JP3926811B2 - Quantitative blood collection tool - Google Patents

Description

  The present invention relates to a simple disposable quantitative blood collecting tool for quantitatively collecting a small amount of blood.

Conventional quantitative blood sampling devices are provided with a groove-shaped quantitative portion at the tip of a synthetic resin holder, and the quantitative blood sampling device is inserted into the blood squeezed through a fingertip using a commercially available lancet. There is a device that collects a certain amount of blood and presses this quantitative blood collection tool onto the diagnostic device to transfer the blood onto the device for diagnosis (see, for example, Patent Document 1).
JP-A-11-318871

  It is an object of the present invention to provide a quantitative blood collecting tool, and to quantitatively collect blood with a simple operation and accurately. The conventional quantitative blood sampling device described above has a configuration in which blood is collected by being inserted into blood squeezed by puncturing a fingertip or the like and added to a diagnostic device. Therefore, when collecting blood, it is necessary to accumulate a certain amount of blood with the punctured fingertip facing upward. When the person to be diagnosed is an adult, the punctured fingertip can be kept upward, but since the infant is constantly moving, it is difficult to keep the punctured fingertip upward. Therefore, when the fingertip is moved, the blood of the fingertip flows and cannot be collected at the fingertip. SUMMARY OF THE INVENTION An object of the present invention is to provide a quantitative blood sampling device that can quantitatively collect blood by a simple operation even for an infant who is constantly moving.

  Further, the above-described conventional quantitative blood collection device collects blood in a groove-shaped quantitative portion and presses it on the diagnostic device, thereby transferring the blood onto the device. Since blood has viscosity, there is a risk that when the blood is transferred onto the device, the blood adheres to and remains in the groove-shaped quantification portion and the quantitative performance is impaired. Therefore, an object of the present invention is to provide a quantitative blood collecting tool that can reliably transfer all of the quantified blood to the device.

  Claim 1 of the present invention includes a sheet for attaching to the skin and a container attached to the sheet so that the sheet can be removed from the sheet, and the container is opened when the sheet is attached to the skin. The container is configured to be attached to the sheet so that the mouth is directed to the skin. In claim 2, when the surface of the sheet that sticks to the skin is defined as the back surface, a hole is provided in the sheet, a container is mounted on the front surface side of the sheet, and the opening of the container is the sheet through the hole The element peeking at the back surface side of this is limited to claim 1.

According to a third aspect of the present invention, a flange is formed in part or all of the periphery of the opening of the container, and an engaging portion that engages with the flange is provided on the sheet. An element to be mounted on the seat is limitedly added to claim 2, and claim 4 is such that the flange is slidably engaged with the engaging portion, and the flange slides. Thus, the element to be disengaged by the above is limitedly added to the third aspect. According to a fifth aspect of the present invention, the engaging portion is a pair of grooves provided so as to extend in the width direction on the sheet. The pair of grooves are parallel and opposed to each other, and at least one end of each groove comes out of the flange. Thus, the open element is limitedly added to the fourth aspect.

  Claim 1 includes a sheet and a container attached to the sheet so that the sheet can be detached from the sheet, and the opening of the container is applied to the skin when the sheet is attached to the skin. The container is attached to the sheet. When blood is collected, the opening of the container is applied to the punctured portion of the skin, the sheet is attached to the skin, and only the container is removed so that blood does not spill when the necessary blood accumulates in the container. Therefore, when the skin is punctured during blood collection, if the sheet is attached to the container before the blood accumulates and flows, the blood accumulates in the container even if the punctured skin is not facing upward. If the opening is upward only when the container is removed, blood can be collected reliably. Thereby, even an infant who is difficult to keep his / her body stationary can collect blood with a simple operation. In addition, for some reasons, blood cannot be collected by puncturing a finger for various reasons. In this case, blood is collected from other parts of the body of the subject, and the skin to be punctured is Sometimes it is not facing. In this case as well, blood can be easily collected from any part of the body, since the sheet is attached to the container before blood collects and flows in the punctured skin. In this case as well, when removing the container, the opening is directed upward. By calibrating the container, it can be quantified reliably. When there is a lot of blood, a glass rod or the like can be inserted into the container to attach and take out the blood, and the blood can be quantified. In addition, blood can be quantified by setting the container to a predetermined capacity without calibrating the container.

Diagnosis of proteins, lipids or antibodies in blood is performed using plasma as a specimen. Such a diagnosis does not require a large amount of blood and is performed by collecting blood of about 60 mm ³ . A plasma separation device for separating plasma from such a small amount of blood exists, and has a configuration in which the collected blood is diluted with a diluent, and the diluted blood is filtered through a filter to separate the plasma. Yes. In the diagnosis performed by collecting a small amount of blood, it is desirable to dilute the quantified blood without remaining in the quantitative blood collecting tool because the quantitative property is lost if the quantified blood remains attached to the quantitative blood collecting device. Therefore, the present invention has been conceived mainly for use in a plasma separation device for separating plasma from a small amount of blood. In the blood dilution method, the blood is transferred to the blood dilution liquid mixing chamber provided in the plasma separation device while the blood is put in the container, and when the dilution liquid is added to the mixing chamber and mixed with the blood, the dilution liquid removes the blood from the container. Dilute to wash away. As a result, there is an effect that it is possible to dilute almost 100% without leaving blood in the blood collecting tool.

In claim 2, when the surface of the sheet that sticks to the skin is defined as the back surface, a hole is provided in the sheet, a container is mounted on the front surface side of the sheet, and the opening of the container is the sheet through the hole Looking into the back side of Therefore, when the sheet is attached to the skin with the opening of the container being directed to the punctured portion of the skin, the container may be attached with the opening of the container being directed to the skin by holding both ends of the sheet. The opening can be easily applied to the skin and the operation is simple. In addition, since fingers and the like do not touch the container, it is possible to prevent contamination of bacteria when the blood is diluted.

According to a third aspect of the present invention, a flange is formed in part or all of the periphery of the opening of the container, and an engaging portion that engages with the flange is provided on the sheet. It is the structure with which the seat is mounted. If the container is made of plastic, the flange can be easily provided integrally, so that the manufacturing is simple and the cost can be reduced.

According to a fourth aspect of the present invention, the flange is slidably engaged with the engaging portion, and the engagement is released by sliding the flange. When the blood quantification is completed and the container containing the blood is dropped from the inlet of the blood dilution liquid mixing chamber of the plasma separation device, the sheet is first peeled off from the skin, and the container is placed in the mixing chamber while holding the sheet in hand. Insert from the entrance. Next, when the container is moved to the edge of the inlet and the sheet is moved, the flange slides with respect to the engaging portion while the container is caught on the edge of the inlet, and only the sheet moves. It will come off naturally and fall into the mixing chamber. As a result, as described above, fingers or the like do not touch the container when the container is applied to the skin, but there is an effect that the finger or the like does not touch when the container is dropped into the mixing chamber. In addition, when a sheet is attached by puncturing a relatively freely movable part such as a fingertip, the container is attached to the edge of the blood dilution liquid mixing chamber with the container attached without removing the sheet, and the fingertip is The container can be dropped into the mixing chamber by moving horizontally.

According to a fifth aspect of the present invention, the engaging portion is a pair of grooves provided so as to extend in the width direction on the sheet. The pair of grooves are parallel and opposed to each other, and at least one end of each groove comes out of the flange. This is a configuration that is open. The pair of grooves are formed by bending a thin plastic plate into a U-shape, which is easy to manufacture and can reduce the cost. Also, since the flange slides smoothly in the groove, the container slides smoothly, and the container can be reliably dropped into the mixing chamber while holding only the sheet.

  Next, the best mode for carrying out the invention will be described. The sheet 1 is made of plastic and is elongated, and a round hole 2 is provided in the center. An adhesive is applied to the entire back surface 11 of the sheet. Of course, the hole 2 is not limited to a circular shape. Further, the pressure-sensitive adhesive is not limited to that applied to the entire back surface 11 of the sheet, and may be applied partially, for example, in a stripe shape. Since the sheet 1 is thinly formed, the sheet 1 has flexibility such as a bandage and can be reliably attached to the skin. A release paper is initially affixed to the back surface 11 of the sheet, and the release paper is peeled off before use.

  A pair of opposed grooves 3 and 3 are provided on the surface of the sheet so as to extend in parallel. The grooves 3 are formed by bending both end portions of a rectangular thin plastic plate 4 into a U shape. Each groove 3, 3 is open at both ends, but may be configured to open only one end. In this case, the ends on the same side of both grooves 3 and 3 are opened. The length of the groove 3 is the same as the lateral width of the sheet 1, but is not limited to this length, and may be shorter or longer than the lateral width of the sheet 1. Further, since the plastic plate 4 is warped so that the surface on which the groove 3 is provided is convex, it can be applied to the curved skin of the subject. However, it goes without saying that the sheet 1 does not have to be warped. A hole 5 having the same shape as the hole 2 of the sheet is formed in the central portion of the plastic plate 4 in which the grooves 3 and 3 are formed. As shown in FIG. 1, the plastic plate 4 is bonded to the sheet 1, and the hole 2 of the sheet and the hole 5 of the plastic plate communicate with each other.

  The container 6 is integrally formed of plastic, and a rectangular flange 8 is provided on the edge of the cup 7. The vertical width of the flange 8 is formed slightly shorter than the distance between the bottoms of the grooves 3 and 3, and the flange 8 can slide in the grooves 3 and 3. Further, the flange 8 is warped with the same curvature as the plastic 4 described above, whereby the flange 8 slides more smoothly in the grooves 3 and 3.

The opening 9 of the cup is circular, and its inner diameter is the same as the inner diameter of the holes 2 and 5 of the sheet and the plastic plate. When the holes 2 and 5 have a shape other than a circle, the opening 9 is also formed in the same shape as the holes 2 and 5. The cup 7 is preferably transparent or translucent, and has a scale 10 for quantification. The scale 10 is 60 mm ³ , but is not limited to this value. Of course, the number of scales is not limited to one, and a plurality of scales may be attached.

  Next, a method of using the present invention will be described. First, the release paper of the sheet 1 is peeled off to prepare for blood collection. Next, the skin of the diagnosis subject is punctured with a lancet, the hole 2 of the sheet is applied to the punctured portion, and the sheet 1 is attached to the skin. After taking an appropriate amount of blood into the cup 7, the sheet 1 is peeled off from the skin with the cup 7 facing upward. The cup 7 is inserted into the inlet of the blood dilution liquid mixing chamber of the plasma separation device, the cup 7 is directed to the edge of the inlet, and the sheet 1 is moved in the length direction of the groove 3. As a result, the flange 8 slides with respect to the groove 3 while the container is caught on the edge of the inlet and only the sheet moves, so that the container naturally comes off the sheet and falls into the mixing chamber. As mentioned above, when a sheet is attached by puncturing a relatively freely movable part such as a fingertip, the container is attached to the edge of the inlet of the blood dilution liquid mixing chamber without removing the sheet. The container can be dropped into the mixing chamber by moving the fingertip horizontally.

Perspective view of the present invention Front view of container Front view of plastic plate Top view of plastic plate

Explanation of symbols

1 Sheet 2 Hole 3 Groove 4 Plastic Plate 5 Hole 6 Container 7 Cup 8 Flange 9 Opening Port 10 Scale 11 Back

Claims (5)

A sheet for attaching to the skin and a container attached to the sheet so that the sheet can be removed from the sheet, and the opening of the container is applied to the skin when the sheet is attached to the skin. A quantitative blood collecting device, wherein the container is attached to a sheet. When the surface of the sheet that sticks to the skin is defined as the back surface, a hole is provided in the sheet, a container is mounted on the front surface side of the sheet, and the opening of the container is looked into the back surface side of the sheet through the hole The quantitative blood collecting tool according to claim 1. A flange is formed in part or all of the periphery of the opening of the container, and an engaging portion that engages with the flange is provided in the sheet. The container is mounted on the sheet by engaging the flange with the sheet. The quantitative blood collecting tool according to claim 2. The quantitative blood sampling device according to claim 3, wherein the flange is slidably engaged with the engaging portion, and the engagement is released by sliding the flange. The engaging portions are a pair of grooves provided so as to extend in the width direction on the sheet, and the pair of grooves are parallel and opposed to each other, and at least one end of each groove is opened so that the flange is pulled out. The quantitative blood collecting tool according to claim 4.

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