JP2022151078A - PORT MEMBER AND CONTAINER FOR LIQUID CONTAINER AND LIQUID-FILLED CONTAINER FOR BIOLOGICAL ADMINISTRATION - Google Patents

Abstract

To provide a port member that is attached to a container for storing liquid and that can ensure sealing and opening property as well as ensuring insertion property of other member, and a liquid storage container and a liquid-filled container for living body administration.SOLUTION: A port member 30 includes a cylindrical base part 31, a cylindrical port body part 32 protruded in the distal direction from the base part 31, a closing part 33 extending in the distal direction from the port body part 32, and an annular concave part 35 provided between the port body part 32 and the closing part 33 and forming an annular thin wall part 34 for breaking. The port body part 32 has an annular inner peripheral surface corner part 36 formed on the inner peripheral surface. The annular concave part 35 has an annular inner edge corner part 37. The annular inner peripheral corner part 36 is provided at a position close to the annular inner edge corner part 37 and closer to the base part 31 than the annular inner edge corner part 37.SELECTED DRAWING: Figure 4

Description

TECHNICAL FIELD The present invention relates to a port member attached to a container for containing a liquid, a container for containing a liquid, and a container filled with a liquid for biological administration.

2. Description of the Related Art Conventionally, there has been known a container in which a bag-shaped container main body contains a liquid substance such as a fluid food or a liquid medicine, and a port member for discharging the liquid substance is attached to the container main body. As such a port member, a closing portion integrally formed with the port main body portion is provided, and the container is sealed by the closing portion, and the container is opened by separating (breaking) the closing portion to open the liquid material. is known to be discharged to the outside.

For example, Patent Document 1 (Japanese Patent Application Laid-Open No. 2013-060213) discloses a one-piece spout (port member) that is provided in a bag-like container and used as a content pouring tool. A break-off member is connected to the upper end of the container through a breakable thin-walled portion, and by removing the broken-off portion by breaking the thin-walled portion, it is possible to pour out the contents of the container.

In addition, Patent Document 2 (Japanese Patent Application Laid-Open No. 2014-091572) discloses a spout (port member) in which a flow path is closed by a break-off portion integrally formed via a cylindrical portion and a weakened portion, and a spout body Disclosed is a spout provided with a cover that is separately formed so as to cover from the tip side of the spout and cover the break-off portion, which damages the weakened portion during assembly, transportation, and storage, resulting in poor sealing. It is disclosed to prevent damage.

JP 2013-060213 A JP 2014-091572 A

In the port member as described above, it is necessary to ensure the strength (thickness) of the thin portion formed as a breakable portion in order to ensure the sealing performance of the port member (and thus the container to which the port member is attached). On the other hand, if the strength (thickness) is too large, there is a problem that the opening property of the container (the ease with which the closing portion can be separated) is impaired, or the port main body portion deforms as the closing portion is separated. In addition, it is necessary to avoid contamination of the container with burrs generated at the broken portion.
Furthermore, for example, in recent years, when adopting such a structure in a female connector specified in ISO 080369-3, which has been decided to be introduced in Japan for the purpose of preventing incorrect connection in gastrostomy and nasogastric tubes in the field of enteral nutrition. In addition, it is necessary to ensure the insertability of other members (connector members) after removing the blocking portion (not to hinder the insertion of other members).
SUMMARY OF THE INVENTION Accordingly, an object of the present invention is to provide a port member to be attached to a container for storing a liquid, which ensures sealing and unsealing properties, as well as ensuring insertability of other members, and a container for storing a liquid. and to provide a container filled with a liquid for biological administration.

What achieves the above objectives is the following.
(1) A port member attached to a container for storing a liquid,
The port member includes a cylindrical base portion, a cylindrical port main portion projecting from the base portion in the distal direction, a closing portion extending from the port main portion in the distal direction, and the port main portion and the closing portion. an annular recess provided between and forming an annular thinned portion for breaking,
The port main body has an annular inner peripheral surface corner formed on the inner peripheral surface,
The annular recess comprises an annular inner edge corner,
The annular inner peripheral surface corner portion is provided at a position closer to the annular inner edge corner portion and closer to the base portion than the annular inner edge corner portion.

(2) The port member according to (1) above, wherein the port main body includes an annular internal stepped portion with a small inner diameter, and the annular inner circumferential surface corner portion is formed by the internal stepped portion. .
(3) The annular concave portion has an annular bottom portion perpendicular to the central axis of the port body portion or slightly inclined in the distal direction, and an annular inclined portion extending in the distal direction and outward from the inner edge of the annular bottom portion. The port member according to the above (1) or (2), further comprising a surface portion, wherein the annular inner edge corner portion is formed by the annular bottom surface portion and the inner edge portion of the annular inclined surface portion.
(4) The port member according to any one of (1) to (3) above, wherein the annular inner edge corner portion is located outside the inner peripheral surface of the port body portion.
(5) In the above (1), the port member has a minimum wall thickness between the annular inner edge corner portion and the annular inner peripheral surface corner portion at the connecting portion between the port body portion and the closing portion. ) to (4).
(6) The port member according to (5) above, wherein the wall thickness between the annular inner edge corner portion and the annular inner peripheral corner portion is 0.10 mm to 0.35 mm.
(7) The port member includes a breaking operation member fixed to the closing portion, the breaking operation member includes a body portion and an operation portion projecting outward from the body portion, and the port member The port member according to any one of (1) to (6) above, wherein the closing portion can be separated from the port body portion at the annular thin portion by rotating the breaking operation member.
(8) The port member according to any one of (1) to (7) above, wherein the liquid is a liquid for biological administration.

Moreover, what achieves the above purpose is as follows.
(9) A container for storing liquid, comprising a container body having an outlet, and the port member according to any one of (1) to (8) above attached to the outlet.

Moreover, what achieves the above purpose is as follows.
(10) A liquid-filled container for biological administration, wherein the liquid for biological administration is contained in the liquid-containing container according to (9) above.

The port member of the present invention includes a cylindrical base portion, a cylindrical port main portion projecting from the base portion in the distal direction, a closing portion extending from the port main portion in the distal direction, and a portion between the port main portion and the closing portion. an annular recess provided to form an annular thinned portion for breaking, the port body portion including an annular inner peripheral corner portion formed on the inner peripheral surface, the annular recess including an annular inner edge corner portion, The annular inner peripheral surface corner portion is provided at a position close to the annular inner edge corner portion and closer to the base portion side than the annular inner edge corner portion. As a result, it is possible to ensure the sealability and unsealability of the port member (and thus the container to which the port member is attached), and to ensure the insertability of other members.

A container for storing a liquid according to the present invention includes a container body having a discharge port, and the predetermined port member attached to the discharge port. As a result, it is possible to ensure the sealability and unsealability of the port member (and thus the container to which the port member is attached), and to ensure the insertability of other members.

In the liquid-filled container for bioadministration of the present invention, the liquid for bioadministration is stored in the predetermined liquid-storage container. As a result, it is possible to ensure the sealability and unsealability of the port member (and thus the container to which the port member is attached), and to ensure the insertability of other members.

FIG. 1 is a front view showing an embodiment of a liquid-filled container for biological administration provided with a port member of the present invention. FIG. 2 is an enlarged explanatory view of part A in FIG. 3 is a plan view of a portion corresponding to FIG. 2. FIG. FIG. 4 is an enlarged cross-sectional partial explanatory view showing the BB cross section of FIG. FIG. 5 is an enlarged explanatory view of the C portion in FIG. FIG. 6 is a front view showing an embodiment of a liquid-filled container for biological administration comprising a port member of the present invention comprising a breaking operation member. 7 is an enlarged plan view of a portion corresponding to the E section of FIG. 6. FIG. FIG. 8 is an enlarged cross-sectional partial explanatory view showing the FF cross section of FIG. FIG. 9 is an enlarged cross-sectional partial explanatory view showing a state in which the closing portion is separated in the port member of the present invention. FIG. 10 is an enlarged cross-sectional partial explanatory view showing an embodiment of a connector member connectable to the port member of the present invention. FIG. 11 is an enlarged cross-sectional partial explanatory view showing a connection mode between the port member and the connector member of the present invention. 12A and 12B are explanatory diagrams showing aspects of test examples relating to the port member of the present invention. FIG. 13 is a cross-sectional photograph showing an aspect of a test example relating to the port member of the present invention. FIG. 14 is a cross-sectional photograph showing an aspect of a test example relating to the port member of the present invention. FIG. 15 is a cross-sectional photograph showing an aspect of a test example relating to the port member of the present invention. FIG. 16 is a cross-sectional photograph showing an aspect of a test example relating to the port member of the present invention. FIG. 17 is an enlarged cross-sectional partial explanatory view corresponding to FIG. 5, showing another embodiment of the port member of the present invention. FIG. 18 is an enlarged cross-sectional partial explanatory view corresponding to FIG. 5, showing another embodiment of the port member of the present invention. FIG. 19 is an enlarged cross-sectional partial explanatory view corresponding to FIG. 5, showing another embodiment of the port member of the present invention. FIG. 20 is an enlarged cross-sectional partial explanatory view corresponding to FIG. 5, showing another embodiment of the port member of the present invention. 21 is an enlarged cross-sectional partial explanatory view corresponding to FIG. 4, showing another embodiment of the port member of the present invention; FIG. 22 is an enlarged cross-sectional partial explanatory view corresponding to FIG. 4, showing another embodiment of the port member of the present invention; FIG.

The port member of the present invention, a container for storing a liquid, and a container filled with a liquid for biological administration will be described with reference to the drawings. 1 to 5, for convenience of explanation, the port member is shown without the breaking operation member.

As shown in FIGS. 1 to 8, the port member 30 of the present invention is a port member 30 attached to a container (container main body 11 of liquid container 10) for containing a liquid (liquid for biological administration 20). be. The port member 30 includes a cylindrical base portion 31 , a cylindrical port body portion 32 projecting in the distal direction from the base portion 31 , a blocking portion 33 extending in the distal direction from the port body portion 32 , and the port body portion 32 . An annular recess 35 is provided between the closing portions 33 and forms an annular thinned portion 34 for breaking. Further, the port body portion 32 includes an annular inner peripheral corner 36 formed on the inner peripheral surface, the annular recess 35 includes an annular inner peripheral corner 37, and the annular inner peripheral corner 36 includes an annular inner peripheral corner. It is provided at a position close to the portion 37 and closer to the base portion 31 than the annular inner edge corner portion 37 .

As shown in FIGS. 1 to 8, the liquid material storage container 10 of the present invention includes a container body 11 having a discharge port 12, and the port member 30 is attached to the discharge port 12. FIG. Further, in the container 1 filled with a liquid for biological administration of the present invention, the liquid for biological administration 20 as a liquid is contained in the container 10 for containing a liquid. Examples of the liquid material for biological administration 20 include fluid foods and other fluid foods used in the field of enteral nutrition, and various drug solutions and infusion solutions used for drip infusion and the like.

The container main body 11 is in the shape of a flexible bag, and contains the liquid substance for biological administration 20 therein. At the top of the container body 11, a discharge port 12 is provided for communicating the inside and the outside of the container body 11 (for discharging the liquid substance for biological administration 20 stored inside the container body 11 to the outside). there is A port member 30 is attached to the outlet 12 of the container body 11 .

As shown in FIGS. 2 and 3, the port member 30 has a tubular base portion 31 . A rhombus-shaped plate-like portion 38 and a boat-shaped mounting portion 39 (indicated by broken lines in FIG. 2) are provided on the base portion 31 further on the base end side (container body 11 side). The port member 30 is attached to the outlet 12 of the container body 11 at the attachment portion 39 . More specifically, the mounting portion 39 is housed inside the discharge port 12 , and the inner surface portion of the discharge port 12 is liquid-tightly fixed to the outer surface portion of the mounting portion 39 (adhesion, heat welding, or the like).

In the port member 30 of this embodiment, the plate-like portion 38 has a plate-like shape extending outward from the proximal end of the base portion 31 . The lower surface of the plate-like portion 38 contacts the upper surface of the discharge port 12 of the container body 11 to seal the discharge port 12 . The plate-like portion 38 preferably has a substantially rhombic shape as in this embodiment, but may have a circular, elliptical, or polygonal shape.

The mounting portion 39 has a tubular shape extending a predetermined length downward from the lower surface of the plate-like portion 38 . The outer edge shape of the upper end of the mounting portion 39 is smaller than the outer edge shape of the lower surface of the plate-like portion 38 , and the plate-like portion 38 has an annular projecting portion projecting from the mounting portion 39 on the lower surface. In addition, in the port member 30 of this embodiment, the attachment portion 39 has a boat shape, more specifically, a rhombic cross section perpendicular to the axial direction. The attachment portion 39 may have a cylindrical shape, an oval cylindrical shape, or a polygonal cylindrical shape. Further, in the port member 30 of this embodiment, the mounting portion 39 has a convex portion and a concave portion on the outer surface.

In this embodiment, the port member 30 includes a cylindrical port body portion 32 projecting from the base portion 31 toward the distal direction, a closing portion 33 extending from the port body portion 32 toward the distal direction, and the port body portion 32 and the closing portion. An annular recess 35 provided between the portions 33 and forming an annular thinned portion 34 for breaking.

As shown in FIG. 4, the port main body 32 has a hollow cylindrical shape, and in the open state, the inside of the liquid container 10 can communicate with the outside (the liquid for biological administration 20 can be discharged to the outside). In addition, a distal end portion 55 (connector member distal end portion 55) of a first cylindrical portion 51 of the connector member 50, which will be described later, can be inserted (entered) into the interior thereof. Further, a screwing rib 40 is formed on the outer peripheral surface of the port body portion 32 . The screwing rib 40 is a helical rib protruding outward, and can be screwed with a screwing groove 53 of the connector member 50 described later.

As shown in FIGS. 4 and 5, the port body portion 32 has an annular inner circumferential surface corner portion 36 formed on the inner circumferential surface. More specifically, the port body portion 32 has an annular internal stepped portion 41 with a small inner diameter, and the annular inner circumferential surface corner portion 36 is formed by the internal stepped portion 41 . In other words, with the internal stepped portion 41 interposed therebetween, the inner diameter: d of the closing portion 33 side is smaller than the inner diameter: D of the port body portion 32 . Here, the internal stepped portion 41 (internal stepped surface) extends in a direction perpendicular to the central axis of the port body portion 32 (substantially horizontally). In this embodiment, the annular inner peripheral surface corner portion 36 is formed by a connecting portion between an annular top portion (first annular top portion) of the inner peripheral surface and an annular flat portion extending from the annular top portion toward the center. The annular inner peripheral surface corner portion 36 is preferably a sharp corner portion, but may be slightly rounded.

As shown in FIG. 4, the port main body portion 32 of the port member 30 has substantially the same inner diameter (at the portion below the internal stepped portion 41) except for the portion where the internal stepped portion 41 is formed. In other words, the inner surface of the portion of the port main body 32 excluding the internal stepped portion 41 is a straight surface (cylindrical surface extending with substantially the same diameter) substantially parallel along the axial direction. Here, "the inner diameters are substantially the same (straight surfaces that are substantially parallel along the axial direction)" means that the port member 30 is allowed to have an inclination to the extent of a draft angle that is set when the port member 30 is molded. As a result, the port member 30 having the closing portion 33, which will be described in detail later, can be more easily molded.

Port member 30 includes a blocking portion 33 extending distally from port body portion 32 . As shown in FIG. 4 , the blocking portion 33 is connected to the distal end of the port body portion 32 and has a cylindrical shape having a closed distal end with a distal end side portion blocked. In the state where the closing portion 33 exists, the port body portion 32 is closed (the liquid container 10 is sealed). A breaking operation rib 42 projecting outward is formed on the outer peripheral surface of the closing portion 33 . Here, the closing portion 33 is formed with a pair of breaking operation ribs 42, 42 protruding in mutually opposite directions.

An annular recess 35 forming an annular thin wall portion 34 for breaking is provided between the port body portion 32 and the closing portion 33 . The annular recess 35 has an annular inner edge corner 37 . In this embodiment, as shown in FIG. 5, the annular recessed portion 35 includes an annular bottom portion 43 perpendicular to the central axis of the port body portion 32 (or slightly inclined toward the distal direction) and an inner edge of the annular bottom portion 43. An annular inner edge corner portion 37 is formed by the annular bottom surface portion 43 and the inner edge portion of the annular inclined surface portion 44 . Note that the annular inclined surface portion 44 may be an annular curved surface extending outward from the inner edge of the annular bottom surface portion 43 in the distal direction.

It is preferable that the annular bottom surface portion 43 is inclined at 0° (horizontal) to ±10° toward the distal direction or the proximal direction with respect to a plane (horizontal plane) perpendicular to the central axis of the port body portion 32 . . The angle θ between the annular bottom surface portion 43 and the annular inclined surface portion 44 is preferably 40° to 50°, more preferably 45°.

As shown in FIG. 5, the annular inner edge corner portion 37 is positioned outward from the inner peripheral surface of the port body portion 32 (the inner peripheral surface of the port body portion 32 including the internal stepped portion 41). Here, the annular inner edge corner portion 37 is positioned radially outwardly by an amount indicated by X from the inner peripheral surface of the port body portion 32 . Note that the horizontal distance X between the annular inner edge corner portion 37 and the inner peripheral surface of the port body portion 32 shown here is preferably in the range of 0.17 mm to 0.25 mm, and more preferably, 0.19 mm to 0.21 mm.

As shown in FIG. 5, in the port member 30, the annular inner edge corner portion 37 and the annular inner peripheral surface corner portion 36 are formed at the connection portion (annular thin wall portion 34) between the port body portion 32 and the closing portion 33. The thickness between them (the distance between the annular inner edge corner portion 37 and the annular inner peripheral surface corner portion 36): t is minimized. The thickness t is preferably 0.10 mm to 0.35 mm, more preferably 0.15 mm to 0.30 mm, and particularly preferably 0.18 mm to 0.29 mm. If the thickness: t is within the above range, there is no risk of impairing the unsealability of the liquid container 10 (the ease with which the closing portion 33 can be separated), and there is no accidental breakage.

In the port member 30 , the annular inner peripheral surface corner portion 36 is provided at a position close to the annular inner edge corner portion 37 and closer to the base portion 31 than the annular inner edge corner portion 37 . Here, as shown in FIG. 5, the annular inner peripheral surface corner portion 36 is located on the base portion 31 side (lower in FIG. 5) than the annular inner edge corner portion 37 by the amount indicated by Y. The vertical distance Y between the annular inner edge corner portion 37 and the annular inner peripheral surface corner portion 36 shown here is preferably 0.0 mm to 0.2 mm. If the distance Y is greater than 0.2 mm, burrs generated when the closing portion 33 is separated (broken) from the port body portion 32 impair the insertability of another member (connector member 50), as will be described in detail later. There is a risk of exacerbating the problem (obstructing insertion of other members).

Materials for forming the port member 30 include hard synthetic resins, for example, resin materials such as polyolefins such as polypropylene and polyethylene, polycarbonate, polyester (PET), polystyrene, polyamide, rigid polyvinyl chloride, and ABS resin. . A preferred material for forming the port member 30 is high density polyethylene (HDPE). The port member 30 can be integrally molded, for example, by injection molding. Also, the port member 30 preferably conforms to ISO80369-3.

As shown in FIGS. 6 to 8 , the port member 30 includes a breaking operation member (cap) 60 fixed to the closing portion 33 . The breaking operation member 60 includes a body portion 61 and an operation portion 62 projecting outward from the body portion 61 . The port member 30 can separate the closing portion 33 from the port body portion 32 at the annular thin portion 34 by rotating the breaking operation member 60 .

More specifically, as shown in FIG. 8, the body portion 61 of the breaking operation member 60 has a cylindrical shape, and the upper portion of the port member 30 [the closing portion 33, the annular concave portion 35 (the annular thin portion 34 ), the port main body 32, and part of the base portion 31]. Cap-side ribs 63, 63 that engage with the breaking operation ribs 42, 42 formed on the closing portion 33 are formed on the inner peripheral surface of the body portion 61 so as to protrude inward. Each of the cap-side ribs 63 is composed of two ribs (only one of each is shown in FIG. 8), and engages so as to sandwich the breaking operation rib 42 in the circumferential direction. The breaking operation member 60 is fixed to the distal end portion of the closing portion 33 by heat welding or the like with the cap-side ribs 63, 63 engaged with the breaking operation ribs 42, 42 (welding portion 64). In this embodiment, the body portion 61 of the breaking operation member 60 covers the annular thin wall portion 34 and the annular concave portion 35 of the port member 30 described above. Therefore, the annular thin portion 34 is prevented from being damaged when an impact is applied to the breaking operation member 60 .

The breaking operation member 60 includes an operation portion 62 projecting outward from a body portion 61 . The breaking operation member 60 includes a pair of operation portions 62, 62 projecting from the main body portion 61 in opposite directions. The port member 30 can separate the closing portion 33 from the port body portion 32 at the annular thin portion 34 by rotating the breaking operation member 60 . By rotating the breaking operation member 60 using the operation portion 62 , a larger force (moment) can be applied to the thin annular portion 34 , and the closing portion 33 can be more easily removed from the port body portion 32 . It can be separated (twisted off).

As the material for forming the breaking operation member 60, the same hard synthetic resin as the material for forming the port member 30, for example, polyolefins such as polypropylene and polyethylene, polycarbonate, polyester (PET), polystyrene, polyamide, rigid polyvinyl chloride, and ABS. A resin material such as a resin can be used. High-density polyethylene (HDPE) is preferable as the material for forming the breaking operation member 60 .

In addition, the port member may not be provided with the breaking operation member. In that case, the closure can be separated (twisted) from the port body by direct rotational manipulation. At this time, the closing portion can also be rotated using a pair of breaking operation ribs formed on the closing portion. Moreover, the blocking part can be separated (break off) by applying a force in the lateral direction (in a direction substantially perpendicular to the axial direction) to the blocking part. It should be noted that it is preferable to twist off the blocking portion rather than breaking it off, and by providing the breaking operation member, it is possible to prevent the blocking portion from being unintentionally damaged or broken off. In addition, by providing the breaking operation member, the closing portion can be easily and properly separated from the port main body (twisted off) compared to the case where the breaking operation member is not provided (when the closing portion is directly operated). )be able to.

As shown in FIG. 9, in the port member 30, the closing portion 33 is separated from the port body portion 32, thereby opening the port body portion 32 (opening the liquid container 10). As a result, the liquid for biological administration 20 stored in the container 10 (container main body 11) can be discharged to the outside through the port member 30, and the port member 30 can be connected to another member (for example, to be described later). The connector member 50) can be connected. Then, as shown in FIG. 9, the port member 30 from which the closing portion 33 is separated is formed with an annular broken end 70 formed by breaking the annular thin portion 34 portion. In the port member 30 of this embodiment, the annular fracture end 70 has an inclined surface whose diameter increases upward.

As shown in FIG. 10, the connector member 50 connectable to the port member 30 includes a first cylindrical portion 51 connectable to the port member 30 and a second cylindrical portion ( lock adapter) 52 , and a threading protrusion 54 formed on the inner peripheral surface of the second tubular portion 52 and forming a threading groove 53 . In particular, the connector member 50 shown in FIG. 10 includes a first tubular portion 51 having an opening at the front end, a second tubular portion 52 covering the first tubular portion 51, and a tube connection portion having an opening at the rear end. and a flange portion 58 provided between the first tubular portion 51 and the connector portion 57 for tube connection. Then, as shown in FIG. 11 , a liquid injection tube 72 can be connected to the connector portion 57 .

The first cylindrical portion 51 has a tapered shape in which the outer diameter decreases toward the distal end. Specifically, the first cylindrical portion 51 has a nozzle shape with a 6% luer taper conforming to ISO594. The first tubular portion 51 can be connected not only to the port member of the present invention but also to other medical instruments (for example, a connector, a three-way stopcock).

The second tubular portion 52 is a tubular member and is attached to the first tubular portion 51 , and the tip of the first tubular portion 51 protrudes from the tip of the second tubular portion 52 . . The second tubular portion 52 has an annular rib provided at its proximal end portion and extending toward the center. This annular rib enters an annular recess provided on the outer peripheral surface of the first tubular portion 51 . Therefore, the second tubular portion 52 is rotatably attached to the first tubular portion 51 .

A threaded projection 54 forming a threaded groove 53 is formed on the inner peripheral surface of the second tubular portion 52 . The screwing protrusion 54 is a helical protrusion (so-called screw thread) that protrudes inward. A screwing groove portion 53 (a so-called thread root portion) is formed by the screwing projection portion 54 . The screwing groove portion 53 can be screwed with the screwing rib 40 of the port member 30 .

As a material for forming the connector member 50, the same hard synthetic resin as the port member 30, for example, polyolefin such as polypropylene and polyethylene, polycarbonate, polyester (PET), polystyrene, polyamide, polyethylene, rigid polyvinyl chloride, ABS resin, and the like can be used. A resin material can be mentioned. A preferred material for forming the connector member 50 is high density polyethylene (HDPE). The connector member 50 can be integrally formed by injection molding, for example. Also, the connector member 50 preferably conforms to ISO80369-3.

A mode of connecting the port member 30 and the connector member 50 after the blocking portion 33 is separated will be described. As shown in FIG. 11, by inserting the distal end portion 55 of the first cylindrical portion 51 of the connector member 50 into the port body portion 32 and relatively rotating the port member 30 and the connector member 50, the port member The screwing rib 40 of 30 and the screwing groove 53 of the connector member 50 are screwed together.

As the screwing between the port member 30 (screw rib 40) and the connector member 50 (screw groove 53) progresses, the connector member 50 moves toward the port member 30 (the distal end portion 55 advances in the port body portion 32). do. Here, since the distal end portion 55 of the first cylindrical portion 51 of the connector member 50 is tapered, the outer surface portion of the distal end portion 55 and the inner surface portion of the port body portion 32 of the port member 30 contact ( or pressure contact) to engage in a liquid-tight manner. As a result, the port member 30 (port body portion 32) and the connector member 50 (first cylindrical portion 51) are communicated with each other, and the liquid material (liquid material for biological administration) in the liquid material storage container 10 (container body 11) is communicated. 20) can be delivered to the patient via port member 30 and connector member 50.

In the port member 30 , the annular inner peripheral corner portion 36 formed on the inner peripheral surface of the port body portion 32 is closer to the annular inner edge corner portion 37 of the annular recessed portion 35 and is closer to the base than the annular inner edge corner portion 37 . It is provided at a position on the 31 side. As a result, it is possible to secure the sealability and unsealability of the port member 30 (and the liquid container 10 to which the port member 30 is attached), and to secure the insertability of other members.

That is, since the port member 30 has a predetermined shape of the annular thin-walled portion 34 (including the annular inner peripheral surface corner portion 36 and the annular inner edge corner portion 37) for breaking, there is a contradiction between the sealing performance and the opening performance of the port member 30. characteristics to be compatible.

In addition, for example, when the port member 30 is integrally molded by injection molding, to suppress deformation (sink marks, etc.) during molding [or to suppress deterioration in sealing performance due to such deformation (reduction in strength of the deformed portion)]. In addition, even if the holding pressure condition is set high and the packing density of the resin in the molded product (the entire port member 30) increases, the strength of the annular thin portion 34 is appropriately set to improve sealing and unsealing properties. can be secured. Furthermore, since no excessive force (moment) is required when unsealing (when separating the closing portion 33 from the port body portion 32), deformation of the port member 30 during unsealing can be avoided.

In addition, in the port member 30, the occurrence of burrs at the separation portion of the closing portion 33, that is, at the distal end portion of the port main body portion 32 after the closing portion 33 is separated, is suppressed, and burrs are generated toward the inside. is suppressed. As a result, burrs can be prevented from entering the liquid substance for biological administration 20 discharged from the liquid substance container 10 via the port member 30 , and other members (such as the connector member 50 ) can be connected to the port member 30 . The burr is unlikely to hinder the insertion of the other members, and the insertability of other members can be ensured.

Here, some test examples are shown to confirm the effect of the port member of the present invention. The port members of Test Examples 1 to 4 shown below have the same configuration as the port member 30 of the above embodiment, and have an annular inner edge corner portion 37 and an annular inner peripheral surface indicated by Y in the above embodiment. The vertical distance from the corner 36: Y [in other words, the formation position of the annular inner peripheral surface corner 36 (internal stepped portion 41) with respect to the annular inner edge corner 37] is, as shown in FIG. different. Also, the form and thickness of the minimum thickness portion are different as shown below.

In the port member of Test Example 1, the distance Y was 0.18 mm, and in the port member of Test Example 2, the distance Y was 0.2 mm. Further, in the port members of Test Examples 1 and 2, the wall thickness between the annular inner edge corner portion and the annular inner peripheral surface corner portion (the distance between the annular inner edge corner portion and the annular inner peripheral surface corner portion) is the minimum thickness portion (shortest distance portion), and the thickness of the minimum thickness portion (thickness between the annular inner edge corner and the annular inner peripheral corner: t) is the port of Test Example 1 In the member, it was 0.27 mm, and in the port member of Test Example 2, it was 0.29 mm.

The port members (30) of Test Examples 1 and 2 had good unsealability, and as shown in Figs. It was confirmed that the amount of burrs (71) generated at the tip of the port main body (32) after separation] was small, and that the burrs (71) were not generated inward.

In the port member of Test Example 3, the distance Y was 0.21 mm, and in the port member of Test Example 4, the distance Y was 0.22 mm. The position was set to some extent lower than the port members of Test Examples 1 and 2. In the port of Test Example 3 and the port member of Test Example 4, the wall thickness between the annular inner edge corner and the annular inner peripheral corner (the distance between the annular inner edge corner and the annular inner peripheral corner) ) is the minimum thickness portion (shortest distance portion), and the thickness of the minimum thickness portion (thickness between the annular inner edge corner and the annular inner peripheral surface corner: t) is the thickness of Test Example 3 The port member was 0.30 mm, and the port member of Test Example 4 was 0.31 mm. In addition, in Test Examples 3 and 4, the thickness of the side portion of the annular inner edge corner portion was 0.36 mm.

The port member (30) of Test Example 3 and Test Example 4 has a smaller force required for opening (separation of the closed portion) than the conventional port member in which the side portion of the annular inner edge corner portion has the smallest wall thickness. was small, but a larger force was required at the time of unsealing (at the time of separation of the closed portion) compared to the port members of Test Examples 1 and 2. Further, as shown in FIG. 15 (Test Example 3) and FIG. 16 (Test Example 4), burrs (the tip of the port main body (32) after separating the blocking portion) generated at the separation portion of the blocking portion ( 71) was generated in a larger amount than in the port members of Test Examples 1 and 2, and it was recognized that burrs (71) may be generated inwardly in part.

Figures 17-22 each show another embodiment of the port member of the present invention. These embodiments differ from the above-described embodiment (port member 30) in the form of the port main body portion (annular inner circumferential surface corner portion, internal stepped portion) and/or the annular concave portion. In these embodiments, unless otherwise specified, the same names and symbols (alphabet may be added to the end of the symbols) are used for configurations common to the above-described embodiments, and detailed descriptions thereof are omitted. .

In the port member 30a shown in FIG. 17, the annular bottom portion 43a forming the annular recess 35a (annular thin-walled portion 34a) is slightly inclined toward the distal end from the direction orthogonal to the central axis of the port body portion 32. there is

In the port member 30b shown in FIG. 18, the annular recess 35b (annular thin-walled portion 34b) is formed by an annular bottom portion 43 extending in a direction perpendicular to the central axis of the port body portion 32 and an inner edge of the annular bottom portion 43. and an annular curved surface portion 45 extending distally and outwardly. In the port member 30 b , an annular inner edge corner portion 37 b is formed by the inner edges of the annular bottom surface portion 43 and the annular curved surface portion 45 . The annular curved surface portion 45 may be curved downward.

In a port member 30c shown in FIG. 19, an annular recess 35c (annular thin-walled portion 34c) has an annular bottom portion 43 extending in a direction orthogonal to the central axis of the port body portion 32 and a tip from the inner edge of the annular bottom portion 43. and an annular top surface portion 47 extending outward from the upper edge of the annular vertical surface portion 46 (here, substantially parallel to the annular bottom surface portion 43). In the port member 30 c , an annular inner edge corner portion 37 c is formed by the inner edges of the annular bottom surface portion 43 and the annular vertical surface portion 46 .

In the port member 30d shown in FIG. 20, the internal stepped portion 41d (internal stepped surface) forming the annular inner peripheral corner portion 36d is inclined more toward the distal direction than the direction orthogonal to the central axis of the port body portion 32d. is doing.

In the port member 30e shown in FIG. 21, a solid portion 48 is formed in the upper portion (closed portion 33e portion) of the annular inner circumferential surface corner portion 36e of the port member 30e. In other words, in the port member 30e, the annular inner circumferential surface corner portion 36e is formed, but the internal stepped portion is not formed. Note that, like the port member 30f shown in FIG. 22, the upper portion (blocking portion 33f portion) of the annular inner circumferential surface corner portion 36f of the port member 30f is formed into a solid portion 48, and then the port member 30f (blocking portion 33f) is formed into a solid portion 48. A recess 49 may be provided in order to improve the moldability of the part).

1 Liquid substance-filled container for biological administration 10 Container for liquid substance storage 11 Container body 12 Discharge port 20 Liquid substance for biological administration 30 Port member 31 Base portion 32 Port body portion 33 Closing portion 34 Annular thin portion 35 Annular concave portion 36 Annular interior Peripheral surface corner portion 37 Annular inner edge corner portion 50 Connector member 60 Breaking operation member

Claims (10)

A port member attached to a container for storing a liquid,
The port member includes a cylindrical base portion, a cylindrical port main portion projecting from the base portion in the distal direction, a closing portion extending from the port main portion in the distal direction, and the port main portion and the closing portion. an annular recess provided between and forming an annular thinned portion for breaking,
The port main body has an annular inner peripheral surface corner formed on the inner peripheral surface,
The annular recess comprises an annular inner edge corner,
The port member, wherein the annular inner peripheral surface corner portion is provided at a position close to the annular inner edge corner portion and closer to the base portion than the annular inner edge corner portion. 2. The port member according to claim 1, wherein the port main body portion has an annular internal stepped portion with a reduced inner diameter, and the annular inner circumferential surface corner portion is formed by the internal stepped portion. The annular recess has an annular bottom surface perpendicular to the central axis of the port body or slightly inclined in the distal direction, and an annular inclined surface portion extending in the distal direction and outward from the inner edge of the annular bottom surface. 3. The port member according to claim 1, wherein said annular inner edge corner portion is formed by said annular bottom surface portion and said annular inclined surface portion's inner edge portion. The port member according to any one of claims 1 to 3, wherein the annular inner edge corner portion is positioned outward from the inner peripheral surface of the port body portion. 5. The port member according to any one of claims 1 to 4, wherein the wall thickness between the annular inner edge corner portion and the annular inner circumferential surface corner portion is the smallest at the connecting portion between the port body portion and the closing portion. A port member according to any one of the preceding claims. 6. The port member according to claim 5, wherein the wall thickness between the annular inner edge corner portion and the annular inner peripheral corner portion is 0.10 mm to 0.35 mm. The port member includes a breaking operation member fixed to the closing portion, the breaking operation member includes a main body portion and an operation portion projecting outward from the main body portion, and the port member includes: 7. The port member according to claim 1, wherein the closing portion can be separated from the port body portion at the annular thin portion by rotating the breaking operation member. 8. The port member according to any one of claims 1 to 7, wherein said liquid is a liquid for bioadministration. A container for storing a liquid, comprising a container body having a discharge port, and the port member according to any one of claims 1 to 8 attached to the discharge port. 10. A liquid-filled container for biological administration, wherein the liquid for biological administration is contained in the liquid-containing container according to claim 9.

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