JP6353857B2 - Self-injection aid and self-injection system - Google Patents

Description

  The present invention relates to a self-injection aid used to assist self-injection that a patient himself injects, and a self-injection system comprising such a self-injection aid and a syringe filled with a therapeutic agent.

  Injections are generally performed by specialists who are medical professionals such as doctors and nurses. For example, in the case of chronic patients such as diabetes and rheumatism, the patient himself / herself is at a place other than a hospital such as home. In some cases, the drugs were self-injected. For example, in the case of advanced rheumatic patients, in order to relieve pain and suppress the progression of rheumatism, a treatment method is regularly carried out by self-injecting a therapeutic agent (adalimumab or etanercept) at home or the like.

  The syringe used for such self-injection generally includes an outer cylinder, an inner cylinder that is movable in the axial direction inside the outer cylinder, a collar attached to one end of the outer cylinder, and other outer cylinders. An injection needle provided at the end and a needle cap that covers the injection needle are provided.

  A syringe used for self-injection is packaged in a state filled with a therapeutic agent. The procedure for performing self-injection is as follows. That is, the syringe is first taken out from the package, the needle cap is removed from the syringe, the air bubbles contained in the therapeutic agent are removed, and then the therapeutic agent is injected.

  There was a strong sense of resistance for patients to make such self-injections. The reason for this is that there is a strong reliance on specialists who are medical professionals such as doctors and nurses to perform injections, and there is a fear that the patient himself will pierce the needle, and the injection itself Because there was a fear of

  In addition to the problem of such a patient's strong resistance to self-injection, for example, when a patient with advanced rheumatism performs self-injection, the fingers do not force their fingers due to pain or swelling or deformation, and There was a situation where it was difficult to pick a small object with the fingertip. Therefore, when a rheumatic patient self-injects, there existed a problem that the operation | movement which grasps a syringe, and the operation | movement which removes the needle cap of a syringe cannot be performed.

  As a self-injection aid that facilitates removal of the needle cap, for example, a device disclosed in Utility Model Registration No. 3143302 is known. The self-injection assisting device of the present invention includes an apparatus main body, and a main body cover that can be opened and closed with respect to the apparatus main body and is slidable in an axial direction between a syringe set position and an injectable position with respect to the apparatus main body. Prepare. When using this self-injection aid, the patient opens the main body cover and attaches the syringe to a predetermined position of the apparatus main body, closes the main body cover, and moves the main body cover from the syringe set position to the injectable position. The operation of sliding and removing the needle cap from the syringe, the operation of removing bubbles contained in the therapeutic agent filled in the syringe, and the operation of performing the injection are performed.

Utility Model Registration No. 3143302

  The above-described device requires three operations: an operation for mounting a syringe, an operation for closing the main body cover, and an operation for sliding the main body cover, which is difficult and troublesome for advanced rheumatic patients. It was. Furthermore, since the main body cover can be slid even when the main body cover is not securely closed, there is a problem that the main body cover opens during self-injection and the syringe falls from the apparatus main body. Further, since the main body cover is opaque, there is a problem that the syringe mounted on the apparatus main body cannot be confirmed when the main body cover is closed.

  Therefore, the present invention is easy to remove the needle cap from the syringe, the cover does not open during the self-injection and the syringe does not fall, relieves the patient's resistance to self-injection, An object of the present invention is to provide a self-injection assisting tool that can confirm a syringe in a closed state.

  In order to achieve the above object, the present invention provides a self-injection assisting device for assisting self-injection in which a patient himself injects a therapeutic agent filled in a syringe, wherein the syringe includes an outer tube and an inner tube. An inner cylinder movable in the axial direction, a collar attached to one end of the outer cylinder, an injection needle connected to a small diameter portion extending from the other end of the outer cylinder, and covering the injection needle and fitted into the small diameter portion A self-injection aid having a main body for fixing the syringe and a transparent cover that can be opened and closed with respect to the main body, the cover being fixed to the main body at a correct position. The self-injection assisting device can be further closed and locked with respect to the main body, further depending on the needle cap removal mechanism for removing the needle cap of the syringe and the closing operation of the cover relative to the main body, Operation to operate the needle cap removal mechanism Characterized in that it comprises a 構部.

  Further, according to the present invention, the operating mechanism portion includes a cam, the cover is provided to be rotatable with respect to the main body, the collar of the syringe has a recess, the main body has a protrusion, A protrusion is inserted into the depression at the base of the syringe to fix the syringe to the main body. The self-injection system of the present invention comprises the self-injection aid described above and a syringe filled with a therapeutic agent, and the therapeutic agent is a therapeutic agent for rheumatism.

  According to the self-injection assisting device of the present invention, since the operation mechanism operates the needle cap removal mechanism in accordance with the closing operation of the cover with respect to the main body, when the needle cap of the syringe is removed, the syringe is placed at the correct position of the main body. Only the operation of fixing the cover and the operation of closing the cover with respect to the main body are necessary, and this has the effect that it can be carried out with a simple operation compared to the prior art.

  Furthermore, according to the self-injection assisting device of the present invention, when the syringe is not fixed to the main body in the correct position, the cover cannot be closed, so that the needle cap is not removed, and it is safe. The effect is that self-injection can be performed. In addition, when the syringe is fixed to the main body at the correct position, the cover is closed and locked to the main body, and the cover does not open during self-injection and the syringe does not fall, so it is safe and reliable. The effect is that self-injection can be performed.

  Further, according to the present invention, the operation mechanism portion is provided with a cam, or the cover is provided so as to be rotatable with respect to the main body, or the collar of the syringe has a recess, and the main body has a protrusion. The protrusion is inserted into the depression of the collar of the syringe to fix the syringe to the main body, and can provide a reliable self-injection aid with a simple structure and at low cost. Have

  In addition, the self-injection system according to the present invention comprises the self-injection aid described above and a syringe filled with a therapeutic agent, and can perform self-injection with a simpler operation compared to the prior art. Is a therapeutic agent for rheumatism, and has an effect that even a patient with advanced rheumatism can easily inject itself.

  In addition, the length of the injection needle protruding outward from the self-injection aid of the present invention is shorter than the length of the injection needle itself, so that the patient's resistance to injection can be eased, and the cover is transparent, By checking the syringe fixed to the self-injection aid with the cover closed, it is possible to detect the self-injection operation error in advance, and the patient who self-injects the shape of the self-injection aid As an easy shape, even patients with advanced rheumatism can easily inject themselves, and the surface area that comes into contact with the patient is large, making it possible to perform stable self-injection in close contact with the injection site. Has an effect.

It is a perspective view of the self-injection assistance tool of this invention. It is a perspective view of a syringe. It is a disassembled perspective view of the self-injection assistance tool of this invention. It is a perspective view of a main body and a needle cap removal mechanism part when it sees from a downward direction. It is a figure explaining operation | movement of the operation | movement mechanism part which moves a needle cap removal mechanism part to the front according to closing operation | movement of the cover with respect to a main body. It is a perspective view which shows the self-injection assistance tool with which the cover is open with respect to the main body. It is a perspective view which shows the self-injection assistance tool with which the cover is opened, and a syringe. It is a perspective view which shows the self-injection assistance tool by which the syringe is fixed to the main body in the correct position, and the cover is opened. It is a perspective view which shows the state before rotating a cover with respect to a main body and the elastic part of a cover being inserted in the opening part of the bottom part of a main body. It is a perspective view which shows the state which rotated the cover to the closed position with respect to a main body, and the elastic part of the cover was inserted in the opening part of the bottom part of a main body. It is a perspective view which shows the state which stabbed the predetermined location of the patient with the injection needle using the self-injection aid of this invention. It is a perspective view which shows the state which pushed the inner cylinder of the syringe and injected the therapeutic agent.

  Hereinafter, the present invention will be described based on embodiments with reference to the drawings.

  FIG. 1 is a perspective view showing a self-injection assisting device 1 according to the present invention, in which a syringe 100 is fixed to a main body 10 of the self-injection assisting device 1 and a needle cap is removed. However, FIG. 1 does not show a spring that is a part of the operating mechanism. The patient holds the self-injection assisting tool 1 and inserts the injection needle 105 into a predetermined position of the patient to perform self-injection.

  In the following description, the direction of the end portion of the syringe 100 to which the injection needle 105 is attached is the front direction, the opposite direction is the rear direction, and similarly, the end portion of the self-injection assisting tool 1 from which the injection needle 105 protrudes. The direction is the forward direction, and the opposite direction is the backward direction.

  FIG. 2 is a perspective view of a syringe 100 used in the self-injection assisting device 1 of the present invention. The syringe 100 is a prefilled syringe prefilled with adalimumab, which is a therapeutic agent for rheumatism, for example, and includes an outer tube 101 filled with the therapeutic agent, an inner tube 102 that can move in the outer tube 101 in the axial direction, There is a gap 106 between the injection needle 105 connected to a small diameter portion 104 extending from the front end of the cylinder 101 and having an internal passage that fluidly communicates with the inside of the outer cylinder 101, and the front end of the outer cylinder 101. A needle cap 107 fitted to the small diameter portion 104 is provided, and a collar 103 is attached to the rear end of the outer cylinder 101.

  In addition, the outline external dimension of the syringe 100 is a state in which the inner cylinder 102 is pulled out from the outer cylinder 101 and the entire length is about 12 cm in the state shown in FIG. 2, and the inner cylinder 102 is completely pushed into the outer cylinder 101. The total length is about 9 cm. The collar 103 has a width of about 4.5 cm and a height of about 2.0 cm, and a recess (not shown) is formed from the bottom to the inside. The length of the needle cap 107 is about 2.7 cm, the length of the outer cylinder 101 is about 5.4 cm, the length of the small diameter portion 104 is about 1.0 cm, and the length of the injection needle 105 is The height is about 1.3 cm, and the gap 106 is about 0.1 cm. The outer diameter of the outer cylinder 101 is about 0.8 cm. The syringe 100 is formed of a suitable material such as a plastic material.

  FIG. 3 is an exploded perspective view of the self-injection aid 1 of the present invention. However, the orientation of the self-injection aid 1 shown in FIG. 3 is opposite to the orientation of the self-injection aid 1 shown in FIG. The self-injection assisting tool 1 includes a main body 10 for fixing the syringe 100, a transparent cover 30 that can be opened and closed with respect to the main body 10, and a needle cap for removing the needle cap 107 of the syringe 100 fixed to the main body 10. An extraction mechanism unit 50 and an operation mechanism unit 70 that operates the needle cap extraction mechanism unit 50 according to the closing operation of the cover 30 with respect to the main body 10 are provided. FIG. 3 also shows a spring 73 that is a part of the operation mechanism unit 70.

  FIG. 4 is a perspective view of the main body 10 and the needle cap removal mechanism 50 when viewed from below.

  The main body 10 is formed in the bottom portion 11, the rear portion 12, the side portion 13 and the front portion 14 that define a cavity for accommodating the needle cap removal mechanism portion 50 and the operation mechanism portion 70, and the collar 103 of the syringe 100. And a protrusion 15 to be inserted into the hollow. The rear portion 12 has a punched portion 16 that causes the inner cylinder 102 of the syringe 100 to protrude from the main body 10. Similarly, the front portion 14 has a punched-out portion 19 that causes the needle cap 107 of the syringe 100 to protrude from the main body 10. The side portion 13 receives the protrusion 72 of the cam 71 of the operation mechanism portion 70, receives the opening 17 that rotatably supports the cam 71, and the columnar protrusion 31 of the cover 30, and rotates the cover 30 freely. And the opening 20 into which the elastic part 32 of the cover 30 is inserted. Further, the side portion 13 includes an upward movement restriction member 21 that restricts upward movement of the needle cap removal mechanism portion 50 with respect to the main body 10. Further, as shown in FIG. 4, the bottom portion 11 restricts the vertical movement of the needle cap removal mechanism 50 with respect to the main body 10 and guides the movement of the needle cap removal mechanism 50 with respect to the main body 10 in the front-rear direction. Guide member 22 and a backward movement restriction member 23 for restricting backward movement of the needle cap removal mechanism 50 with respect to the main body 10. The main body 10 has a length in the front-rear direction of about 8 cm, a width of about 4.5 cm, and a height of about 2 cm.

  In addition, a plate-like member that increases the contact area with the patient is attached to the front surface 14 of the main body 10 that is a part that comes into contact with the patient who performs self-injection, and the self-injection is performed more closely to the place to be injected. Can do.

  The transparent cover 30 is accommodated in the columnar protrusion 31 fitted into the opening 18 of the side 13 of the main body 10 and the needle cap removal mechanism 50 when the cover 30 is in the closed position with respect to the main body 10. Protruding portions 33 and 34 for contacting and fixing the outer cylinder 101 of the syringe 100 received by the portion 53, and an elastic portion 32 inserted into the opening 20 provided in the side portion 13 of the main body 10. When the columnar protrusion 31 is fitted into the opening 18, the cover 30 is supported so as to be rotatable with respect to the main body 10. When the elastic part 32 of the cover 30 is inserted into the opening 20 of the main body 10, the cover 30 is locked with respect to the main body 10, and the cover 30 does not open from the main body 10 during the injection. The cover 30 can be opened by pushing the upper portion 35 of the elastic portion 32 from both sides to deform the elastic portion 32 inward and pulling out the elastic portion 32 from the opening 20.

  The outer dimensions of the cover 30 are about 6.5 cm in length, about 4.7 cm in width, and about 2 cm in height. Moreover, since the cover 30 is transparent, the syringe 100 fixed to the self-injection assisting tool 1 can be confirmed with the cover 30 closed, and an error in the operation of self-injection can be found in advance. .

  The needle cap removal mechanism part 50 is accommodated in the cavity of the main body 10 and supported so as to be slidable in the front-rear direction with respect to the main body 10. The needle cap removal mechanism 50 includes a claw 51 that fits into the gap 106 between the front end of the outer cylinder 101 of the syringe 100 and the needle cap 107, a pressing surface 52 that is pressed by the cam 71 of the operation mechanism 70, It has an accommodating portion 53 for receiving the outer cylinder 101 of the syringe 100 and a protruding portion 54 having a neck portion 55. A guide member 22 provided on the bottom 11 of the main body 10 engages with the neck 55 to restrict the vertical movement of the needle cap removal mechanism 50 with respect to the main body 10 and to move the needle cap removal mechanism 50 in the front-rear direction. To guide you. Further, the protrusion 55 of the needle cap removal mechanism 50 is in contact with the rearward movement restriction member 23 of the bottom 11 of the main body 10, so that the backward movement of the needle cap removal mechanism 50 with respect to the main body 10 is restricted. . The needle cap removal mechanism 50 is attached to the main body 10 in a rearward direction by a spring 73 provided between the front portion 14 of the main body 10 and the front surface 56 on which the claw portion 51 of the needle cap removal mechanism 50 is provided. Be forced.

  The operation mechanism unit 70 includes a cam 71 and a spring 73. The cam 71 has a protrusion 72 that is inserted into the opening 17 provided on the side portion 13 of the main body 10, and is supported rotatably with respect to the main body 10.

  FIG. 5 is a diagram illustrating the operation of the operation mechanism unit 70 that moves the needle cap removal mechanism unit 50 in the forward direction in accordance with the closing operation of the cover 30 with respect to the main body 10. As shown in the upper side of FIG. 5, in a state where the cover 30 is opened with respect to the main body 10, the cam 71 is disposed so as to protrude upward from the main body 10. As shown in the lower side of FIG. 5, according to the closing operation of the cover 30 with respect to the main body 10, the cover 30 pushes down and rotates the cam 71, and the cam 71 presses the pressing surface 52 of the needle cap removal mechanism 50. As a result, the urging force of the spring 73 is overcome and the needle cap removal mechanism 50 is moved forward. Since the claw 51 of the needle cap removal mechanism 50 is fitted in the gap 106, the claw 51 moves forward by the forward movement of the needle cap removal mechanism 50, and the needle cap 107 is removed from the syringe 100. To do. When the cover 30 is opened with respect to the main body 10, the spring 73 urges and moves the needle cap removal mechanism 50 with respect to the main body 10 and rotates the cam 71 in the opposite direction.

  Preferably, the body 10, the cover 30, the needle cap removal mechanism portion 50, and the cam 71 of the operation mechanism portion 70 of the self-injection assisting device 1 of the present invention are formed of an appropriate material such as plastic, and the spring 73 is appropriately It is made of a new metal.

  Hereinafter, with reference to FIGS. 6-12, the self-injection method using the self-injection assistance tool 1 of this invention is demonstrated. Note that the spring 73 is not shown in FIGS.

  FIG. 6 is a perspective view showing the self-injection assisting tool 1 with the cover 30 opened with respect to the main body 10, and FIG. 7 shows the self-injection assisting tool 1 with the cover 30 opened and the syringe 100. It is a perspective view shown.

  FIG. 8 is a perspective view showing the self-injection assisting tool 1 in which the syringe 100 is fixed to the main body 10 in a correct position and the cover 30 is opened. The protruding portion 15 of the main body 10 is inserted into a recess formed in the collar 103 of the syringe 100, the outer cylinder 101 of the syringe 100 is disposed in the housing portion 53 of the needle cap removal mechanism portion 50, and the needle cap of the syringe 100. 107 protrudes from the hollowed portion 19 of the main body 10, and the inner cylinder 102 of the syringe 100 protrudes from the hollowed portion 16 of the main body 10. Thus, the syringe 100 is arranged, and the claw portion 51 of the needle cap removal mechanism 50 is fitted into the gap 106.

  FIG. 9 is a perspective view showing a state before the cover 30 is rotated with respect to the main body 10 and the elastic portion 32 of the cover 30 is inserted into the opening 20 of the main body 10.

  FIG. 10 is a perspective view illustrating a state where the cover 30 is rotated to the closed position with respect to the main body 10 and the elastic portion 32 of the cover 30 is inserted into the opening 20 of the main body 10. The cam 71 of the operation mechanism unit 70 is completely pushed down and rotated by the cover 30 to press the pressing surface 52 of the needle cap removal mechanism unit 50 forward, and as a result, the claw unit 51 of the needle cap removal mechanism unit 50. However, the needle cap 107 of the syringe 100 is removed by moving forward. The patient then prepares for injection by removing air bubbles from the therapeutic agent filled in the syringe.

  The length of the injection needle 105 of the syringe 100 is about 1.3 cm. However, when the syringe 100 is fixed to the main body 10 and the cover 30 is closed, the injection needle 105 protruding from the self-injection assisting tool 1 is used. The length is about 0.6 to 0.7 cm, which is about half. Since the length of the injection needle 105 leads to fear of the patient, by using the self-injection aid 1 of the present invention, the patient's sense of resistance to injection can be eased. In addition, as shown in FIG. 10, the shape of the self-injection assisting tool 1 is a shape that is easy for a patient to grasp and realizes easy self-injection.

  FIG. 11 is a perspective view showing a state in which a predetermined portion of a patient is pierced with an injection needle 105 using the self-injection device 1 of the present invention. In FIG. 11, the patient's belly is stabbed with an injection needle 105.

  FIG. 12 is a perspective view illustrating a state in which the inner cylinder 102 of the syringe 100 is pushed and a therapeutic agent is injected. The patient holds the self-injection aid 1 with one hand and pushes the inner cylinder 102 of the syringe 100 with the other hand.

  After the injection, the self-injection aid 1 is removed from the patient. When the cover 30 is opened, the needle cap removal mechanism 50 is urged to a rearward position with respect to the main body 10 by the spring 73 and is moved backward until it comes into contact with the rearward movement restriction member 23 of the bottom 11 of the main body 10. Move to.

  The self-injection assisting device and self-injection system of the present invention can be suitably used in the field of technology for assisting self-injection injected by the patient himself, and in particular, the field of technology for rheumatic patients whose fingers are swollen or deformed. Can be suitably used.

DESCRIPTION OF SYMBOLS 1 Self-injection assistance tool 10 Main body 11 Bottom part 12 Rear part 13 Side part 14 Front part 15, 31, 54 Protrusion part 16, 19 Drilled part 17, 18, 20 Opening part 21 Upward movement restriction member 22 Guide member 23 Backward movement Restriction member 30 Cover 32 Elastic part 33, 34, 72 Projection part 35 Upper part 50 Needle cap removal mechanism part 51 Claw part 52 Pressing surface 53 Storage part 55 Neck part 70 Operation mechanism part 71 Cam 73 Spring 100 Syringe 101 Outer cylinder 102 Inner cylinder 103 collar 104 small diameter portion 105 injection needle 106 gap 107 needle cap

Claims (15)

A self-injection aid for injecting a therapeutic agent in a syringe,
A body having a bottom, a back, a side and a front defining a cavity;
A guide member arranged at the bottom;
A movable cap removal mechanism engaged in cooperation with the guide member;
A cover rotatably attached to the main body,
The movable cap removal mechanism is moved along the longitudinal axis and engaged with the movable cap removal mechanism and with the cover so as to move the needle cap away from the syringe barrel. A self-injection assisting device comprising an operating mechanism portion that can be combined.   The self-injection aid of claim 1, wherein the operating mechanism is configured to move the cap removal mechanism that is movable in response to the closing movement of the cover along the longitudinal axis. A movable cap removal mechanism
A receiving portion having an opening dimensioned to receive a syringe barrel;
The front,
A claw portion engaged in cooperation with the front portion;
A protrusion that is engageable with the guide member;
A pressing surface that can be engaged in cooperation by a part of the operating mechanism;
The self-injection assisting tool according to claim 1, further comprising a neck portion extending between the protruding portion and the accommodating portion. The operation mechanism is
A spring disposed between the front of the main body and the movable cap removal mechanism;
A cam engaged in cooperation with a movable cap removal mechanism;
The self-injection assisting device according to claim 1, further comprising a protrusion engaged in cooperation with the first opening in the side portion of the main body.   The self-injection aid of claim 1, wherein the front portion of the body includes an opening through which the needle cap of the syringe passes when the syringe is disposed in the body cavity. The cover is
A columnar protrusion engaged in cooperation with a second opening in the side of the body;
A syringe engaging protrusion that cooperates with a portion of the syringe when the cover is in a closed position relative to the body;
When the cover moves to the closed position, the cover includes an elastic portion that can be engaged with the third opening in the side of the main body, and when the elastic portion is pressed, the elastic portion is The self-injection aid of claim 1, comprising an upper portion configured to release.   The self-injection aid of claim 1, wherein the therapeutic agent comprises adalimumab or etanercept. The syringe
A tube containing a therapeutic agent having a first end and a second end and defining a longitudinal axis between the first end and the second end;
A shoulder adjacent to the first end;
A needle extending from the first end of the tube and in fluid communication with the tube;
A collar disposed adjacent to the second end of the tube;
A needle cap covering the needle and having an end disposed adjacent to the shoulder;
The self-injection assisting device according to claim 1, comprising a plunger movable inside the tube for releasing therapeutic agent through the needle.   The cover closure of claim 1 wherein the movable cap removal mechanism is moved along a longitudinal axis so that the closure of the cover cooperates with the movement mechanism to disengage the needle cap from the syringe barrel. Self-injection aids.   The self-injection assisting tool according to claim 1, further comprising a rearward restriction member disposed at a bottom portion of the main body so as to restrict a backward movement of the movable cap removal mechanism portion with respect to the main body. A movable cap removal mechanism,
A receiving portion having an opening dimensioned to receive a syringe barrel, the syringe barrel having a first end and a second end, and a first end and a second end The movable cap removal mechanism portion further defines a longitudinal axis between the portion and the movable cap removal mechanism portion;
A front portion having a claw portion that cooperates with a portion of a needle cap that covers a needle extending from a first end of the syringe barrel;
A protrusion having a neck, the neck extending between the receiving part and the protrusion, and the protrusion is movable with respect to the self-injection aid along the longitudinal axis. to guide the movement of, and engagement in cooperation with the guide member of self-injection aid, the movable cap removal mechanism further comprises
A movable cap removal mechanism comprising a pressing surface configured to contact the motion mechanism so as to move the movable cap removal mechanism.   The movable cap removal mechanism of claim 11, wherein the claw is configured to fit into a gap between the needle cap and a portion of the syringe.   The movable cap removal mechanism of claim 11, wherein the receptacle is configured to be received within a cavity of the self-injection aid.   12. The movable cap removal mechanism of claim 11, wherein the movable cap removal mechanism moves along the longitudinal axis to move the needle cap away from the syringe barrel. 12. The movable cap removal of claim 11 , wherein the operating mechanism is configured to move the movable cap removal mechanism along the longitudinal axis in response to movement of the cover of the self-injection aid. Mechanism part.

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