JP5517119B2 - Cosmetics - Google Patents

Description

  The present invention relates to the production of melanin by ultraviolet light, comprising an olive fruit extract extracted from a ground product of frozen olive fruit cake, an olive fruit extract containing 1,3-butylene glycol and water. It has excellent effects to suppress and maintain a transparent skin (whitening), is excellent in preventing wrinkles and sagging, prevents dryness to prevent rough skin, maintains skin elasticity, and maintains moist and moist skin. It is related with the cosmetics which are excellent in an effect.

  Various cosmetics have been put on the market for the purpose of preventing or improving pigmentation caused by sunburn or aging, especially spots and freckles, and maintaining the skin in a youthful and healthy state. However, it is difficult to satisfactorily satisfy those purposes, and a new cosmetic material with improved such points is demanded.

  Olive is a plant belonging to the family Moleaceae that originates in the Mediterranean coast, and has been cultivated for food and oil extraction since ancient times. Olive fruit usually grows from around October and becomes pale green, and when it comes to purple-red spots, it is a suitable time for processing into green pickles. After that, around November, the whole becomes a so-called live olives with a purple-black color, which is suitable for salting processing. The ripe olive fruit around December contains about 15-30% oil, and olive oil is extracted from the olive fruit at this time. The olive fruit and olive oil thus obtained are known to have various excellent effects such as arteriosclerosis, gastric ulcer and constipation reduction, bone strengthening, prevention of aging, and skin beautification.

  Above all, olive oil is a vegetable oil containing various active ingredients such as oleic acid, provitamin A, vitamin B, vitamin Ks, polyphenols, etc., and has recently attracted attention for its health improvement effect. Has been reported to have a cancer-inhibiting effect based on phenotypes and polyphenols, and to promote bone formation based on provitamin A, vitamin D and vitamin K. Olive oil also has skin beautifying effects such as reducing rough skin, keeping the skin healthy, moisturizing the skin, protecting the skin, and preventing the skin from drying, and is formulated into cosmetics and topical medicines. ing.

  Moreover, as an olive fruit extract obtained from olive fruit, what is obtained by extracting the fruit and / or seed of an olive plant with water and / or an organic solvent is known (for example, refer patent document 1). This extract has been reported to have an action to remove active oxygen, an inhibitory effect on melanin production, and an inhibitory / killing effect on tumor cell growth, and the solvent used for the extraction provides safety to the human body of the resulting extract. However, from the viewpoint of increasing its action, it is desirable to use a mixed solvent of water and alcohol.

JP 2001-181197 A

  The present invention is excellent in the effect (whitening) of maintaining a transparent skin by suppressing the production of melanin by ultraviolet rays, excellent in preventing wrinkles and sagging, preventing dryness, preventing rough skin, and improving skin elasticity It is an object to provide a cosmetic that is excellent in the effect of maintaining and maintaining moist and moist skin.

  As a result of diligent research, the inventors of the present invention are an olive fruit extract containing an olive fruit extract extracted from a ground product of frozen olive fruit cake, 1,3-butylene glycol, and water, Cosmetics formulated with olive fruit extract containing specific polyphenols have excellent hyaluronidase activity inhibitory activity, elastase activity inhibitory activity, active oxygen scavenging action, collagen degradation inhibitory action, etc., especially excellent elastase activity inhibition Has the effect of suppressing the production of melanin by ultraviolet rays and is excellent in the effect of maintaining a transparent skin (whitening), excellent in preventing wrinkles and sagging, preventing dryness and preventing skin roughness, elasticity of skin It was found that it was excellent in the effect of maintaining moist and moist skin, and the present invention was completed.

That is, the present invention
(1) A cosmetic comprising an olive fruit extract extracted from a ground product of frozen olive fruit cake, an olive fruit extract containing 1,3-butylene glycol, and water. ,
The olive fruit extract contains tyrosol and hydroxytyrosol as polyphenols,
(2) The olive fruit extract also contains other polyphenols, and based on the total mass of polyphenols, the content of tyrosol is 1.5 to 3.5% by mass, and the content of hydroxytyrosol The cosmetic according to (1), wherein the amount is 0.1 to 1.0% by mass, and the content of oleuropein is less than 0.1% by mass,
(3) The cosmetic according to the above (2), wherein the olive fruit variety is Mission.
It is about.

The present invention will be described in more detail.
The olive fruit extract blended in the cosmetic composition of the present invention contains an olive fruit extract extracted from a ground product of frozen olive fruit cake, 1,3-butylene glycol, and water, and contains tyrosol. Is based on the total mass of polyphenols in the extract, 1.5 to 3.5 mass%, and the content of hydroxytyrosol is 0.1 to 1.0 mass based on the total mass of polyphenols in the extract %, And the content of oleuropein is less than 0.1% by weight based on the total weight of polyphenols in the extract. It is made by squeezing the fruit, subsequently freezing the resulting fruit koji and grinding the resulting frozen koji.
Examples of the olive fruit to be used include Mission, Manzanillo, Nevadillo Blanco, Picual, Ojiblanca, Arbequina, C, and Colnica. Gordal, Frantoio, Moroiolo, Recino, Coratina, Ascolana Terena, Olivel (Ol)
ivie), FS17 (Frantoistock 17), Lucca and the like.
A preferable olive fruit variety is, for example, Mission.
Freezing is preferably performed at a temperature of −10 ° C. or lower.
It is preferable to grind the frozen rice cake until the maximum length of the crushed pieces is 1 mm or less.
In addition, for the pulverization of the frozen koji, a normal pulverizer used in the food field can be used, but those that are not heated during pulverization are preferable, and a pulverizer that can be pulverized while cooling is used. preferable.

In the extraction operation, first, the olive fruit cake crushed after freezing is charged into an extraction container with a mixture of 1,3-butylene glycol as an extraction solvent and water.
The ground olive fruit cake can be used for the extraction operation in either a frozen state or a thawed state.

  As the extraction solvent, a 100% 1,3-butylene glycol solvent containing no other auxiliary solvent can be used. However, the extraction solvent may be a mixed solvent composed of water and 1,3-butylene glycol. When a mixed solvent is employed, the concentration is, for example, 30% by volume.

  Extraction is performed after charging the olive fruit koji and the extraction solvent into the extraction container. Extraction can be performed at a temperature slightly higher than room temperature in order to promote the extraction action. For example, when the extraction temperature is 50 to 60 ° C., the extraction time is about 5 hours.

  After the extraction is completed, the olive fruit cake and the extract are separated. Separation of olive fruit can be performed by filtration. If the obtained filtrate is convenient for the subsequent solid content separation, the total amount may be diluted several times.

  Next, filtration is performed again, and the solid content contained in the extract is further separated. Prior to solid content separation, it is preferable to adsorb and separate fine solids by adding an adsorbent such as diatomaceous earth to the liquid to be filtered. The amount of adsorbent added is not particularly limited, but is, for example, 10% by volume with respect to the liquid to be filtered.

  After separating the solid content in this way, the obtained filtrate is sterilized. Sterilization can be performed by ordinary heat sterilization. For example, pasteurization that is maintained at 80 to 90 ° C. for about 1 hour is preferable. High-temperature sterilization using a temperature exceeding 100 ° C. can shorten the sterilization time, but is not a preferable method because it causes decomposition of active ingredients contained in olive fruit straw.

By filtering the sterilized liquid again, an olive extract is obtained. This final filtration is preferably performed using a filter having a fine 0.5 μm cut-off, for example. By such filtration, the amount of solids contained in the olive extract can be reduced to 0.5% or less.
The olive extract contains tyrosol and hydroxytyrosol as polyphenols.
The olive extract also contains other polyphenols, and based on the total mass of the polyphenols, the content of tyrosol is 1.5 to 3.5% by mass, and the content of hydroxytyrosol is 0.1 to 1.0% by mass, and the content of oleuropein is less than 0.1% by mass.
An olive fruit extract is produced by diluting the olive extract obtained above as it is or as needed with 1,3-butylene glycol and water.

  The olive fruit extract of the present invention thus produced has excellent hyaluronidase activity inhibitory action, elastase activity inhibitory action, active oxygen scavenging action, collagen degradation inhibitory action, etc., and particularly excellent human leukocyte elastase inhibitory action. This function will be briefly described below.

-Human leukocyte elastase inhibitory action Elastin is an elastic tissue contained in the skin, and when it is decomposed, the skin gradually loses its tension and elasticity. Elastin is degraded by elastase, and elastase is activated by aging and by external and internal stimuli such as ultraviolet rays. Therefore, if the activity of elastase, which is a degrading enzyme of elastin, can be inhibited to suppress the degradation of elastin, the elasticity of the skin can be maintained and the skin can be kept firm and moist.
In addition, diseases caused by elastin degradation by elastase, collagen fiber degradation and / or abnormally increased proteoglycan degradation in humans, such as chronic obstructive pulmonary diseases such as emphysema, rheumatoid arthritis, atherosclerosis, adult respiratory distress It is also useful for the treatment and / or prevention of (ARDS), glomerulonephritis, myocardial infarction, ulcerative colitis, periodontal disease and the like.

  In addition, as described above, the olive fruit extract of the present invention has excellent hyaluronidase activity inhibiting action, active oxygen scavenging action, collagen degradation inhibiting action and the like.

Hyaluronidase activity inhibitory action Hyaluronic acid has functions such as moisture retention and flexibility maintenance, and is important for maintaining skin moisture. Hyaluronic acid is degraded by hyaluronidase, which is its hydrolase, but by inhibiting the activity of hyaluronidase, the degradation of hyaluronic acid can be suppressed and deterioration of the moisture retention, lubricity and flexibility of the skin can be prevented.

・ Reactive oxygen scavenging action Active oxygen is one of the external factors that cause inflammation and aging of the skin. It also damages body tissues and causes wrinkles. Therefore, elimination of active oxygen with an antioxidant or a radical scavenger is useful for preventing skin aging and inflammation. Whether or not the active oxygen scavenging action is exerted can be determined from the presence or absence of SOD-like activity and other antioxidant tests.

Collagen degradation inhibitory collagen Collagen is a substance that has an important role in maintaining skin tension and elasticity. However, when collagenase, which is a collagen-degrading enzyme, is activated by external stress such as ultraviolet rays or in vivo aging, the amount of collagen in the skin decreases, causing wrinkles and loosening. If the activity of collagenase can be inhibited, the degradation of collagen can be suppressed and the skin can be kept healthy.

And the cosmetics of this invention which mix | blend the olive fruit extract which has the above various outstanding effects are the effect (whitening) which suppresses the production | generation of the melanin by ultraviolet rays, and maintains a transparent skin. It is excellent in preventing wrinkles and sagging, preventing dryness to prevent rough skin, maintaining the elasticity of the skin, and maintaining the moist and moist skin.
Examples of the cosmetics of the present invention include basic cosmetics such as emulsions, creams, lotions, essences and packs, makeup cosmetics such as lipsticks, foundations, liquid foundations, makeup press powders, cheeks and white powders, facial cleansers, Examples include, but are not limited to, body shampoos, soaps and other cleaning cosmetics, and bath preparations.

  The compounding amount of the olive fruit extract in the cosmetics of the present invention is generally in the range of 1 to 50% by mass, preferably 2 to 20% by mass in the case of basic cosmetics, and generally 1 to 50 in the case of makeup cosmetics. In the case of cleaning cosmetics, it is generally in the range of 1 to 90% by weight, preferably in the range of 2 to 40% by weight.

In addition to the olive fruit extract obtained above, the cosmetics of the present invention include components usually used in cosmetics, such as oily ingredients, surfactants (synthetic and natural products), moisturizers, thickeners, An antiseptic / bactericidal agent, a powder component, an ultraviolet absorber, an antioxidant, a pigment, a fragrance and the like can be appropriately blended as necessary. Moreover, as long as the effectiveness and characteristics of the olive fruit extract obtained as described above are not impaired, other physiologically active ingredients may be combined in the cosmetic.

  Here, as the oil component, for example, olive oil, jojoba oil, castor oil, soybean oil, rice oil, rice germ oil, palm oil, palm oil, cacao oil, meadow foam oil, sheer butter, tea tree oil, avocado oil, Oils derived from plants such as macadamia nut oil and plant-derived squalane; Fats derived from animals such as mink oil and turtle oil; waxes such as beeswax, carnauba wax, rice wax, lanolin; liquid paraffin, petrolatum, paraffin wax, squalane, etc. Hydrocarbons; fatty acids such as myristic acid, palmitic acid, stearic acid, oleic acid, isostearic acid, cis-11-eicosenoic acid; higher alcohols such as lauryl alcohol, cetanol, stearyl alcohol; isopropyl myristate, palmitic acid Isopropyl, me Butyl phosphate, 2-ethylhexyl glycerides, higher fatty acid octyldodecyl (octyl stearate dodecyl and the like), and the synthetic esters and synthetic triglycerides such like.

Examples of the surfactant include polyoxyethylene alkyl ether, polyoxyethylene fatty acid ester, polyoxyethylene sorbitan fatty acid ester, glycerin fatty acid ester, polyglycerin fatty acid ester, polyoxyethylene glycerin fatty acid ester, polyoxyethylene hydrogenated castor oil, polyoxyethylene Nonionic surfactants such as oxyethylene sorbitol fatty acid esters; fatty acid salts, alkyl sulfates, alkylbenzene sulfonates, polyoxyethylene alkyl ether sulfates, polyoxyethylene fatty amine sulfates, polyoxyethylene alkyl phenyl ether sulfates, Polyoxyethylene alkyl ether phosphates, α-sulfonated fatty acid alkyl ester salts, polyoxyethylene alkyl phenyl ether phosphates, Quaternary ammonium salt, primary to tertiary fatty amine salt, trialkylbenzylammonium salt, alkylpyridinium salt, 2-alkyl-1-alkyl-1-hydroxyethylimidazolinium salt, N N, N-dimethyl-N-alkyl-N-carboxymethylammoniobetaine, N, N, N-trialkyl-N-, N, N-dimethyl-N-alkyl-N-carboxymethylammoniobetaine Amphoteric surfactants such as alkylene ammoniocarboxybetaine and N-acylamidopropyl-N ′, N′-dimethyl-N′-β-hydroxypropylammoniosulfobetaine can be used.
In addition, as emulsifiers or emulsifiers, stevia derivatives such as enzyme-treated stevia, lecithin and derivatives thereof, lactic acid bacteria fermented rice, lactic acid bacteria fermented rice, lactic acid bacteria fermented cereals (wheat, legumes, cereals, etc.), juzairo (Rhamnaceae zizyphus joazeiro) An extract or the like can also be blended.

  Examples of humectants include glycerin, propylene glycol, dipropylene glycol, 1,3-butylene glycol, polyethylene glycol, sorbitol, xylitol, sodium pyrrolidonecarboxylate, and sugars such as trehalose, lactic acid bacteria fermented rice, and mucopolysaccharides. (For example, hyaluronic acid and its derivatives, chondroitin and its derivatives, heparin and its derivatives, etc.), elastin and its derivatives, collagen and its derivatives, NMF related substances, lactic acid, urea, higher fatty acid octyldodecyl, seaweed extract, beech extract Products, seafood-derived collagen and derivatives thereof, various amino acids and derivatives thereof.

Examples of thickeners include, for example, brown algae such as alginic acid, agar, carrageenan, fucoidan, green algae or red algae-derived components, beech extract, pectin, locust bean gum, polysaccharides such as aloe polysaccharide, xanthan gum, tragacanth gum, guar gum, etc. Synthetic polymers such as gums, cellulose derivatives such as carboxymethylcellulose, hydroxyethylcellulose, polyvinyl alcohol, polyvinylpyrrolidone, carboxyvinyl polymer, acrylic acid / methacrylic acid copolymer; hyaluronic acid and its derivatives, polyglutamic acid and its derivatives, etc. Is mentioned.

  Examples of the antiseptic / bactericidal agent include urea; paraoxybenzoates such as methyl paraoxybenzoate, ethyl paraoxybenzoate, propyl paraoxybenzoate, and butyl paraoxybenzoate; phenoxyethanol, dichlorophene, hexachlorophene, chlorhexidine hydrochloride, benzaza chloride Luconium, salicylic acid, ethanol, undecylenic acid, phenols, jamal (imidazodenyl urea), 1,2-pentanediol, various essential oils, bark dry matter, and the like.

  Examples of powder components include sericite, titanium oxide, talc, kaolin, bentonite, zinc oxide, magnesium carbonate, magnesium oxide, zirconium oxide, barium sulfate, silicic anhydride, mica, nylon powder, polyethylene powder, silk powder, and cellulose. System powders, powders of cereals (rice, wheat, corn, millet, etc.), powders of beans (soybeans, red beans, etc.).

  Examples of the ultraviolet absorber include ethyl paraaminobenzoate, ethylhexyl paradimethylaminobenzoate, amyl salicylate and derivatives thereof, 2-ethylhexyl paramethoxycinnamate, octyl cinnamate, oxybenzone, 2,4-dihydroxybenzophenone, 2-hydroxy-4 -Methoxybenzophenone-5-sulfonate, 4-tertiarybutyl-4-methoxybenzoylmethane, 2- (2-hydroxy-5-methylphenyl) benzotriazole, urocanic acid, ethyl urocanate, aloe extract, etc. .

  Antioxidants include, for example, butylhydroxyanisole, butylhydroxytoluene, propyl gallate, vitamin E and its derivatives, beech extract, rice extract and the like.

Examples of physiologically active ingredients include whitening ingredients such as t-cycloamino acid derivatives, kojic acid and derivatives thereof, ascorbic acid and derivatives thereof, hydroquinone derivatives, ellagic acid and derivatives thereof, resorcinol derivatives, sucha akuhi extract, yukinoshita extract, rice bran Extract, rice bran extract hydrolyzate, lactic acid bacteria fermented rice, lactic acid bacteria fermented germinated rice, lactic acid bacteria fermented cereals (barley, beans, millet), white coconut hydrolyzed extract, murasakixikib extract, Pandanus amaririfolios (Pandanus amaryllifolius Roxb.) extract, Arcangelicia flava Merrilli extract, chamomile extract (trade name: chamomile ET), seaweed extract such as kombu, seaweed extract such as sea bream, linoleic acid and Derivatives or processed products thereof (eg liposomal linoleic acid), 2,5-dihydro Xylbenzoic acid derivatives and the like, and as skin aging preventing / beautifying components, animal or fish-derived collagen and derivatives thereof, elastin and derivatives thereof, nicotinic acid and derivatives thereof, glycyrrhizic acid and derivatives thereof (dipotassium salt, etc.), t -Cycloamino acid derivatives, vitamin A and derivatives thereof, vitamin E and derivatives thereof, allantoin, α-hydroxy acids, diisopropylamine dichloroacetate, γ-amino-β-hydroxybutyric acid, gentian extract, licorice extract, pearl extract, chamomile extract, Herbal extract such as cascon extract, perilla extract, carrot extract, aloe extract, rice extract hydrolyzate, rice bran extract hydrolyzate, rice fermentation extract, chlorella extract, brown algae extract, beetroot extract, anaaasa extract, amamo, etc. Seaweed drawing Things, mulberry bark extract, Juazeiro (Rhamnaceae zizyphus joazeiro) have extracts.

Examples of the kojic acid derivatives include kojic acid esters such as kojic acid monobutyrate, kojic acid monocaprate, kojic acid monopalmitate, kojic acid dibutyrate, kojic acid ethers, kojic acid sugar derivatives such as kojic acid glucoside, etc. However, as the ascorbic acid derivatives, for example, L-ascorbic acid-2-phosphate sodium, L-ascorbic acid-2-phosphate magnesium, L-ascorbic acid-2-sulfate sodium, L-ascorbic acid-2 -Ascorbic acid ester salts such as magnesium sulfate, L-ascorbic acid-2-glucoside (2-O-α-D-glucopyranosyl-L-ascorbic acid), L-ascorbic acid-5-glucoside (5-O-α) -D-glucopyranosyl-L-ascorbine Acid) ascorbic acid sugar derivatives, acylated 6-positions of these ascorbic acid sugar derivatives (acyl groups are hexanoyl, octanoyl, decanoyl, etc.), L-ascorbic acid tetraisopalmitate, L-ascorbic acid tetra L-ascorbic acid tetrafatty acid esters such as lauric acid ester, 3-O-ethylascorbic acid, L-ascorbic acid-2-phosphate-6-O-palmitate sodium and the like are hydroquinone derivatives such as arbutin (hydroquinone). -Β-D-glucopyranoside), α-arbutin (hydroquinone-α-D-glucopyranoside) and the like, and as resorcinol derivatives, for example, 4-n-butylresorcinol, 4-isoamylresorcinol and the like are 2,5-dihydroxybenzoic acid. Derivatives and For example, 2,5-diacetoxybenzoic acid, 2-acetoxy-5-hydroxybenzoic acid, 2-hydroxy-5-propionyloxybenzoic acid, etc., and nicotinic acid derivatives include, for example, nicotinic acid amide, nicotinic acid benzyl, etc. However, examples of the vitamin E derivative include vitamin E nicotinate and vitamin E linoleate, and examples of the α-hydroxy acid include lactic acid, malic acid, succinic acid, citric acid, and α-hydroxyoctanoic acid.

  The following examples illustrate the invention in more detail, but these examples are not intended to limit the invention to certain specific embodiments.

Production Examples 1 to 3: Production of olive fruit extract Olive fruit extract was produced as follows.
Preparation: Olive fruit 100 g after squeezing olive fruit of variety mission (Misson) was frozen in a freezer for food (−15 ° C.). The obtained olive frozen fruit cake was pulverized with a food pulverizer until the maximum length of the pulverized pieces became 1 mm or less. The obtained pulverized product and 1000 g of a 30% 1,3-butylene glycol aqueous solution were charged into an extraction container.
Extraction: The extraction vessel was heated to keep the interior at 50-60 ° C. Extraction was carried out with stirring at this temperature for 5 hours.
Olive fruit koji separation: After the completion of extraction, the olive fruit koji was removed and 1000 g of 30% 1,3-butylene glycol aqueous solution was added to dilute the extract twice.
Solid content separation: 200 g of diatomaceous earth (Radiolite # 200) was added to the diluted solution and stirred for 1 hour to adsorb fine solid matter. Thereafter, the diluted solution was filtered to separate solids and diatomaceous earth.
Sterilization: The filtrate was heated to 80 to 90 ° C. and sterilized by heating with stirring for 1 hour.
Final filtration: The sterilized filtrate was final filtered using a 0.45 μm cut-off filter.
According to the above procedure, 1541.2 g of olive fruit extract containing 0.38% solid content was obtained.
The same operation as described above was performed to produce a total of 3 lots of olive fruit extract.
A table summarizing the quantification results of the three lots produced is shown below.
The amount of polyphenol (total amount) was measured by the folin-thiocult method, and the amounts of oleuropein, hydroxytyrosol and tyrosol were determined by HPLC.

Test Example 1: Evaluation of Elastase Activity Inhibitory Action Except for using the 30% 1,3-butylene glycol aqueous solution instead of the olive fruit extract obtained in Example 1, the same process as in Example 1 was used. The elastase activity inhibitory action of the olive fruit water extract obtained in 1 was evaluated. The reason for using water for extraction is that elastase activity cannot be measured when the sample contains alcohol.
50 μL of olive fruit water extract, 25 μL of 12 μg / mL human leukocyte-derived elastase (ELASTIN PRODUCT CO. INC), and 25 μL of methoxy-succinyl-alanyl-alanyl-propylvaline-p-nitroanilide prepared to 8 mM, The reaction was carried out at 37 ° C. for 20 minutes. The solution after the reaction was measured for absorbance at 405 nm, and the produced nitroaniline was quantified.
As a result, 37.9% of human leukocyte elastase activity was inhibited.
The results obtained for the water extract are themselves good. However, it is known in the prior art that substances having elastase activity inhibitory ability are polysaccharides such as peptin, and polysaccharides are generally more efficient when using water and 1,3-butylene glycol than ethanol. It is also known that it can be extracted. Therefore, the olive fruit extract of Example 1 is expected to exhibit elastase activity that is much higher than that of the water extract tested in this test example, and much higher than that of the ethanol extract, which is much superior to that of the ethanol extract.

Example 1. Cream The following A component and B component were each heated to 80 ° C. or higher and then mixed by stirring. After this was cooled to 50 ° C., component C was added and further stirred and mixed to obtain a cream.
[Component A] Mass parts liquid paraffin 5.0
Glyceryl trioctanoate 4.0
Paraffin 5.0
Glyceryl monostearate 2.0
Polyoxyethylene (20) sorbitan monostearate 6.0
Butylparaben 0.1
[B component]
Olive fruit extract of Production Example 10.0
Glycerin 5.0
Carboxymethyl monostearate 0.1
NMF component 1.0
Purified water Amount of 100 parts [component C]
Perfume

Example 2 Emulsion The above A component and B component were each heated to 80 ° C. or higher and then mixed by stirring. After cooling this to 50 ° C., component C was added and further stirred and mixed to obtain an emulsion.
[Component A] Mass parts liquid paraffin 6.0
Glyceryl trioctanoate 4.0
Jojoba oil 1.0
Polyoxyethylene (20) sorbitan monostearate 2.0
Soy lecithin 1.5
Methylparaben 0.15
Ethylparaben 0.03
[B component]
Olive fruit extract of Production Example 10.0
Glycerin 3.0
1,3-butylene glycol 2.0
Carboxymethylcellulose 0.3
Sodium hyaluronate 0.01
Purified water Amount of 100 parts [component C]
Perfume

Example 3 Lotion A lotion was obtained by mixing the following ingredients.
[Components] Olive fruit extract 10.0 parts by mass of Production Example 1
Ethanol 10.0
Glycerin 3.0
1,3-butylene glycol 2.0
Methylparaben 0.2
Citric acid 0.1
Sodium citrate 0.3
Carboxyvinyl polymer 0.1
Fragrance Appropriate amount Potassium hydroxide Appropriate amount Purified water Amount that makes the total amount 100 parts

Example 4 Skin lotion The following A component and B component were each heated to 80 ° C. or higher, and then the B component was added to the A component and stirred, followed by homogenization with Hiscotron (5000 rpm) for 2 minutes.
After cooling this to 50 degreeC, C component was added and stirred and mixed, and also it cooled to 30 degrees C or less, and the lotion was obtained.
[Component A] Mass parts olive oil 1.0
Polyoxyethylene (5.5) cetyl alcohol 5.0
Butylparaben 0.1
[B component]
Olive fruit extract of production example 2 10.0
Ethanol 5.0
Glycerin 5.0
1,3-butylene glycol 5.0
Methylparaben 0.1
Potassium hydroxide appropriate amount Purified water Amount that makes the total amount 100 parts [component C]
Perfume

Example 5 FIG. Lotion Toner lotion was obtained by mixing the following ingredients.
[Ingredients] Olive fruit extract 50.0 parts by mass Production Example 1
Sodium hyaluronate 0.1
Brown algae extract 0.5
Aloe vera extract 0.5
Cuckoo extract 0.5
Chlorella extract 0.5
Perilla extract 0.5
Fragrance Appropriate amount of purified water Amount that makes 100 parts in total

Example 6 Emulsion The following A component and B component were each heated to 80 ° C. or higher and then mixed by stirring. After cooling this to 50 ° C., component C was added and further stirred and mixed to obtain an emulsion.
[Component A] Mass parts liquid paraffin 6.0
Glyceryl trioctanoate 4.0
Jojoba oil 1.0
Polyoxyethylene (20) sorbitan monosteare 2.0
Soy lecithin 1.5
Methylparaben 0.15
Ethylparaben 0.03
[B component]
Olive fruit extract of production example 2 10.0
L-ascorbic acid-2-glucoside 2.0
Potassium hydroxide 0.5
Glycerin 3.0
1,3-butylene glycol 2.0
Carboxymethylcellulose 0.3
Sodium hyaluronate 0.01
Purified water Amount of 100 parts [component C]
Perfume

Example 7 Liquid foundation The following A component and B component were heated and mixed and stirred. This was reheated, the following C component was added, poured into a mold, and stirred until it reached room temperature to obtain a liquid foundation.
[Component A] Mass parts stearic acid 2.4
Propylene glycol monostearate 2.0
Cetostearyl alcohol 0.2
Liquid lanolin 2.0
Liquid paraffin 3.0
Isopropyl myristate 8.5
Propylparaben 0.05
[B component]
Olive fruit extract of Production Example 3 10.0
Sodium carboxymethylcellulose 0.2
Bentonite 0.5
Propylene glycol 4.0
Triethanolamine 1.1
Methylparaben 0.1
Purified water Amount of 100 parts [component C]
Titanium oxide 8.0
Talc 4.0
Coloring pigment appropriate amount

Example 8 FIG. Cream foundation C component was mixed and pulverized with a pulverizer. The component B was mixed, and the pulverized component C was added thereto and uniformly dispersed in a colloid mill. The components A and B and C dispersed uniformly were each heated to 80 ° C., and then the components A were added to the components B and C while stirring, and further homogenized with Hiscotron (5000 rpm) for 2 minutes. After cooling this to 50 degreeC, D component was added and stirred and mixed, and also it cooled to 30 degrees C or less, stirring, and obtained the cream foundation. [Component A] Mass parts stearic acid 5.0
Cetanol 2.0
Glyceryl monostearate 3.0
Liquid paraffin 5.0
Squalane 3.0
Isopropyl myristate 8.0
Polyoxyethylene (20) glyceryl monostearate 2.0
Propylparaben 0.1
[B component]
Olive fruit extract of Production Example 3 10.0
Sorbitol 3.0
1,3-butylene glycol 5.0
Triethanolamine 1.5
Methylparaben 0.1
Purified water Amount of 100 parts [component C]
Titanium oxide 8.0
Talc 2.0
Kaolin 5.0
Bentonite 1.0
Coloring pigment appropriate amount [component D]
Fragrance 0.3

Example 9 Body Shampoo Each of the following A and B components was heated to 80 ° C. and dissolved uniformly, and then the B component was added to the A component, followed by stirring and cooling to room temperature to obtain a body shampoo.
[Component A] Mass parts N-lauroylmethylalanine sodium 25.0
Palm oil fatty acid potassium liquid (40%) 26.0
Palm oil fatty acid diethanolamide 3.0
Methylparaben 0.1
[B component]
Olive fruit extract of Production Example 3 10.0
1,3-butylene glycol 2.0
Amount of purified water totaling 100 parts

Example 10 Shampoo
The following components were heated and mixed uniformly to prepare a shampoo.
[Components] parts by mass N-coconut oil fatty acid glutamic acid triethanolamine 25.0
Lauric acid diethylethanolamide 5.0
Potassium myristate 5.0
Ethylene glycol distearate 2.0
Polyethylene glycol 400 15.0
Jojoba oil 1.0
Olive fruit extract 20.0 of Production Example 1
Chloroxylenol 0.1
Vitamin E 0.1
P-Hydroxybenzoate ester 0.2
Fragrance 0.3
Amount of purified water totaling 100 parts

Comparative Example Cream An olive fruit extract was obtained by performing the same operation as in Production Example 1 except that 100 g of frozen olive fruit was used instead of the pulverized product obtained by pulverizing 100 g of olive fruit cake after oil extraction. A cream was produced by replacing the olive fruit extract with the olive fruit extract of Production Example 1 in Example 1.

表２から明らかなように、比較例クリームに比べて、本発明のクリーム（化粧料）は、優れた皮膚美白効果を有することが認められ、これにより、オリーブ果実エキスを配合してなる本発明の化粧料は、紫外線によるメラニンの生成を抑制して透明感のある肌を維持する効果（美白）に優れることが示された。 Test Example 2: Whitening effect test About the cream of Example 1 and the comparative example cream, the degree of inhibition of pigmentation was confirmed by a monitor test.
〔Test method〕
The subjects were 15 healthy males and females aged 20 to 40 years, and the appropriate amount of each cosmetic was applied once every morning and evening for 4 weeks with the inner side of the left and right upper arms as the test section, and the state of pigmentation in the test section was as follows: The determination was made visually based on the determination criteria.
[Criteria]
Effective: A clear lightening effect was observed compared to the control example. Slightly effective: No effect where a lightening effect was observed compared to the control example: No effect: almost the same as the control example. Show.

As is apparent from Table 2, the cream (cosmetics) of the present invention was found to have an excellent skin whitening effect as compared with the comparative example cream, whereby the present invention formed by blending olive fruit extract. It was shown that the cosmetics of the present invention are excellent in the effect (whitening) of maintaining a transparent skin by suppressing the production of melanin by ultraviolet rays.

表３から明らかなように、比較例クリームに比べて、本発明のクリーム（化粧料）は、皮膚の老化或いは不健全化の典型的な症状であるシワ、たるみ等に対して優れた改善作用を示しており、しわ・たるみの防止に優れることが明らかとなった。また、比較例クリームに比べて、本発明のクリーム（化粧料）は、肌のはり、艶、潤いに対する改善効果に優れるものであり、乾燥を防いで肌荒れを防止し、肌の弾力性を保ち、しっとりと潤いある素肌を維持するものである。 Test Example 3: Improvement effect on fine wrinkles and improvement effect on skin skin, gloss and moisture The effect of the cream of Example 1 and the comparative example cream on the skin was examined by a monitor test.
[Test method]
Twenty randomly selected women aged 18 to 50 years were used as subjects, and the cream of Example 1 or the comparative example cream was allocated to each of the left and right cheeks. After being applied for 1 month (morning and evening) and for 1 month, the improvement effect on fine wrinkles and the improvement effect on skin tension, gloss and moisture were evaluated based on the following evaluation criteria.
[Evaluation criteria]
(Improvement effect on small wrinkles)
A: Almost inconspicuous B: Almost inconspicuous C: Slightly inconspicuous D: Unchanged E: On the contrary (increased effect on skin tension, gloss, moisture)
A: Clearly improved B: Significantly improved C: Slightly improved D: Unchanged E: On the contrary, it got worse [Result]
The results are shown in Table 3. In addition, the number of each evaluation column of AE in a table | surface shows the number of the test subjects who performed the said evaluation in 20 test subjects.

As is apparent from Table 3, the cream (cosmetics) of the present invention has an excellent improving effect on wrinkles, sagging and the like, which are typical symptoms of aging or unhealthy skin, as compared with the comparative cream. It was revealed that it is excellent in preventing wrinkles and sagging. Compared to the comparative cream, the cream (cosmetics) of the present invention is superior in improving the skin's elasticity, gloss and moisture, prevents dryness and prevents rough skin, and maintains skin elasticity. Maintains moist and moist skin.

According to the present invention, it suppresses the generation of melanin by ultraviolet rays and is excellent in the effect of maintaining a transparent skin (whitening), is excellent in preventing wrinkles and sagging, prevents dryness and prevents rough skin, and improves skin elasticity A cosmetic that is excellent in the effect of maintaining and maintaining moist and moist skin is provided.
As a result, it suppresses the generation of melanin by UV rays and is effective in maintaining a transparent skin (whitening), prevents wrinkles and sagging, prevents dryness, prevents rough skin, and maintains skin elasticity. Basic cosmetics such as milky lotion, cream, lotion, essence, and pack, makeup cosmetics such as lipstick, foundation, liquid foundation, makeup press powder, blusher, white powder, etc. that are excellent in maintaining moist and moist skin. , Cleansing cosmetics such as facial cleansers, body shampoos, soaps, and bath preparations.

Claims (1)

A cosmetic comprising an olive fruit extract extracted from a ground product of frozen olive fruit cake, an olive fruit extract containing 1,3-butylene glycol and water,
The olive fruit variety is Misson, and the olive fruit extract contains, as polyphenols, tyrosol , hydroxytyrosol and other polyphenols, and the content of tyrosol based on the total mass of polyphenols, respectively. Is 1.5 to 3.5% by mass, the content of hydroxytyrosol is 0.1 to 1.0% by mass, and the content of oleuropein is less than 0.1% by mass And cosmetics.