JP3233682B2 - Medical liquid treatment equipment - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a medical liquid processing apparatus having a high processing liquid discharge efficiency.

[0002]

2. Description of the Related Art In the medical field, a medical liquid processing apparatus represented by a heat exchanger for maintaining a patient's blood at a constant temperature or for cooling or reheating is mainly used at the time of surgery, It is used when connecting an artificial lung to a patient.

Conventionally, as this type of medical liquid processing apparatus, a large number of small tubes and a space between the small tubes and the housing are provided.
Generally, blood and a heat exchange medium are respectively circulated to exchange heat between the two liquids.For example, blood exchanged through the tubule is heat-exchanged in a housing of a medical liquid treatment apparatus. The liquid is collected in a processing liquid discharge chamber disposed on the side, and is discharged to the outside through a processing liquid discharge port from an opening formed in the processing liquid discharge chamber.

[0004] As a treatment liquid discharge port in a conventional medical liquid treatment apparatus, one having a structure shown in FIGS. 4 and 5 is mainly used.

That is, in FIG. 4, a housing 2 of a medical liquid processing apparatus 1 has a processing liquid discharge chamber 3 on its side.
An opening 4 is formed in an upper portion of the processing liquid discharge chamber 3, and a processing liquid discharge port 5 communicating with the opening 4 is disposed vertically downward of the housing 2.

Therefore, the processing liquid (for example, blood) introduced into the housing 2 from the processing liquid inflow port 6 is processed (for example, heat exchange) by the liquid processing mechanism inside the housing 2, and is transferred to the processing liquid discharge chamber 3. The liquid is collected, flows from the opening 4 to the processing liquid discharge port 5, and is discharged from the front end 5 a of the processing liquid discharge port 5.

However, in this conventional example, priming is performed by filling the processing liquid discharge chamber 3 and the processing liquid discharge port 5 from the inside of the housing 2 with, for example, a physiological saline solution, expelling air, and then flowing blood. During the process, stagnation of bubbles occurs due to stagnation just below the opening 4 in the processing liquid discharge port 5, and the processing liquid discharge port 5
Not only is the discharge efficiency of the liquid inferior, but also the residual liquid is wasted in the processing liquid discharge chamber 3 when the processing of the liquid is completed, and the residual liquid is wasted. It involved problems such as the need to perform cumbersome work.

The conventional example shown in FIG. 5 is an example in which an opening 4 is provided near the bottom of the processing liquid discharge chamber 3 and a processing liquid discharge port 5 is connected to this opening, so that the liquid processing is completed. This eliminates the problem that a residual liquid is generated in the processing liquid discharge port 5 after the processing.

However, in the conventional example shown in FIG. 5, although the residual liquid is eliminated, a large amount of bubbles are generated in the upper portion of the processing liquid discharge chamber 3 during priming, so that the conventional example shown in FIG. However, there is a problem that the processing liquid discharge efficiency from the processing liquid discharge port 5 is extremely inferior to that of

[0010]

SUMMARY OF THE INVENTION The present invention has been achieved as a result of study for solving the problems of the above-mentioned conventional medical liquid processing apparatus.

SUMMARY OF THE INVENTION Accordingly, an object of the present invention is to provide a medical liquid processing apparatus which eliminates residual liquid or bubbles and has a high processing liquid discharge efficiency.

[0012]

In order to achieve the above object, a medical liquid processing apparatus according to the present invention comprises a housing provided with a liquid processing mechanism therein, and a processing liquid disposed on a side of the housing. A medical liquid treatment apparatus comprising: a discharge chamber; a main opening formed in an upper portion of the processing liquid discharge chamber; and a processing liquid discharge port which is communicated with the main opening and is disposed vertically downward in the housing. Wherein a sub-opening having a smaller diameter than the main opening and communicating with the processing liquid discharge port is provided at a position near the bottom of the processing liquid discharge chamber (first invention).

Further, the medical liquid processing apparatus of the present invention comprises:
A housing provided with a liquid processing mechanism therein, a processing liquid discharge chamber disposed on a side of the housing, a main opening formed at an upper portion of the processing liquid discharge chamber, and a communication opening through the main opening; A medical liquid processing apparatus having a processing liquid discharge port disposed vertically downward of a housing, wherein the processing liquid discharge chamber is located below a lower end of the main opening and not exceeding a diameter of the main opening. A sub-opening having a smaller diameter than the main opening and communicating with the processing liquid discharge port is provided at a position (second invention).

[0014]

According to the first aspect of the present invention, there is provided a medical liquid treatment apparatus comprising:
Since the main opening is provided at the upper part of the processing liquid discharge chamber, air bubbles can escape, and not only the processing liquid discharge efficiency is improved, but also the position near the bottom of the processing liquid discharge chamber has a smaller diameter than the main opening. In addition, since the sub-opening communicating with the processing liquid discharge port is provided, the residual liquid can be discharged from the sub-opening. Can be eliminated.

In the medical liquid treatment apparatus according to the second aspect of the present invention, since the main opening is provided above the treatment liquid discharge chamber, air bubbles can escape, so that not only the treatment liquid discharge efficiency can be improved, but also the treatment liquid can be improved. From the lower end of the main opening of the liquid discharge chamber,
A sub-opening having a smaller diameter than the main opening and communicating with the processing liquid discharge port is located at a position below the diameter of the main opening, that is, at a portion where bubbles are most likely to be generated in the processing liquid discharge port. Is provided, air bubbles can escape from the sub-opening, and air bubbles generated during the convection of the processing liquid can be removed by the sub-opening. And the discharge efficiency of the processing liquid can be more effectively improved.

Accordingly, the medical liquid treatment apparatus of the present invention does not generate residual liquid or bubbles and has excellent drainage efficiency of the treatment liquid, so that it can be used for various operations or for connection to an artificial lung. It can be preferably applied to medical use.

[0017]

BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a block diagram of a medical liquid treatment apparatus according to an embodiment of the present invention.

FIG. 1 is a longitudinal sectional view showing a first embodiment of a medical liquid treatment apparatus according to the present invention, FIG. 2 is a longitudinal sectional view showing a second embodiment of the same, and FIG. It is a longitudinal cross-sectional view of a liquid discharge port part.

The first embodiment shown in FIG. 1 shows an example in which the medical liquid processing apparatus of the present invention is applied to a heat exchanger. This medical liquid processing apparatus has a cylinder having a liquid processing mechanism inside. , A processing liquid discharge chamber 20 disposed on a side of the housing 10, a main opening 21 formed in an upper portion of the processing liquid discharge chamber 20, and the main opening 21 communicating with the main opening 21. The processing liquid discharge port 22 is disposed substantially vertically downward of the housing 10.

The liquid treatment mechanism in the housing 10 is disposed in parallel with the first liquid inflow port 11 and the first liquid inflow port 12 provided to face the housing 10 in the radial direction and in the housing 10 in the axial direction. Plural second liquid circulation thin tubes 1
3, a second liquid introduction chamber 14 provided at the other end of the housing 10, an introduction port 15 for introducing the second liquid into the introduction chamber 14, and the second liquid introduction chamber 15 provided at both ends of the housing 10. The two liquid introduction chamber 14 and the discharge chamber (the processing liquid discharge chamber) 20 and the interior of the housing 10 are sealed in a liquid-tight manner, and the thin tube 13 and the second liquid introduction chamber 14 and the discharge chamber 20 are separated from each other. A seal portion 16 for allowing communication;
17.

As the shape of the housing 10, various shapes such as a cylindrical shape and a polygonal cylindrical shape are conceivable. However, the first liquid is formed in a cylindrical shape because the first liquid can flow in while being widely distributed from the periphery thereof. Is most preferred.

As a material used for forming the housing 10, a synthetic resin is generally used, and specific examples thereof include polycarbonate, acrylonitrile-styrene copolymer, acrylonitrile-butadiene-styrene copolymer and the like. .

The thin tube 13 is made of a metal tube having a high thermal conductivity, for example, a stainless steel tube, an aluminum tube, or the like, and has an inner diameter of 0.5 to 10 mm, preferably about 0.5 to 5 mm, and about 10 to 2000 tubes. Preferably about 50-1000
The book 10 is arranged in parallel with the axial direction of the housing 10.

The seal portions 16 and 17 are formed by curing a polymer potting agent such as polyurethane or silicone rubber.

The second liquid introduction chamber 14 and the discharge chamber 20 provided at both ends of the housing 10 are fitted with the partition wall 18 and the processing liquid discharge port 22 at both ends of the housing 10 via O-rings 19. Is formed.

In the medical liquid processing apparatus of the present invention having the above-described structure, the housing 10 is connected to the first liquid inlet 11 through the housing 10.
Heat exchange medium (eg, water)
The processing liquid (for example, blood) introduced from the liquid introduction port 15 is circulated from the introduction chamber 14 into the thin tube 13 to exchange heat with the first liquid, and the heat-exchanged processing liquid is further processed into the processing liquid discharge chamber. 20 and functions as a heat exchanger for discharging the processing liquid from the processing liquid discharge port 22.

The treatment liquid discharge port 22 has the following structure, thereby improving the treatment liquid discharge efficiency.

That is, the processing liquid discharge port 22 communicates with the main opening 21 formed at the top of the processing liquid discharge chamber 20 disposed on the side of the housing 10 and is disposed vertically downward of the housing 10. I have.

At a position near the bottom of the processing liquid discharge chamber 20, a sub-opening 23 having a smaller diameter than the main opening 21 and communicating with the processing liquid discharge port 22 is provided.

With this configuration, air bubbles can escape from the main opening 21 and the efficiency of discharging the processing liquid can be increased. In addition, the processing liquid accumulated in the processing liquid discharge chamber 20 from the sub-opening 23 can be improved. Can be completely discharged, and a problem that a residual liquid is left in the processing liquid discharge chamber 20 after the liquid processing is completed is effectively eliminated.

In the first embodiment, as shown, the pressure loss is reduced by reducing the thickness of the portion of the inner wall of the processing liquid discharge port 22 from the main opening 21 to the sub opening 23. By increasing the flow rate of the processing solution while keeping it to a minimum, bubbles can be more effectively released.

Although not shown, the diameter of the hole extending from the main opening 21 to the tip of the processing liquid discharge port may be increased in the inner wall of the processing liquid discharge port 22 instead of the above-described reduced diameter. In the same manner as described above, an effect of allowing bubbles to escape more effectively can be obtained by forming a taper on the surface.

Next, in the second embodiment shown in FIG. 2, the processing liquid discharge chamber 20 is moved from the lower end of the main opening 21 to the main opening 2.
The main opening 2 is located at a position below the diameter of the main opening 2.
The second embodiment is different from the first embodiment in that a sub-opening 24 having a diameter smaller than 1 and communicating with the processing liquid discharge port 22 is provided and communicating with the processing liquid discharge port 22. The structures of the housing 10 and the liquid processing mechanism are all the same as in the first embodiment.

In the second embodiment, the main opening 21
Air bubbles can escape from the processing solution, and not only the efficiency of discharging the processing solution can be enhanced, but also the bubbles generated during the stagnation of the processing solution can be removed by the sub-opening 24, so that the inside of the processing solution discharge port 20 can be removed. Can be suppressed, and the discharge efficiency of the processing liquid can be more effectively improved.

In the third embodiment shown in FIG. 3, both the sub-openings 23 and 24 having the above-described structure are formed in the processing liquid discharge chamber 20, and these sub-openings 23 and 2 are formed.
An example is shown in which the remaining liquids 4 are communicated with the processing liquid discharge port 22 to eliminate residual liquid and remove and suppress bubbles, thereby improving the processing liquid discharge efficiency more effectively.

Next, the effects of the medical liquid treatment apparatus of the present invention will be further described with reference to test examples.

[0037]

Test Example: A polycarbonate housing 10 having the structure shown in FIG. 1 having an inner volume of 450 ml, an inner diameter of a thin tube 13 made of a stainless steel tube disposed in the housing 10 is 0.84 mm, and the number of tubes arranged is about 850. Book, seal part 1
The medical liquid treatment apparatus of the present invention (Example 1) was manufactured with the constituent materials of Nos. 6 and 17: polyurethane, the inner diameter of the discharge port 22: 12.0 mm, and the inner diameter of the sub-opening 23: 3.0 mm.

The thickness of the portion from the main opening 21 to the sub-opening 23 of the inner wall of the processing liquid discharge port 22 should be at least 2.
By reducing the diameter by 0 mm, the medical liquid treatment apparatus of the present invention (Example 2) was manufactured.

In place of the sub-opening 23, at a position 5.0 mm below the lower end of the main opening 21, an inner diameter of 3.mm.
The medical liquid treatment apparatus of the present invention (Example 3) was manufactured by forming the sub-opening 24 of 0 mm and having the structure shown in FIG.

Further, the sub-openings 23 and 2 having the above configuration
4 was formed to have the structure shown in FIG. 3 to manufacture a medical liquid treatment apparatus (Example 4) of the present invention.

On the other hand, for comparison, under the same conditions as above, the medical liquid treatment apparatus having the conventional structure shown in FIG. 4 (Comparative Example 1) and the medical liquid treatment apparatus having the conventional structure shown in FIG. Comparative Example 2) was produced.

With respect to these six types of medical liquid treatment apparatuses, a heat exchange medium (water) having a water temperature of 37 ° C. was flown at a flow rate of 15 l / min in the housing 10, and hemoglobin was 12 g / dl in the capillary 13. Flow rate of bovine blood at 20 ° C: 4 l
Table 1 shows the results of evaluating the flow rate of air bubbles in the processing liquid discharge port 22 and the state of the residual liquid in the processing liquid discharge port 22 after the processing is completed.

[0043]

[Table 1] Bubble escape flow rate (l / min) Remaining liquid state Example 1 5.0 None Example 2 3.5 None Example 3 3.5 Yes Example 4 2.5 None Comparative example 1 5.0 Yes Comparative Example 2 Inability to remove air bubbles None.

As is apparent from the above results, according to the medical liquid processing apparatus of the present invention, it is clear that the efficiency of discharging the residual liquid and / or the processing liquid is improved.

[0045]

As described above, the medical liquid treatment apparatus of the present invention does not generate residual liquid or bubbles and has excellent discharge efficiency of the treatment liquid. It can be preferably applied to medical uses such as for connection with a device.

[Brief description of the drawings]

FIG. 1 is a longitudinal sectional view showing a first embodiment of a medical liquid treatment apparatus according to the present invention.

FIG. 2 is a longitudinal sectional view showing a second embodiment in the same manner.

FIG. 3 is a longitudinal sectional view showing a third embodiment in the same manner.

FIG. 4 is a schematic explanatory view showing an example of a conventional medical liquid treatment apparatus.

FIG. 5 is a schematic explanatory view showing another example of the conventional medical liquid treatment apparatus.

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 10 Housing 11 Inlet 12 Outlet 13 Thin tube 14 Processing liquid introduction chamber 15 Introduction port 16 Seal part 17 Seal part 18 Partition wall 19 O-ring 20 Processing liquid discharge chamber 21 Main opening 22 Processing liquid discharge port 23 Sub opening 24 Sub opening Department

Claims (5)

(57) [Claims] A housing provided with a liquid processing mechanism therein; a processing liquid discharge chamber disposed on a side of the housing; a main opening formed in an upper portion of the processing liquid discharge chamber; In the medical liquid treatment apparatus having a treatment liquid discharge port disposed vertically downward of the housing in communication with the processing liquid discharge port, at a position near the bottom of the treatment liquid discharge chamber, with a smaller diameter than the main opening, And a sub-opening communicating with the processing liquid discharge port is provided. 2. The processing liquid discharge port has an inner wall formed with the main opening and the sub opening, and a wall from the main opening to the sub opening having a reduced diameter. 2. The medical liquid treatment apparatus according to 1. 3. The medical liquid processing apparatus according to claim 1, wherein the inner wall of the processing liquid discharge port is tapered so that the diameter of the hole from the main opening to the tip of the processing liquid discharge port increases. . 4. A housing having a liquid processing mechanism therein, a processing liquid discharge chamber disposed on a side of the housing, a main opening formed in an upper portion of the processing liquid discharge chamber, and a main opening formed in the processing liquid discharge chamber. And a processing liquid discharge port disposed vertically downward of the housing in communication with the processing liquid discharge device, in the processing liquid discharge chamber, the diameter of the main opening from the lower end of the main opening. A medical liquid treatment apparatus, wherein a sub-opening having a smaller diameter than the main opening and communicating with the processing liquid discharge port is provided at a lower position within a range not exceeding. 5. The medical liquid treatment apparatus according to claim 1, which is connected to an artificial lung.