body side electric contacts 27M, 27C, 27G to the pump unit 3. Further, by being connected to the grounding portion G, the pump unit 3 is grounded, and the continuity of the pump 31 can be confirmed as described later.

Above and below the pump unit placement recess 22 in FIGS. 3A to 3D, tube placement grooves 23 for arranging the suction side tube 33 and the discharge side tube 34 of the pump unit 3 are formed.

The base unit 211 of the main body 2 is provided with a sensor that can detect the liquid feeding status of the pump unit 3. As this sensor, in the present embodiment, a pressure sensor 24 and a bubble sensor 25 are provided. The pressure sensors 24 are provided at two locations on the main body 2, the drug container F1 side and the patient P side. However, it may be provided only at one place on the drug container F1 side or the patient P side.

Each pressure sensor 24 is provided at a position corresponding to the suction side tube 33 and the discharge side tube 34 in the pump unit 3 attached to the main body 2. This pressure sensor 24 utilizes a phenomenon that when the pressure in the tube rises, the tube expands to expand the diameter of the tube, and when the pressure in the tube decreases, the tube contracts to shrink the diameter of the tube. However, the pressure change in each of the tubes 33 and 34 is detected by the diameter and dimensional change of the suction side tube 33 and the discharge side tube 34.

Specifically, as shown in FIGS. 3A and 3C, each pressure sensor 24 is provided with a movable block 241 having a groove into which the tubes 33 and 34 are fitted so as to be movable between the front side and the back side. .. On the back surface side of the movable block 241 is an element 242 capable of outputting a voltage by referring to the received load, which is arranged in contact with the movable block 241. The tubes 33 and 34 are restricted from moving to the front side by the inner surface 2121 of the lid unit 212 of the main body 2. Therefore, the movable block 241 moves according to the expansion / contraction of the tubes 33, 34, and the voltage output from the element 242 changes according to the load applied to the element 242, so that the inside of each tube 33, 34 is changed. Pressure change can be detected.

When the tubes 33 and 34 expand, they come into contact with the inner surface 2121 of the lid unit 212. Therefore, since the tubes 33 and 34 do not shift to the front side with respect to each pressure sensor 24 after the contact, the pressure change in each pressure sensor 24 is accurately detected.

If a blockage occurs in the middle section of the medication path F due to bending of the tube or the like, the pump is in a state where the drug solution is difficult to flow from the drug container F1 side in the blockage on the upstream side of the pump 31 in the pump unit 3. Since 31 performs suction, the suction side tube 33 contracts due to a negative pressure inside due to the continuation of driving of the pump 31. On the other hand, in the case of obstruction on the downstream side of the pump 31, the pump 31 discharges the drug solution in a state where it is difficult for the drug solution to flow to the patient P side. do. Therefore, the occurrence of blockage can be grasped by the detection of the pressure sensor 24. As shown in FIG. 1, the pump unit 3 is provided with a bypass pipe 35 and a bypass on-off valve 36 as a relief flow path for releasing excess chemicals generated at the time of closure so that inconvenience does not occur after the blockage is released. You may.

In addition to these, the base unit 211 of the main body 2 includes, for example, a control unit 261 that controls the pump of the pump unit 3 and processes and stores the detection results of each sensor, an internal power supply unit 262 that arranges batteries, and an external power input jack. 263, Flow rate jack 264 for inputting the detection value of the flow rate sensor for detecting the amount of drop, etc., attached to a drip tube (not shown) located on the patient P side of the drug container F1, output of medication history data and sensor detection results A communication jack 265 for performing the above may be provided. Further, although not shown, the lid unit 212 of the main body 2 has a speaker for emitting an alarm sound or the like, an LED lamp for displaying an alarm, and a sensor for detecting that the lid unit 212 has been opened. It may be provided with the liquid crystal display unit which displays the information of. Further, the main body 2 may be provided with a portion for attaching a band or the like for attaching the main body 2 to the body of the patient P, and a portion for attaching to a drip stand or the like used in a medical institution.

As shown in FIG. 1, the pump unit 3 includes a pump 31, a free flow prevention valve 32, a suction side tube (suction side pipe) 33, a discharge side tube (discharge side pipe) 34, and the like. The pump 31 and the free flow prevention valve 32 are housed in a case 37 (see FIGS. 3A and 3C) and integrated. Therefore, the pump unit 3 can be easily attached to and detached from the main body 2. The tips of the suction side tube 33 and the discharge side tube 34 are provided with connectors 331 and 341 that can be connected to the tubes F2 and F5 extending from the drug container F1 or the patient P.

As shown in FIG. 4, on the back surface of the case 37, electric contacts 38M, 38C, 38G on the pump unit side that can be electrically connected to the electric contacts 27M, 27C, 27G on the main body side are formed. Therefore, the back surface of the case 37 is aligned with the bottom surface of the pump unit placement recess 22 of the main body 2, and the electric contacts 27M, 27C, 27G on the main body side and the electric contacts 38M, 38C, 38G on the pump unit side are electrically connected. , The pump 31 can be energized so that it can be driven.

The pump 31 can suck the liquid drug (drug solution) from the drug container F1 and discharge it to the patient P. Examples of the pump method include a piston pump, a roller pump, and a diaphragm type pump, but a diaphragm type pump that does not require a motor is preferable. Therefore, in this embodiment, a diaphragm type pump is used. By adopting a diaphragm type pump as the pump 31, a motor is not required, so that the pump can be miniaturized. Therefore, the pump unit 3 can also be miniaturized, so that the dosing mechanism 1 can be made lighter. Therefore, the burden on the patient P when carrying the dosing mechanism 1 is reduced, which is particularly advantageous for the patient P who needs to constantly administer the drug solution. In addition, the diaphragm type pump can control the amount of chemicals discharged with high accuracy. The pump 31 of the present embodiment is a pump using the MEMS technique related to the integrated device, and is, for example, a micropump provided with a piezoelectric element (piezo element) described in Japanese Patent Application Laid-Open No. 2013-1172111. Used.

The free flow prevention valve 32 is provided to prevent an unintended flow through the pump 31 from being generated by the pressure of the chemical solution generated by gravity when the pump 31 is not driven.

The suction side tube 33 is a tube extending from the pump 31 to the drug container F1 side. The discharge side tube 34 is a tube extending from the pump 31 to the patient P side. These tubes 33 and 34 are made of a soft resin such as silicon rubber. Since changes in the diameters of the tubes 33 and 34 are detected by the pressure sensor 24 of the main body 2, the material (formulation of resin, density, etc.), tube thickness, and tube diameter are determined in advance at least in the portion arranged in the pressure sensor 24. It must be formed within the specified error range. In addition, unlike the present embodiment, when the pressure change is not detected by using the pipe, a hard pipe can be used instead of the soft tube for the pump unit 3.

The suction side tube 33 and the discharge side tube 34 of the present embodiment are arranged substantially in a straight line so as to pass through the case 37 as shown in FIGS. 2A and 3A. However, the present invention is not limited to this, for example, both tubes 33, 34 extend from the case 37 upward in the drawing as shown in FIG. 6A, and both tubes 33, 34 extend from the case 37 to the left in the drawing as shown in FIG. 6B. As shown in FIG. 6C, the suction side tube 33 extends upward in the drawing from the case 37, the discharge side tube 34 extends from the case 37 to the left in the drawing, and both tubes 33 and 34 are shown in the case 37 as shown in FIG. 6D. It can be provided in various forms with respect to the case 37, such as a form extending downward.

Connectors 331 and 341 are provided at the tips of the tubes 33 and 34. The connectors 331 and 341 are general-purpose products made of hard resin, and can be connected to the drug container side tube F2 and the patient side tube F5 (each connected to the connectors 331 and 341 of the pump unit 3, respectively, as shown in FIG. 1 by screwing. It is connected to connectors F3 and F4 having a shape that is in a "male" and "female" relationship. Since the pump unit 3 and the drug container side tube F2 can be separated and the pump unit 3 and the patient side tube F5 can be separated by the connectors 331 and 341, the distance between the drug container F1 and the patient P with respect to the dosing mechanism 1 can be freely set. Can be set to. Therefore, the tubes F2 and F5 are less likely to get in the way when the patient P carries the dosing mechanism 1.

The pump unit 3 of this embodiment can be disposable. Therefore, the dosing mechanism 1 can be used hygienically and safely. Although it depends on the type of the drug and the usage situation, the pump unit 3 is usually replaced in about 3 days, and in the long case, in about 30 days. Disposable pump unit 3 eliminates the need for a discharge accuracy test performed by a clinical engineer (ME) at a medical institution. Therefore, it becomes easy to manage the dosing mechanism 1 in the medical institution, and in the future, there is a possibility that the dosing mechanism 1 can be managed by a nurse or the like in each ward without the need for the hands of a clinical engineer.

Next, a method of using this dosing mechanism 1 will be briefly described. First, the tube F2 extending from the drug container F1 and the tube F5 extending from the patient P side (attached to the tube F5 if the needle F6 is not provided) are connected to the pump unit 3. Then, the pump unit 3 in a state where the tube F2 and the tube F5 are connected is attached to the main body 2 to be in the state shown in FIG. If necessary, install a drip tube or flow sensor. Next, the air bubbles in the route of administration F are removed. Then, the needle F6 is pierced into the patient P. Next, the driving of the pump 31 is started. As a result, the drug solution is sent into the body of patient P by the pump 31.

In the present embodiment, the pump unit 3 is provided between the base unit 211 as one side unit and the lid unit 212 as the other side unit in a state of being mounted on the main body 2. With this configuration, the pump unit 3 can be supported by the base unit 211 and the lid unit 212. Therefore, it is possible to prevent the pump unit 3 from coming off the main body 2.

More specifically, the pump unit 3 is sandwiched between the base unit 211 and the lid unit 212 and pressure-welded in a state of being mounted on the main body 2. By configuring the pump unit 3 so as to be held between the base unit 211 and the lid unit 212 by pressure welding in this way, it is possible to reliably suppress the pump unit 3 from coming off from the main body 2.

Further, the pump unit 3 is pressed against the base unit 211 in the main body 2 by the holding by the pressure welding. By this pressing, the electric contacts 27M, 27C, 27G on the main body side and the electric contacts 38M, 38C, 38G on the pump unit side are surely in contact with each other. Incidentally, in the present embodiment, since the pressing pad 2122 is attached to the inner surface 2121 of the lid unit 212, the pressing can be strengthened by the thickness of the pressing pad 2122. In this way, the conduction of the driving power to the main body 2 of the pump unit 3 is ensured. Therefore, as long as the base unit 211 and the lid unit 212 are not opened, the conduction of the driving power to the pump 31 is ensured, so that stable conduction is possible.

Further, the plurality of electric contacts included in the pump unit 3 include a contact 38M to which drive power is supplied to the pump 31, a grounding contact 38G, and a contact 38C for confirming the continuity of the pump 31.

The continuity confirmation contact 38C is provided so as to be connected to the ground wire as shown in FIG. Specifically, the electrical wiring branched from the electrical wiring from the pump 31 to the ground contact 38G is connected to the continuity confirmation contact 38C. Further, the continuity confirmation contact 27C on the main body 2 side is connected to the control unit 261 and the electrical wiring connected to the grounding contact 27G on the main body 2 side is branched and connected to the control unit 261. As a result, the monitoring current generated from the control unit 261 can be returned to the control unit 261 through the pump unit 3.

When the lid unit 212 is separated from the base unit 211, the continuity confirmation contacts 38C and 27C are separated, and the monitoring current does not flow, resulting in a non-conducting state. When the control unit 261 detects this non-conducting state, an alarm display is displayed on the main body 2 or an alarm sound is emitted from the main body 2, so that the user or the like can correct the lid unit 212. Can call attention to.

Here, since the pump 31 of the present embodiment is a micropump provided with a piezoelectric element (piezo element), the drive power is supplied to the pump 31 intermittently (repeated on / off) according to the drive frequency. In this way, the drive power may not flow, so even if an attempt is made to directly monitor the drive power, constant monitoring is impossible. Further, when the chemical discharge amount is set to be small, the drive frequency becomes small, so that the monitoring interval is extended when the drive power is directly monitored. Further, since the drive of the pump 31 is affected, it is not possible to constantly flow a monitoring current from the control unit to the pump 31.

On the other hand, by providing a contact dedicated to the continuity check of the pump 31 like the continuity check contacts 38C and 27C of the present embodiment, the continuity can be checked separately from the supply of the drive power to the pump 31. Therefore, continuous monitoring is possible. Further, the continuity of the pump 31 can be confirmed even before the driving, such as immediately after the pump unit 3 is mounted on the main body 2, even when the driving power is not supplied to the pump 31. As described above, there is a great merit of providing a contact dedicated to checking the continuity of the pump 31.

Although the embodiments of the present invention have been described above, the present invention is not limited to the above-described embodiments, and various modifications can be made without departing from the gist of the present invention.

Finally, the configuration and operation of the embodiment (including the modified form) will be summarized. The embodiment is a dosing mechanism 1 for administering a liquid drug filled in a drug container F1 to a patient P, and the one-side unit (base unit) 211 and the one-side unit (base unit) 211. On the other hand, a main body 2 having a other side unit (lid unit) 212 that is overlapped when the dosing mechanism 1 is used, and a pump unit 3 that can be attached to and detached from the main body 2 are provided, and the pump unit 3 delivers a drug. A pump 31 that sucks from the drug container F1 and discharges it to the patient P is provided, and the one-side unit (base unit) 211 and the other-side unit (lid unit) 212 are attached to the main body 2. It is a dosing mechanism 1 held in between.

According to this configuration, the pump unit 3 can be supported by the one-side unit (base unit) 211 and the other-side unit (cover unit) 212. Therefore, it is possible to prevent the pump unit 3 from coming off the main body 2.

Then, the pump unit 3 can be held by pressure welding between the one-side unit (base unit) 211 and the other-side unit (cover unit) 212 in a state of being mounted on the main body 2.

According to this configuration, the pump unit 3 can be reliably suppressed from coming off by holding the pump unit 3 by pressure contact between the one-side unit (base unit) 211 and the other-side unit (cover unit) 212.

The pump unit 3 is held by pressure welding between the one-side unit (base unit) 211 and the other-side unit (cover unit) 212 in a state of being mounted on the main body 2, thereby causing the pump. The continuity of the driving power between the 31 and the main body 2 can be ensured.

According to this configuration, unless the one-side unit (base unit) 211 and the other-side unit (cover unit) 212 are opened, the continuity of the driving power between the pump 31 and the main body 2 is ensured. Therefore, stable conduction is possible.

The pump unit 3 includes a plurality of electric contacts connected to the main body 2, and the plurality of electric contacts confirm the contact 38M to which the driving power is supplied to the pump 31, the grounding contact 38G, and the continuity. Contact 38C can be included.

According to this configuration, by providing the contacts 38M, 38G, 38C for confirming the continuity of the pump 31, it is possible to confirm the continuity separately from the supply of the driving power to the pump 31.

As described above, according to the above embodiment, it is possible to prevent the pump unit 3 from coming off the main body 2. Therefore, the pump unit 3 can be reliably arranged in the main body 2.

1 Dosing mechanism 2 Main body 211 One side unit, base unit 212 The other side unit, lid unit 3 Pump unit 31 Pump 38M Electric contact of pump unit (contact to which drive power is supplied)
38G pump unit electrical contacts (grounding contacts)
38C pump unit electrical contacts (contacts for checking continuity)
F1 drug container P patient

Claims (1)

A dosing mechanism for administering a liquid drug filled in a drug container to a patient.
A main body having a one-side unit and a other-side unit superposed on the one-side unit, and a pump unit that can be attached to and detached from the main body and sucks a drug from the drug container and discharges the drug to a patient. Equipped with
The one-side unit has a control unit for controlling the pump unit.
The other side unit has an operation unit for operating the pump unit.
The one-sided unit has a recess for accommodating the pump unit.
The other side unit is superposed on the one side unit so as to close the opening side of the recess while the pump unit is stored in the recess.
When the other side unit is overlapped with respect to the one side unit so as to be closed, the pump unit is stored in the recess and is pressed between the one side unit and the other side unit. Retained,
When the other side unit is overlapped with respect to the one side unit so as to be closed, the pump unit is stored in the recess by pressure contact between the one side unit and the other side unit. A dosing mechanism that ensures continuity of driving power between the pump unit and the main body by being held .

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