JP6676686B2 - Medical liquid circuit kit and liquid circuit system using the same - Google Patents

Description

  The present invention relates to a liquid circuit kit and a system for injecting a drug solution such as a contrast medium or a physiological saline solution into a patient, and particularly to a liquid circuit kit and a system that can be suitably used for angiography such as cardiac catheterization. About.

Examples of medical image diagnostic apparatuses include a CT (Computed Tomography) scanner and an MRI (Magnetic).
Resonance Imaging, PET (Position Emission Tomography), Angiography, and MRA (MR)
Angio) device. When capturing an image of a patient using these devices, a medical solution such as a contrast medium or physiological saline is often injected into the patient.

  Patent Literature 1 discloses a liquid circuit system used when performing angiography (for example, FIGS. 7A to 7B). This system draws a saline solution or a contrast medium source connected to a liquid circuit into a syringe and injects them into a patient.

JP 2007-222656 A

  In general, when performing angiography, it is necessary to perform suction of a contrast agent into a syringe and injection into a patient, and suction of saline into a syringe and injection into a patient in a predetermined order. (Details are described later). In such angiography, when the operator needs to operate the three-way stopcock of the liquid circuit, if the operator makes an operation error, the angiography will not be performed properly.

  The present invention has been made in view of such a problem, and an object of the present invention is to provide a liquid circuit kit and a liquid circuit system that can perform angiography well without requiring a complicated operation by an operator. To provide.

A liquid circuit kit according to one embodiment of the present invention for achieving the above object is as follows:
A medical liquid circuit kit used for angiography,
A contrast agent line connected to the contrast agent chamber;
A saline line connected to the saline chamber;
A syringe line connected to the syringe,
A patient line for delivering a contrast or saline solution to the patient,
A baseline portion to which each line is connected, wherein the contrast agent line and the physiological saline line are each connected in a T-shape,
And,
A first valve member disposed at a connection portion between the contrast agent line and the baseline portion, wherein (i) when a liquid is drawn toward an upstream side of the baseline portion, the contrast agent Flows from the line into the baseline portion, and (ii) when the liquid is pushed from the upstream side to the downstream side of the baseline portion, the liquid flows through the valve member in that direction. A first valve member configured to:
A second valve member disposed at a connection portion between the saline line and the baseline portion, wherein a liquid is pushed from an upstream side to a downstream side of the baseline portion or the saline A second valve member configured to flow liquid in that direction when pushed from the water line side toward the second valve member side;
A first release valve having a movable member and disposed on the saline line, wherein the release valve opens and closes the saline line by moving the movable member;
A liquid circuit kit for medical use, comprising:

Further, the liquid circuit system according to one embodiment of the present invention includes:
The medical liquid circuit kit,
An injector for detachably holding a syringe connected to the liquid circuit, and moving a piston member of the syringe to inject and suction liquid.
A switching device that holds a part of the liquid circuit and has a driving unit that moves the movable member of at least the first release valve;
Is provided.

In this specification, “connected” includes not only a state where a predetermined element is directly connected to an object but also a state where the predetermined element is connected via some other element.
“Connect in a T-shape” is intended to be connected so that the flow paths are branched, and does not limit the angle at which the lines intersect at all.
The “(contrast medium / saline) chamber” intends a container such as a bottle or a bag, and is not limited to a specific shape.

  According to the present invention, it is possible to provide a liquid circuit kit and a system capable of favorably performing angiography without requiring a complicated operation by an operator.

It is a figure showing typically the liquid circuit system of one form of the present invention. It is a schematic diagram which shows the function of a dual check valve. It is a figure which shows typically the switching machine which holds a part of liquid circuit kit. It is a figure showing typically the liquid circuit system of other forms of the present invention. It is a figure which shows a part of process of an angiography (aspiration of a contrast medium). It is a figure which shows a part of process of an angiography (extrusion of a contrast agent). It is a figure which shows a part of process of angiography (air clear). It is a figure which shows a part of process of an angiography (operation of a valve). It is a figure which shows a part of process of an angiography (extrusion of a contrast agent). FIG. 3 is a diagram showing a part of an angiography process (flash with physiological saline). It is a figure which shows a part of process of angiography (addition flash). It is a figure which shows a part of process of angiography (establishment of a blood route). It is a perspective view of the one-way valve with an opening function (disassembled state). FIG. 12 is a vertical sectional view of the one-way valve of FIG. 11, showing a state where a movable pin is projected. FIG. 12 is a vertical cross-sectional view of the one-way valve of FIG. 11, showing a state where a movable pin is pressed. It is an enlarged view which expands and shows a part of FIG. It is a perspective view showing the state where a support member, a movable pin, etc. were arranged in a casing main part. It is a perspective view which shows the internal structure of a casing main body. It is a perspective view of a movable pin. It is a perspective view of a support member. It is the perspective view which looked at the cap from the lower part. It is a figure which shows an example etc. of another pump apparatus which sends physiological saline. It is a figure which shows an example of a roller type pump typically. It is a figure which shows an example of a piston type pump typically. It is sectional drawing which shows the other example of a release valve. It is sectional drawing which shows another example of a release valve.

  Hereinafter, an embodiment of the present invention will be described with reference to the drawings. In the following description, terms indicating directions such as up, down, right, and left are used, but this does not limit the present invention in any way. Further, the contrast agent and the physiological saline may be simply referred to as “medical solution” or “liquid” without distinction.

  The liquid circuit system 200 of the present embodiment shown in FIG. 1 is used, for example, for a cardiac catheter test. The system 200 includes a liquid circuit kit 201 (described in detail below), a contrast medium chamber 221, a saline solution chamber 223, a transducer 270, and a syringe 251 connected thereto. The liquid circuit system 200 also includes an injection head 260 (only a part is shown) that holds the syringe 251 and suctions and pushes out a chemical solution.

  Specifically, the liquid circuit kit 201 of FIG. 1 includes a syringe line 204 connected to the syringe 251, a contrast medium line 205 connected to the contrast medium chamber 221, and a physiological saline connected to the physiological saline chamber 223. It includes a water line 206, a transducer line 207 connected to the transducer 270, a patient line 208 connected to a patient via a catheter (not shown), and a baseline unit 210 to which each of these lines is connected. I have.

  The material, length, and diameter of the tubes constituting each of the lines 204 to 208 may be appropriately selected in consideration of the pressure applied to the tubes. In a cardiac catheter test, a drug solution is injected at a relatively high pressure. Therefore, a portion to which a high pressure is applied is preferably formed of a high pressure-resistant tube. Similarly, it is preferable that the dual check valves 215A and 215B and the release valves 202A and 202B, which will be described later, also have high withstand pressure.

  As shown in FIG. 1, the “baseline section 210” refers to a portion to which each of the lines 204 to 208 is connected, and is configured by a tube, a valve, a connector, and the like. In this example, the syringe line 204 is connected to the upstream side of the baseline section 210, and the patient line 208 is connected to the downstream side. A contrast agent line 205, a physiological saline line 206, and a transducer line 207 are connected to an intermediate portion of the baseline 210 in order from the upstream side. Each of these lines 205 to 207 is connected to the baseline 210 in a T-shape.

  In the present embodiment, the contrast agent line 205 and the physiological saline line 206 are connected to the baseline unit 210 by dual check valves 215A and 215B, respectively. As an example, the two dual check valves 215A, 215B (details below) may use the same one or may use different ones having different functions. In FIG. 1, the same one is used as an example.

The dual check valves 215A, 215B are valves having the following functions (see also FIG. 2A):
(I) When the liquid is drawn toward the upstream side of the baseline 210 (that is, toward the syringe 251), the liquid is allowed to flow in that direction.
(Ii) On the other hand, with respect to the dual check valve 215A, when the liquid is pushed from the upstream side to the downstream side of the baseline 210, the liquid flows downstream through the valve 215A. Regarding the dual check valve 215B, similarly, when the liquid is pushed toward the downstream side, or when pushed from the physiological saline line 206 side toward the valve 215B, the liquid flows in those directions. .

  Further, the dual check valves 215A and 215B limit the flow from the downstream side to the upstream side and the flow toward the lines 205 and 206 as shown in FIG. 2A.

  In FIG. 1, another valve 215A is disposed upstream of the dual check valve 215B, and the flow of the liquid to the upstream side is restricted by the valve 215A. It will not be pulled to the side.

  As shown in FIG. 1, the transducer line 207 is connected to the baseline section 210 by a connector 217 without a valve function, for example. A three-way cock 213 is provided between the connector 217 and the dual check valve 215B. However, the arrangement position of the three-way cock 213 is not necessarily limited to this. As shown in FIG. 2C, the stopcock 213 may be located downstream of the air sensor 232 (details below) of the patient line 208.

  The three-way stopcock 213 is, for example, one in which one of three lines connected thereto along the direction of the lever is closed (for example, in the state of FIG. Is prevented). Such a three-way cock is used when the operator discharges the liquid in the line to the outside as necessary.

  Next, devices and the like connected to each of the lines 204 to 208 will be described. In addition, since these apparatuses can use a conventionally well-known thing, detailed description is abbreviate | omitted.

  The syringe 251 to which the syringe line 204 is connected may have a capacity of, for example, about several tens ml to 200 ml, and is preferably one capable of performing high-pressure injection. If necessary, a protective cover for covering the syringe 251 may be used. The syringe 251 has a cylindrical cylinder member and a piston member (plunger rod) slidably inserted into the cylinder member. The piston member may be a so-called rodless type.

  The injector (injection head) 260 to which the syringe 251 is detachably attached is not limited, but is preferably of a type that can perform, for example, high-pressure injection. The injector has a motor as a drive source and a presser member that moves back and forth. By pulling the presser member, the piston member of the syringe is pulled and the syringe is filled with the drug solution. On the other hand, by pressing the presser member, the liquid in the syringe is pushed out.

  The contrast agent chamber 221 to which the contrast agent line 205 is connected may be, for example, a bottle-shaped container filled with the contrast agent. The contrast agent chamber 221 may be used by being hung by a hanging tool (not shown). The contrast agent line 205 is connected to a lower portion of the contrast agent chamber 221. This connection may be made via a needle.

  As shown in FIG. 1, an air sensor 231 (for example, an infrared sensor) for detecting whether air is mixed in the liquid in the contrast agent line 205 is disposed below the contrast agent chamber 221. By detecting the air in the line with the air sensor 231, it is possible to detect that the chemical liquid in the chamber has run out. A drip chamber 233 is arranged below the air sensor 231 and on the contrast agent line 205, and the contrast agent from the contrast agent chamber 221 is once dropped into the chamber 233, and the contrast agent is It flows into the line 205.

  The physiological saline chamber 223 to which the physiological saline line 206 is connected may be, for example, a bag-shaped container filled with a contrast agent. In this example, a pressurizing unit 224 for pressurizing the bag is further provided. (The one having such a configuration is also referred to as a “pressurized bag”). A commercially available pressure bag may be used. The pressurizing means 224 may be, but is not limited to, a device that compresses the bag using a fluid such as air as a driving source, or a device that compresses the bag using a motor or the like as a driving source. Is also good. Similar to the contrast agent line 205, a similar air sensor 231 and a drip chamber 233 are arranged in the physiological saline line 206. The mechanism for pressurizing the physiological saline is not limited to the above, but other configurations will be described later.

  The physiological saline line 206 is provided with a release valve 202A for switching the line 206 between open and closed. One specific configuration example of the release valve 202A will be described later with reference to FIGS. The release valve 202A has a movable member 203 that moves by receiving an external force. By moving the movable member 203, a valve opening / closing state is switched to open and close the saline line 206. In the present embodiment, as an example, the valve 202A is opened by pressing the movable member 203, and the physiological saline from the pressurized bag flows to the baseline 210 side.

  Next, devices and the like connected to the transducer line 207 will be described. The transducer 270 connected to the line 207 is used to detect a blood pressure and monitor a pulse of the patient, for example. As an example, the pulse waveform is configured to be displayed on a display 271 connected to the transducer 270.

  The transducer line 207 is also provided with a release valve 202B similar to the release valve 202A of the physiological saline line 206. However, the direction is opposite to that of the release valve 202A. In this release valve 202B, by pressing the movable member 203, a state in which the chemical solution can flow toward the transducer 270 is established.

In the example of FIG. 1, a three-way cock 213 is disposed between the release valve 202B of the transducer line 207 and the transducer 270. The movable member 203 of one release valve 202A and the movable member 203 of the other release valve 202B are arranged so as to face each other. Further, the distances (L ₁ , L ₂ ) from the baseline 210 to the movable members 203 of the respective valves are arranged not to be the same so as to correspond to the configuration of the switching device 300 described later.

  A thin tube called a catheter (not shown) is connected to the distal end of the patient line 208, and this catheter is inserted into a blood vessel of a patient. In a cardiac catheterization test, the tip of the catheter is transferred to, for example, a coronary artery, and a contrast agent or the like is injected into the blood vessel from the tip of the catheter.

  Subsequently, a switching device 300 for holding a part of the liquid circuit kit 201 of FIG. 1 and appropriately switching its flow will be described with reference to FIG. 2B. The switching device 300 includes a box-shaped housing 310 as an example. The switching device 300 has a first holding unit 306 for holding a part of the physiological saline line 206 and a second holding unit 307 for holding a part of the transducer line 207. These holding portions 306 and 307 are formed in a concave shape, and are configured such that release valves 202A and 202B of each line are set therein.

  Inside the housing 310 of the switching device 300, there are provided driving units 301, 301 for pressing the movable members 203, 203 of the valves 202A, 202B electromechanically using, for example, a motor as a driving source. The driving units 301 may be configured to operate in response to a control signal from an external controller 350. Although the function of the controller 350 is not particularly limited, the injector 260 may have the function.

  The switching device 300 also has a third holding unit 308 that holds a part of the patient line 208 and an air sensor 332 for detecting the presence or absence of bubbles in the patient line 208. The air sensor 332 may be of an ultrasonic type as an example. The ultrasonic sensor 332 is more advantageous than an infrared sensor or the like in that even if bubbles are mixed in a liquid under high pressure conditions, they can be detected well.

  Hereinafter, a method of using the liquid circuit kit 200 of the present embodiment configured as described above will be described.

  FIG. 3 shows an initial state. In this state, the movable members 203 and 203 of the release valves 202A and 202B are not pressed and the liquid does not flow in both directions. In the state of FIG. 3, when the operator presses a predetermined button (air clear button) of the injector 206, the piston drive mechanism operates to pull the piston member of the syringe 251. As a result, the inside of the syringe 251 and the syringe line 204 becomes a negative pressure, and the contrast agent in the chamber 221 is drawn into the syringe lines 205 and 204 and the syringe 251 via the contrast agent line 205 and the dual check valve 215A.

  Next, as shown in FIG. 4, this time, the piston member of the syringe 251 is pushed, and the contrast agent is pushed out of the syringe 251. The fluid is sent to the baseline section 210 side through the syringe line 204 and passes through the two dual check valves 215A and 215B to fill the baseline section 210. This operation of pushing out the contrast agent is continued until the contrast agent is pushed out at least so as to exceed the dual check valve 215B as shown in FIG.

  Next, as shown in FIG. 5, the movable member 203 of the release valve 202A and the movable member 203 of the release valve 202B are pushed to open both valves 202A and 202B. This opening is automatically performed by the driving units 301 and 301 of the switching device 300 pressing each movable member. At this point, the pressurizing means 224 of the physiological saline chamber 223 is driven, and a predetermined pressure (for example, about 300 mmHg) is applied to the physiological saline. Therefore, when the valve 202A is opened, the physiological saline flows from the chamber 223 toward the baseline 210, passes through the release valve 202A and the dual check valve 215B, and flows toward the patient line 208. The contrast agent further passes through the stopcock 213 and branches off at the connector 217, partly flowing into the patient line 208 and partly into the transducer line 207. Here, since the release valve 202B is open, the saline flows toward the transducer 270 beyond the release valve 202B. By filling each line with the physiological saline in this manner, air bubbles in the lines are removed to the outside.

  Next, as shown in FIG. 6, the pressing of the movable member 203 of the release valve 202A of the physiological saline line 206 is released, so that the physiological saline does not flow downstream beyond the release valve 202A. Further, in the next contrast agent injection step, the pressing is also released on the movable member 203 of the release valve 202B of the transducer line 207 so that the contrast agent does not flow into the transducer 270 side, and the contrast agent or the like exceeds the release valve 202B. Do not flow to the transducer side.

  Next, by operating the piston drive mechanism of the injector 206 to push the piston member of the syringe 251, the contrast agent in the syringe 251 is pushed toward the patient as shown in FIG. 7. Specifically, the contrast agent passes through a contrast agent line 204, a baseline unit 210, a patient line 208, and a catheter (not shown) to a predetermined imaging site (for example, a coronary artery of the heart) in the patient. Sent.

  Next, after the contrast agent is injected and the residual pressure in the circuit is sufficiently reduced, the movable member 203 of the release valve 202A of the physiological saline line 206 is pushed to open the valve again, as shown in FIG. At this point, a predetermined pressure (for example, about 300 mmHg) is applied to the physiological saline by the pressurizing means 224 of the pressurizing bag, as in the above-described process. Is sent out to the baseline section 210 and the patient line 208, and the contrast medium is flushed.

  Then, if necessary, as shown in FIG. 9, the release valve 202B of the transducer line 207 is opened, thereby flowing the physiological saline also to the transducer side with respect to the release valve 202B. Flash by

  Thereafter, as shown in FIG. 10, the pressing of the movable member 203 of the check valve 202A of the physiological saline line 206 is released, so that the physiological saline does not flow over the valve 202A to the baseline 210 side. Thereby, the pressurized state of the physiological saline on the downstream side of the baseline section 210 is released. As a result, as shown in FIG. 10, a blood route is established through the patient line 208 and the transducer line 207, and the blood pressure can be detected by the transducer 270.

  As described above, the liquid circuit kit 201 of the present embodiment includes the contrast agent line 205, the physiological saline line 206, the syringe line 204, the patient line 208, and the baseline unit 210, and includes the contrast agent line Dual check valves 215A and 215B for restricting the flow of the liquid in a predetermined direction are provided at a connection between the 205 and the baseline 210 and a connection between the physiological saline line 206 and the baseline 206. Therefore, it is possible to satisfactorily perform the suction of the contrast agent into the syringe 251 (FIG. 3) and the subsequent delivery of the contrast agent (FIG. 4) without the operator having to manually switch the three-way cock. Can be.

  In the liquid circuit kit 201 of the present embodiment, a release valve 202A is provided in the saline line 206. In particular, since the release valve 202A switches between opening and closing by pressing the movable member 203, the switching operation is easier to perform as compared with a type that switches between opening and closing by twisting a lever such as a three-way cock. Specifically, there is an advantage that automatic switching by a switching device using an actuator such as a motor can be easily performed. Further, such movement of the movable member 203 can be performed in a shorter time than in the case where the lever is twisted. Further, in the case of a configuration in which the flow path is closed by the function of the release valves 202A and 202B itself as in the present embodiment, the closing can be performed more reliably than, for example, a configuration in which the tube is closed by closing.

  Further, in the configuration of the present embodiment, since the transducer line 207 can be satisfactorily closed using the release valve 202B, even when performing high-pressure injection such as a cardiac catheterization test, the high-pressure liquid transducer 270 is used. Thus, the inflow to the side can be prevented, and the breakage and damage of the transducer 270 can be prevented.

  As an example, the liquid circuit kit 201 of the present embodiment uses the contrast agent line 205, the physiological saline line 206, the syringe line 204, the transducer line 207, the patient line 208, and the baseline unit 210 as one set, and is used as a disposable. May be used. That is, the liquid circuit kit 200 can be used a plurality of times, but may be replaced with a new one at the end of use for one patient for the purpose of preventing infectious diseases and the like. In this case, it may be disposable including the intravenous chambers 233 and 233 (only one of them is allowed) of the physiological saline line 206 and the contrast medium line 205.

  The liquid circuit system according to the present embodiment utilizes the liquid circuit kit 200 described above, and includes an injector mounted with a syringe 251 for suctioning and injecting (dispensing) liquid, and a predetermined line of the liquid circuit kit 200. And a switching device 300 that automatically switches the opening and closing of the switch. According to such a system, a series of injection operations of the contrast agent and the physiological saline can be appropriately performed without the operator having to switch the three-way stopcock or the like. Can be automatically performed.

  The invention is not limited to the embodiments described above. For example, instead of the pressurized bag, a tube pump may be used instead of the pressurized bag, in which the tube is continuously crushed and the saline in the tube flows in a predetermined direction. Alternatively, a device that repeats suction and extrusion of physiological saline by reciprocating a piston member of a small syringe can be used. This device uses a cam mechanism and a biasing member (for example, a spring). You may.

[Specific example of release valve]
The release valves 202A, 202B available for the liquid circuit system 200 of FIG. 1 may be specifically as follows. Hereinafter, one configuration example of the release valve will be described with reference to FIGS. 11 to 19, but the present invention is not limited to the following steps. In the following, the one corresponding to the release valves 220A and 220B will be described as "one-way valve 1". The movable member 223 corresponds to the “movable pin 60”.

  Note that the one-way valve shown in FIGS. 11 to 19 switches between a state of the one-way valve that allows only one-way movement of the chemical solution and an open state that allows two-way movement. The release valve may switch between a closed state in which the movement of the liquid is completely shut off and an open state in which the movement in both directions is allowed (the direction in which the liquid flows depends on the pressure difference of the liquid). Good.

  The one-way valve 1 of the present embodiment shown in FIG. 11 is mainly used for a medical liquid circuit. In particular, the one-way valve 1 has a high pressure resistance and can be used, for example, for cardiac catheterization. On the other hand, as shown in FIGS. 11 and 12, the valve 1 moves to a casing 50 forming the valve chamber 10, a disc-shaped valve body 25 disposed in the valve chamber 10, and a part of the casing 50. The movable pin 60 is provided so as to be capable of being held, and a cap 70 attached to the casing 50 so as to cover the movable pin 60.

  The one-way valve 1 is connected to a supply tube P1 and a discharge tube P2. On the other hand, the valve 1 basically allows only a flow from the supply tube P1 to the discharge tube P2, and allows a bidirectional flow only while the movable pin 60 is pressed. In addition, since the flowing direction of the chemical solution depends on the pressure of the chemical solution in the tubes P1 and P2, other flow directions are possible under a predetermined pressure condition. As an example, under the condition that the liquid pressure on the P2 side is higher than the P1 side, the chemical does not flow when the movable pin 60 is not pressed, and the chemical flows from the P2 side toward the P1 side only while the movable pin 60 is pressed. It will flow.

  Although not limited, each component of the casing 50, the movable pin 60, the cap 70, and the support member 21 described below may be a resin molded product as an example.

  As shown in FIGS. 11 and 12, the casing 50 has a casing body 40 to which the supply tube P1 is connected, and a substantially cylindrical closure member 30 to which the discharge tube P2 is connected. When the closure member 30 is attached to the casing body 40, the valve chamber 10 is formed between the two members. An inlet 11 for supplying a chemical solution into the valve chamber is formed on the upstream side of the valve chamber 10 (FIG. 12), and an outlet 13 for sending the chemical solution to the outside is formed on the downstream side. .

  The valve chamber 10 has a substantially cylindrical shape in the horizontal direction, and its downstream side is tapered so that the cross-sectional area gradually decreases toward the outlet 13 side. In the valve chamber 10, a valve body 25 (detailed below) for opening and closing the inlet 11 and a support member 21 (detailed below) for holding the valve 25 are arranged.

  The shape of the casing body 40 will be described in detail with reference to FIG. As shown in FIG. 15, the casing main body 40 is a cylindrical (one example) main body part 41 that forms the valve chamber 10 and a cylindrical part that is thinner than the main body part 41 provided on the upstream side thereof. And a tube holding portion 48 to which P1 is connected. The material of the casing body 40 is not limited, but may be permeable so that the inside of the valve can be seen, or may be non-permeable.

  The end of the supply tube P1 is inserted into the tube holding section 48. The supply tube P1 is connected to the inside of the tube holding portion 48 with sufficient strength by a conventionally known method so that the tube does not come off even if the liquid pressure rises. One or more ribs may be formed on the tube holding portion 48 so that the supply tube P1 can be connected with good workability. In this example, ribs 49f, 49f projecting in the radial direction are formed one by one on the upper part and the lower part of the cylindrical part 49.

  As shown in FIGS. 15 and 16, the main body 41 has a shape in which a cylinder is turned sideways, and a valve body 25 (see FIG. 11) and a support member 21 that presses the valve body 25 are arranged therein (see FIGS. 15 and 16). The details of the members described below). As shown in FIG. 16, an inlet 11 for supplying a chemical solution is formed in a part of the wall surface 41h in the main body.

  In this example, a concave portion 11a (see FIGS. 14 and 16) formed so as to partially depress the wall surface 41h is provided in the inlet portion 11, and a flow path 11c communicates with the concave portion 11a. . As shown in FIG. 14, a chamfer surface 11b is formed at a boundary between the concave portion 11a and the flow path 11c. Further, as shown in FIG. 16, the contour of the concave portion 11a is circular, and three ribs 43Ra are formed in the concave portion 11a as an example. These ribs 43Ra are radially formed at equal intervals. The rib 43Ra serves to support the front surface of the valve body 25 (described in detail below).

  As shown in FIG. 16, a plurality of support ribs 43 </ b> Rb for supporting the outer peripheral portion of the valve body 25 are formed around the inlet 11. As an example, six support ribs 43Rb are radially arranged at equal intervals from each other.

  As shown in FIG. 11, the valve body 25 is, for example, disc-shaped and flexible (a valve body having no flexibility will be described later). The thickness of the valve body may be uniform. The material of the valve body may be, for example, silicone rubber, and its hardness is, for example, in the range of 5 ° to 90 °, preferably in the range of 40 ° to 80 °, and more preferably in the range of 60 ° to 80 °. It may be a range. The valve body 25 has a diameter that can close the inlet 11.

  As shown in FIG. 18, the support member 21 for holding the valve body 25 includes a ring-shaped frame 27, a substantially cone-shaped (conical) holding portion 23 disposed at the center thereof, and a holding portion 23. It has four (one example) support arms 26 that connect the frame 27 and support the holding portion 23. The pressing portion 23 protrudes toward the valve body 25, and the front end thereof presses the vicinity of the center of the back surface of the valve body 25.

  According to such a support method by the support member 21, the vicinity of the outer peripheral portion of the valve body 25 is not restrained, so that it can be elastically deformed freely. The valve element 25 basically closes the inlet 11 as shown in FIG. 12 and prevents the flow from the valve chamber 10 toward the supply pipe P1. On the other hand, when the liquid chemical is supplied from the supply pipe P1, the outer peripheral portion of the valve body 25 is elastically deformed by the liquid pressure, thereby allowing the liquid chemical to flow into the valve chamber 10.

  Returning to the description of the support member 21 again. As shown in FIG. 18, the support member 21 has an R-shaped or tapered shape so that even if air bubbles enter the valve chamber, the air bubbles can be satisfactorily discharged outside the valve chamber. ing. Specifically, a gentle R shape is formed on the upstream side in the flow direction of each support arm 26. The frame 27 also has a tapered shape such that the thickness of the frame becomes thinner toward the upstream side in the flow direction. According to such a configuration, there is an advantage that bubbles can easily flow to the downstream side as compared with the case where the cross-sectional shapes of the support arm 26 and the frame 27 are simple rectangles.

  The operation for removing the air bubbles is not limited, but, for example, the user may raise the entire valve 1 so that the discharge tube P2 side faces upward and tap the valve lightly with the hand or a predetermined tool by the user. May be used to release bubbles to the downstream side. When the material of the casing 40 is transparent, it is possible to visually recognize whether or not bubbles remain in the casing. Furthermore, when the downstream side of the valve chamber 10 is formed in a tapered shape in which the cross-sectional area gradually decreases toward the outlet portion 13 as in the present embodiment, air bubbles can be satisfactorily released to the outside.

  As a modified example of the above configuration, instead of the R shape of each support arm 26, its cross-sectional shape may be tapered such that the plate thickness becomes thinner toward the upstream side in the flow direction. Further, the frame 27 may be provided with an R shape.

  FIG. 12 is referred to again. The support member 21 has a configuration in which the outer peripheral portion is sandwiched and supported between the casing body 40 and the closure member 30. According to such a configuration, there is no need to provide a dedicated component or structure for fixing the support member 21. In order to prevent the support member 21 from rotating in the valve chamber 10, a projection 27a is formed on the outer periphery of the frame 27 as shown in FIGS. It may be adapted to engage with the longitudinal groove 43g.

  In addition, in order to prevent air bubbles from staying in the valve chamber 10, in the present embodiment, the distal end of the movable pin 60 also has a predetermined shape, which will be described later.

  Next, the movable pin 60 and a structural portion where the movable pin 60 is arranged will be described. As shown in FIG. 12, the housing space 15 in which the movable pin 60 is arranged is formed by an outer cylinder portion 45 (details described below) of the casing main body 40 and a cap 70 attached thereto.

  The cap 70 has a substantially bottomed cylindrical shape as a whole as shown in FIGS. 12 and 19, and in this example, a flat upper surface portion 71 and a cylindrical peripheral wall portion extending downward from its peripheral portion. 73. The upper surface portion 71 is provided with one opening, through which a part of the movable pin 60 protrudes to the outside. As shown in FIG. 19, a convex portion 76 (for example, a rectangular cross section is formed) is formed on the inner surface of the peripheral wall portion 73. In this example, one convex portion 76 is provided on each side of the peripheral wall portion 73.

  In the present embodiment, the cap 70 is attached to the casing body 40 with sufficient strength so that the cap 70 and the movable pin 60 do not come off even when a high pressure is applied to the chemical solution during use. As a means for fixing the cap 70, for example, an adhesive or welding may be used, but a mechanical fixing means is more preferable. As the mechanical fixing means, for example, one in which a convex portion of one member fits into a concave portion of the other member, one in which screw portions are screwed together, or an additional fixing device such as a screw or a fixing pin is used. Alternatively, both members may be fixed.

  In the present embodiment, as an example, a configuration in which the convex portion 76 (see FIG. 19) inside the cap 70 is engaged with an L-shaped groove 45g (see FIG. 14) formed on the outer periphery of the outer cylindrical portion 45 of the casing. It has become. According to such a fixing method, the cap 70 can be fixed with sufficient strength and with high positional accuracy. If necessary, after the cap 70 is attached to the outer cylinder 45, the cap 70 may be further fixed with an adhesive or the like.

  Next, the movable pin 60 will be described. As shown in FIG. 17, the movable pin 60 has, as an example, a shaft portion 61 having a circular cross-sectional shape, and a flange portion 67 formed on a part thereof. An operating portion 63 that is in contact with the valve body 25 is formed on the distal end side (lower end side) of the shaft portion 61.

  As shown in FIG. 14, the action portion 63 is formed in a wedge shape so that the outer peripheral portion of the valve body 25 can be raised from the wall surface 41h. Specifically, the action portion 63 has a protrusion 63a that enters between the valve body 25 and the wall surface 41h, and a flat portion 63b formed downstream of the protrusion 63a. The flat portion 63 is preferably configured to be flush with the upper surface of the valve chamber 10 or protrude from the upper surface of the valve chamber 10 in a state where the movable pin 63 is positioned above as shown by the broken line in FIG. If the flat surface 63 is at a position recessed from the upper surface of the valve chamber, there is a possibility that air bubbles may stay in this portion. However, with the above configuration, air bubbles can be favorably flowed to the downstream side. it can.

  Referring to FIG. 17 again, the shaft portion 61 is formed with an annular groove 61c for fitting an O-ring R1 (described in detail below). The flange 67 is formed above the annular groove 61c, and the flange 67 has four arc-shaped guide holes 67a. The upper end of the shaft portion 61 is a portion pressed by a user or by a predetermined mechanism, and a corner portion on the outer periphery of the upper end has an R shape.

  As shown in FIG. 5, the movable pin 60 is disposed inside the outer cylinder 45 of the casing main body 41. An inner cylinder part 46 is formed inside the outer cylinder 45, and the inner cylinder part 46 is constituted by four wall pieces 46a having a circular cross section. When the movable pin 60 is set in the outer cylindrical portion 45, each wall piece 46a is in a state of being passed through each guide hole 67a of the movable pin. Each of the wall pieces 46a functions as a member for guiding the vertical movement of the movable pin 60, and also serves to prevent the movable pin 60 from rotating around the central axis.

  The movable pin 60 configured as described above is configured to be able to move up and down as shown in FIGS. First, the state of FIG. 12 in which the movable pin 60 is at the first position (upper position) will be described.

  In this state, the movable pin 60 is lifted upward by the urging force of the coil spring 68 disposed below the flange 67 of the movable pin 60, and the upper surface of the flange 67 is pressed against the inner surface of the cap 70. Since the flange 67 is formed to have a larger diameter than the opening of the cap 70, the movable pin 60 does not fall out of the cap. In the present embodiment, since the upper surface of the flange 67 and the inner surface of the cap 70 are both flat surfaces so that both members are in contact with each other, the cap 70 uniformly applies the force from the flange 67. Can receive.

  When the movable pin 60 is at the first position, the action portion 63 of the movable pin 60 separates from the valve body 25, and the valve body 25 closes the inlet 11. In this state, the one-way valve 1 functions as a one-way valve that allows only the flow from the supply tube P1 side to the discharge tube P2 side. As described above, the flow direction of the chemical solution depends on the pressure of the chemical solution in the tubes P1 and P2. For example, the valve 1 is used in a liquid circuit in which the fluid pressure on the P2 side is higher than that on the P1 side. In this case, the chemical does not flow when the movable pin 60 is not pressed, and the chemical flows from the P2 side toward the P1 side only while the movable pin 60 is pressed. In the one-way valve 1 of the present embodiment, the flow of the chemical solution is not limited to a specific direction.

  On the other hand, in FIG. 13, the movable pin 60 is pushed downward, and has moved to the second position (the lower position). The movable pin 60 is pushed down against the urging force of the coil spring 68, and when it is moved to the position shown in FIG. 13, the action portion 63 of the movable pin 60 enters between the valve body 25 and the wall surface 41h (FIG. 14). ), The outer peripheral portion of the valve body 25 is elastically deformed, whereby the inlet portion 11 is opened. As a result, the liquid medicine can flow in both directions (in which direction the liquid flows depends on the liquid pressure in P1 and P2). When the pressing of the movable pin 60 is stopped in the state of FIG. 13, the movable pin 60 returns to the first position again by the urging force of the coil spring 68, the valve body 25 returns to the original shape, and the inlet 11 is closed. , Valve 1 functions as a one-way valve.

  As described above, in the one-way valve 1 of the present embodiment, by pressing the movable pin 60, the communication state of the valve can be appropriately switched. The means for pushing the movable pin 1 is not particularly limited. For example, the user may push the movable pin 60 by hand or using a predetermined tool, or a predetermined mechanism may push the movable pin 60. Is also good.

  With reference to FIGS. 12 and 13, the description of the assembly state of the valve will be added. An O-ring R <b> 1 is fitted to the movable pin 60, whereby the sealing between the movable pin 60 and the inner cylindrical portion 46 is improved. Is secured. In the case of such a configuration, a radial outward force is applied to the inner cylindrical portion 46 by receiving the force from the O-ring R1, but in the present embodiment, as shown in FIG. Is formed so that the tip of each of the wall pieces 46a is fitted into a locking groove 71g formed on the inner surface of the upper surface 71 of the cap 70. Therefore, the distal end side of the inner cylindrical portion 46 is prevented from expanding, and as a result, the sealing performance of the O-ring R1 is kept good even during use.

  On the other hand, the specific material of each component constituting the valve 1 is not particularly limited, but as an example, the movable pin 60 may be a polyacetal resin (POM) having good slidability. The components constituting the casing 50 may be, for example, polycarbonate resin (PC). If necessary, the outer peripheral surface (particularly, the surface facing the wall surface 41h) of the valve body 25 may have a fine uneven shape.

  As described above, the one-way valve 1 of the present embodiment can temporarily release the function as the one-way valve by moving the movable pin 60. The movable pins 60 are arranged in the storage space 15 so that the movable pins 60 do not fall out of the cap 70. Therefore, even if the pressure of the drug solution increases during use and a large force is applied to the movable pin 60 in a direction to push the movable pin 60, the force is received by the cap 70 via the flange 67, so that the movable pin 60 is movable. The pin 60 does not come off. Therefore, the one-way valve 1 of the present embodiment can satisfactorily cope with high-pressure injection of a chemical solution.

  Further, in the present embodiment, the cap 70 is fixed to the casing 50 using mechanical fixing means (45g, 76). For this reason, the cap 70 can be fixed with sufficient strength and with high positional accuracy as compared with a case where the cap 70 is fixed using only an adhesive, for example.

  Further, in the present embodiment, since the concave portion 11a as shown in FIG. 16 is formed in the inlet portion 11 of the valve chamber 10, the inlet portion 11 can be reliably opened only by slightly deforming the valve body 25. it can. That is, if such a concave portion 11a is not formed, in order to open the inlet portion 11, it is necessary to deform the valve body 25 to such an extent that the central flow passage 11c is opened. On the other hand, according to the configuration of the present embodiment, as shown in FIG. 16, when the outer peripheral portion of the valve body 25 is deformed, the concave portion 11a is opened and the flow path 11c communicating therewith is opened. The opening and closing of the inlet portion 11 can be performed with a slight deformation of the valve body 25.

  On the other hand, when the concave portion 11a is provided in this manner, there is a problem with the hydraulic pressure applied to the back surface of the valve body 25 when the valve is used. That is, although it differs depending on the type of liquid circuit in which the valve 1 is used, if the liquid pressure in the valve chamber 10 becomes extremely high at the time of use, the valve pressure causes the valve body 25 to move toward the concave portion 11a side. It is assumed that it will be pushed to. In this case, if the support rib 43Ra is not provided in the concave portion 11a, a state in which the valve body 25 is stuck to the concave portion 11a may occur. In this state, even if the action portion 63 of the movable pin 60 is pushed between the valve body 25 and the wall surface 41h, there is a possibility that the inlet portion 11 is not sufficiently opened. On the other hand, if the support rib 43Ra is formed in the concave portion 11a as in the present embodiment, it is possible to prevent the valve body 25 from sticking to the concave portion 11a, and to operate the movable pin 60. Thereby, the inlet 11 can be opened and closed well. The shape of the support rib 43Ra is not necessarily limited to the shape as shown in FIG.

As described above, one embodiment of the present invention has been described with reference to the drawings. However, the present invention is not limited to the above, and can be variously modified.
For example, in the above description, an example has been described in which the valve body 25 has flexibility and its outer peripheral portion is elastically deformed. However, the valve body 25 may not have flexibility. For example, the valve body is a plate-like member having no flexibility, and is configured to be displaceable between a position (a) for closing the inlet 11 and a position (b) for opening the inlet 11. May be. When the movable pin 60 is pressed, the valve body is displaced to the position (b), whereby the inlet 11 is opened. In this case, the support member 21 may have a configuration in which at least the pressing portion 23 has elasticity and the pressing portion elastically contracts to allow the displacement of the valve body.

  The shape of the pressing portion of the support member is not limited to the conical shape, and may be, for example, a truncated conical shape. With such a shape, the valve body can be pressed over a wider area.

  The shape of the cap 70 is not particularly limited as long as the cap 70 is fixed to the casing 50 with sufficient strength so that the movable pin 60 does not come off when the one-way valve 1 is used. It may be shaped.

  The shape of the movable pin 60 is not limited as long as it moves by receiving an external force and thereby moves the valve body 25, and may have a shape other than the pin shape. In the case of a pin shape as in the present embodiment, the cross-sectional shape is not limited to a circle, but may be a rectangle, a polygon, or the like. Further, as the structure for preventing the movable pin 60 from coming off, in the above-described embodiment, the structure in which the flange portion 67 of the movable pin 60 abuts on the upper surface of the cap 70 has been described, but the structure for preventing the coming off is limited to the flange. Instead, it may be a simple projection provided on the outer periphery of the movable pin. Further, an additional cap (not shown) may be attached to the protruding portion of the movable pin 60 so that the user can easily push the movable pin 60 by hand.

  In the above example, the casing 50 is composed of the casing main body and the closure member 30, but the number of parts and the shape of the casing are not limited as long as the casing forms the valve chamber 10.

  The valve body 25 is not limited to a circular contour, and may have an elliptical, rectangular, or polygonal contour. In the above description, the thickness of the valve body 25 is assumed to be constant. However, the thickness of the valve body 25 may be different depending on the part.

(Other functions of valve)
Further, the one-way valve according to another embodiment of the present invention may be as follows.

A casing forming a valve chamber having a liquid inlet and an outlet,
A valve body arranged to close the inlet in the valve chamber, and configured to be elastically deformable or displaceable to open the inlet,
A movable member movably held by the casing, the movable member being in contact with the valve body by moving to elastically deform or displace the valve body;
With
A one-way valve with an opening function, wherein when the movable member is pushed, an amount of the chemical corresponding to the amount of movement is pushed out of the valve chamber through the outlet.

  This valve will be described with reference to FIG. The valve is configured such that when the movable pin 60 is pressed, a small amount of the chemical corresponding to the amount of movement is pushed out of the valve chamber 10. On the other hand, when the pressing of the movable pin 60 is stopped, the movable pin 68 is returned to the original position by the coil spring 68, and the valve body 25 is temporarily deformed to refill the valve chamber 10 with the drug solution again. As described above, the function of pushing out a small amount of the drug solution by operating the movable pin 60 is particularly effective when a contrast medium is injected, for example, in a cardiac catheterization test. That is, in this type of examination, a catheter is inserted into the patient's blood vessel, but if the valve has the above function, a small amount of contrast medium can be output from the tip of the catheter As a result, for example, it is possible to satisfactorily confirm where the tip of the catheter is currently in the patient.

(About PIT type pump device)
In the drug solution circuit system according to the present invention, a pump device 226 as shown in FIG. 20 may be used instead of the pressurizing means 224 for physiological saline (FIG. 1). FIG. 20 shows only a part of the chemical liquid circuit system. Regarding the configuration downstream of the three-way cock 213, the same one as in FIG. 1 can be used.

  The pump device 226 is of a type disclosed in, for example, Japanese Patent No. 3626264. The pump device 226 includes a main body 227 on which a small syringe 226a is mounted, and a piston drive mechanism (not shown) for moving a piston member of the syringe 226a forward and backward.

  In order to realize the transportation of the physiological saline by the pump device 226, in the configuration of FIG. 20, a part of the circuit is changed from that of FIG. Specifically, connectors 215C and 215D are used instead of check valves 215A and 215B, and one valve V-1 is arranged between both connectors. In addition, the one-way valve V-1 is arranged so as to allow the flow to the downstream side and not to allow the flow in the opposite direction, as shown by the triangle mark in FIG. The flow restriction direction of the other one-way valve also follows the direction of the triangular mark in FIG.

  On a line 205 connecting the connector 215C and the contrast agent chamber 221, a connection connector 234, a drip chamber 233, an air sensor 231, and a one-way valve V-2 are arranged in this order from the side near the chamber 221. The arrangement of these components 234, 233, 231 can be changed as appropriate.

  The line 206 connecting the connector 215D and the physiological saline chamber 223 is divided into two lines in the middle, one of which is the line 206, and the other is the line 209 which goes to the pump device 226. As shown in FIG. 20, two one-way valves V-3 and V-4 are arranged on the line 206.

One one-way valve V-5 is also provided between the connector 215D and the three-way cock 213. In addition, the one-way valve V-5 may be omitted. If there is a one-way valve V-5, a circuit downstream of the one-way valve may be made disposable. Alternatively, a circuit downstream of the connector 215D may be used as a disposal regardless of the presence or absence of the one-way valve V-5.
Alternatively, a chemical tube (not shown) may be connected to the three-way cock 213, and the medical solution may be injected toward the patient via the chemical tube.

  In the chemical liquid circuit system of FIG. 20 configured as described above, the pump device 226 is operated to move the piston member of the small syringe 226a forward and backward, so that (i) the saline solution from the chamber 223 into the syringe 226a. The suction and (ii) discharge of the physiological saline from the small syringe 226a are repeated. Thereby, the physiological saline is injected toward the patient.

  In the configuration of FIG. 20, a load sensor 223S for measuring the weight of the physiological saline chamber 223 is provided as an example. Based on the output value of the load sensor 223S or a value obtained by converting the output value into a load, a control device (not shown) determines whether or not the value is equal to or less than a predetermined set value (that is, a reference value having a remaining amount of the physiological saline). Is determined as follows). When it is determined that the value is equal to or smaller than the predetermined set value, a predetermined warning (for example, lighting of a lamp, display of a message, output of sound or voice, etc.) is issued to the operator.

  Naturally, the load sensor 223S as described above can be used in the chemical liquid circuit system of the embodiment in FIG.

  For example, in order to omit the air sensor 231 in the chemical liquid circuit system shown in FIG. 20, a connector having a floating valve element as disclosed in Japanese Patent Application Laid-Open No. HEI 9-117505 can be used as an example of the drip chamber. Thus, air is prevented from entering the patient line. Further, it may be determined whether or not the valve body is empty based on the position of the valve body, and if empty, control such as stopping injection may be performed.

The chemical circuit system of FIG. 20 includes the following liquid circuit kit:
A medical liquid circuit kit used for angiography,
A contrast agent line connected to the contrast agent chamber;
A saline line connected to the saline chamber;
A syringe line connected to the syringe,
A patient line for delivering a contrast or saline solution to the patient,
A baseline portion to which each line is connected, wherein the contrast agent line and the physiological saline line are each connected in a T-shape,
And,
a: (i) when the liquid is drawn toward the upstream side of the baseline, the contrast agent flows from the line into the baseline, and (ii) the liquid flows from the upstream of the baseline. First valve means (V-1, V-2) configured to pass liquid through the valve means in that direction when pushed toward the downstream side;
b: The second valve means (V-1) which allows the liquid to flow in the direction when the liquid is pushed from the upstream side to the downstream side of the baseline portion, but does not allow the liquid to flow in the opposite direction. When,
c: Third, when the saline is sent from the saline chamber by the means for sending the saline, the saline is allowed to flow toward the patient line, and the saline is not allowed to flow toward the syringe line. Valve means (V-3, V-1);
A liquid circuit kit for medical use, comprising:

(About roller type pump device)
A roller pump 470 as shown in FIG. 21 can be used as a means for pressurizing the chemical solution chamber and sending out the chemical solution. The pump 470 has, for example, a pair of pressing members 471 and 472 arranged so as to sandwich the chamber 223. When one of the pressing members 471 and 472 approaches the other, the chamber 223 between the two members 471 and 472 is pressed, whereby the chemical solution inside the chamber 223 is extruded.

  Although the specific structure can be designed or changed as appropriate, as an example, both members may be connected by a hinge part 474, and one may rotate with respect to the other. A roller 476 may be provided to bring one member closer to the other. The roller 476 moves downward as shown by the arrow while rotating around the rotation center 476a (with or without a driving source), and moves the pressing member 471 toward the other member 472. It may be configured to press.

(About piston type pump device)
Further, a piston type pump 480 as shown in FIG. 22 can be used. This pump 480 includes two syringes 481 and 486 connected in series, and the distal end of the front syringe 481 is connected to the line 209 (see FIG. 20). A short gasket 482a is slidably disposed in the front syringe 481, and a projection 485 is formed on the back surface of the gasket 482a. The projection 485 does not necessarily have to be formed, but plays a role in defining a movable range when the gasket 482a moves backward.

  The distal end of the rear syringe 486 is formed long and thin, and is inserted into a through hole formed in the sealing member 482b of the front syringe 481. Thereby, the liquid or gas in the rear syringe 486 is sent to the front syringe 481 and is sucked from the syringe 481. The pump 480 is also provided with a driving means (not shown) for moving the piston member of the rear syringe 486 forward and backward.

  In the chemical liquid circuit system according to the present invention, it is also possible to use the pump device 480 of the type shown in FIG.

(Other configurations of release valve)
23 may be used as the release valves 202A and 202B in FIG. It should be noted that FIG. 23 (and FIG. 24 described later) schematically illustrates a part of the configuration.

  The release valve 401A of FIG. 23 includes a hollow main body member 411, a tube connecting member 412 connected to a lower part thereof, and a cap member 413 closing an upper end opening of the main body member 411 as members constituting the casing 410. Have. Further, inside the main body member 411, a shaft member 425 movably arranged upward and downward is arranged. The shaft member 425 is provided with two seal members 428 and 429, and a part of the shaft member 425 is formed with a flange portion 425f.

  The shaft member 425 is urged upward by the coil spring S1 (FIG. 23), and in this state, the flange portion 425f presses against the seal member 429. In this state, fluid does not flow from the lower end opening 412a of the connection member 412 to the side opening 411a of the main body member 411 (or the reverse direction).

  On the other hand, when the end of the shaft member 425 protruding upward from the center of the cap member 413 is pressed, the flange portion 425f moves downward, so that the fluid flow path (not shown in detail) is opened, thereby The fluid can flow from the lower end opening 412a of the connection member 412 to the side opening 411a of the main body member 411 (or the opposite direction). In addition, regarding the flow path of the fluid, for example, a part of the flow path may be formed by a groove formed in the outer peripheral portion of the shaft member 425 along the longitudinal direction.

  As described above, in the chemical liquid circuit system according to the present invention, a release valve 401A as shown in FIG. 23 may be used.

  Alternatively, a release valve 401B as shown in FIG. 24 may be used. The release valve 401B of FIG. 24 has a hollow main body member 411 and a cap member 413 that closes an upper end opening thereof as members constituting the casing 410. Inside the main body member 411, a shaft member 425 arranged to be movable upward and downward is arranged. The shaft member 425 is provided with one seal member 429 and an O-ring R1. At an upper end of the shaft member 425 protruding upward from the cap member 413, a pressing member 416 having a flow path formed therein is attached. The pressing member 416 has a side opening 416a serving as a fluid inlet / outlet.

  Even in the release valve 401B configured as described above, when the shaft member 425 is not pressed, the flange portion 425f is pressed against the seal member 429 by the urging force of the coil spring S1, and as a result, the pressing member is pressed from the lower end opening 411a. The fluid does not flow toward the side opening 416a of the 416 (or the opposite direction). On the other hand, when the cap member shaft member 425 is pressed, a fluid flow path (details not shown) is opened, so that the fluid can flow.

(Other configurations)
As described above, an example of the present invention has been described with reference to the drawings. However, various conventionally known structures, devices, and devices can be applied to the circuit system of the present invention. For example, a structure called an octopus tube may be provided at any position in the circuit to prevent air bubbles from being injected into the patient. As an example, in the configuration of FIG. 1, an octopus tube may be provided between the connector 217 and the air sensor 232. The "octopus tube" is a protrusion (the outer shape may be any shape) like a head of an octopus with a hollow inside. It is for capturing. Therefore, it is preferable that the octopus tube is disposed so as to protrude vertically upward. Moreover, it is preferable to provide the circuit system in a place where the direction of the line (tube) is stable in the circuit system so that the posture does not change.

1. A medical liquid circuit kit used for angiography,
A contrast agent line connected to the contrast agent chamber;
A saline line connected to the saline chamber;
A syringe line connected to the syringe,
A patient line for delivering a contrast or saline solution to the patient,
A baseline portion to which each line is connected, wherein the contrast agent line and the physiological saline line are each connected in a T-shape,
And,
A first valve member disposed at a connection portion between the contrast agent line and the baseline portion, wherein (i) when a liquid is drawn toward an upstream side of the baseline portion, the contrast agent Flows from the line into the baseline portion, and (ii) when the liquid is pushed from the upstream side to the downstream side of the baseline portion, the liquid flows through the valve member in that direction. A first valve member configured to:
A second valve member disposed at a connection portion between the saline line and the baseline portion, wherein a liquid is pushed from an upstream side to a downstream side of the baseline portion or the saline A second valve member configured to flow liquid in that direction when pushed from the water line side toward the second valve member side;
A first release valve having a movable member and disposed on the saline line, wherein the release valve opens and closes the saline line by moving the movable member;
A liquid circuit kit for medical use, comprising:
2. The first release valve includes:
A liquid circuit kit, wherein the physiological saline is configured to flow toward the baseline section when the movable member is pressed from the outside.
3. further,
A transducer line having one end connected to the transducer and the other end connected to the baseline portion;
A second release valve having a movable member and disposed on the transducer line, wherein the second release valve opens and closes the line by moving the movable member;
A liquid circuit kit comprising:
4. An infusion chamber is provided in at least one of the contrast agent line and the saline line,
Liquid circuit kit.
5. A liquid circuit kit for medical use as described above,
An injector for detachably holding a syringe connected to the liquid circuit, and moving a piston member of the syringe to inject and suction liquid.
A switching device that holds a part of the liquid circuit and has a driving unit that moves the movable member of at least the first release valve;
A liquid circuit system comprising:
6. The liquid circuit system, wherein the drive unit of the switch has a drive source that operates in response to an external control signal.
7. A liquid circuit system, wherein the drive source is a motor.
8. The switching device further includes:
A liquid circuit system comprising an air sensor for detecting air bubbles in the patient line.

1 One-way valve 200 Liquid circuit system 201 Liquid circuit kit 202A, 202B Release valve 203 Movable member 205 Contrast agent line 206 Physiological saline line 207 Transducer line 208 Patient line 209 Line 210 Base line 213 Three-way cock 215A, 215B Dual check valve 215C 215D Connector 223 Physiological saline chamber 223S Sensor 226 Pump device 226a Syringe 227 Body 231 232 Air sensor 251 Syringe 260 Injector 270 Transducer 300 Switching device 301 Drive unit 332 Air sensor 401A, 401B Release valve 410 Casing 411 Body member 412 Tube connection member 413 Cap member 428, 429 Seal member 470 Roller pump 476 Roller 480 Piston pump 481, 486 Syringe V-1 to V-1 One-way valve S1 Coil spring

Claims (7)

A contrast agent line connected to the contrast agent chamber;
A saline line connected to the saline chamber;
A baseline unit to which the contrast agent line and the saline line are connected,
A patient line that is provided so as to extend from the baseline portion and sends a contrast agent and saline toward the patient;
One end is connected to the contrast medium line, and the contrast medium flows inside when the contrast medium in the contrast medium chamber is sucked into the contrast medium syringe and when the contrast medium in the contrast medium syringe is sent toward the patient. A contrast agent syringe line,
A medical liquid circuit capable of sending a contrast agent and a saline solution to a patient through the baseline section and the patient line,
The patient line is disposed at a position closer to the patient line than a junction between the contrast agent line and the baseline and a junction between the physiological saline line and the baseline. A one-way valve that allows flow to the line side but not the reverse,
A transducer line to which one end is connected to a position on the patient line side downstream of the one valve, and a transducer for monitoring a blood flow state of the patient is connected to the other end,
A liquid circuit for medical use comprising: further,
The liquid circuit according to claim 1, wherein an air sensor is provided at a position on the patient line side downstream of the one-way valve. The chemical liquid circuit according to claim 1 or 2,
A first piston drive mechanism for holding the contrast agent syringe and operating its piston member;
A second piston drive mechanism for holding the saline syringe and operating its piston member;
A chemical solution injection system comprising: further,
The drug solution injection system according to claim 3, further comprising a contrast agent chamber. further,
The drug solution injection system according to claim 3, further comprising a saline solution chamber. further,
The drug solution injection system according to any one of claims 3 to 5, further comprising a transducer. further,
The drug solution injection system according to any one of claims 3 to 6, further comprising an injection head provided with at least the first piston drive mechanism.

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