JP2022103338A - Strength enhancer, and method of achieving strength enhancement with electronic vapor device - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a pre-vaporizing preparation for an e-vaping device (60).

SOLUTION: A pre-vaporizing preparation contains a vapor former containing at least one of propylene glycol and glycerol, and an additive containing at least one of carvacrol, thymol, monomenthyl succinate, and N-(2-hydroxyethyl)-2,3-dimethyl-2-isopropylbutanamide. Also provided is an e-vaping device (60) that has a cartomizer (70) that includes a reservoir (14) for holding the pre-vaporizing preparation, a mouth end piece, and a heater (19) configured to heat the pre-vaporizing preparation. The e-vaping device (60) further includes a power supply section that includes a smoking sensor (16) connected to the cartomizer (70) and configured to detect smoking taking place at the mouth end piece, and a power supply source configured to provide power to the heater (19).

SELECTED DRAWING: Figure 1

COPYRIGHT: (C)2022,JPO&INPIT

Description

The present invention generally relates to a pre-vaporization formulation for an e-vaping device. More specifically, the present invention relates to a strength enhancer of a pre-vaporized formulation.

An electronic vaporizing device (or e-vaping device) is used by an adult vapor inhaler to inhale the vapor, for example to vaporize a pre-vaporized product such as a liquid material into the vapor. The e-vaping device generally includes a heater that vaporizes the pre-vaporized formulation to produce vapor. The eBay device may include several eBaping elements, including a power source and a cartridge or eBaping tank (including a heater) and a reservoir for holding the pre-vaporized formulation.

Tobacco-based smoking articles have been found to create the desired sensory experience for adult smokers, including low to moderate harsh irritation of the throat and the warmth or intensity perceived in the chest of adult smokers. Generate a vapor that has been smoked.

Vapor thorniness, commonly perceived as a sensation experienced in the throat of an adult vapor aspirator, and vapor strength commonly perceived as a sensation experienced in the chest of an adult vapor aspirator in connection with an e-vaping device. It may vary based on the content and concentration of the pre-vaporization formulation used to form the vapor inhaled during vaporization by an adult vapor inhaler. In general, for similar amounts of nicotine in pre-vaporized formulations, e-vaping devices are more edgy than tobacco-based products, but less strong than tobacco-based products. As the amount of nicotine in the vapor phase of the vapor produced by the e-vaping device increases, so does the thorniness of the e-vaping device.

According to the first aspect, the present invention relates to an e-vaping device that is configured to achieve the desired balance of strength and thorniness and increases strength without increasing thorniness.

According to a second aspect, the present invention relates to an e-vaping device configured to provide an adult vapor aspirator with a sensory experience similar to the sensory experience enjoyed while smoking a cigarette-based cigarette.

According to a third aspect, the present invention is a sensation that includes a level of thorniness in the throat and a level of intensity or warmth perceived in the chest, similar to that experienced when smoking a tobacco-based product. With respect to an e-vaping device configured to provide an experience. In achieving the desired balance between strength and thorniness, the strength of the e-vaping product can be increased without increasing the thorniness.

According to a fourth aspect of the invention, the pre-vaporization formulation for the e-vaping device comprises a mixture of the vapor-forming body and one or more strength enhancers or additives.

The pre-vaporization preparation may contain water, one or more acids, or both water and one or more acids.
The pre-vaporization preparation may be a liquid preparation.

The pre-vaporization preparation may contain nicotine.

One or more strength enhancers or additives may include at least one of carvacrol, thymol, monomentyl succinate, N- (2-hydroxyethyl) -2,3-dimethyl-2-isopropylbutaneamide. good.

In at least one embodiment, the one or more strength enhancers or additives may comprise at least one of cinnamon aldehyde, menthone, eugenol, zingerone or vanillyl acetone, and gingerol.

One or more strength enhancers or additives include butane, allyl isothiocyanate, piperine, isoeugenol, carvacrol, thymol, menthol, monomenthol succinate, and N- (2-hydroxyethyl) -2,3-dimethyl-. It may contain at least one of 2-isopropylbutaneamide.

In at least one embodiment, the above compounds as well as others can be found in the extracts, such as horse radish oil, garlic extract, onion oil, black pepper, red pepper. , Ginger oil, thyme oil, cinnamon oil, turmeric, coloha, cardamon, rosemary extract, grapefruit oil, and andrography extract. The strength enhancer or additive may include at least one of these extracts.

One or more strength enhancers or additives include transient receptor potential cation channels, subfamily A, member 1 (TRPA1), transient receptor potential cation channels, subfamily V, member 1 (TPRV1), Alternatively, it may contain one or more compounds that activate receptors in the respiratory system of an adult vapor aspirator, such as the nicotinic acetylcholine receptor in an adult vapor aspirator, the antagonist becoming part of the vapor and vaporizing. Carried in the airways of adult vapor suckers.

In at least one embodiment, the strength enhancer or additive comprises, among other things, one or more of the compounds listed above in a composition range of about 0.0001 percent to about 1 percent, or up to about. It may be contained at a concentration of 2%. Optionally, when several strength enhancers are used in combination, the concentration of one or more strength enhancers or additives may be higher than about 2 percent. For example, the total concentration of strength enhancers may be up to about 5 percent.

In at least one embodiment, a compound that reduces thorniness, such as acid, is incorporated into the pre-vaporization formulation to achieve the desired balance of increasing strength and reducing thorniness within the e-vaping device. Can be included.

In at least one embodiment, one or more strength enhancers or additives may be used in a nicotine-free prevaporative formulation, the one or more strength enhancers or additives being nicotine-containing vaporization. It provides a level of strength similar to that experienced by an adult vapor aspirator when vaporizing a device or tobacco-based article. For example, such strength enhancers or additives may be included in smoking cessation inhalers.

In at least one embodiment, one or more strength enhancers or additives increase the strength of the e-vaping device without increasing the delivery of nicotine and without increasing the thorniness of the e-vaping article. do.

The pre-vaporization preparation may contain an amount of about 0.5 percent to about 2 percent or more, or about 0.5 percent to about 5 percent or more of nicotine. In at least one embodiment, the vapor formed by the vapor-forming body comprises a gas phase and a particle phase, and the concentration of nicotine in the vapor phase is about 1 percent or less.

According to a fifth aspect of the invention, the pre-vaporization formulation of the e-vaping device is about 0.5 weight percent to about 2 weight percent or more or about 0.5 percent to about 5 percent or more with the mixture of vapor forming bodies. Includes an amount of nicotine and one or more strength enhancers or additives. In at least one embodiment, the vapor formed by the vapor-forming body comprises a gas phase and a particle phase, and the concentration of nicotine in the vapor phase is about 1 percent or less. The pre-vaporization preparation may contain water, one or more acids, or both water and one or more acids. The pre-vaporization preparation may be a liquid preparation. One or more strength enhancers or additives may include one or more of any or preferred strength enhancers or additives according to a fourth aspect of the invention.

The pre-vaporized preparation according to the fourth or fifth aspect of the present invention may contain one or more acids. The pre-vaporization preparation may contain one or more acids at a concentration of about 0.1 percent to about 5 percent.

The boiling point of one or more acids may be at least about 100 ° C. and may be configured to volatilize when heated by a heater in the e-vaping device. The pre-vaporization formulation may be configured to form a vapor with a particle phase and a gas phase when heated by a heater in an e-vaping device, where the particle phase contains protonated nicotine and the gas phase is Aprotonated nicotine Contains aprotonated nicotine. In embodiments, the amount of vaporized nicotine is dominated by protonated nicotine and the amount of aprotonated nicotine is low.

In at least one embodiment, the pre-vaporization formulation is configured to form a vapor with a nicotine gas phase component during operation of the e-vaping device. The acid may be contained in an amount sufficient to reduce the nicotine vapor phase constituents by about 70 percent or more. In other embodiments, the addition of one or more acids reduces the gas phase nicotine content by an amount in the range of about 40 weight percent to about 70 weight percent or in the range of about 40 weight percent to about 90 weight percent. Can be done.

In at least one embodiment, the acid may be selected so that the evaporation efficiency is about 50 percent or more. The acid may be present in an amount sufficient to reduce the nicotine vapor phase constituents.

In at least one embodiment, the acids are pyruvate, formic acid, oxalic acid, glycolic acid, acetic acid, isovaleric acid, valeric acid, propionic acid, octanoic acid, lactic acid, sorbic acid, malic acid, tartaric acid, succinic acid, citric acid. , Savor acid, oleic acid, aconitic acid, butyric acid, silicic acid, decanoic acid, 3,7-dimethyl-6-octenoic acid, 1-glutamic acid, heptanic acid, hexanic acid, 3-hexaneic acid, trans-2-hexane Of acids, isobutyl acid, lauric acid, 2-methylbutyric acid, 2-methylvaleric acid, myristic acid, nonanoic acid, palmitic acid, 4-pentenoic acid, phenylacetic acid, 3-phenylpropionic acid, hydrochloric acid, phosphoric acid, and sulfuric acid. At least one of them may be included.

In at least one embodiment, the acid comprises pyruvic acid, lactic acid, benzoic acid, and acetic acid.

The vapor-forming body may contain propylene glycol and glycerol or glycerin. The vapor-forming body may contain substantially equal concentrations of propylene glycol and glycerol or glycerin.

The pre-vaporization preparation may contain water at a concentration of about 10 percent to about 20 percent.

According to a sixth aspect of the present invention, the e-vaping device includes a first section and a second section. The first section contains the pre-vaporized product (eg, liquid material, etc.), the heater, the core that communicates with the pre-vaporized product storage and the heater, the mouse end piece, and the distal end of the first section. Includes a pre-vaporized product storage that includes a connector. The second section includes a power supply and a connector at the proximal end of the second section configured to be matably connected to the connector in the first section.

According to a seventh aspect of the present invention, the e-vaping device includes a first section and a second section. The first section may be a cartomizer. The first section includes a pre-vaporized product reservoir containing the pre-vaporized product, a heater, and a mouse end piece. The heater is configured to heat the pre-vaporized formulation. The second section may be the power supply section. The second section contains a power source configured to power the heater. The pre-vaporization preparation may be the pre-vaporization preparation according to the fourth or fifth aspect of the present invention according to any of the embodiments described herein.

The first section may include a core that communicates with the pre-vaporized product reservoir and also communicates with the heater. The first section may be provided with a connector at the distal end of the first section.

The second section may include a smoke absorption sensor configured to detect the smoke absorption performed by the mouse end piece. The second section may be provided with a connector at the proximal end of the second section configured to be matably connected to the connector of the first section.

The above and other features and advantages of the exemplary embodiment will be further demonstrated by describing the exemplary embodiment in detail with reference to the accompanying drawings. The accompanying drawings are intended to depict exemplary embodiments and should not be construed as limiting the intended scope of the claims. The attached drawings should not be considered to be drawn in proportion to actual size unless explicitly noted.

FIG. 1 is a side view of an e-vaping device according to an exemplary embodiment. FIG. 2 is a cross-sectional view of an e-vaping device according to an exemplary embodiment. FIG. 3 is a cross-sectional view of another exemplary embodiment of the e-vaping device.

Several detailed exemplary embodiments are disclosed herein. However, the specific structural and functional details disclosed herein are merely exemplary for purposes of illustrating exemplary embodiments. However, exemplary embodiments can be embodied in a number of alternative embodiments and should not be construed as being limited to the embodiments described herein.

Thus, while exemplary embodiments allow for various modifications and alternatives, the embodiments are shown in the drawings as examples and are described in detail herein. However, of course, there is no intention to limit it to the exemplary embodiments disclosed, and conversely, the exemplary embodiments are any modifications that fall within the scope of the exemplary embodiments. Equals and alternatives are covered. Similar numbers mean similar elements throughout the description of the figure.

When an element or layer is referred to as "on top of", "connected to", "bonded to", or "covering" another element or layer, this is of the other element or layer. It should be understood that there may be elements or layers directly above, directly connected to, directly connected to, or directly covering, or intervening with it. In contrast, when an element is referred to as "directly above," "directly connected to," or "directly coupled to" another element or layer, the intervening element or layer. Does not exist. Similar numbers refer to similar elements throughout the specification.

Of course, the terms first, second, third, etc. may be used herein to describe various elements, components, areas, layers, or sections. These elements, components, areas, layers, or sections are not limited by these terms. These terms are used only to distinguish one element, component, area, layer, or section from another component, area, layer, or section. Accordingly, the first element, component, area, layer, or section discussed below does not deviate from the teachings of the exemplary embodiment and is a second element, component, area, layer, or section. It can also be called a section.

Spatial terms (eg, "down", "down", "bottom", "up", "top", and the like) are one element when illustrated in the figure. Alternatively, it may be used herein to facilitate the description of the relationship between a feature and other elements or features. It should be understood that spatially related terms are intended to include different directions of the device during use or operation, in addition to the directions illustrated in the figure. For example, if the device in the figure is flipped over, the element described as "down" or "down" for another element or feature is then oriented "up" for the other element or feature. It will be. Therefore, the term "downward" may include both upward and downward directions. The device may be otherwise oriented (rotated 90 degrees or in other directions) and the spatial relationship descriptive terms used herein are to be construed as appropriate.

The terms used herein are for purposes of illustration only, and are not intended to limit exemplary embodiments. The singular forms "one (a)", "one (an)", and "the" are intended to include the plural as used herein, but are apparent in context. This is not the case if it is indicated that this is not the case. The terms "includes," "includes," "comprises," and "comprising," as used herein, are the features, integers, processes, operations, described. It is further understood that it identifies the existence of an element, or component, but does not exclude the existence or addition of one or more other features, integers, processes, behaviors, elements, components, or groups thereof. Let's go.

Exemplary embodiments are described herein with reference to cross-sectional views that are schematics (and intermediate structures) of the ideal embodiments of the exemplary embodiments. Thus, changes from the shape of the figure obtained, for example as a result of manufacturing techniques or tolerances, are expected. Accordingly, exemplary embodiments should not be construed as limiting the shape of the regions illustrated herein and include, for example, manufacturing-induced shape deviations. Thus, the areas illustrated in the figures are de facto schematic and their shapes are not intended to illustrate the actual shape of the area of the device and are intended to limit the scope of the exemplary embodiments. do not have.

Unless defined otherwise, all terms used herein, including technical and scientific terms, are commonly understood by one of ordinary skill in the art to which the exemplary embodiments belong. Has the same meaning as. Terminology (including terms defined in commonly used dictionaries) should be construed to have a meaning consistent with the meaning of those terms in the context of the relevant technical discipline and is ideal. It will be further understood that, although not interpreted in an overly formal sense, this is not the case as expressly defined herein.

When the term "about" or "substantially" is used herein in combination with a numerical value, it is intended that the accompanying numerical value includes a tolerance of ± 10% before and after the specified numerical value. Further, when the percentages are referred to herein, they are intended to be based on weight, i.e., weight percentages. The expression "up to" includes the quantity from zero to the expressed upper limit and all values in between. When specifying a range, the range includes all values that fall within that range (eg, values that differ by 0.1%).

As used herein, the term "vapor-forming body" is any suitable that promotes the formation of vapors in use and is substantially resistant to thermal decomposition at the operating temperature of the e-vaping device. A well-known compound or mixture of compounds will be described. Suitable vapor-forming bodies consist of various compounds such as propylene glycol and polyhydric alcohols containing at least one of glycerol or glycerin. In at least one embodiment, the vapor-forming body is propylene glycol.

FIG. 1 is a side view of the e-vaping device 60 according to an exemplary embodiment. In FIG. 1, the e-vaping device 60 is combined at a threaded joint 74 or by other connection structures such as slide fits, snap fits, detents, clamps, or clasps, or one or more of the like. Includes a first section or cartomizer 70 and a second section 72 coupled to. In one embodiment, the first section or cartomizer 70 may be a replaceable cartridge and the second section 72 may be a reusable section. Alternatively, the first section or cartomizer 70 and the second section 72 may be integrally formed as one component.

FIG. 2 is a cross-sectional view of an exemplary embodiment of the e-vaping device. As illustrated in FIG. 2, the first section or cartomizer 70 comprises a mouth-side end insert 20, a capillary vapor generator including capillaries 18, a heater 19 for heating at least a portion of the capillaries 18, and storage. The unit 14 can be accommodated.

The second section 72 can accommodate the power source 12, the control circuit 11 configured to control the power source 12, and the smoke absorption sensor 16. The smoke absorption sensor is configured to detect when an adult vapor sucker sucks smoke with the e-vaping device 60, thereby causing the power supply 12 to operate via the control circuit 11 to activate the heater 19 and the storage unit 14. The pre-vaporized preparation contained therein is heated to form a vapor. The threaded portion 74 of the second section 72 can be connected to a battery charger to charge the battery or power supply 12 when not connected to the first section or the cartomizer 70.

As shown in FIG. 3, in another exemplary embodiment, the valve 40 can be a two-way valve and the reservoir 14 can be pressurized. For example, the storage unit 14 can be pressurized by using a pressurizing mechanism 405 configured to apply a constant pressure to the storage unit 14. Therefore, the discharge of the vapor formed by heating the pre-vaporized preparation contained in the storage unit 14 is promoted.

In an exemplary embodiment, the capillary tube 18 is formed from or contains a conductive material and thus acts as a unique heater 19 by passing an electric current through the tube. The capillary tube 18 may be a conductive material capable of resistance heating while maintaining the required structural perfection at the operating temperature experienced by the capillary tube 18 and which does not react with the pre-vaporization preparation. Suitable materials for forming the capillaries 18 are one or more of stainless steel, copper, copper alloys, porous ceramic materials covered with film resistant materials, nickel-chromium alloys, and combinations thereof. .. For example, the capillaries 18 are stainless steel capillaries 18 that function as heaters 19 via electrical leads 26 attached to them for the passage of direct current or alternating current along the length of the capillaries 18. Therefore, the stainless steel capillaries 18 are heated by resistance heating. Alternatively, the capillary tube 18 may be a non-metal tube such as a glass tube. In these embodiments, the heater 19 is made of or comprises a resistance-heatable conductive material, such as stainless steel, nichrome or platinum wire placed along a glass tube. When the heater disposed along the glass tube is heated, the pre-vaporization preparation in the capillary tube 18 is heated to a temperature sufficient to at least partially volatilize the pre-vaporization preparation in the capillary tube 18.

In at least one embodiment, at least two electrical leads 26 are coupled to the metal capillaries 18. In at least one embodiment, one electrical lead 26 is coupled to the first upstream portion 101 of the capillary tube 18 and the second electrical lead 26 is coupled to the downstream end 102 of the capillary tube 18.

During operation, when the adult vapor aspirator sucks the e-vaping device, the smoke-absorbing sensor 16 detects the pressure gradient generated by the smoke-absorbing of the adult vapor aspirator, and the control circuit 11 activates the heater 19 to activate the storage unit 14. Heat the pre-vaporized formulation located inside. When the capillary tube 18 is heated, the pre-vaporization preparation contained in the heated portion of the capillary tube 18 is volatilized and emerges from the outlet 63, where the pre-vaporization preparation expands, mixes with air, and vaporizes in the mixing chamber 240. Form.

The power supply 12 of the exemplary embodiment may include a battery located within a second section 72 of the e-vaping device 60. The power supply 12 is configured to apply a voltage to both ends of the heater 19, and the heater 19 volatilizes the pre-vaporized preparation contained in the storage unit 14.

In at least one embodiment, the electrical contacts or connections between the heater 19 and the electrical leads 26 are substantially conductive and temperature resistant, while the heater 19 is substantially resistant and thus generate heat. Occurs mainly along the heater 19 rather than the contacts.

The power source or battery 12 may be rechargeable and may include a circuit that allows the battery to be charged by an external charging device. In that case, the circuit may provide power for a predetermined number of smoke absorptions when charged, after which the circuit may need to be reconnected to an external charging device.

In at least one embodiment, the e-vaping device 60 may include a control circuit that can be mounted on the printed circuit board 11. The control circuit 11 may also include a heater actuating light 27 configured to emit light when the heater 19 is activated. In at least one embodiment, the heater actuating light 27 comprises at least one LED and has a cap at the distal end 28 of the e-vaping device 60 in the appearance of coal that the heater actuating light 27 burns during smoke absorption. Try to illuminate. Further, the heater actuating light 27 may be configured to be visible to an adult vapor aspirator. The light 27 can also be configured to allow an adult vapor aspirator to enable, disable, or both enable and disable the light 27, if desired. The light 27 will optionally be disabled during vaporization.

In at least one embodiment, the e-vaping device 60 further comprises a mouth-side end insert 20 having a bifurcation outlet 21 separated from at least two axes. In at least one embodiment, the mouth end insert 20 comprises at least two bifurcated outlets 21 (eg, 3-8 or more outlets). In at least one embodiment, the outlet 21 of the mouth end insert 20 is located at the end of the passage 23 away from the axis and has an outward angle with respect to the major axis direction of the e-vaping device 60 (ie,). Branched). As used herein, the term "off axis" means having an angle with respect to the major axis direction of the e-vaping device. Also, the mouth-side end insert (or flow guide) 20 is an outlet that is evenly distributed around the mouth-side end insert 20 so that the vapor is substantially evenly distributed to the mouth of an adult vapor aspirator during use. May include.

In at least one embodiment, the e-vaping device 60 is about the same size as a conventional cigarette. In some embodiments, the e-vaping device 60 is about 80 mm to about 110 mm long, eg, about 80 mm to about 100 mm long, and about 7 mm to about 10 mm in diameter. You may.

The outer cylindrical housing 22 of the e-vaping device 60 may be formed from or may include any suitable material or combination of materials. In at least one embodiment, the outer cylindrical housing 22 is at least partially made of metal and is part of an electrical circuit connecting the control circuit 11, the power supply 12, the smoke absorption sensor 16 and the heater 19. ..

FIG. 3 is a cross-sectional view of an e-vaping device according to an exemplary embodiment. As shown in FIG. 3, the e-vaping device 60 may also include an intermediate section (third section) 73 capable of accommodating the liquid pre-vaporized product storage 14 and the heater 19. The intermediate section 73 is fitted to the threaded joint 74'at the upstream end of the first section or cartomizer 70 and to the threaded joint 74'at the downstream end of the second section 72. Can be configured in. In this exemplary embodiment, the first section or cartomizer 70 houses the mouth end insert 20, while the second section 72 is configured to control the power supply 12 and the power supply 12. Contain 11 and.

In at least one embodiment, the first section or cartomizer 70, the second section 72, and the third section 73 have a common outer cylinder extending longitudinally along the length of the e-vaping device 60. Includes housing 22. Further, in at least one embodiment, the intermediate section 73 is disposable and one or both of the first section or the cartomizer 70 and the second section 72 can be reused. The sections 70, 72, 73 can be attached by screw connections or connectors 74 and 74', which allows the intermediate section 73 to be replaced when the reservoir 14 is used up. In another embodiment, the first section or cartomizer 70 is replaceable so as to avoid the need to clean one or both of the capillaries 18 and the heater 19. In at least one embodiment, the first section or cartomizer 70 and the second section 72 and the third section 73 may be integrally formed without screw connections to form a disposable e-vaping device. ..

In the exemplary embodiment illustrated in FIG. 3, the reservoir 14 is a tubular elongated body made of or comprising an elastomeric material that is flexible or compressible when compressed. Or both. In at least one embodiment, the elastomeric material can be one of silicone, plastic, rubber, latex, and combinations thereof.

In at least one embodiment, the reservoir 14 fluidly communicates with the capillaries 18 so that when the reservoir 14 is compressed, a volume of pre-vaporized formulation (such as a liquid material) can be delivered to the capillaries 18. At the same time as delivering the pre-vaporized formulation to the capillaries, when manual pressure is applied to the reservoir 14, the power supply 12 is activated and the capillaries 18 are heated to form a heated section in which the pre-vaporized formulation volatilizes. When released from the heated capillaries 18, the volatilized material expands and mixes with air to form vapors.

As shown in FIG. 3, the storage unit 14 is configured to maintain the liquid pre-vaporized preparation in the storage unit 14 and to open when the storage unit 14 is compressed and pressure is applied to the storage unit 14. Includes the valve 40. In at least one embodiment, the valve 40 opens when the critical minimum pressure is reached to prevent inadvertent delivery of the pre-vaporized formulation from the reservoir 14 or activation of the heater 19. In at least one embodiment, the pressure required to press the pressure switch 44 is high enough to avoid unintended heating. Such a configuration avoids the heater 19 from activating in the absence of the pre-vaporizing agent delivered through the capillaries.

When the pressure on the reservoir 14 is relieved, the valve 40 closes and the heated capillaries 18 release any residual pre-vaporization formulation downstream of the valve 40.

In at least one embodiment, the strength enhancer or additive may include cinnamon aldehyde, menthone, eugenol, zingerone, or vanillyl acetone, and gingerol. Strength enhancers also include capsicum, allyl isothiocyanate, piperine, isoeugenol, carvacrol, thymol, menthol, monomenthol succinate, and N- (2-hydroxyethyl) -2,3-dimethyl-2-isopropylbutaneamide. It may be included. Strength enhancers include transient receptor potential cation channels, subfamily A, member 1 (TRPA1), transient receptor potential cation channels, subfamily V, member 1 (TPRV1), or members within adult vapor aspirators. Contains one or more compounds that activate receptors in the respiratory system of adult vapor aspirators, such as the nicotinic acetylcholine receptor, which becomes part of the particle phase and is an adult vapor aspirator during vaporization. It is carried with the particle phase in the airway.

In at least one embodiment, the above compounds as well as others can be found in the extracts, such as horse radish oil, garlic extract, onion oil, black pepper, red pepper. , Ginger oil, thyme oil, cinnamon oil, turmeric, coloha, cardamon, rosemary extract, grapefruit oil, and andrography extract.

In at least one embodiment, the pre-vaporization formulation may contain one or more strength enhancers in a composition range of about 0.0001 percent to about 1 percent, at a concentration of up to about 2 percent, or multiple strength enhancers. When it is a combination of strength enhancers, it may be contained in concentrations greater than about 2 percent and less than about 5 percent. These strength enhancers may activate receptors in the respiratory system of adult vapor aspirators.

In at least one embodiment, the e-vaping device pre-vaporization formulation (eg, liquid formulation, etc.) is one of a vapor-forming body, one or more strength enhancers, nicotine, one or more acids, and water. Contains the above mixture.

The pre-vaporization formulation optionally contains water. The water may be contained in an amount in the range of about 5% by weight to about 40% by weight based on the weight of the pre-vaporized preparation. For example, water may be included in an amount of about 20% by weight based on the weight of the pre-vaporized preparation.

The following examples illustrate various combinations of strength enhancers and the corresponding concentrations. The amount of nicotine in the various formulations may be from about 0.5% to about 1.5% or from about 0.5% to about 2%. Various strength enhancers have been considered above. The acids considered below include pyruvate, formic acid, oxalic acid, glycolic acid, acetic acid, isovaleric acid, valeric acid, propionic acid, octanoic acid, lactic acid, sorbic acid, malic acid, tartaric acid, succinic acid and citric acid. , Savor acid, oleic acid, aconitic acid, butyric acid, silicic acid, decanoic acid, 3,7-dimethyl-6-octenoic acid, 1-glutamic acid, heptanic acid, hexanic acid, 3-hexaneic acid, trans-2-hexane Of acids, isobutyl acid, lauric acid, 2-methylbutyric acid, 2-methylvaleric acid, myristic acid, nonanoic acid, palmitic acid, 4-pentenoic acid, phenylacetic acid, 3-phenylpropionic acid, hydrochloric acid, phosphoric acid, and sulfuric acid. At least one of them can be mentioned. The following examples of the pre-vaporized formulation are considered.

Example 1: Pre-vaporization formulation solutions are approximately a few ppm or about 0.001 percent to about 0.1 percent strength enhancer or additive and about 60 percent to about 80 percent vapor-forming (eg, substantially). (Equal concentrations of propylene glycol and glycerol), about 10 percent to about 20 percent water, about 0.5 percent to about 2 percent weight-based nicotine (NBW), and up to about 5 percent acid. ..

Example 2: Pre-vaporization solution is about 1 percent strength enhancer or additive, about 60 percent to about 80 percent vapor form (eg, propylene glycol and glycerol), and about 15 percent to about 20 percent. Contains about 1 percent to about 2 percent weight-based nicotine (NBW) and up to about 3 percent acid.

Example 3: Pre-vaporization solution is about 15 percent to about 15 percent with about 1.5 percent strength enhancer or additive and about 60 percent to about 80 percent vapor forming material (eg, propylene glycol and glycerol). It contains 20 percent water, about 0.5 percent to about 1.5 percent weight-based nicotine (NBW), and up to about 1 percent acid.

Example 4: Pre-vaporization formulation solution is about 2 percent strength enhancer or additive, about 60 percent to about 80 percent vapor form (eg, propylene glycol and glycerol), and about 15 percent to about 20 percent. Contains about 0.5 percent to about 2 percent weight-based nicotine (NBW) and substantially 0 percent or about 0.1 percent acid.

Example 5: Pre-vaporization solution with a combination of multiple strength enhancers or additives of about 2 percent to about 5 percent and about 60 percent to about 80 percent vapor-forming bodies (eg, propylene glycol and glycerol). , Approximately 15 percent to approximately 20 percent water, and approximately 0.5 percent to approximately 2 percent weight-based nicotine (NBW), and substantially 0 percent or approximately 0.1 percent acid.

Example 6: Pre-vaporization solution is one of about 0.1 percent cinnamon aldehyde, menton, eugenol, zingerone or vanillyl acetone, and gingerol, and about 60 percent to about 80 percent vapor-forming (eg, for example). It contains (propylene glycol and glycerol), about 15 percent to about 20 percent water, about 0.5 percent to about 2 percent weight-based nicotine (NBW), and up to about 5 percent acid.

Example 7: The prevaporative preparation solution is one or more of about 1 percent cinnamon aldehyde, menton, eugenol, zingerone or vanillyl acetone, and gingerol, and about 60 percent to about 80 percent vapor-forming (eg,). , Propylene glycol and glycerol), about 15 percent to about 20 percent water, about 0.5 percent to about 2 percent weight-based nicotine (NBW), and up to about 3 percent acid.

Example 8: Pre-vaporization solution is about 1.5 percent katsura aldehyde, menton, eugenol, zingerone or vanillyl acetone, and one or more of gingerol and about 60 percent to about 80 percent vapor-forming. It contains (eg, propylene glycol and glycerol), about 15 percent to about 20 percent water, about 0.5 percent to about 2 percent weight-based nicotine (NBW), and up to about 1 percent acid. Alternatively, the pre-vaporization formulation comprises about 1.5 percent cinnamon aldehyde, menthone, eugenol, zingerone or vanillyl acetone, and a combination of two or more of gingerol.

Example 9: Pre-vaporization solution is a combination of about 2 percent cinnamon aldehyde, menton, eugenol, zingerone or vanillyl acetone, and gingerol, and about 60 percent to about 80 percent vapor-forming (eg, propylene glycol and). Glycerol), about 15 percent to about 20 percent water, about 0.5 percent to about 2 percent weight-based nicotine (NBW), and substantially 0 percent acid.

Example 10: Pre-vaporization solution is a vapor-forming solution of about 60 percent to about 80 percent with two or more of katsura aldehyde, menton, eugenol, zingerone or vanillyl acetone, and gingerol in excess of about 2 percent. For example, propylene glycol and glycerol), about 15 percent to about 20 percent water, about 0.5 percent to about 2 percent weight-based nicotine (NBW), and substantially 0 percent acid. Alternatively, the pre-vaporization formulation comprises a combination of two or more of cinnamon aldehyde, menthone, eugenol, zingerone or vanillyl acetone, and gingerol in excess of about 2 percent.

Example 11: Pre-vaporization solution is about 0.1 percent to about 2.5 percent horse radish oil, garlic extract, onion oil, black pepper, red pepper, ginger oil, thyme oil, katsura oil, turmeric, A combination of coloha, cardamon, rosemary extract, grapefruit oil and andrography extract, about 60 percent to about 80 percent vapor form (eg, propylene glycol and glycerol), and about 15 percent to about 20 percent water. It contains about 0.5 percent to about 2 percent weight-based nicotine (NBW) and up to about 5 percent any amount of acid.

Example 12: Pre-vaporization formulation solutions for non-smoking devices include about 0.1 percent to about 2 percent strength enhancers or additives and about 60 percent to about 80 percent vapor-forming bodies (eg, propylene glycol and glycerol). ), About 10 percent to about 20 percent water, about 0.5 percent to about 2 percent weight-based nicotine (NBW), and about 0.1 percent to about 5 percent acid.

In at least one embodiment, the acid acts to reduce the amount of perceived throat thorniness when the vapor is produced from the pre-vaporized formulation with the operation of the e-vaping device, while the vapor's. The strength enhancer works as the vapor increases the perceived strength.

According to at least one exemplary embodiment, the acid has the ability to transform into a vaporized formulation. The acid evaporation efficiency is the ratio of the mass fraction of acid in the vaporized formulation to the mass fraction of acid in the pre-vaporized formulation. In at least one embodiment, the acid has a pre-vaporization formulation having an evaporation efficiency of about 50 percent or more, eg, about 60 percent or more. For example, the evaporation efficiency of pyruvic acid, lactic acid, oxalic acid, acetic acid, and glycolic acid is about 50 percent or more. In at least one embodiment, the pre-vaporization formulation comprises an acid having an evaporation efficiency of about 50 percent or more. In another embodiment, the pre-vaporization formulation does not contain any acid with an evaporation efficiency of about 25 percent or less.

According to at least one exemplary embodiment, the acid has a boiling point of at least about 100 ° C. and is included in the pre-vaporization formulation in an amount sufficient to adjust the pH of the pre-vaporization formulation to the range of about 3 to about 8. It can be.

According to at least one exemplary embodiment, the prevaporative preparations are pyruvate, formic acid, oxalic acid, glucolic acid, acetic acid, isovaleric acid, valeric acid, propionic acid, octanoic acid, lactic acid, sorbic acid, malic acid, Tartrate acid, succinic acid, citric acid, benzoic acid, oleic acid, aconitic acid, butyric acid, silicic acid, decanoic acid, 3,7-dimethyl-6-octenoic acid, 1-glutamic acid, heptanic acid, hexane acid, 3-hexane Acid, trans-2-hexanoic acid, isobutyl acid, lauric acid, 2-methylbutyric acid, 2-methylvaleric acid, myristic acid, nonanoic acid, palmitic acid, 4-pentenoic acid, phenylacetic acid, 3-phenylpropionic acid, hydrochloric acid , Phosphoric acid, sulfuric acid, and one or more of combinations thereof. The acid may also be incorporated in the form of a salt. The pre-vaporization formulation also contains vapor-forming bodies, optionally water, nicotine, and flavoring agents.

Accordingly, exemplary embodiments have been described and it will be clear that they can be modified in many ways. Such modifications should not be considered as deviating from the intended scope of the exemplary embodiments, and all of these modifications, as would be apparent to one of ordinary skill in the art, are within the scope of the following claims. Intended to be included.

Claims (20)

It is a pre-vaporization preparation for an e-vaping device, and the pre-vaporization preparation is
A vapor-forming body containing at least one of propylene glycol and glycerol,
A pre-vaporization preparation comprising an additive containing at least one of carvacrol, thymol, monomentyl succinate, N- (2-hydroxyethyl) -2,3-dimethyl-2-isopropylbutaneamide. The pre-vaporization preparation according to claim 1, further comprising nicotine. The pre-vaporization preparation according to claim 1 or 2, wherein the additive further comprises at least one of piperine, allyl isothiocyanate, capsicum, isoeugenol, and menthol. The additive is an extract from at least one of gingerlon, garlic extract, onion oil, thyme oil, cinnamon oil, turmeric, coloha, cardamon, rosemary extract, grapefruit oil, and andrography extract. , The pre-vaporization preparation according to claim 1, 2 or 3. 13. Pre-vaporization preparation. The pre-vaporization preparation according to any one of claims 1 to 5, wherein the concentration of the additive is 0.0001% to 1%. The pre-vaporization preparation according to any one of claims 1 to 6, wherein the concentration of the combination of the plurality of additives in the pre-vaporization preparation is higher than 2%. The pre-vaporization preparation according to claim 7, wherein the concentration of the combination of the plurality of additives in the pre-vaporization preparation is 2% to 5%. The pre-vaporization preparation according to claim 2, wherein the concentration of nicotine in the vapor phase of the vapor-forming body is 1% or less. The pre-vaporization preparation according to claim 2 or 9, wherein the concentration of nicotine is in the range of 0.5% by weight to 2% by weight. The pre-vaporization preparation according to any one of claims 1 to 10, wherein the vapor-forming body contains substantially equal concentrations of propylene glycol and glycerin. The pre-vaporization preparation according to any one of claims 1 to 11, further comprising water having a concentration of 10% to 20%. The pre-vaporization preparation according to any one of claims 1 to 12, further comprising an acid having a concentration of 0.1% to 5%. The acids are pyruvate, formic acid, oxalic acid, glycolic acid, acetic acid, isovaleric acid, valeric acid, propionic acid, octanoic acid, lactic acid, sorbic acid, malic acid, tartrate acid, succinic acid, citric acid, benzoic acid, oleic acid. , Aconytic acid, butyric acid, silicic acid, decanoic acid, 3,7-dimethyl-6-octenoic acid, 1-glutamic acid, heptanic acid, hexaneic acid, 3-hexaneic acid, trans-2-hexaneic acid, isobutyl acid, laurin At least one of acid, 2-methylbutyric acid, 2-methylvaleric acid, myristic acid, nonanoic acid, palmitic acid, 4-pentenoic acid, phenylacetic acid, 3-phenylpropionic acid, hydrochloric acid, phosphoric acid, and sulfuric acid. The prevaporative preparation according to claim 13, which comprises. The pre-vaporization preparation according to claim 13 or 14, wherein the evaporation efficiency of the acid is higher than 50%. It ’s an e-vaping device.
With a cartomizer, which includes a reservoir for holding the pre-vaporized product, a mouse end piece, and a heater configured to heat the pre-vaporized product.
A smoke-absorbing sensor connected to the cartomizer and configured to detect smoke absorption performed by the mouse end piece, and a power supply section including a power supply source configured to supply power to the heater. Prepare,
The pre-vaporization preparation
Vapor-forming bodies containing a combination of propylene glycol and glycerol,
An e-vaping apparatus comprising an additive containing at least one of carvacrol, thymol, monomentyl succinate, N- (2-hydroxyethyl) -2,3-dimethyl-2-isopropylbutaneamide. The e-vaping device according to claim 16, wherein the pre-vaporization preparation further comprises nicotine. The additive is an extract from at least one of gingerlon, garlic extract, onion oil, thyme oil, cinnamon oil, turmeric, coloha, cardamon, rosemary extract, grapefruit oil, and andrography extract. , The e-vaping device according to claim 16 or 17. At least one of the concentration of the additive being in the range of 0.0001% to 1% and the concentration of the combination of the plurality of additives in the pre-vaporization preparation being higher than 2%. , The e-vaping device according to claim 16, 17 or 18. The concentration of nicotine in the vapor phase of the vapor-forming body is 2% or less.
The pre-vaporization formulation further comprises a concentration of 10% to 20 percent water, and the pre-vaporization formulation further comprises a concentration of 0.1 percent to 5 percent acid, and the evaporation efficiency of the acid is greater than 50 percent. The e-vaping device according to any one of claims 16 to 19, which is at least one of the high prices.

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