JP3113844B2 - Cosmetics - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

[0001] The present invention relates to a cosmetic having improved transdermal absorption of a substance having a whitening effect.

[0002]

2. Description of the Related Art Conventionally, in cosmetics and the like, various substances have been used as components that exhibit a whitening effect by transdermal absorption. However, the stratum corneum, the outermost layer of the skin,
Because it has a physiological function as a barrier to prevent invasion of foreign substances from outside the body, simply adding such a substance to an external preparation does not provide sufficient transdermal absorbability, and the inherent function of the component Cannot be shown. In addition, many substances that exhibit an excellent whitening effect by being absorbed into the skin cannot exhibit their original effect because of their low transdermal absorption ability in the stratum corneum.

[0003] Therefore, in recent years, transdermal absorption enhancers such as dimethylsulfoxide, dimethylformamide, dimethylacetamide, and methyldecylsulfoxide have been used for the purpose of improving the transdermal absorbability of various substances. But,
These percutaneous absorption enhancers do not provide a satisfactory percutaneous absorption promotion effect, and may cause erythema on the skin due to strong skin irritation. Was not enough.

[0004]

SUMMARY OF THE INVENTION Accordingly, an object of the present invention is to provide a cosmetic composition having low skin irritation and improved transdermal absorption of a substance having a whitening effect.

[0005]

Means for Solving the Problems In view of such circumstances, the present inventors have conducted intensive studies. As a result, if a substance having a specific whitening effect and an oil agent having a specific solubility parameter are used in combination, skin irritation is low. It has been found that cosmetics exhibiting excellent whitening effect can be obtained because the percutaneous absorption of a substance having a good feeling in use and having a whitening effect is improved.

That is, the present invention relates to (A) a spiroether compound represented by the general formula (1)

[0007]

Embedded image

[Wherein the wavy line indicates that the bonding state may be either Z or E] and (B) an oil agent having a solubility parameter δ in the range of 15.7 <δ ≦ 21.0. It is intended to provide a cosmetic characterized by containing one or more kinds.

[0009]

BEST MODE FOR CARRYING OUT THE INVENTION In the present specification, a solubility parameter refers to a measure of compatibility between substances, and is obtained by calculating Hansen's three-dimensional solubility parameter using the following equation (i). . In the formula, each term on the right side is a calculation formula (ii) based on the molar attractive constant of Van Krevelen.
To (iv).

## EQU1 ## δ = (δd ² + δp ² + δh ² ) ^1/2 (i)

Δ: solubility parameter δd: term due to London's dispersive force (van der Waals force) (dispersion term) δp: term due to molecular polarity (polar term) δh: term due to hydrogen bond (hydrogen bond term)

Δd = ｄF _di / ΣV _i (ii) δp = (ΣF _pi ² ) ^1/2 / ΣV _i (iii) δh = (ΣF _hi / ＝ V _i ) ^1/2 (iv)

F _di , F _pi , F _hi ; molar attraction constant V _i ; molar volume

It should be noted that δd, δp, δh can be calculated from the above equations (ii) to (iv) based on the molar attraction constants (F _di , F _pi , F _hi ) of the atomic groups as described above. in the present specification, with respect to the molar attraction constants, using the Van Krevelen Rayori determined value, molar volume (V _i) was used the volume value of a defined group of atoms by Fedor.

The component (A) spiroether compound represented by the general formula (1) used in the present invention is, for example, a chamomile of Matricaria spp.
84-388, 1992), Chrysanthemum genus Chrysanthemum (Agric. Biol. Chem. 48, 1367-
1369, 1984), which are reported to be obtained from several Asteraceae plants such as genus Tanacetam, Artemisia, and Leucansemum. Components obtained by solvent extraction, steam distillation, etc., are subjected to conventional chromatography. And subjecting it to isolation. This spiroether compound suppresses melanin production in melanocytes, reduces or eliminates pigmentation based on external stimuli such as ultraviolet rays, has an excellent effect of preventing and improving pigmentation, and has a skin whitening effect ( JP-A-7-20
No. 6657).

In the present invention, the spiroether compound is preferably incorporated in the total composition in an amount of 0.0001 to 15% by weight, more preferably 0.0001 to 10% by weight, and more preferably 0.001 to 10% by weight.
It is preferable to add 001 to 5% by weight because the feeling of use and stability are more excellent.

Examples of the oil agent having a solubility parameter δ of the component (B) used in the present invention in the range of 15.7 <δ ≦ 21.0 include, for example, ethyl arachidonic acid, ethyl linolenate, isononyl isononanoate, and isopalmitic acid. Octyl, isopropyl linoleate, octyl isoperargonate, oleyl linoleate, isotridecyl isononanoate, ethyl linoleate, isopropyl isostearate, isocetyl octanoate, oleyl eicosanoate, isostearyl octanoate, isodecyl pivalate, isodecyl isononanoate, eicosanoic acid Elsil, octyldodecyl oleate, isostearyl pivalate, isostearyl isostearate, isosetyl isostearate, isostearyl eicosanoate, octyldodecyl eicosanoate, oley Isopropyl acetate, octyldodecyl dimethyloctanoate, hexyldecyl dimethyloctanoate, oleyl myristate, stearyl eicosanoate, ethyl oleate, decyl oleate, isocetyl stearate, octyl stearate, octyl dodecyl stearate, isostearyl palmitate, Isocetyl palmitate, octyl palmitate, isostearyl myristate, isocetyl myristate, isotridecyl myristate, octyl dodecyl myristate,
Isostearyl laurate, hexyl isostearate, myristyl isostearate, lauryl isostearate, stearyl oleate, cetyl oleate, isobutyl stearate, isobutyl palmitate, isopropyl palmitate, octyl myristate, isodecyl laurate, butyl isostearate, pelargone Octyl acid, isopropyl myristate, isoamyl laurate, isohexyl laurate, myristyl neopentanoate, isobutyl pelargonate, lauryl palmitate, decyl myristate, ethyl stearate, ethyl palmitate, butyl myristate, ethyl laurate, methyl myristate , Methyl laurate, propylene glycol dinonanoate, diisopropyl sebacate,
Glyceryl trioctanoate, glyceryl tricaprate, diisobutyl adipate, neopentyl glycol dicaprate, propylene glycol dicaprate, dihexyl adipate, glyceryl triacetyl ricinoleate, diisopropyl adipate, glyceryl tricaprate, diglyceryl triisostearate, diethyl sebacate , Diglyceryl monoisostearate monomyristate, butyl adipate, dibutyl adipate,
Diisostearyl malate, octyl oxystearate, octyl methoxycinnamate, octyl dodecyl lactate, isostearyl lactate, oleyl lactate, methyl ricinoleate, octyl paradimethylaminobenzoate, myristyl lactate, dl-α-tocopherol, nicotinic acid dl−
Examples thereof include α-tocopherol, lauryl lactate, and diglyceryl monomyristate monoisostearate. Of these, those having a total carbon number of 10 to 90 are preferable, and those having a total carbon number of 20 to 80 are particularly preferable.

The oil component (B) can be used alone or in combination of two or more, but it is preferable to use two or more in combination, and (B-1) the solubility parameter δ is 15.7. One or more selected from oil agents in the range of <δ ≦ 17.2, and (B-2) selected from oil agents in which the solubility parameter δ is in the range of 17.5 ≦ δ ≦ 21.0. It is preferable to use one kind or a combination of two or more kinds.

Here, examples of the oil agent having a solubility parameter δ in the range of 15.7 <δ ≦ 17.2 used as the component (B-1) include, for example, ethyl arachidonic acid, ethyl linolenate, isononyl isononanoate, Octyl palmitate, isopropyl linoleate, octyl isoperargonate, oleyl linoleate, isotridecyl isononanoate, ethyl linoleate, isopropyl isostearate, isocetyl octanoate, oleyl eicosanoate, isostearyl octanoate, isodecyl pivalate, isodecyl isononanoate, Elsil eicosanoate,
Octyldodecyl oleate, isostearyl pivalate, isostearyl isostearate, isocetyl isostearate, isostearyl eicosanoate, octyldodecyl eicosanate, isopropyl oleate, octyldodecyl dimethyloctanoate, hexyldecyl dimethyloctanoate, oleyl myristate, eicosan Stearyl acid, Ethyl oleate, Decyl oleate, Isocetyl stearate, Octyl stearate, Octyl dodecyl stearate, Isostearyl palmitate, Isocetyl palmitate, Octyl palmitate,
Isostearyl myristate, isocetyl myristate, isotridecyl myristate, octyl dodecyl myristate, isostearyl laurate, hexyl isostearate, myristyl isostearate, lauryl isostearate, stearyl oleate, cetyl oleate, isobutyl stearate, isobutyl palmitate , Isopropyl palmitate, octyl myristate, isodecyl laurate, butyl isostearate,
Octyl pelargonate, isopropyl myristate, isoamyl laurate, isohexyl laurate, myristyl neopentanoate, isobutyl pelargonate, lauryl palmitate, decyl myristate, ethyl stearate, ethyl palmitate, butyl myristate, ethyl laurate, myristate Methyl, methyl laurate and the like are mentioned, and among these, isotridecyl isononanoate is particularly preferred.

Oils having a solubility parameter δ in the range of 17.5 ≦ δ ≦ 21.0 used as the component (B-2) include, for example, propylene glycol dinonanoate, diisopropyl sebacate, glyceryl trioctanoate, and tricaprin. Glyceryl acid, diisobutyl adipate, neopentyl glycol dicaprate, propylene glycol dicaprate, dihexyl adipate,
Glyceryl triacetyl ricinoleate, diisopropyl adipate, glyceryl tricaprate, diglyceryl triisostearate, diethyl sebacate, diglyceryl monoisostearate diglyceryl, dibutyl adipate, and the like. Of these, monomyristine monoisostearate Diglyceryl acid is particularly preferred.

When component (B-1) and component (B-2) are used in combination as component (B), isotridecyl isononanoate is used as component (B-1) and component (B-2)
It is particularly preferred to use diglyceryl monomyristate monoisostearate. In this case, another oil agent used as the component (B) may be used in combination.

The amount of component (B) is not particularly limited, but from the viewpoint of the percutaneous absorption promoting effect and the feeling of use of component (A), 0.001 to 40% by weight, preferably 0.1 to 40% by weight, based on the total composition. It is preferable that the content is 0.01 to 30% by weight, more preferably 0.01 to 10% by weight. In addition, as the component (B), the component (B
When using a mixture of component (B-1) and component (B-2), the weight ratio (B-1) / (B-2) of component (B-1) to component (B-2) in component (B) is 10%. / 1-2, especially 1
It is particularly preferred that it be in the range of 0/1 to 2/1.

The cosmetic of the present invention may further comprise a humectant as the component (C). The humectant is not particularly limited as long as it is used for ordinary cosmetics. For example, ethanol, glycerin, 1,3-butylene glycol, propylene glycol, dipropylene glycol, ethylene glycol, 1,4-butylene glycol , Diglycerin, polyglycerin such as triglycerin, glucose, maltose, maltitol, sucrose, fructose, threitol, erythritol, starch-degrading sugar and the like. Among these, ethanol,
1,3-butylene glycol and glycerin are particularly preferred from the viewpoint of feeling of use.

The amount of component (C) is not particularly limited, but is preferably 0.001 to 40% by weight, more preferably 0.01 to 30% by weight, and even more preferably 0.01 to 1% by weight, based on the total composition.
It is preferable to add 0% by weight, because it is more excellent in use feeling.

In the cosmetic of the present invention, in addition to the above-mentioned components, oils, organic acids, alkalis, surfactants, ultraviolet absorbers, powders, pigments other than those described above, as long as the effects of the present invention are not impaired. Dyes, preservatives / fungicides, antioxidants, chelating agents,
Components commonly used in pharmaceuticals such as thickeners, fragrances and water, quasi-drugs, cosmetics and the like can be appropriately compounded.

Specific examples of the oil component include liquid paraffin, squalane, higher fatty acids and higher alcohols; examples of the organic acids include citric acid and lactic acid; and examples of the alkalis include caustic soda and triethanol. Amines and the like.

Among the surfactants, hydrophilic surfactants include nonionic surfactants such as polyoxyethylene castor oil, polyoxyethylene hydrogenated castor oil,
Polyoxyethylene castor oil or hydrogenated castor oil derivatives such as polyoxyethylene hydrogenated castor oil laurate, polyoxyethylene hydrogenated castor oil isostearate, polyoxyethylene hydrogenated castor oil pyroglutamic acid isostearic acid diester; polyoxyethylene sorbitan monolaurate; Polyoxyethylene sorbitan fatty acid esters such as polyoxyethylene sorbitan monopalmitate, polyoxyethylene sorbitan monostearate, polyoxyethylene sorbitan monoisostearate, polyoxyethylene sorbitan tetraoleate; polyoxyethylene glyceryl monostearate, poly Polyoxyethylene glycos such as oxyethylene glyceryl monoisostearate and polyoxyethylene glyceryl triisostearate Fatty acid esters of polyoxyethylene lauryl ether, polyoxyethylene hexyl decyl ether, polyoxyethylene cetyl ether, polyoxyethylene stearyl ether, polyoxyethylene octyl dodecyl ether, polyoxyethylene behenyl ether, polyoxyethylene nonyl phenyl ether, Polyoxyethylene alkyl ethers such as polyoxyethylene polyoxypropylene decyl tetradecyl ether; polyoxyethylene addition surfactants such as polyoxyethylene fatty acid esters such as polyoxyethylene monooleate; polyglycerin alkyl ether; Glycerin fatty acid esters, sucrose fatty acid esters and the like can be mentioned.

As anionic surfactants, polyoxyethylene alkyl sulfate surfactants such as polyoxyethylene lauryl ether triethanolamine sulfate; N-acyl amino acid salts such as sodium lauroyl sarcosine and sodium lauroyl methylalanine; Surfactants: sodium polyoxyethylene lauryl ether phosphate, sodium polyoxyethylene cetyl ether phosphate, dipolyoxyethylene alkyl ether phosphoric acid, tripolyoxyethylene alkyl ether phosphoric acid,
Dipolyoxyethylene nonyl phenyl ether phosphoric acid,
And polyoxyethylene alkyl ether phosphate surfactants such as sodium polyoxyethylene lauryl ether phosphate and sodium dipolyoxyethylene lauryl ether phosphate. Examples of amphoteric surfactants include alkyl betaines, alkyl amido betaines, and alkyl amido betaines, and cationic surfactants include di-long chain alkyl quaternary ammonium salts, mono-long chain alkyl quaternary ammonium salts, and di long chain alkyls. Examples include polyoxyethylene quaternary ammonium salts, bis (hydroxyalkyl) quaternary ammonium salts, and quaternary ammonium salts having an amide / ester bond.

Of these, polyoxyethylene-added nonionic surfactants are preferred, and those having an ethylene oxide addition mole number of 20 to 60 are particularly preferred.

Examples of the ultraviolet absorber include benzophenone, 4-tert-butyl-4'-methoxy-dibenzoylmethane, glyceryl ethylhexanoate dimethoxycinnamate, 2-ethylhexyl-4-methoxycinnamic acid, p-
Examples include aminobenzoic acid esters and phenyl salicylate.

The cosmetic of the present invention can be produced according to a usual method, and may be in any form such as liquid, water-in-oil or oil-in-water emulsion, gel, paste, and solid. be able to. In particular, it is suitable as a skin cosmetic such as a lotion, a milky lotion, a cream, and a serum.

[0032]

EFFECT OF THE INVENTION The cosmetic of the present invention has a low irritating property to the skin, a good feeling upon use, an improved percutaneous absorption of a substance having a whitening effect, which is an active ingredient thereof, and a low dose. Excellent whitening effect can be obtained.

[0033]

EXAMPLES The present invention will be described below in detail with reference to examples, but the present invention is not limited to these examples. The spiroether compounds used in the following examples are represented by the spiroether compound Z in the case where the bond state of the wavy line in the general formula (1) is Z, and the spiroether compound E in the case where the bond state is E.

Examples 1 to 10 and Comparative Examples 1 and 2 Cosmetics having the compositions shown in Tables 1 and 2 were produced by a conventional method.
The skin penetration of a spiro ether compound, a substance having a whitening effect, was tested by the following method. The results are shown in Tables 1 and 2.

(Test Method) A fixed amount of cosmetic was applied to the skin surface of the washed Yucatan micropig, and the room was kept in a constant temperature room (temperature: 37 ° C., humidity: saturated).
To leave. After a certain period of time, the unpermeated components remaining on the skin surface are removed, and the permeated components are extracted and collected.
The percutaneous absorption of the spiroether compound was measured by using the above method. The percutaneous absorption was shown as a value per unit area (μg / cm ² ).

[0036]

[Table 1]

[0037]

[Table 2]

As is clear from Tables 1 and 2, the cosmetic of the present invention is superior in skin permeability to the cosmetic of Comparative Example.
It was excellent in whitening effect. In addition, high security,
The feeling of use was also good.

Examples 11 to 12 and Comparative Example 3 Whitening cosmetics having the compositions shown in Table 4 were produced by a conventional method. For these whitening cosmetics, the skin penetration of the spiroether compound was tested in the same manner as in Examples 1 to 10, and the whitening effect was tested by the following method. Table 4 shows the results.

(Whitening Effect Test on UV-B-Induced Pigment Spot) The inner arm of 20 healthy male subjects was irradiated with ultraviolet rays in the UV-B region twice the minimum erythema amount once a day for 2 days. The whitening effect by continuously applying the sample to the test site twice a day on the induced pigment spots for one month was examined. The evaluation was performed using a color difference meter (manufactured by Minolta, CR-300), and the L ^* value was calculated from the obtained Munsell value.
The ΔΔL ^* value representing its recovery was used. The ΔΔL ^* value was defined as follows. The L ^* values of the sample application test site immediately before the start of sample application and the sample unapplied test site are L ₀ and L, respectively.
₀ represents _', the L ^* value of sites each after continuous coating 1 month L _1, L _1', respectively, the DerutaderutaL ^* by the following equation as.

(Equation 3) ΔΔL ^* = (L ₁ −L ₀ ) − (L _{1 ′} −L _{0 ′} )

The evaluation was shown by the average value of the evaluation points of 20 subjects. Table 3 shows the relationship between the evaluation points and the criteria.

[0043]

[Table 3]

[0044]

[Table 4]

Example 13 and Comparative Example 4 Cosmetics having the composition shown in Table 5 were produced by a conventional method, and their anti-inflammatory effects were evaluated. Table 5 shows the results.

(Evaluation method) Toshiba FS-20 was placed on the inner part of the upper arm of 20 healthy male subjects.
Using an SE lamp, ultraviolet rays in the UV-B region were irradiated once with twice the minimum erythema amount (2 MED). Immediately after that, 15 μl of each cosmetic was applied, and after 24 hours, redness (a ^* value) and skin temperature were measured. Redness is color difference meter (Minolta, CR
-300) and a ^* value was calculated from the obtained Munsell value. A ^* 24 hours after UV-B irradiation,
Δ shows how much it increased compared to the a ^* value before UV-B irradiation.
a ^* value. The skin temperature was measured using a radiation thermometer (THI-500, manufactured by Tasco Japan).
The results were shown as average values.

[0047]

[Table 5]

Examples 14 to 18 Whitening cosmetics having the following compositions were produced by a conventional method.

Example 14 (Emulsion) (Table 6) (Components) (% by weight) (1) Palmitic acid 1.0 (2) Stearic acid 1.0 (3) Cetanol 1.0 (4) Monohexadecyl phosphorus Acid sodium salt 2.0 (5) sorbitan monostearate 0.5 (6) glycerin 10.0 (7) ethanol 5.0 (8) spiroether compound Z 0.5 (9) isotridecyl isononanoate (δ = 16.56 3.0) (10) diglyceryl monoisostearate monomyristate (δ = 18.43) 1.0 (11) lactic acid 2.0 (12) arbutin 3.0 (13) purified water balance

Example 15 (Emulsion) (Table 7) (Components) (% by weight) (1) 1,3-butylene glycol 3.0 (2) Glycerin 5.0 (3) Sodium hyaluronate 0.2 (4) ) Polyacrylic acid (Carbopol; manufactured by Goodrich Co.) 0.2 (5) Potassium hydroxide 0.06 (6) Polyoxyethylene hydrogenated castor oil (40E.O. ^{* 1} ) 1.0 (7) α- Monoisostearyl glyceryl ether 0.2 (8) Sorbitan monostearate 0.2 (9) Spiroether compound Z 0.01 (10) Isotridecyl isononanoate (δ = 16.56) 5.0 (11) Monomyristine monoisostearate Diglyceryl acid (δ = 18.43) 1.0 (12) succinic acid 1.5 (13) urea 2.0 (14) ε-aminocaproic acid 1.0 (15) chamomile (chamomile liquid; Ichimaru Falco) Company Ltd.) 5.0 (16) bovine placental extract (Biofaruko CP-20; manufactured by Ichimaru Pharcos Co., Ltd.) 1.0 (17) Purified water Balance * 1: ethylene oxide addition molar number

Example 16 (Cream) (Table 8) (Components) (% by weight) (1) Stearic acid 2.0 (2) Isotridecyl isononanoate (δ = 16.56) 7.0 (3) Monomyristine monoisostearate Acid diglyceryl (δ = 18.43) 4.0 (4) cholesterol 3.0 (5) cetanol 2.0 (6) 2-arginine hexahexyl phosphate 2.0 (7) polyoxyethylene hydrogenated castor oil (40E .O. ^{* 1} ) 0.5 (8) α-monoisostearyl glyceryl ether 0.2 (9) Spiroether compound Z 0.01 (10) Spiroether compound E 0.01 (11) Succinic acid 1.0 (12) Kojic acid 1.0 (13) Glycerin 5.0 (14) Sodium hyaluronate 0.05 (15) Polyacrylic acid (Carbopol; Goodrich Co.) 0.5 (16) NaOH Um 0.15 (17) Purified water Balance * 1: ethylene oxide addition molar number

Example 17 (creamy foundation) (Table 9) (Components) (% by weight) (1) Titanium oxide 6.0 (2) Sericite 8.0 (3) Iron oxide (red, yellow, black) 1.2 (4) Sorbitan fatty acid ester (Reodol MO-6; manufactured by Kao Corporation) 5.0 (5) Isotridecyl isononanoate (δ = 16.56) 12.0 (6) Monoglycristyl monoisostearate (δ = 18.43) 3.0 (7) Dimethylpolysiloxane (KF96A 6cs; manufactured by Shin-Etsu Chemical Co., Ltd.) 30.0 (8) Spiroether compound Z 0.01 (9) Glycerin 2.0 (10) Purified water balance

Example 18 (Powder Foundation) (Table 10) (Components) (% by weight) (1) Titanium oxide 10.0 (2) Sericite 30.0 (3) Talc balance (4) Kaolin 5.0 ( 5) Bengala 2.0 (6) Yellow iron oxide 2.5 (7) Black iron oxide 0.1 (8) Polyethylene powder 4.0 (9) Isotridecyl isononanoate (δ = 16.56) 1.5 (10) Mono Diglyceryl monomyristate isostearate (δ = 18.43) 0.6 (11) Dimethyl polysiloxane (KF96A 6cs; manufactured by Shin-Etsu Chemical Co., Ltd.) 12.0 (12) Spiroether compound Z 0.01

Each of the whitening cosmetics obtained in Examples 14 to 18 had good transdermal absorbability of the active ingredient, excellent whitening effect, high safety, and good feeling in use. .

────────────────────────────────────────────────── ─── Continuation of front page (72) Inventor Yumiko Sato 2-1-3 Bunka, Sumida-ku, Tokyo Inside Kao Research Institute (56) References JP-A-59-73508 (JP, A) JP-A-59 JP-A-104308 (JP, A) JP-A-61-227514 (JP, A) JP-A-61-207307 (JP, A) JP-A-8-217625 (JP, A) JP-A-5-192560 (JP, A) JP-A-5-124950 (JP, A) JP-A-1-186811 (JP, A) JP-A-61-210010 (JP, A) JP-A-6-157240 (JP, A) 20227 (JP, A) JP-A-63-280006 (JP, A) JP-A-6-32728 (JP, A) (58) Fields investigated (Int. Cl. ⁷ , DB name) A61K 7/00 A61K 9 / 00

Claims (5)

(57) [Claims] (A) A spiro ether compound represented by the general formula (1): [Wherein the wavy line indicates that the bonding state may be either Z or E] and (B) the solubility parameter δ is 1
5.7 <δ ≦ 21.0 Cosmetics characterized by containing one or more selected from oils in the range of 21.0. 2. The cosmetic according to claim 1, wherein the component (B) is a combination of two or more oil agents having a solubility parameter δ in the range of 15.7 <δ ≦ 21.0. . 3. Component (B) comprises (B-1) one or more oil agents selected from oil agents having a solubility parameter δ in the range of 15.7 <δ ≦ 17.2, and (B-2) The cosmetic according to claim 1 or 2, wherein the cosmetic parameter is one or a combination of two or more selected from oil agents having a solubility parameter δ in the range of 17.5 ≦ δ ≦ 21.0. 4. Component (B) comprises (B-1) and (B-
2) by weight ratio (B-1) / (B-2) = 10/1 to 1
The cosmetic according to claim 3, wherein the cosmetic is combined at a ratio of / 2. 5. The method according to claim 1, further comprising (C) a humectant.
The cosmetic according to any one of claims 4 to 4.