JP4005373B2 - Solid-state imaging device - Google Patents

Description

[0001]
BACKGROUND OF THE INVENTION
The present invention relates to an optical imaging system individual imaging device for imaging a micro-sized individual dispersed in a solution, and in particular, an individual that captures an image by loading a sampling kit including such an imaging target individual on a stage. The present invention relates to an imaging apparatus and a mounting apparatus for mounting a collection kit used in such an individual imaging imaging apparatus.
[0002]
[Prior art]
In order to measure the number of particles having a size equal to or larger than a predetermined diameter dispersed in the solution, the subject is irradiated with light, and the reflected light is photographed by a photoelectric conversion means such as a CCD or MOS sensor. An example of a particle number measuring apparatus that measures the number of particles present in a subject by processing is disclosed in Japanese Patent Laid-Open No. 7-49300.
[0003]
This particle number measuring device measures the number of silicon particles having a predetermined diameter or more in a dispersion liquid, and a filter on which a certain amount of silicon particle dispersion liquid is dropped is mounted on the mounting section, and the light emitting section emits light. The number of silicon particles is generated by irradiating the filter with light, receiving reflected light with a CCD sensor, and generating a waveform signal corresponding to the number of silicon particles having a diameter greater than or equal to a predetermined diameter based on the photoelectrically converted image signal. Is to count.
[0004]
In such a conventional individual imaging device of the optical magnification system, the filter including the individual to be imaged is placed in a stationary state at a predetermined position of the stage for placing it, and the upper part of the stage is opened. A film including an individual to be imaged as a subject is placed on the stage, and an image of the individual included in the film is captured by a CCD sensor disposed above the stage.
[0005]
[Problems to be solved by the invention]
However, when the size of the individual to be imaged is extremely small, such as a micron unit, and the stage must be divided into a plurality of imaging unit areas, the image must be taken while moving the stage in the X and Y directions. In addition, it is difficult to keep the distance between the imaging surface and the condenser lens constant. In this case, in order to accurately and clearly capture the contour of the individual, the stage must be irradiated with light rays from a plurality of directions almost uniformly, and the focal depth of the lens must be kept within a range of several tens of microns.
[0006]
In addition, there are multiple types of collection kits that include the individual to be imaged. In order to respond to this, changes based on the difference in the shape of the collection kit, tolerance of the collection kit itself, when the collection kit is placed on the stage It is necessary to consider variations in many parameters such as lifting of the collection kit, and the allowable distance range between the condenser lens and the collection kit is extremely severe.
[0007]
Further, in a film-shaped collection kit, even if the film thickness is within a certain range, air may enter and float on the lower surface of the film-shaped collection kit on the stage.
[0008]
Further, when a plurality of types of collection kits are used interchangeably, a cavity is formed below corresponding to the shape if it corresponds to a three-dimensional collection kit. If a film-shaped sampling kit is placed there, the film-shaped sampling kit hangs down in such a cavity due to the heat (infrared rays) from the light source and the weight of the sampling kit itself. It is impossible to keep the distance between the sampling kit and the sampling kit within a predetermined depth of focus range.
[0009]
The present invention provides an individual imaging apparatus that realizes irradiation of a substantially uniform light beam to the entire imaging region by a small-sized stage and a simple fixing means without mounting an automatic focus adjustment apparatus in such an individual imaging apparatus. In addition, the object of the present invention is to provide a mounting device for a sampling kit that can accommodate a plurality of types of sampling kits and that can keep the distance between the condenser lens and the sampling kit within a certain depth of focus range. .
[0010]
[Means for Solving the Problems]
For this reason, the present invention is provided with a stage on which a collection kit including an individual to be imaged is loaded, and the stage can be freely opened and closed. The predetermined thickness The imaging aperture To fix the collection kit A fixing means; a light emitting means; and a light converging means for converging light from the light emitting means and projecting the light onto the stage as a light beam, a light source for irradiating the stage with light, and a substantially vertical position of the stage Lens means for concentrating light from the individual, and photoelectric conversion means for converting the light collected by the lens means into an electrical signal, A moving means for moving the stage and the fixing means in a horizontal direction while maintaining the height of the stage surface of the stage with respect to the lens means; An imaging apparatus for individual imaging having The light emitting means is composed of a plurality of light emitting devices, and the center of the lens of the lens means is so arranged that light beams from the individual light emitting devices are projected from obliquely above the stage to substantially the same position on the stage surface. It is arranged in a symmetrical position that is equidistant facing The imaging aperture is configured so that the light beam from the light converging means is irradiated on the entire area to be read on the stage. It is a polygon having an area wider than the moving area of the reading object moved by the moving means and having an apex angle corresponding to the number of the plurality of light emitting devices as an opening allowing light from each light emitting device to pass. An individual imaging apparatus characterized by the above is provided.
[0011]
by this, In this solid-state imaging device, On a stage that forms an opening of a smaller size and shape of Light is applied to the entire area to be read Possible It was.
[0012]
here, In the individual imaging apparatus, the direction in which the moving means moves the stage is different from the diagonal direction of the imaging opening. Further, the fixing means is provided with a fixing elastic member for fixing the sampling kit. .
[0013]
By the way, the light emitting means is constituted by four light emitting devices, and in this case, the imaging opening portion forms a quadrangular shape having apexes in respective directions in which the four light emitting devices are arranged. is there .
[0014]
By the way, the collection kit used in the solid-state imaging device includes a sheet-like first collection kit and a second collection kit having a thickness larger than that of the first collection kit, and the stage has a thickness. Any one of a number of different collection kits is loaded .
[0015]
When the first collection kit is loaded on the stage, the distance between the solid imaging surface and the lens when the first collection kit is loaded is loaded with the second collection kit. An intermediate plate for height adjustment to be equal to the distance is loaded. In this case, the intermediate plate is positioned so as to support the film portion of the first collection kit. .
[0016]
DETAILED DESCRIPTION OF THE INVENTION
DESCRIPTION OF THE PREFERRED EMBODIMENTS Embodiments of a mounting apparatus for mounting an individual imaging apparatus and an individual imaging sampling kit according to the present invention will be described below in detail with reference to the drawings.
[0017]
FIG. 1 is an external perspective view of the imaging apparatus.
[0018]
In this figure, the stage is moved to a position where the collection kit can be loaded on the stage 2 and the fixing means 21 is opened.
[0019]
FIG. 2 is a front view of the entire imaging apparatus 1. The imaging apparatus 1 includes a stage 2 on which a subject to be examined is placed, a front cover 5 that is opened and closed to perform operations such as placing a specimen on the stage 2, a light source unit 4 that irradiates a subject subject with light, A lens unit 3 that receives two-dimensional image light from a subject that has been irradiated by a light source unit 4 and emits excitation light from a reagent and converts the light into an electric signal image, supports a plurality of filters, and filters according to switching of light emission And a X moving table 23 and a Y moving table 26 for moving the position from the operability when placing the specimen on the previous stage 2.
[0020]
Here, the stage 2 is a fixing means for fixing the upper surface of the table and the sampling kit. As The emblem collection kit 40 or the film collection kit 41, which is formed between the collection kit holder 21 and to which a specimen is attached, is for mounting.
[0021]
At the bottom of the Y table 26, Stage 2 and attached to it A Y1 shaft 29 and a Y2 shaft 30 for guiding the collection kit holder 21 in the vertical axis direction (the arrow Y direction in FIG. 7), and a Y1 sleeve 31 and a Y2 sleeve 32 that are slidably fitted to these shafts, respectively. Is provided. At the bottom of the X table 25, Stage 2 and attached to it An X1 shaft 27 and an X2 shaft 28 for guiding the collection kit holder 21 in the horizontal axis direction (the arrow X direction in FIG. 7), and an X1 sleeve 33 and an X2 sleeve 34 that are slidably fitted to these shafts, respectively. Is provided. The Y table 26 and the X table 25 are moved by being pulled by a belt by a Y driving unit (driving in the arrow Y direction, not shown) and an X driving unit (driving in the arrow X direction, not shown), respectively. .
[0022]
Even when the apparatus is imaging an object to be imaged, the table 20 is released when the front cover 5 is opened and moves to the front position. The signal of the cover sensor 203 (door sensor in the block diagram of FIG. 6) 203 is transmitted to the PC and processed in the PC. The reset operation of the imaging operation in the apparatus is automatically controlled by firmware in the imaging apparatus 1, but the movement of the stage 2 at the start of imaging is performed by an initial command from a data processing apparatus (not shown). Here, the initial command is a command to move from the current position to the collection kit loading position (front).
[0023]
When the front cover 5 is opened, a signal to that effect is emitted from a cover sensor (not shown). At the start of imaging, the stage 2 moves to the front where the front cover 5 is opened based on a movement command from a data processing device (not shown) that has received this signal. The front cover 5 is flipped upward by a coil spring 5a so as to be kept open.
[0024]
When the subject (specimen) of the emblem collection kit 40 or the film collection kit 41 is mounted on the stage 2 and the front cover 5 is closed by the operator's hand, the signal of the cover sensor is sent to the data processing apparatus connected to the interface. And the fact that the imaging preparation state is ready is displayed on the display. The operator instructs an external data processing device to start measurement. The instructed data processing apparatus sends a measurement start command to the imaging apparatus. The control unit of the imaging apparatus controls the Y drive unit (not shown) to move the stage 2 to the home position, that is, the initial position of the shooting position. The data processing apparatus need not be a dedicated or high-performance data processing apparatus, and a general personal computer is sufficient.
[0025]
FIG. 3 is a diagram of the stage 2 in the imaging apparatus observed from above. The stage 2 is irradiated with light from the light source unit 4, and the light source unit 4 includes four rod light sources 6a, 6b, 6c, and 6d. Each rod light source 6 includes substrates 50a, 50b, 50c, and 50d at end portions, and light emitting diodes are respectively installed on the substrate toward the inside of the rod.
[0026]
The rod light source 6a and the rod light source 6b emit light in the same wavelength region (main wavelength 370 nm), and the rod light source 6c and the rod light source 6d emit light in the same wavelength region (main wavelength 525 nm). A U380 filter, which is a cut filter for cutting a base portion that becomes an unnecessary frequency band in each light emitting region distribution, is provided in the rod light sources 6a and 6b, and a BP535 filter is provided in the rod light sources 6c and 6d, respectively. ing.
[0027]
The stage 2 is provided with a fixing means 21 for holding the collection kit, and an imaging opening W is provided at the center of the fixing means 21. The stage 2 moves in the X direction and the Y direction in the horizontal direction, and when the stage 2 is positioned at the initial reading setting position (center position), the opening center of the imaging opening W is the center of imaging through the lens unit 3 ( It coincides with the so-called optical axis). As for the movement from the central stop position, the stage 2 moves from left to right and up and down from the center by a half of 8.5 mm by 17 mm in both XY directions. For this reason, the imaging opening W is required to be 17 mm wider than the area 17 mm for imaging.
[0028]
Since the illumination light from the light source 6 enters obliquely with respect to the size of the opening W, it is necessary to retract the edge of the window so as not to be blocked by the thickness of the fixing means 21 having the window. For this purpose, the size of the opening W must be further enlarged. Here, when the imaging opening W is circular and has the same size as the area to be read, the light (light beam) from each rod light source 6 is blocked. For this reason, the imaging opening W must have a diameter larger than that of a circle of 34 mm so as to be larger than the diameter of the light beam so that the light beam irradiated from the rod light source 6 is not blocked.
[0029]
In this case, the size of the opening W becomes considerably large. For example, the lock portion 21a of the intermediate plate 42 used when using the film collecting kit needs to be further below the drawing shown in FIG. Therefore, the peripheral design is affected, and the apparatus becomes large.
[0030]
However, as shown in the figure, when the opening W is opened in a square region, the projection of the apex angles Wa, Wb, Wc, Wd allows a wide light irradiation range, and the side portion has a small overhang. The device can be made compact.
[0031]
The collection kit holder 21 for fixing the collection kit on the stage 2 is equipped with an elastic body, and the stage 2 is fixed by directly fixing the collection kit (emblem collection kit 40 or film collection kit 41). It is possible to eliminate the deviation during the movement in the XY direction.
[0032]
This fixing elastic body (set leaf spring) is an elastic plate 35 that is attached to the collection kit holder 21 and is linked to contact means (pins) attached to the collection kit holder 21 in a slidable manner. Fix by pressing the kit. If an attempt is made to provide a protrusion that contacts the contact pin on the fixing elastic body, a processing failure such as a crack may occur. In order to avoid this, a protrusion is provided on the contact pin side in this embodiment without providing a protrusion on the fixing elastic body. Furthermore, operability can be improved by attaching a handle to the film holding plate.
[0033]
In the imaging apparatus 1, a stage 2 configured to select and mount an emblem collection kit 40 or a film collection kit 41 and a collection kit holder 21 for holding the collection kit are moved in the XY directions. For this purpose, an X drive unit and a Y drive unit are provided. The stage 2 is formed between the upper surface of the upper table 20 and the collection kit holder 21, and the emblem collection kit 40 or the film collection kit 41 to which the specimen is attached is mounted.
[0034]
The collection kit holder 21 is fixed by a lock lever 22. The upper table 20 is fixed on the X table 25, and the X table 25 is fixed on the Y table 26. The upper table 20 on the X table 25 is supported at three points by three springs. The positioning jig is temporarily fixed, and the stage 20 biased by the spring comes into contact with the jig to maintain a predetermined level. Configured to sag. The levelness is maintained by screwing with a lock plate. Thereafter, the positioning jig is reattached to the camera unit 3.
[0035]
The collection kit holder 21 has a holding plate holding means located above the entrance in the vicinity of the case when moving from the front of the measurement start to prevent forgetting to close. Engagement And automatically closes with movement.
[0036]
The stage 2 on which the specimen is placed differs only in the type of collection kit installed in the collection kit holder 21, and the basic structure of both collection kits is the same. However, in the case of the film collection kit 41, the hole for allowing the emblem collection kit 40 to be loaded is closed and an intermediate plate 42 (mounting means) having a function of adjusting the height is loaded.
[0037]
FIG. 4 shows a state where the emblem collection kit 40 is mounted on the stage 2 of the imaging apparatus 1. In the emblem collection kit 40, an injection needle (not shown) is connected to the measurement unit and extends downward. The object to be inspected can be finely crushed and submerged to suck up the solution, or to directly suck up the liquid in food. The sucked liquid is impregnated in the measuring section and observed whether or not bacteria are present. A cover 20c is provided on the lower surface of the stage 2 so that even if a solution spills from the injection needle onto the apparatus, the apparatus is not affected.
[0038]
FIG. 5 shows a state where the film collection kit 41 is mounted on the stage 2 of the imaging apparatus 1. The film collection kit 41 has an adhesive surface, and a protective film is deposited during storage, but the film is removed from the object to be collected during use.
[0039]
Since the emblem collection kit 40 has a measurement unit on the upper part of the collar part 40a, the emblem collection kit 40 is higher than the collar part 40a. On the other hand, the film collection kit 41 has a film shape and does not have such a height (thickness). Furthermore, the film may bend depending on how it is pressed. On the other hand, the lens unit 3 is a magnifying optical system, and since the contour shape of the individual is important for the measurement of the number of subjects, the focal depth of shooting is extremely severely narrowed. Moreover, since the size of the bacteria to be imaged is small and on the order of μm, there are only about one pixel (one pixel is 1.6 μm). Therefore, the height of the imaging surface needs to be placed at the same level position in the two types of collection kits.
[0040]
In order to adjust the level position, when the film collection kit 41 is mounted, the intermediate plate 42 is used also as a support for the film. That is, since there is a hole 20a for inserting the emblem collection kit 40 in the stage 2, when the film collection kit 41 is loaded as it is, the central portion sinks and a desired focal position is obtained. Because it disappears. The light beam emitted from each of the rod light sources 6a, 6b, 6c, 6d does not contain a large amount of infrared components but is not completely absent. This is because the settlement of the part will be promoted.
[0041]
FIG. 6 is a block diagram illustrating control of the imaging apparatus. The imaging device (CCD) 84 is supplied with a clock and power for driving, and a video signal is output via a standard interface such as a USB. The video signal is converted into digital data by the omitted image processing circuit, and is held in the memory, and then sent from the USB controller 211 controlled by the CPU 210 to the connector 213. The USB cable 212 is sent to a main unit (personal computer) (not shown). Similarly, a control command for the imaging apparatus 1 is given from the main body device via the USB interface.
[0042]
According to the USB interface, a necessary current can be supplied from the main unit if the current is equal to or less than a predetermined current. However, the present apparatus has an X motor 200 and a Y motor 201 for driving the table, and rod light sources 6a and 6b as light sources. , 6c and 6d require a large current, so that the AC adapter 215 can be connected via the power connector 214 and is supplied with power.
[0043]
The X motor 200 and the Y motor 201 are controlled and driven by the motor driver 204 from the CPU. Further, the rod light sources 6a, 6b, 6c, and 6d, which are light sources, are driven by the transistors 205 and 206 and controlled to be lit by the CPU.
[0044]
FIG. 7 is a view for explaining details of the imaging opening W of the collection kit holder 21. In FIG. 7A, the collection kit holder 21 includes an opening (imaging opening) W0. The shape of the imaging opening W0 is substantially square except for the cut C formed on the side. In the drawing, L1, L2, L3, and L4 indicate irradiation light (light ray) spots from the respective light sources.
[0045]
As shown in FIG. 7B, the collection kit holder 21 has a considerable thickness. This is to ensure rigidity for tightening the depth of focus and the stationary position. Therefore, since each light ray entering obliquely is collected and irradiated on the central spot S1 within an unobstructed range, at least a window in the area W1 indicated by the wavy line is required. This is a case where the stage 2 does not move. Actually, the reading small area W3 located substantially at the center of the center spot S1 is repeatedly read while moving in the entire reading area W2 in the X and Y directions in the figure. Because it is.
[0046]
In FIG. 7, for easy understanding, the entire reading area W2 is drawn in a square shape, but the area including the individual to be detected is not necessarily a square, and the existence of the individual is guaranteed in the entire reading area W2. It may be a degree.
[0047]
In FIG. 7, the film collection kit 41 is taken as an example. 41 Below this is an intermediate plate 42.
[0048]
By the way, in the present embodiment, since the stage moves with the imaging position fixed, the entire area W2 moves in the area W1, which is indicated by a broken line, and is shown by the broken line when the state shown in FIG. To do. The X direction will be described as an example. At least, if there is a window in the area W1, the light beam is not blocked, but it moves by M, so the imaging aperture must be enlarged by M. Therefore, the actual imaging opening has a size of W0.
[0049]
As described above, since the imaging opening becomes large, in order to pursue a compact design as much as possible, if the apex angle of the rectangle is positioned in the direction in which the light beam is projected, the position of the side not related to the projection Should be cut out like C.
[0050]
The collection kit holder 21 is fixed between the intermediate plate 42 with the collection kit holding pin 251 urged by the elastic plate 35 holding the film collection kit 41 at the point P. The collection kit pressing pin 251 can be made compact by bringing it as close as possible to the irradiation position S1, and the subject stability in the reading target area W3 is increased.
[0051]
Further explanation will be given for the movement in the X direction. In order to set the rightmost column in the entire reading area W2 as a reading target, the imaging opening W0 is moved to the left and the wall surface A1 is located at the line position of A2. Move up. Therefore, the light spots L1 and L3 are not blocked. Similarly, in order to set the leftmost column in the entire reading area W2 as a reading target, the imaging opening W0 is moved to the right and the wall surface B1 is moved to the line position B2. Therefore, the light spots L2 and L4 are not blocked.
[0052]
Therefore, it can be said that the minimum imaging opening W1 when the stage does not move is, in other words, an area where the light beam is not blocked even when the stage (imaging opening) is moved in any direction.
[0053]
Furthermore, since the light source unit 4 of the present apparatus irradiates with the light sources arranged diagonally, the imaging opening W of the sampling kit holder 21 has an opening for allowing the inspection area to be viewed in the direction of the imaging means. The light source is arranged in a square shape with the direction in which the light source is arranged as the apex. By forming the imaging opening W in a quadrangular shape, irradiation that does not block the light beam while ensuring the surrounding meat was realized with the minimum necessary area.
[0054]
Here, the imaging operation of this apparatus will be described based on the flowchart of FIG.
[0055]
When the switch 10 of the present apparatus is pressed and the power is turned on (S1), the CPU of the main body performs an initialization operation for starting imaging (S2). When the door (front cover 5) is opened, a signal for opening the door is generated (S3). At the start of reading, the stage 2 moves to the front where the front cover 5 is opened based on a movement command from a data processing device (not shown) that has received this signal. The subject (specimen) of the emblem collection kit 40 or the film collection kit 41 is mounted on the stage 2 (S4). When the front cover 5 is closed by the operator's hand (S5), the stage moves to the origin (home position which is the initial position of the photographing position) (S6). The signal of the cover sensor is sent to the data processing device connected to the interface to indicate on the display that it is ready.
[0056]
Here, the operator instructs the data processing device (not shown) to move the stage 2 to the measurement position (S7). The LED / filter is switched (S8). A measurement start command is sent to the imaging apparatus to start measurement (S9), and data is captured (S10). When data measurement continues, the instructed data processing device sends a measurement start command to the imaging device (S12).
[0057]
The control unit of the imaging apparatus moves the stage 2 to the home position. S7 to S12 are repeated until the measurement is completed. When the measurement is completed, an initialization S operation for measuring completion is performed (S13). The stage 2 moves to the front where the front cover 5 is opened, opens the door (S14), and takes out the collected sheet (S15). Here, when there is a next collection sheet, the operations of S4 to S16 are repeated. If there is no next collection sheet, the door is closed (S17), the power is turned off, and the process ends (S18, S19).
[0058]
As described above in detail, in the individual imaging device according to the present invention, a stage on which a sampling kit including an individual to be imaged is loaded, and the stage is provided so as to be openable and closable. A fixing means having an opening, a light emitting means, a light converging means for converging the light from the light emitting means and projecting it as a light beam on the stage, and a light source for irradiating the stage with light, An imaging device for individual photographing, which is located in a substantially vertical direction of the stage and has lens means for condensing light from the individual and photoelectric conversion means for converting light collected by the lens means into an electric signal The imaging aperture is opened so that the light beam from the light converging means is irradiated over the entire area to be read on the stage. By reading forming the opening shape is to that as light is irradiated to the whole area of the target region read on stage.
[0059]
Furthermore, in the present invention, the collection kit corresponding to a plurality of types of collection kits can be provided without attaching an expensive automatic focus adjustment device by keeping the distance between the condenser lens and the collection kit within a certain depth of focus range. The mounting device was realized.
[Brief description of the drawings]
FIG. 1 is a perspective view of an imaging apparatus according to the present invention.
FIG. 2 is an overall front view of the imaging apparatus.
FIG. 3 is a plan view of a stage in the imaging apparatus observed from above.
FIG. 4 shows a state where an emblem collection kit is mounted on a stage in the imaging apparatus.
FIG. 5 shows a state where a film collection kit is mounted on a stage in the imaging apparatus.
FIG. 6 is a block diagram for explaining a control configuration of the imaging apparatus.
FIG. 7 is a view for explaining an imaging opening of the sampling kit holder.
FIG. 8 is a flowchart for explaining an outline of an imaging operation of the imaging apparatus.
[Explanation of symbols]
1 Imaging device
2 stages
3 Lens unit
4 Light source unit
5 Front cover
6a, 6b, 6c Light source
10 Power switch
20 tables
21 Collection kit holder
22 Lock lever
25 X table
26 Y table
35 Elastic plate
40 Emblem Collection Kit
41 Film collection kit
42 Intermediate plate
L1, L2, L3, L4 Irradiation light spot
W Imaging aperture

Claims (7)

A stage loaded with a collection kit containing an individual to be imaged;
A fixing means provided on the stage so as to be freely opened and closed, and having an imaging opening of a predetermined thickness and fixing the sampling kit ;
A light source for converging light from the light emitting means and projecting it as a light beam on the stage, and a light source for irradiating the stage with light;
Lens means positioned in a substantially vertical direction of the stage, and condensing light from the individual;
Photoelectric conversion means for converting the light collected by the lens means into an electrical signal;
Moving means for horizontally moving the stage and the fixing means while maintaining the height of the stage surface of the stage relative to the lens means;
An imaging apparatus for individual imaging having
The light emitting means is composed of a plurality of light emitting devices, and the center of the lens of the lens means is so arranged that light beams from the individual light emitting devices are projected from obliquely above the stage to substantially the same position on the stage surface. It is arranged in a symmetrical position that is equidistant facing
The imaging aperture has a wider area than the moving area of the reading object moved by the moving means so that the light beam from the light converging means is irradiated to the entire area of the reading object area on the stage , and An individual imaging device , wherein the aperture is a polygon that has an apex angle corresponding to the number of the plurality of light emitting devices as an opening that allows light from the light emitting devices to pass therethrough . The solid-state imaging device further solid imaging device according to claim 1 in which the direction in which it said moving means moves said stage and a diagonal direction of the image pickup opening are different from each other.   The individual imaging apparatus according to claim 1, wherein the fixing unit includes a fixing elastic member for fixing the collection kit. 2. The light emitting device according to claim 1, wherein the light emitting unit includes four light emitting devices, and the imaging opening has a quadrangular shape having apexes in respective directions in which the four light emitting devices are arranged. Solid-state imaging device . The collection kit includes a sheet-like first collection kit and a second collection kit having a thickness larger than that of the first collection kit, and the stage includes any one of a plurality of collection kits having different thicknesses. The solid-state imaging device according to claim 1, wherein one of them is loaded . When the first collection kit is loaded on the stage, the distance between the solid imaging surface and the lens when the first collection kit is loaded is loaded with the second collection kit. The solid-state imaging device according to claim 5, wherein an intermediate plate for height adjustment for equalizing the distance is loaded . The solid-state imaging device according to claim 6, wherein the intermediate plate is positioned so as to support a film portion of the first collection kit .

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