JP3530888B2 - Blood pressure monitoring device - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION [0001] BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a method for measuring the blood pressure of a living body.
Blood pressure monitoring device that monitors for a relatively long time
It is. [0002] 2. Description of the Related Art Conventionally, a compression pressure of a cuff attached to a living body.
Of the pulse synchronizing wave generated in the process of changing
The blood pressure value of the living body is measured at a predetermined cycle based on the
Value and the pressure pulse wave sensor pressed against the radial artery of the living body.
To determine the correspondence with the magnitude of the detected pressure pulse wave.
Monitoring blood pressure values based on the actual pressure pulse wave
A blood pressure monitoring device of the type to be determined next is known. for example
For example, Japanese Unexamined Patent Publication No. Hei.
It is. According to such a blood pressure monitoring device, the patient's pulse
Since the monitored blood pressure value is obtained every beat, until the blood pressure value is obtained
Blood pressure monitoring device using only a cuff requiring a predetermined measurement time
The continuity of blood pressure monitoring is better than that of
Useful when continuous blood pressure monitoring is particularly required, such as during surgery.
Was very suitable for. [0003] However, such blood
The pressure monitoring device must maintain the accuracy of the monitored blood pressure value.
Between the blood pressure value and the magnitude of the pressure pulse wave for the purpose of
Blood using cuffs at predetermined intervals to redetermine relationships
This correspondence is appropriate because the pressure measurement is repeated
Blood pressure measurement using cuff is performed relatively frequently
This means that unnecessary burden is imposed on the living body.
There was a point. Usually, the cuff and the pressure pulse wave sensor are on the same arm.
To re-determine this correspondence.
When blood pressure measurement is performed using a pressure pulse wave sensor,
Blood pressure measurement can not be performed and some blanks in blood pressure monitoring
Although a period had occurred, blood pressure measurement using a cuff
If performed relatively frequently, this gap will increase and blood pressure monitoring
There was a disadvantage that visual continuity was reduced. [0004] The present invention has been made in view of the above circumstances.
The purpose is to
No burden, and continuity of blood pressure monitoring
To provide a blood pressure monitoring device that can be improved as much as possible
is there. [0005] [MEANS FOR SOLVING THE PROBLEMS] To achieve the above object
The gist of the present invention is that a cuff attached to a living body is used.
Change the compression pressure, and in the process of changing the compression pressure
The blood pressure value of the living body is measured based on the change in the pulse
Blood pressure measuring means for determining
A pressure pulse wave sensor that detects pressure pulse waves generated from arteries;
By activating the blood pressure measuring means at a predetermined cycle,
The magnitude of the pressure pulse wave detected by the pressure pulse wave sensor and the
Pressure pulse wave blood pressure with blood pressure value measured by blood pressure measuring means
Pressure pulse wave blood pressure correspondence relationship determination means for determining a correspondence relationship;
Monitoring based on the actual pressure pulse wave from the pressure pulse wave blood pressure correspondence
Blood comprising monitoring blood pressure value determining means for sequentially determining a blood pressure value
A pressure monitoring device, comprising: (a) an electrocardiographic lead waveform of the living body;
An electrocardiographic lead device for detecting, and (b) the pressure pulse wave sensor
Pulse wave detected by the ECG
Phase difference calculating means for calculating a phase difference from a detected electrocardiographic lead waveform
And (c) the phase difference calculated by the phase difference calculating means.
Reciprocal changevalueIs determined by the monitoring blood pressure value determining means.
Changes in monitored blood pressure valuesJudgment that comparison value is set in advance
Standard value exceededThe pressure pulse wave blood pressure correspondence function
Blood pressure measurement by the blood pressure measurement means to re-determine the person in charge
Starting means for starting the operation. [0006] In this way, the electrocardiographic lead device can
The electrocardiographic lead waveform in the living body is detected, and the pressure pulse wave sensor
When a pressure pulse wave generated from a living artery is detected,
The phase difference between the ECG lead waveform and the pressure pulse wave is calculated by a phase difference calculating means.
Is calculated by Also, the monitoring blood pressure value determining means
The monitoring blood pressure value is determined based on the pressure pulse wave. And
Change of reciprocal of these phase differencesvalueAnd example of monitoring blood pressure values
For example, changes in systolic blood pressureThe comparison value with the value
Threshold exceededBased on the
The blood pressure measuring means for re-determining the pressure pulse pressure blood pressure correspondence.
The blood pressure measurement operation using the cuff by the step is activated.
Therefore, the reciprocal of the phase difference between the ECG lead waveform and the pressure pulse wave is
The change tendency is proportional to the change tendency of the monitored blood pressure value.
Phase based on the findings that have already been found experimentally
The change trend of the reciprocal of the difference is different from the change trend of the monitored blood pressure value.
In other words, if the reliability of the monitored blood pressure value is suspected
The blood pressure measurement operation using the cuff is started.
Blood pressure measurement using a cuff to re-determine the correspondence
It is possible to set the repetition cycle to a relatively long time.
The frequency of blood pressure measurement using the cuff is reduced,
The pressure on the patient and the continuity of blood pressure monitoring
Can be improved as much as possible. [0007] BRIEF DESCRIPTION OF THE DRAWINGS FIG.
A detailed description will be given based on this. FIG. 1 shows an embodiment of the present invention.
FIG. 2 is a diagram illustrating a configuration of a blood pressure monitoring device 8. In FIG. 1, a blood pressure monitoring device 8 is made of rubber.
The bag is contained in a cloth band bag, for example, the upper arm 12 of the patient.
Cuff 10 wound around the cuff 10 and a pipe 20
Pressure sensor 14, switching valve 16,
And an air pump 18. This switching valve 16
Is a pressure supply state that allows the supply of pressure into the cuff 10
State, a slow exhaust pressure state in which the cuff 10 is gradually exhausted, and
Three states of rapid exhaust pressure state in which the inside of the cuff 10 is exhausted rapidly.
Is configured to be switchable. The pressure sensor 14 detects the pressure inside the cuff 10.
And outputs a pressure signal SP representing the pressure to the static pressure discrimination circuit 2
2 and the pulse wave discrimination circuit 24. Static pressure valve
The separate circuit 22 has a low-pass filter,
Cuff pressure signal representing the contained steady pressure or cuff pressure
The cuff pressure signal SK is discriminated from the A / D converter 26.
To the electronic control unit 28 via the Pulse wave discrimination circuit 2
Numeral 4 is provided with a band-pass filter, and generates a vibration of the pressure signal SP.
Pulse wave signal SM₁The frequency of the pulse wave
Signal SM₁Via the A / D converter 30
8 This pulse wave signal SM₁The cuff pulse wave represented by
Generated from the brachial artery (not shown) in synchronization with the patient's heartbeat
This is a pressure vibration wave transmitted to the cuff 10. The electronic control unit 28 includes a CPU 29, R
OM31, RAM33, and I / O port not shown
And a so-called microcomputer with
The CPU 29 executes the program stored in the ROM 31 in advance.
Signal processing while utilizing the storage function of the RAM 33 according to the RAM.
Drive signal from the I / O port
Outputs to control the switching valve 16 and the air pump 18. The pressure pulse wave detection probe 34 is connected to the cuff 10.
On the downstream side of the artery of the upper arm 12 of the patient
And the open end of the housing 36 having a container shape is
8 on the wrist 42 with the wearing band 40
It is designed to be removable. housing
36, a pressure pulse wave sensor is provided through a diaphragm 44.
The support 46 is relatively movable and can be moved from the open end of the housing 36.
Of the housing 3
6 and a pressure chamber 48 are formed by the diaphragm 44 and the like.
Have been. An air pump 50 is provided in the pressure chamber 48.
Pressure air is supplied through the pressure regulating valve 52
As a result, the pressure pulse wave sensor 46
Pressing force P according to pressure_HDAt the body surface 38
You. The pressure pulse wave sensor 46 is, for example, a single crystal.
A large number of pressing surfaces 54 of a semiconductor chip made of silicon or the like
A semiconductor pressure-sensitive element (not shown) is arranged and configured.
And is pressed onto the radial artery 56 on the body surface 38 of the wrist 42
By generating from the radial artery 56, the body surface 38
The transmitted pressure vibration wave or pressure pulse wave is detected and the pressure
Pressure pulse wave signal SM representing pulse wave_TwoThrough the A / D converter 58
To the controller 28. The lower waveform in FIG.
8 shows an example of a pressure pulse wave detected by the wave sensor 46.
You. The CPU 29 of the electronic control unit 28
Is based on a program stored in the ROM 31 in advance.
A drive signal is output to the air pump 50 and the pressure regulating valve 52,
The pressure in the pressure chamber 48, ie, the skin of the pressure pulse wave sensor 46
Adjust the pressing force for This makes it possible to monitor blood pressure
The pressure pulse sequentially obtained in the pressure change process in the pressure chamber 48
Pressure P of the pressure pulse wave sensor 46 based on the wave_HDPIs decided
And the optimal pressing force P of the pressure pulse wave sensor 46_HDPMaintain
The pressure regulating valve 52 is controlled in such a manner. The electrocardiograph 60 is provided at a predetermined site in a living body.
Myocardial action potential via a plurality of electrodes 62 attached
The continuous detection of the so-called ECG
And a signal indicating the electrocardiographic lead waveform is electronically controlled.
Supply to device 28. The upper waveform in FIG.
5 shows an example of an electrocardiographic lead waveform detected by the device 60.
You. FIG. 4 shows an electronic device in the blood pressure monitoring device 8.
Functional block for explaining a main part of a control function of control device 28
FIG. In the figure, the blood pressure measuring means 70
During the gradual change process of the compression pressure of 0, the pressure of the cuff 10
Based on the change of amplitude of cuff pulse wave obtained as force oscillation
The BP of the patient is determined by the oscillometric method._SYSYou
And diastolic blood pressure BP_DIAIs measured. Pressure pulse wave sensor 46
From the site where the patient's cuff 10 is to be worn, for example, from the upper arm
Is also pressed by the downstream part of the artery, such as the wrist.
To detect pressure pulse waves generated from the radial artery of the wrist.
You. The pressure pulse wave blood pressure correspondence relation determining means 72 includes a pressure pulse wave sensor
The magnitude P of the pressure pulse wave detected by 46_MAnd blood pressure measurement hand
The correspondence between the blood pressure value BP measured by step 70 and
Predetermined for a given patient. This correspondence is
For example, as shown in FIG. 3, BP = A · P_M+ B type
Is represented by Here, A is a constant indicating the slope, and B is the intercept.
It is a constant shown. Further, the monitoring blood pressure value determining means 74
Of the pressure pulse wave detected by the pressure pulse wave sensor 46 from the
Size P_MThat is, the highest value (upper peak value) P_Mmaxand
Minimum value (lower peak value) P_MminBlood pressure value MB based on
P_SYSAnd diastolic blood pressure MBP_DIA(Monitor blood pressure value)
It is determined sequentially, and the determined monitoring blood pressure value MBP is displayed on the display.
Output continuously. The cuff pressure increasing means 75 has the above relationship.
Activated at a predetermined cycle for calibration
During the measurement period of the blood pressure measurement means 70, the cuff 10
Change the compression pressure according to well-known measuring means
You. For example, the cuff pressure increasing means 75 determines the systolic blood pressure of the patient.
The boost target value set at about 180 mmHg, which is higher
After raising the cuff 10 with
Speed of about 3mmHg / sec in the measurement section to be executed
Gently lowers the blood pressure.
Release the pressure. Further, the phase difference calculating means 76 calculates the pressure pulse wave
The pressure pulse wave detected by the sensor 46 and the electrocardiographic lead
Phase between the ECG waveform detected by device 60
The difference Td is sequentially calculated. Here, the phase difference Td is shown in FIG.
The differential waveform of the pressure pulse wave from the R wave of the ECG lead waveform
Is calculated from the time difference up to the point at which the peak value is shown. Ki
The moving means 82 includes the phase difference reciprocal change value calculating means 78 and the monitored blood.
And a pressure value change value calculating means 80. That is, the rank
The phase difference reciprocal change value calculating means 78 is provided to the phase difference calculating means 76.
Accordingly, the reciprocal Td of the calculated phase difference Td^-1Change value ΔT
d^-1Are sequentially calculated. Where the change value ΔTd^-1as,
Moving average value Td^-1 _AV[= Td^-1 _in+ ... + Td^-1
_il+ Td^-1 _i/ (N + 1)] [= (T
d^-1-Td ^-1 _AV) / Td^-1 _AV] Is used. The monitoring blood pressure value change value calculating means 80
Systolic blood pressure determined by the monitoring blood pressure value determining means 74
Value MBP_SYSChange value ΔMBP_SYSAre sequentially calculated. This
Where the change value ΔMBP_SYSAs the moving average (MBP
_SYS)_AV[= (MBP_SYS) _in+ ... + (MBP
_SYS)_il+ (MBP_SYS)_i/ (N + 1)]
Rate of change ｛= [MBP_SYS− (MBP_SYS)_AV] / (MB
P_SYS)_AV｝ Is used. Then, the activation means 82
The phase calculated by the phase difference reciprocal change value calculating means 78
Change value ΔTd of reciprocal of difference and monitor blood pressure value change value calculating means
Systolic blood pressure value MBP calculated by 80_SYSChange value of
ΔMBP_SYSComparison value C with_DMIs calculated, and the comparison value C_DM
Exceeds a predetermined criterion value α.
Blood pressure measurement using the cuff 10 by the blood pressure measurement means 70
Activate the action. Where the comparison value C _DMAs ΔTd
^-1And ΔMBP_SYS| ΔTd^-1−ΔMBP_SYS｜,
Or the ratio | ΔTd^-1/ ΔMBP_SYS| Is used. FIG. 5 is an electronic view of the blood pressure monitoring device 8 of the present embodiment.
Flowchart illustrating a main part of control operation of control device 28
It is. In the figure, step SA1 (hereinafter referred to as step
Omit the step. ), The pressure in the pressure chamber 48 is gradually increased.
In the process of gradually increasing the pressure in the pressure chamber 48, the pressure pulse wave sensor 4
The pressure at which the amplitude of the pressure pulse wave sequentially detected by Step 6 becomes the maximum
The pressure in the chamber 48, that is, the optimal pressing force of the pressure pulse wave sensor 46
P_HDPIs determined, and the pressure in the pressure chamber 48 is reduced.
Optimal pressing force P_HDPThe pressure pulse wave
The pressing force of the sensor 46 is held at an optimum constant value. Subsequently, a function corresponding to the blood pressure measuring means 70 will be described.
At SA2, the blood pressure measurement algorithm is executed.
You. That is, the switching valve 16 is switched to the pressure supply state,
Activate the air pump 18 to reduce the pressure in the cuff 10.
Target pressure higher than the patient's expected systolic blood pressure value (eg,
After elevating the pressure to 180 mmHg), the air pump 18
Is stopped, and the switching valve 16 is switched to the slow exhaust pressure state.
Pressure in the cuff 10 to a predetermined 3 mmHg / se
By lowering at a gentle speed of about c,
Pulse wave signal SM sequentially obtained during the rapid step-down process₁Of the pulse wave
Well-known oscillometrics based on amplitude changes
Blood pressure value BP according to the blood pressure value determination algorithm
_SYS, Mean blood pressure BP_MEAN, And diastolic blood pressure BP_DIA
Is measured and the pulse rate is determined based on the cuff pulse interval.
Is determined. And the measured blood
The pressure value and the pulse rate are displayed on the display 32 and
Then, the switching valve 16 is switched to the rapid exhaust pressure state and the cuff 1 is released.
The pressure within 0 is rapidly exhausted. Subsequently, the pressure pulse wave blood pressure correspondence relation determining means is provided.
In SA3 corresponding to 72, the pressure from the pressure pulse wave sensor 46
Pulse wave magnitude (absolute value, ie pressure pulse wave signal SM_TwoThe size of
C) and blood from the cuff 10 measured in SA2 above.
Pressure value BP_SYS, BP_DIAAnd a correspondence between
You. That is, the pressure pulse wave from the pressure pulse wave sensor 46 reads one beat.
And the highest value P of the pressure pulse wave_MmaxAnd lowest
P_MminIs determined, and the maximum value P of the pressure pulse waves is determined.
_MmaxAnd the lowest value P_MminAnd measured by cuff 10 at SA2
Determined systolic blood pressure BP_SYSAnd diastolic blood pressure BP_DIA
And the magnitude P of the pressure pulse wave shown in FIG._MAnd blood pressure
Is determined. Then, in SA4, one pressure pulse wave is
It is determined whether the input has been made. No judgment of SA4
If set, wait until one pressure pulse wave is input.
However, if the determination in SA4 is affirmed,
SA5 and SA6 corresponding to monitoring blood pressure value determining means 74
At the optimum pressing force P_HDPPressure pulse wave sensor in Japan
The maximum value P of the pressure pulse wave from 46_Mmax(Upper peak value) and
Minimum value P_Mmin(Lower peak value) is determined
Is the pressure pulse wave blood pressure correspondence shown in FIG.
The maximum value P of the pressure pulse wave_MmaxAnd the lowest value P_MminBased on
Blood pressure MBP_SYSAnd diastolic blood pressure MBP
_DIA(Monitor blood pressure value) is determined and
The displayed monitor blood pressure value is displayed on the display 3 together with the continuous waveform of the pressure pulse wave.
2 is displayed. Subsequently, the monitoring blood pressure value change value calculating means 80
In corresponding SA7, the systolic blood pressure value MBP_SYSof
Change value ΔMBP_SYSIs calculated. Ie, systolic blood pressure
Value MBP_SYSMoving average (MBP_SYS)_AV[= (MB
P_SYS)_in+ ... + (MBP_SYS)_il+ (MBP
_SYS)_i/ (N + 1)] = [MBP
_SYS− (MBP_SYS)_AV] / (MBP_SYS)_AV算出 is calculated
Is done. Then, in SA8, one electrocardiographic lead
It is determined whether a waveform has been input. This SA8 format
If the disconnection is denied, one ECG waveform is input.
Until it is determined that SA8 has been affirmed.
In this case, the SA9 corresponding to the phase difference
And the phase difference Td between the pressure pulse wave and the electrocardiographic lead waveform is calculated.
You. Where the phase difference T_dIs as shown in FIG.
When the differential waveform of the pressure pulse wave from the guided R wave shows a peak value
It is calculated from the time difference to the point. Next, the phase difference
In SA10 corresponding to the conversion value calculation means 78,
Reciprocal Td of phase difference Td^-1Change value ΔTd^-1Is calculated
You. That is, the reciprocal of the phase difference Td^-1Moving average value of Td^-1
_AV[= Td^-1 _in+ ... + Td^-1 _il+ Td^-1 _i/
(N + 1)] [= (Td^-1-Td^-1 _AV)
/ Td^-1 _AV] Is calculated. Subsequently, SA11 corresponding to the starting means 82
, The reciprocal Td of the phase difference ^-1Change value ΔTd^-1
And the systolic blood pressure value MBP_SYSChange value ΔMBP_SYSWhen
Comparison value C_DMIs ΔTd^-1And ΔMBP_SYS| ΔT
d^-1−ΔMBP_SYS| Or ratio | ΔTd^-1/ ΔMBP
_SYS| And its comparison value C_DMIs preset
It is determined whether or not the determined reference value α has been exceeded. This judgment
The reference value α is a problem in monitoring patient's blood pressure
Experimentally to determine whether it has changed
It is what was sought. If this decision is affirmed,
Since the reliability of the monitoring blood pressure value MBP is considerably doubted,
SA2 and below are executed again to re-determine the correspondence
Is done. However, if this judgment is denied,
SA12 is executed because the pressure value MBP is reliable.
You. In SA12, the cuff 1 in SA2 is used.
Preset time elapsed since blood pressure measurement was performed by 0
The set cycle of about 30 minutes
It is determined whether the power cycle has elapsed. This SA12
If the judgment is denied, the blood pressure monitoring
Routine is repeatedly executed, the systolic blood pressure value MBP_SYSAnd
And diastolic blood pressure MBP_DIAIs determined continuously for each beat and
Are displayed. However, if this decision is affirmed,
In order to re-determine the correspondence, SA2 and below are again
Be executed. As described above, according to this embodiment, SA8
Electrocardiography in the living body by the electrocardiograph 60
The waveform is detected, and the pressure pulse wave sensor 46 detects the waveform in SA4.
When a pressure pulse wave generated from the living artery is detected,
The phase difference Td between the ECG waveform and the pressure pulse wave is calculated by the phase difference calculation method.
The phase difference reciprocal calculated in SA9 corresponding to the stage 76
The phase difference in SA10 corresponding to the change value calculating means 78
Reciprocal Td of^-1Change value ΔTd^-1Is calculated. In addition, supervisor
In SA6 corresponding to the visual blood pressure value determining means 74, the pressure
When the monitored blood pressure value MBP is determined based on the pulse wave,
Systolic blood pressure value MBP in blood pressure value MBP_SYSChange value Δ
MBP_SYSCorresponds to the monitoring blood pressure value change value calculating means 80.
Is calculated in SA7. And the phase difference
Reciprocal Td ^-1Change value ΔTd^-1And systolic blood pressure MBP_SYSof
Change value ΔMBP_SYSComparison value C with _DM, For example, the difference between the two
Or, when the ratio exceeds the predetermined judgment reference value α.
On the basis of this, the start-up means 82
The blood pressure measurement operation using the cuff 10 is started.
Therefore, the reciprocal T of the phase difference between the electrocardiographic lead waveform and the pressure pulse wave
d^-1The change tendency of the monitoring blood pressure value MBP is
To the already experimentally found findings that there is an example relationship
Based on the reciprocal of the phase difference Td^-1Change value ΔTd^-1And monitoring
Systolic blood pressure value MBP in blood pressure value MBP_SYSChange value Δ
MBP_SYSComparison value C with_DMIs a preset criterion value
If α or more, that is, the reciprocal of the phase difference Td^-1Strange
And the tendency of change in the monitored blood pressure value MBP have a proportional relationship.
And the reliability of the monitored blood pressure value MBP is suspected.
The blood pressure measurement operation using the cuff 10 is started.
Therefore, the cuff 10 for re-determining the correspondence is used.
Blood pressure measurement cycle can be set to a relatively long time
And the frequency of blood pressure measurement using the cuff 10 is reduced.
The burden on the living body is reduced, and the blood pressure monitoring
Continuity is improved as much as possible. Further, according to the present embodiment, the SA 12 is provided.
Has passed through a predetermined calibration cycle.
Every time the pressure pulse wave and the monitored blood pressure value MBP
Are determined again, the pressure pulse wave sensor 46
The monitoring blood pressure value MBP measured by
Be held. An embodiment of the present invention will now be described with reference to the drawings.
Although described, the invention is applicable in other aspects.
You. For example, in the above-described embodiment, the phase difference
Reciprocal Td^-1Is the differential wave of the pressure pulse wave from the R wave of the ECG lead waveform
Calculated based on the time difference Td until the shape shows the peak value
However, the time difference Td is equal to R of the electrocardiographic lead waveform.
Time difference from the time when the pressure pulse wave shows the maximum value to the wave, or
From the R wave of the ECG lead waveform to the time when the pressure pulse wave shows the minimum value
Can be variously defined. In short, the time difference
Td is a pressure pulse wave from a predetermined point in the electrocardiographic lead waveform.
Is calculated based on the time difference up to a predetermined point in
I just need to. In the above embodiment, the monitored blood pressure value
When calculating the change value ΔMBP of MBP, the monitor blood pressure value M
BP is the systolic blood pressure value MB in the monitored blood pressure value MBP
P_{SY S}Was calculated based on the monitoring blood pressure value MBP
Blood pressure value ΔMBP in rats _DIAIs calculated based on
It may be. In short, based on the predetermined monitoring blood pressure value MBP
It suffices if it is calculated. In the above-described embodiment, the phase difference is reversed.
Number Td^-1Change value ΔTd^-1When calculating or monitoring
When calculating the change value ΔMBP of the blood pressure value MBP,
Reciprocal Td of each phase difference^-1Of the moving average relative to its moving average
Rate or monitoring blood pressure value MBP to its moving average
, The reciprocal of the phase difference T
d^-1Rate of change of the regression line, or monitored blood pressure
The rate of change of the value MBP with respect to the regression line is used.
You may. In short, the reciprocal of the phase difference Td^-1And monitor blood pressure values
A method that can accurately grasp the rate of MBP change
It just needs to be done. In the above-described embodiment, the SA12
Is provided, a predetermined calibration cycle
The correspondence relationship was re-determined every period.
If SA11 is denied without A12
In the case, SA4 and below are configured to be repeated
Is also good. In this way, the pressure pulse wave sensor 46 measures
Only when the determined monitoring blood pressure value MBP is suspicious,
Blood pressure measurement using cuff 10 to re-determine correspondence
Is performed, the burden on the patient is further reduced, and
Further, the continuity of blood pressure monitoring is further improved. In addition, the present invention does not depart from its gist.
Various changes can be made in the boxes.

BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a block diagram illustrating a configuration of a blood pressure monitoring device 8 according to an embodiment of the present invention. FIG. 2 is a diagram exemplifying a pressure pulse wave detected by a pressure pulse wave sensor 46 and an electrocardiographic lead waveform detected by an electrocardiographic lead device 60 in the embodiment of FIG. FIG. 3 shows the magnitude P of the pressure pulse wave used in the present embodiment.
It is a figure which illustrates the correspondence of _M and monitoring blood pressure value MBP. FIG. 4 is a functional block diagram for explaining a main part of a control function of the electronic control device of the embodiment of FIG. 1; FIG. 5 is a flowchart for explaining a main part of a control operation of the electronic control device of the embodiment of FIG. 1; [Description of Signs] 10: Cuff 46: Pressure pulse wave sensor 60: Electrocardiograph 70: Blood pressure measurement means 72: Pressure pulse wave blood pressure correspondence relation determination means 74: Monitoring blood pressure value determination means 75: Cuff pressure increasing means 76: Phase difference calculating means 82: starting means

──────────────────────────────────────────────────続 き Continuation of the front page (56) References JP-A-4-200439 (JP, A) JP-A-5-146415 (JP, A) JP-A-6-319706 (JP, A) JP-A-6-319706 38933 (JP, A) JP-A-7-136136 (JP, A) JP-A-7-313472 (JP, A) JP-T3-505533 (JP, A) Patent 2664918 (JP, B2) (58) Survey Field (Int.Cl. ⁷ , DB name) A61B 5/022 A61B 5/0245

Claims (1)

(57) [Claims 1] A compression pressure of a cuff attached to a living body is changed, and a blood pressure value of the living body is measured based on a change of a pulse synchronizing wave generated in a process of changing the compression pressure. Blood pressure measuring means, a pressure pulse wave sensor for detecting a pressure pulse wave generated from the artery when pressed by the artery of the living body, and the pressure pulse wave sensor by activating the blood pressure measuring means at a predetermined cycle. A pressure pulse wave blood pressure correspondence relationship determining means for determining a pressure pulse wave blood pressure correspondence relationship between the magnitude of the pressure pulse wave detected by the blood pressure measurement means and the pressure pulse wave blood pressure value, A monitoring blood pressure value determining means for sequentially determining a monitoring blood pressure value based on an actual pressure pulse wave, comprising: an electrocardiographic lead device that detects an electrocardiographic lead waveform of the living body; With the pressure pulse wave detected by the wave sensor A phase difference calculating means for calculating a phase difference between the detected ECG waveform by said cardiac induction device, and the change value of the reciprocal of the phase difference calculated by the phase difference calculating means, the monitoring blood pressure determining means The comparison value with the change value of the monitoring blood pressure value determined according to the predetermined criterion
A blood pressure monitoring device comprising: a start-up unit that starts a blood pressure measurement operation by the blood pressure measurement unit to re-determine the pressure pulse wave blood pressure correspondence relationship based on the value being exceeded .