JP2022167493A - Composition including two kinds of polyglyceryl fatty acid ester and hyaluronic acid - Google Patents

Abstract

To provide a composition that is transparent or slightly translucent even in the case where a composition includes a combination of a hyaluronic acid component and two classes of polyglyceryl fatty acid ester.SOLUTION: The present invention relates to a composition containing (a) at least one kind of optionally selected oil, (b) at least one kind of first polyglyceryl fatty acid ester having an HLB value of more than 11.0, (c) at least one kind of second polyglyceryl fatty acid ester having an HLB value of less than 11.0, (d) at least one kind of hyaluronic acid component, (e) at least one kind of polyol having five or more carbon atoms, and (f) water under several specific conditions, where the composition includes a continuous phase and a dispersion phase, and the dispersion phase has a size of 300nm or less, preferably 200nm or less, and more preferably 100nm or less. The composition according to the present invention can have turbidity of 50 NTU or less, preferably 30 NTU or less, and more preferably 10 NTU or less.SELECTED DRAWING: None

Description

The present invention relates to compositions, preferably cosmetic or dermatological compositions, comprising at least two different types of polyglyceryl fatty acid esters.

Oil-in-water (O/W) or water-in-oil (W/O) emulsions are used in the field of cosmetics and dermatology, especially for the preparation of cosmetics such as emulsions, creams, tonics, serums or toners. It is well known as

In particular, fine emulsions, such as O/W nano- or microemulsions, are of particular interest in cosmetics due to their transparent or slightly translucent appearance.

On the other hand, compositions containing polyglyceryl fatty acid esters are known in the fields of cosmetics and dermatology. Polyglyceryl fatty acid esters can function as surfactants and are therefore typically used for preparing emulsions such as oil-in-water (O/W) or water-in-oil (W/O) emulsions. can be used for Polyglyceryl fatty acid esters are preferred for environmental reasons such as low environmental load compared to polyoxyethylene surfactants.

WO2020/110716 discloses a composition in the form of a nano- or microemulsion comprising two polyglyceryl fatty acid esters with a transparent or slightly translucent appearance.

On the other hand, hyaluronic acid components such as sodium hyaluronate are known to provide moisturizing benefits.

WO 2020/110716 pamphlet

Walter Noll, Chemistry and Technology of Silicones (1968), Academic Press Cosmetics and Toiletries, Vol. 91, Jan. 76, pp. 27-32, Todd & Byers, Volatile Silicone Fluids for Cosmetics Satoshi Tomomasa et al., Oil Chemistry, Vol. 37, No. 11 (1988), pp. 48-53.

However, compositions containing two classes of polyglyceryl fatty acid esters, such as those disclosed in WO 2020/110716, tend not to be transparent or slightly translucent, so the inclusion of a hyaluronic acid component is discouraged. proved difficult.

It is an object of the present invention to provide a composition that is transparent or slightly translucent even when the composition comprises a combination of hyaluronic acid component and two classes of polyglyceryl fatty acid esters.

The above objects of the present invention are
(a) at least one optional oil;
(b) at least one first polyglyceryl fatty acid ester having an HLB value greater than 11.0, preferably greater than 12.0, more preferably greater than 13.0;
(c) at least one second polyglyceryl fatty acid ester having an HLB value of less than 11.0, preferably less than 10.0, more preferably less than 9.0;
(d) at least one hyaluronic acid component selected from the group consisting of hyaluronic acid, hyaluronic acid salts, hyaluronic acid derivatives, hyaluronic acid derivative salts, and mixtures thereof;
(e) at least one polyol having 5 or more carbon atoms, and
(f) a composition comprising water,
The total amount of (b) the first polyglyceryl fatty acid ester and (c) the second polyglyceryl fatty acid ester is 0.01% by mass to 5% by mass relative to the total amount of the composition,
The mass ratio of ((a) amount of oil)/(total amount of (b) first polyglyceryl fatty acid ester and (c) second polyglyceryl fatty acid ester) is less than 0.3;
The mass ratio of ((c) the amount of the second polyglyceryl fatty acid ester)/((b) the amount of the first polyglyceryl fatty acid ester) is more than 0.01 and less than 0.2,
The mass ratio of ((e) amount of polyol having 5 or more carbon atoms)/(total amount of (b) first polyglyceryl fatty acid ester and (c) second polyglyceryl fatty acid ester) is more than 0.1 to 5 is less than
The composition comprises a continuous phase and a dispersed phase, the dispersed phase having a size of 300 nm or less, preferably 200 nm or less, more preferably 100 nm or less.
It can be achieved by a composition.

(a) the oil may be selected from polar oils;

The amount of (a) oil in the composition according to the invention may be less than 0.7% by weight, preferably less than 0.6% by weight, more preferably less than 0.5% by weight, relative to the total weight of the composition.

(b) The first polyglyceryl fatty acid ester may contain 2 to 4 glycerol units, preferably 3 or 4 glycerol units, more preferably 4 glycerol units.

(b) The fatty acid portion of the first polyglyceryl fatty acid ester may contain 12 or fewer carbon atoms, preferably 11 or fewer carbon atoms, more preferably 10 or fewer carbon atoms.

The amount of (b) the first polyglyceryl fatty acid ester in the composition according to the invention is 0.01% to 5% by weight, preferably 0.1% to 4% by weight, more preferably 0.1% to 4% by weight, relative to the total weight of the composition. It may be 1% by mass to 3% by mass.

(c) The second polyglyceryl fatty acid ester may contain 2 to 4 glycerol units, preferably 2 or 3 glycerol units, more preferably 2 glycerol units.

(c) The fatty acid portion of the second polyglyceryl fatty acid ester may contain 14 or more carbon atoms, preferably 16 or more carbon atoms, more preferably 18 or more carbon atoms.

The amount of (c) the second polyglyceryl fatty acid ester in the composition according to the invention is 0.001% to 0.5% by weight, preferably 0.01% to 0.4% by weight, more preferably 0.01% to 0.4% by weight, relative to the total weight of the composition. It may be 0.1% by mass to 0.3% by mass.

(d) The hyaluronic acid component can be selected from hyaluronic acid, hydrolyzed hyaluronic acid, acetylated hyaluronic acid, cationic hyaluronic acid, salts thereof, and mixtures thereof.

The amount of (d) hyaluronic acid component in the composition according to the invention is 0.001% to 5% by weight, preferably 0.01% to 4% by weight, more preferably 0.1% by weight, relative to the total weight of the composition. It may be up to 3% by mass.

(e) polyols having 5 or more carbon atoms are selected from diols having ₅ or more carbon atoms, preferably C5 _- C10 diols, more preferably pentylene glycol, hexylene glycol, and mixtures thereof can do.

The amount of (e) polyol having 5 or more carbon atoms in the composition according to the invention is 0.01% to 7% by weight, preferably 0.1% to 6% by weight, relative to the total weight of the composition, More preferably, it may be in the range of 1% by mass to 5% by mass.

The present invention also relates to a cosmetic method for treating keratinous material, comprising applying a composition according to the invention to the keratinous material.

After extensive investigation, the present inventors have provided a composition that is transparent or slightly translucent even when the composition comprises a combination of hyaluronic acid or a salt thereof and two classes of polyglyceryl fatty acid esters. I discovered that it can be done.

Accordingly, one aspect of the present invention is
(a) at least one optional oil;
(b) at least one first polyglyceryl fatty acid ester having an HLB value greater than 11.0, preferably greater than 12.0, more preferably greater than 13.0;
(c) at least one second polyglyceryl fatty acid ester having an HLB value of less than 11.0, preferably less than 10.0, more preferably less than 9.0;
(d) at least one hyaluronic acid component selected from the group consisting of hyaluronic acid, hyaluronic acid salts, hyaluronic acid derivatives, hyaluronic acid derivative salts, and mixtures thereof;
(e) at least one polyol having 5 or more carbon atoms, and
(f) a composition comprising water,
The total amount of (b) the first polyglyceryl fatty acid ester and (c) the second polyglyceryl fatty acid ester is 0.01% by mass to 5% by mass relative to the total amount of the composition,
The mass ratio of ((a) amount of oil)/(total amount of (b) first polyglyceryl fatty acid ester and (c) second polyglyceryl fatty acid ester) is less than 0.3;
The mass ratio of ((c) the amount of the second polyglyceryl fatty acid ester)/((b) the amount of the first polyglyceryl fatty acid ester) is more than 0.01 and less than 0.2,
The mass ratio of ((e) amount of polyol having 5 or more carbon atoms)/(total amount of (b) first polyglyceryl fatty acid ester and (c) second polyglyceryl fatty acid ester) is more than 0.1 to 5 is less than
The composition comprises a continuous phase and a dispersed phase, the dispersed phase having a size of 300 nm or less, preferably 200 nm or less, more preferably 100 nm or less.
composition.

Due to the small size of the dispersed phase, the compositions according to the invention can be transparent or slightly translucent. The composition according to the invention may have a turbidity of 50 NTU or less, preferably 30 NTU or less, more preferably 10 NTU or less.

If the composition according to the invention contains oil, it may be in the form of a nano- or microemulsion, although it contains hyaluronic acid or its salts.

The surfactant system used in the composition according to the invention is
at least one first polyglyceryl fatty acid ester having a higher HLB value;
It may be characterized by a combination with at least one second polyglyceryl fatty acid ester having a lower HLB value.

A higher HLB value of the first polyglyceryl fatty acid ester can belong to a higher HLB numerical range,
The lower HLB value of the second polyglyceryl fatty acid ester can belong to the lower HLB numerical range,
and,
Higher HLB numerical ranges and lower HLB numerical ranges do not overlap each other.

The compositions according to the invention can be less sticky, thus reducing the sticky feel. Therefore, the composition according to the invention can provide an excellent feel in use, in particular an excellent skin feel after application of the composition.

The term "sticky" is used herein to mean the property of imparting a sticky feel to the skin.

Compositions according to the invention can be prepared without the use of large amounts of energy, such as those required by homogenizers. Thus, compositions according to the invention can be prepared by using small amounts of energy, such as by gently stirring the components of the composition together. Therefore, the composition according to the invention may be environmentally friendly in view of its method of preparation.

The compositions according to the invention are described in more detail below.

[oil]
The composition according to the invention may comprise (a) at least one oil. When two or more oils are used, they may be the same or different.

As used herein, "oil" means a fatty compound or substance that is in liquid or paste (non-solid) form at room temperature (25° C.) under atmospheric pressure (760 mmHg). As oils, those commonly used in cosmetics can be used, alone or in combination. These oils may be volatile or non-volatile.

(a) The oils may be non-polar oils such as hydrocarbon oils or silicone oils, polar oils such as vegetable or animal oils, and ester or ether oils, or mixtures thereof.

(a) Oils may be selected from the group consisting of oils of plant or animal origin, synthetic oils, silicone oils, hydrocarbon oils, and fatty alcohols.

Examples of vegetable oils include, for example, linseed oil, camellia oil, macadamia nut oil, corn oil, mink oil, olive oil, avocado oil, sasanqua oil, castor oil, safflower oil, jojoba oil, sunflower oil, almond oil, rapeseed oil, sesame oil, Mention may be made of soybean oil, peanut oil, and mixtures thereof.

Examples of animal oils include, for example, squalene and squalane.

Examples of synthetic oils include alkane oils such as isododecane and isohexadecane, ester oils, ether oils, and artificial triglycerides.

The ester oils are preferably saturated or unsaturated linear or branched C ₁ -C ₂₆ aliphatic monoacids or polyacids and saturated or unsaturated linear or branched C ₁ -C ₂₆ Liquid esters with aliphatic monohydric alcohols or polyhydric alcohols, the total number of carbon atoms in these esters being 10 or more.

Preferably, in the case of esters of monohydric alcohols, at least one of the alcohols and acids from which the esters of the invention are derived is branched.

Among the monoesters of monoacids with monohydric alcohols: ethyl palmitate, ethylhexyl palmitate, isopropyl palmitate, dicaprylyl carbonate, alkyl myristates, such as isopropyl myristate or ethyl myristate, isocetyl stearate, 2-ethylhexyl isononanoate , isononyl isononanoate, isodecyl neopentanoate, and isostearyl neopentanoate.

Esters of _{C4 - C22} dicarboxylic or tricarboxylic acids with C1- _C22 alcohols, and mono-, di- or tricarboxylic acids with non-sugar _C4 - _C26 dihydroxy, trihydroxy, tetrahydroxy, or Esters with pentahydroxy alcohols can also be used.

Among others, the following may be mentioned: diethyl sebacate, isopropyl lauroylsarcosine, diisopropyl sebacate, bis(2-ethylhexyl) sebacate, diisopropyl adipate, di-n-propyl adipate, dioctyl adipate, bis( 2-ethylhexyl), diisostearyl adipate, bis(2-ethylhexyl) maleate, triisopropyl citrate, triisocetyl citrate, triisostearyl citrate, glyceryl trilactate, glyceryl trioctanoate, trioctyldodecyl citrate, citric acid Trioleyl acid, neopentyl glycol diheptanoate, diethylene glycol diisononanoate.

As ester oils sugar esters and diesters of C ₆ -C ₃₀ , preferably C ₁₂ -C ₂₂ fatty acids can be used. The term "sugar" means an oxygen-bearing hydrocarbon-based compound containing some alcohol functionality, with or without an aldehyde or ketone functionality, and containing at least 4 carbon atoms. Recall that These sugars may be monosaccharides, oligosaccharides, or polysaccharides.

Examples of suitable sugars that may be mentioned include alkyl sugars such as sucrose (or saccharose), glucose, galactose, ribose, fucose, maltose, fructose, mannose, arabinose, xylose and lactose and derivatives thereof, especially the methyl derivative. Derivatives, such as methyl glucose, are included.

Sugar esters of fatty acids are inter alia a group comprising esters or mixtures of esters of the aforementioned sugars with linear or branched, saturated or unsaturated C ₆ -C ₃₀ , preferably C ₁₂ -C ₂₂ fatty acids. You can choose from These compounds, if unsaturated, can have 1 to 3 conjugated or non-conjugated carbon-carbon double bonds.

Esters according to this variant can also be selected from monoesters, diesters, triesters, tetraesters and polyesters, and mixtures thereof.

These esters are, for example, oleates, laurates, palmitates, myristates, behenates, coconut fatty acid esters, stearates, linoleates, linolenates, caprates, and arachidonic acid esters. Esters, or mixtures thereof, such as mixed esters of oleopalmitic acid, oleostearic acid and palmitostearic acid, and pentaerythrityl tetraethylhexanoate, among others.

More particularly, mono- and diesters, especially monooleate or dioleate esters of sucrose, glucose or methylglucose, stearates, behenates, oleopalmitates, linoleates, linolenates, and An oleostearate is used.

An example that may be mentioned is the product sold under the name Glucate® DO by the company Amerchol, which is methylglucose dioleate.

Examples of preferred ester oils include diisopropyl adipate, dioctyl adipate, 2-ethylhexyl hexanoate, ethyl laurate, cetyl octanoate, octyldodecyl octanoate, isodecyl neopentanoate, myristyl propionate, 2-ethylhexanoate. -ethylhexyl, 2-ethylhexyl octanoate, 2-ethylhexyl caprylate/caprate, methyl palmitate, ethyl palmitate, isopropyl palmitate, dicaprylyl carbonate, isopropyl lauroyl sarcosine, isononyl isononanoate, ethylhexyl palmitate, isohexyl laurate, laurin Hexyl acid, isocetyl stearate, isopropyl isostearate, isopropyl myristate, isodecyl oleate, glyceryl tri(2-ethylhexanoate), pentaerythrityl tetra(2-ethylhexanoate), 2-ethylhexyl succinate, diethyl sebacate , and mixtures thereof.

Examples of artificial triglycerides include, for example, caprylic caprylyl glyceride, glyceryl trimyristate, glyceryl tripalmitate, glyceryl trilinolenate, glyceryl trilaurate, glyceryl tricaprate, glyceryl tricaprylate, tri(capric/caprylic)glyceryl, and tri(capric/caprylic/linolenic)glyceryl.

Examples of silicone oils include linear organopolysiloxanes such as dimethylpolysiloxane, methylphenylpolysiloxane, and methylhydrogenpolysiloxane, cyclic organopolysiloxanes such as cyclohexasiloxane, octamethylcyclotetrasiloxane, and the like. , decamethylcyclopentasiloxane, and dodecamethylcyclohexasiloxane, and mixtures thereof.

Preferably, the silicone oil is selected from liquid polydialkylsiloxanes, especially liquid polydimethylsiloxanes (PDMS), and liquid polyorganosiloxanes containing at least one aryl group.

These silicone oils may also be organically modified. Organomodified silicones that can be used according to the invention are silicone oils as defined above, which contain in their structure one or more organic functional groups bonded via hydrocarbon-based groups.

Organopolysiloxanes are defined in more detail in Walter Noll, Chemistry and Technology of Silicones (1968), Academic Press. Organopolysiloxanes may be volatile or nonvolatile.

If volatile, the silicone is more particularly selected from those having a boiling point between 60° C. and 260° C., even more particularly selected from:
(i) cyclic polydialkylsiloxanes containing 3 to 7, preferably 4 to 5, silicon atoms; These are, for example, octamethylcyclotetrasiloxane, sold inter alia under the name Volatile Silicone® 7207 by the company Union Carbide or sold under the name Silbione® 70045 V2 by the company Rhodia, the company Union Carbide under the name Volatile Silicone® 7158 by Rhodia, decamethylcyclopentasiloxane sold under the name Silbione® 70045 V5 by Rhodia, and under the name Silsoft 1217 by Momentive Performance Materials dodecamethylcyclopentasiloxane, and mixtures thereof. Mention may also be made of cyclocopolymers of the type dimethylsiloxane/methylalkylsiloxane of the formula, such as Silicone Volatile® FZ 3109 sold by Union Carbide.

Mixtures of cyclic polydialkylsiloxanes and organosilicon compounds, such as mixtures of octamethylcyclotetrasiloxane and tetratrimethylsilylpentaerythritol (50/50), and octamethylcyclotetrasiloxane and oxy-1,1'-bis(2 ,2,2′,2′,3,3′-Hexatrimethylsilyloxy)neopentane may also be mentioned: and
(ii) a linear volatile polydialkylsiloxane containing from 2 to 9 silicon atoms and having a viscosity at 25° C. of 5×10 ⁻⁶ m ² /s or less; An example is the decamethyltetrasiloxane sold especially under the name SH 200 by the company Toray Silicone. Silicones belonging to this category are also described in an article published in Cosmetics and Toiletries, Vol. 91, Jan. 76, pp. 27-32, Todd & Byers, Volatile Silicone Fluids for Cosmetics. Viscosity of silicones is measured at 25° C. according to ASTM Standard 445, Annex C.

Nonvolatile polydialkylsiloxanes may also be used. These non-volatile silicones are more particularly selected from polydialkylsiloxanes, among which polydimethylsiloxanes having predominantly trimethylsilyl end groups may be mentioned.

Among these polydialkylsiloxanes the following commercial products may be mentioned without limitation:
- 47 and 70 047 series of Silbione® oils sold by Rhodia or Mirasil® oils, such as 70 047 V 500 000 oil,
- the Mirasil® series of oils sold by Rhodia,
- Dow Corning 200 series oils, e.g. DC200 with a viscosity of ^60000mm2 /s, and
- Viscasil® oils from General Electric and certain oils from the SF series from General Electric (SF 96, SF 18).

Mention may also be made of polydimethylsiloxanes containing dimethylsilanol end groups, known by the name dimethiconol (CTFA), such as the 48 series oils from Rhodia.

Among the silicones containing aryl groups, mention may be made of polydiarylsiloxanes, especially polydiphenylsiloxanes and polyalkylarylsiloxanes such as phenylsilicone oils.

Phenyl silicone oil has the following formula:

[In the formula,
R ₁ to R ₁₀ are each independently a saturated or unsaturated, linear, cyclic or branched C ₁ to C ₃₀ hydrocarbon group, preferably a C ₁ to C ₁₂ hydrocarbon group, more preferably a C ₁ to C ₆ hydrocarbon group, especially a methyl, ethyl, propyl or butyl group,
m, n, p, and q are each independently an integer of 0 to 900 inclusive, preferably 0 to 500 inclusive, more preferably 0 to 100 inclusive;
However, the sum of n+m+q is non-zero]
of phenyl silicones.

Examples that may be mentioned include products marketed under the following names:
- 70 641 series of Silbione® oils from Rhodia,
- Rhodorsil® 70 633 and 763 series oils from Rhodia,
- Dow Corning 556 Cosmetic Grade Fluid, an oil manufactured by Dow Corning,
- Bayer PK series silicones, e.g. PK20 products,
- Certain oils from the SF series manufactured by General Electric, such as SF 1023, SF 1154, SF 1250 and SF 1265.

Phenyl trimethicone (wherein R ₁ to R ₁₀ are methyl, p, q, and n=0 and m=1) is preferred as the phenyl silicone oil.

Organically modified liquid silicones may contain polyethyleneoxy and/or polypropyleneoxy groups, among others. Thus, mention may be made of the silicone KF-6017 proposed by Shin-Etsu Chemical Co., Ltd., and the oils Silwet® L722 and L77 from Union Carbide.

Hydrocarbon oils can be chosen from:
- C6 _{- C16} lower alkanes, linear or branched, optionally cyclic. Examples that may be mentioned include hexane, undecane, dodecane, tridecane and isoparaffins, such as isohexadecane, isododecane and isodecane: and
- straight or branched hydrocarbons containing more than 16 carbon atoms, such as liquid paraffin, liquid petroleum jelly, polydecene and hydrogenated polyisobutene, such as Parleam®, and squalane.

Preferred examples of hydrocarbon oils include linear or branched hydrocarbons such as isohexadecane, isododecane, squalane, mineral oils (e.g. liquid paraffin), paraffin, vaseline or petrolatum, and naphthalenes. Mention may be made of loaded polyisobutene, isoeicosane, and decene/butene copolymers, and mixtures thereof.

The term "aliphatic" in fatty alcohols means containing a relatively large number of carbon atoms. Thus alcohols with 4 or more, preferably 6 or more, more preferably 12 or more carbon atoms are included within the scope of fatty alcohols. Fatty alcohols may be saturated or unsaturated. Fatty alcohols may be linear or branched.

Aliphatic alcohols have the structure R-OH [wherein R contains 4 to 40 carbon atoms, preferably 6 to 30 carbon atoms, more preferably 12 to 20 carbon atoms, saturated and selected from unsaturated, linear and branched groups]. In at least one embodiment, R can be selected from C ₁₂ -C ₂₀ alkyl groups and C ₁₂ -C ₂₀ alkenyl groups. R may or may not be substituted with at least one hydroxyl group.

Examples of fatty alcohols include lauryl alcohol, cetyl alcohol, stearyl alcohol, isostearyl alcohol, behenyl alcohol, undecylenyl alcohol, myristyl alcohol, octyldodecanol, hexyldecanol, oleyl alcohol, linoleyl alcohol, palmitoleyl alcohol, arachidonyl alcohol. , erucyl alcohol, and mixtures thereof.

Preferably, the fatty alcohol is a saturated fatty alcohol.

Accordingly, fatty alcohols are linear or branched saturated or unsaturated C ₆ -C ₃₀ alcohols, preferably linear or branched saturated C ₆ -C ₃₀ alcohols, more preferably linear or branched saturated C ₁₂ -C ₂₀ alcohols.

The term "saturated fatty alcohol" is used herein to refer to alcohols having long fatty saturated carbon chains. The saturated fatty alcohol is preferably selected from any linear or branched, saturated C6 _{- C30} fatty alcohol. Among the linear or branched saturated C ₆ -C ₃₀ fatty alcohols, the linear or branched saturated C ₁₂ -C ₂₀ fatty alcohols can preferably be used. Any linear or branched saturated C ₁₆ -C ₂₀ fatty alcohol can more preferably be used. Branched C ₁₆ -C ₂₀ fatty alcohols can be used even more preferably.

Examples of saturated fatty alcohols include lauryl alcohol, cetyl alcohol, stearyl alcohol, isostearyl alcohol, behenyl alcohol, undecylenyl alcohol, myristyl alcohol, octyldodecanol, hexyldecanol, and mixtures thereof. In one embodiment, cetyl alcohol, stearyl alcohol, octyldodecanol, hexyldecanol, or mixtures thereof (eg, cetearyl alcohol) and behenyl alcohol can be used as saturated fatty alcohols.

According to at least one embodiment, the fatty alcohol used in the composition according to the invention is preferably selected from cetyl alcohol, octyldodecanol, hexyldecanol and mixtures thereof.

It is also preferred that (a) the oil is selected from oils having a molecular weight of less than 600 g/mol.

Preferably, (a) the oil has a low molecular weight, such as less than 600 g/mol, and is an ester oil with short hydrocarbon chains (C ₁ -C ₁₂ ) (e.g. isopropyl lauroyl sarcosine, isopropyl myristate, isopropyl palmitate , isononyl isononanoate and ethylhexyl palmitate), silicone oils (e.g. volatile silicones such as cyclohexasiloxane), hydrocarbon oils (e.g. isododecane, isohexadecane and squalane), branched and/or unsaturated aliphatic It is chosen among alcohol (C ₁₂ -C ₃₀ ) type oils such as octyldodecanol and oleyl alcohol, and ether oils such as dicaprylyl ether.

(a) The oil may be chosen from polar oils, preferably ester oils, more preferably isopropyl myristate, and from non-polar oils, preferably ether oils, more preferably dicaprylyl ether.

The amount of (a) oil in the composition according to the invention may be 0.001% or more, preferably 0.01% or more, more preferably 0.1% or more, relative to the total weight of the composition.

The amount of (a) oil in the composition according to the invention may be less than 0.7% by weight, preferably less than 0.6% by weight, more preferably less than 0.5% by weight, relative to the total weight of the composition.

The amount of (a) oil in the composition according to the invention is from 0.001% to less than 0.7%, preferably from 0.01% to less than 0.6%, more preferably 0.1% by weight, relative to the total weight of the composition. It may be less than ~0.5% by mass.

[First Polyglyceryl Fatty Acid Ester]
The composition according to the present invention comprises (b) at least one first polyglyceryl fatty acid ester having an HLB value greater than 11.0, preferably greater than 12.0, more preferably greater than 13.0. Although a single type of (b) first polyglyceryl fatty acid ester may be used, two or more different types of (b) first polyglyceryl fatty acid ester may be used in combination.

(b) The first polyglyceryl fatty acid ester can function as a surfactant, especially a nonionic surfactant.

(b) The first polyglyceryl fatty acid ester may have an HLB value of greater than 11.0 to 17.0, preferably greater than 12.0 to 16.0, more preferably greater than 13.0 to 15.0.

The term HLB ("hydrophilic-lipophilic balance") is well known to those skilled in the art and describes the ratio between hydrophilic and lipophilic sites in a molecule.

When two or more (b) first polyglyceryl fatty acid esters are used, the HLB value is determined by a weighted average of the HLB values of all the (b) first polyglyceryl fatty acid esters.

(b) The first polyglyceryl fatty acid ester can be selected from mono-, di-, tri- and higher esters of saturated or unsaturated fatty acids.

(b) The first polyglyceryl fatty acid ester preferably contains 2 to 4 glycerol units, preferably 3 or 4 glycerol units, more preferably 4 glycerol units.

(b) the fatty acid or fatty acid moiety for the fatty acid portion of the first polyglyceryl fatty acid ester may contain 12 or fewer carbon atoms, preferably 11 or fewer carbon atoms, more preferably 10 or fewer carbon atoms . (b) the fatty acid or fatty acid moiety for the fatty acid moiety of the first polyglyceryl fatty acid ester may contain 4 or more carbon atoms, preferably 6 or more carbon atoms, more preferably 8 or more carbon atoms . (b) the fatty acid or fatty acid moiety for the fatty acid moiety of the first polyglyceryl fatty acid ester has 4 to 12 carbon atoms, preferably 6 to 11 carbon atoms, more preferably 8 to 10 carbon atoms; good too.

(b) The fatty acid for the fatty acid portion of the first polyglyceryl fatty acid ester may be saturated or unsaturated and may be selected from caprylic acid, capric acid, and lauric acid.

(b) the first polyglyceryl fatty acid ester is PG3 caprate (HLB: about 14), PG4 caprylate (HLB: 14), PG4 laurate (HLB: about 14), PG4 caprate (HLB: 14), myristin Acid PG5 (HLB: 15.4), stearic acid PG5 (HLB: 15), caprylic acid PG6 (HLB: 14.6), capric acid PG6 (HLB: 13.1), lauric acid PG6 (HLB: 14.1), lauric acid PG10 (HLB: 15.2), PG10 myristate (HLB: 14.9), PG10 stearate (HLB: 14.1), PG10 isostearate (HLB: 13.7), PG10 oleate (HLB: 13.0), PG10 coconut fatty acid (HLB: 16), and these can be selected from the group consisting of mixtures of

(b) the first polyglyceryl fatty acid ester is PG3 caprate (HLB: about 14), PG4 caprylate (HLB: 14), PG4 laurate (HLB: about 14), PG4 caprate (HLB: 14), and It may be preferred to select from the group consisting of mixtures of these.

The amount of (b) the first polyglyceryl fatty acid ester in the composition according to the present invention is 0.01% by mass or more, preferably 0.1% by mass or more, more preferably 1% by mass or more, relative to the total mass of the composition. may

On the other hand, the amount of (b) the first polyglyceryl fatty acid ester in the composition according to the present invention is 5% by mass or less, preferably 4% by mass or less, more preferably 3% by mass or less, relative to the total mass of the composition. may be

The amount of (b) the first polyglyceryl fatty acid ester in the composition according to the invention is 0.01% to 5% by weight, preferably 0.1% to 4% by weight, more preferably 0.1% to 4% by weight, relative to the total weight of the composition. It may be in the range of 1% by mass to 3% by mass.

[Second Polyglyceryl Fatty Acid Ester]
The composition according to the invention comprises (c) at least one second polyglyceryl fatty acid ester having an HLB value of less than 11.0, preferably less than 10.0, more preferably less than 9.0. Although a single type of (c) second polyglyceryl fatty acid ester may be used, two or more different types of (c) second polyglyceryl fatty acid ester may be used in combination.

(c) The second polyglyceryl fatty acid ester can function as a surfactant, especially a nonionic surfactant.

(c) The second polyglyceryl fatty acid ester may have an HLB value of 5.0 to less than 11.0, preferably 6.0 to less than 10.0, more preferably 7.0 to less than 9.0.

When two or more (c) second polyglyceryl fatty acid esters are used, the HLB value is determined by the weighted average of the HLB values of all the (c) second polyglyceryl fatty acid esters.

(c) The second polyglyceryl fatty acid ester can be selected from mono-, di-, tri- and higher esters of saturated or unsaturated fatty acids.

(c) The second polyglyceryl fatty acid ester preferably contains 2 to 4 glycerol units, preferably 2 or 3 glycerol units, more preferably 2 glycerol units.

(c) the fatty acid or fatty acid moiety for the fatty acid moiety of the second polyglyceryl fatty acid ester may contain 14 or more carbon atoms, preferably 16 or more carbon atoms, more preferably 18 or more carbon atoms . (c) The fatty acid or fatty acid moiety for the fatty acid moiety of the second polyglyceryl fatty acid ester may contain 30 or fewer carbon atoms, preferably 24 or fewer carbon atoms, more preferably 20 or fewer carbon atoms. . (c) The fatty acid or fatty acid moiety for the fatty acid moiety of the second polyglyceryl fatty acid ester may have 14-30, preferably 16-24, more preferably 18-20 carbon atoms.

(c) The fatty acid for the fatty acid portion of the second polyglyceryl fatty acid ester may be saturated or unsaturated and may be selected from myristic acid, stearic acid, isostearic acid, and oleic acid.

(c) the second polyglyceryl fatty acid ester is PG2 stearate (HLB: 5.0), PG2 distearate (HLB: 4), PG2 isostearate (HLB: 8), PG2 diisostearate (HLB: 3.2), triisostearate PG2 (HLB: 3), PG2 sesquiisostearate (HLB: about 4), PG2 oleate (HLB: 8), PG2 sesquioleate (HLB: 5.3), PG3 distearate (HLB: 5), PG3 diisostearate (HLB: 5) HLB: 5), PG3 palmate fatty acid (HLB: 7), PG5 hexastearate (HLB: 4.0), PG5 trioleate (HLB: 7.0), PG10 pentaoleate (HLB: 6.4), PG2 sesquicaprylate (HLB) : about 8), PG2 capric acid (HLB: 9.5), PG2 lauric acid (HLB: 8.5), PG2 myristate (HLB: 10), PG2 isopalmitate (HLB: 9), PG4 oleic acid (HLB: 10) , PG4 stearate (HLB: 9), PG4 isostearate (HLB: 8.2), PG6 distearate (HLB: 8), PG10 distearate (HLB: about 9), PG10 tristearate (HLB: 8), diisostearate It can be selected from the group consisting of PG10 (HLB:10), PG10 triisostearate (HLB:8), PG10 tricoate fatty acid (HLB:9), and mixtures thereof.

(c) the second polyglyceryl fatty acid ester is PG2 stearate (HLB: 5.0), PG2 distearate (HLB: 4), PG2 isostearate (HLB: 8), PG2 diisostearate (HLB: 3.2), triisostearate PG2 (HLB: 3), PG2 sesquiisostearate (HLB: about 4), PG2 oleate (HLB: 8), PG2 sesquioleate (HLB: 5.3), PG3 distearate (HLB: 5), PG3 diisostearate (HLB: 5) HLB: 5), coconut fatty acid PG3 (HLB: 7), sesquicaprylic acid PG2 (HLB: about 8), capric acid PG2 (HLB: 9.5), lauric acid PG2 (HLB: 8.5), myristic acid PG2 (HLB: 10) ), PG2 isopalmitate (HLB: 9), PG4 oleate (HLB: 10), PG4 stearate (HLB: 9), PG4 isostearate (HLB: 8.2), and mixtures thereof is preferred in some cases.

The amount of (c) the second polyglyceryl fatty acid ester in the composition according to the present invention is 0.001% by mass or more, preferably 0.01% by mass or more, more preferably 0.1% by mass or more, relative to the total mass of the composition. may

On the other hand, the amount of (c) the second polyglyceryl fatty acid ester in the composition according to the present invention is 0.5% by mass or less, preferably 0.4% by mass or less, more preferably 0.3% by mass or less, relative to the total mass of the composition. may be

The amount of (c) the second polyglyceryl fatty acid ester in the composition according to the invention is 0.001% to 0.5% by weight, preferably 0.01% to 0.4% by weight, more preferably 0.01% to 0.4% by weight, relative to the total weight of the composition. It may be in the range of 0.1% by mass to 0.3% by mass.

[Hyaluronic acid component]
The composition according to the present invention comprises (d) at least one hyaluronic acid component selected from the group consisting of hyaluronic acid, hyaluronic acid salts, hyaluronic acid derivatives, hyaluronic acid derivative salts, and mixtures thereof. A single type of hyaluronic acid component may be used, or two or more different types of hyaluronic acid components may be used in combination.

Hyaluronic acid is the predominant glucosaminoglycan found in skin. Thus, fibroblasts predominantly synthesize collagen, matrix glycoproteins other than collagen (fibronectin, laminin), proteoglycans, and elastin. As keratinocytes, they predominantly synthesize sulfated glycosaminoglycans and hyaluronic acid. Hyaluronic acid is also called hyaluronan.

Hyaluronic acid exists in a free state in the epidermis and dermis and controls the plumpness of the skin. This polysaccharide can actually hold large volumes of water, up to 1000 times its mass. In this sense, hyaluronic acid plays an important role in increasing the amount of water bound in tissues and also in the mechanical properties and wrinkling of the skin.

Hyaluronic acid can be represented by the following chemical formula.

In the context of the present invention, the term "hyaluronic acid" in particular encompasses the building blocks of hyaluronic acid of the formula:

It is the smallest fraction of hyaluronic acid, containing disaccharide dimers, D-glucuronic acid and N-acetylglucosamine.

Hyaluronic acid derivatives can be selected from the group consisting of hydrolyzed hyaluronic acid, acetylated hyaluronic acid, cationic hyaluronic acid, and mixtures thereof.

Cationic hyaluronic acid comprises at least one cationic moiety. The cationic moiety may be a trialkylammonium group such as -N ⁺ (CH ₃ ) ₃ . The cationic moiety may contain at least one hydroxyl group. Examples of cationic groups include _-CH2 -CH(OH) _-CH2 -N ⁺ ( _CH3 ) ₃ .

Examples of cationic hyaluronic acids include hydroxypropyltrimonium hyaluronate.

Hyaluronic acid salts or hyaluronic acid derivative salts include alkali metal salts such as sodium and potassium salts, alkaline earth metal salts such as magnesium salts, ammonium salts, and mixtures thereof.

The molecular weight of the hyaluronic acid component is not limited. The molecular weight of the hyaluronic acid component may be 5 kDa or higher, preferably 20 kDa or higher, more preferably 100 kDa or higher. The hyaluronic acid component may have a molecular weight of 20 MDa or less, preferably 10 MDa or less, more preferably 2,000 kDa or less. Accordingly, the molecular weight of the hyaluronic acid component may be between 5 kDa and 20 MDa, preferably between 20 kDa and 10 MDa, more preferably between 100 kDa and 2,000 kDa.

Unless otherwise defined in the description, "molecular weight" may mean number average molecular weight.

The hyaluronic acid component is in particular under the trade name CPN (MW: 10-150 kDa) by the company Hyactive, under the trade name Cristalhyal (MW: 1-1.4 MDa) by the company Soliance, and under the name Nutra HA (MW: 820 000 Da) by the company Bioland. and hyaluronic acid supplied by Bioland under the name Nutra AF (MW: 69 000 Da) and Bioland under the name Oligo HA (MW: 6100 Da).

A single hyaluronic acid component with a single molecular weight or a combination of two or more hyaluronic acid components with different molecular weights can be used.

The amount of (d) hyaluronic acid component in the composition according to the present invention may be 0.001% by weight or more, preferably 0.01% by weight or more, more preferably 0.1% by weight or more, relative to the total weight of the composition. .

The amount of (d) hyaluronic acid component in the composition according to the invention may be 5% by weight or less, preferably 4% by weight or less, more preferably 3% by weight or less, relative to the total weight of the composition. .

Therefore, the amount of (d) hyaluronic acid component in the composition according to the invention is 0.001% to 5% by weight, preferably 0.01% to 4% by weight, more preferably 0.1% by weight, relative to the total weight of the composition. It may be in the range of mass % to 3 mass %.

[Polyols having 5 or more carbon atoms]
The composition according to the invention comprises (e) at least one polyol having 5 or more carbon atoms. A single type of such polyol may be used, or two or more different types of such polyol may be used in combination.

Polyols with 5 or more carbon atoms may be selected from diols with ₅ or more carbon atoms, preferably C5 _- C10 diols, more preferably pentylene glycol, hexylene glycol, and mixtures thereof. can.

Pentylene glycol includes its isomers. Pentylene glycol is thus 1,2-pentylene glycol, 1,3-pentylene glycol, 1,4-pentylene glycol, 1,5-pentylene glycol, 2,3-pentylene glycol, and 2, It can be 4-pentylene glycol. 1,2-pentylene glycol may be preferred.

Hexylene glycol includes its isomers. Therefore, hexylene glycol is 1,2-hexylene glycol, 1,3-hexylene glycol, 1,4-hexylene glycol, 1,5-hexylene glycol, 1,6-hexylene glycol, 2,3 -hexylene glycol, 2,4-hexylene glycol, 2,5-hexylene glycol, and 2-methyl-2,4-pentanediol. 2-methyl-2,4-pentanediol may be preferred.

The amount of (e) a polyol having 5 or more carbon atoms in the composition according to the invention is at least 0.01% by weight, preferably at least 0.1% by weight, more preferably 1% by weight, relative to the total weight of the composition. or more.

On the other hand, the amount of (e) a polyol having 5 or more carbon atoms in the composition according to the invention is 7% by weight or less, preferably 6% by weight or less, more preferably 5% by weight or less, relative to the total weight of the composition. % by mass or less.

Therefore, the amount of (e) polyols having 5 or more carbon atoms in the composition according to the invention is from 0.01% to 7% by weight, preferably from 0.1% to 6% by weight, relative to the total weight of the composition. %, more preferably in the range of 1% to 5% by mass.

[water]
The composition according to the invention comprises (f) water.

The amount of (f) water in the composition according to the invention may be 50% by weight or more, preferably 60% by weight or more, more preferably 70% by weight or more, relative to the total weight of the composition.

On the other hand, the amount of (f) water in the composition according to the invention may be 95% by weight or less, preferably 90% by weight or less, more preferably 85% by weight or less, relative to the total weight of the composition. .

The amount of (f) water in the composition according to the invention is 50% to 95%, preferably 60% to 90%, more preferably 70% to 85% by weight, relative to the total weight of the composition. It may be within the range of % by mass.

[Quantitative requirements]
The total amount of (b) the first polyglyceryl fatty acid ester and (c) the second polyglyceryl fatty acid ester in the composition according to the present invention is 0.01% by mass to 5% by mass, preferably 0.02% to 4.5% by mass, more preferably 1% to 4% by mass.

The weight ratio of ((a) amount of oil)/(total amount of (b) first polyglyceryl fatty acid ester and (c) second polyglyceryl fatty acid ester) in the composition according to the invention is less than 0.3, preferably It is less than 0.2, more preferably less than 0.1.

The composition according to the invention may be free of any (a) oil. In this case, (b) the first polyglyceryl fatty acid ester and (c) the second polyglyceryl fatty acid ester may form micelles, and the micelles can form the dispersed phase in the composition according to the present invention. , (a) free of oil;

The composition according to the invention may also contain (a) an oil. In this case, (b) the first polyglyceryl fatty acid ester and (c) the second polyglyceryl fatty acid ester may form micelles, and the micelles can form the dispersed phase in the composition according to the present invention. , (a) containing oil; (a) Micelles containing oil can be thought of as "oil" droplets.

The mass ratio of ((c) the amount of the second polyglyceryl fatty acid ester)/((b) the amount of the first polyglyceryl fatty acid ester) in the composition according to the present invention is from more than 0.01 to less than 0.2, preferably from more than 0.02 to It is less than 0.19, more preferably greater than 0.03 and less than 0.18.

Weight of ((e) amount of polyol having 5 or more carbon atoms)/(total amount of (b) first polyglyceryl fatty acid ester and (c) second polyglyceryl fatty acid ester) in the composition according to the present invention The ratio is greater than 0.1 and less than 5, preferably greater than 0.15 and less than 4.5, more preferably greater than 0.2 and less than 4.0.

[Additional polyols]
The composition of the present invention may comprise at least one further polyol other than (e) the polyol having 5 or more carbon atoms. A single type of such additional polyols may be used, but two or more different types of such additional polyols may be used in combination.

The term "polyol" as used herein means an alcohol with two or more hydroxy groups and does not include sugars or derivatives thereof. Sugar derivatives include sugar alcohols obtained by reducing one or more carbonyl groups of sugars, and hydrogen atoms in one or more of their hydroxy groups are alkyl groups, hydroxyalkyl groups, alkoxy groups. , acyl groups, or sugar alcohols substituted with at least one substituent such as a carbonyl group.

The polyol may be a C ₂ -C ₄ polyol, preferably a C ₂ -C ₄ polyol containing at least 2 hydroxy groups, preferably 2-5 hydroxy groups.

Polyols may be natural polyols or synthetic polyols. Polyols can have linear, branched, or cyclic molecular structures.

Polyols can be selected from glycerin and its derivatives, and glycol and its derivatives. Polyols can be selected from the group consisting of glycerin, ethylene glycol, propylene glycol, and butylene glycol.

The amount of further polyols in the composition according to the invention may be 20% by weight or less, preferably 15% by weight or less, more preferably 10% by weight or less, relative to the total weight of the composition.

The amount of further polyols in the composition according to the invention is from 1% to 20%, preferably from 3% to 15%, more preferably from 5% to 10% by weight relative to the total weight of the composition. %.

It may be preferred that the compositions according to the invention are free of butylene glycol.

[Other ingredients]
The composition according to the invention comprises one or more monohydric alcohols, such as linear or branched monohydric alcohols containing from 1 to 6 carbon atoms, which are in liquid form at room temperature (25° C.), For example, it may contain ethanol, propanol, butanol, isopropanol, isobutanol, pentanol, and hexanol.

The amount of monohydric alcohol in the composition according to the invention may be 0.01% by weight or more, preferably 0.1% by weight or more, more preferably 1% by weight or more, relative to the total weight of the composition.

On the other hand, the amount of monohydric alcohol in the composition according to the invention may be 15% by weight or less, preferably 10% by weight or less, more preferably 5% by weight or less, relative to the total weight of the composition.

Therefore, the amount of monohydric alcohol in the composition according to the invention is from 0.01% to 15% by weight, preferably from 0.1% to 10% by weight, more preferably from 1% to 1% by weight, relative to the total weight of the composition. It may be within the range of 5% by mass.

Compositions according to the invention may also contain various adjuvants conventionally used in cosmetic and dermatological compositions, such as thickeners, anionic, nonionic, cationic and amphoteric, excluding the ingredients described above. or zwitterionic polymers, anionic, further nonionic, cationic and amphoteric surfactants, antioxidants, colorants, chelating agents, sequestering agents, fragrances, dispersants, conditioning agents, film-forming agents, preservatives, co-preservatives, and mixtures thereof.

In one embodiment, the composition according to the invention does not comprise polyglyceryl fatty acid esters containing 5 or more glycerol units, eg PG5 laurate. The term "free" here means that the compositions according to the invention may contain a limited amount of polyglyceryl fatty acid esters containing 5 or more glycerol units. However, the amount of polyglyceryl fatty acid esters containing 5 or more glycerol units should be less than 1% by weight, more preferably less than 0.1% by weight, even more preferably less than 0.01% by weight, relative to the total weight of the composition. is preferably limited to Most preferably, the composition according to the invention does not contain polyglyceryl fatty acid esters containing more than 5 glycerol units.

In another embodiment, the composition according to the invention is free of polyoxyethylene-based nonionic surfactants. The term "free" here means that the compositions according to the invention may contain limited amounts of polyoxyethylene-based nonionic surfactants. However, the amount of polyoxyethylene-based nonionic surfactant should be less than 1% by weight, more preferably less than 0.1% by weight, even more preferably less than 0.01% by weight, relative to the total weight of the composition. preferably limited. Most preferably, the compositions according to the invention are free of polyoxyethylene-based nonionic surfactants.

(preparation)
Compositions according to the present invention can be prepared by mixing the essential ingredients described above and, if necessary, the optional ingredients described above.

The method and means of mixing the above essential and optional ingredients are not limited. Any conventional method and means can be used to mix the above essential and optional ingredients to prepare the composition according to the present invention.

Compositions according to the invention can be prepared without the use of large amounts of energy, such as those required by homogenizers. Thus, compositions according to the invention can be prepared by using small amounts of energy, such as by gently stirring the components of the composition together. Therefore, the composition according to the invention is environmentally friendly in view of its preparation procedure.

[form]
Compositions according to the present invention comprise a continuous phase and a dispersed phase. The dispersed phase is dispersed in the continuous phase. Accordingly, the dispersed phase may be in the form of particles.

The continuous phase can include (f) water. The dispersed phase can comprise at least (b) a first polyglyceryl fatty acid ester and (c) a second polyglyceryl fatty acid ester. The dispersed phase may also contain (a) oil if the composition contains (a) oil. When the dispersed phase contains (a) oil, the dispersed phase can be recognized as oil droplets. When the dispersed phase (a) does not contain oil, the dispersed phase comprises (b) a first polyglyceryl fatty acid ester and (c) a second polyglyceryl fatty acid ester, the two polyglyceryl fatty acid esters forming micelles. sell.

The size of the dispersed phase is 300 nm or less, preferably 200 nm or less, more preferably 100 nm or less. Size can be measured as a volume-based average size. The size can be measured by dynamic light scattering, for example, using a dynamic light scattering particle size analyzer ELSZ-2000 (Otsuka Electronics Co., Ltd.). The minimum size of the dispersed phase is not limited, but may be 1 nm or greater, 5 nm or greater, or 10 nm or greater.

A composition according to the invention may be in the form of a nano- or microemulsion when the composition comprises (a).

A "microemulsion" can be defined in two ways, broadly and narrowly. In other words, a microemulsion refers to a thermodynamically stable, isotropic single liquid phase containing a ternary system with three components: an oily component, an aqueous component, and a surfactant (" Among the typical thermodynamically unstable emulsion systems, microemulsions also include those emulsions which, due to their smaller particle size, exhibit a transparent or slightly translucent appearance. , there is a second case (“broadly defined microemulsion”) (Satoshi Tomomasa et al., Oil Chemistry, Vol. 37, No. 11 (1988), pp. 48-53). As used herein, "microemulsion" refers to a "strictly defined microemulsion", ie, a thermodynamically stable isotropic single liquid phase.

Microemulsions are O/W (oil-in-water) microemulsions in which oil is solubilized by micelles, W/O (water-in-oil) microemulsions in which water is solubilized by reverse micelles, or surfactants. It refers to any one state of a bicontinuous microemulsion in which the number of molecular associations becomes infinite and, as a result, both the aqueous phase and the oily phase have a continuous structure.

The microemulsion may have a dispersed phase with a particle size of 100 nm or less, preferably 80 nm or less, more preferably 60 nm or less, as measured by laser particle size analysis.

By "nanoemulsion" is meant herein an emulsion characterized by a dispersed phase having a size of less than 350 nm, which optionally forms a lamellar type liquid crystalline phase at the dispersed phase/continuous phase interface. It is stabilized by a crown of nonionic surfactants (b) and (c) which can be used. In the absence of certain opacifiers, the transparency of nanoemulsions results from the small size of the dispersed phase, which is obtained through the use of mechanical energy.

Nanoemulsions can be distinguished from microemulsions by their structure. Specifically, microemulsions are thermodynamically stable dispersions formed, for example, from micelles formed by components (b) and (c) and expanded with component (a). Furthermore, microemulsions do not require substantial mechanical energy to prepare.

The nanoemulsion may have a dispersed phase with a particle size of 300 nm or less, preferably 200 nm or less, more preferably 100 nm or less, as measured by laser particle size analysis.

The compositions according to the invention are preferably in the form of O/W emulsions comprising an oily phase dispersed in a continuous aqueous phase. The dispersed oil phase can be oil droplets in the aqueous phase.

An O/W constitution or structure has an aqueous phase on the outside, since it consists of an oil phase dispersed in an aqueous phase, so that if the composition according to the invention has an O/W constitution or structure, A pleasant feel can be provided due to the immediate fresh feeling that the aqueous phase can provide.

(a) The particle size of the oil may be 100 nm or less, preferably 75 nm or less, more preferably 50 nm or less. Particle size can be measured by dynamic light scattering. Particle size measurement can be performed, for example, by a particle size analyzer ELSZ-2000 series commercially available from Otsuka Electronics Co., Ltd.

The particle size may be the volume average particle diameter or the number average particle diameter, preferably the volume average particle diameter.

The compositions according to the invention can be transparent or slightly translucent.

Transparency can be measured by measuring turbidity (for example, turbidity emits a round cell (25 mm diameter and 60 mm height) and visible light (between 400 and 800 nm, preferably 400-500 nm). (can be measured using a 2100Q (marketed by Hach Company) with a tungsten filament bulb that can be used). Measurements can be performed on the neat composition. A blank can be determined using distilled water.

A composition according to the invention may have a turbidity of 50 NTU or less, preferably 30 NTU or less, more preferably 10 NTU or less.

[Method and use]
The composition according to the invention is preferably a cosmetic or dermatological composition, preferably a cosmetic composition, more preferably a cosmetic composition for keratinous substances such as skin.

The composition according to the invention is used in non-therapeutic methods, such as cosmetic methods, for treating keratinous substances such as skin, hair, mucous membranes, nails, eyelashes, eyebrows and/or scalp by application to the keratinous substances. can do.

The invention therefore also relates to a cosmetic method for treating keratinous material, comprising the step of applying a composition according to the invention to the keratinous material.

The present invention also relates to care products, cleansing products for the skin of the body and/or face and/or mucous membranes and/or scalp and/or hair and/or nails and/or eyelashes and/or eyebrows , make-up products, make-up removal products, etc., as or in cosmetics.

In other words, the compositions according to the invention can themselves be used as cosmetics. Alternatively, the composition according to the invention can be used as an ingredient in cosmetics. For example, the composition according to the invention can be added to or combined with any other ingredient to form a cosmetic.

Care products can be lotions, creams, hair tonics, hair conditioners, sunscreens, and the like. Cleaning products can be shampoos, face washes, hand washes, and the like. Makeup products can be foundations, mascaras, lipsticks, lip glosses, blushes, eye shadows, nail varnishes, and the like. A make-up removing product can be a make-up cleanser or the like.

Since the composition according to the invention comprises at least one hyaluronic acid or salt thereof, the composition according to the invention can preferably be used for moisturizing keratinous substances such as the skin.

Another aspect of the invention is
for the production of a composition comprising a continuous phase and a dispersed phase having a size of 300 nm or less, preferably 200 nm or less, more preferably 100 nm or less,
(e) the use of at least one polyol having 5 or more carbon atoms,
The total amount of (b) the first polyglyceryl fatty acid ester and (c) the second polyglyceryl fatty acid ester is 0.01% by mass to 5% by mass relative to the total amount of the composition,
The mass ratio of ((a) amount of oil)/(total amount of (b) first polyglyceryl fatty acid ester and (c) second polyglyceryl fatty acid ester) is less than 0.3;
The mass ratio of ((c) the amount of the second polyglyceryl fatty acid ester)/((b) the amount of the first polyglyceryl fatty acid ester) is more than 0.01 and less than 0.2,
((e) amount of polyol)/(total amount of (b) first polyglyceryl fatty acid ester and (c) second polyglyceryl fatty acid ester) is more than 0.1 and less than 5,
The composition
(a) at least one optional oil;
(b) at least one first polyglyceryl fatty acid ester having an HLB value greater than 11.0, preferably greater than 12.0, more preferably greater than 13.0;
(c) at least one second polyglyceryl fatty acid ester having an HLB value of less than 11.0, preferably less than 10.0, more preferably less than 9.0;
(d) at least one hyaluronic acid component selected from the group consisting of hyaluronic acid, hyaluronic acid salts, hyaluronic acid derivatives, hyaluronic acid derivative salts, and mixtures thereof;
(f) any use, including water;

Another aspect of the invention is also a method for preparing a composition comprising a continuous phase and a dispersed phase having a size of 300 nm or less, preferably 200 nm or less, more preferably 100 nm or less, comprising:
The total amount of (b) the first polyglyceryl fatty acid ester and (c) the second polyglyceryl fatty acid ester is 0.01% by mass to 5% by mass relative to the total amount of the composition,
The mass ratio of ((a) amount of oil)/(total amount of (b) first polyglyceryl fatty acid ester and (c) second polyglyceryl fatty acid ester) is less than 0.3;
The mass ratio of ((c) the amount of the second polyglyceryl fatty acid ester)/((b) the amount of the first polyglyceryl fatty acid ester) is more than 0.01 and less than 0.2,
((e) amount of polyol)/(total amount of (b) first polyglyceryl fatty acid ester and (c) second polyglyceryl fatty acid ester) is more than 0.1 and less than 5,
(a) at least one optional oil;
(b) at least one first polyglyceryl fatty acid ester having an HLB value greater than 11.0, preferably greater than 12.0, more preferably greater than 13.0;
(c) at least one second polyglyceryl fatty acid ester having an HLB value of less than 11.0, preferably less than 10.0, more preferably less than 9.0;
(d) at least one hyaluronic acid component selected from the group consisting of hyaluronic acid, hyaluronic acid salts, hyaluronic acid derivatives, hyaluronic acid derivative salts, and mixtures thereof;
(e) at least one polyol having 5 or more carbon atoms, and
(f) It may also relate to a method comprising the step of mixing with water.

The mixing step is preferably carried out by a so-called low-energy process without special mechanical stirrers such as homogenizers that use large amounts of energy. A low energy process can be carried out by simply gently stirring components (a)-(f).

Said composition in the use and method according to the invention is preferably in the form of an O/W nano- or microemulsion when said composition comprises (a) an oil.

The present invention also provides
(e) the use of at least one polyol having 5 or more carbon atoms,
The total amount of (b) the first polyglyceryl fatty acid ester and (c) the second polyglyceryl fatty acid ester is 0.01% by mass to 5% by mass relative to the total amount of the composition,
The mass ratio of ((a) amount of oil)/(total amount of (b) first polyglyceryl fatty acid ester and (c) second polyglyceryl fatty acid ester) is less than 0.3;
The mass ratio of ((c) the amount of the second polyglyceryl fatty acid ester)/((b) the amount of the first polyglyceryl fatty acid ester) is more than 0.01 and less than 0.2,
((e) amount of polyol)/(total amount of (b) first polyglyceryl fatty acid ester and (c) second polyglyceryl fatty acid ester) is more than 0.1 and less than 5,
(a) at least one oil;
(b) at least one first polyglyceryl fatty acid ester having an HLB value greater than 11.0, preferably greater than 12.0, more preferably greater than 13.0;
(c) at least one second polyglyceryl fatty acid ester having an HLB value of less than 11.0, preferably less than 10.0, more preferably less than 9.0;
(d) at least one hyaluronic acid component selected from the group consisting of hyaluronic acid, hyaluronic acid salts, hyaluronic acid derivatives, hyaluronic acid derivative salts, and mixtures thereof;
(f) in an O/W emulsion containing water,
(a) so that the oil droplets have a particle size of 300 nm or less, preferably 200 nm or less, more preferably 100 nm or less,
It can also relate to use.

The present invention also provides
(a) at least one oil;
(b) at least one first polyglyceryl fatty acid ester having an HLB value greater than 11.0, preferably greater than 12.0, more preferably greater than 13.0;
(c) at least one second polyglyceryl fatty acid ester having an HLB value of less than 11.0, preferably less than 10.0, more preferably less than 9.0;
(d) at least one hyaluronic acid component selected from the group consisting of hyaluronic acid, hyaluronic acid salts, hyaluronic acid derivatives, hyaluronic acid derivative salts, and mixtures thereof;
(f) A method for making oil droplets in an O/W nano- or micro-emulsion containing water have a particle size of 300 nm or less, preferably 200 nm or less, more preferably 100 nm or less, comprising:
(e) at least one polyol having 5 or more carbon atoms
It also relates to a method comprising adding to an O/W nano- or micro-emulsion or using it in an O/W nano- or micro-emulsion.

The above descriptions of components (a)-(f) and optional components for the compositions according to the invention are applicable to the components for the uses and methods according to the invention. The descriptions relating to the preparation and forms of compositions according to the invention are also applicable to the preparation and forms of compositions described in the uses and methods above.

The present invention is illustrated in more detail by examples, which should not be construed as limiting the scope of the invention.

(Example 1 and Comparative Examples 1 to 3)
The following compositions shown in Table 1, according to Example 1 and Comparative Examples 1-3, were prepared by mixing the ingredients shown in Table 1. All numerical values for the amounts of ingredients given in Table 1 are based on "% by weight" of the raw material.

The compositions according to Example 1 and Comparative Examples 1-3 were in the form of O/W emulsions.

[evaluation]
(turbidity)
The turbidity of the compositions according to Example 1 and Comparative Example 2 was measured at room temperature by using a turbidity meter (2100Q portable, Hach Company).

The results are shown in Table 1 as "NTU". The lower the NTU value, the more transparent the composition.

The composition according to Example 1 was transparent or slightly translucent.

The turbidity of the compositions according to Comparative Examples 1 and 3 was not measured as the compositions were clearly opaque (not transparent or slightly translucent).

(Droplet diameter)
The size of the dispersed phase in the compositions of Example 1 and Comparative Example 2 was measured using a dynamic light scattering particle size analyzer ELSZ-2000 (Otsuka Electronics Co., Ltd.).

The size of the dispersed phase of the compositions according to Comparative Examples 1 and 3 was not measured as the compositions were clearly opaque.

Example 1 shows that using a polyol with 5 or more carbon atoms can provide a clear composition, even when the composition contains hyaluronic acid or a salt thereof.

Comparative Example 1 shows that using a polyol with less than 5 carbon atoms cannot provide a clear composition when the composition comprises hyaluronic acid or a salt thereof.

Comparative Example 2 corresponds to the formulation according to Example 1 disclosed in WO2020/110716.

Comparative Example 3 shows that the addition of hyaluronic acid or its salts to the formulation according to Example 1 disclosed in WO2020/110716 fails to provide a clear composition.

(Examples 2 to 5 and Comparative Example 4)
The following compositions shown in Table 2, according to Examples 2-5 and Comparative Example 4, were prepared by mixing the ingredients shown in Table 2. All numerical values for the amount of ingredients shown in Table 2 are based on "% by weight" of the raw material.

The compositions according to Examples 2-5 and Comparative Example 4 were in the form of O/W emulsions.

[evaluation]
(turbidity)
The turbidity of the compositions according to Examples 2-5 was measured at room temperature by using a turbidity meter (2100Q portable, Hach Company).

The results are shown in Table 2 as "NTU". The lower the NTU value, the more transparent the composition.

The compositions according to Examples 2-5 were transparent or slightly translucent.

The NTU value of the composition according to Comparative Example 4 was not tested as the composition was opaque.

(Droplet diameter)
The size of the dispersed phase in the compositions of Examples 2-5 and Comparative Example 4 was measured using a dynamic light scattering particle size analyzer ELSZ-2000 (Otsuka Electronics Co., Ltd.).

Table 2 shows the results.

The droplet size of the dispersed phase in the composition according to Comparative Example 4 was not tested because the composition was opaque.

Examples 2-5 show that the total amount of a first polyglyceryl fatty acid ester having an HLB value of greater than 11.0 and a second polyglyceryl fatty acid ester having an HLB value of less than 11.0 in the composition is added to the total weight of the composition. On the other hand, it shows that it should be 0.01% by mass to 5% by mass.

Comparative Example 4 shows that when the total amount of the first and second polyglyceryl fatty acid esters in the composition is more than 5% by mass relative to the total mass of the composition, the composition can be made transparent or slightly translucent. indicates that it is not possible.

(Examples 6-7 and Comparative Example 5)
The following compositions shown in Table 3, according to Examples 6-7 and Comparative Example 5, were prepared by mixing the ingredients shown in Table 3. All numerical values for the amount of ingredients shown in Table 3 are based on "% by weight" of the raw material.

The composition according to Example 6 was a composition comprising micelles formed by PG-4 caprate and PG-2 oleate.

The compositions according to Example 7 and Comparative Example 5 were in the form of O/W emulsions.

[evaluation]
(turbidity)
The turbidity of the compositions according to Examples 6-7 was measured at room temperature by using a turbidity meter (2100Q portable, Hach Company).

The results are shown in Table 3 as "NTU". The lower the NTU value, the more transparent the composition.

The compositions according to Examples 6 and 7 were transparent or slightly translucent.

The NTU value of the composition according to Comparative Example 5 was not tested as the composition was opaque.

(Droplet diameter)
The size of the dispersed phase in the compositions according to Examples 6-7 was measured using a dynamic light scattering particle size analyzer ELSZ-2000 (Otsuka Electronics Co., Ltd.).

Table 3 shows the results.

The droplet size of the composition according to Example 6 refers to the average size of the oil-free micelles in the composition.

The droplet size of the composition according to Example 7 means the average size of the oil droplets in the composition, which can be considered as oil-containing micelles.

The droplet size of the dispersed phase in the composition according to Comparative Example 5 was not tested because the composition was opaque.

Examples 6-7 show (amount of oil)/(total amount of first polyglyceryl fatty acid ester with HLB value greater than 11.0 and second polyglyceryl fatty acid ester with HLB value less than 11.0) in the composition should be less than 0.3.

Comparative Example 5 is the mass of (amount of oil)/(total amount of the first polyglyceryl fatty acid ester having an HLB value of greater than 11.0 and the second polyglyceryl fatty acid ester having an HLB value of less than 11.0) in the composition. A ratio greater than or equal to 0.3 indicates that the composition cannot be made transparent or slightly translucent.

(Examples 8-9 and Comparative Examples 6-7)
The following compositions shown in Table 4, according to Examples 8-9 and Comparative Examples 6-7, were prepared by mixing the ingredients shown in Table 4. All numerical values for the amount of ingredients shown in Table 4 are based on "% by weight" of the raw material.

The compositions according to Examples 8-9 and Comparative Examples 6-7 were in the form of O/W emulsions.

[evaluation]
(turbidity)
The turbidity of the compositions according to Examples 8-9 was measured at room temperature by using a turbidity meter (2100Q portable, Hach Company).

The results are shown in Table 4 as "NTU". The lower the NTU value, the more transparent the composition.

The compositions according to Examples 8 and 9 were transparent or slightly translucent.

The NTU values of the compositions according to Comparative Examples 6-7 were not tested as the compositions were opaque.

(Droplet diameter)
The size of the dispersed phase in the compositions according to Examples 8-9 was measured using a dynamic light scattering particle size analyzer ELSZ-2000 (Otsuka Electronics Co., Ltd.).

Table 4 shows the results.

The droplet size of the dispersed phase in the compositions according to Comparative Examples 6-7 was not tested because the compositions were opaque.

Examples 8-9 show the weight ratio of (the amount of the second polyglyceryl fatty acid ester having an HLB value of less than 11.0)/(the amount of the first polyglyceryl fatty acid ester having an HLB value of greater than 11.0) in the composition. , indicating that it should be greater than 0.01 and less than 0.2.

Comparative Examples 6 and 7 show that the mass ratio of (the amount of the second polyglyceryl fatty acid ester having an HLB value of less than 11.0)/(the amount of the first polyglyceryl fatty acid ester having an HLB value of greater than 11.0) in the composition was If it is less than 0.01 or greater than 0.2, it indicates that the composition cannot be made transparent or slightly translucent.

(Examples 10-11 and Comparative Examples 8-9)
The following compositions shown in Table 5, according to Examples 10-11 and Comparative Examples 8-9, were prepared by mixing the ingredients shown in Table 5. All numerical values for the amount of ingredients shown in Table 5 are based on "% by weight" of the raw material.

The compositions according to Examples 10-11 and Comparative Examples 8-9 were in the form of O/W emulsions.

[evaluation]
(turbidity)
The turbidity of the compositions according to Examples 10-11 was measured at room temperature by using a turbidimeter (2100Q portable, Hach Company).

The results are shown in Table 5 as "NTU". The lower the NTU value, the more transparent the composition.

The compositions according to Examples 10 and 11 were transparent or slightly translucent.

The NTU values of the compositions according to Comparative Examples 8-9 were not tested because the compositions were opaque.

(Droplet diameter)
The size of the dispersed phase in the compositions according to Examples 10-11 was measured using a dynamic light scattering particle size analyzer ELSZ-2000 (Otsuka Electronics Co., Ltd.).

Table 5 shows the results.

The droplet size of the dispersed phase in the compositions according to Comparative Examples 8-9 was not tested because the compositions were opaque.

Examples 10-11 show (amount of polyol having 5 or more carbon atoms)/(a first polyglyceryl fatty acid ester having an HLB value of greater than 11.0 and a second polyglyceryl fatty acid ester having an HLB value of less than 11.0 in the composition). and polyglyceryl fatty acid ester) should be more than 0.1 and less than 5.

Comparative Examples 8-9 show (amount of polyol having 5 or more carbon atoms)/(a first polyglyceryl fatty acid ester having an HLB value of greater than 11.0 and a second polyglyceryl fatty acid ester having an HLB value of less than 11.0 in the composition). and the total amount of polyglyceryl fatty acid ester) is 0.1 or less or 5 or more, it indicates that the composition cannot be made transparent or slightly translucent.

(Examples 12-15)
The following compositions shown in Table 6 according to Examples 12-15 were prepared by mixing the ingredients shown in Table 6. All numerical values for the amounts of ingredients shown in Table 6 are based on "% by weight" of the raw material.

The compositions according to Examples 12-15 were in the form of O/W emulsions.

[evaluation]
(turbidity)
The turbidity of the compositions according to Examples 12-15 was measured at room temperature by using a turbidity meter (2100Q portable, Hach Company).

The results are shown in Table 6 as "NTU". The lower the NTU value, the more transparent the composition.

The compositions according to Examples 12-14 were transparent or slightly translucent.

(Droplet diameter)
The size of the dispersed phase in the compositions according to Examples 12-15 was measured using a dynamic light scattering particle size analyzer ELSZ-2000 (Otsuka Electronics Co., Ltd.).

Table 6 shows the results.

Examples 12-15 demonstrate that compositions according to the present invention can contain varying amounts of hyaluronic acid or salts thereof, regardless of the molecular weight of hyaluronic acid, to render the composition transparent or slightly translucent. there is

(Examples 16-18 and Comparative Example 10)
The following compositions shown in Table 7, according to Examples 16-18 and Comparative Example 10, were prepared by mixing the ingredients shown in Table 7. All numerical values for the amount of ingredients shown in Table 7 are based on "% by weight" of the raw material.

The compositions according to Examples 16-18 and Comparative Example 10 were in the form of O/W emulsions.

[evaluation]
(turbidity)
The turbidity of the compositions according to Examples 16-18 was measured at room temperature by using a turbidimeter (2100Q portable, Hach Company).

The results are shown in Table 7 as "NTU". The lower the NTU value, the more transparent the composition.

The compositions according to Examples 16-18 were transparent or slightly translucent.

The NTU value of the composition according to Comparative Example 10 was not tested as the composition was opaque.

(Droplet diameter)
The size of the dispersed phase in the compositions according to Examples 16-18 was measured using a dynamic light scattering particle size analyzer ELSZ-2000 (Otsuka Electronics Co., Ltd.).

Table 7 shows the results.

The droplet size of the dispersed phase in the composition according to Comparative Example 10 was not tested because the composition was opaque.

Example 16 shows that the type of polyglyceryl fatty acid ester is not limited.

Example 17 shows that the type of polyol with 5 or more carbon atoms is not limited.

Example 18 shows that the type of oil is not limited.

Comparative Example 10 shows that when polyols with less than 5 carbon atoms are used in the composition, the composition cannot be made transparent or slightly translucent.

(Examples 19-25)
The following compositions shown in Table 8, according to Examples 19-25, were prepared by mixing the ingredients shown in Table 8. All numerical values for the amount of ingredients shown in Table 8 are based on "% by weight" of the raw material.

The compositions according to Examples 19-25 were in the form of O/W emulsions.

[evaluation]
(turbidity)
The turbidity of the compositions according to Examples 19-25 was measured at room temperature by using a turbidimeter (2100Q portable, Hach Company).

The results are shown in Table 8 as "NTU". The lower the NTU value, the more transparent the composition.

The compositions according to Examples 19-25 were transparent or slightly translucent.

(Droplet diameter)
The size of the dispersed phase in the compositions according to Examples 19-25 was measured using a dynamic light scattering particle size analyzer ELSZ-2000 (Otsuka Electronics Co., Ltd.).

Table 8 shows the results.

Examples 19-25 demonstrate that the type of hyaluronic acid or its salts is not limited.

Claims (15)

(a) at least one optional oil;
(b) at least one first polyglyceryl fatty acid ester having an HLB value greater than 11.0, preferably greater than 12.0, more preferably greater than 13.0;
(c) at least one second polyglyceryl fatty acid ester having an HLB value of less than 11.0, preferably less than 10.0, more preferably less than 9.0;
(d) at least one hyaluronic acid component selected from the group consisting of hyaluronic acid, hyaluronic acid salts, hyaluronic acid derivatives, hyaluronic acid derivative salts, and mixtures thereof;
(e) at least one polyol having 5 or more carbon atoms, and
(f) a composition comprising water,
The total amount of (b) the first polyglyceryl fatty acid ester and (c) the second polyglyceryl fatty acid ester is 0.01% by mass to 5% by mass relative to the total amount of the composition,
The mass ratio of ((a) amount of oil)/(total amount of (b) first polyglyceryl fatty acid ester and (c) second polyglyceryl fatty acid ester) is less than 0.3;
The mass ratio of ((c) the amount of the second polyglyceryl fatty acid ester)/((b) the amount of the first polyglyceryl fatty acid ester) is more than 0.01 and less than 0.2,
The mass ratio of ((e) amount of polyol having 5 or more carbon atoms)/(total amount of (b) first polyglyceryl fatty acid ester and (c) second polyglyceryl fatty acid ester) is more than 0.1 to 5 is less than
The composition comprises a continuous phase and a dispersed phase, the dispersed phase having a size of 300 nm or less, preferably 200 nm or less, more preferably 100 nm or less.
Composition. 2. A composition according to claim 1, wherein (a) the oil is selected from polar oils. 3. The claim 1 or 2, wherein the amount of (a) oil in the composition is less than 0.7% by weight, preferably less than 0.6% by weight, more preferably less than 0.5% by weight relative to the total weight of the composition. composition. 4. Any one of claims 1 to 3, wherein (b) the first polyglyceryl fatty acid ester comprises 2 to 4 glycerol units, preferably 3 or 4 glycerol units, more preferably 4 glycerol units. The composition according to . (b) the fatty acid portion of the first polyglyceryl fatty acid ester contains 12 carbon atoms or less, preferably 11 carbon atoms or less, more preferably 10 carbon atoms or less; A composition according to claim 1. The amount of (b) the first polyglyceryl fatty acid ester in the composition is 0.01% by mass to 5% by mass, preferably 0.1% by mass to 4% by mass, more preferably 1% by mass, relative to the total mass of the composition. A composition according to any one of claims 1 to 5, which is ∼3% by weight. 7. Any one of claims 1 to 6, wherein (c) the second polyglyceryl fatty acid ester comprises 2 to 4 glycerol units, preferably 2 or 3 glycerol units, more preferably 2 glycerol units. The composition according to . (c) The fatty acid portion of the second polyglyceryl fatty acid ester contains 14 or more carbon atoms, preferably 16 or more carbon atoms, more preferably 18 or more carbon atoms. A composition according to claim 1. The amount of (c) the second polyglyceryl fatty acid ester in the composition is 0.001% by mass to 0.5% by mass, preferably 0.01% by mass to 0.4% by mass, more preferably 0.1% by mass, relative to the total mass of the composition. A composition according to any one of claims 1 to 8, which is ∼0.3% by weight. (d) the hyaluronic acid component is selected from hyaluronic acid, hydrolyzed hyaluronic acid, acetylated hyaluronic acid, cationic hyaluronic acid, salts thereof, and mixtures thereof; The described composition. The amount of (d) hyaluronic acid component in the composition is 0.001% by mass to 5% by mass, preferably 0.01% by mass to 4% by mass, more preferably 0.1% by mass to 3% by mass, relative to the total mass of the composition. %. (e) the polyol with 5 or more carbon atoms is selected from diols with ₅ or more carbon atoms, preferably C5 _- C10 diols, more preferably pentylene glycol, hexylene glycol, and mixtures thereof; 12. The composition of any one of claims 1-11, wherein The amount of (e) polyol having 5 or more carbon atoms in the composition is from 0.01% to 7%, preferably from 0.1% to 6%, more preferably from 0.1% to 6% by weight, relative to the total weight of the composition. A composition according to any one of claims 1 to 12, which is in the range of 1% to 5% by weight. 14. A composition according to any one of claims 1 to 13, comprising (a) oil and in the form of an O/W emulsion. 15. A cosmetic method for treating keratinous material, comprising applying a composition according to any one of claims 1 to 14 to the keratinous material.