JP4568487B2 - Growth promoting agent for nasal administration of livestock and method for raising livestock - Google Patents
Growth promoting agent for nasal administration of livestock and method for raising livestock Download PDFInfo
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- JP4568487B2 JP4568487B2 JP2003293271A JP2003293271A JP4568487B2 JP 4568487 B2 JP4568487 B2 JP 4568487B2 JP 2003293271 A JP2003293271 A JP 2003293271A JP 2003293271 A JP2003293271 A JP 2003293271A JP 4568487 B2 JP4568487 B2 JP 4568487B2
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- livestock
- promoting agent
- nasal administration
- growth promoting
- pigs
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- 238000000034 method Methods 0.000 title claims description 6
- 230000001737 promoting effect Effects 0.000 title description 11
- 244000144972 livestock Species 0.000 title description 8
- 239000003795 chemical substances by application Substances 0.000 claims description 12
- 210000003928 nasal cavity Anatomy 0.000 claims description 11
- 241000282887 Suidae Species 0.000 claims description 8
- 239000000284 extract Substances 0.000 claims description 7
- 239000007788 liquid Substances 0.000 claims description 5
- 235000003092 Artemisia dracunculus Nutrition 0.000 claims description 3
- 240000001851 Artemisia dracunculus Species 0.000 claims description 3
- 244000223760 Cinnamomum zeylanicum Species 0.000 claims description 3
- 235000007129 Cuminum cyminum Nutrition 0.000 claims description 3
- 244000304337 Cuminum cyminum Species 0.000 claims description 3
- 240000004784 Cymbopogon citratus Species 0.000 claims description 3
- 235000017897 Cymbopogon citratus Nutrition 0.000 claims description 3
- 235000013628 Lantana involucrata Nutrition 0.000 claims description 3
- 235000006677 Monarda citriodora ssp. austromontana Nutrition 0.000 claims description 3
- 240000007673 Origanum vulgare Species 0.000 claims description 3
- 235000006990 Pimenta dioica Nutrition 0.000 claims description 3
- 240000008474 Pimenta dioica Species 0.000 claims description 3
- 244000178231 Rosmarinus officinalis Species 0.000 claims description 3
- 235000016639 Syzygium aromaticum Nutrition 0.000 claims description 3
- 244000223014 Syzygium aromaticum Species 0.000 claims description 3
- 235000007303 Thymus vulgaris Nutrition 0.000 claims description 3
- 240000002657 Thymus vulgaris Species 0.000 claims description 3
- 235000017803 cinnamon Nutrition 0.000 claims description 3
- 239000010330 ougon Substances 0.000 claims description 3
- 239000007921 spray Substances 0.000 claims description 3
- 239000001585 thymus vulgaris Substances 0.000 claims description 3
- 239000004480 active ingredient Substances 0.000 claims description 2
- 235000008216 herbs Nutrition 0.000 description 7
- 241000282898 Sus scrofa Species 0.000 description 5
- 239000007952 growth promoter Substances 0.000 description 5
- 239000003814 drug Substances 0.000 description 4
- 239000004677 Nylon Substances 0.000 description 3
- 229920001778 nylon Polymers 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 239000003242 anti bacterial agent Substances 0.000 description 2
- 229940088710 antibiotic agent Drugs 0.000 description 2
- 238000009395 breeding Methods 0.000 description 2
- 230000001488 breeding effect Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 235000013372 meat Nutrition 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 230000003449 preventive effect Effects 0.000 description 2
- 239000008399 tap water Substances 0.000 description 2
- 235000020679 tap water Nutrition 0.000 description 2
- 229940124597 therapeutic agent Drugs 0.000 description 2
- 241001116389 Aloe Species 0.000 description 1
- 241000272517 Anseriformes Species 0.000 description 1
- 241000283690 Bos taurus Species 0.000 description 1
- 241000283707 Capra Species 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- 239000004129 EU approved improving agent Substances 0.000 description 1
- 241000283086 Equidae Species 0.000 description 1
- 241000282326 Felis catus Species 0.000 description 1
- 241000287828 Gallus gallus Species 0.000 description 1
- 235000001453 Glycyrrhiza echinata Nutrition 0.000 description 1
- 244000303040 Glycyrrhiza glabra Species 0.000 description 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 description 1
- 235000017382 Glycyrrhiza lepidota Nutrition 0.000 description 1
- 241001494479 Pecora Species 0.000 description 1
- 241000286209 Phasianidae Species 0.000 description 1
- 241000271567 Struthioniformes Species 0.000 description 1
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 description 1
- 235000011399 aloe vera Nutrition 0.000 description 1
- 235000013330 chicken meat Nutrition 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 210000003298 dental enamel Anatomy 0.000 description 1
- 238000004821 distillation Methods 0.000 description 1
- 235000019441 ethanol Nutrition 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000012676 herbal extract Substances 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 229940010454 licorice Drugs 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000004584 weight gain Effects 0.000 description 1
- 235000019786 weight gain Nutrition 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Description
本発明は、家畜の鼻腔投与用発育促進剤およびその鼻腔投与用発育促進剤を用いた家畜の飼育方法に関する。 The present invention relates to a growth promoting agent for nasal administration of livestock and a method for raising livestock using the growth promoting agent for nasal administration.
従来家畜の疾病に対し、抗生物質等の薬剤が多く用いられていた。しかしながら抗生物質を連用すると薬剤耐性が生じる欠点があった。その他の薬剤を投与した場合にも出荷前に休薬期間を設けなければならず、その間における予防的な治療が行えない欠点があった。そこで近年はハーブ類が各種疾病の治療剤あるいは予防剤として用いられるようになった（特許文献１参照）。またハーブ類を家畜に給餌して肉質を改善する方法も提案されている（特許文献２参照）。
しかしながら、これらはいずれも経口投与あるいは経口給餌の方法が採られ投与量も比較的多かった。
However, all of these methods were administered orally or fed, and the doses were relatively high.
本発明者等は、治療剤や肉質改善剤として知られているハーブ類の他の用途について種々研究を重ねた結果意外にも少量のハーブ抽出液を家畜の鼻腔に投与することにより、著しく発育が促進されることを見出し本発明を完成するに至った。 As a result of extensive research on other uses of herbs known as therapeutic agents and meat quality improving agents, the present inventors have surprisingly developed significantly by administering a small amount of herbal extract into the nasal cavity of domestic animals. As a result, the present invention was completed.
すなわち、本発明は、クローブ、オレガノ、タイム、オールスパイス、ローズマリー、シナモン、タラゴン、レモングラス、クミン及びオウゴンから選ばれる少なくとも１種のハーブ抽出物を有効成分とし、液体として豚の鼻腔内に噴霧あるいは豚の鼻腔内に点滴投与される豚の発育促進剤およびその発育促進剤を液体として豚の鼻腔内に噴霧あるいは豚の鼻腔内に点滴投与する豚の飼育方法である。 That is, the present invention comprises at least one herb extract selected from clove, oregano, thyme, allspice, rosemary, cinnamon, tarragon, lemongrass, cumin and ougon as an active ingredient, and in the nasal cavity of pigs as a liquid growth promotion agent of swine that are infusion spray or nasal cavity of a pig and a method of feeding pigs infused administration of the growth promoter intranasally spray or pigs intranasally pig as a liquid.
本発明の鼻腔投与用発育促進剤を家畜の鼻腔に投与することによって、少量の使用で優れた発育促進効果が得られるようになる。 By administering the growth promoting agent for nasal administration of the present invention to the nasal cavity of livestock, an excellent growth promoting effect can be obtained with a small amount of use.
本発明の鼻腔投与用発育促進剤は、ハーブ類を水等を用いて煎じて抽出したりあるいはエチルアルコール等の有機溶媒で抽出したりした抽出物を有効成分とするものである。ハーブ抽出物を得る場合のハーブ類の使用量は、ハーブ類の種類によっても異なるが、一般的に抽出に使用する溶液に対して１〜５０重量％使用することが好ましい。加熱抽出した場合は、そのままあるいは蒸発した分量だけ補って使用することができる。また本発明は抽出液を例えば蒸留等して抽出物を粉末状とすることもできる。
本発明の鼻腔投与用発育促進剤は、液体として家畜の鼻腔内に噴霧あるいは点滴投与することが好ましい。鼻腔内に噴霧等する鼻腔投与用発育促進剤は、抽出成分濃度として０．０１〜１０％のものを使用することが好ましい。
The growth promoting agent for nasal administration of the present invention comprises an extract obtained by decocting herbs with water or the like, or extracting with an organic solvent such as ethyl alcohol. The amount of herbs used in obtaining the herb extract varies depending on the kind of herbs, but it is generally preferable to use 1 to 50% by weight based on the solution used for extraction. When extracted by heating, it can be used as it is or supplemented by the evaporated amount. In the present invention, the extract can also be powdered by, for example, distillation of the extract.
The growth promoting agent for nasal administration of the present invention is preferably sprayed or instilled as a liquid into the nasal cavity of livestock. The growth promoting agent for nasal administration that is sprayed into the nasal cavity is preferably used with an extract component concentration of 0.01 to 10%.
また本発明の鼻腔投与用発育促進剤は、畜種によっても異なるが、１回０．１〜１０mlを週に１〜３回程度鼻腔内に投与することによって目的を達成することができる。 The growth promoter for nasal administration of the present invention varies depending on the breed, but the object can be achieved by administering 0.1 to 10 ml once into the nasal cavity about 1 to 3 times a week.
本発明の鼻腔投与用発育促進剤に用いられるハーブ類としては、クローブ、オレガノ、タイム、オールスパイス、ローズマリー、シナモン、ベイリーフ、タラゴン、レモングラス、クミン、ダイオウ、オウレン、オウバク、オウゴン、ゲンノショウコ、カンゾウ、エンメイソウ、チユ、ホップ、サンシュユ、ゴバイシ、タンジン、アロエ、ウバイ等が挙げられ、これらの少なくとも１種を選択して用いることができる。 Herbs used in the growth promoter for nasal administration of the present invention include clove, oregano, thyme, allspice, rosemary, cinnamon, bay leaf, tarragon, lemongrass, cumin, diou, auren, awaku, ougon, geno shouko, Examples include licorice, enamel, chiyu, hop, sanshuyu, gobaishi, tanjin, aloe, and ubai. At least one of these can be selected and used.
本発明の鼻腔投与用発育促進剤が用いられる家畜としては、豚、牛、鶏、馬、羊、山羊、ウズラ、アヒル、ダチョウ等が挙げられる。 Examples of domestic animals to which the growth promoting agent for nasal administration of the present invention is used include pigs, cows, chickens, horses, sheep, goats, quails, ducks, ostriches and the like.
次に本発明をさらに具体的に説明するために実施例を掲げるが、本発明は、以下の実施例のみに限定されるものではない。 Next, examples are given to describe the present invention more specifically, but the present invention is not limited to the following examples.
実施例
鼻腔投与用発育促進剤の調製
表１に示すハーブ粉末４重量部を市販のダシ取り用ナイロンバックに入れてバックの口をひもでしばる。次に、水１００重量部を加熱して沸騰させ、ここにナイロンバック入りハーブ粉末を投入して１時間煎じた後放冷する。室温前後に冷ましてからナイロンバックを取り出した後ガーゼを４重に重ねた濾布で濾過する。得られた濾液に水を補って１００重量部に調整し、これを２０倍に希釈して鼻腔投与用発育促進剤を調製する。
Example
Preparation of growth promoting agent for nasal administration 4 parts by weight of the herb powder shown in Table 1 is put in a commercially available nylon bag for removing dashi and the mouth of the bag is tied with a string. Next, 100 parts by weight of water is heated and boiled, herb powder with nylon bag is added thereto, decocted for 1 hour, and then allowed to cool. After the nylon bag is taken out after cooling to around room temperature, it is filtered through a filter cloth with four layers of gauze. The obtained filtrate is supplemented with water to adjust to 100 parts by weight, and this is diluted 20 times to prepare a growth promoter for nasal administration.
豚の飼育試験
供試豚（マイティーＬＷ）を１区１３頭用いて２週間飼育した。この飼育期間中表１に示す鼻腔投与用発育促進剤および水道水を１回約１．６ml（各鼻腔（左と右）０．８mlずつ）供試豚の鼻腔内に週３回噴霧投与する。その試験結果を示せば表１のとおりである。
表１の試験結果より明らかなように、水道水を用いた区と比較し、鼻腔投与用発育促進剤を用いた区のいずれもが増体重、飼料要求率ともに改善されていることがわかる。
Pig breeding test pigs (Mighty LW) were reared for 2 weeks using 13 cats in 1 ward. During this breeding period, the growth promoting agent for nasal administration shown in Table 1 and tap water are sprayed into the nasal cavity of each test pig about 1.6 ml (each nasal cavity (left and right) 0.8 ml) three times a week. . The test results are shown in Table 1.
As is clear from the test results in Table 1, it can be seen that both the weight gain and the feed demand rate are improved in the group using the growth promoter for nasal administration compared to the group using tap water.
Claims (2)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003293271A JP4568487B2 (en) | 2003-08-14 | 2003-08-14 | Growth promoting agent for nasal administration of livestock and method for raising livestock |
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| Application Number | Priority Date | Filing Date | Title |
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| JP2003293271A JP4568487B2 (en) | 2003-08-14 | 2003-08-14 | Growth promoting agent for nasal administration of livestock and method for raising livestock |
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| Publication Number | Publication Date |
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| JP2005060318A JP2005060318A (en) | 2005-03-10 |
| JP4568487B2 true JP4568487B2 (en) | 2010-10-27 |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61263924A (en) * | 1985-05-16 | 1986-11-21 | Tsumura Juntendo Inc | Nasal drop |
| JPH01185267A (en) * | 1988-01-19 | 1989-07-24 | Geran Kaihatsu Kenkyusho:Kk | New inhalator |
| WO1995034218A1 (en) * | 1994-06-16 | 1995-12-21 | Yamanouchi Pharmaceutical Co., Ltd. | Feed containing crude drug |
| JPH11130689A (en) * | 1997-10-27 | 1999-05-18 | Nisshin Flour Milling Co Ltd | Agent for preventing and treating swine disease |
| JP2002360186A (en) * | 2001-06-13 | 2002-12-17 | Bussan Biotech Kk | Growth promotant containing herb |
-
2003
- 2003-08-14 JP JP2003293271A patent/JP4568487B2/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61263924A (en) * | 1985-05-16 | 1986-11-21 | Tsumura Juntendo Inc | Nasal drop |
| JPH01185267A (en) * | 1988-01-19 | 1989-07-24 | Geran Kaihatsu Kenkyusho:Kk | New inhalator |
| WO1995034218A1 (en) * | 1994-06-16 | 1995-12-21 | Yamanouchi Pharmaceutical Co., Ltd. | Feed containing crude drug |
| JPH11130689A (en) * | 1997-10-27 | 1999-05-18 | Nisshin Flour Milling Co Ltd | Agent for preventing and treating swine disease |
| JP2002360186A (en) * | 2001-06-13 | 2002-12-17 | Bussan Biotech Kk | Growth promotant containing herb |
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| Publication number | Publication date |
|---|---|
| JP2005060318A (en) | 2005-03-10 |
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