JP2019142825A - Oil-in-water emulsion composition - Google Patents

Abstract

To provide an oil-in-water emulsion composition that is stable and has a good use feeling by preventing an emulsion state from deteriorating due to the existence of a skin-whitening agent itself or an electrolyte as its stabilizer.SOLUTION: An oil-in-water emulsion composition contains (A)-(F): (A) a water-soluble gelator of 0.01-2.0 mass%, (B) a water-soluble thickener of 0.01-1.0 mass%, (C) a gemini-type anionic surfactant of 0.01-2.0 mass%, (D) a water-soluble skin-whitening agent, (E) an electrolyte other than (D), and (F) an oil solution.SELECTED DRAWING: None

Description

The present invention relates to stabilization of an emulsified composition using a fluid gel. Specifically, the present invention relates to an oil-in-water emulsified cosmetic which contains a water-soluble whitening agent and has improved emulsification and stability.

Water-soluble whitening agents such as tranexamic acid and ascorbic acid derivatives are used in various cosmetics, but they are often unstable by themselves, so when blended into cosmetics, various electrolytes are used in combination. Often used. Therefore, for example, when a water-soluble whitening agent is blended with an oil-in-water emulsion cosmetic containing a carboxyvinyl polymer that is widely used as a thickener, the viscosity is significantly reduced due to the presence of an electrolyte, and the form and stability of the preparation. There was a problem that could not be kept.

The fluid gel is a uniform and smooth fine gel dispersion structure using a water-soluble gel. By changing the type, blending amount, cooling conditions, shearing method, and the like of the gelling agent and thickener, the gel dispersion structure changes, and products in various forms from liquid to solid are possible. Fluid gel is very excellent from the viewpoint of a thickener and is a composition that is relatively easy to manufacture and suitable for factory production. However, there is no particular knowledge about emulsifiability due to so-called surfactant power (Patent Literature). 1, Patent Document 2).
On the other hand, in terms of the feeling of use, a fresh feeling of use is obtained, but a high moisturizing power like an emulsion cannot be obtained.

The emulsion has a high moisturizing effect by preventing moisture transpiration with an oily component called an emollient while improving the hydration state of the skin with a water-soluble component called a moisturizing agent. However, due to the property of fixing the two immiscible components in a uniform dispersion state, the storage stability tends to be poor, and a state such as creaming and separation is likely to occur. Particularly at high temperatures, the viscosity is likely to decrease and it is difficult to ensure stability.

By the way, when confirming the storage stability of the emulsion, various temperature settings are often made. However, state failures such as separation and creaming are not simple kinetic behaviors that progress proportionally with increasing temperature.
That is, just because it is stable under a specific temperature condition does not necessarily mean that it is stable under other temperature conditions. Therefore, in order to ensure the storage stability of the emulsion, it is very important whether the temperature conditions are set in accordance with the actual conditions. For example, given the recent warming, in order to ensure the stability in the summer after the consumer purchases the product, the long-term state change is over 35 ° C, for example, 40 ° C, which is the highest temperature on a hot day. It is important to make sure that there is no. In addition, when considering logistics transportation in summer, it is desirable to perform a stability test for several days at 60 ° C., for example, in which confirmation is performed at a temperature higher than 50 ° C. even for a short period of time.

Cosmetics and the like are blended with various electrolytes as active ingredients and regulators. However, it is difficult to obtain a sufficient emulsified state of an emulsion containing an electrolyte. Specifically, a state defect such that the emulsified particles become too large or non-uniform occurred, and it was difficult to obtain sufficient separation stability. Moreover, when electrolyte exists, the viscosity increase by a thickener may be inhibited and it becomes difficult to obtain the stabilization effect by a thickener. The specific amount of salt that has an effect on the emulsification state and thickening depends on the type of emulsifier, the thickening mechanism of the thickener, and the ionic species of the salt. The state and separation stability often deteriorate. In the emulsion using the carboxyvinyl polymer and the nonionic surfactant having extremely poor salt resistance, the emulsifiability is lowered and the viscosity is decreased when 0.1% by mass of the salt is added to the whole composition. The separation stability is significantly reduced and the separation stability is significantly reduced. In the case of an emulsion of an ionic emulsifier and a salt-resistant thickener, it is relatively easy to ensure stability even if a salt is added in an amount of about 0.1% by mass with respect to the entire composition. . However, in a multi-salt emulsion in which approximately 0.5% or more of a salt is blended, it is much more difficult to ensure good storage stability with a blending amount of a general emulsifier and a thickener.
Therefore, in order to improve these, attempts have been made to stabilize the emulsification by adding a large amount of salt-resistant thickening agent. There is a drawback that the feeling of use becomes worse due to the occurrence of slack, stickiness, and unfamiliarity.

Various solutions have been studied to solve the above problems.
In Patent Document 3, in a composition containing xanthan gum and low molecular weight agar, a low HLB surfactant is used as an emulsifier, and an oil agent added by using a certain amount of a higher alcohol and another oil agent in combination as an oil agent. It is disclosed that an oil-in-water emulsified composition having a good feeling in use and excellent in storage stability can be obtained. However, even when a water-soluble whitening agent and an electrolyte are added, it is unclear whether the storage stability is excellent.

Patent Document 4 discloses a composition in which a dihydric polyol is blended with low molecular weight agar having an average molecular weight of 10,000 to 60,000 and xanthan gum. In this composition, it is disclosed that by using a low molecular weight agar, a uniform composition suitable for cosmetics can be obtained without requiring an operation of breaking the gel with a particularly high shearing force. Further, it is shown that the emulsion stability is very excellent when an oil component is blended without blending a surfactant.
Even in the case of components that require adjustment with a pH adjuster or the like for stabilization, such as an ascorbic acid derivative, the emulsifiability deteriorates due to the presence of the electrolyte. If the amount of the surfactant is forcibly reduced, the amount of low molecular weight agar and xanthan gum increases, which is not preferable because the influence on the feeling of use increases.

In Patent Document 5, polyglycerin fatty acid ester and glycerin fatty acid ester and / or sorbitan fatty acid ester as surfactant, dilauroyl glutamic acid sodium lysine and water-soluble polymer xanthan gum and carboxyvinyl polymer or alkyl-modified carboxyvinyl polymer, Examples are compositions using ascorbic acid 2-glucoside, sodium citrate, and citric acid as the electrolyte. Even if this composition is an oil-in-water emulsified composition containing an electrolyte, the oil-in-water type has high emulsification stability, little increase in viscosity during low-temperature storage, and excellent usability (ease of removal from a container). It is shown to be an emulsified composition.
Certainly, since xanthan gum with relatively good salt tolerance is used, polyglycerin fatty acid ester and glycerin fatty acid ester and / or sorbitan fatty acid ester, dilauroyl acyl glutamic acid lysine sodium as a surfactant, even if salts are blended By using an emulsifying power obtained by combining the above and an emulsifying machine such as a homomixer, it seems that a product having no problem is obtained immediately after production. However, with the amount of xanthan gum blended in an actual formulation, creaming and separation are likely to occur at high temperatures and it is difficult to maintain the state immediately after production.
Further, in terms of the feeling of use, only those in which a relatively large amount of polyglycerin fatty acid ester, which is the main emulsifier in the claims, is blended are shown. The exemplified monoester of decaglycerin is a viscous solid, and when it is added in a large amount, it tends to have a sticky feeling. Originally, when an electrolyte, which is a whitening component such as magnesium ascorbate phosphate or glucoside ascorbate, is blended, stickiness is particularly likely to occur in terms of use, and this is a major issue for commercialization. It is not desirable that the sticky factor increases.
In terms of storage stability, the temperature setting of the constant temperature stability test is 50 ° C. under the highest temperature condition, and the test period is two months. It is unclear whether the emulsification stability is sufficiently ensured in the use environment in summer and the logistics conditions in summer.

On the other hand, the gemini type anionic surfactant used in the present invention has recently attracted attention as a multifunctional surfactant. Applications are used as emulsifiers, oil gelling agents, skin care ingredients, and the like.
Patent Document 6 discloses a gemini type anionic active agent, dilauroyl glutamic acid sodium lysine as a multi-chain polyhydrophilic surfactant, and an emulsifying polymer (acryloyldimethyltauronium ammonium / VP) copolymer or alkyl-modified carboxyvinyl polymer. And an oil-in-water emulsified composition using an oil agent. These compositions are excellent in the persistence and stability of the oily component to the skin.
However, the exemplified compositions are not shown to be involved in water-soluble whitening agents or salt resistance. In fact, in such cases, they do not have sufficient emulsion stability.

JP 2001-342451 A JP 2000-119166 A JP 2014-31328 A JP2015-145416 JP 2014-73991 A JP 2017-178904 A

An object of the present invention is to obtain a stable and good-use composition in an oil-in-water emulsion composition without deteriorating the emulsified state due to the presence of the whitening agent itself or the electrolyte that is a stabilizer thereof. And

That is, the present invention
(A) 0.01-2.0 mass% of water-soluble gelling agent
(B) 0.01-1.0 mass% of water-soluble thickener
(C) 0.01 to 2.0 mass% of gemini type anionic surfactant
(D) Water-soluble whitening agent (E) Electrolytes other than (D)
(F) The above-mentioned problems are solved by making an oil-in-water emulsion composition characterized by blending oil agents (A) to (F).

  The oil-in-water emulsified cosmetic of the present invention is stable and usable without deterioration of the emulsified state in high temperature storage (40 ° C., 60 ° C.) even in the presence of a whitening agent itself or an electrolyte that is a stabilizer thereof. A good composition can be obtained.

The (A): water-soluble gelling agent in the present invention refers to one having a property of solidifying a solution uniformly in a jelly form by dissolving in water. It corresponds to a sol-gel gel referred to in colloid chemistry, and is a component in which a solution that is made into a sol by heating or the like becomes a gelated solid by an operation such as cooling. For example, in a familiar place, the gel form corresponds to a state like jelly, tokoroten, konjac, or tofu. In other words, it is solid, but it breaks and collapses when an external force of a certain level or more is applied, and then has a property that requires a melting operation such as heating above its melting point in order to solidify uniformly.
(A) The water-soluble gelling agent is not particularly limited. For example, hydrophilic proteins having gelling ability such as gelatin and collagen, agar, curdlan, sclerotium gum, deacylated gellan gum, sodium alginate, Examples thereof include hydrophilic polysaccharides such as tamarind gum, carrageenan, mannan and pectin.
Among these, agar, deacylated gellan gum, sodium alginate, and carrageenan are less susceptible to the influence of salts and ions, and can be used preferably because they can prepare a stable gel with a high melting point. Agar is not particularly limited in jelly strength or average molecular weight. It can be used without problems if it solidifies when left to cool at the working concentration. The method for measuring the jelly strength of agar can be based on the currently used Nikkansui method. In other words, an agar solution with a predetermined concentration (usually 1.5% solution) was prepared, and the gel that had been allowed to stand at 20 ° C. for 15 hours and solidified was allowed to withstand the maximum weight (number of grams) per cm 2 of the surface for 20 seconds. Can be used. Alternatively, catalog values measured by the manufacturer may be used. As a method for measuring the average molecular weight of agar, for example, if it is a weight average molecular weight, it can be measured according to the GPC method by HPLC. Specifically, 0.3 g of agar can be dissolved in 200 mL of distilled water (110 ° C., 5 minutes) and measured using a column (TOSOH TSK-GEL for HPLC, TSK-GEL GMPWXL). Alternatively, catalog values measured by the manufacturer may be used.
As the component (A), a single component may be used, or a plurality of components may be used in combination.

(A) A commercial item can be utilized for a component. In the case of agar, the low-intensity agar is AX-30, AX-100, AX-200, CS-120, CS-110 or low-strength easily soluble agar, UX-30, UX-100, UX- 200, CS-320, UP-37 which is easily soluble agar, S-7 and S-9 which are normal agar, high viscoelastic agar soft (all manufactured by Ina Food Industry Co., Ltd.) and the like can be used. In particular, readily soluble agar is dehydrated and dried as it is without cooling the agar sol. Therefore, the molecular form before the agar molecule is transferred to the double helix is maintained and can be easily dissolved. If it is normal agar, it must be dissolved at 95 ° C. or higher. However, by using easily soluble agar, it can be dissolved by heating at 80 ° C. for 5 minutes or more, and the melting operation becomes very simple. Therefore, when considering actual production, it is desirable that the agar used is easily soluble agar in consideration of prevention of deterioration of active ingredients due to heat and shortening of production time. As the gellan gum subjected to deacylation, Kelcogel and KELCOGEL CG-LA (manufactured by CP Kelco) are suitable examples. In order to further strengthen the gelation, it is desirable to add a salt having a divalent metal ion such as calcium chloride or magnesium chloride. The carrageenan is preferably a kappa body excellent in gelation ability, and examples thereof include GENUGEL WG-108 (manufactured by CP Kelco).

When the blending amount of the component (A) is too large, a solidified insoluble residue such as a residue appears during use. If the amount is too small, sufficient stability cannot be obtained. Therefore, generally the range of 0.01-2.0 mass% in the whole composition is suitable, and 0.1-1.0 mass% is especially preferable.

In the present invention, (B): a water-soluble thickener increases the viscosity of an aqueous solution by blending, and at the use concentration of the present invention, a component that does not cause a change in sol-gel state in colloid chemistry, That is, it is a component having no gelling ability. In other words, it refers to a component having the property that the aqueous solution does not break into an external force and is not disintegrated and solidified (gelled). Moreover, even when it is solidified like a cream, it has the property of maintaining uniformity without breaking or collapsing due to external force.
The (B) water-soluble thickener used in the present invention is not particularly limited. Carboxyvinyl polymer, alkyl-modified carboxyvinyl polymer, sodium polyacrylate, polyacrylamide, polyalkylacrylamide / polyacrylamide copolymer, carboxymethylcellulose, hydrophobized hydroxypropylmethylcellulose, hydrophobically modified polyetherurethane, (acryloyldimethyltaurate ammonium / VP) copolymer And other hydrophilic synthetic polymers such as xanthan gum, native gellan gum, succinoglycan, tamarind gum, guar gum, locust bean gum and other hydrophilic clays such as laponite, bentonite and smectite Examples thereof include hydrophilic thickening compounds such as minerals. Among these, xanthan gum, native gellan gum, alkyl-modified carboxyvinyl polymer, hydrophobized hydroxypropyl methylcellulose, hydrophobically modified polyether urethane, and (acryloyldimethyltaurine ammonium / VP) copolymer are particularly preferably used as the usability and stability improver. By blending these water-soluble thickeners, the gel strength of the resulting gel and the feeling during use can be freely adjusted. Furthermore, 1 type, or 2 or more types can be used together as needed.

  (B) A commercial item can be utilized for a component. For example, as native gellan gum, Kelcogel HM (manufactured by CP Kelco) is suitable. Preferred examples of xanthan gum include Celtrol, Celtrol T, and Keldent (manufactured by CP Kelco). Examples of the tamarind gum include Griloid 6C and Griloid 3S (DSP Gokyo Food & Chemicals). Examples of the hydrophobized hydroxypropyl methylcellulose include Sangelose 60L, Sangerose 90L (manufactured by Daido Kasei Kogyo Co., Ltd.). Examples of the alkyl-modified carboxyvinyl polymer include PEMULEN TR-1, PEMULEN TR-2, and Carbopol ETD-2020 (manufactured by Lubrizol). As the hydrophobic modified polyether urethane, Adecanol GT-700 (manufactured by ADEKA) can be used. ARISTFLEX AVC (manufactured by CLARIANT) can be used as the (acryloyldimethyltaurate ammonium / VP) copolymer.

When the blending amount of the component (B) is too large, it is easy to cause problems such as poor fit and stickiness. If the amount is too small, poor stability such as water separation occurs. Therefore, generally the range of 0.01-1.0 mass% in the whole composition is appropriate, and 0.1-0.5 mass% is especially preferable.

(C): Gemini-type anionic surfactant used in the present invention is a surfactant compound in which two surfactant units composed of an anionic hydrophilic group and a hydrophobic group are bound together by a space holding portion called a spacer. It is.
(C) The gemini-type anionic surfactant is not particularly limited, and examples thereof include diacyl glutamic acid lysine salt. The diacylglutamic acid lysine salt can be synthesized by reacting diacylglutamic acid lysine salt with L-lysine hydrochloride and N-fatty acid acyl-L-glutamic acid anhydride. As a commercially available diacylglutamic acid lysine salt, Perisea L-30: trade name (dilauroylglutamic acid lysine sodium: 29%, water: 71%, manufactured by Asahi Kasei Chemicals Corporation) can be used. In addition, dimyristoyl glutamate ricin sodium, distearoyl glutamate lysine sodium, and the like can be mentioned, but dilauroyl glutamate lysine sodium is preferred. Further, “Jemisurf α142” (dicarboxylic acid having two lauryl groups) may be neutralized with potassium hydroxide or the like.
Although there is no restriction | limiting in the compounding quantity of the gemini type | mold anionic surfactant in this invention, 0.01-2.0 mass% is preferable from a viewpoint of the stability and effect of a formulation, 0.1-1.0 mass% Is more preferable.

The (D): water-soluble whitening agent used in the present invention is not particularly limited, and examples thereof include ascorbic acid glucoside, ascorbic acid magnesium phosphate, ascorbic acid sodium phosphate, tranexamic acid, and arbutin.

The electrolyte other than (E) :( D) used in the present invention is not particularly limited, but examples of the organic acid include citric acid and lactic acid. Examples of the organic base include aminomethylpropanol and triethanolamine. Are phosphoric acid and carbonic acid, inorganic bases such as potassium hydroxide and sodium hydroxide, organic salts such as potassium citrate, sodium lactate and sodium edetate, and inorganic salts such as sodium phosphate and sodium chloride And calcium chloride.
(D) Ascorbic acid glucoside, magnesium ascorbate phosphate, sodium ascorbate phosphate, tranexamic acid, arbutin and the like are electrolyte components in the water-soluble whitening agent, and each has a stable pH range. That is, it is known that poor stability such as coloring, odor change, crystallization, and decomposition of the whitening agent occurs outside a specific pH range. Therefore, by adjusting the electrolyte component other than (D) component such as (E) component organic acid, organic base, inorganic acid, inorganic base, organic salt, inorganic salt, etc., pH is adjusted to ensure stability. It is preferable to do.
For example, ascorbic acid glucoside and tranexamic acid are preferably adjusted to be weakly acidic, and magnesium ascorbic acid phosphate is preferably adjusted to be weakly alkaline. If the pH is not adapted to each, discoloration, odor change, crystallization and the like are likely to occur. Furthermore, if it is a quasi-drug, the stability may be significantly reduced, for example, the quantitative value of the main agent may be degraded below the acceptable range.
The pH of the oil-in-water emulsion composition is not particularly limited and is appropriately adjusted depending on the type of water-soluble whitening agent to be used, but is preferably 4.0 to 9.0 in consideration of the stability of the water-soluble whitening agent. It is more preferable that it is .5 to 8.5.

The (F) oil used in the present invention is not particularly limited, and examples thereof include hydrocarbon oils, ester oils, silicone oils, animal and vegetable oils, phospholipids, higher fatty acids, higher alcohols, fluorine-based oils, and the like. 1 or more types can be used. Any of liquid, semi-solid, and solid can be used at these normal temperatures.

Examples of the hydrocarbon oil include liquid paraffin, hydrogenated polyisobutene, isoparaffin, paraffin, α-olefin oligomer, ozokerite, squalane, pristane, ceresin, squalene, petrolatum, microcrystalline wax, paraffin wax, polyethylene wax and the like.
Examples of ester oils include isononyl isononanoate, isodecyl isononanoate, isotridecyl isononanoate, isostearyl myristate, isopropyl myristate, cetyl 2-ethylhexanoate, octyldodecyl myristate, isopropyl palmitate, 2-ethylhexyl palmitate, stearin Acid butyl, hexyl laurate, myristyl myristate, decyl oleate, hexyl decyl dimethyloctanoate, cetyl lactate, myristyl lactate, octyldodecyl lactate, lanolin acetate, isocetyl stearate, isocetyl isostearate, cholesteryl 12-hydroxystearate, 12 -Phytosteryl hydroxystearate, phytosteryl oleate, ethylene glycol di-2-ethylhexanoate, dipen Erythritol fatty acid ester, alkyl glycol monoisostearate, neopentyl glycol diethylhexanoate, neopentyl glycol dicaprate, glyceryl di-2-heptylundecanoate, pentaerythritol tetra-2-ethylhexanoate, pentaerythritol tetraisostearate, tri- Glyceryl 2-ethylhexanoate, glyceryl tri (caprylic acid / capric acid), glyceryl triisostearate, glyceryl tri (caprylic acid / capric acid / myristic acid / stearic acid), glyceryl trimyristate, glyceryl tricaprylate, glyceryl tricaprate , Glyceryl tri-2-heptylundecanoate, trimethylolpropane triisostearate, trimethylethyl tri-2-ethylhexanoate Propane, (isostearic acid / sebacic acid) ditrimethylolpropane oligoester, erythrityl triethylhexanoate, dipentaerythrityl tripolyhydroxystearate, trehalose esters of isostearic acid, dipentaerythrityl pentaisostearate, diglyceryl triisostearate, diglyceryl tetraisostearate, apple Acid diisostearyl, castor oil fatty acid methyl ester, lanolin fatty acid isopropyl, oleyl oleate, acetoglyceride, 2-heptylundecyl palmitate, diisobutyl adipate, (adipic acid, 2-ethylhexanoic acid, stearic acid) glyceryl oligoester , (2-hexyldecanoic acid / sebacic acid) diglyceryl oligoester, N-lauroyl- L-glutamic acid-2-octyldodecyl ester, di-2-heptylundecyl adipate, hexyl laurate, ethyl laurate, di-2-ethylhexyl sebacate, 2-hexyldecyl myristate, 2-hexyldecyl palmitate, 2-hexyldecyl adipate, diisopropyl sebacate, 2-ethylhexyl succinate, glyceryl triisopalmitate, ethyl acetate, butyl acetate, triethyl citrate, tri (behenic acid / isostearic acid / eicosanedioic acid) glyceryl, (behenic acid) / Eicosandioic acid) glyceryl, (behenic acid / eicosandioic acid) polyglyceryl, bisethoxydiglycol succinate, neopentyl glycol diisononanoate, (polyglyceryl-2 isostearate / dimerlinoleic acid) copoly -, Dimerlinoleic acid hydrogenated castor oil, di (caprylic acid / capric acid) propanediol, diisostearic acid propanediol, polyglyceryl-6 octacaprylate, cyclohexane-1,4-dicarboxylic acid bisethoxydiglycol, etc. .
Examples of the silicone oil include chain polysiloxanes such as dimethylpolysiloxane, methylphenylpolysiloxane, and methylhydrogenpolysiloxane, octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, dodecamethylcyclohexasiloxane, and tetrahydrotetramethylcyclohexane. Examples thereof include cyclic polysiloxanes such as tetrasiloxane, polyoxyethylene polyalkylsiloxanes, and the like.
As animal and vegetable oils and fats, for example, avocado oil, camellia oil, argan oil, macadamia nut oil, corn oil, sunflower oil, mink oil, olive oil, rapeseed oil, egg yolk oil, sesame oil, persic oil, wheat germ oil, sasanqua oil, castor oil , Flaxseed oil, safflower oil, grape seed oil, cottonseed oil, eno oil, soybean oil, peanut oil, tea seed oil, kaya oil, rice bran oil, cinnagiri oil, Japanese kiri oil, jojoba oil, germ oil, evening primrose oil, cacao Fat, coconut oil, owl kernel oil, beef leg oil, owl, hydrogenated palm oil, hydrogenated palm oil, hydrogenated castor oil, beeswax, candelilla wax, cotton wax, carnauba wax, bayberry wax, nukarou, kapok wax, sugarcane wax, lanolin, liquid lanolin, Reduced lanolin, hard lanolin, jojoba wax, shellac wax and the like.

In addition to the above components, other components can be blended within a range not impairing the effects of the present invention. For example, anionic surfactants other than component C, amphoteric surfactants, cationic surfactants, nonionic surfactants, gelling agents / thickeners other than those mentioned above, powders, polyhydric alcohols, higher alcohols, Use lower alcohols, higher fatty acids, ultraviolet absorbers, antioxidants, anti-inflammatory agents, bactericides, preservatives, sequestering agents, fragrances, coloring agents, cosmetic ingredients, and the like as long as the effects of the present invention are not impaired. The manufacturing method can use a conventional method.

The manufacturing method of the oil-in-water type emulsion composition of this invention is not specifically limited. Components are mixed and an oil-in-water emulsion composition can be prepared by a conventional method. It is important to make a fluid gel composition comprising a water-soluble gelling agent and a water-soluble thickener, and the gel may be refined during production to form a fluid gel, or after preparing a fluid gel in advance, an oil-in-water emulsion composition May be mixed.
Since the gel dispersion structure is changed by changing the type, blending amount, cooling condition, shearing method, etc. of the water-soluble gelling agent or water-soluble thickener, use a fluid gel that is appropriately adjusted according to the desired feeling of use. be able to. As a method for producing a fluid gel, for example, a heated solution of a thickening compound such as deacylated gellan gum or a water-soluble gelling agent such as agar and xanthan gum that does not have gelation ability is cooled to a temperature below the gelation temperature. A method of shearing (Patent Document 2), a hydrophilic compound having gelling ability such as agar, and a thickening compound such as xanthan gum having no gelling ability are heated and dissolved, and then allowed to cool to gelation. Then, it can be obtained by a method of pulverizing it with a homomixer or the like (Patent Document 1) or a method of stirring using a low molecular weight agar (Patent Document 4).

EXAMPLES Hereinafter, although an Example is given and this invention is demonstrated, this invention is not limited to these Examples.

The oil-in-water emulsion composition having the composition shown in Table 1 was prepared by the following adjustment method.

(Adjustment method)
In the composition shown in Table 1, all components except the whitening agent, electrolyte, and part of purified water are weighed in a beaker, mixed, heated to 85 ° C and dissolved, and then a desktop homomixer (TK ROBOMICS Ver5.0 Plymix) After being treated at 6000 rpm for 1 minute, the mixture was gradually cooled to 40 ° C. while stirring at 200 rpm with a stirring paddle (manufactured by Three One Motor Shinto Kagaku Co., Ltd.). A whitening agent and an aqueous solution of an electrolyte were added at 40 ° C., and the mixture was further stirred and cooled to 25 ° C. The composition obtained after deaeration under reduced pressure was used as a sample.

(Evaluation items and evaluation methods)
(Feeling of use)
Each sample was evaluated by 20 panelists.
It was applied to the entire face after the face washes and the evaluation items were answered in a questionnaire.
Evaluation was made according to the following criteria. “Ease of spreading to skin”, “Smoothness”, “Smoothness” and “Familiar” evaluated the feeling of use during application. The evaluation criteria for each item are shown below.
In addition, what was not able to be emulsified and evaluated the next day was described as "-".
“Easy extension to skin”
A: More than 15 people answered that they can easily extend to the skin and have a good feeling of use.
○: 8 to 14 people answered that they can be easily extended to the skin and have a good feeling of use.
(Triangle | delta): Four to seven persons answered that it was easy to extend to skin and the usability was good.
X: Three or less people answered that it was easy to extend to the skin and the feeling of use was good.
"Sticky"
A: 15 or more responded that there was no stickiness.
○: 8 to 14 people answered that there was no stickiness.
Δ: 4 to 7 people answered that there was no stickiness.
X: 3 or less responded that there was no stickiness.
"Smoothness"
A: More than 15 people answered that they were not sticky.
○: 8 to 14 people answered that they were not sticky.
Δ: 4-7 responded that they were not sticky.
X: 3 or less responded that it was not sticky.
"Familiarity"
A: More than 15 people answered that they were familiar.
○: 8 to 14 people answered that they were familiar.
Δ: 4 to 7 people answered that they are familiar.
×: Three or less responded that they were familiar.

(Emulsifying)
After preparing the composition having the formulation shown in Table 1, the determination was made the next day. Evaluation was made visually by the following criteria.
A: A glossy and beautiful cream was obtained.
○: A cream having a uniform state with little gloss was obtained.
Δ: barely separated, but not in a uniform state
X: Remarkably separated and could not be emulsified.

(40 ° C storage stability)
A sample was stored at 40 ° C. for 3 months, and any of water separation, oil separation, and creaming was determined to be separated. Evaluation was made visually by the following criteria.
(Double-circle): Separation was not seen but there was no change of a state.
○: Slight separation was observed.
(Triangle | delta): Separation was seen clearly.
X: Remarkable separation was observed.

(60 ° C storage stability)
A sample was stored at 60 ° C. for 1 week, and any of water separation, oil separation, and creaming was determined to be separated. Evaluation was made visually by the following criteria.
A: No separation was observed even after 1 week.
○: No separation was observed after 12 hours, but separation was observed in less than one week.
Δ: No separation was observed after 4 hours, but separation was observed in less than 12 hours.
X: Separation was observed within 4 hours.

(Agar jelly strength)
The method for measuring the jelly strength of agar added to Table 2 is based on the Nisamsui method that is widely used at present. In other words, an agar solution with a predetermined concentration (usually 1.5% aqueous solution) was prepared, and the gel that had been allowed to stand for 15 hours at 20 ° C. and coagulated had a maximum weight (number of grams) that could withstand 20 seconds per cm 2 of the surface. It is what. In this specification, the catalog value measured by the same method was used.
The average molecular weight of agar is the weight average molecular weight. The measuring method followed the GPC method by HPLC. Specifically, 0.3 g of agar was dissolved in 200 mL of distilled water (110 ° C., 5 minutes), and a column (TOSOH TSK-GEL for HPLC, TSK-GEL GMPWXL) was used. In this specification, manufacturer data measured by the same method was used.

(Results) are shown in Table 1 (Example 1, Comparative Examples 1 to 6).

(Discussion)
As a result, Example 1 was an oil-in-water emulsified composition with no stickiness or sliminess, good extensibility to the skin, good fit and good use feeling. Further, even when stored at 40 ° C. for 3 months, there was no separation, and the emulsion stability was good, unchanged from the state immediately after production. Furthermore, no separation was observed even at 60 ° C. for one week, and good stability was obtained, and the storage stability was good.
On the other hand, in the composition (Comparative Example 1) in which agar, which is a water-soluble gelling agent, and xanthan gum, which is a water-soluble thickener, is not used, the usability is good in a relatively good emulsified state immediately after production. However, it was separated at 40 ° C. for one month, and further separated at 60 ° C. in about 4 hours, and the storage stability was poor.
In a composition that does not contain dilauroyl glutamic acid lysine sodium solution, which is a gemini-type anionic surfactant (Comparative Example 2), a mixed solution of ascorbic acid glucoside, which is a water-soluble whitening agent, and an electrolyte such as citric acid is used at the time of manufacture. The emulsified state became worse after the addition, and the whole day was a milky emulsion, but the next day it was separated and the emulsification was insufficient. Therefore, the feeling of use and stability could not be evaluated.
In the case of a composition (Comparative Example 3) containing sodium stearoyl glutamate, which is a single-chain anionic amino acid surfactant, instead of gemini-type anionic surfactant, the emulsified state is rough but separated the next day. Could not be seen. However, significant separation was observed at 40 ° C. for 3 months, and sufficient long-term storage stability was not obtained. However, at 60 ° C., the separation was quite good for 12 hours.
In the composition (Comparative Example 4) in which a large amount of xanthan gum, which is a water-soluble thickener, was blended without blending a water-soluble gelling agent, sufficient emulsification stability was obtained, but since there was too much xanthan gum, it was sticky. It was an evaluation that was not suitable for cosmetics because it had a clear feeling of feeling and a feeling of sliminess, poor extensibility to the skin, and poor fit.
When agar, which is a water-soluble gelling agent, was blended without blending a water-soluble thickener (Comparative Example 5), the usability was also good in a relatively good emulsified state immediately after production. Separation was observed after storage at 40 ° C. for 3 months, and separation was possible even at 60 ° C. for 12 hours, and sufficient storage stability was not obtained.
In the case where no electrolyte other than the water-soluble whitening agent was blended (Comparative Example 6), the emulsifiability was slightly weak on the appearance and it was a mat, but it was judged that there was no particular problem. However, since no electrolyte was blended, the pH was very low at 2.5, and the composition had a high possibility of irritation when applied to the skin. Further, when stored at 40 ° C. for 3 months, it was discolored to yellow, a odor was felt, separation was observed, and storage stability was very poor. In storage at 60 ° C., separation did not occur in 4 hours, but separation was confirmed immediately thereafter.

The oil-in-water emulsified cosmetic composition having the composition shown in Table 3 was prepared by the following adjustment method.

(Adjustment method)
In the formulation shown in Table 3, all components except the whitening agent, electrolyte, and part of purified water are weighed in respective beakers of oil phase and aqueous phase, heated and dissolved until uniformly dissolved, and kept at 85 ° C. After confirming dissolution, the oil phase and the aqueous layer are mixed and emulsified. Then, after processing for 1 minute at 6000 rpm with a desktop homomixer (TK ROBOMICS Ver5.0 manufactured by Plymix), gradually cooled to 40 ° C. while stirring at 200 rpm with a stirring paddle (manufactured by Three One Motor Shinto Kagaku). did. A whitening agent and an aqueous solution of an electrolyte were added at 40 ° C., and the mixture was further stirred and cooled to 25 ° C. The composition obtained after deaeration under reduced pressure was used as a sample.

(Results) are shown in Table 3 (Examples 2 to 6).

(Consideration) About Examples 2-6, it was an oil-in-water type emulsion composition which each has a favorable usability, a good emulsifying property, and storage stability.

The oil-in-water emulsion composition having the composition shown in Table 4 was prepared by the following adjustment method.

(Adjustment method)
In the formulation shown in Table 4, all components other than the whitening agent, the electrolyte and some purified water are weighed in each beaker of the oil phase and the aqueous phase, heated and dissolved until uniformly dissolved, and kept at 85 ° C. After confirming dissolution, the oil phase and the aqueous layer are mixed and emulsified. After processing for 10 minutes at 3500 rpm with a desktop homomixer (TK ROBOMICS Ver5.0 manufactured by Plymix), the mixture was gradually cooled to 40 ° C. while stirring at 100 rpm with a stirring paddle (manufactured by Three One Motor Shinto Kagaku). A whitening agent and an aqueous solution of an electrolyte were added at 40 ° C., and the mixture was further stirred and cooled to 30 ° C. The composition obtained after deaeration under reduced pressure was used as a sample.

(Results) are shown in Table 4 (Example 7, Comparative Examples 7 and 8).

(Consideration) About Example 7, it was an oil-in-water type emulsion composition which has a favorable usability, emulsifiability, and storage stability. In Comparative Example 7, the stability at 40 ° C. was at a level with no problem. As for the stability at 60 ° C., there was no problem in 4 hours, but then separation occurred. Further, the stickiness, sliminess and familiarity were poorly evaluated, and the usability was poor. In Comparative Example 8, the emulsified state was rough and the storage stability was poor.

Below, the prescription | regulation of the oil-in-water type emulsion cosmetics using the structure of this invention, a manufacturing method, and a characteristic are shown.

Formulation Example 1
Whitening Cream Cetanol 1.5%
Ascorbyl tetrahexyl decanoate 0.5%
Methylphenylpolysiloxane 4.0%
Cetyl 2-ethylhexanoate 8.0%
Hydrogenated lecithin 0.2%
POE hydrogenated castor oil (50EO) * 5 1.0%
Purified water make to 100
1.3 Butylene glycol 8.0%
1.2 Hexanediol 0.3%
Native gellan gum * 15 0.05%
Kanten (jelly strength 730 g / cm ² ) * 19 0.1%
Dilauroyl glutamic acid lysine sodium solution * 3 0.5%
Acrylic acid amide mixture * 20 0.5%
Betaine 1.0%
Phenoxyethanol 0.2%
Sodium hyaluronate 1% aqueous solution 2.0%
Purified water 8.0%
Tranexamic acid 1.0%
Citric acid 0.1%
Sodium citrate 0.1%
Edetate disodium 0.005%

* 5 Nikkor HCO-50 Nikko Chemicals * 15 Kelcogel HM CP Kelco * 3 Perisea L-30 (29% aqueous solution) Asahi Kasei Chemical * 19 Kanten S-7 Ina Foods * 20 Sepigel 305 SEPPIC

(Manufacturing method)
In the formulation shown in Formulation Example 1, components other than the 1% aqueous solution of sodium hyaluronate, the whitening agent, and the aqueous electrolyte solution were weighed in an oil phase and an aqueous phase beaker, respectively, and the oil phase was kept at 85 ° C., and the aqueous phase was uniform. Dissolve by heating to 95 ° C. After confirming dissolution, the oil phase and the aqueous layer are mixed and emulsified. After processing for 10 minutes at 3500 rpm with a desktop homomixer (TK ROBOMICS Ver5.0 manufactured by Plymix), the mixture was gradually cooled to 60 ° C. while stirring at 100 rpm with a stirring paddle (manufactured by Three One Motor Shinto Kagaku). At 60 ° C., a 1% aqueous solution of sodium hyaluronate, a whitening agent, and an aqueous solution of an electrolyte were added, and the mixture was further cooled to 50 ° C. with stirring. Then, it was left to cool. The next day, the completely gelled bulk was treated with a homomixer at 6000 rpm for 5 minutes to form a uniform cream, then degassed under reduced pressure, and the resulting composition was used as a sample.

  Formulation Example 1 was a creamy oil-in-water whitening composition having good usability, emulsifying properties, and storage stability.

Formulation example 2
Sunscreen whitening cream UV absorber, whitening sunscreen cosmetics with UV light scattering agent Stearyl glycyrrhizinate 0.05%
Ethylhexyl triazone 1.0%
Octocrylene 1.0%
Diethylaminohydroxybenzoyl hexyl benzoate 0.5%
Ethylhexyl methoxycinnamate 3.0%
Sucrose triacetate tetrastearate 2.0%
Behenyl alcohol 1.5%
Cetanol 1.5%
Isotridecyl isononanoate 2.0%
Pentaerythrityl tetraethylhexanoate 2.0%
Dimethicone (5cs) 2.0%
Sorbitan sesquioleate 1.0%
d-δ Tocopherol 0.1%
Ethylhexyl glycerin 0.2%
PEG-9 polydimethylsiloxyethyl dimethicone 0.3%
Isododecane 3.0%
Purified water make to 100
1. 3-butylene glycol 9.0%
Xanthan gum * 17 0.2%
(Vinyl dimethicone / methicone silsesquioxane) cross-polymer powder * 21 1.5%
Kanten (jelly strength 700 g / cm ² ) * 1 0.3%
Dilauroyl glutamic acid lysine sodium solution * 3 0.5%
Arbutin 0.1%
1.2 Octanediol 0.2%
Stearic acid PEG-55 0.8%
Butylcarbamate propynyl iodide solution * 22 0.05%
Acetylated sodium hyaluronate 1% aqueous solution 1.0%
Ultraviolet absorber-encapsulated microcapsules * 23 9.0%
Fine particle titanium oxide aqueous dispersion * 24 10.0%
(Hydroxyethyl acrylate / acryloyldimethyltaurine Na) copolymer mixture * 25 0.3%
Purified water 8.0%
Citric acid 0.03%
Trisodium citrate 0.4%
Potassium hydroxide 0.36
Ascorbic acid glucoside 2.0%
Myristyl glyceryl ascorbic acid 0.2%
Ethanol 5.0%

* 17 Celtolol T CP Kelco * 1 Kanten UP-37 (Insoluble Agar) Ina Foods * 3 Perisea L-30 (29% aqueous solution) Asahi Kasei Chemical * 21 KSP-100 Shin-Etsu Silicone * 22 GLYCASIL 2000 LONZA * 23 SILASOMA MEA (L) Seiwa Kasei * 24 WT-PF01 Teica * 25 SEPINOV EMT10 SEPPIC

(Manufacturing method)
In the formulation shown in Formulation Example 2, components other than those added at 50 ° C. are weighed in an oil phase and an aqueous phase beaker, respectively, and heated to 85 ° C. where they are uniformly dissolved. After confirming dissolution, the oil phase and the aqueous layer are mixed and emulsified. After processing at 6000 rpm for 1 minute with a desktop homomixer (TK ROBOMICS Ver5.0 manufactured by Plymix), the parts were replaced with a disper mixer and gradually cooled to 50 ° C. while stirring at 1000 rpm. Add 50% acetylated sodium hyaluronate aqueous solution and microcapsules containing UV absorber, fine particle titanium oxide aqueous dispersion, (hydroxyethyl acrylate / acryloyldimethyltaurine Na) copolymer mixture, whitening agent, electrolyte aqueous solution, ethanol at 50 ° C Further, the mixture was cooled to 25 ° C. while stirring at 1000 rpm with a disper mixer. Then, it deaerated under reduced pressure and the obtained composition was made into the sample.

    Formulation Example 2 was a creamy oil-in-water whitening composition having good usability, emulsifying properties, and storage stability. Further, good sunscreen effects such as SPF30 and PA ++ were obtained.

Formulation Example 3
Sunscreen whitening milk UV-absorbing whitening sunscreen cosmetic ethyl hexyl triazone 1.0%
Dimethicoethyl benzal malonate 0.5%
Bisethylhexyloxyphenol methoxyphenyltriazine 1.0%
Ethylhexyl methoxycinnamate 4.0%
1.0% sucrose tristearate tetrastearate
Cetanol 1.5%
Isotridecyl isononanoate 3.0%
Pentaerythrityl tetraethylhexanoate 1.0%
Sorbitan sesquioleate 2.0%
d-δ Tocopherol 0.1%
Ethylhexyl glycerin 0.2%
Isododecane 3.0%
Purified water make to 100
1.3 Butylene glycol 9.0%
1.2 Pentanediol 0.4%
Xanthan gum * 2 0.05%
Kanten (jelly strength 200 g / cm ² ) * 7 0.5%
Dilauroyl glutamic acid lysine sodium solution * 3 0.5%
PEG-55 stearic acid 0.5%
Butylcarbamate propynyl iodide solution * 22 0.05%
Hydrolyzed hyaluronic acid 1% aqueous solution 1.0%
Ultraviolet absorber inclusion microcapsule * 23 10.0%
(Na-acrylate / acryloyldimethyltaurine-Na) copolymer mixture * 26 0.3%
Purified water 8.0%
Citric acid 0.03%
Trisodium citrate 0.4%
Potassium hydroxide 0.36
Ascorbic acid glucoside 2.0%
Ethyl ascorbic acid 0.2%

* 2 Keldent CP Kelco * 7 Kanten UX-200 (low-strength easily soluble agar) Ina Foods * 3 Perisea L-30 (29% aqueous solution) Asahi Kasei Chemical * 22 GLYCASIL 2000 LONZA * 23 SILASOMA MEA (L) Made by Seiwa Kasei Co., Ltd. * 26 Made by SIMULGEL EG SEPPIC

(Manufacturing method)
In the formulation shown in Formulation Example 3, components other than those added at 50 ° C. are weighed in an oil phase and an aqueous phase beaker, respectively, and heated to 85 ° C. where they are uniformly dissolved. After confirming dissolution, the oil phase and the aqueous layer are mixed and emulsified. After processing for 1 minute at 10,000 rpm with a desktop homomixer (TK ROBOMICS Ver5.0 manufactured by Plymix), the mixture was gradually cooled to 50 ° C. while stirring at 100 rpm with a stirring paddle (manufactured by Three One Motor Shinto Kagaku). Add hydrolyzed 1% aqueous solution of hyaluronic acid and UV absorber-encapsulated microcapsules, (acrylic acid Na / acryloyldimethyltaurine Na) copolymer mixture, whitening agent, and aqueous electrolyte solution at 50 ° C., and further reduce the stirring paddle at 80 rpm. The mixture was stirred and cooled to 20 ° C. The obtained composition was used as a sample.

  Formulation Example 3 was an emulsion oil-in-water whitening composition having good usability, emulsifying properties, and storage stability. Furthermore, good sunscreen effects such as SPF25 and PA ++ were obtained.

Formulation Example 4
Whitening foundation setanol with pigment 1.5%
Dipentaerythritol fatty acid ester 1.5%
Ascorbyl tetrahexyl decanoate 0.5%
Methylphenylpolysiloxane 4.0%
Cetyl 2-ethylhexanoate 8.0%
Diglyceryl monoisostearate 1.0%
Isostearic acid-treated red iron oxide 0.9%
Isostearic acid-treated yellow iron oxide 1.6%
Isostearic acid-treated black iron oxide 0.2%
Triethoxycaprylylsilane-treated titanium oxide 3.0%
Spherical polymethyl methacrylate powder 2.0%
Hydrogenated lecithin 0.2%
Ceramide 3 0.003%
Purified water make to 100
1.3 Butylene glycol 8.0%
Concentrated glycerin 5.0%
Xanthan gum * 2 0.2%
Kanten (jelly strength 700 g / cm ² ) * 1 0.5%
Dilauroyl glutamic acid lysine sodium solution * 3 0.5%
Hydrophobized hydroxypropyl methylcellulose * 12 0.2%
Betaine 1.0%
Phenoxyethanol 0.2%
Sodium hyaluronate 1% aqueous solution 1.0%
Purified water 8.0%
Citric acid 0.03%
Trisodium citrate 0.4%
Potassium hydroxide 0.36
Ascorbic acid glucoside 2.0%
Ascorbyl palmitate trisodium 0.2%
Edetate disodium 0.005%

* 2 Keldent CP Kelco * 7 Kanten UP-37 (low-strength easily soluble agar) Ina Foods * 3 Perisea L-30 (29% aqueous solution) Asahi Kasei Chemical * 12 Sangellos 60L Daido Kasei Kogyo

(Manufacturing method)
In the formulation shown in Formulation Example 4,
In advance, the pigment is roller-treated using an oil agent and diglyceryl monoisostearate.
Components other than those added at 50 ° C. are weighed in an oil phase and an aqueous phase beaker, respectively, and heated to 85 ° C. where they are uniformly dissolved to dissolve. After confirming dissolution, the oil phase and the aqueous layer are mixed and emulsified. After processing for 3 minutes at 4000 rpm with a desktop homomixer (TK ROBOMICS Ver5.0 manufactured by Plymix), the mixture was gradually cooled to 50 ° C. while stirring at 100 rpm with a stirring paddle (manufactured by Three One Motor Shinto Kagaku). A sodium hyaluronate 1% aqueous solution, a whitening agent and an aqueous solution of an electrolyte were added at 50 ° C., and the mixture was further cooled to 20 ° C. while stirring at 80 rpm with a stirring paddle. Then, it deaerated under reduced pressure and the obtained composition was made into the sample.

  Formulation Example 4 was a creamy oil-in-water whitening composition having good usability, emulsifying properties, and storage stability. Furthermore, it was an excellent foundation for makeup.

Formulation Example 5
Whitening whitening lotion essence Native gellan gum * 15 0.05%
Kanten (jelly strength 10 g / cm ² ) * 9 0.3%
Purified water 20%
Methylphenylpolysiloxane 1.0%
POE hydrogenated castor oil (50EO) * 5 0.5%
Ethanol 95% native 4.0%
Purified water make to 100
Propylene glycol 4.0%
Dilauroyl glutamate lysine sodium solution * 3 0.2%
Betaine 1.0%
Phenoxyethanol 0.2%
Water-soluble collagen aqueous solution 1.0%
Purified water 8.0%
Citric acid 0.03%
Trisodium citrate 0.4%
Potassium hydroxide 0.36
Ascorbic acid glucoside 2.0%
Ascorbyl palmitate trisodium 0.2%
Edetate disodium 0.005%

* 5 Nikkor HCO-50 Nikko Chemicals * 15 Kelcogel HM CP Kelco * 9 Ina (low strength, easily soluble agar) Ina Foods * 3 Perisea L-30 (29% aqueous solution) Asahi Kasei Chemical

(Manufacturing method)
In the formulation shown in Formulation Example 5, native gellan gum, agar and purified water are heated up to 85 degrees in advance and dissolved. Thereafter, the mixture is cooled to 25 degrees with stirring to obtain a fluid gel solution.
Ingredients other than those added at 45 ° C. are weighed in an oil phase and an aqueous phase beaker, respectively, and heated to 80 ° C. where they are uniformly dissolved. After confirming dissolution, the oil phase and the aqueous layer are mixed and emulsified. After processing at 4000 rpm for 3 minutes with a desktop homomixer (TK ROBOMICS Ver5.0 manufactured by Primix), the mixture was cooled to 50 ° C. while stirring at 100 rpm with a stirring paddle (manufactured by Three One Motor Shinto Kagaku). A fluid gel solution was added at 50 ° C., an aqueous collagen solution, a whitening agent and an aqueous solution of electrolyte were added at 45 ° C., and the mixture was further cooled to 40 ° C. while stirring at 80 rpm with a stirring paddle under reduced pressure. Thereafter, the obtained composition was used as a sample.

  Formulation Example 5 was a cloudy liquid oil-in-water whitening composition having good usability, emulsifying properties, and storage stability.

Formulation Example 6
Whitening lotion methylphenylpolysiloxane 0.2% which puts in spray (no propellant) and becomes a beautiful radiation pattern
Decaglycerin monoisostearate 0.1%
Ethanol 95% native 4.0%
Purified water make to 100
Concentrated glycerin 4.0%
Methyl glucoside 1.0%
Xanthan gum * 2 0.05%
Kelcogel * 11 0.3%
Dilauroyl glutamate lysine sodium solution * 3 0.2%
Betaine 1.0%
Phenoxyethanol 0.2%
Calcium chloride 0.03%
Water-soluble collagen aqueous solution 1.0%
Purified water 8.0%
Citric acid 0.03%
Trisodium citrate 0.4%
Potassium hydroxide 0.36
Ascorbic acid glucoside 2.0%
Edetate disodium 0.005%

* 11 Kelcogel CP Kelco * 2 Keldent CP Kelco * 3 Perisea L-30 (29% aqueous solution) Asahi Kasei Chemical

(Manufacturing method)
In the formulation shown in Formulation Example 5, the components other than those added at 45 ° C. are weighed in beakers of an alcohol phase and an aqueous phase, respectively, and the aqueous phase is heated to 90 ° C. and dissolved. After confirming dissolution of the aqueous phase, the mixture is stirred and cooled to 50 degrees, and the alcohol phase is added to emulsify. The mixture was gradually cooled to 45 ° C. while stirring at 100 rpm with a stirring paddle (manufactured by Three One Motor Shinto Kagaku Co., Ltd.). A water-soluble collagen aqueous solution, a whitening agent, and an aqueous solution of an electrolyte were added at 45 ° C., and the mixture was further cooled to 25 ° C. while stirring at 100 rpm with a stirring paddle under reduced pressure. Thereafter, the obtained composition was used as a sample.

  Formulation Example 6 had an emulsion viscosity in appearance, but when filled in a spray bottle and used, it could be uniformly dispersed in a fine mist. Further, it was a liquid oil-in-water type whitening composition having a good feeling of use, emulsifying properties and storage stability.

Formulation Example 7
Bulk of mousse-form foundation formulation example 4 in aerosol container 92.0%
LPG 8.0%
Fill an aerosol can, and spout it out.

  Formulation Example 7 was discharged in a fine mousse shape. It was a foundation that could be applied uniformly with good elongation. In addition, it had excellent makeup.

ADVANTAGE OF THE INVENTION According to this invention, the oil-in-water type cosmetics which were excellent in the stability which included the water-soluble whitening agent and the thickener over time can be provided.

Claims (9)

(A): 0.01-2.0 mass% of water-soluble gelling agent
(B): 0.01-1.0 mass% of water-soluble thickener
(C): Gemini type anionic surfactant 0.01-2.0 mass%
(D): Water-soluble whitening agent (E): Electrolyte other than (D) (F): Oil-in-water type emulsion composition containing oil agents (A) to (F) 2. The oil-in-water emulsion composition according to claim 1, wherein (A) is at least one selected from agar, carrageenan, deacylated gellan gum, and sodium alginate. (B) is one or more selected from xanthan gum, tamarind gum, native gellan gum, alkyl-modified carboxyvinyl polymer, hydrophobized hydroxypropyl methylcellulose, hydrophobically-modified polyether urethane, and (acryloyldimethyltaurine ammonium / VP) copolymer. The oil-in-water emulsion composition according to 1 or 2 4. The oil-in-water emulsion composition according to claim 1, wherein (C) is diacyl glutamic acid lysine salt. 5. The oil-in-water emulsion composition according to claim 1, wherein (D) is at least one selected from ascorbic acid derivatives and salts thereof, tranexamic acid, and arbutin. 6. The oil-in-water emulsion composition according to claim 1, wherein (E) is at least one selected from organic salts, inorganic salts, organic acids, inorganic acids, organic bases and inorganic bases. 7. The oil-in-water emulsion composition according to claim 1, wherein (F) is at least one selected from hydrocarbon oils, ester oils, and silicone oils. The oil-in-water emulsion composition according to any one of claims 1 to 6, wherein the ascorbic acid derivative of (D) and a salt thereof are at least one selected from ascorbic acid glucoside, magnesium ascorbate phosphate, and sodium ascorbate phosphate. 9. The oil-in-water emulsion composition according to claim 1 having a pH of 4.0 to 9.0.