JP4093838B2 - Fiber treatment agent and fiber material - Google Patents

Description

【００２７】
閉鎖法のパッチテストの結果から、本発明に係るγ−リノレン酸ショ糖エステルを含む脂肪酸ショ糖エステルで加工した実施例１では、未加工布で同様のパッチテストを行ったものと比較して、炎症が緩和されていることがわかる。また、マイクロカプセル化品を用いた実施例２の結果からも同様の炎症緩和作用があることがわかる。γ−リノレン酸ショ糖エステルと抗炎症剤を併用した実施例３では、抗炎症剤を単独で使用した比較例１の結果との比較から、γ−リノレン酸本来の皮膚保護作用、抗炎症剤の経皮吸収促進作用が相まって、皮膚保護作用が向上していることがわかる。
【００２８】
【発明の効果】
本発明の繊維用処理剤を用いることにより、容易に皮膚保護作用のある繊維製品の製造が可能となる。また、本発明の繊維用処理剤を用いればその繊維材料に固着している皮膚保護性のある化合物を少量ずつ長期にわたり経皮吸収させることができ、アトピー性皮膚炎の人や敏感肌の人が、日常的に用いている化粧品、毛髪洗浄剤、食器洗浄剤などに含まれる界面活性剤によって被る肌トラブルを防止することが期待できる。したがって、本発明の繊維用処理剤を用いた繊維材料は、下着、ファンデーション、ストッキング、靴下、手袋等の直接肌に接するような衣類に対し非常に有用である。[0001]
BACKGROUND OF THE INVENTION
The present invention relates to a fiber treatment agent for the purpose of reducing skin sensitization and a fiber material treated with the fiber treatment agent.
[0002]
[Prior art]
γ-Linolenic acid is an n-6 unsaturated fatty acid that has a vasodilatory action, an antihypertensive action, a platelet aggregation inhibitory action, a skin moisturizing effect, and an atopic dermatitis improving effect. This is usually taken as food or health food, but application to textile products is also being attempted. For example, JP-A-8-337918 (Patent Document 1) discloses a γ-linolenic acid-containing rayon fiber obtained by adding and mixing an emulsion of γ-linolenic acid to viscose just before spinning and spinning. JP-A-11-107163 (Patent Document 2) discloses fibers treated with a fiber treatment agent in which γ-linolenic acid is added to emulsified or microencapsulated fats and oils. 161428 (Patent Document 3) discloses a γ-linolenic acid-containing fiber obtained by adding an emulsion containing γ-linolenic acid together with an antioxidant to a spinning solution and spinning.
[0003]
[Patent Document 1]
JP-A-8-337918 [Patent Document 2]
JP-A-11-107163 [Patent Document 3]
Japanese Patent Laid-Open No. 2002-161428
[Problems to be solved by the invention]
The use of γ-linolenic acid in the prior art as described above is intended to alleviate irritation due to the moisturizing effect on the skin of γ-linolenic acid. However, since γ-linolenic acid is an n-6 unsaturated fatty acid, it is liable to be altered by acid, alkali, oxygen, and light, and if an antioxidant is added to prevent alteration, conversely This may result in irritation to the skin and may deviate from the original purpose of providing γ-linolenic acid. In addition, since γ-linolenic acid is a fatty acid, it is easily removed by washing using a general detergent containing an alkali builder, has no durability as a processed fiber product, and has a odor peculiar to fatty acids. Improvements are required in terms of processing discoloration and the like.
[0005]
[Means for Solving the Problems]
As a result of intensive studies to solve the above-mentioned problems, the present inventor not only has the original action of γ-linolenic acid by using an esterified product of fatty acid containing γ-linolenic acid and sucrose. Furthermore, by having permeability to the skin, it also functions as a transdermal absorption enhancer such as other functional substances such as anti-inflammatory agents, and also contains fatty acid (γ-linolenic acid) salt containing a polyester body having a triester or higher. It was found that the use of a sugar ester makes it possible to produce a fiber material that is chemically stable and has the effect of reducing skin sensitization and the durability of the effect. is there.
[0006]
That is, this invention provides the processing agent for fibers characterized by containing the fatty acid sucrose ester containing (gamma) -linolenic acid sucrose ester.
[0007]
In the fiber treatment agent according to the present invention, the fatty acid sucrose ester contains 40 to 95% by mass of a polyester body having a triester or more, and the content of γ-linolenic acid in the fatty acid is 5% by mass or more. Is preferred.
[0008]
The present invention also provides a fiber material characterized in that a fatty acid sucrose ester containing γ-linolenic acid sucrose ester is fixed to the fiber.
[0009]
In the fiber material according to the present invention, it is preferable that the fatty acid sucrose ester contains 40 to 95% by mass of a polyester body having a triester or higher, and the content of γ-linolenic acid in the fatty acid is 5% by mass or higher.
[0010]
DETAILED DESCRIPTION OF THE INVENTION
The fatty acid sucrose ester used in the present invention is a fatty acid sucrose ester having a composition ratio of 10% by mass or less for a monoester, 5 to 50% by mass for a diester, and 40 to 95% by mass of a polyester having a triester or higher. It is preferable that these fatty acid sucrose esters can be easily synthesized by a conventionally known Hass-Snel method, Nebraska-Snell method or the like. The fatty acid containing γ-linolenic acid used as a raw material for the fatty acid sucrose ester is not particularly limited. For example, Mortierella isabelliina, which is a kind of microorganisms and filamentous fungi using evening primrose oil, borage oil, or glucose as a main raw material. Fatty acids derived from Mortiera oil obtained from γ-linolenic acid may be used after purification, but may also be used as an oil containing γ-linolenic acid. In this case, the concentration of γ-linolenic acid is preferably 5% by mass or more, particularly preferably 10% by mass or more.
[0011]
The fiber treating agent of the present invention is not capable of fulfilling the intended function of the present invention even in the form of a solution in which a fatty acid sucrose ester containing γ-linolenic acid sucrose ester is dissolved in an organic solvent. However, in consideration of environmental burdens, it is desirable to process the fiber as an aqueous emulsion or microencapsulated product. In preparing an emulsified product or a microencapsulated product, the fatty acid sucrose ester may be used alone, or may be used in combination with another ester compound having a moisturizing action. The ester compound used in this case is not particularly limited. For example, alkyl benzoate, cetyl ethyl hexanoate, isocetyl stearate, isocetyl neopentanoate, tridecyl neopentanoate, myristyl myri Carboxylic acid alkyl esters such as state, isopropyl myristate, ethylhexyl hydroxystearate, ethylhexyl stearate, capric triglyceride, pentaerythrityl tetracaprylate, pentaerythrityl tetraisostearate, almond oil, apricot seed oil, shea seed Examples thereof include ester oils such as oil, olive oil, sesame oil, safflower oil, avocado oil, jojoba oil, soybean oil and coconut oil.
[0012]
The emulsifier used for making an emulsified product is not particularly limited, but the following emulsifiers can be usually mentioned. Specifically, for example, higher alcohol alkylene oxide adduct, alkylphenol alkylene oxide adduct, styrenated alkylphenol alkylene oxide adduct, styrenated phenol alkylene oxide adduct, fatty acid alkylene oxide adduct, polyhydric alcohol fatty acid ester alkylene oxide addition Products, higher alkylamine alkylene oxide adducts, fatty acid amide alkylene oxide adducts, oil and fat alkylene oxide adducts, polypropylene glycol ethylene oxide adducts and other polyalkylene glycol type nonionic surfactants, glycerol fatty acid esters, pentaerythritol Fatty acid ester, fatty acid ester of sorbitol or sorbitan, fatty acid ester of sucrose, polyvalent alcohol Polyhydric alcohol type nonionic surfactants such as Cole alkyl ethers, fatty acid amides of alkanolamines, carboxylate type anionic surfactants such as fatty acid soaps, higher alcohol sulfates, higher alkyl polyalkylene glycol ether sulfates Salts, sulfated oils, sulfated fatty acid esters, sulfated fatty acids, sulfated salt type anionic surfactants such as sulfated olefins, alkylbenzenesulfonates, alkylnaphthalenesulfonates, formalin condensates such as naphthalenesulfonate, α -Sulfonate type anionic surfactants such as olefin sulfonate, paraffin sulfonate, Igepon T type sulfonate, sulfosuccinic acid diester salt, and phosphate ester type anion interface such as higher alcohol phosphate ester salt There are activators.
[0013]
Furthermore, as a stabilizer, for example, polyvinyl alcohol, methylcellulose, propylcellulose, carboxymethylcellulose, hydroxyethylcellulose, xanthan gum, starch paste and the like can be used.
[0014]
As a method for microencapsulation, various conventional methods can be adopted. However, the method of encapsulating in a capsule composed of a water-soluble polymer and a polyvalent isocyanate compound is an external factor, for a long time. It is preferable in terms of enforceability. The water-soluble polymer used at this time is not particularly limited. For example, poval, carboxymethylcellulose, dextrin, xanthan gum, curdlan, pullulan, cycloamylose, chitosan, sodium hyaluronate, sodium alginate, gelatin, gum arabic, Examples thereof include polysaccharides such as agar, polyvinylamine, polyallylamine, polydiallylamine and the like, and these water-soluble polymers may be used alone or in combination of two or more. In addition, the polyvalent isocyanate compound is a compound having two or more isocyanate groups, such as tolylene diisocyanate, xylylene diisocyanate, naphthalene diisocyanate, diphenylmethane diisocyanate, hexamethylene diisocyanate, Isophorone diisocyanates and their adducts, adducts of trimethylolpropane and tolylene diisocyanate, and their prepolymers, as well as addition of ethylene oxide and propylene oxide to make these isocyanates water-soluble Etc. These polyvalent isocyanate compounds may be used alone or in combination of two or more. Although there is no restriction | limiting in particular about the usage-amount of these polyvalent isocyanate compounds and the said water-soluble polymer, As an equivalent ratio of an isocyanate group and a hydroxyl group, a carboxyl group, or an amino group, (-NCO / -OH) ( -NCO / -COOH) or (-NCO / -NH ₂₎ is preferably used in a ratio such that 0.5 to 2.
[0015]
The fatty acid sucrose ester containing the γ-linolenic acid sucrose ester of the present invention is an improvement of the skin moisturizing effect and atopic dermatitis in addition to the vasodilatory action, antihypertensive action and platelet aggregation inhibiting action inherent to γ-linolenic acid Not only has effects such as effects, but also has an effect as a percutaneous absorption enhancer of other functional substances by having an osmotic effect on the skin. It is possible. Other functional substances that can be used in combination with γ-linolenic acid sucrose ester are not particularly limited, but anti-inflammatory agents, antiallergic agents, slimming agents, tightening agents, antioxidants, whitening agents, blood circulation promoters, etc. Is mentioned. More specifically, ε-aminocaproic acid, lysozyme chloride, guaiazulene, allantoin, glycyrrhizic acid and its salt, ellagic acid and its salt, ursolic acid and its salt, oleanolic acid and its salt, tannin, catechins, amino acid derivatives, Examples include ascorbic acid and its derivatives, tocopherol acetate, γ-oryzanol, and plant extract.
[0016]
The fiber used in the fiber material of the present invention is not particularly limited, natural fibers such as cotton, silk, and wool, regenerated fibers such as rayon, semi-synthetic fibers such as acetate, vinylon, polyester, nylon, polyethylene, polypropylene, polyurethane, Synthetic fibers such as polyaramid fibers, composite fibers of these fibers, and the like are used, and examples of the form include yarns, knitted fabrics, woven fabrics, and nonwoven fabrics.
[0017]
The fixed amount of γ- linolenic acid sucrose ester when processing the fibers by fiber-processing agent of the present invention is not particularly limited, fibers (e.g., fabrics having a basis weight of 150g / m ²⁾ 1m ² per 5 It is preferably ˜1000 mg, particularly preferably 10 to 600 mg. If the amount of fixation is less than 5 mg, the effect tends to be insufficient. On the other hand, if it exceeds 1000 mg, it is difficult to obtain a skin sensitization reduction effect commensurate with the amount used, which tends to be economically disadvantageous.
[0018]
In the present invention, a method for fixing an emulsified product or a microencapsulated product of a fatty acid sucrose ester containing γ-linolenic acid sucrose ester to the fiber may be a conventionally known method, such as a spray method, a pad method, a dipping method, or a coating. The fiber material of the present invention is obtained by adhering to a fiber by a method or the like, then drying, and optionally fixing by heat treatment. Furthermore, in order to obtain the durability of the treatment effect, a crosslinking agent and a binder can be used together as necessary. Further, by using in combination with a fiber treating agent having other functions such as a softening agent, an antistatic agent, and an antibacterial deodorizing agent, a wide variety of fiber processing becomes possible. Furthermore, the fiber treating agent of the present invention can also be used as a rinse agent after washing.
[0019]
Although there is no restriction | limiting in particular as a use of the fiber material obtained by this invention, For example, forms, such as an underwear, a foundation, stockings, socks, a glove, are mentioned, It is preferable to use as a thing which touches skin directly.
[0020]
【Example】
EXAMPLES Hereinafter, although an Example demonstrates this invention further, this invention is not restrict | limited at all by these Examples.
[0021]
In the examples, skin sensitization was evaluated by processing cotton knitted with an emulsified product or microencapsulated product of fatty acid sucrose ester containing γ-linolenic acid sucrose ester according to the present invention. About what apply | coated benzalkonium chloride known as a flame-causing substance which raise | generates a flame, the patch test for 24 hours was performed, the state of the skin was observed, and evaluation was performed.
[0022]
Example 1
CRODESTA GAMMA (produced by Croda Co., Ltd., 64 mass% triester, 25 mass% of γ-linolenic acid in fatty acid) as fatty acid sucrose ester containing γ-linolenic acid sucrose ester, polyoxyethylene sorbitan ester as emulsifier 20 g of Rheodor TWO-320 (manufactured by Kao Corporation) and 880 g of water were added, and the mixture was stirred at 3000 rpm using a laboratory homomixer to obtain an emulsion product of 10% by mass of fatty acid sucrose ester. The average particle size of this emulsified product was 10.5 μm. A 1% by mass aqueous dispersion of this emulsified product was adhered to a cotton knitted fabric (weight per unit: 150 g / m ² ) at a drawing rate of 60% by mass, and then dried at 120 ° C. for 5 minutes. On this processed cloth 1cm x 1cm, 50μL of 1% by weight benzalkonium chloride aqueous solution is spotted, and a patch test is performed for 20 subjects by the closure method for 24 hours. Table 1 shows the results of evaluation according to the following five-stage evaluation criteria depending on the state of.
[0023]
A: no reaction B: erythema only C: erythema, papules D: erythema, papules, small blisters E: large blisters Example 2
CRODESTA GAMMA (manufactured by CRODA Co., Ltd.) 50 g, isopropyl myristic acid ester 50 g, polyvinyl alcohol 10 mass% aqueous solution 200 g, hexamethylene diisocyanate trimer 50 g, and water 650 g were stirred at 8000 rpm using a laboratory homomixer at room temperature. And a primary emulsion was obtained. Next, the temperature was raised to 70 ° C. and reacted at the same temperature for 5 hours to obtain a microencapsulated product of 10% by mass of a mixture of fatty acid sucrose ester and isopropyl myristate ester. The average particle size of this microencapsulated product was 2.4 μm. Table 1 shows the results of processing using the 1% by mass dispersion of this microencapsulated product in the same manner as in Example 1 and evaluating the skin sensitization.
[0024]
Example 3
CROBESTA GAMMA (manufactured by Croda Co., Ltd.) 50 g, isopropyl myristic acid ester 40 g, ellagic acid 10 g, polyvinyl alcohol 10 mass% aqueous solution 200 g, hexamethylene diisocyanate trimer 50 g, water 650 g at room temperature using a laboratory homomixer. The mixture was stirred at 8000 rpm to obtain a primary emulsion. Next, the temperature was raised to 70 ° C. and reacted at the same temperature for 5 hours to obtain a microencapsulated product of 10% by mass of a mixture of fatty acid sucrose ester, isopropyl myristate ester and ellagic acid. The average particle size of the microencapsulated product was 2.8 μm. Table 1 shows the results of processing using the 1% by mass aqueous dispersion of this microencapsulated product in the same manner as in Example 1 and evaluating skin sensitization.
[0025]
Comparative Example 1
90 g of isopropyl myristic acid ester, 10 g of ellagic acid, 200 g of a 10% by weight aqueous solution of polyvinyl alcohol, 50 g of hexamethylene diisocyanate trimer, and 650 g of water are stirred at 8000 rpm at room temperature using a laboratory homomixer to obtain a primary emulsion. It was. Next, the temperature was raised to 70 ° C. and reacted at the same temperature for 5 hours to obtain a microencapsulated product of 10% by mass of a mixture of isopropyl myristic acid ester and ellagic acid. The average particle size of this microencapsulated product was 5.1 μm. Table 1 shows the results of processing using the 1% by mass aqueous dispersion of this microencapsulated product in the same manner as in Example 1 and evaluating skin sensitization.
[0026]
[Table 1]

[0027]
From the results of the patch test of the closure method, in Example 1 processed with the fatty acid sucrose ester containing γ-linolenic acid sucrose ester according to the present invention, compared with the one subjected to the same patch test with an unprocessed cloth It can be seen that the inflammation is alleviated. Moreover, it can be seen from the results of Example 2 using the microencapsulated product that there is a similar inflammation-reducing action. In Example 3 in which γ-linolenic acid sucrose ester and an anti-inflammatory agent were used in combination, a comparison with the results of Comparative Example 1 in which the anti-inflammatory agent was used alone showed that γ-linolenic acid had an original skin protective action and an anti-inflammatory agent. It can be seen that the skin protective effect is improved by the combined percutaneous absorption promoting action.
[0028]
【The invention's effect】
By using the fiber treating agent of the present invention, it is possible to easily produce a fiber product having a skin protecting action. In addition, if the fiber treatment agent of the present invention is used, the skin-protective compound adhering to the fiber material can be percutaneously absorbed little by little over a long period of time, and people with atopic dermatitis or sensitive skin However, it can be expected to prevent skin problems caused by surfactants contained in daily cosmetics, hair cleaners, dishwashing agents, and the like. Therefore, the fiber material using the fiber treating agent of the present invention is very useful for clothing such as underwear, foundations, stockings, socks, gloves and the like that directly touches the skin.

Claims (4)

A treating agent for fibers comprising a fatty acid sucrose ester including γ-linolenic acid sucrose ester. The processing agent for fibers according to claim 1, wherein the fatty acid sucrose ester contains 40 to 95% by mass of a polyester body having a triester or higher and the content of γ-linolenic acid in the fatty acid is 5% by mass or more. A fiber material, wherein a fatty acid sucrose ester containing γ-linolenic acid sucrose ester is fixed to the fiber. The fiber material according to claim 3, wherein the fatty acid sucrose ester contains 40 to 95% by mass of a polyester body having a triester or more, and the content of γ-linolenic acid in the fatty acid is 5% by mass or more.