JP3297685B2 - Flexible intraocular lens - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a soft intraocular lens, and more particularly to a soft intraocular lens capable of suppressing deformation of a soft optic portion caused by contraction of a capsule after insertion into an eye.

[0002]

2. Description of the Related Art An intraocular lens is composed of an optical part functioning as a substitute lens for a crystalline lens removed by a cataract, and an elongated arm-shaped support part for fixing and holding the optical part at a central position in a capsule. Be composed. Conventionally, this intraocular lens, the type which is adapted to join the the support portion optic later this separately manufactured as a separate part, respectively (also referred to as Tsuupisu or Suripi over Stipe), an optical unit There is known an integrated type (also referred to as a one-piece type) in which a support portion is integrally formed from the beginning.

In the above-mentioned two-piece or three-piece type intraocular lens, the optical part is made of a hard material, PMMA (polymethyl methacrylate), and a PMM is used as a supporting part for fixing and holding the PMMA optical part.
It is common to use monofilaments such as A, PP (polypropylene), and polyimide. For joining the optical part and the support part, a small hole is mechanically provided in the optical part, and the support part is inserted into the small hole and fixed by staking or fusion by laser irradiation. At the time of fixing, the support part is 5 degrees or 1 degree with respect to a plane orthogonal to the optical axis of the optical part.
In many cases, the angle is set to form an angle of 0 degrees. This is to ensure stable positioning after the lens is settled in the capsule. In addition, PMMA
Is used because it is excellent in transparency, machinability, and stability in the body.

The above-mentioned one-piece type (integrated type) intraocular lens often has an optical part and a support part integrally formed of PMMA. FIG. 6 is a plan view of a conventional integrated intraocular lens, and FIG. 7 is a diagram showing an image of a shape of a support portion of the conventional integrated intraocular lens viewed from a side direction. In these figures, reference numeral 10 denotes an optical unit, and reference numeral 20 denotes a support unit. As shown in the image diagram of FIG. 7, the shape of the support portion of this type of intraocular lens often has an angle of 5 degrees or 10 degrees similarly to the two-piece or three-piece type intraocular lens.

Further, as a shape of the supporting portion, there is a so-called wing type. FIG. 8 is a diagram showing an image of the shape of the support portion from the side direction of the wing type. This type of support 20 has a support 5 degrees or 10 degrees.
It rises at an angle of degrees and becomes almost parallel to a plane orthogonal to the optical axis of the optical unit from the middle. Both types of supports are designed such that the lens inserted into the capsule is stably fixed within the capsule.

In recent years, with the spread of ultrasonic emulsification suction, an intraocular lens that can be inserted from a small incision for the purpose of reducing postoperative astigmatism and invasiveness of surgery has been developed. That is, a soft intraocular lens in which a soft material is used as a material constituting the optical unit, whereby the optical unit is bent to enable insertion from a small incision. Regarding the design of the support portion in this soft intraocular lens, the angle is set to 5 degrees or 10 degrees as described above.
A type having a certain angle or a wing type is known.

[0007]

When the intraocular lens is inserted into the capsule, the inside diameter of the capsule shrinks to about 10 mm. The support is compressed accordingly. Generally, the optical section is supported by the action of elastic force generated by compression of the support section. At this time, a part of the elastic force is transmitted to the optical unit. When the optical part is formed of a hard material such as PMMA, there is almost no problem caused by the transmission of the elastic force. However, when the optical unit is made of a soft material, depending on the manner of insertion into the capsule, when the elastic force is transmitted to the optical unit, the optical unit may be deformed or distorted by the force,
Alternatively, it is impossible to deny the possibility that the resolving power and power as designed do not come out because the amount of deviation of the lens does not become constant. The present invention has been made under the above-described background, and a soft intraocular lens having a low possibility that the optical unit is deformed or distorted even if the sac contracts and the support portion is compressed after insertion into the sac. The purpose is to provide.

[0008]

As means for solving the above-mentioned problems, a first means is an optical part made of a deformable soft material, and is extended outward from an outer peripheral part of the optical part. An arm-shaped support that fixes the optical part in the eye
And a supporting portion for holding the soft intraocular lens, wherein a force is applied to compress the supporting portion from outside so that at least any part of the supporting portion moves toward the optical portion. Sometimes at least part of the force is absorbed by deformation and the optical part is moved in a direction parallel to its optical axis.
Before so as to be able to reduce the force to move
A soft intraocular lens characterized in that two bent portions bent in a direction parallel to the optical axis are provided on a support portion.

[0009] A second means is the soft intraocular lens according to the first means , wherein the supporting portion is located on a plane orthogonal to the optical axis of the optical portion as going outward from a root near the optical portion. The bent portion is formed so as to form a first angle with respect to the first angle, and the bent portion has a first angle with respect to a plane orthogonal to the optical axis of the optical portion at a position outside the root of the support portion. A first bent portion bent to form an opposite second angle, and the second bent portion with respect to a plane perpendicular to the optical axis of the optical portion at a position outside the first bent portion. And a second bent portion bent so as to form a third angle opposite to the angle.

The third means is a soft intraocular lens according to the second means , wherein the first angle is 12 ° or less.

[0011] The fourth means may be the second or the third means.
In that soft intraocular lens, the distance from the root portion of the support portion to the first bent portion is a soft intraocular lens, characterized in that is within 3 mm.

The fifth means is any one of the first to fourth hands.
In the soft intraocular lens according to the step, the soft intraocular lens is an integral type in which the optical unit and the support unit are integrally formed.

The sixth means is any one of the first to fifth hands.
In the soft intraocular lens according to the step, the support portion is made of a material that is harder than a soft material that forms the optical portion.

[0014]

[0015]

(Embodiment 1) FIG. 1 is a view showing a configuration of a soft intraocular lens according to Embodiment 1 of the present invention, and FIG. 1 (a) is a plan view thereof and FIG. ) Is a side view thereof, and FIG. 2 is a partially enlarged view of FIG.

In FIG. 1, this soft intraocular lens has an optical part 1 and two arm-shaped support parts 2 extending outward from the outer peripheral part of the optical part 1 to be integrally formed. It is a body-shaped soft intraocular lens.

The optical section 1 is a circular convex lens made of a flexible optical member described later, and has an outer diameter of about 5.0 to 6.5 m.
mφ.

The support portion 2 is made of PMMA 2 extending outward from two portions which are the outer peripheral portion of the optical portion 1 and have a point symmetry with respect to the center O of the optical portion 1.
It is an arm of a book. As shown in FIG. 1A, the shape of the support portion 2 in a plan view is such that the rate of moving away from the optical portion from the root portion 22 near the boundary with the optical portion 1 decreases, and In the vicinity of the section, the optical section 1 has a curved shape that is substantially concentric with the optical section 1.

As shown in FIG. 1B and FIG. 2, the shape of the support portion 2 in a side view is perpendicular to the optical axis of the optical portion 1 from the base 21a of the root portion 21 toward the outside. The base 2 is formed so as to form a _first angle α _1.
The first bent portion 22 is formed at a distance a from the first bent portion 1a, and the second bent portion 23 is positioned at a distance b with respect to a tangent at a portion which is substantially concentric with the optical portion 1 near the tip.
Is formed. A portion located outside the second bent portion 23 is formed so as to be substantially parallel to a plane orthogonal to the optical axis.

The distance a is set within 3 mm. In this embodiment, it is 1 mm. Angle alpha ₁ is set within 12 °. In this embodiment, α _{1 is set} to about 5 °. The distance b is set within several mm. In this embodiment, the distance b is 1.5
mm. The angle of the first bent portion 22 is set so that the portion between the first bent portion 22 and the second bent portion 23 forms an angle α ₂ with a plane parallel to the optical axis. Is set to The bending angle of the second bent portion is the second bent portion 2
The angle is set such that a portion located outside of 3 is substantially parallel to a plane orthogonal to the optical axis. Here, if an angle between a straight line connecting the tip of the support portion 2 and the outer peripheral end of the optical portion 1 with a plane orthogonal to the optical axis is β, the above α
₂ is set so that this β is about 5 °. In this embodiment, α ₂ is about 17 °.

The integrated soft intraocular lens having the above structure is
It was manufactured as follows. That is, an annular body 200 having a through-hole of about 6.5 mmφ was formed at the center of a button material (diameter of about 16.5 mmφ) formed of a substantially disc-shaped PMMA. Next, the through-hole of the annular body 200 was filled with a monomer mixture having the following composition , and a nitrogen pressure of 19.6 × 10 4
Pressure polymerization at Pa (2.0 Kgf / cm ² ) at a temperature of 60 ° C. for 2 hours is performed, and thereafter, holding at 80 ° C. for 2 hours, 100
C. for 2 hours to complete the polymerization. As a result, the through-hole at the center of the annular body 200 of PMMA was completely closed and joined by the flexible optical member 100, and the disc-shaped lens material 300 in which these were integrated was obtained. FIG. 3 is a perspective view of the lens material 300, and FIG. 4 is a sectional view of the lens material 300.

Parts by weight n-butyl acrylate 42 2- phenylethyl methacrylate 49 2- [2- (perfluorooctyl) ethoxy] -1-methylethyl methacrylate 9 ethylene glycol dimethacrylate 3 azobisisobutyro Nitrile 0.3

Next, the lens material 300 is set at -10.degree.
After the cutting for forming the optical surface was performed while blowing the cold air, a process of cutting out a one-piece shape from the button by milling was performed to form a predetermined lens shape and a supporting portion shape. FIG. 5 is a diagram showing a state where the lens material 300 is cut by the milling 400. The thus-processed product was barrel-polished for 5 days to obtain an integrated soft intraocular lens according to Example 1.

[0024] (Example 2) and about 10 ° the angle of alpha ₁ in Example 1, about an angle of alpha ₂ along with this 29
The same configuration as in the first embodiment except for the angle of
And

Comparative Example 1 Comparative Example 1 was the same as that of Example 1 except that the shape of the support portion was the conventional type shown in FIG. 7 and α = 5 °.

Comparative Example 2 Comparative Example 2 was the same as that of Example 1 except that the shape of the support portion was the conventional wing type shown in FIG. 8 and α = 10 °.

(Comparative Example 3) PM for both the optical part and the support part
A comparative example 3 was a conventional integrated intraocular lens integrally formed of MA and having a support portion having a conventional shape shown in FIG.

Comparative Example 4 was the same as Comparative Example 3 except that the shape of the supporting portion was the conventional wing type shown in FIG. 8 and α = 10 °.

Examples 1 and 2 and Comparative Examples 1 to
For No. 4, the following test was performed. (1) Resolution / Power Test This test is a test in which each lens is fixed in a ring having an inner diameter of 10 mmφ, and the resolution and power (frequency) are measured.

The results of the resolving power / power test are shown in Examples 1 and 2.
2 and Comparative Examples 3 and 4 were fit in a 10 mmφ ring, and it was confirmed that both the resolving power and the power maintained the values as designed. However, in Comparative Examples 1 and 2, after the 10 mmφ ring was fixed, the optical portion gradually floated up, and the optical portion was deformed. therefore,
In the ring of 10 mmφ, the resolution and power of the lenses of Comparative Examples 1 and 2 could not be measured.

(2) Compression vaulting test In this test, as shown in FIG. 9, the lens 3 or 30 was set in the holding diameter variable jig 50, and the holding diameter of the variable holding diameter jig 50 was 11 mmφ. And 10mmφ,
At that time, the distance that the center of the optical unit 1 moves in the optical axis direction is measured by a digital measuring microscope (STM5-3 manufactured by Olympus Corporation).
This is a test measured in 22).

The result of the vaulting test by compression is:
It was as shown in FIG. As is clear from FIG. 10, Examples 1 and 2 are conventional PMMA integrated types (the optical part is also composed of PMMA = hard material) and the type shown in FIG. 7 (α = 5 °) and FIG. Wing type indicated (α
= 10 °) (comparative examples 3 and 4)
It can be seen that there is almost no difference at the time of compression of both mφ and 10 mmφ, which is extremely good.

However, the optical part is made of a soft material, the supporting part has the structure shown in FIG. 7 (α = 5 °) and the supporting part has the wing type shown in FIG. 8 (α = 10 °).
°), that is, in the case of Comparative Examples 1 and 2, the optical part greatly moved in the direction of the optical axis when compressed by 10 mmφ, and was deformed.

It is presumed that the above results are obtained due to the following effects. That is, in the conventional type shown in FIG. 7, as shown in FIG. 11A, when the support portion is compressed, the compressive force is transmitted in the longitudinal direction of the support portion as it is to the optical portion, and the optical portion is compressed. Is pushed up or deformed in the optical axis direction.

In the conventional wing type shown in FIG. 8, as shown in FIG. 11 (b), the compression force is dispersed once when the support portion is compressed, but the compression force is insufficient due to insufficient dispersion. It is considered that a considerable portion of the force is transmitted to the optical unit, and pushes up or deforms the optical unit in the optical axis direction.

On the other hand, in the embodiment of the present invention,
As shown in FIG. 11C, since the compressive force is dispersed twice before reaching the optical unit, it is considered that the force applied to the optical unit is appropriately attenuated.

[0037]

As described above in detail, the present invention is applicable to a case where a force is applied to compress the support from the outside so that at least any part of the support moves toward the optical unit. A bent portion capable of absorbing at least a part of the compressive force by deformation to reduce a force transmitted to the optical portion is provided on the support portion, whereby the capsule is contracted after insertion into the capsule. As a result, a flexible intraocular lens is obtained in which the optical section is less likely to be deformed or distorted even if the support section is compressed.

[Brief description of the drawings]

FIG. 1 is a diagram showing a configuration of a soft intraocular lens according to Example 1 of the present invention, wherein FIG. 1 (a) is a plan view and FIG. 1 (b) is a side view.

FIG. 2 is a partially enlarged view of FIG. 1 (b).

FIG. 3 is a perspective view of a lens material.

FIG. 4 is a sectional view of a lens material.

FIG. 5 is a diagram showing a state of processing a lens material.

FIG. 6 is a plan view of a conventional integrated intraocular lens.

FIG. 7 is a view showing an image of a shape of a support portion of a conventional integrated intraocular lens as viewed from the side.

FIG. 8 is a view showing an image of a shape of a support portion from a side direction of a wing type.

FIG. 9 is a view showing a state of a vaulting test by compression.

FIG. 10 is a diagram showing a result of a vaulting test by compression.

FIG. 11 is an operation explanatory view of an example and a comparative example.

[Explanation of symbols]

 1, 10 optical part 2, 20 support part 3, 30 intraocular lens 21 root part 22 first bent part 23 second bent part

──────────────────────────────────────────────────続 き Continued on the front page (58) Field surveyed (Int. Cl. ⁷ , DB name) A61F 2/16 A61L 27/00 WPI (DIALOG)

Claims (6)

(57) [Claims] 1. An optical part made of a deformable soft material,
A flexible intraocular lens having an arm-shaped support portion extending outward from the outer peripheral portion of the optical portion and fixing and holding the optical portion in the eye, wherein at least the support portion When a force for compressing the support portion from outside is applied so that any portion moves toward the optical portion, at least a part of the force is absorbed by deformation and the optical portion is moved along its optical axis. Moved in a direction parallel to
So that the optical axis can be reduced.
A flexible intraocular lens characterized in that two bent portions bent in a direction parallel to the direction are provided on the support portion. 2. The soft intraocular lens according to claim 1 , wherein the supporting portion is arranged on a first surface with respect to a plane perpendicular to an optical axis of the optical portion as going outward from a root near the optical portion. The bent portion is formed at a position outside the root portion of the support portion with respect to a plane orthogonal to the optical axis of the optical portion at a position outside the first portion.
A first bent portion bent to form a second angle opposite to the angle of the first bent portion, and a position outside the first bent portion with respect to a plane orthogonal to the optical axis of the optical portion. Second
A second bent portion bent so as to form a third angle opposite to the angle of the soft intraocular lens. 3. The soft intraocular lens according to claim 2 , wherein the first angle is 12 ° or less. 4. The flexible intraocular lens according to claim 2 , wherein a distance from a root of the support to the first bent portion is three.
A soft intraocular lens, which is within mm. 5. The soft intraocular lens according to claim 1 , wherein the soft intraocular lens is an integral type in which the optical section and the support section are integrally formed. Flexible intraocular lens. 6. The soft intraocular lens according to claim 1, wherein the support portion is made of a material that is harder than a soft material that forms the optical portion. Soft intraocular lens.