JP2022087249A - Oil-in-water emulsion composition - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain an oil-in-water emulsion composition that contains nicotinamide, is effective in imparting firmness and resilience to the skin, has a good feeling in use with no stickiness, reduces powdering of nicotinamide after moisture transpiration, and yet has excellent emulsion stability.

SOLUTION: An oil-in-water emulsion composition contains following components (A)-(F): (A) nicotinamide of 1-10 mass%, (B) phospholipid of 0.1-2 mass%, (C) a nonionic surfactant with an HLB of 7 or more of 0.02-1 mass%, (D) an oil solution which is liquid at 25°C, (E) polyhydric alcohol of 5-20 mass%, and (F) water.

SELECTED DRAWING: None

COPYRIGHT: (C)2022,JPO&INPIT

Description

INDUSTRIAL APPLICABILITY The present invention not only improves the firmness and elasticity of the skin and gives an excellent feeling of use without stickiness, but also reduces the powder blowing of nicotinamide after water evaporation, while having excellent emulsification stability. It relates to a mold emulsified composition.

The skin causes stains, wrinkles, sagging, pigmentation, etc. due to internal factors such as aging and stress, and external factors such as ultraviolet rays and dry air. Among them, morphological changes such as wrinkles and sagging greatly affect the impression of appearance, so many people want to improve it. Many drugs have been proposed to prevent and improve these wrinkles and sagging. Under these circumstances, nicotinamide is a vitamin and is known to be highly safe and have an anti-aging effect on the skin (Patent Documents 1 and 2). However, it is known that when a large amount of nicotinamide is contained, there is an undesired feeling of use such as stickiness, and this improvement has been made (Patent Document 3).

Japanese Unexamined Patent Publication No. 10-130135 Japanese Unexamined Patent Publication No. 10-1414 Special Table 2003-502435 Gazette

Patent Document 3, which attempts to suppress the stickiness of nicotinic acid amide, is a technique containing both a branched chain hydrocarbon and a highly expandable oil such as a liquid ester emollient, but its effect is insufficient. , There was a problem that creaming occurred over time when the oil-in-water emulsion composition was prepared.
Further, in a composition containing a large amount of nicotinamide, when a volatile component such as water is blended, nicotinamide precipitates as crystals as the water evaporates, and powder blowing occurs. Was newly discovered. This powder blowing of nicotinamide occurred, for example, in a place accompanied by water evaporation over time, particularly around the mouth of the container or near the protrusion mechanism of the dispenser. When powder blowing of nicotinamide occurs around the mouth of the container, nicotinamide crystals are mixed when the cosmetic is taken out from the mouth of the container, and the usability is remarkably poor. Further, when the powder blowing of nicotinamide occurs in the vicinity of the protrusion mechanism of the dispenser, the root is clogged in the mechanism, which leads to the problem that the cosmetic cannot be projected.

In view of such circumstances, the present inventors have conducted intensive studies to solve the above-mentioned problems, and as a result, surprisingly, phospholipids are contained in a high concentration of 1 to 10% by mass of nicotinic acid amide. It was found that the simultaneous inclusion of polyhydric alcohol and polyhydric alcohol can suppress the crystal precipitation of nicotinic acid amide after water evaporation and improve powder blowing.
On top of that, a nonionic surfactant containing nicotinic acid amide in a high concentration of 1 to 10% by mass, phospholipid 0.1 to 2% by mass, and HLB of 7 or more 0.02 to 1% by mass, 25. An oil-in-water emulsified composition containing an oil agent that is liquid at ° C, a polyhydric alcohol of 5 to 20% by mass, and water has an excellent effect of imparting elasticity and elasticity to the skin, and has good emulsification stability over time. It has been found that the stickiness during use is reduced and the powder blowing of nicotinic acid amide after water evaporation is further improved, and the present invention has been completed.

That is, in the present invention, the following components (A) to (F):
(A) Nicotinamide 1-10% by mass
(B) Phospholipid 0.1-2% by mass
(C) Nonionic surfactant having an HLB of 7 or more 0.02 to 1% by mass
(D) Oil agent liquid at 25 ° C. (E) Polyhydric alcohol 5 to 20% by mass
(F) An oil-in-water emulsified composition containing water is provided.

In the present invention, the component (C) may be one or more selected from polyoxyethylene castor oil, polyoxyethylene alkyl ether phosphoric acid, polyoxyethylene phytosterol ether, and polyoxyethylene cholesteryl ether.
The present invention may further contain a solid or semi-solid higher alcohol at component (G) 25 ° C.
In the present invention, the content mass ratio (A) / ((B) + (C)) of the component (A) to the component (B) and the component (C) may be 1 to 10.
In the present invention, the content mass ratio (A) / ((D) + (E)) of the component (A) to the component (D) and the component (E) may be 0.05 to 0.5. ..
The oil-in-water emulsified composition of the present invention may be a cosmetic or a skin external preparation.

The oil-in-water emulsified composition of the present invention improves the firmness and elasticity of the skin, has good emulsification stability over time, and further improves stickiness during use and powder blowing of nicotinamide after water evaporation. It is a thing.

Hereinafter, the present invention will be described in detail. In addition, in this specification, "-" shall mean the range including the numerical values before and after it. In addition, the numerical value expressed in% is a value based on the mass unless otherwise specified.

Component (A): Nicotinamide The component (A) nicotinamide in the present invention is an amide compound of nicotinic acid (vitamin B3 / niacin). Nicotinamide is a water-soluble vitamin, which is a known substance that is one of the B vitamins, and can be extracted from natural products (rice bran, etc.) or synthesized by a known method. Specifically, those listed in the 15th revised Japanese Pharmacopoeia 2008 can be used.

In the present invention, the content of the component (A) is 1 to 10% by mass (hereinafter, simply "mass%" is abbreviated as "%") in order to improve the firmness and elasticity of the skin and suppress stickiness, and 3 -10% is preferable, and 4-9% is particularly preferable. If the content of the component (A) is less than 1%, the effect of imparting elasticity and elasticity to the skin is not excellent, and if it exceeds 10%, the skin becomes very sticky and the feeling of use is poor.

Component (B): Phospholipid Unless otherwise specified, the phospholipid of the component (B) used in the present invention has glycerin or sphingocin as a central skeleton to which fatty acid and phosphoric acid are bound, and further, alcohol is ester-bonded to phosphoric acid. It means the one with the structure. Examples of the fatty acid constituting the phospholipid include saturated and unsaturated carboxylic acids having 7 to 22 carbon atoms. Nitrogen is often contained as an alcohol constituting a phospholipid, and examples thereof include choline, ethanolamine, inositol, and serine. The present invention includes soy lecithin extracted from natural soybeans and egg yolks, egg yolk lecithin and / or hydrogenated lecithin (hydrousated lecithin) obtained by hydrogenating these, hydrogenated soy lecithin, hydrogenated egg yolk lecithin, synthetic phospholipids and the like. What is commonly known as phospholipids can be used. More specifically, phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, phosphatidic acid, phosphatidylinositol and the like can be preferably used. From these, one kind or two or more kinds can be used.
Specific examples thereof include hydrogenated soybean phospholipids, hydrogenated egg yolk phospholipids, hydrogenated phosphatidylcholine, hydrogenated phosphatidylserine, and lysophospholipids having one fatty acid group removed from the phospholipids, which may be hydrogenated. It may be a hydrogenated lysophospholipid. Examples of commercially available hydrogenated phospholipids include Resinol S-10, Resinol S-10EZ, Resinol S-10M, Resinol S-10EX, Resinol S-PIE (all manufactured by Nikko Chemicals), COATSOME NC-21 (NOF). , Phosphoripon100H, Phosphoripon90H, Phosphoripon80H, Phosphoripon90G (all manufactured by Phospholipid) and the like. Examples of hydrogenated lysophospholipids include LP70H (manufactured by Nippon Fine Chemical Co., Ltd.), SLP-White ResoH, SLP-LPC 70H (manufactured by Tsuji Oil Co., Ltd.) and the like.

In the present invention, the content of the component (B) is 0.1 to 2% from the viewpoint of improving the firmness and elasticity of the skin, improving the stickiness and improving the emulsification stability, and further 0.1. It is preferably ~ 1.5%, more preferably 0.15 ~ 1%. If the content of the component (B) is less than 0.1%, the effect of imparting elasticity and elasticity to the skin is not excellent, and the emulsification stability is deteriorated. Further, when the content of the component (B) exceeds 2%, the stickiness at the time of use is severe and the usability is poor.

Component (C): Nonionic surfactant having an HLB of 7 or more The nonionic surfactant having an HLB of 7 or more of the component (C) in the present invention is an important component for efficiently emulsifying an oily component. When the HLB of the nonionic surfactant is less than 7, the emulsion stability is not excellent and the stickiness during use is also large. In order to further improve the emulsion stability, the HLB is preferably 7 to 19, more preferably 8 to 18, and particularly preferably 9 to 18.
Here, the HLB (Hydfile-Lipophilic Balance) in the present invention is an index showing the balance between hydrophilicity and lipophilicity, and is calculated by the following (formula 1) by Oda and Teramura et al.
HLB = (Σ inorganic value / Σ organic) × 10 ... (Equation 1)
Here, the Σ-inorganic value / Σ-organic is called IOB (Inorganic-Organic balance), and the surface activity is based on the "inorganic value" and "organic value" set for each of various atoms and functional groups. It can be calculated by integrating the "inorganic values" and "organic values" of the atoms and functional groups that make up organic compounds such as agents (Yoshio Koda, "Organic Conceptual Diagram-Basics and Applications-", See pages 11-17, Sankyo Publishing, 1984).
The nonionic surfactant having an HLB of 7 or more is not particularly limited, and specific examples thereof include polyglyceryl fatty acid ester, polyoxyethylene castor oil, polyoxyethylene sorbitan monostearate, and polyoxyethylene sorbitan monooleate. Polyoxyethylene sorbitan fatty acid ester, polyoxyethylene glyceryl monooleate, polyoxyethylene glyceryl fatty acid ester such as polyoxyethylene glyceryl monoisostearate, polyethylene glycol fatty acid ester such as polyethylene glycol monoisostearate, polyoxyethylene alkyl Ether, polyoxyethylene alkyl ether phosphoric acid, polyoxypropylene alkyl ether, polyoxypropylene alkyl ether phosphoric acid, polyoxyethylene alkylphenyl ether, polyoxyethylene phytostanol ether, polyoxyethylene phytosterol ether, polyoxyethylene cholestanol ether , Polyoxyethylene cholesteryl ether, polyoxyalkylene modified organopolysiloxane and other polyoxyethylene-added nonionic surfactants, and these can be used alone or in combination of two or more. Among these, polyoxyethylene castor oil derivative, polyoxyethylene alkyl ether phosphoric acid, polyoxyethylene phytosterol ether, and polyoxyethylene are obtained in that they can improve stickiness during use and maintain good emulsion stability. One or more selected from cholesteryl ether is preferable, and one or more selected from polyoxyethylene phytosterol ether and polyoxyethylene cholesteryl ether are particularly preferable.
Polyoxyethylene castor oil is a castor oil or hydrogenated castor oil to which oxyethylene is added, or a compound to which fatty acid is further added (hereinafter, polyoxyethylene is referred to as POE, and the numerical values in parentheses indicate it. , May indicate the average number of moles of oxyethylene added). The polyoxyethylene castor oil is not particularly limited as long as it has an HLB of 7 or more, but specifically, POE (10) cured castor oil, POE (20) cured castor oil, and POE (30) cured castor oil. , POE (40) Hardened castor oil, POE (50) Hardened castor oil, POE (60) Hardened castor oil, POE (80) Hardened castor oil, POE (100) Hardened castor oil, Monoisostearic acid POE (50) Hardened castor Examples include oil, and one or more of these can be appropriately selected and used depending on the purpose. It is preferable to select one to which 20 to 50 mol of polyoxyethylene is added, and more preferably POE (40) hardened castor oil, in that the stickiness can be further improved and the stability over time can be maintained better. One or more selected from POE (50) hardened castor oil monoisostearate.
Polyoxyethylene alkyl ether phosphoric acid is a triester compound of polyoxyethylene alkyl ether and phosphoric acid. The polyoxyethylene alkyl ether phosphoric acid is not particularly limited as long as it has an HLB of 7 or more, but the fatty acid chain length is preferably in the range of 8 to 22 carbon atoms, and more preferably 10 to 18 carbon atoms. The fatty acid may be saturated or unsaturated, and may be linear or branched. The polyoxyethylene chain is preferably in the range of 1 to 20, more preferably in the range of 2 to 12. For example, polyoxyethylene lauryl ether phosphoric acid, polyoxyethylene myristyl ether phosphoric acid, polyoxyethylene cetyl ether phosphoric acid, polyoxyethylene stearyl ether phosphoric acid, polyoxyethylene oleyl ether phosphoric acid, polyoxyethylene behenyl ether phosphoric acid, Examples thereof include polyoxyethylene alkyl (10-15) ether phosphoric acid, polyoxyethylene dialkyl (12-15) ether phosphoric acid, polyoxyethylene tricetyl ether phosphoric acid, polyoxyethylene tristearyl ether phosphoric acid, and the like. It may be used alone or in combination of two or more. Among these, one or more selected from polyoxyethylene cetyl ether phosphoric acid and polyoxyethylene stearyl ether phosphoric acid are available in that they can further improve stickiness and maintain better stability over time. preferable.
Polyoxyethylene phytosterol ether and polyoxyethylene cholesteryl ether refer to compounds in which phytosterol and cholesterol are ether-bonded to polyoxyethylene, respectively. As long as the HLB is 7 or more, there is no particular limitation, but more specifically, as the polyoxyethylene phytosterol ether, POE (5) phytosterol, POE (10) phytosterol, POE (20) phytosterol, POE (25) phytosterol and Examples thereof include POE (30) phytosterols, and examples of the polyoxyethylene cholesteryl ether include POE (10) cholesteryl ether, POE (15) cholesteryl ether, POE (20) cholesteryl ether, POE (24) cholesteryl ether and POE (30) cholesteryl ether. Examples thereof include ether, and these can be used alone or in combination of two or more, if necessary. Among these, POE (5) phytosterol, POE (10) phytosterol, POE (20) phytosterol, POE (25) phytosterol, POE can further improve stickiness and maintain better stability over time. (30) One or more selected from phytosterol, POE (10) cholesteryl ether, and POE (15) cholesteryl ether are preferable.

The content of the component (C) is 0.02 to 1%, preferably 0.02 to 0.8%, and more preferably 0.03 to 0, from the viewpoint of improving stickiness and emulsification stability. It is 0.7%, more preferably 0.04 to 0.6%. If the content of the component (C) is less than 0.02%, the effect of imparting elasticity and elasticity to the skin is not excellent, and the emulsification stability is deteriorated. Further, when the content of the component (B) exceeds 1%, the stickiness at the time of use is severe and the usability is poor.

Component (D): An oil agent that is liquid at 25 ° C. The "liquid" of the oil agent that is liquid at 25 ° C. of the component (D) in the present invention is a B-type viscometer (rotor No.) at 25 ° C. and 1 atm. It refers to a viscosity value of 7,000 mPa · s or less as measured in 2). The oil agent that is liquid at 25 ° C. is not particularly limited, and is an ester oil that includes hydrocarbons, oils and fats, and ultraviolet absorbers regardless of the origin of volatile, non-volatile oils, animal oils, vegetable oils, synthetic oils, and the like. Classes, fatty acids, higher alcohols, silicone oils, fluorooils, lanolin derivatives and the like.

Specifically, fats and oils such as olive oil, castor oil, minced oil, macadamian nut oil, avocado oil, and medfoam oil, jojoba oil, diisobutyl adipate, 2-hexyldecyl adipate, and di-2-heptyl adipate. Undecyl, Alkyl Glycol Monoisostearate, Isocetyl Isostearate, Trimethylol Propane Triisostearate, Ethylene Glycol Di-2-ethylhexarate, Neopentyl Glycol Di-2-ethylhexanoate, Trimethylol Tri-2-ethylhexarate Propane, pentaerythritol tetra-2-ethylhexanoate, cetyl 2-ethylhexanoate, oleyl oleate, octyldodecyl oleate, decyl oleate, neopentyl glycol dicaprate, triethyl citrate, 2-ethylhexyl succinate, stearate Isocetyl, butyl stearate, diisopropyl sebacate, di-2-ethylhexyl sebacate, cetyl lactate, myristyl lactate, isopropyl palmitate, 2-ethylhexyl palmitate, 2-hexyldecyl palmitate, 2-heptyl undesyl palmitate, di Pentaerythritol fatty acid ester, isononyl isononanoate, isotridecyl isononanoate, isopropyl myristate, isopropyl palmitate, 2-octyldodecyl myristate, 2-hexyldecyl myristate, myristyl myristate, hexyldecyl dimethyloctanoate, ethyl laurate, laurin Hexyl acid, 2-ethylhexyl methoxycinnamate, diisostearyl malate, glyceryl tri-2-ethylhexanoate, glyceryl tri (capril caprin) acid, glyceryl tricaprate, glyceryl triisostearate, diglyceryl diisostearate, tri Diglyceryl isostearate, diglyceryl tetraisostearate, decaglyceryl decisostearate, glyceryl triisopalmitate, glyceryl trimyristate, diglyceryl isostearic myristate, tritridecyl trimeritoate, N-lauroyl-L-glutamate-2- Octyldodecyl esters, esters such as N-lauroyl-L-glutamate di (phytostearyl 2-octyldodecyl), fatty acids such as isothearic acid and oleic acid, higher alcohols such as oleyl alcohol and isostearyl alcohol, and lanolin acetate. , Lanori Polar oils such as fatty acids isopropyl and lanolin derivatives such as lanolin alcohol, low polymerization degree dimethylpolysiloxane, high polymerization degree dimethylpolysiloxane, methylphenylpolysiloxane, decamethylcyclopentasiloxane, octamethylcyclotetrasiloxane, fluorine modification Silicone oils such as organopolysiloxane, fluorooils such as perfluorodecane, perfluorooctane, and perfluoropolyether, isododecane, isohexadecane, light liquid isoparaffin, liquid paraffin, heavy liquid isoparaffin, α-olefin oligomer, Examples thereof include non-polar oils such as hydrocarbons such as squalane, polyisobutylene and polybutene, and one or more of these can be used as required. These can be used alone or in combination of two or more as needed.

The content of the component (D) in the cosmetic of the present invention is not particularly limited, but is preferably 0.1 to 20%, more preferably, from the viewpoint of improving stickiness, improving emulsion stability, and suppressing powder blowing of nicotinamide. Is 0.5 to 10%, more preferably 1 to 5%.

Component (E): Multihydric alcohol The polyhydric alcohol of the component (E) in the present invention is a compound having two or more hydroxyl groups in the molecule. The component (E) is useful for improving the firmness and elasticity of the skin, improving stickiness, improving the emulsification stability over time, and further suppressing powder blowing of nicotinamide. Specifically, the component (E) is a polypropylene glycol such as propylene glycol, dipropylene glycol, or tripropylene glycol, butylene glycol such as 1,3-butylene glycol, 1,4-butylene glycol, or 1,2-pentanediol. , 1,3-Pentanediol, etc., and polyglycerin such as glycerin, diglycerin, triglycerin, tetraglycerin, etc. , Xylitol, sorbitol, maltotriose, slateol, erythritol, polyethylene glycol, polyoxyalkylene alkyl glycoside and other glucose derivatives, and one or more of these can be appropriately selected and used. can. Of these, 1,3-butylene glycol and glycerin are preferable in terms of improving emulsification stability and suppressing powder blowing of nicotinamide during water evaporation.
The content of the component (E) in the cosmetic of the present invention is 5 to 20% in terms of improving stickiness, improving emulsification stability over time, and suppressing powder blowing of nicotinamide during water evaporation. , 7-18%, more preferably 10-18%. If the content of the component (E) is less than 5%, the emulsion stability over time deteriorates, and the powder blowing of nicotinamide during water evaporation cannot be suppressed. When the content of the component (E) exceeds 20%, the emulsification stability with time deteriorates, the stickiness becomes severe, and the usability is poor.

Component (F): Water The water of the component (F) used in the present invention is contained to prepare an oil-in-water emulsified composition, and is not particularly limited as long as it is generally used for cosmetics. In addition to water, purified water, hot spring water, deep water, or steam distilled water of plants may be used, and one or more of them may be appropriately selected and used as needed. The content is not particularly limited, and can be appropriately contained depending on the amount of other components, preferably 30 to 90%.

Component (G): Solid or semi-solid higher alcohol at 25 ° C. The higher alcohol of component (G) in the present invention, solid or semi-solid at 25 ° C., is a solid or semi-solid at 25 ° C. and 1 atm. A saturated or unsaturated linear or branched alcohol represented by ROH (R is an alkyl or alkenyl group). "Semi-solid" means that the viscosity value measured by a B-type viscometer (rotor No. 2) at 25 ° C. and 1 atm is 7000.
Refers to those exceeding mPa · s. Although the component (G) is not an essential component, it is preferable to contain the component (G) in that the emulsion stability is further improved. The component (G) is not particularly limited, but specifically, cetyl alcohol, stearyl alcohol, araquil alcohol, behenyl alcohol (1-docosanol), myristyl alcohol, cetostearyl alcohol, batyl alcohol, kimil alcohol, cholesterol, and phytosterol. And so on. Among these, stearyl alcohol, behenyl alcohol (1-docosanol), cetostearyl alcohol, cholesterol, and phytosterol are preferable in that the emulsified droplets are made finer and the emulsification stability is further improved.

The content of the component (G) in the present invention is not particularly limited, but is 0.005 to 0 in terms of improving stickiness, improving emulsification stability over time, and suppressing powder blowing of nicotinamide during water evaporation. 1% is preferable, 0.01 to 0.8% is more preferable, and 0.02 to 0.5% is even more preferable.

The oil-in-water emulsified composition of the present invention contains the above-mentioned components (A) to (F), and in some cases, the component (G) in a predetermined mass, so that the skin has an excellent effect of imparting elasticity and elasticity over time. The emulsion stability is good, and the stickiness during use and the powder blowing caused by the crystal precipitation of nicotinic acid amide after water evaporation are improved.

Here, in terms of suppressing powder blowing of nicotinamide, the content mass ratio (A) / ((B) + of the component (A) and the component (B) and the component (C) in the oil-in-water emulsified composition (C)) is preferably 1 to 10, more preferably 2 to 9. Further, in terms of suppressing powder blowing of nicotinamide and reducing stickiness during use, the content ratios (A) / ((D) + (E)) of the component (A) and the components (D) and (E) are It is preferably 0.05 to 0.5, more preferably 0.1 to 0.4.

The method for producing an oil-in-water emulsified composition of the present invention can be produced without particular limitation as long as it is a known emulsification method. Specific examples thereof include a dispersion emulsification method, a phase inversion emulsification method, and a phase inversion temperature emulsification method. To exemplify a preferable production method in terms of obtaining an oil-in-water emulsified composition having excellent emulsion stability over time, the components (B), (C), (E), and in some cases, the components ( G) and other oily components are heated and mixed, and then the heated component (D) is added and mixed to emulsify, and then the components (A), (F), and in some cases, other components. Examples thereof include a manufacturing method in which an aqueous component is added and mixed.

In addition to the above components, the oil-in-water emulsified composition of the present invention contains any components contained in ordinary cosmetics as long as the effects of the present invention are not impaired, that is, lower alcohols, and other components other than the component (E). Aqueous component, oil component other than component (B), (D), (G), powder, water-soluble polymer, film-forming agent, surfactant other than component (C), oil-soluble gelling agent, organic modification It can contain clay minerals, resins, colorants, ultraviolet absorbers, preservatives, antibacterial agents, fragrances, antioxidants, pH regulators, chelating agents, beauty ingredients and the like.

The oil-in-water emulsified composition of the present invention can be used in various dosage forms in combination with other components. Specifically, it can be carried out in various dosage forms such as liquid, gel, paste, cream and solid.

The oil-in-water emulsified composition of the present invention can be used as a cosmetic for various purposes. For example, skin lotion, milky lotion, cream, beauty liquid, massage fee, pack fee, hand cream, body lotion, body cream, sunscreen and other skin care cosmetics, foundation, eye shadow, eye liner, mascara, eyebrow, concealer, lipstick. , Lip balm and other finishing cosmetics Hair mist, treatment, hair cream, and other hair cosmetics can be exemplified. Examples of the method of use include a method of using it with a hand, a finger, and cotton, and a method of impregnating it with a non-woven fabric or the like.

The oil-in-water emulsified composition of the present invention can also be used as an external preparation for skin. For example, an external liquid agent, an external gel agent, a cream agent, an ointment agent, a liniment agent, a lotion agent, a hap agent, a plaster agent, a spray agent, an aerosol agent and the like can be mentioned. Further, the method of use thereof can be mentioned in the same manner as the above-mentioned cosmetics.

The present invention will be described in more detail below with reference to examples, but the present invention is not limited thereto. Unless otherwise specified, the content is shown in mass% with respect to the system in which the component is contained.

Examples 1 to 13, Comparative Examples 1 to 14: Oil-in-water emulsification compositions The oil-in-water emulsification compositions having the formulations shown in Tables 1 to 4 below were prepared, and the skin was firm and elastic, non-sticky, and powder-blown. The absence and emulsification stability were evaluated by the following methods. The results are also shown in Tables 1 to 4.

(Production method)
A: The components (7) to (15) and the components (22) to (26) are uniformly dissolved and mixed at 70 ° C.
B: The components (16) to (21) are uniformly dissolved and mixed at 70 ° C.
C: The components (1) to (6) and the components (27) to (32) are uniformly dissolved and mixed at 70 ° C.
D: Emulsification was carried out by adding and mixing B to A, and then C was added and mixed, and then cooled to 40 ° C. to obtain an oil-in-water emulsified composition.

(Evaluation item)
stomach. Skin firmness and elasticity b. No stickiness c. No powder blowing d. Emulsification stability

(Evaluation method)
[About a and b (sensory evaluation)]
We selected 10 specialized panels that were trained in sensory evaluation by women in their 20s and 40s and could be evaluated according to certain criteria. For each sample, the firmness, elasticity, and non-stickiness of the skin that the specialized panel feels when applied to the skin are evaluated on a 5-point scale by the following absolute evaluation and graded, and the total score of all the panels is used for each sample. The average value was calculated and judged according to the following four-step judgment criteria.

(B. Evaluation of skin firmness and elasticity)
Absolute evaluation criteria (score): (evaluation)
6 points: I feel that the skin is very firm and elastic 5 points: I feel that the skin is firm and elastic 4 points: I feel that the skin is slightly firm and elastic 3 points: Normal 2 points: I feel that the skin is too firm・ I do not feel that it is elastic 1 point: I do not feel that my skin is firm ・ I do not feel that it is elastic 4 grade criteria (judgment): (average score)
◎: Exceeding 5 points: Very good ○: Exceeding 3.5 points and 5 points or less: Good △: Exceeding 2 points and 3.5 points or less: Slightly defective ×: 2 points or less: Defect

(B. Evaluation of stickiness)
Absolute evaluation criteria (score): (evaluation)
5 points: No stickiness 4 points: Almost no stickiness 3 points: Somewhat sticky 2 points: Very sticky 1 point: Very sticky 4 grade criteria (judgment): (Average score)
◎: Exceeding 4 points: Very good ○: Exceeding 3 points and 4 points or less: Good △: Exceeding 2 points and 3 points or less: Slightly defective ×: 2 points or less: Defect

(C. Evaluation of no powder blowing)
Apply each sample (1 g / cm ² ) to a plastic petri dish, heat it in a high-temperature incubator at 40 ° C for 24 hours, and confirm the state of the residue on the petri dish by touching it with your finger. Then, the judgment was made according to the following two-step judgment criteria.
Two-step judgment criteria (judgment): (state)
○: No foreign body sensation when touching the residue (not powdered): Good ×: Foreign body sensation when touching the residue (powdered): Defective

(D. Evaluation of emulsification stability)
Each sample was stored in a constant temperature bath at 40 ° C. for 6 months, and the state within 6 months was visually confirmed and judged according to the following criteria.
4-step judgment criteria (judgment): (appearance condition)
◎: No change within 6 months: Very good ○: No creaming is observed within 1 month,
Creaming is observed within 6 months: Good △: Creaming is not observed within 1 week,
Creaming is observed within 1 month: Slightly defective ×: Creaming is observed within 1 week: Defective

As is clear from the results in Tables 1 to 4, the oil-in-water emulsified compositions of Examples 1 to 13 have no firmness, elasticity, or stickiness of the skin as compared with the oil-in-water emulsified compositions of Comparative Examples 1 to 14. It was excellent in the absence of powder blowing and the stability of emulsification.
Further, with respect to Comparative Example 4 containing nicotinamide, sodium ascorbate, and sodium metasilicate, which are components excellent in "skin beam improving effect" and "skin wrinkle improving effect" shown in Patent Document 2. When Example 1 was compared, Example 1 was superior in all of skin firmness / elasticity, no stickiness, no powder blowing, and emulsion stability.
Among them, it is surprising that Example 1 was excellent in emulsification stability, and Comparative Example 3 containing another water-soluble polar substance in place of the component (A) nicotinamide of Example 1. With respect to 4, 5 and 6, the emulsification stability deteriorated. Therefore, it was suggested that among the water-soluble polar substances, nicotinamide in particular can maintain good emulsion stability.

Example 14: Oil-in-water emulsified cream (ingredient) (%)
1.1,3-butylene glycol 12.0
2. 2. Glycerin 5.0
3. 3. Remaining amount of purified water 4. Nicotinamide 6.0
5. Sodium ascorbate 0.5
6. Sodium metasilicate 0.05
7. Hydrogenated lecithin (Note 1) 0.5
8. Hydrogenated lysolecithin (Note 3) 0.5
9. Polyoxyethylene sorbitan monooleate (20EO) (HLB = 13.9)
0.5
10. Glyceryl glyceryl acid (caprylic caprin) 2.0
11. Ceramide 2 0.1
12. Astaxanthin 0.1
13. Tocopherol 0.01
14. Setostearyl alcohol 2.0
15. Behenyl alcohol 1.0
16. Glycerin monostearic acid ester 1.0
17. Methyl paraoxybenzoate 0.05
18. Carbomer 0.15
19. Xanthan gum 0.1
20. Sodium hydroxide 0.004
21. Fragrance 0.05
(Note 3) LP70H (manufactured by Nippon Fine Chemical Co., Ltd.)

(Production method)
A: The components (1) to (6) are uniformly dissolved and mixed at 70 ° C.
B: The components (7) to (16) are uniformly dissolved and mixed at 80 ° C.
C: B is added to A and emulsified at 70 ° C.
After adding and mixing the components (17) to (21) to D: C, the mixture was cooled to 40 ° C. to obtain an oil-in-water emulsified cream.

The oil-in-water emulsified cream of Example 14 was excellent in all of skin firmness / elasticity, no stickiness, no powder blowing, and emulsification stability.

Example 15: Underwater oil mold base
(Ingredient) (%)
1.1,3-butylene glycol 7.0
2. 2. Dipropylene glycol 5.0
3. 3. Triethanolamine 0.4
4. Remaining amount of purified water 5. Nicotinamide 6.0
6. Hydrogenated lecithin (Note 1) 0.4
7. Stearic acid 1.0
8. PEG-80 hydrogenated castor oil (HLB: 14.6) 0.2
9. Sorbitan sesquiisostearate (HLB: 4.5) 0.1
10.2-Setyl ethylhexanoate 2.0
11. Setostearyl alcohol 0.3
12. Behenyl alcohol 0.5
13. Methyl paraoxybenzoate 0.02
14. Talc 0.4
15. Hydrous silica 0.1
16. Mica 1.3
17. Titanium oxide 6.0
18. Iron oxide 0.1
19. Acrylic acid / methacrylic acid alkyl copolymer (Note 2) 0.3
20. Xanthan gum 0.1
21. Sodium hydroxide 0.008
22. Glycine 0.01
23. Arginine 0.01
24. Fragrance 0.01

(Production method)
A: The components (1) to (5) are uniformly dissolved and mixed at 70 ° C.
B: The components (6) to (13) are uniformly dissolved and mixed at 80 ° C.
C: B is added to A and emulsified at 70 ° C.
After adding and mixing the components (14) to (24) to D: C, the mixture was cooled to 40 ° C. to obtain an oil-in-water type substrate.

The underwater oil type base of Example 15 was excellent in all of skin firmness / elasticity, no stickiness, no powder blowing, and emulsification stability.

Example 16: Underwater oil-type beauty essence
(Ingredient) (%)
1.1,3-butylene glycol 5.0
2. 2. Glycerin 5.0
3. 3. Remaining amount of purified water 4. Nicotinamide 6.0
5. Hydrogenated lecithin (Note 4) 0.4
6. Lecithin hydroxide solution (Note 5) 0.2
7. Triceteares 4-phosphate (HLB: 10.5) 0.15
8. Squalene 5.0
9. Linoleic acid 0.05
10. Ceramide 3 0.1
11. Tocopherol 0.01
12. Setostearyl alcohol 0.5
13. Oleyl alcohol 1.0
14. Methyl paraoxybenzoate 0.01
15. Carbomer 0.15
16. (Na acrylate / Na acryloyldimethyltaurine) copolymer solution (Note 6)
0.1
17. Sodium hydroxide 0.05
18. Ethanol 5.0
19. Sodium hyaluronate 0.01
20. Hydrolyzed hyaluronic acid 0.01
21. Hydrolyzed collagen 0.01
22. Glycosyl trehalose 0.1
23. Fragrance 0.1
(Note 4) Resinol S-10EZ (manufactured by Nikko Chemicals)
(Note 5) Resinol WS-50 (manufactured by Nikko Chemicals)
(Note 6) SIMULGEL EG (manufactured by SEPIC)

(Production method)
A: The components (1) to (4) are uniformly dissolved and mixed at 70 ° C.
B: The components (5) to (13) are uniformly dissolved and mixed at 80 ° C.
C: B is added to A and emulsified at 70 ° C.
After adding and mixing the components (14) to (23) to D: C, the mixture was cooled to 40 ° C. to obtain an oil-in-water beauty essence.

The oil-in-water beauty essence of Example 16 was excellent in all of skin firmness / elasticity, no stickiness, no powder blowing, and emulsification stability.

Claims (6)

The following components (A) to (F):
(A) Nicotinamide 1-10% by mass
(B) Phospholipid 0.1-2% by mass
(C) Nonionic surfactant having an HLB of 7 or more 0.02 to 1% by mass
(D) Oil agent liquid at 25 ° C. (E) Polyhydric alcohol 5 to 20% by mass
(F) An oil-in-water emulsified composition containing water. The oil in water according to claim 1, wherein the component (C) is one or more selected from polyoxyethylene castor oil, polyoxyethylene alkyl ether phosphoric acid, polyoxyethylene phytosterol ether, and polyoxyethylene cholesteryl ether. Molded emulsifying composition. The oil-in-water emulsified composition according to claim 1 or 2, further comprising a solid or semi-solid higher alcohol at 25 ° C. of the component (G). The invention according to any one of claims 1 to 3, wherein the component (A) and the content mass ratio (A) / ((B) + (C)) of the component (B) and the component (C) are 1 to 10. Oil-in-water emulsified composition. Any of claims 1 to 4, wherein the content mass ratio (A) / ((D) + (E)) of the component (A) to the component (D) and the component (E) is 0.05 to 0.5. The oil-in-water emulsified composition according to the product. The oil-in-water emulsified composition according to any one of claims 1 to 5, which is a cosmetic or an external preparation for skin.