JP6068467B2 - Pharmaceutical container - Google Patents

Description

  The present invention relates to a pharmaceutical container.

  Conventionally, it has an outer cylinder, a chemical stored in the outer cylinder, a needle body provided in the outer cylinder, a gasket that can slide in the outer cylinder, and a pusher (plunger) that moves the gasket. Prefilled syringes are known. Such a prefilled syringe is configured to push the pusher and move the gasket to the distal end side, thereby injecting the drug solution from the needle body into the living body.

  Generally, the prefilled syringe is provided with a cap that protects the needle body (see, for example, Patent Document 1). The prefilled syringe described in Patent Document 1 has a cap (syringe needle cap) fixed to the outer cylinder. In order to make such a prefilled syringe usable, there is a problem that the operability deteriorates because it is necessary to remove the cap. In particular, such an operation of removing the cap can be performed without any problem as long as both hands move freely, but it is difficult for a person who has difficulty in hand, such as a rheumatic patient.

International Publication No. 2011/114917

  The objective of this invention is providing the pharmaceutical container which can be used without removing a cover body and is excellent in operativity.

Such an object is achieved by the present inventions (1) to (9) below.
(1) an outer cylinder having a cylindrical barrel portion provided with a space capable of being filled with a chemical solution, and a distal end portion provided on the distal end side of the barrel portion;
A needle body held at the tip of the outer cylinder;
A first cover that covers the needle body and is movable toward the proximal side with respect to the needle body;
A second cover provided on an outer periphery of the first cover and movable relative to the first cover relative to the first cover;
The first cover has a plug disposed opposite to the tip of the needle body,
The second cover is disposed opposite to the plug body on the distal end side of the plug body, communicates with the inside and outside of the second cover on the inside thereof, and allows the needle body to pass therethrough. Having a plug operation section having a space;
When the first cover moves toward the distal end side with respect to the second cover, the plug body is opened by the plug body operation portion, and the needle body passage space and the inside of the lid body communicate with each other. State
When the outer cylinder moves from the first state to the tip side with respect to the first cover, the needle body is configured to be in a second state in which the needle body is inserted into the needle body passage space. A pharmaceutical container characterized by

  (2) The pharmaceutical container according to (1), wherein movement of the outer cylinder toward the distal end side with respect to the first cover is restricted at least until the first state is reached.

  (3) The restriction of the movement of the outer cylinder to the front end side with respect to the first cover is performed after the first cover is further moved to the front end side with respect to the second cover after the first state is reached. The pharmaceutical container according to (2), which is released by moving.

(4) A cylindrical gripping portion fixed to the outer cylinder and provided so as to cover the outer periphery of the outer cylinder,
The first cover has an engaging portion that engages with an inner peripheral surface of the gripping portion, and the engagement restricts movement of the outer cylinder toward the tip side with respect to the first cover,
After the second cover is in the first state, the first cover is further moved toward the distal end side with respect to the second cover to act on the engaging portion, and The pharmaceutical container as described in said (3) which has the engagement cancellation | release part which cancels | releases a match.

(5) On the inner peripheral surface of the grip portion, a step surface facing the tip side is formed,
The engaging portion has a claw portion that engages with the step surface,
The pharmaceutical container according to (4), wherein the engagement between the stepped surface and the claw portion is released by the engagement release portion.

(6) Provided with a seal member provided on the outer periphery of the outer cylinder,
The internal space of the first cover is hermetically sealed by the plug, the seal member, and the outer cylinder,
The pharmaceutical container according to any one of (1) to (5), wherein the outer cylinder is slidable with respect to the first cover via the seal member.

(7) The outer cylinder includes an opening provided on a distal end side of the body portion, a sealing body that seals the opening, and a needle body holding portion that holds the needle body.
The needle body is a double-ended needle disposed opposite to the sealing body on the tip side from the sealing body,
The said needle body holding | maintenance part is a pharmaceutical container of any one of said (1) thru | or (6) currently hold | maintained at the said front-end | tip part so that a movement to a base end side is possible with respect to the said trunk | drum.

  (8) When the outer cylinder moves to the distal end side with respect to the second cover after entering the second state, the proximal end of the double-ended needle pierces the sealing body (7) The pharmaceutical container according to 1.

  (9) The pharmaceutical container according to any one of (1) to (8), wherein the space of the body portion is filled with the drug solution in advance.

  ADVANTAGE OF THE INVENTION According to this invention, it can be used without removing a cover body and the pharmaceutical container excellent in operativity can be provided. Specifically, according to the pharmaceutical container of the present invention, the needle body is protruded from the outer lid simply by moving the outer cylinder to the distal end side with respect to the inner lid with the inner lid attached, and punctures the living body. be able to. Therefore, it becomes a pharmaceutical container excellent in operability. Moreover, since the needle body can be punctured into the skin by one step of pressing the pharmaceutical container against the skin, it can be said that excellent operability can be exhibited from this point.

  In particular, until the first state is reached, the movement of the outer cylinder toward the distal end side with respect to the inner lid is restricted. For example, the needle body is damaged due to contact with an unopened plug body. Etc., and safety and operability are further improved.

FIG. 1 is a longitudinal sectional view showing a first embodiment of the pharmaceutical container of the present invention. FIG. 2 is a longitudinal sectional view of the pharmaceutical container shown in FIG. 1 rotated by 45 ° around the axis. FIG. 3 is a longitudinal sectional view of the pharmaceutical container shown in FIG. 1 rotated 90 ° around the axis. FIG. 4 is a longitudinal sectional view of the pharmaceutical container shown in FIG. 1 rotated 135 ° around the axis. FIG. 5 is a perspective view of a first cover and a second cover of the pharmaceutical container shown in FIG. 6 is a cross-sectional view for explaining the operation of the pharmaceutical container shown in FIG. FIG. 7 is a cross-sectional view for explaining the operation of the pharmaceutical container shown in FIG. FIG. 8 is a cross-sectional view for explaining the operation of the pharmaceutical container shown in FIG. FIG. 9 is a cross-sectional view for explaining the operation of the pharmaceutical container shown in FIG. FIG. 10 is a cross-sectional view for explaining the operation of the pharmaceutical container shown in FIG. FIG. 11 is a cross-sectional view for explaining the operation of the pharmaceutical container shown in FIG. FIG. 12 is a cross-sectional view for explaining the operation of the pharmaceutical container shown in FIG. FIG. 13 is a cross-sectional view of the pharmaceutical container according to the second embodiment of the present invention.

  Hereinafter, the pharmaceutical container of the present invention will be described in detail based on preferred embodiments shown in the accompanying drawings.

<First Embodiment>
First, a first embodiment of the pharmaceutical container of the present invention will be described.

  1 is a longitudinal sectional view showing a first embodiment of the pharmaceutical container of the present invention, FIG. 2 is a longitudinal sectional view of the pharmaceutical container shown in FIG. 1 rotated by 45 ° about an axis, and FIG. FIG. 4 is a longitudinal sectional view of the pharmaceutical container shown in FIG. 1 rotated by 135 ° around the axis, and FIG. 5 is a longitudinal sectional view of the pharmaceutical container shown in FIG. FIG. 6 to FIG. 12 are cross-sectional views for explaining the operation of the pharmaceutical container shown in FIG. Hereinafter, for convenience of explanation, the upper side in FIGS. 1 to 12 is referred to as a “base end” and the lower side is referred to as a “tip”. 1 to 4 show a state that is not yet used, and hereinafter, this state is also referred to as an “initial state (unused state)” for convenience of explanation.

  A syringe (medicine container) 10 shown in FIGS. 1 to 4 is a self-administered prefilled syringe in which a drug solution 100 is previously stored. Such a syringe 10 can be used for subcutaneous injection, for example. It can also be used for intramuscular injection or intradermal injection in which the drug solution 100 is administered between the epidermis and dermis.

  The syringe 10 includes a grip 1, an outer cylinder 2 provided in the grip 1, a double-ended needle (needle body) 4 held by the outer cylinder 2, and a gasket 5 that can slide in the outer cylinder 2. , A pusher 6 for moving the gasket 5, a first cover 7 for protecting the double-ended needle 4, a second cover 8 that is movable relative to the first cover 7 toward the proximal side, And a safety mechanism 9 for ensuring safety after use.

  In the syringe 10, a liquid chemical solution 100 is preliminarily filled in a space S that is surrounded by a body portion 21 of the outer cylinder 2 and a gasket 5, which will be described later, and is located on the distal end side of the gasket 5. The drug solution 100 is not particularly limited. For example, protein drugs such as antibodies, low molecular weight proteins, peptide drugs such as hormones, nucleic acid drugs, cell drugs, blood products, vaccines for preventing various infectious diseases, anticancer drugs, etc. Agents, anesthetics, narcotics, antibiotics, steroids, proteolytic enzyme inhibitors, sugar injection solutions such as heparin and glucose, electrolyte correction injection solutions such as sodium chloride and potassium lactate, vitamins, fat emulsions, contrast agents Etc.

  The volume of the chemical solution 100 stored in the syringe 10 varies depending on the type of the chemical solution 100, but is preferably 0.02 to 2 mL, for example, and more preferably 0.05 to 1.2 mL.

  Hereinafter, each part of the syringe 10 will be sequentially described in detail. In the following description, the positional relationship (engagement state) of each part in the initial state will be described.

-Outer cylinder-
The outer cylinder 2 includes a bottomed cylindrical barrel 21 that can be filled with the liquid chemical solution 100, a sealing body 23 that seals the opening (mouth) 213 on the distal end side of the barrel 21, and a sealing body 23. Is held by the distal end portion 27, a fixing portion 25 that secures the body portion 21, a cylindrical distal end portion 27 provided on the distal end side of the barrel portion 21, a flange 29 provided on the outer periphery of the proximal end of the barrel portion 21, and Needle body holding portion 3.

  The fixing portion 25 is located on the distal end side of the trunk portion 21 and is fixed to the trunk portion 21 by, for example, bonding, fitting, screwing, or the like. The sealing body 23 is fixed to the trunk portion 21 by being sandwiched between the fixing portion 25 and the trunk portion 21, and seals the opening 213. Further, an opening 251 coaxial with the opening 213 is formed in the fixed portion 25.

  The distal end portion 27 has a cylindrical shape, and is provided coaxially with the barrel portion 21 on the distal end side of the barrel portion 21. Further, the distal end portion 27 is provided so as to surround the periphery of the fixed portion 25. In other words, the fixing portion 25 is provided inside the tip portion 27.

  Four protrusions 271 projecting inward are formed on the inner peripheral surface of the tip portion 27 at equal intervals (approximately 90 ° intervals) along the circumferential direction. Further, a ring-shaped rib 273 that protrudes inward is formed on the inner peripheral surface of the distal end portion 27 and on the proximal end side of the protrusion 271. As will be described later, these protrusions 271 and ribs 273 have a function of engaging with the needle body holding portion 3 and preventing the needle body holding portion 3 from being detached from the distal end portion 27 and unnecessary (unintentional) displacement. doing.

  Further, the distal end portion 27 has a pair of flanges 275 and 277 that protrude from the outer peripheral surface and are spaced apart in the axial direction, and the seal member 50 is provided between the pair of flanges 275 and 277. The seal member 50 is provided in close contact with the inner peripheral surface of the first cover 7 (main body 71 described later) and is slidable. The seal member 50 is fixed to the outer periphery of the distal end portion 27 by a flange 275 and a flange 277.

  The constituent material of the outer cylinder 2 is not particularly limited, and examples thereof include cyclic polyolefins such as polyvinyl chloride, polyethylene, polypropylene, a cyclic olefin homopolymer (COP), and a cyclic olefin copolymer (COC). , Polystyrene, poly- (4-methylpentene-1), polycarbonate, acrylic resin, acrylonitrile-butadiene-styrene copolymer, polyethylene terephthalate, polyester such as polyethylene naphthalate, butadiene-styrene copolymer, polyamide (for example, Various resins such as Nylon 6, Nylon 6,6, Nylon 6,10, Nylon 12) are mentioned. Among them, polypropylene, cyclic polyolefin, polyester, poly- (4-methylpente Resins such as -1) is preferred.

  The needle body holding portion 3 is located on the distal end side of the body portion 21 and is held by the distal end portion 27. Further, the needle body holding portion 3 is movable in the axial direction with respect to the distal end portion 27. The needle body holding portion 3 has a bottomed cylindrical shape having a cylindrical side wall portion 31 and a bottom portion 33 that closes the distal end side opening of the side wall portion 31.

  Further, four long holes 311 extending in the axial direction are formed in the side wall portion 31 at equal intervals (approximately 90 ° intervals) along the circumferential direction. A projection 271 is inserted into each elongated hole 311. Therefore, the needle body holding part 3 is held by the tip part 27 in a state in which only movement in the axial direction is allowed with respect to the tip part 27.

  In the initial state, the protrusion 271 is in contact with the base end of the elongated hole 311, and the base end surface of the needle body holding portion 3 is in contact with the rib 273. Therefore, the needle body holding portion 3 is held by the distal end portion 27 in a state where movement in the axial direction with respect to the distal end portion 27 is restricted. When the distal end portion 27 is pressed toward the distal end side with a predetermined force or more against the needle body holding portion 3, the engagement between the proximal end surface of the needle body holding portion 3 and the rib 273 is released, and the proximal end with respect to the distal end portion 27 is released. The movement to the side is allowed.

  The constituent material of the needle body holding portion 3 is not particularly limited, and for example, the same material as the constituent material of the outer cylinder 2 described above can be used.

-Double-ended needle-
A double-ended needle (needle) 4 is held on the bottom 33 of the needle holder 3. That is, the double-ended needle 4 is indirectly held by the outer cylinder 2 via the needle body holding portion 3. Further, both ends of the double-ended needle 4 protrude from the bottom 33.

  The length of the double-ended needle 4 (the length of the portion protruding from the second cover 8 at the time of puncturing) is not particularly limited and varies depending on the purpose, but is 15 mm or less when used for subcutaneous injection as described later. It is preferable that the thickness is about 3 mm to 12.5 mm. Also, the outer diameter of the double-ended needle 4 is not particularly limited and varies depending on the purpose. However, when used for subcutaneous injection as described later, it is preferably 22 G or less on the basis of ISO medical needle tube, More preferably, it is 26G.

-Gasket-
A gasket 5 made of an elastic material is accommodated in the outer cylinder 2. By sliding the gasket 5 while being in close contact with the inner peripheral surface of the outer cylinder 2, the liquid-tightness can be more reliably maintained and the slidability can be improved.

  The material constituting the gasket 5 is not particularly limited, and various rubber materials such as natural rubber, butyl rubber, isoprene rubber, butadiene rubber, styrene-butadiene rubber, and silicone rubber, polyurethane, polyester, Examples thereof include various thermoplastic elastomers such as polyamide, olefin, and styrene, or elastic materials such as a mixture thereof. The same applies to the constituent material of the sealing member 50 described above.

-Pusher-
The pusher 6 has a main body portion 61 inserted into the outer cylinder 2 and a flange-like finger rest portion 63 provided at the base end of the main body portion 61. Further, the tip of the main body 61 is connected to the gasket 5. When a finger is put on the finger rest portion 63 and the pusher 6 is pushed toward the distal end side with respect to the outer cylinder 2, the gasket 5 moves in the outer cylinder 2 toward the distal end side. The chemical solution 100 is discharged from the tip.

  Further, the finger rest part 63 is provided with a pressing part 631 for pressing an arm part 95 (described later) of the safety mechanism 9 and elastically deforming it outward.

  The constituent material of the pusher 6 is not particularly limited, and for example, the same material as the constituent material of the outer cylinder 2 described above can be used.

  In addition, the pusher 6 does not need to be connected to the gasket 5 and may simply be in contact. Moreover, when the pusher 6 and the gasket 5 are not connected, the pusher 6 and the gasket 5 may be separated in the initial state.

-Grip part-
The grip portion 1 has a cylindrical shape and is disposed so as to surround the outer periphery of the outer tube 2. That is, the outer cylinder 2 is arranged inside the grip portion 1. Moreover, the holding part 1 and the outer cylinder 2 are provided coaxially. Such a gripping portion 1 is fixed to the outer cylinder 2 via a protrusion 291 protruding from the outer periphery of the flange 29. A space large enough to arrange a safety mechanism 9 to be described later is formed between the opening on the proximal end side of the grip portion 1 and the flange 29.

  In addition, the grip portion 1 includes a small diameter portion 13 having a predetermined inner diameter, and a large diameter portion 15 that is located on the distal end side of the small diameter portion 13 and has a larger inner diameter than the small diameter portion. Further, the proximal end and the distal end of the large-diameter portion 15 are configured by a surface substantially orthogonal to the axis of the syringe 10, and a step surface 17 facing the distal end side and a step surface 19 facing the proximal end side are formed. Yes. In the initial state, the first cover 7 is engaged with the step surfaces 17 and 19, respectively.

  The constituent material of the grip portion 1 is not particularly limited, and for example, the same material as the constituent material of the outer cylinder 2 described above can be used.

-First cover 7-
The first cover 7 is located on the distal end side of the outer cylinder 2 and the grip portion 1 and covers the double-ended needle 4. Thereby, damage to the double-ended needle 4 and erroneous puncture can be prevented. The first cover 7 can accommodate the double-ended needle 4 in an airtight manner. Thereby, contamination of the double-ended needle 4 can be prevented.

  1-4 and FIG. 5A, the first cover 7 has a bottomed cylindrical main body 71 and a plug 73 that seals the opening 715 on the distal end side of the main body 71. And a fixing portion 75 for fixing the plug 73 to the main body 71.

  The main body 71 has a cylindrical side wall portion 711 and a plate-like bottom portion 713 that closes the opening on the front end side of the side wall portion 711, and an opening 715 is formed at the center of the bottom portion 713. The fixing portion 75 is located on the distal end side of the main body 71 and is fixed to the main body 71 by engagement with a protrusion formed on the side wall portion 711. The plug 73 is fixed to the main body 71 by being sandwiched between the fixing portion 75 and the main body 71 and seals the opening 715. Further, an opening 751 coaxial with the opening 715 is formed in the fixed portion 75.

  The plug 73 has a slit 731 that crosses the openings 715 and 751. In the initial state, the slit 731 is hermetically closed. As described above, since the seal member 50 is slidably adhered to the inner peripheral surface of the main body 71, the space (internal space) S <b> 1 of the main body 71 is externally connected to the plug body 73, the seal member 50, and the outside in the initial state. The double-ended needle 4 which is hermetically sealed by the cylinder 2 and stored in the space S1 is prevented from being contaminated.

  In addition, the slit 731 of the plug 73 is inserted only partway from the distal end (base end) side, so that the slit 731 penetrates the plug 73 when a plug operation unit 83 described later comes into contact. Good. In this way, the airtightness of the space S <b> 1 can be more reliably maintained until the plug operation unit 83 contacts the plug 73.

  Such a plug 73 can be formed of, for example, an elastic body, and the constituent material thereof is not particularly limited. For example, the same material as the constituent material of the gasket 5 described above can be used.

  Four side walls 711 of the main body 71 are formed with four arm portions 717 extending from the middle toward the base end side at equal intervals (approximately 90 ° intervals) along the circumferential direction. In addition, a claw portion (engaging portion) 717 a that protrudes outward is formed at a base end portion that is a free end portion of each arm portion 717. A surface on the distal end side of each claw portion 717 a is an inclined surface inclined with respect to the axis of the syringe 10, and a surface on the proximal end side is an orthogonal surface orthogonal to the axis of the syringe 10.

  In the initial state, the base end side surface of each of the claw portions 717 a is in contact (engaged) with the stepped surface 17 of the grip portion 1. Therefore, in the initial state, the movement of the grip portion 1 toward the tip side with respect to the first cover 7 is restricted.

  Further, four holes 719 penetrating inside and outside are formed in the side wall portion 711 of the main body 71 at regular intervals (about 90 ° intervals) along the circumferential direction. Specifically, these four holes 719 are formed so that one hole 719 is positioned between a pair of adjacent arm portions 717. In addition, claw portions 871 (described later) of the second cover 8 are engaged with the edges on the front end side of these four holes 719.

  In addition, a projection 77 protruding to the outer periphery is formed on the side wall 711 of the main body 71. In the initial state, the protrusion 77 is located on the large diameter portion 15 and is in contact with the step surface 19. The contact between the projection 77 and the stepped surface 19 prevents the first cover 7 from being detached from the grip portion 1.

  The constituent material of the main body 71 and the fixing portion 75 is not particularly limited, and for example, the same material as the constituent material of the outer cylinder 2 described above can be used.

-Second cover 8-
The second cover 8 releases the engagement (engagement between the claw portions 717 a and the stepped surface 17) between the grip portion 1 and the first cover 7 described above, and the first cover with respect to the grip portion 1. 7 has a function to be movable to the base end side.

  As shown in FIGS. 1 to 4 and FIG. 5B, the second cover 8 has a bottomed cylindrical main body 81 disposed so as to cover the outer periphery of the first cover 7, and the main body 81. And a plug body operating portion 83 that acts on the plug body 73.

  The main body 81 has a cylindrical side wall portion 811, a plate-shaped bottom portion 813 that closes the opening on the front end side of the side wall portion 811, and an opening 815 formed at the center of the bottom portion 713. Further, the outer diameter of the main body 81 is equal to or slightly smaller than the inner diameter of the small diameter portion 13. The inner diameter of the main body 81 is equal to the outer diameter of the main body 71 but slightly larger. By setting it as such a size, the main body 81 can be moved (slid) with respect to the holding part 1 and the 1st cover 7 without wobbling.

  The main body 81 has four pressing portions 85 extending from the base end to the base end side of the side wall portion 811 at regular intervals (about 90 ° intervals) along the circumferential direction, and the side wall portion 811. Two arm portions 87 extending from the proximal end to the proximal end side are formed at equal intervals (approximately 180 ° intervals) along the circumferential direction. Each arm part 87 is located between a pair of adjacent pressing parts 85. The outer peripheral surfaces of the four pressing portions 85 and the two arm portions 87 are formed along the circumference of a circle concentric with the axis of the syringe 10, and the diameter of the circle is the small diameter portion 13 of the grip portion 1. Designed to be equal to or slightly smaller than the inner diameter of Thereby, at the time of operation of the syringe 10, each pressing portion 85 and each arm portion 87 can enter the inside of the small diameter portion 13.

  The shape of each pressing portion 85 and each arm portion 87 is not particularly limited as long as it can enter the inside of the small diameter portion 13.

  Each pressing portion 85 moves to the base end side with respect to the first cover 7, and presses the claw portion 717 a of the first cover 7 at the base end portion which is the free end portion, and elastically moves the arm portion 717 inward. By being deformed, it has a function as an engagement release portion for releasing the engagement between the claw portion 717a and the stepped surface 17. Each pressing portion 85 is disposed so as to overlap the corresponding claw portion 717a in the axial direction in order to perform the above function.

  On the other hand, a claw portion 871 protruding inward is formed at the base end portion which is a free end portion of each arm portion 87. The surface on the distal end side of each claw portion 871 is an orthogonal surface that is orthogonal to the axis of the syringe 10, and the surface on the proximal end side is an inclined surface that is inclined with respect to the axis of the syringe 10. In the initial state, the base end side surface of each claw portion 871 is engaged with the edge on the tip end side of the hole 719 formed in the first cover 7, and the second cover from the first cover 7 is engaged. 8 is prevented from being detached.

  Further, two slits 817 extending in the axial direction are formed in the side wall portion 811 at regular intervals (approximately 90 ° intervals) along the circumferential direction. Each slit 817 has a base end opened to the base end of the side wall portion 811, and a tip end extending to the tip end portion of the side wall portion 811. Further, each slit 817 is displaced by about 90 ° in the circumferential direction from the arm portion 87 and is positioned between a pair of adjacent pressing portions 85.

  Each slit 817 is engaged with the fixing portion 75 of the first cover 7 described above. Therefore, the main body 81 is only allowed to move in the axial direction with respect to the first cover 7, and other movements (for example, movement in the circumferential direction with respect to the first cover 7) are restricted.

  Further, the projection 77 of the first cover 7 is located between the pair of pressing portions 85 in which the slits 817 are located. The main body 81 is allowed only to move in the axial direction with respect to the first cover 7 by these engagements, and other movements are restricted. The width of the protrusion 77 (the length in the circumferential direction) is wider than the width of the slit 817 so that the protrusion 77 cannot enter the slit 817. Therefore, the movement of the second cover 8 toward the base end side with respect to the first cover 7 is stopped by the contact between the protrusion 77 and the base end of the main body 81.

  The plug operation unit 83 has a function of pressing the plug 73 from the base end side by moving the base end side relative to the first cover 7 to open the slit 731, and the needle body holding unit 3 with respect to the outer cylinder 2. And a function of pressing toward the base end side. Further, the double-ended needle 4 has a function of projecting from the tip of the second cover 8 through an internal space (needle passage space).

  Such a plug operation unit 83 has a cylindrical shape having openings at both ends, and is provided on the inner side of the main body 81 so as to extend from the end surface of the opening 815 (the surface on the base end side of the bottom portion 713) to the base end side. ing. The internal space of the plug operation unit 83 communicates with the opening 815.

  Moreover, the plug body operation part 83 has a through-hole 831 communicating with the inside and outside at the tip part. The through-hole 831 is a hole for releasing air in the space S1 when the syringe 10 is used (operated). The shape of the through hole 831 is not particularly limited, and may be a slit that opens to the base end surface of the plug operation unit 83, for example.

  The constituent material of the second cover 8 is not particularly limited, and for example, the same material as the constituent material of the outer cylinder 2 described above can be used.

-Safety mechanism-
After the administration of the drug solution 100 is completed, the safety mechanism 9 moves the first cover 7 to the distal end side, and again the state where the double-ended needle 4 is covered by the first cover 7 (the same state as the initial state) ).

  Such a safety mechanism 9 includes a pressing member 91 that presses the second cover 8 toward the distal end side, and a coil spring (biasing means) 99 that biases the pressing member 91 toward the distal end side.

  The pressing member 91 has a cylindrical main body 93 provided on the outer periphery of the outer cylinder 2 and two arm portions 95 extending from the main body 93 to the proximal end side.

  An annular rib 937 that protrudes inward is formed on the inner peripheral surface of the main body 93. The inner diameter of the rib 937 is equal to or slightly larger than the outer diameter of the body portion 21. By setting it as such an internal diameter, the press member 91 can be moved (slid) without wobbling with respect to the trunk | drum 21, and the operativity of the syringe 10 improves.

  In addition, four slits (notches) 931 that are open to the tip are formed at the tip of the main body 93 at equal intervals (approximately 90 ° apart) along the circumferential direction. Further, each slit 931 is provided to extend to the surface on the tip side of the rib 937. As will be described later, each of these slits 931 forms an escape portion for allowing elastic deformation to the outside due to the restoring force of the arm portion 717.

  The distal end portion of the main body 93 has a larger diameter than the base end portion, and the inner diameter and outer diameter thereof are substantially equal to the inner diameter and outer diameter of the main body 81.

  In addition, four grooves 933 that are connected to the slits 931 are formed on the outer peripheral surface of the main body 93. Each of these grooves 933 is a groove for forming a space in which each arm portion 717 can be inserted between the main body 93 and the grip portion 1 in order to release the arm portion 717 (claw portion 717a).

  Moreover, the outer peripheral surface 935 of the front-end | tip part of the main body 93 is comprised by the inclined surface. The outer peripheral surface 935 abuts on the proximal end surface of the claw portion 871 of the second cover 8 when the pressing member 91 moves to the distal end side, and elastically moves the arm portion 87 so as to spread the claw portion 871 outward. It has a function to deform.

  The two arm portions 95 are provided at equal intervals (about 180 °) along the circumferential direction of the main body 93. Each arm portion 95 is provided so as to be elastically deformable in the radial direction of the syringe 10. In addition, through holes 951 that pass through the inner and outer surfaces are formed in the base end portion that is the free end portion of each arm portion 95, and claws that protrude from the outer periphery of the flange 29 in these through holes 951 in the initial state. Part 293 is engaged. And the press member 91 is being fixed to the outer cylinder 2 by the said engagement. In addition, the inner peripheral surface 953 on the proximal end side of the arm portion 95 is an inclined surface. By setting the inner peripheral surface 953 to be an inclined surface, as will be described later, the inner peripheral surface 953 is pressed by the pusher 6 so that each arm portion 95 can be easily elastically deformed outward, and the claw portion 293 And the through hole 951 can be more reliably released.

  The constituent material of the pressing member 91 is not particularly limited, and for example, the same material as the constituent material of the outer cylinder 2 described above can be used.

The coil spring 99 is provided between the rib 29 protruding from the inner periphery of the main body 93 and the flange 29. The coil spring 99 is arranged in a contracted state in the initial state. As described above, since the main body 93 is fixed to the outer cylinder 2 in the initial state, the main body 93 does not move toward the distal end side with respect to the outer cylinder 2 even if the urging force of the coil spring 99 is received. When the engagement with the outer cylinder 2 is released by the operation, the coil spring 99 moves toward the distal end side with respect to the outer cylinder 2.
The syringe 10 of this embodiment has been described above.

  Next, an example of how to use the syringe 10 will be described with reference to FIGS. In addition, (a) of each figure shows the cross section corresponding to FIG. 2, (b) has shown the cross section corresponding to FIG. Moreover, although the usage method of the syringe 10 shown below is a method of using the syringe 10 for "subcutaneous injection", the usage method of the syringe 10 is not limited to this, For example, it is used for intradermal injection or intramuscular injection. You can also.

  First, the syringe 10 in an initial state (unused state) is prepared, and for example, the grasping portion 1 is grasped with one hand.

  Next, the first cover 7 (second cover 8) is pressed against the skin. Then, as shown in FIG. 6, the first cover 7 moves toward the distal end side with respect to the second cover 8 together with the grip portion 1. That is, the second cover 8 moves to the proximal end side relative to the first cover 7. By this movement, each claw portion 871 is pressed against the base end side edge of the hole 719, and the arm portion 87 is elastically deformed outward, and gets over the base end side edge of each claw portion 871 and the hole 719. Each claw portion 871 that has passed over the base end side edge of the hole 719 engages with the base end surface of the main body 71 of the first cover 7 that has further moved to the front end side.

  On the other hand, when the plug body 73 is pressed by the plug body operation section 83, the slit 731 that has been airtightly closed is expanded, and the plug body 73 is opened (becomes the first state). At this time, a force for moving the second cover 8 to the distal end side is generated by the restoring force of the plug 73, but as described above, each claw portion 871 is connected to the base end surface of the main body 71 of the first cover 7. Because of the engagement, such movement is prevented.

  When the first cover 7 is further pressed against the skin, the first cover 7 moves further to the distal side with respect to the second cover 8 together with the grip portion 1, that is, the second cover 8 moves to the first cover 7. As shown in FIG. 7, the claw portions 717a are pressed by the pressing portions 85 functioning as the disengagement portions, and the arm portions 717 are elastically deformed inward. . As a result, the engagement between the claw portion 717a and the stepped surface 17 is released, and the grip portion 1 can move toward the distal end side with respect to the first cover 7. At the same time, the fixing portion 75 comes into contact with the bottom portion 813, and the movement of the first cover 7 toward the distal end side with respect to the second cover 8 stops. On the other hand, when the plug body 73 moves further toward the distal end side with respect to the plug body operation section 83, the plug body operation section 83 enters the space S1 via the plug body 73.

  When the first cover 7 is further pressed against the skin, as shown in FIG. 8, the outer cylinder 2 and the needle body holding portion 3 maintain the relative positional relationship with each other and move toward the distal end side with respect to the first cover 7. Moving. As a result, the double-ended needle 4 is in the second state in which it is inserted into the internal space (needle passage space) of the plug operation section 83. When the first cover 7 is further pressed against the skin from the second state, the double-ended needle 4 is moved through the internal space (needle passage space) of the plug operation section 83 as shown in FIG. It protrudes from the front end surface of the cover 8 and is punctured by a living body. Then, when the needle body holding portion 3 comes into contact with the plug body operating portion 83, the movement of the needle body holding portion 3 is stopped and the tip side needle tip of the double-ended needle 4 reaches a predetermined depth in the living body.

  Here, in the syringe 10 of the present embodiment, the needle body is held by the engagement of the needle body holding portion 3 and the distal end portion 27 (the engagement between the base end surface of the needle body holding portion 3 and the rib 273 of the distal end portion 27). The relative positional relationship between the outer cylinder 2 and the needle body holding part 3 is maintained until the part 3 comes into contact with the plug body operating part 83. This prevents the sealing body 23 from being pierced by the proximal end needle tip of the double-ended needle 4 before the distal needle tip of the double-ended needle 4 reaches a predetermined depth in the living body. Can be prevented from leaking before puncturing.

  At this time, since each pressing portion 85, each arm portion 87, and each arm portion 717 penetrates into the small diameter portion 13, it is possible to prevent the grip portion 1 from being caught by the first cover 7 and the second cover 8. The In addition, the air in the space S1 passes through the through hole 831 (not shown in FIG. 8) of the plug body operation portion 83, between the first cover 7 and the disengagement member 8 (between the fixing portion 75 and the bottom portion 813). The gaps and the slits 731 (not shown in FIG. 8) escape to the outside, so that a smooth operation can be performed.

  When the first cover 7 is further pressed against the skin, as shown in FIG. 9, the engagement between the needle body holding portion 3 and the distal end portion 27 (the base end surface of the needle body holding portion 3 and the rib 273 of the distal end portion 27 are engaged. Engagement) is released, and the outer cylinder 2 moves toward the distal end side with respect to the needle body holding portion 3. The needle tip on the proximal end side of the double-ended needle 4 penetrates the sealing body 23 and reaches the space S.

  Next, as shown in FIG. 10, for example, when holding the grasping portion 1 and placing the thumb of the hand on the finger rest portion 63 and pushing the pusher 6 into the outer cylinder 2, the gasket 5 is moved to the distal end side. The medicinal solution 100 is injected into the skin from the tip of the double-ended needle 4. And the administration of the chemical | medical solution 100 is completed when the gasket 5 moves to the front end side with respect to the outer cylinder 2. FIG.

  Further, almost simultaneously with the completion of the movement of the gasket 5 toward the distal end side, the arm portions 95 of the pressing member 91 are pressed outward by the pressing portion 631 of the pusher 6, and the arm portions 95 are elastically deformed outward by the pressing. Then, the engagement between each arm portion 95 and the outer cylinder 2 (engagement between the through hole 951 and the claw portion 293) is released.

  When the engagement between each arm portion 95 and the outer cylinder 2 is released, the pressing member 91 moves toward the distal end side with respect to the outer cylinder 2 by the urging force of the coil spring 99. The moved pressing member 91 presses the second cover 8 toward the distal end side by bringing the outer peripheral surface 935 into contact with the base end side surface of each claw portion 871.

  Next, the syringe 10 is lifted from the skin in order to remove the double-ended needle 4. Then, the second cover 8 moves together with the pressing member 91 toward the front end side with respect to the first cover 7 by the pressing of the pressing member 91. At the time of this movement, each arm portion 87 tries to be elastically displaced outward by pressing by the pressing member 91, but the displacement is limited by colliding with the inner peripheral surface of the small diameter portion 13. Therefore, each claw part 871 is hooked on the base end surface of the main body 71, and the movement of the second cover 8 toward the distal end side with respect to the first cover 7 is stopped.

  On the other hand, the movement of the second cover 8 moves the free end of each pressing portion 85 to the distal end side with respect to the claw portion 717a. Therefore, the urging of the pressing portion 85 toward the inside of the arm portion 717 is released. Then, each arm 717 is deformed outward so as to return to the natural state. At this time, each arm 717 is deformed via a slit 931 formed in the pressing member 91. In this state, since each claw portion 717a is located at the small diameter portion 13, each arm portion 717 cannot return to the natural state and is slightly elastically deformed inward. In such a state, each arm portion 717 cannot escape into the groove 933 of the pressing member 91, and when the pressing member 91 moves toward the distal end side with respect to the first cover 7, as will be described later, the claw portion 717 a contacts the pressing member 91.

  The pressing of the second cover 8 by the pressing member 91 further continues, and the second cover 8 and the first cover 7 move toward the distal end side with respect to the grip portion 1 while maintaining the relative positional relationship. Then, as shown in FIG. 11, when each claw portion 871 reaches the large diameter portion 15, the restriction of the elastic deformation to the outside of each arm portion 87 described above is released, and each arm portion 87 is elastically deformed to the outside. To do. Due to the elastic deformation of each arm portion 87, the engagement between each claw portion 871 and the base end surface of the main body 71 is released, and the second cover 8 becomes movable to the front end side with respect to the first cover 7. .

  The pressing of the second cover 8 by the pressing member 91 further continues, and each claw portion 871 enters the hole 719 by the return of each arm portion 87 to the natural state, and the pressing member 91 comes into contact with each claw portion 717a. Therefore, both the first cover 7 and the second cover 8 are pressed by the pressing member 91.

  When the first cover 7 and the second cover 8 move to the distal end side while maintaining the relative positional relationship by the pressing of the pressing member 91, and each claw portion 717 a reaches the large diameter portion 15, each arm portion 717. Returns to the natural state, and each claw portion 717 a engages with the step surface 17. For this reason, the movement to the base end side with respect to the holding part 1 of the 1st cover 7 is prevented. Further, although not shown, the projection 77 abuts on the stepped surface 19 of the grip portion 1, and further movement of the first cover 7 toward the front end side with respect to the grip portion 1 is prevented.

  During such movement, the double-ended needle 4 is retracted into the first cover 7. That is, the double-ended needle 4 is covered with the first cover 7.

  When each claw portion 717a reaches the large diameter portion 15 and each claw portion 717a engages with the stepped surface 17, the contact between each claw portion 717a and the pressing member 91 (rib 937) as described above is released, The arm portion 717 can enter the groove 933 of the pressing member 91. Therefore, the pressing member 91 is again movable to the tip side with respect to the first cover 7.

Therefore, the pressing member 91 again presses only the second cover 8 toward the distal end side, and moves the second cover 8 toward the distal end side until each claw portion 871 contacts the distal end of the hole 719. Then, as shown in FIG. 12, the plug body operating portion 83 is pulled out from the plug body 73, and the plug body 73 is closed. Such movement may be performed by the restoring force of the plug 73, for example.
Thus, the use of the syringe 10 is completed.

  According to such a syringe 10, since the needle body (double-ended needle 4) can be punctured and the medicinal solution 100 can be administered without removing the first cover 7, excellent operability can be exhibited. . In particular, the first cover 7 is retracted, the double-ended needle 4 is punctured into the skin, and the double-ended needle 4 is inserted into the sealing body 23 by one step of grasping the grasping portion 1 and pressing the syringe 10 against the skin. Therefore, more excellent operability can be exhibited.

  Moreover, it can be used only by general operation as operation of a syringe which presses the syringe 10 against the skin, that is, since it can be used without requiring a special operation such as pressing a button, for example. Even if it sees from this point, the syringe 10 can exhibit the outstanding operativity.

  If the syringe 10 is not pressed, the first cover 7 is retracted and the double-ended needle 4 does not protrude, so that the state (initial state) in which the double-ended needle 4 is covered with the first cover 7 can be reliably maintained. . Therefore, the safety of the syringe 10 can be further increased. In addition, since the syringe 10 includes the safety mechanism 9, the double-ended needle 4 can be retracted into the first cover 7 after use. Therefore, erroneous puncture of the double-ended needle 4 can be prevented, and the safety of the syringe 10 can be further improved.

  Moreover, in the syringe 10, since the movement to the front end side with respect to the 1st cover 7 of the outer cylinder 2 is controlled until it will be in the state (1st state) of FIG. 6, the plug 73 which has not opened yet. And contact with the double-ended needle 4 can be avoided. As a result, it is possible to prevent the occurrence of coring in which the double-ended needle 4 scrapes off the plug body 73 and the peeling of the silicone applied to the double-ended needle 4 to reduce piercing resistance, which is excellent in safety and operability. Syringe 10 is obtained.

  Further, in the syringe 10, the first cover 7 is further pressed against the tip from the state of FIG. 6, and the first cover 7 is moved toward the tip with respect to the second cover 8, whereby the first of the outer cylinder 2. Since the restriction on the movement of the cover 7 toward the distal end side is released, the time when the first state is reached and the movement of the outer cylinder 2 toward the distal end side with respect to the first cover 7 become possible. A time difference can be generated from the time. Therefore, since the plug 73 can be reliably opened during the time difference, the safety and operability of the syringe 10 are further improved.

  Further, the syringe 10 has a grip portion 1 that surrounds the outer tube 2 and is fixed to the outer tube 2, and the grip portion 1 and the first cover 7 are engaged inside the grip portion 1. Therefore, the engaging portion can be hidden from the outside, in other words, it can be prevented from being touched by hand, and unintentional disengagement can be prevented. Therefore, the safety and operability of the syringe 10 are further improved.

Further, as shown in FIG. 8, the needle body holding portion 3 is restricted from moving toward the distal end side with respect to the second cover 8 by contact with the plug body operating portion 83, so that the outer side of the double-ended needle 4. The protrusion length to the can be easily and reliably controlled. Further, as described above, the plug body operating portion 83 abuts against the needle body holding portion 3 from the distal end side, so that both heads can be surely moved during the subsequent movement of the outer cylinder 2 relative to the needle body holding portion 3. The needle 4 can be pierced through the sealing body 23. The restriction of the movement of the needle body holding portion 3 to the distal end side with respect to the second cover 8 may be performed by contact with the base end surface (the inner surface on the distal end side) of the bottom portion 713 of the main body 71.
The syringe 10 according to the first embodiment has been described above.

  In such a first embodiment, the double-ended needle 4 protrudes from the distal end surface of the second cover 8, and after the distal end needle tip of the double-ended needle 4 has reached a predetermined depth in the living body, the sealing body 23 is moved to the double-ended head. The needle 4 is pierced by the proximal end of the needle 4 but before the double-ended needle 4 protrudes from the distal end surface of the second cover 8 or the distal end of the double-ended needle 4 has a predetermined depth in the living body. Before reaching, the sealing body 23 may be pierced by the proximal end needle tip of the double-ended needle 4. Specifically, for example, when the second state is reached, the skin enters the internal space (needle passage space) of the plug operation unit 83 and the tip of the double-ended needle 4 is pressed against the skin. The needle body holding part 3 may move to the proximal end side, and the proximal end needle tip of the double-ended needle 4 may be pierced by the sealing body 23. Further, before the tip end of the double-ended needle 4 protruding from the distal end surface of the second cover 8 reaches a predetermined depth in the living body, the double-ended needle 4 is pushed by the skin, and the needle body holding portion is at the proximal end. The proximal end needle tip of the double-ended needle 4 may be pierced by the sealing body 23.

Second Embodiment
Next, a second embodiment of the pharmaceutical container of the present invention will be described.

  FIG. 13 is a cross-sectional view of the pharmaceutical container according to the second embodiment of the present invention. FIG. 13 is a view showing a cross section corresponding to FIG. Further, in the following, for convenience of explanation, the upper side in FIG.

  Hereinafter, although the pharmaceutical container of this embodiment is demonstrated, it demonstrates centering around difference with the pharmaceutical container of 1st Embodiment, and abbreviate | omits the description about the same matter.

  The pharmaceutical container of this embodiment is the same as the pharmaceutical container of the first embodiment except that the configuration of the outer cylinder is different.

  As shown in FIG. 13, the syringe (pharmaceutical container) 10A of this embodiment includes a gripper 1, an outer cylinder 2A provided in the gripper 1, a needle body 4A provided in the outer cylinder 2A, an outer A gasket 5 that can slide in the cylinder 2, a pusher 6 that moves the gasket 5, a first cover 7 that protects the needle body 4A, and a second cover that allows the first cover 7 to move. It has a cover 8 and a safety mechanism 9 that ensures safety after use.

  The outer cylinder 2A includes a barrel portion 21A having a bottom portion 211A, a flange 29 provided on the outer periphery of the proximal end of the barrel portion 21A, and a seal member 50A provided on the outer periphery of the barrel portion 21A. Further, the bottom 211A of the outer cylinder 2A is formed with a tip 215A that protrudes toward the tip, and the needle 4A that connects the inside and outside of the space S is held by the tip 215A. That is, the needle body 4A is directly held by the outer cylinder 2A.

  The outer cylinder 2A has a pair of flanges 275A and 277A protruding from the outer peripheral surface and spaced apart in the axial direction, and a seal member 50A is provided between the pair of flanges 275A and 277A. The seal member 50A is slidably provided in close contact with the inner peripheral surface of the main body 71 of the first cover 7.

  The method of using such a syringe 10A is the step shown in FIG. 9 of the method of using the syringe 10 of the first embodiment described above, that is, the outer cylinder 2 moves to the distal end side with respect to the needle body holding portion 3, and both heads Except that there is no step where the proximal end of the needle 4 penetrates the sealing body 23 and reaches the space S, it is the same as the method of using the syringe 10 of the first embodiment described above.

  According to the second embodiment as described above, the same effects as those of the first embodiment described above can be obtained.

  As described above, the illustrated embodiment of the pharmaceutical container of the present invention has been described, but the present invention is not limited to this, and each part constituting the pharmaceutical container has an arbitrary configuration that can exhibit the same function. Can be substituted. Moreover, arbitrary components may be added. In addition, the pharmaceutical container of the present invention may be a combination of any two or more configurations (features) of the above embodiments.

  Further, in the above-described embodiment, the slit is formed in the plug body, and the slit is opened by the plug body operation unit. However, the configuration of this part is not limited to this. That is, for example, a slit is not formed in the plug body, and one plug body operation portion has a base end surface (surface on the plug body side) inclined with respect to an axis, like a blade surface (needle shape). The structure currently formed may be sufficient. In such a configuration, the plug body is configured to be opened when the plug body operation unit pierces the plug body. That is, “opening” the plug means that the slit is widened and includes that the plug is pierced.

  In the above-described embodiment, the configuration in which the seal member between the outer cylinder and the first cover is fixed to the outer cylinder has been described. However, the seal member is fixed to the inner peripheral surface of the first cover. The seal member and the outer peripheral surface of the outer cylinder may be slidably in close contact with each other.

  In the above-described embodiment, there is a time difference between the time when the first state is reached and the time when the outer cylinder can move toward the distal end side with respect to the first cover. A configuration in which the outer cylinder can be moved toward the distal end side with respect to the first cover at the same time may be employed. That is, at the same time that the plug body opens (becomes the first state), the pressing portion (engagement release portion) of the second cover releases the engagement between the grip portion and the first cover, and the outer cylinder You may be comprised so that the restriction | limiting of the movement to the front end side with respect to a 1st cover may be cancelled | released.

  In the above-described embodiment, the engagement between the grip portion and the first cover is released by the pressing portion that is the engagement release portion of the second cover. It may be omitted. In this case, the engagement between the gripping portion and the first cover is set so as to be able to be released by a force stronger than the force necessary for the plug body operating portion to open the plug body. Specifically, a protrusion that can be engaged with the stepped portion of the gripping portion from the distal end side is provided on the outer periphery on the proximal end side of the first cover. Then, the projection of the first cover gets over the stepped portion of the gripping portion toward the proximal end by a force stronger than the force required for the plug operating portion to open the plug, that is, the projection and the stepped portion The engagement of can be released. Accordingly, as in the above-described embodiment, a time difference can be generated between the time when the first state is reached and the time when the outer tube can be moved toward the tip side with respect to the first cover. It is possible to reliably prevent contact between the tip of the needle body held by the stopper and the stopper.

  In the above-described embodiment, the engagement between the grip portion and the first cover is released by the pressing portion that is the disengagement portion of the second cover. The engagement with the cover may not be released, and the grip portion may be configured to slide toward the tip with respect to the first cover. In this case, the sliding resistance between the gripping portion and the first cover is set to be stronger than the force required for the plug body operation section to open the plug body. Specifically, instead of engaging the stepped portion of the grip portion with the claw portion of the first cover, a protrusion is provided on the outer periphery on the proximal end side of the first cover, and this protrusion is connected to the inner peripheral surface of the grip portion. Engagement is slidable. The sliding resistance between the projection of the first cover and the inner peripheral surface of the gripping portion is set to be stronger than the force required for the plug body operating section to open the plug body. Accordingly, as in the above-described embodiment, a time difference can be generated between the time when the first state is reached and the time when the outer tube can be moved toward the tip side with respect to the first cover. It is possible to reliably prevent contact between the tip of the needle body held by the stopper and the stopper.

  In the above-described embodiment, the configuration in which the grip portion and the first cover are engaged has been described. However, the engagement between the grip portion and the first cover may be omitted. In this case, the sliding resistance between the seal member and the inner peripheral surface of the first cover or the outer peripheral surface of the outer cylinder is set to be stronger than the force required for the plug body operating portion to open the plug body. Accordingly, as in the above-described embodiment, a time difference can be generated between the time when the first state is reached and the time when the outer tube can be moved toward the tip side with respect to the first cover. It is possible to reliably prevent contact between the tip of the needle body held by the stopper and the stopper.

  In the above-described embodiment, the configuration with the seal member has been described. However, the seal member may be omitted, and the outer tube and the first cover may be engaged. In this case, the engagement between the outer cylinder and the first cover is set so as to be able to be released by a force stronger than the force required for the plug body operating portion to open the plug body. Specifically, providing the protrusion which fits the flange of the front-end | tip part of an outer cylinder in the internal peripheral surface of the main body of a 1st cover is mentioned. The projection of the main body is engaged with the flange of the tip portion from the tip side in an initial state, and the flange portion of the tip portion is pushed by a force stronger than the force required for the plug body operation portion to open the plug body. Get over the base side. In other words, the engagement between the protrusion and the flange can be released by a force stronger than the force required for the plug operation unit to open the plug. Accordingly, as in the above-described embodiment, a time difference can be generated between the time when the first state is reached and the time when the outer tube can be moved toward the tip side with respect to the first cover. It is possible to reliably prevent contact between the tip of the needle body held by the stopper and the stopper. The projection on the main body and the flange on the tip end are fitted over the entire circumference of the inner peripheral surface of the main body in the initial state, and with a force stronger than the force required for the plug body operating section to open the plug body. The configuration may be such that the fitting is released. Since the protrusion of the main body and the flange of the tip end portion are fitted over the entire circumference of the inner peripheral surface of the main body in the initial state, airtightness in the internal space of the main body can be ensured.

  Moreover, the structure which the flange of a front-end | tip part fits slidably with the internal peripheral surface of a main body instead of engagement with the protrusion of a main body and the flange of a front-end | tip part may be sufficient. In this case, the sliding resistance between the flange at the tip and the inner peripheral surface of the main body is set to be stronger than the force required for the plug body operating section to open the plug body. Accordingly, as in the above-described embodiment, a time difference can be generated between the time when the first state is reached and the time when the outer tube can be moved toward the tip side with respect to the first cover. It is possible to reliably prevent contact between the tip of the needle body held by the stopper and the stopper. Here, it is preferable that the flange of the front end part fitted with the inner peripheral surface of the main body is in contact with the inner peripheral surface of the main body over the entire circumference. Airtightness can be ensured.

The pharmaceutical container of the present invention includes a cylindrical barrel provided with a space capable of being filled with a chemical solution, an outer cylinder having a distal end provided on the distal end side of the barrel, and a distal end of the outer cylinder. A held needle body, a first cover that covers the needle body and is movable to the proximal end side with respect to the needle body, and is provided on an outer periphery of the first cover, with respect to the first cover A second cover that is relatively movable to the proximal end side, the first cover having a plug disposed opposite to the tip of the needle body, and the second cover includes A plug body operating portion that is disposed opposite to the plug body on the tip side of the plug body, communicates the inside and outside of the second cover inside thereof, and has a needle body passage space that allows the needle body to pass therethrough; And when the first cover moves to the tip side with respect to the second cover, the plug body is opened by the plug body operation unit, When the body passing space and the inside of the lid body are in a first state where the outer cylinder moves from the first state to the distal end side with respect to the first cover, the needle body is moved to the needle body. It is comprised so that it may be set as the 2nd state inserted in passage space. Therefore, it can be used without removing the lid, and a pharmaceutical container excellent in operability can be provided. Specifically, according to the pharmaceutical container of the present invention, the needle body is protruded from the outer lid simply by moving the outer cylinder to the distal end side with respect to the inner lid with the inner lid attached, and punctures the living body. be able to. Therefore, it becomes a pharmaceutical container excellent in operability. Moreover, since the needle body can be punctured into the skin by one step of pressing the pharmaceutical container against the skin, it can be said that excellent operability can be exhibited from this point.
Therefore, the pharmaceutical container of the present invention has industrial applicability.

DESCRIPTION OF SYMBOLS 1 Holding part 10 Syringe 10A Syringe 100 Chemical solution 13 Small diameter part 15 Large diameter part 17 Step surface 19 Step surface 2 Outer cylinder 2A Outer cylinder 21 Body part 21A Body part 211A Bottom part 213 Opening 215A Tip part 23 Sealing body 25 Fixing part 251 Opening 27 Tip portion 271 Protrusion 273 Rib 275 Flange 275A Flange 277 Flange 277A Flange 29 Flange 291 Protrusion 293 Claw 3 Needle body holding portion 31 Side wall portion 311 Long hole 33 Bottom portion 4 Double-headed needle 4A Needle body 5 Gasket 50 Seal member 50A Seal member 50A Pusher 61 Main body part 63 Finger pad part 631 Press part 7 First cover 71 Main body 711 Side wall part 713 Bottom part 715 Opening 717 Arm part 717a Claw part 719 Hole 73 Plug body 731 Slit 75 Fixing part 751 Opening 77 Protrusion 8 Second protrusion cover DESCRIPTION OF SYMBOLS 1 Main body 811 Side wall part 813 Bottom part 815 Opening 817 Slit 83 Plug body operation part 831 Through-hole 85 Press part 87 Arm part 871 Claw part 9 Safety mechanism 91 Press member 93 Main body 931 Slit 933 Groove 935 Outer surface 937 Rib 95 Arm part 951 Hole 953 Inner peripheral surface 99 Coil spring S space S1 space

Claims (9)

An outer cylinder having a cylindrical barrel provided with a space capable of being filled with a chemical solution, and a distal end provided on the distal end side of the barrel;
A needle body held at the tip of the outer cylinder;
A first cover that covers the needle body and is movable toward the proximal side with respect to the needle body;
A second cover provided on an outer periphery of the first cover and movable relative to the first cover relative to the first cover;
The first cover has a plug disposed opposite to the tip of the needle body,
The second cover is disposed opposite to the plug body on the distal end side of the plug body, communicates with the inside and outside of the second cover on the inside thereof, and allows the needle body to pass therethrough. Having a plug operation section having a space;
When the first cover moves toward the distal end side with respect to the second cover, the plug body is opened by the plug body operation portion, and the needle body passage space and the inside of the lid body communicate with each other. State
When the outer cylinder moves from the first state to the tip side with respect to the first cover, the needle body is configured to be in a second state in which the needle body is inserted into the needle body passage space. A pharmaceutical container characterized by   The pharmaceutical container according to claim 1, wherein movement of the outer cylinder toward the distal end side with respect to the first cover is restricted at least until the first state is reached.   The restriction of the movement of the outer cylinder to the tip side with respect to the first cover is that the first cover further moves to the tip side with respect to the second cover after the first state is reached. The pharmaceutical container according to claim 2, which is released by the above. A cylindrical gripping portion fixed to the outer cylinder and provided to cover the outer periphery of the outer cylinder;
The first cover has an engaging portion that engages with an inner peripheral surface of the gripping portion, and the engagement restricts movement of the outer cylinder toward the tip side with respect to the first cover,
After the second cover is in the first state, the first cover is further moved toward the distal end side with respect to the second cover to act on the engaging portion, and The pharmaceutical container according to claim 3, further comprising an engagement release portion for releasing the combination. On the inner peripheral surface of the grip portion, a step surface facing the tip side is formed,
The engaging portion has a claw portion that engages with the step surface,
The pharmaceutical container according to claim 4, wherein the disengagement part releases the engagement between the step surface and the claw part. A seal member provided on the outer periphery of the outer cylinder;
The internal space of the first cover is hermetically sealed by the plug, the seal member, and the outer cylinder,
The pharmaceutical container according to any one of claims 1 to 5, wherein the outer cylinder is slidable with respect to the first cover via the seal member. The outer cylinder has an opening provided on the distal end side of the body portion, a sealing body that seals the opening, and a needle body holding portion that holds the needle body,
The needle body is a double-ended needle disposed opposite to the sealing body on the tip side from the sealing body,
The pharmaceutical container according to any one of claims 1 to 6, wherein the needle body holding portion is held at the distal end portion so as to be movable toward a proximal end side with respect to the barrel portion.   The medicinal product according to claim 7, wherein the proximal end of the double-ended needle penetrates the sealing body when the outer cylinder moves to the distal end side with respect to the second cover after the second state is reached. container.   The pharmaceutical container according to any one of claims 1 to 8, wherein the space of the body portion is filled with the drug solution in advance.

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