JP2971446B2 - Nori treatment agent and treatment method - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a treating agent and a treating method for a glue, especially a cultured glue, and more specifically, an agent for controlling or preventing a disease occurring on a glue or a glue activating agent and a disease occurring on a glue. And a method for controlling or preventing Nori.

[0002]

2. Description of the Related Art Cultured glue includes Olpidiopsi.
s ) Pythiu fungus, Pythiu
m ) There are many diseases such as red rot disease caused by a genus bacterium, green spot disease caused by bacteria as a pathogenic bacterium, pseudo-spotted wilt disease, or bruise disease. As a method for controlling these diseases,
A method for long-term drying using the difference in resistance between the pathogen and Nori for drying, a method for freezing using the difference in freezing resistance between the pathogen and Nori, and a method for the acid or alkali of the pathogen and Nori A method of performing an acid or alkali treatment using a difference in resistance is known.

[0003] The causal fungus of Nori vase is Chytosis (Chyt
ridiomycetes) and has properties similar to glue as properties. For this reason, the pathogenic bacteria have a drying resistance, a freezing resistance, and an acid / alkali resistance that are equal to or higher than those of glue, and it is difficult to control the pathogenic bacteria using the above-mentioned technology. A method using chitosan (Japanese Unexamined Patent Publication No. 4-40838 and Japanese Patent Publication No.
No. 8762) and a method using a water-soluble inorganic compound exhibiting alkalinity (Japanese Patent Application Laid-Open No. 58-10509).

[0004] Further, as for the rash, the use of various acids for the control thereof (JP-B-56-12601, JP-A-1-279805, JP-A-7-308)
No. 136) is known. These control methods do not provide sufficient control effects, require long treatment times, require excessive labor, and involve the dangers of processing chemicals. There is a strong need for the development of excellent control agents and control methods.

[0005] Further, there is also a demand for improving the quality of the paste such as paste color and luster. As a quality improvement method, a method using a seaweed culture fertilizer containing phytic acid as an active ingredient (Japanese Patent Application Laid-Open
56-155085 JP), etc. Akira, a method for activating the seaweed is known by improving the growth using various fertilizers.

[0006]

SUMMARY OF THE INVENTION It is an object of the present invention to provide a method for effectively and efficiently controlling or preventing various diseases such as vase-fungus disease and madder disease which occur on glue and a controlling agent or a prophylactic agent. Is to do. Another object of the present invention is to provide a glue activating method and an activator that improve the quality of glue such as glue color and luster.

[0007]

The present invention provides a compound represented by the general formula (I):

[0008]

Embedded image

(Wherein, R ¹ , R ² and R ³ are the same or different and each represent hydrogen or straight-chain or branched alkyl having 1 to 30 carbon atoms, and X ⁻ represents an anion. ), Or a hydrate thereof (hereinafter collectively referred to as pyridinium salts) as an active ingredient. The present invention also relates to a glue treatment method, comprising immersing glue in an aqueous solution containing the pyridinium salt or spraying the aqueous solution on the glue.

[0010]

BEST MODE FOR CARRYING OUT THE INVENTION In the above definitions of each group, R ¹ ,
The alkyl of R ² and R ³ is a linear or branched alkyl group having 1 carbon atom.
-30, for example, methyl, ethyl, propyl, isopropyl, butyl, sec-butyl, tert-butyl, pentyl, 2-pentyl, 3-pentyl, isoamyl, hexyl, heptyl, octyl, nonyl, decyl, undecyl, dodecyl, tridecyl , Tetradecyl, pentadecyl, hexadecyl (cetyl), heptadecyl, octadecyl, nonadecyl, eicosyl, heneicosyl, docosyl, tricosyl, tetracosyl, pentacosyl, hexacosyl, heptacosyl, octacosyl, nonacosyl, triacontyl and the like.

The alkyls of R ² and R ³ are the same or different and are preferably the aforementioned alkyls having 1 to 6 carbon atoms. As the substituents of the substituted alkyl, the same or different
And 3, for example, halogen, hydroxy, alkyl-substituted or unsubstituted aryl, alkyl-substituted or unsubstituted amino, alkoxy, alkanoyl, aroyl, alkoxycarbonyl, aryloxycarbonyl.

The alkyl moiety of the alkoxy, alkanoyl, alkoxycarbonyl, alkyl-substituted amino and alkyl-substituted aryl is a straight-chain or branched C1-C6 alkyl moiety.
For example, the alkyl exemplified above can be mentioned. Examples of the aryl moiety of aryl and aroyl, aryloxycarbonyl and alkyl-substituted aryl include phenyl, naphthyl and the like.

Halogen represents each atom of fluorine, chlorine, bromine or iodine. Examples of the anion include a hydroxyl ion, a halogen ion, an anion derived from an inorganic acid, an anion derived from an organic acid, and the like. Examples of the halogen ion include a fluorine ion, a chlorine ion, a bromine ion, and an iodine ion. As anions derived from inorganic acids,
For example, nitrate ion, sulfate ion, phosphate ion, carbonate ion and the like can be mentioned. As anions derived from organic acids,
Examples include carboxylate ions such as formate ion, acetate ion, lactate ion, citrate ion, and glutamate ion.

Specific examples of the pyridinium salt represented by the general formula (I) include octylpyridinium chloride, octylpyridinium bromide, laurylpyridinium chloride, laurylpyridinium bromide, cetylpyridinium chloride (hexadecylpyridinium chloride), and cetylpyridinium bromide (hexyl). Decylpyridinium bromide), 4-methyl-octylpyridinium chloride, 4-methyl-octylpyridinium bromide, 4-methyl-octadecylpyridinium chloride, 4-methyl-octadecylpyridinium bromide and the like. These are known compounds and are available as commercial products.

The glue-treating agent of the present invention comprises a pyridinium salt as defined above, and may contain an acid, a chelating agent, a buffer, a nutrient, an organic nutrient, a pigment, and the like, if necessary. Examples of the acid include organic acids such as malic acid and citric acid, and inorganic acids such as phosphoric acid, hydrochloric acid, and sulfuric acid. Examples of the buffer include a phosphate buffer, a citrate buffer and the like. Examples of the chelating agent include ethylenediaminetetraacetic acid, hydroxyethylethylenediaminetriacetic acid, diethylenetriaminepentaacetic acid, and salts thereof. Examples of the salt include salts with sodium, potassium and the like. Examples of the nutrients include sodium nitrate, potassium nitrate, urea, ammonium sulfate, sodium phosphate, sodium hydrogen phosphate, potassium phosphate and the like. Organic nutrients include amino acids, sugars and the like. Examples of the pigment include a caramel pigment.

The glue treating agent of the present invention preferably contains the above-mentioned chelating agent in the pyridinium salts defined above. The chelating agent is added to 1 part by weight of the pyridinium salt.
0.001 to 5000 parts by weight, preferably 0.01 to
It is adjusted to be 500 parts by weight, more preferably 0.1 to 50 parts by weight. Further, the paste processing agent of the present invention preferably contains the pyridinium salts defined above and the above-mentioned acid. The acid is used in an amount of 0.001 to 1000 parts by weight, preferably 0.01 to 1000 parts by weight, based on 1 part by weight of the pyridinium salt.
It is adjusted to be 100 parts by weight, more preferably 0.1 to 10 parts by weight. Further, the paste treatment agent of the present invention preferably contains the pyridinium salts defined above, the acid described above, and the chelating agent described above. The addition ratio of the chelating agent and the acid is the same as described above.

The dosage form of the treating agent of the present invention may be any of liquid, powder, fine granules, granules, tablets, capsules and the like. This is these dosage forms can be prepared in a conventional manner. Examples of the liquid solution include distilled water and artificial seawater. As the glue to which the present invention is applied, bovine henori (Protoflori)
Any algae may be used as long as they belong to the red algae belonging to Deophyceae). Nori used in aquaculture, such as Porphyra
Nori belonging to the genus are preferred, and Asasanori, Susabinori or a Nori cultivar for cultivation selected and bred therefrom are particularly preferred. In the present invention, the target is seaweed that is being cultured.

The glue diseases to which the present invention is applied include chytrids (Chloromycetes, rust molds, chytrids, etc.)
ytridiomycetes), diseases such as scabs and the like caused by oomycetes (Oomycetes), and diseases such as green spots and filamentous bacteriosis caused by bacteria. .
Particularly preferably used diseases include pot-like fungus disease and scab disease.

The method for controlling or preventing Nori disease in the present invention means a method for treating Nori disease or a method for preventing Nori disease from being affected by the disease. Therefore, the method of the present invention can be used for the prevention of disease on disease-free Nori, the treatment of disease against diseased Nori, and the prevention of recurrence, but is more preferably used for the treatment of disease.

The method for activating glue according to the present invention comprises:
It means a method to improve the quality such as gloss. When using the paste processing agent of the present invention, the type and growth status of the paste,
Although it varies depending on the treatment method of the treatment agent and the like, the concentration of the treatment agent containing the pyridinium salt is 1 to 1000 ppm, preferably 2.5 to 500 pp as the pyridinium salt concentration.
m, more preferably 10 to 250 ppm after dissolving in a solution, glue in the solution for 1 second to 60 minutes,
The immersion can be carried out preferably by immersion for 15 seconds to 15 minutes, more preferably for 30 seconds to 5 minutes, or by spraying the solution on paste.

The solution used in carrying out the present invention includes:
Although water, salt water, seawater, a buffer solution, and the like can be used, seawater is preferably used. Examples of the buffer include a citrate buffer, a phosphate buffer and the like. The treating agent solution containing the pyridinium salts of the present invention includes chelating agents such as malic acid, citric acid, phosphoric acid, hydrochloric acid, and sulfuric acid, ethylenediaminetetraacetic acid, hydroxyethylethylenediaminetriacetic acid, diethylenetriaminepentaacetic acid, and salts thereof. It is preferable to contain an agent, nutrients such as sodium nitrate, potassium nitrate, urea, ammonium sulfate, sodium phosphate and potassium phosphate, and organic nutrients such as amino acids and saccharides. By adding an acid, the action of controlling or preventing glutinous diseases of pyridinium salts is improved. By adding the chelating agent to the pyridinium salts, the action of the pyridinium salts can be effectively and stably obtained.

The concentration of the acid used is from 1 to 100,000 pp
m, preferably 100 to 10,000 ppm. The concentration of the chelating agent used is 1 to 10,000 ppm, preferably 10 to 5,000 ppm. Hereinafter, the present invention will be described specifically with reference to examples.

[0023]

【Example】

Example 1 Cetylpyridinium chloride monohydrate (manufactured by Wako Pure Chemical Industries, Ltd.) was used in an amount of 5 mg, 50 mg, 500 mg, and cation-H (octylpyridinium chloride 25%).
20mg, 200m
g and 2000 mg were dissolved in 1 liter of seawater, and 5 ppm, 50 ppm and 500 ppm of each pyridine compound were dissolved.
A test solution of ppm was prepared.

After adjusting the solution to 12 ° C. in a thermostat,
The leaves of Asakusanori, which had been infected with the pot-shaped fungus, and had a leaf length of about 3 cm (hereinafter simply referred to as "Nori leaves") were immersed in the respective solutions for 5 minutes to perform immersion treatment. After the immersion treatment, the glue leaves were thoroughly washed with clean seawater to remove the test solution, and each of the three test specimens was placed in a 10 cm-diameter glass dish filled with 30 ml of clean seawater for each test plot.
The culture was allowed to stand still in a 15 ° C. constant temperature culture tank for 7 days under the condition of time illumination.

After completion of the culture, the Nori leaf body was observed under a microscope,
The survival and death of the pot-like fungi and the degree of damage to the laver leaves by the test solution were confirmed to determine the control effect. A section immersed in seawater instead of the test solution was provided as an untreated control section. The results are shown in Table 1.

[0027]

[Table 1]

A 5 ppm solution of cetylpyridinium chloride monohydrate was found to have an inhibitory effect on pot-like fungi,
m, 500 ppm solution showed a complete bactericidal effect.
However, in the solution of 50 ppm or more, damage to the laver leaves was observed. 5 pp for octylpyridinium chloride
m solution, an inhibitory effect on pot bacilli was observed.
A complete sterilization effect was observed with the 00 ppm solution. However, nodules were found in the Nori leaf body with the 500 ppm solution.

Example 2 Kationogen H (manufactured by Daiichi Kogyo Kagaku Co., Ltd.) and malic acid (manufactured by Wako Pure Chemical Industries, Ltd.) were diluted with seawater to give 3.13 to 100 ppm of octylpyridinium chloride and 0 to malic acid. Twenty-eight combinations of solutions shown in Table 2 consisting of 2.0% dilutions were prepared.

After adjusting each solution to a water temperature of 12 ° C. in a constant temperature bath, a glue leaf body having a leaf length of about 3 cm infected with a pot-shaped fungus was immersed in each test solution for 5 minutes. After the immersion treatment, the glue leaves were thoroughly washed with clean seawater to remove the test solution, and then, each of the three test specimens was placed in a 10 cm-diameter glass dish filled with 30 ml of clean seawater for each test plot.
The culture was allowed to stand for 7 days in a thermostat at 15 ° C. under 0-hour illumination. After completion of the culture, the Nori leaf was observed under a microscope, and the control effect was determined by confirming the survival and death of the pot-like fungus and the degree of damage to the Nori leaf by the test solution.

The results are shown in Table 2.

[0032]

[Table 2]

Octylpyridinium chloride 12.5
A complete sterilization effect of the fungi was observed with the test solution of not less than ppm, and even at 6.25 ppm, complete sterilization was not achieved. However, the growth of the fungi was suppressed and the expansion of the lesions was stopped. Was. However, in the section treated with the test solution of 100 ppm, dead cells were scattered in the nori leaf body, resulting in damage.

Example 3 A leafy leaf body of a leaf of about 7 cm which was artificially infected in an indoor culture flask and which was infected with the disease, the same as that shown in Example 2, was used.
The immersion treatment was performed with eight kinds of test solutions at a water temperature of 12 ° C. for 5 minutes. After the immersion treatment, the glue leaves were thoroughly washed with clean seawater to remove the test solution, and then housed individually for each test plot in a 10 cm diameter glass dish filled with 30 ml of clean seawater. The culture was allowed to stand still for 4 days in a 15 ° C. constant temperature culture tank under the conditions of time illumination. After completion of the cultivation, the Nori leaf was observed under a microscope, and the control effect was determined by confirming the survival and death of the fungus and the degree of damage of the Nori leaf by the test solution.

The results are shown in Table 3.

[0036]

[Table 3]

When octylpyridinium chloride alone was used, the concentration was 12.5 ppm or more, and when malic acid diluent was used alone, the concentration was reduced to 2.0%, and the disease control effect was recognized. On the other hand, when both agents were used in combination, a controlling effect was observed in a combination solution having a concentration of octylpyridinium chloride of at least 3.1 ppm and malic acid of at least 0.5%, and a synergistic effect of both agents was observed. In addition,
No change was observed in the injury intensity against glue even when both agents were used in combination.

Example 4 Cationogen H (manufactured by Daiichi Kogyo Co., Ltd.) 10 mg, 10 mg
0mg, 1000mg, 2000mg or 4000mg
And malic acid (10 g) dissolved in 1 liter of seawater, octylpyridinium chloride (2.5 ppm, 25 pp)
A mixed test solution containing m, 250 ppm, 500 ppm or 1000 ppm and a 1.0% solution of malic acid was prepared.

After the test solution was adjusted to a water temperature of 12 ° C. in a thermostat, an artificially infected leafy leaf of about 7 cm in leaf length, which was infected with the disease, was cultured in an indoor culture flask for 15 seconds, 30 seconds, and 60 seconds. The immersion treatment was performed for 5 minutes, 10 minutes, and 15 minutes, respectively. An immersion treatment was performed in seawater to which neither octylpyridinium chloride nor malic acid was added, and a control group without addition was used. After the immersion treatment, the glue leaves were thoroughly washed with clean seawater to remove the test solution, and then housed individually for each test plot in a glass dish of 10 cm in diameter filled with 30 ml of clean seawater. 15 ° C under the condition of time lighting
The culture was allowed to stand for 4 days in a constant temperature culture tank. After completion of the cultivation, the Nori leaf was observed under a microscope, and the control effect was determined by confirming the survival and death of the fungus and the degree of damage of the Nori leaf by the test solution.

The results are shown in Table 4.

[0041]

[Table 4]

When 1.0% of malic acid and octylpyridinium chloride are used in combination, 2.5 ppm of octylpyridinium chloride is subjected to a dipping treatment for 30 seconds or more to obtain 2
At 5 ppm or more, the immersion treatment for 15 seconds or more showed the effect of controlling scab and controlling disease. Octylpyridinium chloride at 250 ppm for 5 minutes or more
Damage was observed in the immersion treatment at 00 ppm for 30 seconds or more and at 1000 ppm for 15 seconds.

Example 5 Cetylpyridinium chloride and disodium ethylenediaminetetraacetate (manufactured by Dojindo Kagaku Kenkyusho) were diluted with seawater to give cetylpyridinium chloride of 1.25 to 10 p.
pm, disodium ethylenediaminetetraacetate 100-
Fifteen combinations of test solutions shown in Table 5 were prepared, consisting of 200 ppm dilutions.

After each solution was adjusted to a water temperature of 12 ° C. in a constant temperature bath, a glue leaf body having a leaf length of about 3 cm infected with a pot fungus was immersed in each test solution for 5 minutes. After glue Hatay after dipping treatment was removed thoroughly washed to test solution clean seawater, houses three each member in each test group in a glass petri dish having a diameter 10cm filled with clean seawater 30 ml, 1
The culture was allowed to stand still in a 15 ° C. constant temperature culture tank for 7 days under 0-hour lighting conditions. After completion of the culture, the Nori leaf was observed under a microscope, and the survival and death of the pot-like fungi and the degree of damage to the Nori leaf by the test solution were confirmed to determine the control effect. The results are shown in Table 5.

[0045]

[Table 5]

Compared to the use of cetylpyridinium chloride alone, disodium ethylenediaminetetraacetate 100 pp
m doubles the potato disease control effect to 200 pp.
m was increased by a factor of 4 when used in combination. In addition, the combined use of disodium ethylenediaminetetraacetate did not particularly increase the degree of damage to the Nori leaf.

Example 6 A test stock solution containing 9 g of cetylpyridinium chloride in a total volume of 1 liter was prepared. This undiluted test solution in seawater,
1/300, 1/600, 1/1200, 1/2400
The test solution was diluted by a factor of two to prepare four types of test solutions containing cetylpyridinium chloride at various concentrations and a control group containing no test stock solution.

After adjusting each test solution to a water temperature of 12 ° C. in a constant temperature bath , a 4 cm long glue net having glue leaves, which had become yellowish brown due to lack of nutrients, was grown on each test solution for 5 minutes. An immersion treatment was performed. After the immersion treatment, the glue net was sufficiently washed with clean seawater to remove the test solution, and then 67 ppm of sodium nitrate and 16 ppm of sodium hydrogen phosphate were used.
Each test group was housed in a 2 L glass beaker filled with seawater enriched with, and subjected to aeration and agitation culturing for 7 days in a 15 ° C constant temperature bath under the conditions of 5000 lux, 12 hours of illumination, and 12 hours of darkness. . After completion of the cultivation, the glue-leaved laver nets were spread in a white vat filled with seawater, and the color tone of the glue-leaves was compared by visual observation.

The results are shown in Table 6.

[0050]

[Table 6]

At the start of the test, the leaf color tone was light yellow-brown, but by culturing for 7 days in seawater reinforced with nitrogen and phosphorus, the color tone of the glue leaf increased in blackness and the color tone was improved. . The improvement effect is cetylpyridinium chloride7.
The treatment group with 5 ppm or more showed an enhancement effect as compared with the control group, and the treatment group with 30 ppm showed the highest effect.

Example 7 18 g of octylpyridinium chloride and 30 g of disodium ethylenediaminetetraacetate were dissolved in pure water to prepare a stock solution having a total volume of 1 liter. This test stock solution was treated with seawater in 1/300, 1/600, 1/1200,
After diluting by 1 / 2400-fold, four types of test solutions containing octylpyridinium chloride at various concentrations and a total of five types of control solutions containing no test stock solution were prepared.

[0053] Each test solution was adjusted to a water temperature 12 ° C. in a constant temperature bath for 5 minutes glue leaves body faded tan lack nutrient glue network length 4cm was epiphytic in each test solution An immersion treatment was performed. After the immersion treatment, the glue net was sufficiently washed with clean seawater to remove the test solution, and then 67 ppm of sodium nitrate and 16 ppm of sodium hydrogen phosphate were used.
Each test group was housed in a 2 L glass beaker filled with seawater enriched with, and subjected to aeration and agitation culturing for 7 days in a 15 ° C constant temperature bath under the conditions of 5000 lux, 12 hours of illumination, and 12 hours of darkness. . After completion of the cultivation, the glue-leaved laver nets were spread in a white vat filled with seawater, and the color tone of the glue-leaves was compared by visual observation.

Table 7 shows the results.

[0055]

[Table 7]

At the start of the test, the leaf color tone was light yellow-brown, but by culturing for 7 days in seawater reinforced with nitrogen and phosphorus, the color tone of the glue leaf increased in blackness and the color tone was improved. . The improvement effect was seen in the treatment group with octylpyridinium chloride concentration of 30 ppm or more as compared with the control group, and the highest effect was shown in the 60 ppm treatment group.

Example 8 A test solution was prepared by dissolving cetylpyridinium bromide monohydrate (manufactured by Wako Pure Chemical Industries, Ltd.) in seawater to the concentration shown in Table 8. The test solution was placed in a thermostat for 12 hours.
After the temperature was raised to 0 ° C., the leaves of Asakusanori, which had been infected with the pot-shaped fungus and had a leaf length of about 3 cm, were immersed in each solution for 5 minutes for immersion treatment. After the immersion treatment, the glue leaves were thoroughly washed with clean seawater to remove the test solution, and then stored in a glass petri dish with a diameter of 10 cm filled with 30 ml of clean seawater for each of the test plots. The culture was allowed to stand for 7 days in a 15 ° C. constant temperature culture tank under illumination for 10 hours.

After completion of the culture, the lamina was observed under a microscope.
The control effect was determined by confirming the survival and death of the pot-shaped fungi and the degree of damage to the laver leaves by the test solution. In addition, isonicotinic acid hydrazide (manufactured by Wako Pure Chemical Industries, Ltd.) and 2-mercaptopyridine N-oxide (manufactured by Aldrich) were used as comparative compounds. A section in which the test solution was only seawater was used as an untreated control section.

Table 8 shows the results.

[0060]

[Table 8]

A complete bactericidal effect on jars was observed with a solution of cetylpyridinium bromide monohydrate at a concentration of 2 ppm or more. However, in the case of a solution of 32 ppm or more, damage to the laver leaves is observed. On the other hand, other pyridine compounds such as isonicotinic acid hydrazide and 2-mercaptopyridine
With N-oxide, a bactericidal effect was not observed.

[0062]

According to the present invention, it is possible to provide a controlling method and a controlling agent which are effective for diseases caused on cultured paste, especially for fungus and scab disease.

Claims (20)

(57) [Claims] 1. A compound of the general formula (I) [Wherein R ¹ , R ² and R ³ are the same or different and are hydrogen, linear or branched alkyl having 1 to 30 carbons, or linear or branched substituted alkyl having 1 to 30 carbons (the substituted The alkyl substituents may be the same or different
1-3 halogen, hydroxy, aryl, alkyl
Substituted aryl, amino, alkyl substituted amino, alkoxy
Si, alkanoyl, aroyl, alkoxycarbonyl
Other indicates a is) aryloxycarbonyl, X ^- is pyridinium salt or a hydrate thereof represented by represents an anion] (hereinafter, laver disease control agent containing collectively referred to as pyridinium salts) as an active ingredient, Nori disease preventive or Nori activator. 2. The agent for controlling pest disease according to claim 1,
Ri disease prevention agent. 3. The glue activator according to claim 1. 4. The method according to claim 1, wherein the anion is a halogen ion.
2. The glue disease controlling agent or the glue disease preventing agent according to 2. 5. The method according to claim 1, wherein the anion is a halogen ion.
3. The glue activator according to 3. 6. The method according to claim 2, further comprising a chelating agent.
Or the glue disease controlling agent or the glue disease preventing agent according to 4. 7. The method according to claim 3, further comprising a chelating agent.
Norikatsu activators of other 5 wherein. 8. The method according to claim 2, further comprising an acid.
A Nori disease controlling agent or Nori disease preventing agent according to any of the above. 9. The method according to claim 3, further comprising an acid.
A glue activator according to any of the above. 10. The method of claim 1 wherein the glue disease is a pot-like fungus or a scab.
Claims 2, 4, 6, which are disease, green spot or filamentous bacteriosis.
8. A glue disease controlling agent or glue disease prevention according to any one of 8.
Agent. (11) A pyridinium salt according to (1).
Immerse the glue in an aqueous solution containing
Nori disease control method characterized by spraying on Nori, Nori
A disease prevention method or a glue activation method. (12) A pyridinium salt according to (1).
Immerse the glue in an aqueous solution containing
Nori disease control method characterized by spraying on Nori or
Is the Nori disease prevention method. (13) A pyridinium salt according to the above (1).
Immerse the glue in an aqueous solution containing
A method for activating glue, which is sprayed on glue. 14. The method of claim 1 wherein the glue disease is a swelling fungus disease or a germ disease.
13. The method according to claim 12, wherein the disease is a disease, green spot disease or filamentous bacteriosis.
A method for controlling the disease of Nori or the method of preventing Nori disease. 15. The concentration of pyridinium salts is from 1 to 100.
15. The method according to claim 11, wherein the amount is 0 ppm.
Law. 16. The processing time of pyridinium salts is from 1 second to
The method according to any one of claims 11 to 15, which is for one hour. 17. The method according to claim 17, wherein the pyridinium salt is cetylpyridinium.
The glue disease prevention according to claim 2, which is muchloride monohydrate.
Remover or Nori disease prevention agent. 18. The method according to claim 18, wherein the pyridinium salt is cetylpyridinium.
4. Nori activation according to claim 3, which is muchloride monohydrate.
Agent. 19. The method according to claim 19, wherein the pyridinium salt is octylpyridini.
3. The glue disease controlling agent according to claim 2, which is um chloride.
Or Nori disease prevention agent. (20) the pyridinium salt is octylpyridini;
The glue activator according to claim 3, which is um chloride.